title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Doping of single polymeric nanoparticles. | The oxidative doping of single poly(N-vinylcarbazole) (PVK) nanoparticles is reported in aqueous sodium perchlorate using the nanoimpact method. Complete oxidative doping of single PVK nanoparticles with a size of approximately 120 nm is demonstrated, showing for the first time a simple strategy to synthesize and chara... | 25,098,671 | [
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Update on systemic therapy of advanced non-small-cell lung cancer. | In the last decade, major progress in the treatment of advanced non-small-cell lung cancer has been made through the better understanding of the molecular biology of lung cancer, identification of new oncogene drivers and development of oncogene-directed drugs. Oncogene-directed therapies with EGFR or anaplastic lympho... | 25,098,682 | [
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[Acceptance of tinnitus: Validation of the ‛Akzeptanzfragebogen bei chronischem Tinnitus' (AFCT)]. | Tinnitus is a widely spread symptom, which is perceived chronically by approximately 10% of the population. The vast majority of the tinnitus patients doesn´t feel impaired through the ear noise, but about 5-30% of the tinnitus patient are suffering in their everyday life. Whether severe distress is experienced cannot ... | 25,098,720 | [
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Swallowing function after laryngeal cleft repair: more than just fixing the cleft. | To evaluate and describe the swallowing function in children after laryngeal cleft repair. Ten-year (2002-2012) retrospective chart review. Academic tertiary care pediatric otolaryngology practice. Records of 60 children who had surgical repair of laryngeal cleft (ages 2 weeks-14 years) and postoperative functional end... | 25,098,751 | [
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Effect of copper exposure on reproductive ability in the bank vole (Myodes glareolus). | The amount of copper in natural ecosystems is steadily increasing, due to human activities. It accumulates in plants, posing a threat to herbivores. In polluted areas the population density of small rodents is observed to be lower. The decline in rodent numbers may be caused by increased mortality or diminished fertili... | 25,098,774 | [
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Rapid evaluation of urinary retention and penile pain using point-of-care ultrasound. | We describe the case of an 18-year-old male with a history of nephrolithiasis presenting with acute urinary retention and penile pain. Point-of-care ultrasound was used to rapidly identify a urethral calculus causing obstruction of urinary outflow and allowed for expedited care. Further visualization of the kidneys gav... | 25,098,806 | [
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Plant defence suppression is mediated by a fungal sirtuin during rice infection by Magnaporthe oryzae. | Crop destruction by the hemibiotrophic rice pathogen Magnaporthe oryzae requires plant defence suppression to facilitate extensive biotrophic growth in host cells before the onset of necrosis. How this is achieved at the genetic level is not well understood. Here, we report that a M. oryzae sirtuin, MoSir2, plays an es... | 25,098,820 | [
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Appetite regulatory hormones in women with anorexia nervosa: binge-eating/purging versus restricting type. | Anorexia nervosa is a psychiatric illness characterized by low weight, disordered eating, and hallmark neuroendocrine dysfunction. Behavioral phenotypes are defined by predominant restriction or bingeing/purging; binge-eating/purging type anorexia nervosa is associated with poorer outcome. The pathophysiology underlyin... | 25,098,834 | [
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Quantitation of trans-aconitic acid in different stages of the sugar-manufacturing process. | The sugar cane industry has seen how biomass production in sugar mills would be converted to a readily available source of molecules besides sugar. Properly managed, byproducts would be transformed into a sustainable source of renewable and environmentally friendly chemical products. As a principal and more abundant or... | 25,098,840 | [
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Network reorganization of dynamic covalent polymer gels with exchangeable diarylbibenzofuranone at ambient temperature. | Reversible bonds and interactions have been utilized to build stimuli-responsive and reorganizable polymer networks that show recyclability, plasticity, and self-healing. In addition, reorganization of polymer gels at ambient temperature, such as room or body temperature, is expected to lead to several biomedical appli... | 25,098,856 | [
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Development of SPAWM: selection program for available watershed models. | A selection program for available watershed models (also known as SPAWM) was developed. Thirty-three commonly used watershed models were analyzed in depth and classified in accordance to their attributes. These attributes consist of: (1) land use; (2) event or continuous; (3) time steps; (4) water quality; (5) distribu... | 25,098,866 | [
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UV/TiO₂ photocatalytic oxidation of recalcitrant organic matter: effect of salinity and pH. | Photocatalytic oxidation processes have interest for water treatment since these processes can remove recalcitrant organic compounds and operate at mild conditions of temperature and pressure. However, performance under saline conditions present in many water resources is not well known. This study aims to explore the ... | 25,098,872 | [
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Simple design criteria and efficiency of hydrodynamic vortex separators. | Vortex separators still draw attention from specialists investigating the process of removing particles suspended in liquids. The devices are locally applied for waste water treatment in different systems - from storm waste water sewerage to water circulation in fish ponds. However, the methods for separator design pre... | 25,098,875 | [
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Update on ectodermal dysplasias clinical classification. | Monogenic genetic disorders constitute a very large group of rare conditions, each of which is defined by a characteristic combination of phenotypic features. Their enormous clinical variability and their etiological heterogeneity may result in difficulties for the establishment of a syndromic diagnosis. In this contex... | 25,098,893 | [
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Herbal tea identification using mid-infrared spectroscopy. | Herbal teas and other herbal preparations are becoming more and more popular, and it is essential to ensure their quality. Quality control methods that are simple, fast, and of low cost are needed by the producers and by inspections. Infrared spectroscopy coupled with multivariate mathematical methods has been shown to... | 25,098,931 | [
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Morphology and structure characterization of bacterial celluloses produced by different strains in agitated culture. | The influence of bacterial species/strains in agitated culture was investigated on the morphology and structure characteristics of bacterial cellulose. Komagataeibacter nataicola Y19 and Gluconacetobacter entanii ACCC10215 were inoculated in Hestrin-Schramm (HS) medium and subjected to agitated cultivation. Different k... | 25,098,972 | [
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Copper-catalyzed decarboxylative sulfonylation of α,β-unsaturated carboxylic acids. | Copper-catalyzed, ligand-promoted decarboxylative coupling of readily available α,β-unsaturated acids with sodium aryl sulfinates is presented. This method provides a new avenue for the synthesis of vinyl sulfones via a decarboxylative radical coupling strategy by employing a catalytic amount of Cu(ClO4)2·6H2O, TBHP in... | 25,098,975 | [
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Expression of podoplanin in oral premalignant and malignant lesions and its potential as a biomarker. | To analyze and compare the expression of podoplanin in normal oral tissues, leukoplakia and oral squamous cell carcinoma (OSCC) and to predict its use as a biomarker. Ninety-two formalin fixed paraffin embedded tissue samples comprising of 32 cases of leukoplakia, 50 cases of OSCCs and ten normal gingival samples. The ... | 25,098,985 | [
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Osteoporosis and periodontitis: is there a possible link? | Periodontitis and osteoporosis are two diseases found worldwide having the main characteristic of increasing intensity with age. Periodontitis is associated with resorption of the alveolar bone. Osteoporosis is characterized by bone loss leading to structural bone transformation. The association between periodontitis a... | 25,098,987 | [
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Determination of the biometric characteristics of palatine rugae patterns in Uttar Pradesh population: a cross-sectional study. | Identification is the establishment of identity of an individual. The basis of dental identification is based on the observation that no two individuals can have same dentition. Palatal rugae are irregular, asymmetric ridges of the mucous membrane extending laterally from the incisive papilla and the anterior part of t... | 25,098,990 | [
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Casting made simple using modified sprue design: an in vitro study. | Success in dental casting restorations for fixed partial dentures (FPDs) depends on the castability. Castability is described as the ability of an alloy to faithfully reproduce sharp detail and fine margins of a wax pattern. The goal of a prosthodontist is to provide the patient with restorations that fit precisely. Re... | 25,098,992 | [
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Expression of maspin in benign and malignant salivary gland tumors: an immunohistochemical study. | Maspin is a novel serine protease inhibitor (serpin) with multifaceted tumor-suppressive activities. It was originally identified in normal human breast myoepithelial cells and shows variable expression in different types of cancer cells. Maspin displays anti-metastatic properties in mammary and prostate cancer. Its ex... | 25,098,993 | [
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Atypical histiocytic granuloma: a differential to nonhealing ulcers of the oral cavity. | This is a case report of a rare clinical entity known as atypical histiocytic granuloma (AHG), which was previously grouped under a broad category known as pseudolymphoma or traumatic eosinophilic granuloma. Less than 15 cases of AHG have been reported until date. AHG poses diagnostic dilemma due to its clinical as wel... | 25,099,004 | [
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Detection of visual pursuit in patients in minimally conscious state: a matter of stimuli and visual plane? | The aim of this study was to determine whether the assessment of pursuit eye movements in patients in minimally conscious state (MCS) is influenced by the choice of the visual stimulus (study 1) and by the moving plane (study 2). Patients with MCS (MCS- and MCS+) in the acute (<1 month post-injury) or chronic (>1... | 25,099,021 | [
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Impact of oral health on physical and psychosocial dimensions: an analysis using structural equation modeling. | This study aimed to estimate the prevalence of impact of oral health conditions on physical and psychosocial dimensions among adolescents and to identify factors associated with severity of impact. The impact of oral health status was assessed by the instrument Oral Health Impact Profile (OHIP-14). The covariates were:... | 25,099,041 | [
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[Short-term impact of changes in drinking-and-driving legislation in Guadalajara and Zapopan, Jalisco, Mexico]. | The municipalities of Guadalajara and Zapopan, Jalisco State, Mexico, have participated in efforts to reduce road traffic injuries. They have participated actively in the Mexican Road Safety Initiative since 2008. As a result, in September 2010 they passed laws to reduce the legal alcohol levels for driving motor vehic... | 25,099,051 | [
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Effects of amphibian chytrid fungus exposure on American toads in the presence of an insecticide. | Abiotic factors such as pesticides may alter the impact of a pathogen on hosts, which could have implications for host-pathogen interactions and may explain variation in disease outbreaks in nature. In the present laboratory experiment, American toad (Anaxyrus americanus) metamorphs were exposed to the amphibian chytri... | 25,099,070 | [
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Measuring the improvement in health-related quality of life using King's health questionnaire in non-obese and obese patients with lower urinary tract symptoms after alpha-adrenergic medication: a preliminary study. | The efficacy of medical treatment among obese men with lower urinary tract symptoms (LUTS) has been less clear, especially regarding the improvement of QoL. We aimed to investigate the difference in efficacy and consequent satisfaction of life quality after medical treatment of male LUTS according to obesity. An 8-week... | 25,099,073 | [
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Physician preference is a major factor in management of vesicoureteral reflux. | Known factors affecting the management of vesicoureteral reflux (VUR) include reflux grade, infection frequency, age and gender. We hypothesized that provider preference is highly associated with management. Utilizing the national billing database, Faculty Practice Solutions Center, a multivariable logistic regression ... | 25,099,082 | [
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Recognizing and managing left ventricular dysfunction associated with therapeutic inhibition of the vascular endothelial growth factor signaling pathway. | Therapeutic inhibition of the vascular endothelial growth factor (VEGF) signaling pathway (VSP) is increasingly employed in the contemporary treatment of many cancer types. VSP inhibitors include the anti-VEGF monoclonal antibody (bevacizumab), soluble VEGF receptors (VEGF Trap), and small molecule tyrosine kinase inhi... | 25,099,086 | [
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Pbp2x localizes separately from Pbp2b and other peptidoglycan synthesis proteins during later stages of cell division of Streptococcus pneumoniae D39. | The relative localization patterns of class B penicillin-binding proteins Pbp2x and Pbp2b were used as positional indicators of septal and peripheral (side-wall-like) peptidoglycan (PG) synthesis, respectively, in the mid-cell regions of Streptococcus pneumoniae cells at different stages of division. We confirm that Pb... | 25,099,088 | [
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Retinal and optic nerve ischemia. | This review focuses on aspects of retinal and optic nerve ischemia that may be encountered by neurologists. Recent guidelines have emphasized the similarities between cerebral and retinal ischemia in terms of etiologic workup, acute management, and subsequent stroke risk. However, although ischemic optic neuropathies r... | 25,099,097 | [
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Papilledema and idiopathic intracranial hypertension. | Papilledema is one of the most concerning physical examination findings in neurology: it has a broad differential diagnosis of intracranial (and occasionally spinal) pathology associated with increased intracranial pressure. Papilledema impairs axoplasmic flow within the optic nerves and compresses the optic nerves ext... | 25,099,098 | [
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Higher cortical visual deficits. | This article reviews the various types of visual dysfunction that can result from lesions of the cerebral regions beyond the striate cortex. Patients with dyschromatopsia can exhibit problems with color constancy. The apperceptive form of prosopagnosia is associated with damage to posterior occipital and fusiform gyri,... | 25,099,101 | [
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Supranuclear eye movement abnormalities. | The components of the efferent ocular motor network include supranuclear, nuclear, internuclear, infranuclear, neuromuscular junction, and muscle. Within this schema, clinicians are often least acquainted with the supranuclear components; however, derangement of this system is a common cause of ocular dysmotility and d... | 25,099,104 | [
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PTEN loss in biopsy tissue predicts poor clinical outcomes in prostate cancer. | To determine whether PTEN status in prostate biopsy represents a predictor of intermediate and long-term oncological outcomes after radical prostatectomy, and whether PTEN status predicts response to androgen deprivation therapy. In a retrospective analysis of 77 men treated by radical prostatectomy who underwent diagn... | 25,099,119 | [
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Evaluating the impact of the alcohol act on off-trade alcohol sales: a natural experiment in Scotland. | A ban on multi-buy discounts of off-trade alcohol was introduced as part of the Alcohol Act in Scotland in October 2011. The aim of this study was to assess the impact of this legislation on alcohol sales, which provide the best indicator of population consumption. Interrupted time-series regression was used to assess ... | 25,099,127 | [
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Reflecting on the tensions faced by a community-based multicultural health navigator service. | The community navigator model was developed to assist four culturally and linguistically diverse communities (Sudanese, Burmese, Pacific Islander Group, Afghani) in south-east Queensland to negotiate the Australian health system and promote health. Using participatory action research, we developed the model in partners... | 25,099,133 | [
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Competing atmospheric reactions of CH2OO with SO2 and water vapour. | H2SO4 formation from the reaction CH2OO + SO2 has been measured as a function of the water vapour concentration for close to atmospheric conditions. Second-order kinetics with regard to water indicates a preferred reaction of CH2OO with the water dimer. The obtained kinetic parameters lead to the conclusion that the at... | 25,099,138 | [
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Contextual influences on nurses' decision-making in cases of physical restraint. | In order to fully understand nurses' ethical decision-making in cases of physical restraint in acute older people care, contextual influences on the process of decision-making should be clarified. What is the influence of context on nurses' decision-making process in cases of physical restraint, and what is the impact ... | 25,099,139 | [
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Microbial community structure and pharmaceuticals and personal care products removal in a membrane bioreactor seeded with aerobic granular sludge. | A process involving the use of membrane bioreactor seeded with aerobic granular sludge (GMBR) was applied to the treatment of sewage containing pharmaceuticals and personal care products (PPCPs). The removal effects of five kinds of medicines in the reactor were investigated, and the microbial communities were construc... | 25,099,174 | [
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Chlorate reduction in Shewanella algae ACDC is a recently acquired metabolism characterized by gene loss, suboptimal regulation and oxidative stress. | Previous work on respiratory chlorate reduction has biochemically identified the terminal reductase ClrABC and the chlorite detoxifying enzyme Cld. In Shewanella algae ACDC, genes encoding these enzymes reside on composite transposons whose core we refer to as the chlorate reduction composite transposon interior (CRI).... | 25,099,177 | [
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Comparative biochemical analysis of the major yolk protein in the sea urchin egg and coelomic fluid. | The major yolk protein (MYP) is localized to the egg and coelomic fluid of the adult sea urchin. While the egg-localized MYP has been extensively studied, much less is known about the coelomic fluid-localized protein. Therefore, we have conducted a comparative biochemical analysis of these proteins. Sucrose density gra... | 25,099,210 | [
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Morphine and cocaine increase serum- and glucocorticoid-inducible kinase 1 activity in the ventral tegmental area. | Drugs of abuse modulate the function and activity of the mesolimbic dopamine circuit. To identify novel mediators of drug-induced neuroadaptations in the ventral tegmental area (VTA), we performed RNA sequencing analysis on VTA samples from mice administered repeated saline, morphine, or cocaine injections. One gene th... | 25,099,208 | [
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Comparing adult users of public and private dental services in the state of Minas Gerais, Brazil. | Studying the factors associated with the use of dental services can provide the necessary knowledge to understand the reasons why individuals seek out public healthcare services and the formulation of more appropriate public policies for the present-day reality. This work was a cross-sectional epidemiological study con... | 25,099,268 | [
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Different combinations of perceptual, emotional, and cognitive factors predict three different types of delusional ideation during adolescence. | Although adolescence is a particularly sensitive period for the development of schizotypy (Walker and Bollini [Schizophr Res 54:17-23, 2002]), there has been relatively limited research on the psychological factors that specifically predict delusional beliefs during adolescence. We studied 392 school students aged 11 t... | 25,099,297 | [
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Mindfulness-based mobile applications: literature review and analysis of current features. | Interest in mindfulness has increased exponentially, particularly in the fields of psychology and medicine. The trait or state of mindfulness is significantly related to several indicators of psychological health, and mindfulness-based therapies are effective at preventing and treating many chronic diseases. Interest i... | 25,099,314 | [
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Early intervertebral disc degeneration changes in asymptomatic weightlifters assessed by t1ρ-magnetic resonance imaging. | Case-control study. To evaluate early intervertebral disc degeneration quantified by T1ρ- and T2-weighted magnetic resonance imaging (MRI) in asymptomatic weightlifters compared with a healthy control group matched for sex and age. Athletes consistently recruit or transfer high levels of repetitive forces through the s... | 25,099,319 | [
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High prevalence of occult hepatitis B virus genotype H infection among children with clinical hepatitis in west Mexico. | Studies on the prevalence of infection with hepatitis B virus (HBV) among children are scarce in Latin American countries, especially in Mexico. This study was aimed to investigate the prevalence of HBV infection, occult hepatitis B infection (OBI) and HBV genotypes among children with clinical hepatitis. In total, 215... | 25,099,333 | [
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Expression of Xylella fastidiosa RpfF in citrus disrupts signaling in Xanthomonas citri subsp. citri and thereby its virulence. | Xylella fastidiosa and Xanthomonas citri subsp. citri, that cause citrus variegated chlorosis (CVC) and citrus canker diseases, respectively, utilize diffusible signal factor (DSF) for quorum sensing. DSF, produced by RpfF, are similar fatty acids in both organisms, although a different set of genes is regulated by DSF... | 25,099,341 | [
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DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris. | Nervous system injury or disease leads to activation of glia, which govern postinjury responses in the nervous system. Axonal injury in Drosophila results in transcriptional up-regulation of the glial engulfment receptor Draper; there is extension of glial membranes to the injury site (termed activation), and then axon... | 25,099,352 | [
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Free-energy inference from partial work measurements in small systems. | Fluctuation relations (FRs) are among the few existing general results in nonequilibrium systems. Their verification requires the measurement of the total work performed on a system. Nevertheless in many cases only a partial measurement of the work is possible. Here we consider FRs in dual-trap optical tweezers where t... | 25,099,353 | [
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Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions. | Recent studies have demonstrated that thymus-derived naturally occurring CD4(+)Foxp3(+) regulatory T cells (Tregs) in human and mouse may be unstable and dysfunctional in the presence of proinflammatory cytokines. All-trans RA (atRA), the active derivative of vitamin A, has been shown to regulate Treg and T effector ce... | 25,099,355 | [
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Achievements and challenges of adoptive T cell therapy with tumor-infiltrating or blood-derived lymphocytes for metastatic melanoma: what is needed to achieve standard of care? | Adoptive cell therapy (ACT) based on autologous T cell derived either from tumor as tumor-infiltrating lymphocytes (TILs) or from peripheral blood is developing as a key area of future personalized cancer therapy. TIL-based ACT is defined as the infusion of T cells harvested from autologous fresh tumor tissues after ex... | 25,099,366 | [
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Identification and characterization of the yellow pigment synthesized by Cupriavidus sp. USMAHM13. | Microbial pigments are gaining intensive attention due to increasing awareness of the toxicity of synthetic colours. In this study, a novel polymer-producing bacterium designated as Cupriavidus sp. USMAHM13 was also found to produce yellow pigment when cultivated in nutrient broth. Various parameters such as temperatur... | 25,099,372 | [
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Identifying the 'if' for 'if-then' plans: combining implementation intentions with cue-monitoring targeting unhealthy snacking behaviour. | Implementation intentions aimed at changing unwanted habits require the identification of personally relevant cues triggering the habitual response in order to be effective. To facilitate successful implementation intention formation, in the present study, planning was combined with cue-monitoring, a novel way to gain ... | 25,099,386 | [
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[Autoimmune pancreatitis--treatment and pitfalls in diagnostics]. | Autoimmune pancreatitis (AIP) was first classified as a defined disease entity in 1995. It accounts for approximately 2 % of cases of chronic pancreatitis (western world prevalence 36-41/100,000 inhabitants) and AIP is diagnosed in 2.4 % of pancreas resection specimens. Presentation of strategies for diagnosis and trea... | 25,099,388 | [
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Reinforced active middle ear implant fixation in incus vibroplasty. | The active middle ear implant Vibrant Soundbridge® was originally designed to treat mild-to-severe sensorineural hearing losses. The floating mass transducer (FMT) is crimped onto the long incus process. The procedure is termed incus vibroplasty to distinguish from other attachment sites or stimulus modi for treating c... | 25,099,400 | [
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The Affordable Care Act: new opportunities for cardiac rehabilitation in the workplace? | Many people affected by cardiovascular disease (CVD) are working age. Employers bear a large percentage of the costs associated with CVD. Employers pay 80 times more in diagnosis and treatment than in prevention, although there is evidence that 50% to 70% of all diseases are associated with preventable health risks. As... | 25,099,406 | [
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The effectiveness of post-offer pre-placement nerve conduction screening for carpal tunnel syndrome. | We evaluated post-offer pre-placement (POPP) nerve conduction studies (NCS) for carpal tunnel syndrome (CTS), testing diagnostic yield and cost-effectiveness. A total of 1027 newly hired workers underwent baseline NCS and were followed for an average of 3.7 years for diagnosed CTS. Measures of diagnostic yield included... | 25,099,410 | [
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Beryllium Biobank 3: considerations for improving chronic beryllium disease screening. | To optimize beryllium worker screening. Beryllium-exposed persons are classified as beryllium-exposed, beryllium-sensitized (BeS), or chronic beryllium disease. Implications of defining BeS by two or more positive lymphocyte proliferation tests (LPTs) were investigated with a simple binomial model. The potential effect... | 25,099,414 | [
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A novel formulation for Neumann inflow boundary conditions in biomechanics. | Neumann boundary conditions prescribing the total momentum flux at inflow boundaries of biomechanical problems are proposed in this study. This approach enables the simultaneous application of velocity/flow rate and pressure curves at inflow boundaries. As the basic numerical method, a residual-based variational multis... | 25,099,458 | [
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K-t GRAPPA-accelerated 4D flow MRI of liver hemodynamics: influence of different acceleration factors on qualitative and quantitative assessment of blood flow. | We sought to evaluate the feasibility of k-t parallel imaging for accelerated 4D flow MRI in the hepatic vascular system by investigating the impact of different acceleration factors. k-t GRAPPA accelerated 4D flow MRI of the liver vasculature was evaluated in 16 healthy volunteers at 3T with acceleration factors R = 3... | 25,099,493 | [
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Metabolic effects of large-volume liposuction for obese healthy women: a meta-analysis of fasting insulin levels. | Obesity is increasingly frequent in our society and is associated closely with metabolic disorders. As some studies have suggested, removal of fat tissue through liposuction and dermolipectomies may be of some benefit in the improvement of metabolic indices. This article aimed to review the published literature on this... | 25,099,498 | [
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Augmentation mammoplasty/mastopexy: lessons learned from 107 aesthetic cases. | One-stage augmentation/mastopexy entails the challenge of augmenting breast volume with an implant while resecting excess skin. Although both augmenting and lifting the breast in a one-stage operation is gaining in popularity, its safety and its efficacy are still under debate and merit deeper evaluation. We retrospect... | 25,099,500 | [
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Trophic specialisation in a predatory group: the case of prey-specialised spiders (Araneae). | Predators appear to be less frequently specialised (i.e. adapted to restricted diet) on their prey than herbivores, parasites or parasitoids. Here, we critically evaluate contemporary evolutionary hypotheses that might be used to explain the evolution of specialised foraging in predators. We propose a unifying concept ... | 25,099,505 | [
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Association between non-alcoholic fatty liver disease and chronic kidney disease in population with prediabetes or diabetes. | The relationship between chronic kidney disease (CKD) and non-alcoholic fatty liver disease (NAFLD) in population with diabetes remains controversial. Our current study aimed to explore the association between NAFLD and CKD in population with prediabetes or diabetes. A cross-sectional study was conducted in Zhuhai city... | 25,099,524 | [
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Impact of 60-GHz millimeter waves and corresponding heat effect on endoplasmic reticulum stress sensor gene expression. | Emerging high data rate wireless communication systems, currently under development, will operate at millimeter waves (MMW) and specifically in the 60 GHz band for broadband short-range communications. The aim of this study was to investigate potential effects of MMW radiation on the cellular endoplasmic reticulum (ER)... | 25,099,539 | [
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Magnetic resonance imaging of pelvic floor disorders. | Physical examination alone is often inadequate for evaluation of pelvic floor dysfunction. Magnetic resonance imaging (MRI) is a robust modality that can provide high-quality anatomic and functional evaluation of the pelvic floor. Although lack of standardized technique and radiologist inexperience may be relative dete... | 25,099,563 | [
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Iterative sinc-convolution method for solving planar D-bar equation with application to EIT. | The numerical solution of D-bar integral equations is the key in inverse scattering solution of many complex problems in science and engineering including conductivity imaging. Recently, a couple of methodologies were considered for the numerical solution of D-bar integral equation, namely product integrals and multigr... | 25,099,566 | [
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Simulation of ultrasonic wave propagation in anisotropic poroelastic bone plate using hybrid spectral/finite element method. | This paper deals with the modeling of guided waves propagation in in vivo cortical long bone, which is known to be anisotropic medium with functionally graded porosity. The bone is modeled as an anisotropic poroelastic material by using Biot's theory formulated in high frequency domain. A hybrid spectral/finite element... | 25,099,567 | [
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Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages. | Inflammation triggered by infection or injury is tightly controlled by glucocorticoid hormones which signal via a dedicated transcription factor, the Glucocorticoid Receptor (GR), to regulate hundreds of genes. However, the hierarchy of transcriptional responses to GR activation and the molecular basis of their oftenti... | 25,099,603 | [
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Provision, organization and models of heart valve clinics within The United Kingdom. | Specialist clinics are recommended for the assessment and follow-up of patients with heart valve disease. We sought to identify the current provision of specialist valve clinics in UK. A database of all UK National Health Service hospitals was created. An online survey was distributed to each hospital to examine the mo... | 25,099,608 | [
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The physical properties of supramolecular peptide assemblies: from building block association to technological applications. | Bio-inspired nano-materials can be formed by the ordered assembly of elementary building blocks using recognition modules and structural elements. Among the biological sources, peptides and proteins are of special interest due to their role as major structural elements in all living systems, ranging from bacteria to hu... | 25,099,656 | [
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Chemosensitivity predicted by BluePrint 80-gene functional subtype and MammaPrint in the Prospective Neoadjuvant Breast Registry Symphony Trial (NBRST). | The purpose of the NBRST study is to compare a multigene classifier to conventional immunohistochemistry (IHC)/fluorescence in situ hybridization (FISH) subtyping to predict chemosensitivity as defined by pathological complete response (pCR) or endocrine sensitivity as defined by partial response. The study includes wo... | 25,099,655 | [
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Translational research in immune and inflammatory diseases; what are the challenges, expected advances, and innovative therapies? | Despite very different aetiologies and clinical expressions, advancing knowledge in the physiopathology and treatment of immune and inflammatory diseases (IID) prompts us to consider them as a whole. These are chronic, often incapacitating and painful illnesses that progress and destroy organs. Management by discipline... | 25,099,671 | [
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Hospitals caring for rural Aboriginal patients: holding response and denial. | To investigate how policy requiring cultural respect and attention to health equity is implemented in the care of rural and remote Aboriginal people in city hospitals. Interviews with 26 staff in public hospitals in Adelaide, South Australia, were analysed (using a framework based on cultural competence) to identify th... | 25,099,681 | [
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Above 5 cm, size does not matter anymore in patients with hepatocellular carcinoma. | Solitary hepatocellular carcinoma (HCC) is a good candidate for surgical resection. However, the significance of the size of the tumor in solitary HCC remains unclear. The aim of this study was to evaluate the impact of tumor size on overall and recurrence-free survival of patients with solitary HCC. We retrospectively... | 25,099,682 | [
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Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries. | The activation of the Pi3k-Akt1-FOXO pathway seems to be involved in the extended longevity observed in growth hormone receptor/growth hormone binding protein knockout (GHRKO) mice and is related to the growth of primordial ovarian follicles. The aim of this work was to measure the expression of genes in the ovaries of... | 25,099,774 | [
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BreathSens: A Continuous On-Bed Respiratory Monitoring System With Torso Localization Using an Unobtrusive Pressure Sensing Array. | The ability to continuously monitor respiration rates of patients in homecare or in clinics is an important goal. Past research showed that monitoring patient breathing can lower the associated mortality rates for long-term bedridden patients. Nowadays, in-bed sensors consisting of pressure sensitive arrays are unobtru... | 25,099,893 | [
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Origins and suppression of oscillations in a computational model of Parkinson's disease. | Efficacy of deep brain stimulation (DBS) for motor signs of Parkinson's disease (PD) depends in part on post-operative programming of stimulus parameters. There is a need for a systematic approach to tuning parameters based on patient physiology. We used a physiologically realistic computational model of the basal gang... | 25,099,916 | [
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Dynamic role of the intramolecular hydrogen bonding in nonadiabatic chemistry revealed in the UV photodissociation reactions of 2-fluorothiophenol and 2-chlorothiophenol. | The dynamic interplay between the intramolecular hydrogen bonding and intramolecular vibrational redistribution is found to be critical in nonadiabatic reaction dynamics. Herein, it has been demonstrated that the molecular planarity, directed by the intramolecular hydrogen bonding, plays an important role in the nonadi... | 25,099,919 | [
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MOMMOP: multiobjective optimization for locating multiple optimal solutions of multimodal optimization problems. | In the field of evolutionary computation, there has been a growing interest in applying evolutionary algorithms to solve multimodal optimization problems (MMOPs). Due to the fact that an MMOP involves multiple optimal solutions, many niching methods have been suggested and incorporated into evolutionary algorithms for ... | 25,099,966 | [
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0.01630384,
-0.1675739,
0.1075915,
-0.07401861,
-0.1688943,
-0.2172694,
0.1827328,
0.02470678,... |
Solid-state reaction synthesis of two-dimensional CuGaSe2 nanosheets for high performance photodetectors. | CuGaSe2 is an important non-layered I-III-VI2 compound with superior optical properties. In this work, monocrystal two-dimensional (2D) CuGaSe2 nanosheets were successfully synthesized via a simple solid-state reaction. The electronic and optoelectronic properties of photodetectors based on 2D CuGaSe2 nanosheets were i... | 25,099,970 | [
-0.2156301,
-0.240375,
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0.2770033,
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0.1447137,
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... |
Circahoralian (ultradian) metabolic rhythms. | This review presents data concerning metabolic rhythms with periods close to one hour (20 to 120 min): their occurrence, biochemical organization, nature, and significance for adaptations and age-related changes of cells and organs. Circahoralian (ultradian) rhythms have been detected for cell mass and size, protein sy... | 25,100,006 | [
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0.1429917,
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0.1851683,
-0.09164546,... |
HMGA1 is a new target of miR-195 involving isoprenaline-induced cardiomyocyte hypertrophy. | Emerging data have shown that microRNAs (miRNAs) have important functions in the processes of cardiac hypertrophy and heart failure that occur during the postnatal period. Cardiac overexpression of miR-195 results in pathological cardiac growth and heart failure in transgenic mice. In the present study, we analyzed the... | 25,100,012 | [
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... |
Regulation of Endoplasmic Reticulum-Associated Protein Degradation (ERAD) by Ubiquitin. | Quality control of protein folding inside the endoplasmic reticulum (ER) includes chaperone-mediated assistance in folding and the selective targeting of terminally misfolded species to a pathway called ER-associated protein degradation, or simply ERAD. Once selected for ERAD, substrates will be transported (back) into... | 25,100,021 | [
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... |
Illness and treatment perceptions of patients with chronic low back pain: characteristics and relation to individual, disease and interaction variables. | The significance of various cognitive and psychosocial factors in the development, progression and persistence of chronic low back pain (CLBP) is well demonstrated. However, only a few studies have addressed CLBP patients' cognitive representations or beliefs about their disease and its treatment. The present study aim... | 25,100,026 | [
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... |
Populus GT43 family members group into distinct sets required for primary and secondary wall xylan biosynthesis and include useful promoters for wood modification. | The plant GT43 protein family includes xylosyltransferases that are known to be required for xylan backbone biosynthesis, but have incompletely understood specificities. RT-qPCR and histochemical (GUS) analyses of expression patterns of GT43 members in hybrid aspen, reported here, revealed that three clades of the fami... | 25,100,045 | [
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0.3717279,
0.1599695,
0.43793,
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0.12712... |
Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload. | The regulatory axis between the iron hormone hepcidin and its receptor, the iron exporter ferroportin (FPN), is central to iron homeostasis. Mutations preventing hepcidin-mediated degradation of FPN cause systemic iron overload. We have introduced a point mutation (C326S) into the murine Fpn locus, resembling human her... | 25,100,063 | [
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0.2290399,
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0.275651,
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Confined quest for continuity: the categorical versus continuous nature of attachment. | The use of the Adult Attachment Interview (AAI) in the NICHD Study of Early Child Care and Youth Development (NICHD SECCYD) is a major contribution to the field. The core of the current monograph pertains to psychometrics (dimensional vs. categorical assessment) of the AAI and continuity of attachment over time. We arg... | 25,100,096 | [
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0.03669135,
0.283419,
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0.4046568,
0.2129057,
0.270652... |
Time trends in adolescent sexual behaviour in Italy. | Background There has been little research investigating sexual health in Italy. The aim of the present study was to present time trends over 8 years in sexual behaviour among adolescents. This study is part of the Health Behaviour in School-aged Children study (sample: 3983 adolescents aged 15 years; 51.9% girls). Meas... | 25,100,103 | [
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0.1712749,
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0.2217938,
0.5882624,
0.4457165,
-0.03788417,... |
Effects of probiotic therapy on hepatic encephalopathy in patients with liver cirrhosis: an updated meta-analysis of six randomized controlled trials. | Liver cirrhotic patients with hepatic encephalopathy have poor prognosis. Probiotics alter the intestinal microbiota and reduce the production of ammonia. We conducted a meta-analysis about the role of probiotics on liver cirrhotic patients with hepatic encephalopathy. We collected the relevant literatures up to Februa... | 25,100,119 | [
-0.08238244,
0.06324525,
0.1726532,
0.1915778,
0.001375165,
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0.2057132,
0.1473114,
0.5148572,
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0.3043952,
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0.06347521,
-0.7029756,
0.3943561,
-0.1959798,... |
Pancreaticoduodenectomy and pancreaticoduodenectomy combined with superior mesenteric-portal vein resection for elderly cancer patients. | There is an increasing frequency of pancreaticoduodenectomy (PD) and PD with superior mesenteric-portal vein (SMPV) resection in elderly cancer patients. The study aimed to investigate the safety and the survival benefits of PD and PD with SMPV resection in patients under or over 70 years of age. We divided 296 patient... | 25,100,129 | [
0.1418844,
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0.4143483,
0.3170846,
0.2491418,
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0.1584207,
-0.04719415,
... |
Are clinical trials with mesenchymal stem/progenitor cells too far ahead of the science? Lessons from experimental hematology. | The cells referred to as mesenchymal stem/progenitor cells (MSCs) are currently being used to treat thousands of patients with diseases of essentially all the organs and tissues of the body. Strikingly positive results have been reported in some patients, but there have been few prospective controlled studies. Also, th... | 25,100,155 | [
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0.1033205,
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0.4440994,
0.2552527,
0.190445,
-0.121617... |
Preferred health resources and use of social media to obtain health and depression information by adolescent mothers. | Little is known about how adolescent mothers use social media and the Internet, especially to access health information. In this cross-sectional, descriptive study, adolescent mothers were recruited from an academic medical center after the birth of their child (n = 94) or from a state-funded, home visitation program d... | 25,100,157 | [
-0.2069331,
0.09616416,
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0.3569131,
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0.1759736,
0.4563452,
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... |
Dose-dependent protective effect of lithium chloride on retinal ganglion cells is interrelated with an upregulated intraretinal BDNF after optic nerve transection in adult rats. | Neuroprotection of lithium for axotomized retinal ganglion cells (RGCs) is attributed to upregulated intraretinal Bcl-2. As lithium also upregulates brain-derived neurotrophic factor (BDNF) which can rescue axotomized RGCs, it is hypothesized that lithium could protect RGCs through BDNF. This study investigated this hy... | 25,100,168 | [
-0.1184924,
-0.0576449,
-0.3627113,
-0.2351886,
0.1636052,
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0.254806,
0.1530256,
0.01674995,
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0.1670155,
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0.01420844,
0.3899054,
0.2106482,
... |
Age dependent changes in cartilage matrix, subchondral bone mass, and estradiol levels in blood serum, in naturally occurring osteoarthritis in Guinea pigs. | The Dunkin Hartley (DH) guinea pig is a widely used naturally occurring osteoarthritis model. The aim of this study was to provide detailed evidence of age-related changes in articular cartilage, subchondral bone mineral density, and estradiol levels. We studied the female Dunkin Hartley guinea pigs at 1, 3, 6, 9, and ... | 25,100,170 | [
0.1533315,
0.01422888,
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0.2641961,
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0.1159118,
0.1386978,
0.2825747,
0.2059916,
0.3621343,
-0.2652272,
-... |
Techniques for diagnosing osteoporosis: a systematic review of cost-effectiveness studies. | The study question was whether dual-energy X-ray absorptiometry (DXA) alone is more cost-effective for identifying postmenopausal women with osteoporosis than a two-step procedure with quantitative ultrasound sonography (QUS) plus DXA. To answer this question, a systematic review was performed. Electronic databases (Pu... | 25,100,174 | [
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0.1379823,
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0.... |
Mid-term patency of the inverted left internal thoracic artery conduit. | In order to expand the revascularization of the left anterior descending coronary artery, we have applied the inverted left internal thoracic artery (left internal thoracic artery [LITA] transected near its origin, thus supplied by retrograde flow from superior epigastric and musculophrenic arteries) in carefully selec... | 25,100,203 | [
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0.07134759,
-0.1827185,
-0.2206641,
0.3204941,
0.255752,
-0.245037,
... |
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