title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Preferential cytotoxicity of 5-thio-D-glucose against hypoxic tumor cells. | 5-Thio-D-glucose effectively killed hypoxic mastocytoma cells of DBA/2J mice, whereas it merely suppressed the growth of oxic cells. This specific toxicity suggested that 5-thio-D-glucose may be a useful adjuvant to radiotherapy by eliminating hypoxic protection. | 824,455 | [
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Semliki Forest virus capsid protein associates with the 60S ribosomal subunit in infected cells. | Semlike forest virus capsid protein cosedimented with the large ribosomal subunit at 60S in sucrose gradients after treatment of cytoplasm from infected cells with Triton X-100 and EDTA. In CsCl gradients the capsid protein banded with the subunit at a density of 1.56 to 1.57 g/cm3. Most of the capsid protein could be ... | 824,460 | [
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Mucoid Pseudomonas aeruginosa. A sign of cystic fibrosis in young adults with chronic pulmonary disease? | Two adult patients with cystic fibrosis had late onset of symptoms with principal involvement only of the lungs. The absence of other typical features of cystic fibrosis confused the diagnosis. Recovery of mucoid Pseudomonas aeruginosa from sputum cultures helped to establish the diagnosis in these patients, because th... | 824,466 | [
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[Combined ulcers of the stomach and duodenum (author's transl)]. | The simultaneous appearance of a gastric ulcer with a duodenal ulcer or postulcerous changes is primarily caused by a duodenal ulcer. A gastric ulcer may occur secondarily; the possible causes of this development are discussed. | 824,550 | [
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Oxygen consumption of the isolated carotid body tissue (cat). | The oxygen consumption of the isolated carotid body tissue measured in microchambers (volumes 12 and 20 mul) was 0.0051 mul O2/mg wet weight-min for an average of 54 measurements at 22 +/- 1 degree C, if the calculation was based on the oxygen pressure decrease of the surrounding medium measured polarographically in th... | 824,612 | [
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[Treatment of diabetic keto-acidosis through continuous insulin infusion]. | Presented are results obtained with a continuous intravenous infusion of regular insulin in 13 cases of diabetic ketoacidosis. A bolus of 10 units of insulin followed by an average of 15 units delivered via an infusion pomp induce an immediate and regular decrease of blood glucose levels (1.63 +/- 0.15 g/h). A large qu... | 824,621 | [
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Nontraditional graduate training for administrators of neighborhood health centers. | Because of the shortage of qualified health care administrators who are members of minority groups, many neighborhood health centers, organized as a result of the Great Society legislation of the 1960's, suffered from their staffs' lack of administrative skills and from rapid turnover as staff members gained experience... | 824,670 | [
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Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. | Prostaglandin (PG) endoperoxides (PGG2 and PGH2) contract arterial smooth muscle and cause platelet aggregation. Microsomes from pig aorta, pig mesenteric arteries, rabbit aorta and rat stomach fundus enzymically transform PG endoperoxides to an unstable product (PGX) which relaxes arterial strips and prevents platelet... | 824,685 | [
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[Purification of purine nucleoside phosphorylase activity on deoxyinosine (author's transl)]. | Purified preparations of pigeon liver PNPase (E.C. 2.4.2.1) have been obtained by acid preparation of liver homogenates at pH = 5,followed by a fractionation with ammonium sulphate (25-50% saturation) and by a chromatographic adsorption on DEAE-cellulose. The preparation obtained shows a PNPase specific activity 325 ti... | 824,697 | [
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The passage of 14C-delta-9-tetrahydrocannabinol into the milk of lactating squirrel monkeys. | Lactating squirrel monkeys chronically receiving 2 mg/kg delta-9-tetrahydrocannabinol (THC) orally either two or five times weekly were given a tracer dose of 14C-delta-9-THC mixed with the delta-9-THC. This permitted radioquantitation of the THC in milk specimens collected 1 to 24 hr after administration of the labele... | 824,699 | [
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[Fabry's disease (angiokeratoma corporis diffusum universale): benign course after kidney transplantation]. | A case of Fabry's disease in a 52-year-old man is reported. At the age of 45 the patient developed uremia, and nephrectomy and kidney transplantation were performed. The follow-up is described and compared to other published cases. Up to now no single therapy is known, but kidney transplantation appears to be justified... | 824,727 | [
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Activating factor for the iron protein of nitrogenase from Rhodospirillum rubrum. | As isolated from Rhodospirillum rubrum, the iron protein of nitrogenase has little or no activity. It can be activated by incubating it with a trypsin-sensitive, oxygen-labile component (activating factor) plus adenosine triphosphate and a divalent metal ion. After activation, the iron protein retains its nitrogenase a... | 824,729 | [
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Primate flicker sensitivity: psychophysics and electrophysiology. | A quantitative comparison is made between the psychophysical flicker response of man and similar data obtained electrophysiologically from the cones of macaque monkeys. When the psychophysical data are obtained from an eye that is strongly light-adapted, there is excellent agreement between the two sets of data at high... | 824,735 | [
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Juvenile polyposis coli concurrent with neurofibromatosis. | Juvenile polyposis coli associated with neurofibromatosis in a 24-year-old white man is reported. Juvenile polyposis coli is now recognized as a distinct clinical entity. Differentiating it from the other hereditable gastrointestinal polyposis syndromes is important because of the lack of reported malignancies. Radical... | 824,744 | [
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Skin lesions during intravenous hyperalimentation: zinc deficiency. | Of 54 patients who received prolonged intravenous hyperalimentation during the past 4 years, six developed progressive, characteristic skin lesions. These cutaneous manifestations frequently were accompained by abdominal symptoms resembling those of acrodermatitis enteropathica in many respects. In the first four of th... | 824,754 | [
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[Comparative studies on the immunodiagnosis of filariasis (author's transl)]. | Four serological methods have been evaluated for the immunodiagnosis of filarial infections in European patients returning from endemic areas. The highest sensitivity was found by the immunoelectrophoresis (73%), followed by the indirect fluorescence antibody test (60%) and the indirect hemagglutination (57%). The reli... | 824,773 | [
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[Fixed acids during the traditional cesarean section in cows]. | The values of lactic acid, pyruvic acid and L/P index were studied in cows at the traditional Caesarean section. The values of the mentioned metabolites are presented in dependence on the intensity and length of parturient activity that are affected by the anesthesia applied during surgical procedures. An increase of t... | 824,786 | [
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[Results of bacteriological and cytological studies of uterine lavages in cows from herds with fertility disorders]. | A cytological and bacteriological examination of uterine lavages of 264 cows from herds with fertility disorders (without convincing pathological findings) helped to determine the clinical diagnosis in a more exact way. In 41.67% of the cases, mucosal metritis was cytologically proved. Bacterial contamination of the ur... | 824,789 | [
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[Central giant cell granuloma. Histochemical and ultrastructural study on giant cell function (author's transl)]. | Multinucleated giant cells in giant cell granuloma are formed by cell fusion of capillary pericytes. In our present study we tried to analyze cell function and activity by histologic, histochemical, and electronmicroscopic examination of giant cells. Lysosomal enzymes such as acid phosphatase and amino-peptidase were f... | 824,799 | [
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Atoxyl-induced damage to the sensory cells in the organ of Corti in the guinea pig cochlea. | Atoxyl-induced damage to the inner and the outer hair cells in the guinea pig cochlea starts in the apical coil and spreads successively downward toward the round window. Vesicular degeneration of both the inner and the outer hair cells and the cell organelles occurs. The degeneration is probably caused by an alteratio... | 824,808 | [
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[Investigations on the development of volatile substances during lipoxygenase-linolic-acid-reaction (author's transl)]. | During incubation of soja-lipoxygenase with linolic acid, volatile compounds are formed the development of which can be seen in two possible ways:from preformed linolic-acid-hydroperoxides splitproducts arise or volatile substances of different chemical nature are built depending on the reaction conditions like tempera... | 824,883 | [
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B.C.P. Jansen Institute, University of Amsterdam, Amsterdam, The Netherlands. | In a patient with Fabry's disease who had undergone kidney transplantation to correct uremia, the neutral glycosphingolipids and alpha-galactosidase activity have been measured in plasma and urine and, 9 months later, after the death of the patient, in autopsy material. After transplantation, there was no significant i... | 824,932 | [
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Renal prostaglandins. | 1. Renal prostaglandins act primarily as local hormones, having their effects at, or near to, sites of synthesis. PGE2 is a major determinant of renal vascular reactivity; it opposes the vasoconstrictor and natriuretic actions of pressor hormones and brakes the release of noradrenaline from adrenergic nerves. In the un... | 824,936 | [
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Estimation of tissue protein synthesis in rats fed diets labeled with (U-14C)tyrosine. | The rate of liver and muscle protein synthesis has been measured in 27 rats after feeding L-[U-14C]tyrosine in L-amino acid diets prepared as agar gels. Constant specific activity of the free tyrosine pool, as indicated by constant excretion of 14CO2, was reached within 2 h of feeding and was maintained for the remaini... | 824,957 | [
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Additive inhibition of renal bicarbonate reabsorption by maleate plus acetazolamide. | The effects of two potent inhibitors of renal bicarbonate reabsorption--maleate and acetazolamide--were investigated in the rat using clearance techniques. Acetazolamide given in high dose (50 mg/kg body wt) inhibited fractional bicarbonate reabsorption by ca. 30%, maleate (2.58 nmol/kg body wt) by 25%, and maleate plu... | 824,958 | [
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[Development of resistance in Pharaoh's ant (Monomorium pharaonis)]. | The possibility of resistance development in the pharaoh's ant Monomorium pharaonis in regard to insecticides and chemosterilants in general and in the special case of sodium arsenate is discussed. The low number of sexuals and the long duration of generations reduced the possibility of the development of resistance in... | 824,978 | [
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[Simple and rapid technic of grouping of streptococci]. | The authors propose a simple and rapid technique of grouping of streptococci. Streptococcal extracts were obtained by the action of nitrous acid at laboratory temperature. Serogrouping was carried out by electro-immunodiffusion. A study was made of 200 strains of hospital origin. The qualities of specificity and sensit... | 824,983 | [
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Dermatophilosis in a titi monkey (Callicebus moloch). | The occurrence of dermatophilosis in the titi monkey is reported. Lesions were principally in the epidermis of the skin and were characterized by parakeratosis, necrosis, abscess formation, acanthosis, and hyperkeratosis. The cause, Dermatophilus congolensis, was demonstrated as a gram-positive filamentous organism wit... | 824,984 | [
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0.15... |
[Protein and energy value of spiruline blue algae supplemented by amino acids: digestive and metabolic utilization by the growing rat]. | Protein and energy value of 6 samples of "Spirulina" was studied on growing rats in 1972 and 1973. Sample RL 1(Spirulina platensis, originating from Tchad) was grown in artifical conditions in a laboratory. Others samples (Spirulina maxima) were grown in the solar evaporator near Mexico, washed and dried either on heat... | 824,996 | [
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[Incorporation of a spiruline (Spirulina maxima) in swine food]. | Two experiments on early weaned piglets and one experiment on sows during the first two reproductive cycles were made to determine the nutritive value of Spirulina maxima algae in the pig, taken as a "nutritional model" for man. The algae were introduced into the diets of the piglets, between 12 and 42 days of age, in ... | 825,004 | [
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[Intracellular glycosaminoglycans of diploid and heteroploid human cells and of hybrid cell lines issued from their fusion]. | The human heteroploid cell line D98/AH-2 shows a low level of glycosaminoglycans (GAG) synthesis as compared with normal human diploid fibroblasts. Cellular hybrids were obtained by fusion of the D98/AH-2 cell line with normal fibroblasts, and fibroblasts derived from patients with mucopolysaccharidosis type II. In the... | 825,015 | [
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[Hepatocystis of Malaysia. II.--Description of Hepatocystis brayi n. sp. parasite of Sciuridae (author's transl)]. | Hepatocystis brayi n. sp. is described and separated from the second species parasitising Malaysian Sciuridae, H. malayensis Field and Edeson, 1950. H. brayi is characterized by: 1) the evolution of its tissue schizonts which are intracellular throughout all their development; the cytoplasm and the nucleus of the host ... | 825,009 | [
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Comparative activity of netilmicin, gentamicin, amikacin, and tobramycin against Pseudomonas aeruginosa and Enterobacteriaceae. | Netilmicin (Sch 20569), a semisynthetic aminoglycoside antibiotic, was compared with gentamicin, tobramycin, and amikacin against 242 clinical isolates of Pseudomonas and Enterobacteriaceae. The minimum inhibitory concentration (MIC) was determined in both solid and liquid media. Netilmicin exhibited typical aminoglyco... | 825,032 | [
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Ferric iron reduction by sulfur- and iron-oxidizing bacteria. | Acidophilic bacteria of the genera Thiobacillus and Sulfolobus are able to reduce ferric iron when growing on elemental sulfur as an energy source. It has been previously thought that ferric iron serves as a nonbiological oxidant in the formation of acid mine drainage and in the leaching of ores, but these results sugg... | 825,043 | [
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[Pathogenesis of arrhythmias in acute myocardial infarction]. | Over the last few years, much experimental work has been done to try and elucidate the pathogenesis of disorders of rhythm in myocardial infarction. The role of bradycardia during the first few hours has been discussed, and the use of atropine has been criticised. Some light has been thrown on the importance of the Pur... | 825,058 | [
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[Echocardiographical study of 2 cases of aortic dissection]. | The authors report two cases of acute dissection of the ascending aorta and aortic arch. An urgent ultrasonic investigations showed, in both cases, signs of reduplication of the parietal image, which is highly suggestive of the condition; this was confirmed by angiography. These two cases enable us to discuss the crite... | 825,060 | [
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[Myocardial infarction: comparative study of principal risk factors in the two sexes]. | A study of the distribution of the various risk factors for coronary artery disease as a function of the age and sex of a homogenous population of 316 patients has brought to light the following findings: -- These was found to be a greater incidence (statistically significant) of hypertension disorders of glucose metab... | 825,069 | [
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Comments on the translational and transcriptional origin of Euglena chloroplastic aminoacyl-tRNA synthetases. | A response to: "A consideration of Euglena gracilis W3BUL as a cytoplasmic control for the wild-type phenylalanyl-tRNA synthetase system" and "A reinvestigation of the sites of transcription and translation of Euglena chloroplastic phenylalanyl-tRNA synthetase" by J. L. Lesiewicz and D. S. Herson. | 825,072 | [
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Structural transformation of the phagosomal membrane in Tetrahymena cells endocytosing latex beads. | A model system with a high phagosomal membrane turnover has been developed: During a 45-min period Tetrahymena cells endocytoze 186 latex beads (diameter: 2.02 mum) per average cell; 166 of these beads are then exocytozed in the course of the following 145 min. During the endocytotic phase an average cell is approximat... | 825,073 | [
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Behavior genetics of olfactory responses in Drosophila. I. Olfactometry and strain differences in Drosophila melanogaster. | A simple olfactometer was constructed for measuring the responses of adult Drosophila to odoriferous substances, and an index (attractability index, AI) is proposed to evaluate the response. Five strains of Drosophila melanogaster of different geographic origins were tested for their responses to five chemical attracta... | 825,093 | [
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The properties of uridine diphosphate glucuronyltransferase(s) which catalyse the synthesis of steroid glucuronides in microsomal fractions from guinea-pig liver. | The properties of the UDP-glucuronyltransferase(s) of guinea-pig liver that catalyse the synthesis of steroid glucuronides were examined. There are many similarities between apparently different substrate-specific forms of these enzymes in that all are activated by bivalent metal ions, and all contain at least 2 thiol ... | 825,111 | [
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Continuous Proteolysis with a stabilized stabilized protease. I. Chemical stabilization of an alkaline protease. | Due to the loss of enzymatic activity as a function of time, an alkaline protease, selected for the continuous preparation of protein hydrolysates (J. Boudrant and C. Cheftel, Biotechnol. Bioeng., 18,1735, 1976), was chemically stabilized by a simple treatment with glutaraldehyde. Two fractions, soluble and insoluble, ... | 825,155 | [
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Human tumors studied with genetic markers. | Genetic marker systems have been employed to investigate the origin and development of many human tumors. The type of information already gained with such systems includes the probable single cell origin of chronic myelocytic leukemia in a marrow stem cell. The G-6-PD system has also confirmed the hypothesis that at le... | 825,156 | [
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Nutritional situation in the world. | The paper describes the international nutrition problem, with references to previous crisis in the world. It is stated that the present situation cannot be compared to the historical famines in the past. The causes and magnitude of the problem are quite different. The information available on the nutritional situation ... | 825,168 | [
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Serum antibody in patients with prostatic cancer. | 130 serum specimens were evaluated. None of 24 serum specimens from patients with prostatic cancer yielded precipitation of haemagglutination reactions with extracts of normal human prostatic tissue or with preparations of prostatic fluid. In 1 of 5 patients from whom autologous prostatic tissue was available, precipit... | 825,178 | [
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The development of motor control in the rhesus monkey: evidence concerning the role of corticomotoneuronal connections. | Corticospinal fibres terminate in three areas in the spinal grey matter of the rhesus monkey: the nucleus proprius of the dorsal horn, the intermediate zone and directly upon motoneurons, particularly those inervating limb muscles. It was suggested at their earliest discovery that direct corticomotoneuronal (CM) connec... | 825,185 | [
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Microelectrode mapping of modality-specific somatic sensory cerebral neocortex in slow loris. | Microelectrode mapping methods and strategies were developed to map fine details of the somatotopic organization of somatic sensory cortex (SI) in slow loris. In-depth, multiple-unit recording, and threshold natural stimulation of skin and hari revealed three modality-specific cortical areas. The centrally located one ... | 825,191 | [
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[Electrosyneresis in the diagnosis of African trypanosomiasis]. | Comparative studies were carried out on serums from rabbits inoculated with several Trypanosoma strains and 50 serums from sleeping sickness cases. The techniques used were antigen-antibody reaction in gel according to Ouchterlony, and electrosynerese for which directions are outlined. Electrosynerese has been shown to... | 825,237 | [
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[Organ specific embryonic antigens during the differentiation of the liver and kidney in chickens]. | Among the cellular antigens, demonstrated by their reaction with Rabbit anti-embryonic Chick liver serum, two are present in the supernatant fraction obtained after ultracentrifugation of liver extracts from 6-day-old Chick embryos, and in the sedimentable fraction from the 9th day onward. A third antigen, detectable f... | 825,261 | [
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[In vitro study of the cytotoxic activity of sipunculid leukocytes towards allogeneic and xenogenic erythrocytes]. | A cell mediated cytotoxic reaction analogous to that known in Vertebrates is induced in vitro by leukocytes of sipunculid worms (coelomata invertebrates). Xenogenic or allogenic erythrocytes are employed as target cells. A cytotoxic effect always occurs when killer leukocytes react against xenogenic cells. A cytotoxic ... | 825,267 | [
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[Radiorestoration by 3 cytokinins contained in yeast RNAs and extracts, of scorzonera tumor tissues exposed to cobalt-60 gamma rays]. | The 3 natural cytokinins contained both in the extracts and RNA of yeast and the tumor tissues cultivated in vitro, elicit radiorestorative properties from the crown-gall tissues of Scorsonera submitted to Co60 gamma-rays. However the cytokinins produce no stimulating effect whatsoever on the non irradiated tissues tha... | 825,274 | [
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[Arrangement and local epidermal cell populations of Carcinus maenas (Crustacea, Decapoda)]. | Surface cuticular differentiations of normal and specialized cells of Carcinus maenas carapace have been observed with a scanning electron microscope. The appearance and polarity of the normal structures happen to be modified in the neighbourhood of the populations of specialized cells. An association of sensory and gl... | 825,278 | [
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[Inhibition of mouse-killing behavior by rats with taurine, GABA, and its analogues]. | The injection of Gaba, of taurine or of a structural analog of GABA (n-dipropylacetate) in the olfactive bulb of "killer" Rats was found to inhibit the mouse-killing behaviour of the rat. The same effect was obtained when taurine or n-dipropylacetate (which increases GABA in the central nervous system), was injected in... | 825,280 | [
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[Analysis of biospecific complexes by electrophoresis: antibiotics specific to bacterial ribosomes]. | Electrophoresis is a widespread method in biochemistry. Apparently it has never been used in the study of interactions found in enzyme-substrates or drug-receptor complexes. The aim of this Note is to describe some possibilities given by this simple technique especially in the case of interactions found between some an... | 825,305 | [
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[The byssus of Mytilus: electrophoresis of hydroxyproline-rich proteins from the "collagen gland"]. | An hydroxyproline rich fraction has been extracted from the byssus gland of Mytilus. This fraction could be the intracellular precursor of the "secreted collagen" found in the byssus threads. Its molecular weight, estimated through SDS gel electrophoresis, appears lower than that of a chains of mesenchymal collagen. | 825,306 | [
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-0.218897... |
[Simulation of polluted atmospheres for animal experimentation: toxic gases]. | A process for the generation of standardized polluted atmospheres usable for animal exposure is described. It is based on the diffusion of compressed gases across a silicone membrane. This device has been tested with four gases of particular importance in the field of atmospheric pollution (sulfur dioxide, nitrogen oxi... | 825,307 | [
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0.1... |
[Proton isoshielding curves of several nucleic acid intercalating agents]. | Intermolecular nuclear shielding values for protons, due to the ring-current effect, are computed for a plane parallel to and 3.4 A above the phenoxazone ring of actinomycin, ethidium, proflavin and quinacrine. | 825,316 | [
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[The effect of prostaglandin E2 (PgE2) on the uptake of noradrenaline (NA) by the isolated rabbit heart]. | Influence of the inhibiting action of PgE2 on the captation of NA by isolated Rabbit heart at a concentration of 1 X 10(-4)M, although its action on extraneuronal captation is already apparent at 1 X 10(-8)M. | 825,320 | [
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N-terminal amino acid sequence of a human delta-chain myeloma protein. | The N-terminal amino acid sequence (26 residues) of a delta-chain of a human myeloma (Er I) is homologous with the prototype sequence of the human VHIII subgroup. This indicates that the delta-chain is using for its V region the same pool of V genes as the rest of the immunoglobulin classes. Implications of this findin... | 825,370 | [
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... |
Distribution of thyrotropin-releasing hormone (TRH) in the central nervous system as revealed with immunohistochemistry. | With the indirect immunofluorescence technique TRH-containing nerve terminals were found in the medial part of the external layer of the median eminence, the dorsomedial nucleus and the perifornical area, in extrahypothalmic nuclei such as nucleus accumbens, the lateral septal nucleus and in several motor nuclei of the... | 825,379 | [
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[Consumption coagulopathy and acidosis in the diabetic patient (author's transl)]. | Four cases of intravascular coagulation associated with a state of acidosis in diabetics were observed in 57 patients with diabetic acidosis and 19 with lactic acidosis, in a series of 112 cases of consumption coagulopathy admitted to a department of medical resuscitation. In three cases the coagulopathy was found only... | 825,399 | [
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Peristalsis in smooth muscle esophagus after transection and bolus deviation. | The importance of the continuity of the muscle coat and of the presence of an intraluminal bolus for the peristaltic performance of the Rhesus monkey esophagus was studied. Transection and reanastomosis with muscle-to-muscle contact in the striated muscle part of the esophagus did not interfere with the progression of ... | 825,409 | [
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Regulation and biosynthesis of secondary metabolites. XVIII. Adenylate level and chlorotetracycline production in Streptomyces aureofaciens. | The relationship was studied between the energy metabolism of the actinomycete Streptomyces aureofaciens and the biosynthesis of chlorotetracycline by this organism. The energy charge values in a culture of low-production strain were almost identical with those of a production variant but the total sum of adenylates wa... | 825,418 | [
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Initial colonization of teeth in monkeys as related to diet. | The initial phases of plaque development on nonretentive tooth surfaces were studied bacteriologically in Macaca irus monkeys fed by stomach tube and provided with various oral supplements. Except for the oral implantation of Streptococcus mutans in some of the animals, the oral flora was not changed prior to the studi... | 825,462 | [
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... |
Neutralizing antibody to Pseudomonas aeruginosa exotoxin in human sera: evidence for in vivo toxin production during infection. | Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast, ... | 825,470 | [
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Changes in red blood cell volume on fixation in glutaraldehyde solutions. | Light scattering (nephelometry) was used to determine directly the change in volume of red blood cells immersed in a variety of buffer and fixative solutions. Cells immersed in saline or phosphate buffer solutions showed a change in volume that reflected the osmolarity of the solution, shrinkage taking place in hyperto... | 825,484 | [
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A methodological approach to rapid and sensitive monoamine histofluorescence using a modified glyoxylic acid technique: the SPG method. | A modified approach of the glyoxylic acid (GA) condensation reaction for the visualization of biogenic amines in tissue is described. Cryostat sections are used from brain or extracerebral tissue in dog, monkey, rat and mouse and exposed for 3 s to a room temperature solution containing sucrose-potassium phosphate-glyo... | 825,485 | [
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Immunochemistry of the subunits of transcarboxylase. | Antisera reactive with the subunits of transcarboxylase were produced by injecting rabbits with the 12 SH and 5 SE subunits prepared from trypsin-treated enzyme and with the 12 SH subunit prepared from native transcarboxylase by avidin-Sepharose chromatography. Biotinyl peptides (46 and 65 amino acid residues), release... | 825,513 | [
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0.3517036,
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Rubella hemagglutination-inhibition test: false-positive reactions in sera contaminated with bacteria. | We have shown that bacterial contamination of sera can have a marked influence on the results of the rubella hemagglutination-inhibition (HI) test. In addition to increasing the levels of nonspecific agglutinins, a number of common bacterial species tested had a significant effect on the HI titers. When sera free from ... | 825,529 | [
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... |
Gonococci causing disseminated gonococcal infection are resistant to the bactericidal action of normal human sera. | The susceptibility of strains of Neisseria gonorrhoeae to the bactericidal action of normal human sera was determined for isolates from patients with disseminated gonococcal infection and uncomplicated gonorrhea. Serum susceptibility was correlated with penicillin susceptibility and auxotype. 38 of 39 strains (97%) of ... | 825,532 | [
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The alteration of superoxide dismutase, catalase, glutathione peroxidase, and NAD(P)H cytochrome c reductase in guinea pig polymorphonuclear leukocytes and alveolar macrophages during hyperoxia. | Superoxide dismutase, catalase, glutathione peroxidase and NAD(P)H cytochrome c reductase were quantitated in polymorphonuclear leukocytes (PMN) and alveolar macrophages (AM) obtained from guinea pigs exposed up to 90 h to 85% oxygen. PMN and AM were sonicated and separated into a 16,000-g pellet, a 100,000-g pellet, a... | 825,533 | [
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... |
Doppler ultrasound diagnosis of testicular cord torsion. | The author confirmed clinical diagnosis of torsion of the testis with Doppler ultrasound flowmeters in 12 of 15 patients. Doppler examination in addition to clinical examination was more accurate than clinical examination alone. Problems were encountered when examining newborns, but progress in probe technology may yie... | 825,541 | [
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Retroperitoneal fibrosis: ultrasound findings and case report. | A case of idiopathic retroperitoneal fibrosis is reported with a description of the gray scale ultrasound findings. The mass was indistinguishable in appearance from many other retroperitoneal processes, such as lymphoma, fibrosarcoma, and liposarcoma. In this case the mass had a well-defined anterior border, and the p... | 825,544 | [
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... |
Study of rickettsioses in Slovakia. III. Experimental infection of Apodemus flavicollis Melch. by Rickettsiae of the spotted fever (SF) group isolated in Slovakia. | Experimental studies of infection of Apodemus flavicollis, and for comparison of rickettsiaemia in Clethrionomys glareolus and of susceptibility and antibody formation in white mice, with rickettsiae of the SF group isolated in Slovakia, gave the following results: The species A. flavicollis reacted by the formation of... | 825,571 | [
-0.09114436,
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0.1177653,
0.09899572,
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Resistance of Neisseria gonorrhoeae grown in vivo to ingestion and digestion by phagocytes of human blood. | Attempts to study quantitatively the phagocytosis of gonococci from urethral pus failed because of the small numbers of organisms and technical difficulties. However, gonococci from chambers implanted subcutaneously in guinea pigs, which were similar to gonococci from urethral pus in their resistance to killing by huma... | 825,610 | [
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Responses of fibers in medial longitudinal fasciculus (MLF) of alert monkeys during horizontal and vertical conjugate eye movements evoked by vestibular or visual stimuli. | Extracellular recordings were obtained from 37 histologically identified MLF fibers near the trochlear nucleus in alert monkeys trained to perform a visual tracking task and subjected to adequate horizontal and vertical vestibular stimulation. The behavioral paradigm permitted independent quantitative assessment of a f... | 825,618 | [
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... |
Effects of total parenteral nutrition and semi-starvation on the liver of beagle puppies. | The effects on hepatic growth of fat-free TPN and semistarvation have been studied in newborn beagle puppies. Our data indicate that liver growth during TPN is characterized by normal deposition of protein and minerals, with increased glycogen and decreased lipid content. While the lipid pattern of TPN livers is normal... | 825,628 | [
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[Late sequelae and complications in exclusive high voltage radiotherapy for carcinoma of the cervix uteri (author's transl)]. | This study deals with 524 cases of uterine cervix (except stade IV cases) completely treated at the Foundation Curie with esclusive radiotherapy from from 1962 to 1968. The irradiation techniques, as well as the doses given to the tumor and to the critical organs are stated. The various sequelae and complications are d... | 825,641 | [
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0.3201988,
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0... |
The relationship between total and ionized calcium in the blood sheep when calcium levels are altered. | In a series of eight experiments attempts were made to change the levels of calcium in the blood of sheep by intravenous infusions of calcium, EDTA and thyrocalcitonin or changing the acid-base balance by various means. When total calcium levels changed these changes were mirrored closely by changes in the physiologica... | 825,645 | [
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... |
Comparison of hemodynamic and regional blood flow changes at equivalent stages of endotoxin and hemorrhagic shock. | Hemodynamic, respiratory, and regional blood flow measurements were carried out in two groups of monkeys at three roughly equivalent stages of endotoxin and hemorrhagic shock. Comparisons revealed characteristic differences at the two early stages, particularly in systemic vascular resistance and the pattern of distrib... | 825,657 | [
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... |
[Bacteriological results from conjunctival swabs and anterior chamber aspiration of corneal donors (author's transl)]. | Bacteriological investigation of possible cornea donors' conjunctiva and aqueous humor were performed. The results show the importance of antibiotic prophylaxis before keratoplasty. | 825,678 | [
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[Complications of regional anesthesia (author's transl)]. | In spite of the great advances in anesthesia, regional anesthesia has not lost its importance. The development of new, longer-acting local anesthetics has extended its indication still more. The causes of accidents lie mostly in ignorance ofthe pharmacology of local anesthetics and their adjuvants, in faulty technical ... | 825,723 | [
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[Regional anesthesia in geriatric surgery. Possibilities and limitations: (author's transl)]. | Modern anesthetic techniques are superior to regional anesthesia for most operative procedures. Yet because of new advances in techniques and methods and sound pathophysiological knowledge, there are some operations for which regional anesthesia has distinct advantages over general anesthesia. This is the case, for exa... | 825,724 | [
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0.2390032,
0.1382227,
0.088837,
0.09940342,
0.05645638,
0.03177866... |
[Iodine-induced hypothyroidism (author's transl)]. | Excessive administration of iodine over a long period may cause hypothyroidism in suitably disposed individuals and provoke the formation of a goiter. The underlying reason for this is the pathological lack of adaptation of the thyroid gland to high doses of iodine with persisting inhibition of hormone production throu... | 825,727 | [
-0.08562973,
-0.2961746,
-0.413891,
-0.03159645,
0.5222576,
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0.376896,
0.2775337,
0.01967944,
0.3116844,
0.09049095,
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0.01004434,
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0.1075188,
0.1629404,
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... |
[Histological diagnosis and individual treatment of cancer in gynecology (author's transl)]. | Individualization of cancer therapy in gynecology is based on a perfectly precise histological diagnosis. This implies close cooperation between the clinician and the histopathologist. Making a reliable and therapeutically decisive histopathological diagnosis is possible by means of certain diagnostic interventions whi... | 825,738 | [
0.1814724,
0.2306932,
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0.09356462,
0.2518471,
0.5369475,
0.2572941,
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0.32... |
[The importance of liver scanning in pancreatic carcinoma (author's transl)]. | One of several liver scans were obtained in 29 patients with carcinoma of the pancreas. Scanning of the liver offers several advantages in cases of suspected carcinoma of the pancreas: (1) It may prove malignancy in jaundiced patients without a detectable primary tumor (frequency carcinoma of the pancreas). (2) It may ... | 825,739 | [
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0.2811273,
0.3034109,
0.3269949,
0.43335,
0.04590382,
0.06410102,
... |
[Malignant degenerative osteoneoplastic teratoma of the greater omentum (author's transl)]. | A case of teratoma of the greater omentum is reported, which occurred mainly in the form of a highly differentiated osteoma. In the marginal section the tumor showed embryonal structures with signs of degeneration which were found again in metastatic colonization in lymphnodes, pancreas, liver and peritoneum. The malig... | 825,742 | [
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0.4426144,
0.1432484,
0.1569974,
... |
[Treatment of chronic arterial circulatory disorders. Double blind trial with Trental 400 (author's transl)]. | For the objective determination of its efficacy, Trental 400 was examined against placebo in a double blind trial in 40 patients with chronic peripheral circulatory disorders and concomitant symptoms of cerebro-vascular insufficiency typical of age. Treatment lasted 7 to 8 weeks with a dosage of 1 tablet 3 times a day.... | 825,745 | [
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0.0868587,
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0.2414917,
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0.5412945,
0.06113312,
0.2522303,
0.0118710... |
[Effective therapy of chronic arterial circulatory disorders with Nico-Padutin forte (author's transl)]. | Over a period of 6 weeks, 90 patients of both sexes (principally male) aged from 38 to 81 years were treated with Nico-Padutin forte (BAY b 7979; 40 units kallikrein + 300 mg inositol nicotinate) for chronic arterial disorders of the lower extremities. Positive therapeutic results were obtained in 82 cases (91.2%) with... | 825,753 | [
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0.4233728,
0.2407836,
0.01151691,
0.1880578,
... |
Paper point transfer of minimal numbers of microorganisms from a prepared canal in vitro. | A strain of Str. faecalis resistant to 2 mg./c.c. streptomycin was developed, and serial dilutions of known quantities of the organism were introduced into prepared root canals of extracted teeth. The canals were cultured with sterile dry paper points, incubated in tubes of thioglycollate media containing 2 mg./c.c. st... | 825,804 | [
-0.02980534,
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0.001528941,
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0.1532425,
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0.4168803,
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0.2659705,
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0.041937,
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0.33779,
0.005955521,
0.3437968,
0.18992... |
Conditioned behavioral and physiological changes associated with injections of a narcotic antagonist in morphine-dependent monkeys. | Environmental stimuli which are repeatedly associated with the nalorphine-induced withdrawal syndrome in morphine-dependent monkeys acquire the ability to produce a variety of conditioned behavioral and physiological responses. Morphine-dependent rhesus monkeys were studied under a fixed-ratio schedule where every tent... | 825,815 | [
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0.0996777,
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0.1088247,
0.110594,
0.2138323,
0.3187977,
-0.07657643... |
Sequence determination of the 3' terminal T1 oligonucleotide of 18S ribosomal RNA. | We have reexamined the primary structure of the 3' terminal oligonucleotide of 18S RNA from chicken fibroblasts and have shown, contrary to previously published results that this extremity G-A-U-C-A-U-U-AOH is identical to that of the rabbit, drosophila and bombyx. Furthermore the electrophoretic mobility and compositi... | 825,835 | [
0.2326055,
0.06734975,
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0.4688431,
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0.1255532,
0.3602403,
0.2703861,
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... |
Production and diagnostic application of anti-human T-cell antisera. | This paper is intended to demonstrate the extension of experimental procedures used for the production of anti-chicken T-cell sera to the manufacturing of anti-human T-cell sera. Specific anti-chicken bursa (ABS) and anti-chicken thymus cell sera (ATS) were prepared in turkeys. The in vitro specificity of these sera wa... | 825,844 | [
0.09243746,
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0.07264898,
0.3102601,
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0.2350214,
0.2665891,
0.1768246,
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0... |
Short-term memory in the rhesus monkey: disruption from the anti-cholinergic scopolamine. | Two separate experiments were conducted to evaluate the effects of the anti-cholinergic scopolamine on primate visual discrimination and short-term memory (STM). In the first experiment it was shown that relatively mild doses of scopolamine severly impaired visual discrimination performance, even though the test proced... | 825,880 | [
-0.007096013,
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0.06337799,
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0.1813772,
0.014021,
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TRH by slow, continuous infusion: an antidepressant? | A slow, continuous infusion of 1000 mug TRH (thyrotropin releasing hormone) over a period of 4 h had a very faint and diffuse short-lasting beneficial effect on a group of 10 depressive patients. This was assessed in a double blind cross-over trial with placebo. The effect was of no therapeutic value. No difference was... | 825,895 | [
0.1570558,
0.1900164,
-0.02231536,
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0.01390349,
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0.1858146,
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0.007779823,
0.05578104,
0.2475242,
-0.0128973... |
Effects of cholinergic agonists and antagonists on morphine-withdrawal syndrome. | The effects of pilocarpine, atropine and dexetimide were studied on the occurrence and intensity of morphine-withdrawal signs observed after cessation of chronic morphine injections. Pilocarpine was effective in reducing both 'wet-dog' like body shakes and aggression but it increased diarrhea and weight loss. Pretreatm... | 825,907 | [
0.09337755,
0.1489044,
0.02822625,
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0.2127298,
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0.2802753,
0.5040513,
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... |
Composition of the subscribers in a rural prepair group practice plan. | To determine the degree to which enrollees of the Greater Marshfield Community Health Plan were representative of the community the plan was designed to serve, a telephone survey of 1,838 households in the 30-township area was undertaken. The response rate was 93%, and data were obtained from 1,718 households containin... | 825,914 | [
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0.131793,
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0.04951617,
0.1066453,
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0.2127407,
0.1586001,
0.01589614,
... |
Design and test of a system for tracking referrals. | Many health and welfare programs are based on a model in which services needed by consumers are identified by one agency with referral to others for provision of services. The referring agency often does not know whether the services recommended are received, yet it is assumed that receipt of those services by their cl... | 825,917 | [
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0.3215204,
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0.08742088,
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0.1326059,
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0.08950775,
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0.2162958,
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0.07638495,
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0.2230675,
0.06394773,
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0.02369269,
-0.03042... |
[The fine structure of liver sinusoids after perfusion fixation with various pressures. A transmission and scanning electron microscopic study (author's transl)]. | The fixation of rat liver by perfusion with glutaraldehyde with different pressures has been investigated. For this study adult male albino rats were used. Rat livers were fixed by perfusion through the abdominal aorta according to the method of FORSSMANN et al. (1967). Perfusion pressures varied from 30 to 210 mmHg. A... | 825,939 | [
-0.04103981,
0.1020151,
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0.201288,
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0.1090432,
0.1049934,
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0.215426,
0.2663816,
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0.1889565,
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0.02552718,
0.016... |
Structural studies of induced antibodies with defined idiotypic specificities. IV. The heavy chains of anti-streptococcal group A carbohydrate antibodies from Sprague-Dawley rats carrying a cross-reacting idiotype. | The heavy (H) chains of three anti-streptococcal group A carbohydrate antibodies (anti-SACHO) of restricted heterogeneity, elicited in inbred Sprague-Dawley rats, were subjected to 40 cycles of automated Edman degradation. All three antibody H-chain preparations had an identical amino acid sequence and were classified ... | 825,960 | [
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0.1005811,
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0.2771462,
0.17678,
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0.134513,
0.1198748,
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0.1602299,
-0.1951696,
0.2444238,
0.09440028,
-0.3675678,
-0.07... |
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