title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The development of a radioimmunoassay for arginine vasopressin. | The development of a sensitive and specific radioimmunoassay for vasopressin is described. Antibodies were successfully produced following the coupling of synthetic arginine vasopressin with bovine serum albumin carried out with carbodiimide. In order to standardize the assay, the labelled hormone has to be separated t... | 822,668 | [
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The distribution of B and T lymphocytes in the peripheral blood of patients with Hodgkin's disease. | The distribution of thymus-dependent (T cells) and bone marrow-derived lymphocytes (B cells) was studied in 74 patients with Hodgkin's disease and 33 normal controls. A T cell deficit was found in untreated patients as well as in long-term survivors in remission. Therapy slightly enhanced the T cell depletion in Hodgki... | 822,670 | [
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Favism in a Portuguese family due to a deficient glucose-phosphate dehydrogenase variant (Canton) or (cpanton-like) type. | In a Portuguese boy with favism G-6PD deficiency was found. Deficiency was due to a G-6PD variant close or identical to Canton-type G-6PD. The muted protein had a lowered catalytic activity and furthermore, was unstable. The post-translational modifications undergone by this deficient G-6PD variant are described. | 822,676 | [
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Histochemical and biochemical properties of the labial and palatine glands and their secretions in the Macaca irus and Cercopithecus aethiops monkeys. | The increasing use of non-human primates in experimental studies in dentistry demands detailed knowledge of their basic oral biology. The labial and palatine glands and their secretory products were compared in two commonly used monkey species. The mucous cells of both gland types appeared to elaborate sulphated muco-s... | 822,685 | [
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Peritoneal dialysis in hypernatraemic, ketoacidotic diabetic coma. | Hypertonic dehydration in a 13-year-old boy with ketoacidotic diabetic coma has been treated successfully with peritoneal dialysis and isotonic fluids. Modes of treatment with either hypotonic or isotonic fluids are discussed, as is the feasibility of peritoneal dialysis. We recommend isotonic solutions composed of equ... | 822,694 | [
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Effects of isosorbide dinitrate and nitroglycerin on central circulatory dynamics in coronary artery disease. | This study compares the effects and duration of the effects of 5 mg. of sublingual (SL) isosorbide dinitrate (ISD), 20 mg. of oral ISD, and 0.4 mg. of SL nitroglycerin (TNG) on central circulatory dynamics. Twenty-seven patients with coronary artery disease were evaluated with radioisotope techniques and determinations... | 822,703 | [
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Time and money for vocational rehabilitation of clients with mild, moderate, and severe mental retardation. | Mildly, moderately, and severely mentally retarded vocational rehabilitation clients comprised a random national sample of 600 clients. One-half of the sample had been closed (services completed) "rehabilitated", and half had been closed "nonrehabilitated." Variables selected for analyses were time in referral, trainin... | 822,715 | [
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Umbilical vein occlusion and transient acceleration of the fetal heart rate. Experimental observations in subhuman primates. | Transient acceleration of the fetal heart rate is commonly seen in the cardiotachometer tracing of the human fetus during labor. A likely cause appeared to be partial occlusion of the umbilical cord. On the basis of this hypothesis, fetal cardiovascular responses to partial occlusion of the umbilical cord or isolated i... | 822,718 | [
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[Insulin]. | After a short survey of the different methods for the radioimmunological dosage of insulin, the significance of insulinaemia in fasting conditions and of the insulinaemic curves after stimulation is taken into consideration as regards some physiological aspects. Dosage of insulin in the study of various pathological c... | 822,767 | [
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[An acellular vaccine from "Pseudomonas aeruginosa." I. Preparation and activity (author's transl)]. | From a strain (72 V) of Pseudomonas aeruginosa, we have prepared an acellular vaccine P2, which showed a good efficiency against homologous experimental infection in mice. The extraction procedure is as follows: washed bacterial cells are suspended in 0,15 M NaCl and heated at 60 degrees centigrade for 1 hr; after cent... | 822,769 | [
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Norwegian scabies: occurrence in a patient undergoing immunosuppression. | Norwegian scabies is rare yet distinctive. The majority of reported cases have been in patients with relatively small group of diseases, including Down syndrome and lepromatous leprosy. A case occurred in a patient on long-term immunosuppressive therapy following a kidney transplant. Altered host factors appear to be t... | 822,784 | [
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The absorption, distribution and metabolic fate of danazol in rats, monkeys and human volunteers. | The metabolism of danazol has been investigated in the rat, the monkey and in human volunteers using 14C-isoxazolo-, 14C-ethynyl, 6,7-tritiated and unlabelled compound. The drug was well absorbed, and rapidly metabolized; approximately 60 endproducts were seen in monkey urine. Four compounds have been unequivocally ide... | 822,792 | [
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Uptake and incorporation of pyrimidines in Euglena gracilis. | In photoorganotrophically grown cells of Euglena gracilis the uptake and incorporation degree of 12 different pyrimidines were tested. The rate of uptake of pyrimidines has distinct maxima in the late log phase and in the stationary phase of cell multiplication. The kinetics of uptake are linear in the first 2 h, do no... | 822,794 | [
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Some physiological functions of the L-leucine dehydrogenase in Bacillus subtilis. | Mutants of Bacillus subtilis constitutive for L-leucine dehydrogenase synthesis were selected. Using these mutants we could determine two functional roles for the L-leucine dehydrogenase. This enzyme liberates ammonium ions from branched chain amino acids when supplied as the sole nitrogen source. Another function is t... | 822,797 | [
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[Sphingolipid storage disease as an example of a molecular neuropathology (author's transl)]. | A short survey on the sphingolipid storage diseases is presented. The chemical nature of the accumulated substances is related to the genetically induced enzymic blocks on their biodegradation. Two disorders are stressed with alter the nervous system: metachromatic leukodystrophy and familiar infantile amaurotic idiocy... | 822,805 | [
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Developmental origin of even spacing between the microchaetes of Drosophila melanogaster. | In D. melanogaster, evenness of spacing is a prominent feature of the patterns of microchaetes. As a general explanation of this characteristic, Wigglesworth has suggested a scheme whereby some epidermal cells become singled out (determined) at random to differentiate bristles, and the same potential in neighbouring ce... | 822,814 | [
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Partial amino acid sequences of kappa-chains of rat immunoglobulins: genetic and evolutionary implications. | Partial amino acid sequences have been determined for several kappa-type light chains prepared from sera or urine of inbred LOU/C/Wsl rats bearing plasma cell tumors. Comparison of these sequences with those of human, rabbit, and mouse kappa-chains available in the literature indicates that the constant region of rat k... | 822,831 | [
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Evidence for the adaptive significance of enzyme activity levels: interspecific variation in alpha-GPDH and ADH in Drosophila. | The activity levels of alcohol dehydrogenase and alpha-glycerophosphate dehydrogenase were compared among nine species of Drosophila representing three phylogenetic groups. For any given life stage , interspecific variability in activity level was much greater for ADH than for d-GPDH. Patterns of ontogenetic expression... | 822,837 | [
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Non-human primate platelets and arterial tissue cannot convert preformed [14C]lanosterol into[14C]cholesterol in vivo. | In contrast with the prevailing view, we report the inability of non-human primate platelets or arterial tissue to complete the biosynthesis of [14C]cholesterol from [14C]mevalonic acid in vitro or in vivo, or from performed [14C]lanosterol in vivo. The latter observation suggests that these tissues lack one or more co... | 822,845 | [
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Triple-drug therapy of chronic glomerulopathies. | Prolonged combined treatment with prednisone and immunosuppressive drugs can, if started early enough, significantly reduce the degree of proteinuria and preserve renal function. This is not necessarly associted with simultaneous histological improvement confirmed by renal biopsy. The proposed method of treatment deser... | 822,859 | [
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Chromatographic separation on phosphocellulose of activated and nonactivated forms of steroid-receptor complex. Purification of the activated complex. | Steroid-receptor complexes formed at low temperature and ionic strength are unable to bind to target cell nuclei. After a temporary exposure to high ionic strength and/or temperature they become activated (i.e., able to bind to nuclei). However, there exists an equilibrium between activated and nonactivated complexes; ... | 822,870 | [
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The influence of salt on the aggregation state of spectrin from bovine erythrocyte membranes. | Sedimentation velocity and gel filtration experiments have been performed with bovine spectrin over a wide range of neutral salt concentrations. Increasing salt concentrations tend to increase both the sedimentation coefficient of spectrin and the elution volume of the protein from 4% agarose columns. No conformation c... | 822,876 | [
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Penicillin sensitivity of gonococci. An evaluation of monitoring as an index of epidemiological control. | The penicillin sensitivities of 1,167 gonococci isolated during a 30-month period from male patients, and 794 gonococci isolated from female patients were analysed retrospectively. More strains from males were relatively resistant than those from females, and a higher proportion of relatively resistant organisms was is... | 822,915 | [
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Effects of castration and androgen-substitution on the morphology of the epididymal epithelium of the Japanese monkey, Macacus fuscatus, as revealed by scanning electron microscopy. | The caput epididymidis from castrated and androgen-supplemented, castrated Japanese monkeys was observed with the scanning electron microscope. The experimental findings were compared with the normal structures in control animals. The epididymal lumen of control animals was lined by a tall, pseudostratified columnar ep... | 822,942 | [
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[Effects of artificial light, distributed through long photophases, on the annual growth cycle of the crayfish Orconectes limosus (Raffinesque)]. | A photophase of 18 hrs interrupts the annual anecdysis of Orconectes limosus, which does not constitute an irrefutable evidence of a photoperiodic control in the cessation of anecdysis, since molts are also induced during the annual rest by an abnormally high temperature after a stay at low temperature. On the contrary... | 822,950 | [
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Polyacrylamide-gel disc electrophoresis of unconcentrated urine samples with special reference to Bence Jones proteins. | The polyacrylamide-gel disc electrophoresis has been applied to the fractionation of 27 samples of unconcentrated urine obtained from the patients with monoclonal gammopathy. It was shown that 44% of the whole Bence Jones protein bands examined were detected in the area between 0.70 and 0.90 expressed in terms of relat... | 822,967 | [
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Rapid prenatal diagnosis of GM1-gangliosidosis using microchemical methods. | Prenatal diagnoses were established in 3 pregnancies at risk for GM1-gangliosidosis at 9, 10, and 12 days after amniocentesis. Beta-galactosidase activities in cultured amniotic fluid cells were determined by microchemical assays in cell homogenates and in isolated groups of 10--30 freeze-dried cells. The latter method... | 823,094 | [
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Partial characterization of a factor extracted from sensitized lymphocytes that inhibits the growth of Mycobacterium tuberculosis within macrophages in vitro. | Spleen lymphocytes of BCG-immunized mice contain a soluble factor that inhibits in vitro the growth of the H37Rv strain of Mycobacterium tuberculosis within normal peritoneal macrophages. The water-soluble extracts of sensitized lymphocytes, disrupted by freezing and thawing, although less active than the corresponding... | 823,109 | [
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Platelet glycocalicin. I. Orientation of glycoproteins of the human platelet surface. | The orientation of proteins and glycoproteins of the platelet surface has been studied using various surface probes and labeling reagents. A fourth major glycoprotein has now been detected in platelet plasma membranes by sodium dodecyl sulfate-gel electrophoresis in addition to the previously recognized glycoproteins I... | 823,154 | [
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Gas chromatographic determination of polychlorinated biphenyls and some chlorinated pesticides in sewage sludge using a glass capillary column. | Gas chromatographic methods for the determination of polychlorinated biphenyls and DDT (with some of its metabolites) in sewage sludge samples and similar materials are described. The sample is extracted with a mixture of hexane, acetone and water. After separation, the hexane phase is reduced in volume and divided int... | 823,167 | [
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Comparison of immunodiffusion and complement fixation tests in the diagnosis of histoplasmosis. | The immunodiffusion and complement fixation tests for histoplasmosis were compared on 2,090 initial sera from 70 proven cases of histoplasmosis, 177 routine chest hospital patients, and 1,843 coal miners from outside the major endemic area for histoplasmosis. The complement fixation test using histoplasmin as antigen d... | 823,169 | [
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Renal prostaglandin synthesis in the spontaneously hypertensive rat. | The precise role of the kidney in spontaneous experimental hypertension is unknown. We have analyzed the rates of renal prostaglandin synthesis by utilizing a spontaneously hypertensive rat model. The synthetic rate of prostaglandin E2, prostaglandin F2alpha, and prostaglandin A2-like products was measured in vitro wit... | 823,178 | [
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Areal and laminar distribution of some pulvinar cortical efferents in rhesus monkey. | The areal and laminar distribution of the cortical efferents of the medial, lateral and inferior pulvinar nuclei (PM, PL and PI respectively) were determined in rhesus monkey using autoradiography and Horseradish Peroxidase (HRP). The autoradiographic data indicated that: areas 8a, 45 and 46 on the convexity and 11 and... | 823,181 | [
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An ergot alkaloid preparation (Hydergine) in the treatment of dementia: critical review of the clinical literature. | A critical review is presented of 12 clinical trials with Hydergine (a hydrogenated ergot alkaloid preparation) in the treatment of dementia. Qualitative and quantitative comparisons of improvement in symptoms showed that Hydergine consistently produced statistically significant (p less than or equal to 0.05) improveme... | 823,192 | [
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The use of non-human primates for production of antisera to human tumor-associated antigens. | High-titered antisera against human melanoma- and leukemia-associated antigens have been produced in non-human primates. The data from this and from other studies suggest that this model may prove a valuable source of highly specific antisera against a variety of human tumor-associated antigens or alloantigens. Our met... | 823,260 | [
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Clinical correlation of strain differentiation of Neisseria gonorrhoeae. | An in vitro bactericidal assay that utilized a set of 20 typing antisera to Neisseria meningitidis was developed to distinguish differences in strains of Neisseria gonorrhoeae based on patterns of killing. When test conditions were rigidly standardized, the method was sensitive and reproducible. Strains of gonococci fr... | 823,271 | [
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Laboratory findings of tobramycin and their relation to clinical response. | The susceptibilities of various clinical isolates to tobramycin were studied, and the applicability of these data to clinical situations was evaluated. The bactericidal nature of tobramycin was confirmed by killing curves, and the minimal inhibitory concentrations for 500 common pathogens were used to define its spectr... | 823,277 | [
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Comparative in vitro activity of tobramycin, gentamicin, kanamycin, colistin, carbenicillin, and ticarcillin and clinical isolates of Pseudomonas aeruginosa: epidemiological and therapeutic implications. | The susceptibility of clinical isolates of Pseudomonas aeruginosa to six antibiotics was related to the epidemiologic knowledge yielded by serotyping. The agar dilution method for determination of minimal inhibitory concentrations (MICs) and the Habs serotyping system were used. Effectiveness of each agent ranked highe... | 823,279 | [
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The effect of diet on hepatic bile formation and bile acid metabolism in squirrel monkeys with and without cholesterol gallstones. | In order to explain why squirrel monkeys on some experimental diets develop cholesterol gallstones, we made a number of measurements on bile acid kinetics and on bile secretion and composition. The pool size of cholic acid was much greater in monkeys on a commercial diet than in any group on a semipurified diet. It was... | 823,283 | [
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Mammalian carbonic anhydrase isozymes: evidence for a third locus. | Starch gel electrophoretic patterns of carbonic anhydrase (CA) isozymes were examined from tissue extracts of sheep, mice, rabbits, and chickens. In addition to the widely distributed and extensively studied B and C isozymes, an additional isozyme (called CA-A) was observed, which was predominantly localized in muscle ... | 823,290 | [
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Primate model for testing periodontal treatment procedures: II. Production of contralaterally similar lesions. | Experimental periodontal pockets were produced bilaterally in four Rhesus monkeys. The pockets were analyzed histometrically and the resultant data were subjected to statistical analysis. There were but few significant differences between pockets on contralateral tooth surfaces, and in each case, the magnitudes of the ... | 823,319 | [
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Inhibition of P-enolpyruvate carboxykinase and of glyconeogenesis in Tetrahymena by 3-mercaptopicolinic acid. | Tetrahymena grown overnight in deep cultures were incubated for 1 hr with [1-14C]labeled substrates in the presence or absence of 3-mercaptopicolinic acid (3MPA). 3-MPA inhibited appearance of label in glycogen from bicarbonate, acetate, pentanoate, octanoate, and succinate, but not from glycerol or glucose. In vitro a... | 823,332 | [
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Fractionation of RNA from tetahymena by affinity chromatography on poly-U-Sepharose. | Exponential growing Tetrahymena pyriformis organisms were labelled with (3H) uridine or (3H) adenosine. The labelled RNA was extracted and isolated by affinity chromatography on poly-uridylic-acid sepharose and further analysed by means of sucrose gradient centrifugation and RNase digestion. Experimental evidence prove... | 823,341 | [
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[New aspects in the treatment of the hypernephroid carcinoma of the kidneys (author's transl)]. | The nowadays best treatment of the hypernephroid carcinoma of the kidneys is the radical tumornephrectomy with following supervoltage-radiation. Recently before any surgical treatment a short radiation with a dose of 1 500 up to 2 000 R is recommended. Hereby a preoperative devitalization of tumor-cells should be achie... | 823,343 | [
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[Treatment of inflammatory diseases of the mouth and throat with Larypront in ENT practice (author's transl)]. | Treatment of inflammations of the oral and pharyngeal cavities (glossitis, pharyngitis, pharyngolaryngitis, tonsillitis) in 60 patients with Larypront Throat Tablets alone, without administration of systemic antibiotics, gave very good results in 49 cases (81.6%) with complete regression of the complaints in 3-4 days. ... | 823,423 | [
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Morbidity of therapeutic abortion in Auckland. | Twenty-six women were admitted to National Women's Hospital with complications following therapeutic abortion at the Auckland Medical Aid Centre, during its first year of operation. This represents 1.4 percent of the total number of cases at the Centre that year. The principal early complicatons were pelvic sepsis, sus... | 823,474 | [
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Hypophosphataemia and paraesthesias during parenteral nutrition. | Parenteral nutrition was instituted in a malnourished woman with a low serum phosphorus. In spite of a moderate phosphorus intake, the serum phosphorus descended to very low levels before returning to a normal range. Over a three week period she was troubled by paraesthesias, numbness, and a generalised weakness. The c... | 823,475 | [
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Marked hydrophobicity of the NH2-terminal extra piece of immunoglobulin light-chain precursors: possible physiological functions of the extra piece. | mRNAs coding for mouse immunoglobulin light chains direct the cell-free synthesis of precursors in which extra peptide segments precede the NH2-termini of the mature proteins. The abundance (18-30%) of leucine residues in the extra piece indicates that it is quite hydrophobic [Schechter and Burstein (1976) Biochem. Bio... | 823,549 | [
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Effects of apomorphine and haloperidol on the acoustic startle response in rats. | A series of 3 experiments tested the effects of 0.01, 0.04, 0.19, 0.75, 3.00, and 6.00 mg/kg apomorphine and 0.13, 0.25, and 0.50 haloperidol on the acoustic startle response in rats. Apomorphine markedly facilitated startle amplitude for about 40 min after injection and then depressed startle over the next 40 min. Bot... | 823,557 | [
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Drug-induced rotation in rats without lesions: behavioral and neurochemical indices of a normal asymmetry in nigro-striatal function. | Normal unoperated rats were tested for rotation (i.e., circling behavior) in a spherical "rotometer" and dose-response relationships were generated using d-amphetamine, apomorphine, L-Dopa, haloperidol, and scopolamine. The rotation induced by amphetamine was significantly antagonized by alpha-methyl-p-tyrosine and hal... | 823,560 | [
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Effects of lithium on open field behavior in "stressed" and "unstressed" rats. | Rats were tested for 3 min per day, for 4 successive days, in an open field apparatus, 20 min after injection of either lithium chloride (2 mEq/kg) or physiological saline. In the first experiment, the open field was illuminated with moderate white light for some rats (stress condition) and dim red light for others (no... | 823,583 | [
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Effect of estrogen on activity of prostaglandin synthetase in rabbit oviduct. | The activity of the prostaglandin synthetase system in the ampulla and isthmus of the rabbit oviduct has been studied in vitro. Thirty hours after an injection of estrogen the isthmus produced significantly more total prostaglandins following 9 minutes of incubation than the ampulla. These values were not, however, sig... | 823,606 | [
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... |
Congenital tuberculosis. | Congenital tuberculosis is a rare and often fatal disease. This report concerned a premature infant in whom the disease was found after postpartum diagnosis in the mother. Use of endotracheal tube aspirates to diagnose tuberculosis in the infant is a unique feature of this case. | 823,645 | [
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[Transplacental blastomogenesis in mice under conditions of the detoxifying function of the mother's body]. | The experiments on mice of line SHR have shown that in animals, delivered by Cesarean section I hour following intrauterine injection of 40 mg/Kg of DMBA in mothers (a period of maximum concentration of the carcinogen in the tissues of foetuses) and sacrificed one year later, carcinogenesis proceeded much more intensiv... | 823,707 | [
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Cold lymphocytotoxins. Chromatographical study. | A chromatographical study was made of eight antisera containing either anti-HL-A antibodies, cold lymphocytotoxins, or a mixture of both types of antibodies. The results vary according to the sera obtained. Usually cold lymphocytotoxins are sited in the IgM peak and anti-HL-A antibodies in the IgG peak, but there are s... | 823,710 | [
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0.09036898,
0.310338,
0.3914367,
0.01732055,
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[Behavior of leucine aminopeptidase from bovine eye lens in guanidine hydrochloride. Dissociation and reassociation]. | The dissociation and reassociation behavior of the hexameric leucine aminopeptidase (LAP) in solutions of 0.5 to 6 M guanidine-HC1 (Gu-HC1) was investigated by means of thin layer chromatography on Sephadex G-200 superfine. Up to 0.5 M Gu - hc1 the hexameric LAP-structure remains intact. In 0.75 to 2 M Gu - HC1 the enz... | 823,751 | [
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0.01453... |
The automation of microspectrophotometry of tissue sections. | A system for quantitative microspectrophotometry with automatic data acquisition is described. It is relatively simple and less expensive than presently-available equipment. Fitted with the appropriate software, the system permits various types of probe selection, with both selection and measurement made under individu... | 823,768 | [
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[The histochemical demonstration of a zinc activated, tartrate resistant acid phosphatase (author's transl)]. | An acid phosphatase which is highly activated by zinc acetate is demonstrated histochemically in the medulla of adrenal gland of the rat. It is shown that the acid phosphatases demonstrable histochemically in the medulla of adrenal gland are strongly inhibited by sodium tartrate while acid phosphatase demonstrable hist... | 823,771 | [
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[Passive electrical investigations on the normal and atherosclerotic human aorta in the alpha-dispersion area (author's transl)]. | The passive electrical behaviour of the normal and the atherosclerotic human aorta was investigated at frequencies between 20 Hz and 50 kHz. A distinct alpha-dispersion area with characteristic frequencies of 280 and 104 Hz respectively was found in the normal vessel wall as well as in the atherosclerotic plaques. The ... | 823,772 | [
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Studies on the physiology of pollen and pollen tube growth. 1. pinus roxburghii. | Pollen grains and pollen tubes of Pinus roxburghii were subjected to histochemical technique with a view to determining the distributional pattern of reserve substances (ascorbic acid, proteins starch, polysaccharides, nucleic acids) and some enzymes (acid phosphatase, glucose-6-phosphatase, peroxidase, esterase, cytoc... | 823,783 | [
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The diameter and number of dentinal tubules in rat, cat, dog and monkey. A comparative scanning electron microscopic study. | The aim of the study was to investigate in commonly used experimental animals the pulpal wall and the dentin with special reference to the number and diameter of the dentinal tubules. The coronal dentin of a total of 26 permanent, intact teeth from rat, cat, dog and monkey was fractured experimentally. The calculations... | 823,791 | [
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Tuberculin shock in red mice and CF1 mice immunized with strains of BCG or Mycobacterium tuberculosis. | Groups of red mice and CF1 mice immunized intravenously with varying doses of a weak and a strong strain of BCG and a strain of M. tuberculosis were challenged 3-4 weeks later with 2 or 0.5 mg of purified tuberculin injected intravenously. The shock sensitivity of the animals in the individual groups was evaluated on t... | 823,795 | [
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Pharmacotherapy of asthma. | The pharmacological management of asthma is reviewed. Drugs discussed include: (1) sympathomimetic amines, (2) theophylline, (3) cromolyn sodium and (4) corticosteroids. Aspects of treatment discussed include: initial evaluation, therapy for acute symptoms, and chronic asthma. | 823,821 | [
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[Host range of drosophila melanogaster C virus among diptera and lepidoptera (author's transl)]. | The host range of the C picornavirus of Drosophila melanogaster was studied, using numerous strains of Drosophila together with four other genera of diptera and two species of lepidoptera. C virus was injected into the different hosts and serially passaged in them. The extracts from each passage were biologically assay... | 823,856 | [
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Combinations of antimicrobial agents. III. The in vitro sensitivity of 12 strains of Pseudomonas aeruginosa and 12 strains of proteus species ot sulphamethoxazole + trimethoprim (co-trimoxazole), polymyxins and combinations of co-trimoxazole and polymyxins. | The sensitivity of 12 strains of Pseudomonas aeruginosa and of 12 strains of Proteus species to co-trimoxazole, polymyxins and combinations of co-trimoxazole and polymyxins was determined by disc and tray methods. It was found that all strains were sensitive to the combinations of co-trimoxazole and polymyxins. The dis... | 823,875 | [
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... |
Permanent extracorporeal esophagogastric tube for esophageal replacement. | Six patients are presented in whom an extracorporeal esophagogastric tube bypass was employed in lieu of standard methods of esophageal reconstruction. These tubes, obtained from Japan, have functioned well in 4 of the 6 patients. This approach offers an alternative to gastrostomy feedings alone in a patient with advan... | 823,881 | [
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Infective endocarditis following human-to-human enterococcal transmission: a complication of intravenous narcotic abuse. | Two heroin addicts, husband and wife, who shared injection paraphernalia extensively, developed enterococcal endocarditis within six weeks of one another. The etiologic organisms were of the same subspecies and had identical antibiotic susceptibilities and biochemical profiles. The clinical, epidemiologic, and bacterio... | 823,882 | [
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[Hemagglutinating activity of Candida albicans culture extracts]. | 3M KC1 extracts of Candida albicans cultures display a haemoagglutinating activity on human and sheep red blood cells. The haemoagglutinins, may be lectins in nature, behave like antigens being fully inhibited by anti-Candida immune serum. The latter lyses human red blood cells sensitized with 3M KC1 Candida albicans e... | 823,878 | [
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[Ischemic lesions of the left branch of the bundle of His. Their relation of left hemiblock]. | The term "hemiblock of the left branch of the bundle of His" seems to a histologist to be too precise to be accepted without reservation. Ten cases with septal infarction, with or without left intraventricular conduction problems, were studied by serial sectioning of the heart; these are used as a basis for a discussio... | 823,886 | [
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[Long term results of surgical treatment of obstructive myocardiopathy by intervention on the interventricular septum]. | An analysis of the results of septal myotomy or myectomy in 26 adults with obstructive cardiomyopathy (OCM) with a mean follow-up period of more than 5 years lead to the conclusion that this treatment brings about, at the price of a mortality rate of about 10%, a sustained improvement in function, a reliable correction... | 823,918 | [
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Treatment of Vaccinial keratitis with trifluorothymidine. | The efficacy of trifluorothymidine was compared with idoxuridine on a blind basis by noting the effect of topical administration of the drugs on the severity of vaccinial keratitis induced in rabbits. Trifluorothymidine was found to be substantially more effective, and was well tolerated. In addition, positive viral cu... | 823,931 | [
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The use of supplementary tests in the serological diagnosis of bovine brucellosis. | Comparative tests were carried out on serum samples using the Rose Bengal test (RBT), the complement fixation test (CFT), the antibovine globulin test (ABGT) by tube, plate and rapid variants, the mercaptoethanol test (MET) and the dithiothreitol test (DTT). Forty cows, from which Br. abortus had been recovered, gave s... | 823,932 | [
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Ages and frequencies for cervical cancer screening. | A simple method of calculating the best ages for carrying out cervical cytology screening procedures is proposed. The argument is graphical, the outcomes are readily understood by visual and intuitive methods, but a computer program for assisting the calculations is constructed. Use of the method indicates that relativ... | 823,954 | [
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Stabilization by glutaraldehyde of high-rate electron transport in isolated chloroplasts. | Treatment of isolated chloroplasts with glutaraldehyde affects their ability to photoreduce artificial electron acceptors. The remaining rate of O2 evolution approaches zero with methyl viologen, is low with ferricyanide, but nearly normal with lipophilic Photosystem II acceptors, like oxidized p-phenylenediamine and o... | 823,976 | [
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Convulsions or flaccid paralysis induced by ruthenium red depending on route of administration. | Ruthenium red was administered to mice and cats intracranially or intraperitoneally. In mice, intracisternal administration produced status epilepticus and tonic convulsions. In contrast, intraperitoneal administration induced total flaccid paralysis lasting several hours. These effects of Ruthenium red were partially ... | 824,018 | [
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... |
Etidronate disodium in postmenopausal osteoporosis. | Calcium-balance, calcium-kinetic, and physiologic observations were made in 10 osteoporotic patients treated for 6 to 12 mo with disodium etidronate (EHDP) in oral doses of 20 mg/kg/day. Absorption of EHDP averaged 10%, and effective retained dose was approximately 1.6 mg/kg/day. Patient acceptance was excellent, and t... | 824,086 | [
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[Haemolytic disease of the new-born by blood-factor incompatibility other than Rh(d) and ABO (author's transl)]. | Rare forms of incompatibility were observed over a period of 20 years in 41 (2%) of 2088 new-borns with haemolytic disease. Antibodies involved were anti-c (n = 27), anti-E (n = 6) and anti-K (n = 4), as well as one case each of anti-E + Fya, -C, -Fya and -Jka. Amniotic fluid was examined during pregnancy in nine cases... | 824,115 | [
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... |
Binding of (T,G)-A--L by normal sera. | The synthetic polypeptide poly-L-(Tyr, Glu)-poly-DL-Ala--poly-L-Lys [(T,G)-A--L] was found to be bound not only by mouse immune serum, but also by nonimmune sera from several species. A combination of immunoelectrophoresis and autoradiography showed that albumin, beta-globulins and immunoglobulins in these sera may bin... | 824,136 | [
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Antibody-dependent human lymphocytotoxicity: a micro assay system. | A micro assay system is described for measuring antibody-dependent lymphocytotoxicity with human effector cells. The target cells were mouse mastocytoma cells sensitized with rabbit antibody. The tests were performed in microtiter plates, each well containing 5 x 10(3) 51Cr-labeled target cells, together with varying n... | 824,141 | [
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A study of immunoglobulin classes present on the membrane and in the cytoplasm of human tonsil plasma cells. | The problem of whether immunoglobulin (Ig)-containing plasma cells expressed membrane Ig has been investigated using cells from human tonsils. In tonsils, IgG-containing cells are predominant, but a certain number of IgM, IgA and IgD-containing cells are also present. By using a double staining immunofluorescent techni... | 824,142 | [
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Polychlorinated biphenyls (phenoclor and pyralene) and intestinal transport of hexoses and amino acids in mice. | 1. Using mouse everted whole small intestine 7 days after a single dose of Phenoclor DP6 (hexachlorobiphenyl) at 1.0 g kg-1 body wt, absorption of D-glucose decreased significantly, probably owing to toxic traces of pentodicholobenzofuran in the PCB preparation and not its high chlorine content. D-glucose tissue accumu... | 824,175 | [
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Morphological changes in Escherichia coli and Bacillus cereus caused by external histone. | It was found that the externally added histone changes remarkably both the surface and the internal ultrastructure of cells of Escherichia coli. The interaction of histone with surface structures results in thickening of the inner layer of the cell wall. Cytoplasm becomes condensed, contains extensive electrontransport... | 824,179 | [
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-0.1352171,
-0.3066626,
0.5635834,
0.3495997,
-0.05715878,
-0.1... |
Activity patterns in a sooty mangabey group. | Diurnal, temperature and weather influences on the activity profiles of a sooty mangabey group were compared to similar data previously reported for geladas and pigtail monkeys. Distinct behavioral profiles for each group were obtained despite the near identity of living conditions. Mangabey patterns in captivity appea... | 824,181 | [
0.08228321,
0.162603,
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0.02611373,
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0.06330812,
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0.1867953,
0.1137562,
0.0867356,
0.06762336,
0.03787435,
0.00412702... |
Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. | An ab-interno goniotomy-like operation for disinserting the ciliary muscle from the scleral spur in cynomolgus monkeys is described. Following postoperative miotic and corticosteroid treatment, the eyes did well clinically and the muscle reattached to the sclera posterior to the spur. Outflow facility and intraocular p... | 824,222 | [
-0.1985206,
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0.1366052,
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0.1203882,
0.01430606,
0.04455937,
-... |
Ribonucleotide reductase activity in ether-treated cells of Agmenellum quadruplicatum. | Ribonucleotide (cytidine 5'-diphosphate) reductase activity can be detected in situ in cells of the blue-green alga Agmenellum quadruplicatum, strain PR-6, after the cells are made permeable by treatment with ether. The Agmenellum reductase resembles the enzyme from Escherichia coli. | 824,283 | [
-0.1335542,
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0.2531303,
0.1204153,
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0.03546291,
0.24089,
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0.2476004,
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0.5731916,
0.1982342,
0.09726671,
0.... |
Delayed pituitary hormone response to LRF and TRF in patients with anorexia nervosa and with secondary amenorrhea associated with simple weight loss. | The qualitative and quantitative responses of LRF-induced LH and FSH release and TRF-induced TSH and Prolactin (PRL) release were evaluated in 21 patients with anorexia nervosa, 19 patients with secondary amenorrhea associated with simple weight loss (SWL) who did not fulfill the psychologic criteria for anorexia nervo... | 824,302 | [
0.3753393,
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0.4489636,
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0.1722226,
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0.04132852,
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0.02274379,
0.2408509,
-0.02435786,
-0.07805178... |
An animal model for experimental echocardiographic studies. | An open-chest canine model for acute experimental echocardiographic studies is described. The ultrasound transducer is placed on the exposed anterior epicardial surface, fixed in place to minimize transmitted motion or excessive pressure on the heart, and directed to record various intracardiac structures. Good recordi... | 824,315 | [
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0.2674559,
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0.1530891,
-0.0871304,
-0.1522565,... |
Intraoperative echocardiographic studies of the mitral valve: assessment of commissurotomy and repair. | Mitral echocardiograms obtained by direct application of the ultrasonic probe to the epicardial surface were compared with echocardiograms obtained by the conventional chest surface technique in 32 patients. The groups comprised 16 patients with stenosis, nine with incompetence, and seven patients with normal mitral va... | 824,316 | [
-0.01267037,
0.3502587,
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0.5683365,
-0.1102104,
-0.3444681,
... |
Sensitivity of Providence to antiseptics and disinfectants. | Seventy isolates of Providence were obtained from urinary tract infections in patients from five hospitals. They were all identified as Providence B (Providencia stuartii). A typing system was devised for these organisms based on their production of and sensitivity to bacteriophage and bacteriocins. Using this system, ... | 824,328 | [
0.1515274,
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0.1048097,
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0.05987137,
-0.34699,
0.101094,
0.01729073,
-0... |
Responses of rumen microflora to high-concentrate low-roughage diets containing whey products. | After 3 wk on a standardization ration of alfalfa hay and corn silage ad libitum and concentrate at 1 kg/3 kg milk, 15 lactating Holstein cows were fed 2.3 kg hay/day and one of five concentrate rations ad libitum for a 6-wk experiment. Cows were returned to the standardization ration after the experimental period. Con... | 824,331 | [
0.09023588,
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0.06966548,
0.4906529,
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0.13786,
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0.001011138,
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-0.01646535,
-0.0005532611,
-0.1626499,
0.2960565,
0.497293,
-0.09986... |
Prompt confirmation of Rocky Mountain spotted fever: identification of rickettsiae in skin tissues. | Rickettsia rickettsii were identifiable by the immunofluorescence technique in skin specimens obtained by biopsy on days 4 and 8 of illness from patients with Rocky Mountain spotted fever. The immunofluorescence technique is regarded as a practical means of confirming the diagnosis during the early stages of illness be... | 824,374 | [
0.1086116,
-0.07338464,
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0.1145043,
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0.03934487,
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0.2802068,
0.1869878,
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-0.09048766,
0.11218,
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0.007473868,
0.2260101,
0.06684978,
-0.0337344... |
Serogrouping of Neisseria gonorrhoeae: identification of four immunologically distinct acidic polysaccharides. | A series of population-specific acidic polysaccharides have been described that can be used as a basis for serogrouping of Neisseria gonorrhoeae. These polysaccharides have been designated Gc antigens, and four immunologically distinct types have been identified. With these purified serogroup antigens and appropriately... | 824,376 | [
-0.02085847,
0.1873636,
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-0.4013791,
0.2795778,
0.03808793,
0.02673165,
0.2725271,
-0.003820578,
-0.1... |
The effect of growth and joint formation on bristle pattern in D. melanogaster. | Dependence of bristle pattern on size and joint formation was studied for male first leg tarsi of fj (four jointed) and d (dachs) mutants in homozygotes and in mosaics resulting from X-ray induced mitotic recombination. Homozygotes have four tarsal segments, lacking a third tarsal joint in most cases. The two proximal ... | 824,401 | [
-0.1271288,
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0.1865871,
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0.2746569,
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0.1801849,
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-0.3448074,
0.0005142787,
0.210243,
0.1751025,
0.5592112,
0.1226259,
-0.0992615... |
Granular cell peripheral odontogenic fibroma. | A case of a peripheral odontogenic fibroma which contained aggregates of large granular cells is reported. These granular cells are similar to those previously described in the granular cell myoblastoma, congenital epulis and the granular cell ameloblastic fibroma. Deep extensions of the basal layer of overlying gingiv... | 824,426 | [
-0.05342156,
-0.1550075,
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0.3883649,
0.1166374,
-0.2037122,
... |
4-Hyroxyaminoquinoline-1-oxide-induced ultrastructural changes in the guinea-pig exocrine pancreas. | 4-hydroxyaminoquinoline, a carcinogen was injected into guinea-pigs intravenously in a single dose of 22-5 mg/kg. The sequential morphological changes in the exocrine cells of the pancreas were studied by electron microscopy at selected intervals between 18 and 60 hr. The earliest alterations in the acinar cells compri... | 824,428 | [
-0.010024,
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0.05584082,
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0.1973604,
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0.3492879,
-0.2945518,
0.2451945,
0.1980183,
0.1787961,
0.033436... |
Effects of intracoronary and intravenous nitroglycerin on coronary collateral function. | Previous studies have demonstrated that nitroglycerin is capable of enhancing coronary collateral function. In the present investigation, the effects of intravenous and intracoronary nitroglycerin were compared to determine whether nitroglycerin augments collateral function by a direct action on the coronary circulatio... | 824,440 | [
-0.4106812,
0.1911377,
-0.4966076,
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0.208618,
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0.1631759,
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-0.177072,
0.1909707,
-0.1789315,
0.3781003,
-0.0... |
Natriuretic effect of furosemide after inhibition of prostaglandin synthetase. | The effects of furosemide on stimulation of renin secretion and urinary sodium excretion were studied in dogs pretreated with the prostaglandin synthetase inhibitors, indomethacin and meclofenamate. Pretreatment with these drugs failed to modify the natriuretic response to furosemide but completely blocked the rise in ... | 824,442 | [
-0.2261423,
0.1292773,
0.02183228,
-0.01625292,
0.24773,
-0.416379,
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0.1084344,
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0.1331113,
-0.002140892,
0.09385435,
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0.2492747,
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0.2801729,
0.08017363,
0.1454408,
-0.3001785,
... |
The passive permeability of the skin of anuran amphibia: a comparison of frogs (Rana pipiens) and toads (Bufo marinus). | 1. Efflux of Na across dorsal skin, in vitro (bathed on both sides with Ringer solution), of frogs and toads were similar, but it was greater in ventral skin from the latter. 2. The efflux of Na declined, in both species, when the external surface of ventral, but not dorsal, skin was exposed to hyposmotic solutions wit... | 824,445 | [
0.1976423,
-0.01671459,
-0.193827,
0.1850938,
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-0.1342717,
-0.1958475,
0.002047196,
0.04654146,
-0.0492... |
Reduced 8-aminoquinoline analogues as potential antimalarial agents. | The synthesis of 1-alkyl-8-(aminoalkylamino)-6-methyl1-1,2,3,4-tetrahydroquinolines, 8-(4'-amino-1'-methylbutylamino)-6-methoxy-1-methyl1-1,2-dihydroquinoline, 5-substituted 8-(4'-amino-1'-methylbutylamino)-1-methyl-1,2-dihydroquinolines, 8-alkylamino-1-(2-N,N-diethylaminoethyl)-6-methoxy-1,2,3,4-tetrahydroquinolines, ... | 824,447 | [
-0.4065896,
0.3785366,
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0.04549941,
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0.4128114,
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0.3179103,
0.2203566,
0.1201242,
-0.05263559,
-0.... |
Peculiar artefacts after fixation with glutaraldehyde and osmium tetroxide. | Peculiar electron dense granules were observed, in otherwise well preserved structures of the heart muscle and kidney of the rat after a 5-10 min perfusion, a 2 h fixation in the modified Karnovsky solution, followed by a postfixation in Millonig buffer containing 1% OsO4. The granules appeared most frequently on membr... | 824,449 | [
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0.1866051,
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0.0836061,
0.1396528,
0.05505631,
0.08535315,
0.04484006,
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0.3397114,
0.1016264,
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-0.5183551,
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-0.2492769,
-0.2698215,
0.02561401,
0.1598512,
0.1240179,
0.4196382,
-0.06858728... |
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