title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Membranes of Rhodospirillum rubrum: physicochemical properties of chromatophore fractions isolated from osmotically and mechanically disrupted cells. | Isolation of highly purified membrane fractions from phototrophically grown Rhodospirillum rubrum was achieved by velocity and isopyknic sedimentation under carefully controlled ionic conditions. Bacteriochlorophyll-rich and succinic dehydrogenase-rich chromatophores that were essentially devoid of contamination by non... | 820,690 | [
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Preparation and properties of trypsin-digested ribonuclease T1 split at the single arginyl peptide bond. | Ribonuclease T1 [EC 3.1.4.8] was selectively hydrolyzed by digestion with trypsin at the peptide bond of the single arginine residue at position 77. Selective hydrolysis was achieved by blocking the xi-amino group of Lys-41 with 2-methoxy-5-nitrotropone and subsequent digestion with trypsin in the presence of 2M urea. ... | 820,695 | [
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Secretion of alpha subunit of glycoprotein hormones by pituitary adenomas. | In 60 patients with pituitary adenomas, the serum concentration of the alpha subunit of the glycoprotein hormones (serum alpha) was measured by a sensitive and specific radioimmunoassay. Five patients had markedly elevated serum alpha prior to therapy (range 14.5-23.0 ng/ml). These 5 patients included 2 hyperthyroid me... | 820,707 | [
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Angiographic study of the effect of laminectomy in the presence of acute anterior epidural masses. | Laminectomies were performed in 16 monkeys to decompress simulated acute epidural masses in front of the spinal cord. When decompression restored normal arterial and venous hemodynamics, the monkeys were neurologically intact in spite of considerable mechanical distortion of the cord. When either the anterior spinal ar... | 820,838 | [
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Biphasic modulation of potassium release in rat parotid gland by carbachol and phenylephrine. | Both 86Rb and 42K appeared to serve as useful markers for potassium movements in rat parotid gland slices. Carbachol and phenylephrine elicited a biphasic increase in potassium release (86Rb release) that was dose related and could be blocked by atropin and phentolamine, respectively. The early transient phase of 86Rb ... | 820,851 | [
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Irreversible activation of adenylate cyclase of toad erythrocyte plasma membrane by 5'-guanylylimidodiphosphate. | The irreversible activation of adenylate-cyclase by 5'guanylylimidodiphosphate, a phosphoramidate analog of 5'GTP, has been examined in toad (Bufus marinus) plasma membranes using the technique of preincubating the membranes with the nucleotide under various controlled conditions followed by washing and subsequent assa... | 820,859 | [
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Isolation and characterization of tox mutants of corynebacteriophage beta. | Seventeen nontoxinogenic (tox) mutants of corynebacteriophage beta have been isolated by using a tissue culture screening technique. The mutants fall into four major classes. Two of the classes, I and II, appear to contain missense and nonsense mutants, respectively. However, classes III and IV have not been previously... | 820,873 | [
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R factor-mediated resistance to aminoglycoside antibiotics in Pseudomonas aeruginosa. | Conjugal transferability of drug resistance was examined, in eleven Pseudomonas aeruginosa strains which were isolated in Frankfurt. Four R factors were demonstrated from three strains using P. aeruginosa as recipients but they were nontransferable to Escherichia coli K12. Two R factors, i.e., Rms146 and Rms147, mediat... | 820,894 | [
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Thyroid function in changing weather in a subtropical region. | Serum and 24-hr urine samples were collected on 2 consecutive days during the first week of each month for 1 yr from eight healthy euthyroid men aged 25-37 yr. The means of minimum and maximum environmental temperature for the 30 days period preceding the sample collection represented the temperature for that month. To... | 820,939 | [
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An evaluation of multiphasic screening on admission to hospital. Precis of a report to the National Health and Medical Research Council. | A controlled study of admission multiphasic screening (AMS) at a large general hospital showed that AMS had no significant effect on a variety of indices of inpatient progress. Owing to a 64% increase in estimated cost of investigations with AMS, the total hospital admission cost was increased by approximately 5%. Unde... | 820,955 | [
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[The treatment of ptyalism in children with cerebral lesions (author's transl)]. | Even after coarse movements have largely become normal, a distrubed motoricity and sensitivity remains in the orofacial region of some children with cerebral lesions, with disordered function of the transport of saliva and masticated food. So far, we have treated 9 children with moderately severe to slight degrees of c... | 820,969 | [
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[Gilbert's jaundice. Current clinico-nosographic physiopathological and therapeutical aspects. I. Recent findings in Gilbert's syndrome]. | Gilbert's icterus is a term used to cover certain forms of free bilirubin hyperbilirubinaemia which occur without any clear signs of hyperhaemolysis and are thus based on a fundamental defect in bilirubin liver cell clearance. Speculatively, this defect may be considered as being located at the level of any one of the ... | 821,019 | [
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The influence of bufotenin on the feeding behavior and cerebral serotonin content in rats. | By researches carried out in male adult rats (Wistar), the influence of the intraperitoneally injected bufotenin (5 mg/kg b.w. active substance in saline solution) was followed on: I--feeding behavior; II--the serotonin concentration in hypothalamus, rhinencephalon, mesencephalon and sensorimotor cerebral cortex. The o... | 821,071 | [
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Comparison between total and renal plasma clearance of [51Cr] EDTA. | The total plasma (Et) and renal plasma (Er) clearances of [51Cr]EDTA were measured simultaneously in 40 patients with a wide range of renal function. The regression equation was Et identical to 0.997 Er+4.1; the slope of the regression line was not significantly different from 1.00, and the intercept differed significa... | 821,136 | [
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Stimulation of the non-specific resistance by Corynebacterium parvum and Bacillus calmette Guérin. | The effect of pretreatment of intravenously administered killed Corynebacterium parvum (CP) and living BCG was studied in various model systems. Both vaccines caused an increased resistance to Listeria monocytogenes, indicating macrophage activation. Only CP exerted a suppressive effect on T-cell-mediated immunological... | 821,172 | [
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[An integrated measurement system for betatron systems used in radiotherapy]. | A new measuring system is described which is able to measure the dose applicated by a betatron by means of two redundant dose monitors and to control the dose distribution by a special chamber arrangement. The measuring system is completed by control equipments and a digital dose rate and energy measuring unity. | 821,182 | [
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[Electron microscope studies on developmental stages of Theileria parva (Theiler, 1904) in the intestine of the tick Hyalomma anatolicum excavatum (Koch, 1844) (author's transl)]. | The developmental stages of Theileria parva within the intestine of ticks were studied by electron microscopy. On the 2nd-4th day post repletionem (p.r.) the intestine of the ticks contained numerous stages, which were very similar to microgamonts and microgametes of haemosporidia. From these results it seemed likely t... | 821,188 | [
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[Hormonal methods of increasing fertility in swine]. | Experiments were carried out to raise the conception rate in sows during the summer season under industrial conditions of breeding. Eight test groups of 365 animals were formed as well as four control ones with 137 pigs. The sucking period lasted 28 to 33 days. When in estrus the sows were mated with boars twice at a 2... | 821,208 | [
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The endothelial surface of growing coronary collateral arteries. Intimal margination and diapedesis of monocytes. A combined SEM and TEM study. | Slowly progressing coronary artery stenosis leading to complete occlusion within about 3 weeks was produced in dogs. Within this time collateral vessels had enlarged sufficiently to prevent myocardial infarction. Early, intermediate, and late (1 year after occlusion) stages of collateral development were studied with t... | 821,235 | [
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Squamous epithelial cancer in metaplastic pleura following extrapleural pneumothorax for pulmonary tuberculosis. | During the period 1947-1955, 148 patients underwent extrapleural pneumolysis for pulmonary tuberculosis in Stockholm City Chest Hospital at Söderby. In 121 tuberculosis healed following operation. Ten of these later developed pain and a feeling of tension on the operated side and were operated upon with evacuation of t... | 821,237 | [
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[Characteristics of the reaction of the macrophage lysosomal apparatus in guinea pigs immunized with a live and a killed Br. abortus culture]. | Accumulation of fluorescent antigen-antibody complex in the cytoplasmic granules at various time intervals after the phagocytosis of brucellae treated with brucella fluorescent serum was studied in the peritoneal macrophage culture of guinea pigs immunized with live and killed brucella culture. The activity of the lyso... | 821,275 | [
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[The activity of rubrospinal neurons in Macaca mulatta monkeys]. | Action potentials of single cells in nucleus ruber have been recorded extracellularly inresponse to antidromic activation of the rubro-spinal tract and stimulation of contralateral interpositus nucleus of the cerebellum in the monkey M. mulatta. The analysis of the data obtained indicates that both large cells of the c... | 821,269 | [
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Oxymetholone effect of acute myeloblastic leukemia cells in vitro. | The possibility that oxymetholone might induce or enhance leukemia after androgen therapy for aplastic anemia prompted us to study the direct action of oxymetholone on the DNA synthesis of AML cells in vitro. The peripheral blasts of 10 patients, 8 with AML and 2 with CML in blast crisis have been studied. The DNA synt... | 821,291 | [
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Stimulation of phagocytosis by human lysozyme. | Human lysozyme in physiologic concentrations (10--400 mug/ml) significantly (p less than 0.001) stimulates the phagocytosis of yeast cells by human polymorphonuclear leukocytes. This stimulating effect was observed even in the absence of serum factors. Hen egg white lysozyme or protamine sulfate had no effect on phagoc... | 821,293 | [
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Incidence of fractures of the vertebral spine in epileptic patients. | The incidence of vertebral fractures in 87 epileptic outpatients was 16 per cent. The occurrence of vertebral fractures in epileptics was not correlated to age, state of osteomalacia or to type or number of epileptic seizures. | 821,305 | [
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Effect of nitroglycerin on ventricular fibrillation threshold of nonischemic myocardium. | The threshold for ventricular fibrillation induced by a 200 msec train of pulses was measured during a control period and during an intravenous infusion of nitroglycerin in 14 nonischemic open chest dogs. Infusion of nitroglycerin in doses sufficient to reduce mean arterial blood pressure an average of 17 mm Hg was ass... | 821,329 | [
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Malnutrition studies in Macaca mulatta. V. Effect on biochemical and cytochemical composition of major organs. | The effects of control, dilute, and low-protein duets on organ development were evaluated in infant rhesus monkeys. Both experimental duets resulted in growth failure of the cerebral hemisphere, lung, liver, kidney, and muscle and, with few exceptions, in their total organ contents of water, protein, lipid, glycogen, D... | 821,333 | [
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Congenital biliary atresia. Analysis of 97 cases with reference to prognosis after hepatic portoenterostomy. | The prognosis of 97 patients with congenital biliary atresia treated by hepatic portoenterostomy was studied. In 37 of 97 patients (38%), good bile excretion was observed after surgery, and jaundice cleared. Sixteen of the 37 patients developed ascending cholangitis; 11, esophageal varices; and nine died. Seven died of... | 821,337 | [
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0.4614914,
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0.4039244,
0.08813023,
-0.0920... |
Cardiovascular and renal functions in normal rhesus macaques. | Techniques on measurements of cardiovascular and renal functions in conscious rhesus macaques (Macaca mulatta) are described, and normal base line values are presented. The determinations included blood pressure, cardiac dynamics, total peripheral resistance, renal metabolism, renal concentrating capcity, acid-base bal... | 821,371 | [
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Vaccination against bovine brucellosis with a low dose of strain 19 administered by the conjunctival route. I.--Protection demonstrated in guinea pigs. | Guinea pigs were vaccinated with different doses of strain Brucella abortus B 19, subcutaneously (SC) or by the conjunctival route (C), once or a second time three months later. Agglutination and complement fixation titers were determined on sera of guinea pigs taken at random at intervals from each vaccine group. Prot... | 821,381 | [
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0.02229... |
Hydrogen-dependent organisms from the human gingival crevice resembling Vibrio succinogenes. | Twenty-eight strains of microaerophilic, motile, slightly curved gram-negative rods isolated from the gingival crevice of patients with gingivitis were studied. They seemed similar to Vibrio sputorum, though eleven strains differed in minor characters from Bergey's description under the new name Campylobacter sputorum,... | 821,391 | [
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Rickettsial cell water and membrane permeability determined by a micro space technique. | A micro space technique for determining membrane permeability in Rickettsia prowazeki is described and justified. The cell water, cell wall plus periplasmic volume, and glutamate, ethylene glycol, and adenosine diphosphate permeabilities were determined by this method. The effect of nonionic detergents on rickettsial p... | 821,395 | [
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Group D enterococcal meningitis. Clinical and therapeutic considerations with report of three cases and review of the literature. | Three patients with meningitis due to the Lancefield group D enterococci are described and the pertinent literature is reviewed. Anatomic central nervous system (CNS) defects, prior neurologic or neurosurgical interventions, group D enterococcal endocarditis, and urinary tract infection appear to be important predispos... | 821,410 | [
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[Selective coronary scintigraphy using labelled microspheres]. | Selective intracoronary injection of microspheres labelled with radioactive substances which emit gamma rays with different energy levels (Indium 113 m and Technetium 99 m) allows us to explore by scintigraphic methods the areas of distribution of the two coronary arteries. Having been carefully calibrated, the particl... | 821,414 | [
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... |
[Use of intra-aortic balloon in cardiac surgery]. | Use of the intra-aortic balloon in the treatment of circulatory failure after cardiac surgery has resulted in the long-term survival of 7 patients out of 20. The failures occured when the myocardium is severely compromised so that any treatment is likely to fait (8/13), and where there is the ultimate complication of r... | 821,419 | [
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[Temporary mechanical cardiocirculatory assistance in an adolescent suffering from subacute cardiac failure]. | A case is reported of subacute carciac failure during the course of a non-obstructive cardiomypathy in an adolescent. When the exacerbation of cardiac failure, which was accompanied by severe arrhythmias, failed to respond to medical treatment, the combination of a veno-arterial bypass and membrane oxygenator with dias... | 821,424 | [
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... |
[Atrial spetal defects of the ostium secundum type with mitral valve insufficiency. Apropos of 31 cases]. | 31 cases of ASD with mitral incompetence have been reviewed. The aetiology of the mitral incompetence is most frequently congenital, contrary to the classical view. The usual mitral defect is a combination of gaping of posterior commissure with a narrow valvular opening. The usual angiocardiographic picture is one of p... | 821,431 | [
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0.4900651,
0.02310775,
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[Association of progressive external ophthalmoplegia and myocardiopathy with complete atrioventricular block. Apropos of a new case]. | The authors report the case of a 31 year old man with an occulomotor palsy, who was admitted to hospital with complete atrio-ventricular block and syncopal attacks. The possible pathogenic significance of this association has given rise to differing hypotheses. A review of the literature shows that the occulomotor pals... | 821,446 | [
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0.2986827,
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0.1915018,
0.01253425,
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Chronic cerebellar stimulation in epilepsy. Clinical and anatomical studies. | Ten of 15 patients subjected to chronic cerebellar stimulation have had previously intractable seizures modified or inhibited up to periods of three years. Stimulation of anterior lobe appears to be more efficacious than stimulation of posterior lobe. Cerebellar biopsies, obtained in five patients at the time of stimul... | 821,458 | [
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Identiy of brain alcohol dehydrogenase with liver alcohol dehydrogenase. | A method for obtaining electrophoretically homogeneous rat liver alcohol dehydrogenase (EC 1.1.1.1) at a specific activity of 2-2.5 mumol/min per mg of protein is presented. Anti-sera prepared against the purified enzyme inhibit alcohol dehydrogenase by up to 75% and cause precipitation of virtually all the enzyme. The... | 821,468 | [
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[Distribution, absorption and elimination of radioactivity following oral and intravenous application of 2'-14C-labelled cyproterone acetate to rhesus monkeys (author's transl)]. | 13 female rhesus monkeys were given 2'-14C-cyproterone acetate i.v. and p.o. The radioactivity of the blood plasma and the elimination in urine and faeces were then measured at suitable intervals for a period of 12 days. After i.v. administration the time for distribution in the body amounted to 8 h. The extrapolated i... | 821,492 | [
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0.1453534,
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Messenger ribonucleic acid metabolism in mammalian mitochondria. Isolation and characterization of polyribosomes from Ehrlich ascites mitochondria. | The Mg2+ precipitation procedure of R. D. Palmiter ((1974) Biochemistry 13, 3606) has been used for preparative scale isolation of polysomes from Ehrlich ascites mitochondria. Digitonin-washed metochondria used for isolating the polysomes contain no detectable reduced nicotinamide adenine dinucleotide phosphate-cytochr... | 821,518 | [
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... |
[Role of metal ions in beef liver isocitrate dehydrogenase activity. Characterization of substrate forms]. | The enzymatic activity of cytoplasmic NADP linked isocitrate deshydrogenase is under control of divalent metal cations. Both forms of tribasic isocitrate, free and metal chelated are used as alternative substrates with different turnover and affinity. The esential role of the metal cation is to increase the affinity of... | 821,542 | [
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0.2400955,
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0... |
[Comparative assessment of the specific activity of several thyrotropin-releasing-hormone analogs]. | A study was made of the effect of replacement of the second and third amino acid residues of the thyrotropin-releasing hormone on the manifestation of the specific biological activity assessed by the radioimmune method of determination of the thyrotropic hormone in rats. Replacement of histidine by alanine caused a 100... | 821,571 | [
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... |
Diphosphonate therapy in nephrocalcinosis. | 4 patients with nephrocalcinosis were treated with disodium ethane 1-hydroxy-1, 1-diphosphonate (EHDP) for a period of 13 months. No clinical side-effects were observed and growth proceeded normally. Radiographic changes of osteitis fibrosa cystica developed in 1 child and bone biopsy in 2 children showed defective ost... | 821,572 | [
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The raphe nuclei of the cat brain stem: a topographical atlas of their efferent projections as revealed by autoradiography. | Stereotaxic injections of [14C]leucine were made in nulei raphe centralis superior, raphe dorsalis, raphe magnus and raphe pontis of the cat. The organization of the regional connections was outlined in a stereotaxic atlas using the autoradiographic tracing method: the majority of the ascending pathways from the rostra... | 821,589 | [
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Comparative pathology of Lassa virus infection in monkeys, guinea-pigs, and Mastomys natalensis. | Experimental Lassa virus infections of squirrel monkeys, guinea-pigs, and the African multimammate rat, Mastomys natalensis, were studied virologically and pathologically. In the monkeys, early viral lymphoreticulotropism, hepatotropism, nephrotropism, and viraemia were noted. At the time of death, viral titres in near... | 821,625 | [
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... |
[Role of phagocytosis and soluble antibacterial factors in experimental immunization of Locusta migratoria]. | Last instar larvae of Locusta migratoria can be protected ("vaccinated") against lethal doses of Bacillus thuringiensis by previous injections of low doses of this pathogen. If iron saccharate is injected in to larvae prior to the administration of the "vaccinating" dose of Bacillus thuringiensis, no antibacterial prot... | 821,627 | [
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[Development of gonads transplanted homoplastically in limbs of sexually immature axolotls]. | Graft development depends on sexual maturation of the host. Three successive steps in development of transplants have been demonstrated: somatic growth, gonial division and germinal maturation. Sexual maturity occurs earlier in females than in males. | 821,644 | [
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... |
[Structure variations of short polytene chromosomes in 2 pyrenean populations of Bilobella aurantiaca Caroli (Collemboles)]. | Structural variations of the short polytene chromosomes VI and VII occur in two Pyrenean populations of Bilobella aurantiaca. They are the result of longitudinal cleavage and also of variations in the number of the thin bands. They are not dependent on ecological factors, but often correlate with the chromosome polyten... | 821,653 | [
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[Induction of immune tolerance by free unreactive haptens]. | The injection of free non-reactive hapten, before immunization with the same hapten conjugated to one carrier protein, induces specific unresponsiveness to the hapten in Rats. Two haptens have been assayed: dinitrophenyl-Lysine and Arsonate-Tyrosine. In both cases, the Rats responded normally to the carrier but did not... | 821,657 | [
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... |
[Inhibition of the sodium inactivation of the nodal membrane by anemonia sulcata toxin II]. | A neurotoxin (ATX-II) extracted from the tentacles of Anemonia sulcata has been found to interact with the sodium channel of the nodal membrane in myelinated nerve fibres from Rana esculenta. If externally applied at low concentration (Kd = 20 muM), it reduces considerably the rate of inactivation of the sodium conduct... | 821,659 | [
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... |
[Action of broken fractions of regeneration blastema on the synthetic activity of posterior fragments or Dendrocelum lacteum cut behind the pharynx]. | Pounded blastemas of regeneration favour RNA synthesis is neoblasts of posterior parts of Dendrocoelum lacteum, cut behind the pharynx, which normally fail to regenerate a head; and induce excrescences. Fixed parenchyma cells and other differentiated tissues do not synthesize RNA with pounded blastemas. | 821,660 | [
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[Isopycnic centrifugation in metrizanide gradient of ribosomal ribonucleoprotein precursor particles]. | Metrizamide has been described as a new medium for isopycnic centrifugation of unfixed biological particles. In the murine leukemia cell line L 5178 Y, the buoyant density of 80 S and 60 S preribosomal particles was found to be 1,22 g/cm3, which is noticeably lighter than buoyant densities of mature ribosomal particles... | 821,661 | [
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0.... |
[X-ray effect on the moratility of ubescent subjects and female fertility in the amphipode crustacea Orchestia gammarellus (Pallas)]. | Orchestia gammarellus females and males were X-irradiated with doses of 2,300-40,000 R. The LD 50/20 is 2,300 R. No egg-laying was observed in any irradiated females. Radiosensitivity of embryos was higher than that of the female parent. | 821,668 | [
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0.4582886,
0.1398336,
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0.... |
[Differentiation of secretory tubes of avian kidney : effect of heterogenous inducers]. | In the chick embryo the nephrogenic blastema cells are determined before contact with the natural inductor (Wolffian duct or ureter) is established. In response to heterogeneous inductors, such as spinal cord or embryonic endoderm, the blastema cells differentiate into complete secretory tubules as shown by immunohisto... | 821,670 | [
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... |
[Isolation of 6 subunits of scorpion, Androctonus australis garzonii, hemocyanin]. | A method for the purification of the 5 sub-units 5 S and of a 7 S sub-unit of the haemocyanin of the Scorpion Androctonus australis garzonii is reported. It includes preparation of crude haemocyanin, dissociation in 1 M urea in the absence of divalent cations, starch gel electrophoresis and A 50 DEAE "Sephadex" separat... | 821,671 | [
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Use of laser nephelometry in the measurement of serum proteins. | Measurement of immunoglobulins (Ig) and of complement component C3 in human serum by automated and manual nephelometric techniques is tedious, and the effective linear range is too narrow. We describe a laser nephelometer/reagent system for measuring serum proteins by the use of forward light scatter (which enhances th... | 821,678 | [
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Three cases of GM1-gangliosidosis. | A biochemical analysis was carried out on three cases of GM1-gangliosidosis which showed different clinical manifestations. These cases were classified in a previous study as Type 1, Type 2 (2B) and Type 2 (2A), an intermediate type between classical Type 1 and Type 2 (2B), by the determination of the chromatographic p... | 821,679 | [
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Measurement of anticonvulsant activity in the Papio papio model of epilepsy. | The status of Papio papio as a model of clinical epilepsy has been reviewed. The anticonvulsant effects of single doses of various classic and experimental agents have been compared against seizures induced in the P. papio by intermittent light stimulation. Long-acting but not short-acting barbiturates have been shown ... | 821,787 | [
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0.16007... |
Pharmacokinetic evaluation of dosing regimens for insulin in diabetic ketoacidosis. | A pharmacokinetic model of the insulin-glucose system was used to examine the effectiveness of insulin administered by a variety of routes and regimens for diabetic ketoacidosis. The blood plasma concentration of glucose was set at 1,000 mg. per dl., and the effects of the following insulin regimens on the glucose plas... | 821,805 | [
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Field observation of a birth in hamadryas baboons. | A birth in hamadryas baboons was observed during an 18-month field study in Ethiopia. The behavior of the birth-giving female and the members of her harem unit are described. | 821,828 | [
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[Effect of amino acid infusions on fructose-induced chemical blood changes in intensive care patients]. | Influence of the infusion of amino acid solutions on metabolic changes caused by parenteral nutrition with fructose. In eleven unconscious polytraumatized patients of the intensive care station, intravenous infusions with fructose (0.5 g/kg bodyweight and hour) were performed. During the last 24 hours of the 72 hours i... | 821,861 | [
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Application of xeroradiography in sialography. | Sialography was carried out in healthy volunteers and in patients with Sjögren's syndrome. A comparison was made between xeroradiography and conventional radiography. Superior images were obtained with xeroradiography and this technique also tended to reveal glandular structure which was obscured by overlying bone when... | 821,870 | [
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Extraction of teeth with root preservation. | A method for covering single root-filled roots by mucosal flaps has been developed. The method has been used for patients attending the Royal Dental College, Copenhagen, for total extractions of teeth and full denture treatment. The operative method consists in covering a crown-resected, root-filled root by a combined ... | 821,873 | [
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... |
Comparative study of the balance and metabolic effect of post-operatively infused carbohydrates. | If glucose, fructose, and xylitol are infused in the immediate post-operative period at rates necessary for parenteral nutrition, all three substrates produce specific undersired effects. These effects can be reduced significantly when the three substrates are infused in the form of a mixture. The composition and the r... | 821,878 | [
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0.05614281,... |
Pyelonephritis. XIX. Immunization against enterococcal pyelonephritis. | A study has been done of immunization against Streptococcus faecalis pyelonephritis in the rat. Intravenous, subcutaneous, and bladder immunizations were tested with intravenous and retrograde challenge. Logarithmic and stationary growth phase organisms were used separately for both immunization and challenge. The only... | 821,898 | [
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Characterization of the N-acetylmuramic acid L-alanine amidase from Bacillus subtilis. | The N-acetylmuramic acid L-alanine amidase from Bacillus subtilis W-23 has been purified to apparent homogeneity. The enzyme is a monomer of molecular weight 51,000, which binds extremely tightly to homologous cell walls but not to heterologous cell walls, even of the closely related strain B. subtilis ATCC 6051. This ... | 821,918 | [
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Bacillus pumilus plasmid pPL10: properties and insertion into Bacillus subtilis 168 by transformation. | Bacillus pumilus ATCC 12140 harbors 10 or more copies per chromosome of each two small plasmids. Variants of this strain were isolated which were sensitive to a killing activity produced by the plasmid-containing parent. Each of 24 such sensitive (S) variants tested lacked detectable levels of supercoiled deoxyribonucl... | 821,919 | [
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Metabolism of 5-hydroxylysine in Pseudomonas fluorescens. | Hydroxylysine is metabolized via two routes by a Pseudomonas fluorescens strain as shown by the oxidation of selected intermediates. Hydroxy-L-lysine is oxidized via a pathway analogous to the monooxygenase pathway for L-lysine, and data suggest that at least some of tthe enzymes are those involved in the metabolism of... | 821,924 | [
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... |
Chemical and hemolytic properties of sphingolipids modified by ozonolysis and reduction. | Various sphingolipids were chemically modified in their sphingosine base by ozonolysis and reduction. The derivatives obtained from Forssman globoside, globoside I, galactosyl ceramide, and sphingomyelin were purified and all were found to be hemolytic. The presence of cholesterol could inhibit this activity. The simul... | 821,941 | [
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Characteristics of guanosine triphosphate cyclohydrolase I purified from Escherichia coli. | GTP cyclohydrolase I, an enzyme that catalyzes the first reaction in the pathway for the biosynthesis of the pteridine portion of folic acid, was purified from Escherichia coli by 3,900-fold to apparent homogeneity. Its molecular weight is estimated at 210,000. At relatively high concentrations of salt (e.g. 0.3 M KCl)... | 821,948 | [
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Escherichia coli tyrosine transfer ribonucleic acid genes. Nucleotide sequences of their promoters and of the regions adjoining C-C-A ends. | The template-dependent primer elongation method for determining DNA sequences of specific regions (e.g. Loewen, P., Sekiaya, T., and Khorana, H. G. (1974) J. Biol. Chem. 249, 217-226) has been applied to the determination of the sequences of the promoters and of the regions beyond the C-C-A ends of the tyrosine tRNA ge... | 821,949 | [
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Structure of ATP citrate lyase from rat liver. Physicochemical studies and proteolytic modification. | ATP citrate lyase was purified by two different procedures from the livers of rats first starved and then fed with a fat-deficient and high carbohydrate-glycerol diet. These enzyme preparations were judged homogeneous by sedimentation equilibrium and polyacrylamide gel electrophoresis. The molecular weight of the nativ... | 821,950 | [
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... |
The role of divalent cations in the regulation of microtubule assembly. In vivo studies on microtubules of the heliozoan axopodium using the ionophore A23187. | Low concentrations of calcium and magnesium ions have been shown to influence microtubule assembly in vitro. To test whether these cations also have an effect on microtubules in vivo, specimens of Actinosphaerium eichhorni were exposed to different concentrations of Ca++ and Mg++ and the divalent cation ionophore A2318... | 821,953 | [
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Artifactual seven-day cycles in spontaneous activity in wild rodents and squirrel monkeys. | Seven-day cycles in spontaneous activity were found in wild animals (recently trapped Norway rats, chipmunks, ground squirrels, and squirrel monkeys), but not in tame domesticated animals (laboratory Norway rats and hamsters). This 7-day cycle turned out to be a function of emotional reaction of the wild animals to hit... | 821,978 | [
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Effect of vestibular deafferentation upon positional nystagmus in the squirrel monkey. | Seventeen of eighteen squirrel monkeys, under a restrained condition, showed positional nystagmus in different body positions. Good repeatability and consistency of the nystagmus were found, especially at the left-lateral, right-lateral, and head-hanging positions. Positional nystagmus was not observed after the subjec... | 822,111 | [
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B-lymphocyte heterogeneity: ontogenetic development and organ distribution of B-lymphocyte populations defined by their density of surface immunoglobulin. | The density of total Ig and of IgM, IgG1, IgG2, and IgA on the surface of adult murine splenic B lymphocytes was measured using the technique of rapid flow microfluorometry. In addition, the density of total surface Ig and of IgM on B lymphocytes derived from adult bone marrow, lymph nodes, and Peyer's patches, and fro... | 822,116 | [
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... |
Mast cells in benign nerve sheath tumours. | The concentration of mast cells was estimated, and their distribution noted, in 132 benign nerve sheath tumours. With few exceptions, neurofibromas were characterised by a high concentration of diffusely distributed mast cells. In neurilemmomas fewer mast cells were present and these were restricted to Antoni type-B ti... | 822,142 | [
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Leucocytozoon maccluri sp. n. (Haemosphorida: Leucocytozoidae) from a Thailand thrush, Zoothera marginata Blyth. | A new species of Leucocytozoon with elongate gametocytes and unique morphology is described from a Thailand thrush, Zoothera marginata, and represents the first fusiform leucocytozoid named from a passeriform. This species appears to be restricted with respect to geography and host. | 822,146 | [
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Conditional mutations in the translational apparatus of Bacillus subtils. | Four temperature sensitive mutants of B. subtilis were isolated by localized mutagenesis in the major ribosomal gene cluster, and charcterized genetically and biochemically. Three are mutations which cause temperature sensitivity in the elongation factor Ef-G, and one which has a similar effect on the elongation factor... | 822,278 | [
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[Continuous local application of cytostatics for bronchial carcinoma and mediastinal lymph node metastasisization (author's transl)]. | A carcinostatic substance (5-fluorouracil) was instilled into the mediastinal lymph nodes, the pleural cavity or the internal thoracic artery by continuous perfusion before operation on patients with bronchial carcinoma. Degenerative changes could be demonstrated histologically in the cancer cells in the lymph node met... | 822,285 | [
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-0.008670698,
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[Concomitant depressions in non-psychiatric diseases. Identification and therapy of depressive components]. | We introduce the new term "concomitant depression" and define it purely phenomenologically as the simultaneous appearance of a depressive mood and physical disease. Its place within the framework of previously current nomenclatures and classification according to causal principles are discussed. Neurology and internal ... | 822,287 | [
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0.2487386,
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0.2717242,
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0.04657467,
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0.3511941,
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0.2343132,
0.05229266,
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0.06580923,
0... |
[Polyacrylic bone cement with added erythromycin and colistin. In vitro studies on bacteriologic activity and diffusion properties]. | Erythromycin and colistin are not antagonists and have the property of inhibiting the growth of a large number of aerobic and anaerobic organisms. When they were worked into Chirurgischen Knochenzement Simplex P Radiopaque, the growth of 98% of all anaerobic and aerobic test organisms was inhibited. Separately conducte... | 822,289 | [
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0.4225109,
0.4703578,
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0.401122,
0.20... |
[Chemotherapy and chemoprophylaxis of malaria (author's transl)]. | Chloroquine and amodiaquine are demonstrably still the most reliable drugs for the treatment of malaria, except in the south east Asia area, and in parts of south and central America where an altered sensitivity of falciparum plasmodia has been confirmed. The present position of malaria prophylaxis is, unfortunately, a... | 822,313 | [
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0.2161268,
0.07532448,
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0.360277,
0.2837741,
0.02270675,
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0.0... |
Mutangenicity and toxicity of amitrole. I. Drosophila tests. | Amitrole was highly toxic at early larval stages of Drosophila (LD50 is 40 ppm in medium). Toxicity of amitrole was also revealed by prolongation of development time even at 10 ppm. However, no mutagenic effects of amitrole were observed either in the sex chromosome non-disjunction test (females reared on medium contai... | 822,329 | [
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0.3932574,
0.08169956,
0.2098701... |
Simultaneous occurrence of IgG3-kappa and IgG2-lambda paraproteins in a 12-year-old girl with malignant reticulosis. | Transient occurrence of IgG3-kappa and IgG2-lambda paraproteins in a 12-year-old girl with malignant reticulosis is reported. These paraproteins were demonstrated in a total amount of 3.4 g/100 ml after termination of cytostatic treatment; they disappeared after another 2 months. | 822,361 | [
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... |
[Laser trabeculopuncture. III Experiments with rhesus monkeys]. | Argon-laser trabeculopuncture was carried out on 7 rhesus monkeys. Perforation of the trabecular meshwork was possible with laser impacts of 100 msec, 4,200 mW and a beam diameter of 50 mum. Clinical and histological observations covered an interval of up to 15 weeks after coagulation. They revealed an obliteration of ... | 822,382 | [
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0.06246493,
0.05189879,
0.3222395,
0.09546766,
-0.0580963... |
Total and free thyroxine in patients with liver cirrhosis. | In 11 patients with compensated and 10 with decompensated liver cirrhosis the following determinations were carried out: total thyroxine serum concentration (T4), triiodothyronine-binding coefficient (T3BC), free thyroxine by the dialysis method (DFT4), free thyroxine index (FT4I) and absolute value of free thyroxine (... | 822,399 | [
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0.05675804,
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0.192919,
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0.06457959,
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0.3331276,
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0.06... |
[Precipitation and prevention of abstinence in acutely morphinized rats and mice: comparisons between naloxone, naltrexone, and diprenorphine (author's transl)]. | Abstinence signs were precipitated in rats by naloxone (1 mg - kg-1 s.c.) injected at various times (from 1.5 to 16 h) after a single dose of morphine hydrochloride (15 or 50 mg - kg-1 s.c.) administered in aqueous solution. Increasing the dose of morphine increased the latency of the phenomena and the duration of the ... | 822,446 | [
0.177822,
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0.2231795,
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0.1219341,
0.4232899,
0.3012692,
0.1194899,
0.004818084,
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... |
[The metabolic basis of generalized skeletal dysplasia (author's transl)]. | Numerous control systems are involved in the growth and differentiation of chondro-osseous tissue. Theoretically, the failure of each single step will result in a peculiar skeletal dysplasia. The resulting disorders are caused by errors in the metabolism of collagen, minerals, complex carbohydrates and the protein of t... | 822,473 | [
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0.1205536,
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0.09136218,
0.5603353,
0.07553809,
-0.16... |
Estrogen-induced luteolysis in the rhesus monkey: reversal with indomethacin. | Normally cycling Rhesus monkeys were treated with diethylstilbestrol (25 mg/day) alone or in combination with indomethacin (25 mg/day) for five consecutive days beginning in the early luteal and mid-luteal phase of the menstrual cycle. Blood specimens were obtained daily to monitor corpus luteum function (progesterone)... | 822,478 | [
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0.03516559,
0.1931398,
0.3658208,
0.04060125,
... |
Amine-responsive adenylate cyclase activity from brain: comparisons between rat and rhesus monkey and demonstration of dopamine-stimulated adenylate cyclase in monkey neocortex. | The effects of biogenic amines on adenylate cyclase from rhesus monkey brain have been surveyed. Dopamine-responsive cyclase activity was found throughout the subcortical limbic area and limbic cortex, as well as in the sensorimotor cortex, where stimulation by dopamine was blocked by fluphenazine. Cyclase activity fro... | 822,479 | [
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0.3129019,
0.1891673,
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... |
Metabolic reduction of naltrexone II. In vitro studies using liver from guinea pig, monkey and rat. | Naltrexone was incubated with the 9000 X g supernatant of guinea pig liver in the presence of an NADPH-generating system to determine the relative amounts of the 6-keto reduction products, alpha- and beta-naltrexol, formed in vitro. After a 0.5-2 hour period both alpha- and beta-naltrexol were formed as detected by ele... | 822,483 | [
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0.4208188,
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0... |
[Experience with e new water soluble contrast medium for lumbar myelography (author's transl)]. | Meglumin-Iodrinat has been synthesized as the contrasting part of Myelografin by Schering AG. and tested for lumbar Myelography in animal experiments. The excellent neural and general compatibility justified a first clinical trial. 200 patients were examined, 100 each with following upright or lying down positions. The... | 822,502 | [
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0.2463469,
-0.002865304,
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0.07657478,
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0.3459069,
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0.06515991,
-0.13151,
0.5248436,
-0.05486668,
0.001175833,
0.018666... |
Hyperlipidemia and atherosclerosis. | These studies provide new insight into the complex mechanisms wherby hyperlipidemia causes progressive atherosclerosis. It has been shown that physical injury to the endothelial lining of arteries sets off a process which probably is an attempt at healing the injury but which can lead to atherosclerosis. It has also be... | 822,515 | [
-0.06513267,
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-0.03467459,
0.03328946,
0.08301587,
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0.1479792,
0.1849023,
0.1957754,
0.2001641,
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0.1435644,
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-0.08635082,
-0.2829728,
0.1691298,
-0.1685091,
0.1913839,
-0.023... |
[Coccidia and coccidiosis in the rock partridge, Alectoris graeca cypriates. I. Coccidian species, systematics and morphological characteristics and the seasonal and age-related dynamics]. | A total of 6,375 samples were taken from rock partridges of the Alektoris graeca cypriates species. Coccidia were found in 1,437 of them. In forty-three per cent of the cases the parasites belonged to Eimeria kofoidi, in 29.2 per cent--to E. procera, in 12 per cent--to E. cotornicis, in 6.9 per cent--to E. phasiani, an... | 822,568 | [
-0.1235048,
0.3022158,
0.1824522,
0.1381848,
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-0.2307882,
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0.01036538,
0.01823102,
0.132197,
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0.1150836,
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0.2366777,
0.400711,
0.3873099,
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0... |
Complement-mediated acinar cell necroses in pancreatitis induced by basement membrane antibodies. | To study the role of the serum complement system in the early necrosis of acinar cells an acute pancreatitis was produced by injection of basement membrane antibodies into the pancreatic duct of mice and rats. In all animals deposition of complement (C3) and antibasement membrane IgG could be observed in an identical p... | 822,574 | [
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0.1199614,
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0.2025868,
0.1351029,
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0.3311529,
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0.01811366,
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0.04226482,
0.05327799,
0.1012363,
0.1206816,
0.02628356,... |
Delayed dermal hypersensitivity in rhesus monkeys (Macaca mulatta) immunized against Plasmodium knowlesi. | Eighteen Rhesus monkeys were immunized with a fresh or lyophilized antigen preparation obtained from erythrocytes infected with Plasmodium knowlesi. Sixteen of these monkeys showed a positive delayed hypersensitivity response when subsequently skin tested with the immunizing antigen. Ten of the 16 positive reactors sur... | 822,621 | [
0.1053466,
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0.2033218,
0.2243293,
0.1161501,
0.0776227... |
[Findings concerning characteristics of responses to administration of vaccines containing antigenic complexes of enteric bacteria and tetanus toxoid]. | Forty eight hours after the immunization with vaccines containing antigenic complexes of typhoid-paratyphoid and dysentery bacteria (0.65--1 mg of the antigens per vaccination dose) some of the persons vaccinated displayed an increase in the leukocyte count chiefly on account of the neutrophil forms and monocytes, a mo... | 822,656 | [
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0.1377654,
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0.2078051,
-0.1227277,
... |
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