title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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New aspects of modern endoscopy. | The prognosis for patients with malignancies of the gastrointestinal-tract is strictly dependent on early detection of premalignant and malignant lesions. However, small, flat or depressed neoplastic lesions remain difficult to detect with these technologies thereby limiting their value for polyp and cancer screening. ... | 25,132,916 | [
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Esophageal cancer management controversies: Radiation oncology point of view. | Esophageal cancer treatment has evolved from single modality to trimodality therapy. There are some controversies of the role, target volumes and dose of radiotherapy (RT) in the literature over decades. The present review focuses primarily on RT as part of the treatment modalities, and highlight on the RT volume and i... | 25,132,924 | [
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Matrix Degradative Enzymes and Their Inhibitors during Annular Inflammation: Initial Step of Symptomatic Intervertebral Disc Degeneration. | Symptomatic disc degeneration develops from inflammatory reactions in the annulus fibrosus (AF). Although inflammatory mediators during annular inflammation have been studied, the roles of matrix metalloproteinases (MMPs) and their inhibitors have not been fully elucidated. In this study, we evaluated the production of... | 25,132,928 | [
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Post-traumatic cerebral infarction following low-energy penetrating craniocerebral injury caused by a nail. | Post-traumatic cerebral infarction (PTCI) is a secondary insult which causes global cerebral hypoxia or hypoperfusion after traumatic brain injury, and carries a remarkable high mortality rate. PTCI is usually caused by blunt brain injury with gross hematoma and/or brain herniation. Herein, we present the case of a 91-... | 25,132,939 | [
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Recent trends in airway management: we are not ready to give up fiberoptic endoscopy. | The purpose of this correspondence is to discuss recent findings related to current trends in airway management and to discuss the utilization rates of video laryngoscopes versus traditional techniques in USA, UK, and Canada. To highlight the increased use of video laryngoscopes in difficult airway situations, data on ... | 25,132,963 | [
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Indications and outcomes in adult lung transplantation. | Lung transplantation (LTx) is a treatment option for end-stage lung disease that would be otherwise fatal for specific patient populations. The most common indications for LTx in adults remain to be chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, cystic fibrosis, alpha-1 antitrypsin deficiency, an... | 25,132,968 | [
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Carcinoma buccal mucosa underlying a giant cutaneous horn: a case report and review of the literature. | Cutaneous horn is a conical, dense, and hyperkeratotic protrusion that often appears similar to the horn of an animal. Giant cutaneous horns are rare; no incidence or prevalence has been reported. The significance of cutaneous horns is that they occur in association with, or as a response to, a wide variety of underlyi... | 25,133,002 | [
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Role of Toll-like receptors in Helicobacter pylori infection and immunity. | The gram-negative bacterium Helicobacter pylori (H. pylori) infects the stomachs of approximately half of the world's population. Although infection induces an immune response that contributes to chronic gastric inflammation, the response is not sufficient to eliminate the bacterium. H. pylori infection causes peptic u... | 25,133,016 | [
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Molecular mechanisms of alcohol associated pancreatitis. | Alcohol abuse is commonly associated with the development of both acute and chronic pancreatitis. Despite this close association, the fact that only a small percentage of human beings who abuse alcohol develop pancreatitis indicates that alcohol abuse alone is not sufficient to initiate clinical pancreatitis. This cont... | 25,133,017 | [
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Review to better understand the macroscopic subtypes and histogenesis of intrahepatic cholangiocarcinoma. | Intrahepatic cholangiocarcinoma is macroscopically classified into three subtypes, mass-forming-type, periductal infiltrating-type, and intraductal growth-type. Each subtype should be preoperatively differentiated to perform the valid surgical resection. Recent researches have revealed the clinical, radiologic, pathobi... | 25,133,021 | [
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Epidemiological studies of esophageal cancer in the era of genome-wide association studies. | Esophageal cancer (EC) caused about 395000 deaths in 2010. China has the most cases of EC and EC is the fourth leading cause of cancer death in China. Esophageal squamous cell carcinoma (ESCC) is the predominant histologic type (90%-95%), while the incidence of esophageal adenocarcinoma (EAC) remains extremely low in C... | 25,133,033 | [
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Visceral hypersensitivity and electromechanical dysfunction as therapeutic targets in pediatric functional dyspepsia. | Functional gastrointestinal disorders (FGID) are common clinical syndromes diagnosed in the absence of biochemical, structural, or metabolic abnormalities. They account for significant morbidity and health care expenditures and are identifiable across variable age, geography, and culture. Etiology of abdominal pain ass... | 25,133,041 | [
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Negative rumor: contagion of a psychiatric department. | Over the past few decades, a sizable body of literature on the effects of rumors and gossip has emerged. Addressing rumors in the workplace is an important subject, as rumors have a direct impact on the quality of the work environment and also on the productivity and creativity of the employees. To date, little has bee... | 25,133,051 | [
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A survey of patients' knowledge about lithium therapy in the elderly. | Lithium is commonly used in the treatment of various psychiatric disorders. It has a narrow therapeutic range and a mortality rate of 9% in patients intoxicated during maintenance therapy. Therefore, for lithium to be prescribed safely, clinicians must ensure that patients are aware of features of lithium toxicity. We ... | 25,133,060 | [
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Acute interventions and referral of patients with bipolar disorder by the psychiatric consultation liaison service in a general hospital in Germany: a retrospective analysis. | To investigate the population of bipolar patients in a general hospital in Germany who required treatment by a consultant psychiatrist. A retrospective analysis was conducted of the clinical records of 47 patients diagnosed with bipolar disorder (DSM-IV-TR criteria) who were treated by a consultant psychiatrist between... | 25,133,062 | [
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Effect of ankle braces on lower extremity muscle activation during functional exercises in participants with chronic ankle instability. | Ankle bracing and rehabilitation are common methods to reduce the rate of recurrent ankle sprain in participants with chronic ankle instability (CAI). CAI participants utilize less muscle activity when performing functional exercises compared to healthy controls. The effect of ankle braces on muscle activity during fun... | 25,133,076 | [
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A characterization of Chover-type law of iterated logarithm. | Let 0 < α ≤ 2 and - ∞ <β <∞. Let {X n ;n ≥ 1} be a sequence of independent copies of a real-valued random variable X and set S n = X 1+⋯+X n , n ≥ 1. We say X satisfies the (α,β)-Chover-type law of the iterated logarithm (and write X∈C T L I L(α,β)) if [Formula: see text] almost surely. This paper is devoted t... | 25,133,089 | [
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Equipment-based image-enhanced endoscopy for differentiating colorectal polyps. | The use of colonoscopy for the screening and surveillance of colorectal cancer has increased. However, the miss rate of advanced colorectal neoplasm is known to be 2% to 6%, which could be affected by the image intensity of colorectal lesions. Image-enhanced endoscopy (IEE) is capable of highlighting lesions, which can... | 25,133,120 | [
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Randomized controlled clinical trial of oral health-related quality of life in patients wearing conventional and self-ligating brackets. | The aim of this randomized controlled clinical trial was to compare oral health-related quality of life (OHRQoL) of patients treated with conventional, active self-ligating (ASL), and passive self-ligating (PSL) brackets in different therapeutic phases. Sixty patients (mean age 18.3 years; 29 males and 31 females) requ... | 25,133,131 | [
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Treatment and retention of relapsed anterior open-bite with low tongue posture and tongue-tie: A 10-year follow-up. | The purpose of the current report is to present 6-year long-term stability and 10-year follow-up data for an adult patient who was treated with a tongue elevator for relapsed anterior open-bite. The 19-year-old male patient presented with the chief complaint of difficulty in chewing his food. Collectively, clinical and... | 25,133,135 | [
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Prucalopride-associated acute tubular necrosis. | We report the first case of acute renal failure secondary to prucalopride, a novel agent for the treatment of chronic constipation. The 75 years old male patient was initiated on prucalopride after many failed treatments for constipation following a Whipple's procedure for pancreatic cancer. Within four months of treat... | 25,133,152 | [
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Rare large homozygous CFTR gene deletion in an Iranian patient with cystic fibrosis. | Cystic fibrosis, a common autosomal recessive genetic disorder among Caucasians, is caused by defects in the transmembrane conductance regulatory (CFTR) gene. The analysis of CFTR gene mutations is useful to better characterize the disease, and for preconceptional screening, prenatal and preimplantation genetic diagnos... | 25,133,155 | [
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Factors associated with spontaneous clearance of hepatitis C virus in Chinese population. | Hepatitis C virus (HCV) infections spontaneously clear in approximately 15-45% of infected individuals. Factors which influence spontaneous HCV clearance remain to be identified. The purpose of the present study was to identify variables associated with spontaneous HCV clearance in a referred population of Chinese pati... | 25,133,165 | [
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Anti-inflammatory effect and mechanism of the green fruit extract of Solanum integrifolium Poir. | The green fruit of Solanum integrifolium Poir. has been used traditionally as an anti-inflammatory and analgesic remedy in Taiwanese aboriginal medicine. The goal of this study is to evaluate the anti-inflammatory activity and mechanism of the green fruit extract of S. integrifolium. A bioactivity-guided fractionation ... | 25,133,186 | [
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Activation effects of polysaccharides of Flammulina velutipes mycorrhizae on the T lymphocyte immune function. | Flammulina velutipes mycorrhizae have increasingly been produced with increasing of F. velutipes production. A mouse model was thus used to examine potential effect of F. velutipes mycorrhizae on the immune function. Fifty female Wistar mice (5-weeks-old) weighed 15-20 g were randomly allocated into five groups. Polysa... | 25,133,194 | [
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Malware analysis using visualized image matrices. | This paper proposes a novel malware visual analysis method that contains not only a visualization method to convert binary files into images, but also a similarity calculation method between these images. The proposed method generates RGB-colored pixels on image matrices using the opcode sequences extracted from malwar... | 25,133,202 | [
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Bird diversity and distribution in relation to urban landscape types in northern Rwanda. | Using the point count method, linear mixed models, Shannon's diversity index, and Bray-Curtis cluster analysis, we conducted a study of the effect of urban fabric layout on bird diversity and distribution in northern Rwanda. The results showed a significant effect of city landscapes on bird richness and relative abunda... | 25,133,203 | [
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Flavonoids in Juglans regia L. leaves and evaluation of in vitro antioxidant activity via intracellular and chemical methods. | Flavonoids are rich in Juglans regia L. leaves. They have potent antioxidant properties, which have been related to regulating immune function and enhancing anticancer activity. Herein, qualitative and quantitative determination of flavonoids from J. regia leaves was carried out using high performance liquid chromatogr... | 25,133,218 | [
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Prediction of the reference evapotranspiration using a chaotic approach. | Evapotranspiration is one of the most important hydrological variables in the context of water resources management. An attempt was made to understand and predict the dynamics of reference evapotranspiration from a nonlinear dynamical perspective in this study. The reference evapotranspiration data was calculated using... | 25,133,221 | [
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A memristive hyperchaotic system without equilibrium. | A new memristive system is presented in this paper. The peculiarity of the model is that it does not display any equilibria and exhibits periodic, chaotic, and also hyperchaotic dynamics in a particular range of the parameters space. The behavior of the proposed system is investigated through numerical simulations, suc... | 25,133,225 | [
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Simple BiCMOS CCCTA design and resistorless analog function realization. | The simple realization of the current-controlled conveyor transconductance amplifier (CCCTA) in BiCMOS technology is introduced. The proposed BiCMOS CCCTA realization is based on the use of differential pair and basic current mirror, which results in simple structure. Its characteristics, that is, parasitic resistance ... | 25,133,230 | [
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Dynamic finite element analysis of mobile bearing type knee prosthesis under deep flexional motion. | The primary objective of this study is to distinguish between mobile bearing and fixed bearing posterior stabilized knee prostheses in the mechanics performance using the finite element simulation. Quantifying the relative mechanics attributes and survivorship between the mobile bearing and the fixed bearing prosthesis... | 25,133,247 | [
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Structural health monitoring of civil infrastructure using optical fiber sensing technology: a comprehensive review. | In the last two decades, a significant number of innovative sensing systems based on optical fiber sensors have been exploited in the engineering community due to their inherent distinctive advantages such as small size, light weight, immunity to electromagnetic interference (EMI) and corrosion, and embedding capabilit... | 25,133,250 | [
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Method to eliminate flux linkage DC component in load transformer for static transfer switch. | Many industrial and commercial sensitive loads are subject to the voltage sags and interruptions. The static transfer switch (STS) based on the thyristors is applied to improve the power quality and reliability. However, the transfer will result in severe inrush current in the load transformer, because of the DC compon... | 25,133,255 | [
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On the generalization of Lehmer problem and high-dimension Kloosterman sums. | For any fixed integer k ≥ 2 and integer r with (r, p) = 1, it is clear that there exist k integers 1 ≤ a i ≤ p - 1(i = 1, 2, …, k) such that a 1 a 2 ⋯ a k ≡ r mod p. Let N(k, r; p) denote the number of all (a 1, a 2, ⋯ a k ) such that a 1 a 2 ⋯ a k ≡ r mod p and 2†(a 1 + a 2 + ⋯ + a k ). In this paper, we will use the ... | 25,133,256 | [
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Feasibility of using phase change materials to control the heat of hydration in massive concrete structures. | This paper presents experimental results that can be applied to select a possible phase change material (PCM), such as a latent heat material (LHM), to control the hydration heat in mass concrete structures. Five experimental tests (microconduction, simplified adiabatic temperature rise, heat, and compressive strength ... | 25,133,259 | [
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The laws of natural deduction in inference by DNA computer. | We present a DNA-based implementation of reaction system with molecules encoding elements of the propositional logic, that is, propositions and formulas. The protocol can perform inference steps using, for example, modus ponens and modus tollens rules and de Morgan's laws. The set of the implemented operations allows f... | 25,133,261 | [
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Low power upconversion mixer for medical remote sensing. | This work presents the design of a low power upconversion mixer adapted in medical remote sensing such as wireless endoscopy application. The proposed upconversion mixer operates in ISM band of 433 MHz. With the carrier power of -5 dBm, the proposed mixer has an output inferred 1 dB compression point of -0.5 dBm with a... | 25,133,266 | [
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[Cardiovascular magnetic resonance imaging in patients with acute chest pain]. | Acute chest pain is a common reason for presentation to the emergency department. It can be caused by a wide variety of diseases, some of which are potentially lethal, so it must be diagnosed quickly. The rise of computed tomography to evaluate patients with acute chest pain is noteworthy. However, computed tomography ... | 25,133,284 | [
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Comparison of oxidation resistance of UHMWPE and POM in H2O2 solution from ReaxFF reactive molecular dynamics simulations. | The oxidation mechanism of ultra-high-molecular-weight polyethylene (UHMWPE) and polyoxymethylene (POM) in hydrogen peroxide solution was investigated by molecular dynamics (MD) simulations via reactive force field (ReaxFF) method. MD results from ReaxFF suggested that UHMWPE provided better antioxidation activity at h... | 25,133,290 | [
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Peroxides as "switches" of dialkyl H-phosphonate: two mild and metal-free methods for preparation of 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates. | Two mild and metal-free methods for the preparation of two kinds of important benzothiazole derivatives, 2-acylbenzothiazoles and dialkyl benzothiazol-2-ylphosphonates, respectively, were developed. The dialkyl H-phosphonate (RO)2P(O)H exists in equilibrium with its tautomer dialkyl phosphite (RO)2POH. TBHP triggered α... | 25,133,294 | [
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Discovery of a highly selective caspase-3 substrate for imaging live cells. | Caspases are a family of cysteine proteases that are well-known for their roles in apoptosis and inflammation. Recent studies provide evidence that caspases are also integral to many additional cellular processes, such as differentiation and proliferation. Likewise, aberrant caspase activity has been implicated in the ... | 25,133,295 | [
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Families with children with medical complexity and self-management of care: a systematic review of the literature. | This review analyzes the quantitative literature on children with medical complexity (CMC). Using the Pediatric Self-Management Model, evidence is summarized into facilitators and barriers to self-management. Current quantitative research focuses on the caregiver burden in families with CMC. A model for social work wit... | 25,133,298 | [
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Screening, testing, and reporting for drug and alcohol use on labor and delivery: a survey of Maryland birthing hospitals. | Recent amendments to the Child Abuse Prevention and Treatment Act tie the receipt of federal block grants to mandatory reporting of substance-exposed newborns. To determine rates of screening, testing, and reporting of drug and alcohol use at the time of delivery, we administered a telephone survey of nursing managers ... | 25,133,299 | [
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Efficacy and day 7 plasma piperaquine concentrations in African children treated for uncomplicated malaria with dihydroartemisinin-piperaquine. | One promising new Artemisinin-based combination therapies (ACTs) is dihydroartemisinin-piperaquine (DHA-PQ). However, the pharmacokinetics of piperaquine and the relationship between drug levels and clinical efficacy are incompletely characterized, particularly in children. We performed a single-arm open-label trial in... | 25,133,389 | [
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MiR-152 may silence translation of CaMK II and induce spontaneous immune tolerance in mouse liver transplantation. | Spontaneous immune tolerance in mouse liver transplantation has always been a hotspot in transplantation-immune research. Recent studies revealed that regulatory T cells (Tregs), hepatic satellite cells and Kupffer cells play a potential role in spontaneous immune tolerance, however the precise mechanism of spontaneous... | 25,133,393 | [
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Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model. | Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has re-emerged globally. Causes for the re-emergence of pertussis include limited duration of protection conferred by acellular pertussis vaccines (aP) and pathogen a... | 25,133,400 | [
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Chinese American immigrant parents' emotional expression in the family: Relations with parents' cultural orientations and children's emotion-related regulation. | The present study examined 2 measures of Chinese American immigrant parents' emotional expression in the family context: self-reported emotional expressivity and observed emotional expression during a parent-child interaction task. Path analyses were conducted to examine the concurrent associations between measures of ... | 25,133,412 | [
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Why does placement of persons with Alzheimer's disease into long-term care improve caregivers' well-being? Examination of psychological mediators. | Caregiving for individuals with Alzheimer's disease is associated with chronic stress and elevated symptoms of depression. Placement of the care receiver (CR) into a long-term care setting may be associated with improved caregiver well-being; however, the psychological mechanisms underlying this relationship are unclea... | 25,133,414 | [
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PAX7 expression defines germline stem cells in the adult testis. | Spermatogenesis is a complex, multistep process that maintains male fertility and is sustained by rare germline stem cells. Spermatogenic progression begins with spermatogonia, populations of which express distinct markers. The identity of the spermatogonial stem cell population in the undisturbed testis is controversi... | 25,133,429 | [
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Actinomycotic mastoiditis complicated by sigmoid sinus thrombosis and labyrinthine fistula. | Actinomyces is a rare pathogen that can be the cause of infections in the digestive and urinary tracts, skin, genitalia, and lungs, which generally have an indolent clinical course. However, in some cases these can be locally destructive and become generalized infections. Actinomyces has been previously implicated in i... | 25,133,452 | [
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Identification and functional analysis of pheromone and receptor genes in the B3 mating locus of Pleurotus eryngii. | Pleurotus eryngii has recently become a major cultivated mushroom; it uses tetrapolar heterothallism as a part of its reproductive process. Sexual development progresses only when the A and B mating types are compatible. Such mating incompatibility occasionally limits the efficiency of breeding programs in which crossi... | 25,133,513 | [
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Surface coating mediated swelling and fracture of silicon nanowires during lithiation. | Surface passivation of silicon anodes is an appealing design strategy for the development of reliable, high-capacity lithium-ion batteries. However, the structural stability of the coating layer and its influence on the lithiation process remain largely unclear. Herein, we show that surface coating mediates the swellin... | 25,133,525 | [
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Mimosa (Mimosa caesalpiniifolia) prevents oxidative DNA damage induced by cadmium exposure in Wistar rats. | The Mimosa (Mimosa caesalpiniifolia) is a plant native from South America; it is used in the traditional medicine systems for treating bacterial, fungal, parasitic and inflammatory conditions. The aim of this study was to evaluate the antigenotoxic and antioxidant activities induced by mimosa (M. caesalpiniifolia) in m... | 25,133,553 | [
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[The relationship between the temperature increase caused by phacoemulsification and the damage to the corneal endothelium]. | Endothelial cell damage can be found after a phacoemulsification. The reason for this cell damage is not yet known. The temperature rise inside the anterior chamber during the emulsification of the lens is considered as a potential damage mechanism. The aim of this study was to investigate the relationship between the ... | 25,133,560 | [
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Next-generation sequencing of colorectal cancers in chinese: identification of a recurrent frame-shift and gain-of-function Indel mutation in the TFDP1 gene. | Abstract Re-sequencing of target genes is a highly effective approach for identifying mutations in cancers. Mutations, including indels (insertions, deletions, and the combination of the two), play important roles in carcinogenesis. Combining genomic DNA capture using high-density oligonucleotide microarrays (NimbleGen... | 25,133,581 | [
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Reproducibility and consistency of proteomic experiments on natural populations of a non-model aquatic insect. | Population proteomics has a great potential to address evolutionary and ecological questions, but its use in wild populations of non-model organisms is hampered by uncontrolled sources of variation. Here we compare the response to temperature extremes of two geographically distant populations of a diving beetle species... | 25,133,588 | [
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Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles. | For systemic delivery of siRNA to solid tumors, a size-regulated and reversibly stabilized nanoarchitecture was constructed by using a 20 kDa siRNA-loaded unimer polyion complex (uPIC) and 20 nm gold nanoparticle (AuNP). The uPIC was selectively prepared by charge-matched polyionic complexation of a poly(ethylene glyco... | 25,133,608 | [
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Targeted rehabilitation after extracellular matrix scaffold transplantation for the treatment of volumetric muscle loss. | Rehabilitation therapy is an important aspect of recovery after volumetric muscle loss. However, the traditional rehabilitation approach involves a period of rest and passive loading followed by gradual active loading. Extracellular matrix is a naturally occurring material consisting of structural proteins that provide... | 25,133,624 | [
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The longitudinal impact of intimate partner aggression and relationship status on women's physical health and depression symptoms. | Intimate partner aggression (IPA) has many detrimental effects, particularly among young women. The present study examined the longitudinal effects of IPA victimization and relationship status on physical health and depression symptoms in a sample of 375 community women between the ages of 18 and 25 years. All variable... | 25,133,642 | [
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PEGylation of concanavalin A to improve its stability for an in vivo glucose sensing assay. | Competitive binding assays utilizing concanavalin A (ConA) have the potential to be the basis of improved continuous glucose monitoring devices. However, the efficacy and lifetime of these assays have been limited, in part, by ConA's instability due to its thermal denaturation in the physiological environment (37 °C, p... | 25,133,655 | [
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Maternal and umbilical cord copeptin levels in pregnancies complicated by fetal growth restriction. | The aim of this study was to compare maternal and fetal serum copeptin concentrations in pregnancies complicated by isolated fetal growth restriction (FGR), and uncomplicated pregnancies, and to investigate relationships between copeptin levels and clinical parameters. Maternal and fetal serum copeptin levels were meas... | 25,133,666 | [
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Lithium potential variations for metastable materials: case study of nanocrystalline and amorphous LiFePO4. | Much attention has been paid to metastable materials in the lithium battery field, especially to nanocrystalline and amorphous materials. Nonetheless, fundamental issues such as lithium potential variations have not been pertinently addressed. Using LiFePO4 as a model system, we inspect such lithium potential variation... | 25,133,677 | [
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Activated CD8+ T lymphocytes inhibit neural stem/progenitor cell proliferation: role of interferon-gamma. | The ability of neural stem/progenitor cells (NSCs) to self-renew, migrate to damaged sites, and differentiate into neurons has renewed interest in using them in therapies for neurodegenerative disorders. Neurological diseases, including viral infections of the brain, are often accompanied by chronic inflammation, whose... | 25,133,679 | [
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Diabetes mellitus aggravates hemorrhagic transformation after ischemic stroke via mitochondrial defects leading to endothelial apoptosis. | Diabetes is a crucial risk factor for stroke and is associated with increased frequency and poor prognosis. Although endothelial dysfunction is a known contributor of stroke, the underlying mechanisms have not been elucidated. The aim of this study was to elucidate the mechanism by which chronic hyperglycemia may contr... | 25,133,692 | [
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Dopamine D2-like receptors modulate unconditioned fear: role of the inferior colliculus. | A reduction of dopamine release or D2 receptor blockade in the terminal fields of the mesolimbic system clearly reduces conditioned fear. Injections of haloperidol, a preferential D2 receptor antagonist, into the inferior colliculus (IC) enhance the processing of unconditioned aversive information. However, a clear cha... | 25,133,693 | [
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Complete mitochondrial genome sequence of the longsnout seahorse Hippocampus reidi (Ginsburg, 1933; Gasterosteiformes: Syngnathidae). | The complete mitochondrial genome sequence of the longsnout seahorse Hippocampus reidi was fisrt determined in this article. The total length of H. reidi mitogenome is 16,529 bp and consists of 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes and 1 control region. The gene order and composition of H. reidi were sim... | 25,133,695 | [
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The complete mitochondrial genome of the hybrid of Siniperca chuatsi (♀) × Siniperca kneri (♂). | In this study, we reported the complete mitochondrial DNA sequence of the hybrid of Siniperca chuatsi (♀)×Siniperca kneri (♂). The total length of the mitochondrial genome is 16,493 bp, with the base composition of 28.61% A, 29.21% C, 16.21% G, and 25.97% T. It contains 2 rRNA genes, 13 protein-coding genes, 22 tRNA ge... | 25,133,697 | [
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The complete mitogenome of Gnathopogon polytaenia (Cypriniformes; Cyprinidae). | The complete mitochondrial genome was sequenced from one of the endemic freshewater gudgeons (Gnathopogon polytaenia) in China. The mitochondrial genome sequence was 16,594 bp in size, and the gene order and contents were identical with the congeneric species G. strigatus and G. elongatus. Six genes (COII, ATP6, COIII,... | 25,133,698 | [
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Subchronic treatment of donepezil rescues impaired social, hyperactive, and stereotypic behavior in valproic acid-induced animal model of autism. | Autism spectrum disorder (ASD) is a group of pervasive developmental disorders with core symptoms such as sociability deficit, language impairment, and repetitive/restricted behaviors. Although worldwide prevalence of ASD has been increased continuously, therapeutic agents to ameliorate the core symptoms especially soc... | 25,133,713 | [
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The involuntary excluder effect: those included by an excluder are seen as exclusive themselves. | People are highly vigilant for and alarmed by social exclusion. Previous research has focused largely on the emotional and motivational consequences of being unambiguously excluded by others. The present research instead examines how people make sense of a more ambiguous dynamic, 1-person exclusion--situations in which... | 25,133,726 | [
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Prediction of chemical biodegradability using support vector classifier optimized with differential evolution. | Reliable computer models for the prediction of chemical biodegradability from molecular descriptors and fingerprints are very important for making health and environmental decisions. Coupling of the differential evolution (DE) algorithm with the support vector classifier (SVC) in order to optimize the main parameters o... | 25,133,742 | [
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A highly selective sulfinate ester probe for thiol bioimaging. | We describe here hitherto unexplored chemistry of the sulfinate ester functional group as being highly selective towards nucleophilic substitution by thiols at physiological pH. Using this cleavable trigger, an optical thiol probe that is suitable for thiol bioimaging has been developed. | 25,133,745 | [
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What you see is not what you get in the PDF document format. | The sharing and storage of scientific knowledge, information and data are today mainly in digitized form, which will become the predominant means of communicating scientific work in the future. One of the best-established formats is the open standard of PDF (Portable Document Format), which is renowned for its flexibil... | 25,133,767 | [
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Electronic patient records in action: Transforming information into professionally relevant knowledge. | The implementation of generic models for organizing information in complex institutions like those in healthcare creates a gap between standardization and the need for locally relevant knowledge. The present study addresses how this gap can be bridged by focusing on the practical work of healthcare staff in transformin... | 25,133,770 | [
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Rearing in seawater mesocosms improves the spawning performance of growth hormone transgenic and wild-type coho salmon. | Growth hormone (GH) transgenes can significantly accelerate growth rates in fish and cause associated alterations to their physiology and behaviour. Concern exists regarding potential environmental risks of GH transgenic fish, should they enter natural ecosystems. In particular, whether they can reproduce and generate ... | 25,133,780 | [
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A long-term macroecological analysis of the recovery of a waterbird metacommunity after site protection. | We used the so called "land-bridge island" or "nested-subsets" theory to test the resilience of a highly fragmented and perturbated waterbird metacommunity, after legal protection of 18 wetlands in the western Mediterranean. Sites were monitored during 28 years and two seasons per year. The metacommunity was composed b... | 25,133,798 | [
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Walking Workstation Use Reduces Ambulatory Blood Pressure in Adults With Prehypertension. | The acute effect of low-intensity walking on blood pressure (BP) is unclear. To determine if the acute use of a walking workstation reduces ambulatory blood pressure (ABP) in prehypertensive men and women. Ten prehypertensive adults participated in a randomized, cross-over study that included a control workday and a wa... | 25,133,860 | [
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Impaired cerebrovascular reactivity in multiple sclerosis. | Cerebrovascular reactivity (CVR) is an inherent indicator of the dilatory capacity of cerebral arterioles for a vasomotor stimulus for maintaining a spontaneous and instant increase of cerebral blood flow (CBF) in response to neural activation. The integrity of this mechanism is essential to preserving healthy neurovas... | 25,133,874 | [
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Metazoan symbionts of the yellow clam, Mesodesma donacium (Bivalvia), in southern Chile: geographical variations. | Mesodesma donacium is a dominant species on sandy beaches along the Chilean coast. However, the only previous parasite records for this species were obtained for the northern Chilean coast (20° S-33° S), which dealt with cestodes, polychaetes, and copepods. In this study, the symbiotic fauna of M. donacium in its south... | 25,133,890 | [
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Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia. | Haploidentical hematopoietic SCT (haplo-HSCT) is to be established in patients with acquired severe aplastic anemia (SAA) refractory to immunosuppressive therapy and lacking HLA-matched related or unrelated donors. Graft failure (GF) and GVHD have been major obstacles to HSCT. A total of 17 children and adolescents wit... | 25,133,891 | [
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A false dichotomy? Mental illness and lone-actor terrorism. | We test whether significant differences in mental illness exist in a matched sample of lone- and group-based terrorists. We then test whether there are distinct behavioral differences between lone-actor terrorists with and without mental illness. We then stratify our sample across a range of diagnoses and again test wh... | 25,133,916 | [
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A pilot study of manual chronic partial exchange transfusion in children with sickle disease. | Objective Red cell exchange transfusion is frequently used in the management of patients with sickle cell disease (SCD) either electively or chronically to maintain hemoglobin S (HbS) <30%. The purpose of this retrospective study was to evaluate the results of manual chronic partial exchange transfusion (MCPET) on l... | 25,133,935 | [
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0.5304041,
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0.01038784,
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-0.2674943,
0.310434,
0.0008034837,
-0.0691639,
0.1631606,
-0.1117519,
0.1229936,
-0.225594... |
A bird's eye view of anisatin induced convulsive seizures in brain by a (1)H NMR based metabolic approach. | Anisatin is the main convulsant component in plants of the genus Illicium, many of which are important spices or folk medicines. The neurotoxicity of anisatin has been widely investigated, mainly focusing on its action on the γ-amino butyrate (GABA) system; however, little is known about the metabolic alterations that ... | 25,133,938 | [
-0.3292426,
0.1155063,
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0.3055236,
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0.07625751,
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0.2935207,
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0.1981045,
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... |
Probing local strain at MX(2)-metal boundaries with surface plasmon-enhanced Raman scattering. | Interactions between metal and atomically thin two-dimensional (2D) materials can exhibit interesting physical behaviors that are of both fundamental interests and technological importance. In addition to forming a metal–semiconductor Schottky junction that is critical for electrical transport, metal deposited on 2D la... | 25,133,959 | [
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0.231774,
-0.2381013,
-0.2663... |
Exome sequencing in the clinical diagnosis of sporadic or familial cerebellar ataxia. | Cerebellar ataxias are a diverse collection of neurologic disorders with causes ranging from common acquired etiologies to rare genetic conditions. Numerous genetic disorders have been associated with chronic progressive ataxia and this consequently presents a diagnostic challenge for the clinician regarding how to app... | 25,133,958 | [
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0.1233503,
... |
Acute postoperative pain relief with immediate-release tapentadol: randomized, double-blind, placebo-controlled study conducted in South Korea. | To broaden the ethnic groups in which tapentadol IR is evaluated for treating acute postoperative pain to include Asians. In this phase 3, multicenter, double-blind, randomized study, 352 Korean adults with moderate-to-severe pain following hallux valgus surgery received tapentadol IR 50 or 75 mg or placebo orally ever... | 25,133,962 | [
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Spectacle correction versus no spectacles for prevention of strabismus in hyperopic children. | Hyperopia (far-sightedness) in infancy requires accommodative effort to bring images into focus. Prolonged accommodative effort has been associated with an increased risk of strabismus (eye misalignment). Strabismus makes it difficult for the eyes to work together and may result in symptoms of asthenopia (eye strain) a... | 25,133,974 | [
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... |
Elucidating the ring inversion mechanism(s) for biscalixarenes. | Biscalix[4]arene can be constructed from a calix[4]arene by substitution of a methylene bridge hydrogen by another equivalent moiety. The use of biscalix[4]arenes (biscal) as precursors for the creation of new polymetallic clusters such as single-molecule magnets has potential in the fields of data storage and other ap... | 25,133,976 | [
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0.08202043,
0.02011643,
0.08097748,
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Single water entropy: hydrophobic crossover and application to drug binding. | Entropy of water plays an important role in both chemical and biological processes e.g. hydrophobic effect, molecular recognition etc. Here we use a new approach to calculate translational and rotational entropy of the individual water molecules around different hydrophobic and charged solutes. We show that for small h... | 25,133,988 | [
-0.219921,
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0.2532641,
0.1116128,
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From micelles to fibers: balancing self-assembling and random coiling domains in pH-responsive silk-collagen-like protein-based polymers. | We study the self-assembly of genetically engineered protein-based triblock copolymers consisting of a central pH-responsive silk-like middle block (S(H)n, where S(H) is a silk-like octapeptide, (GA)3GH and n is the number of repeats) flanked by hydrophilic random coil outer blocks (C2). Our previous work has already s... | 25,133,990 | [
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0.1681708,
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0.1060851,
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0.09373529,
0.2885917,
0.4649171,
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... |
Engineered M13 bacteriophage nanocarriers for intracellular delivery of exogenous proteins to human prostate cancer cells. | The size, well-defined structure, and relatively high folding energies of most proteins allow them to recognize disease-relevant receptors that present a challenge to small molecule reagents. While multiple challenges must be overcome in order to fully exploit the use of protein reagents in basic research and medicine,... | 25,134,017 | [
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0.1865817,
0.0669333,
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Self-assembly of a Ag nanoparticle-modified and graphene-wrapped TiO2 nanobelt ternary heterostructure: surface charge tuning toward efficient photocatalysis. | In recent years, tremendous research efforts have been made towards developing graphene (GR)-based nanocomposites for photocatalytic applications. In this work, surface-coarsened TiO2 nanobelts (SC-TNBs) closely enwrapped with monodispersed Ag nanoparticles (NPs) and GR nanosheets (i.e. Ag/GR/SC-TNBs) were fabricated u... | 25,134,018 | [
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0.2220284,
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Alcohol-related cues potentiate alcohol impairment of behavioral control in drinkers. | The acute impairing effects of alcohol on inhibitory control are well-established, and these disinhibiting effects are thought to play a role in its abuse potential. Alcohol impairment of inhibitory control is typically assessed in the context of arbitrary cues, yet drinking environments are comprised of an array of al... | 25,134,023 | [
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0.1447195,
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0.1560166,
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0.1731635,
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Using ecological measures of smoking trigger exposure to predict smoking cessation milestones. | This study used ecological momentary assessment data from adult daily smokers attempting to quit smoking to assess relations between exposure to contextual risk factors and cessation failure, latency to a first smoking lapse, or progression from lapse to relapse (smoking 7 days in a row). Participants were adult, daily... | 25,134,024 | [
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0.2782656,
0.05052651,
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0.5412977,
0.09601112,
... |
Gambling disorder: estimated prevalence rates and risk factors in Macao. | An excessive, problematic gambling pattern has been regarded as a mental disorder in the Diagnostic and Statistical Manual for Mental Disorders (DSM) for more than 3 decades (American Psychiatric Association [APA], 1980). In this study, its latest prevalence in Macao (one of very few cities with legalized gambling in C... | 25,134,026 | [
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0.2434067,
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0.02911889,
0.3532646,
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0... |
A longitudinal analysis of drinking and victimization in college women: is there a reciprocal relationship? | The purpose of the current study was to assess the relationship between drinking and severe physical and sexual victimization in a sample of 989 college women over 5 years. Participants completed a Web-based survey each fall semester, beginning as first-time incoming freshman, and continuing each year for 5 years. The ... | 25,134,028 | [
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0.3259463,
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0.2897383,
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... |
Employment-based reinforcement of adherence to oral naltrexone in unemployed injection drug users: 12-month outcomes. | Oral naltrexone could be a promising relapse-prevention pharmacotherapy for recently detoxified opioid-dependent patients; however, interventions are often needed to promote adherence with this treatment approach. We recently conducted a study to evaluate a 26-week employment-based reinforcement intervention of oral na... | 25,134,047 | [
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0.1434122,
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... |
The role of avoidance and inflexibility in characterizing response to contingency management for cocaine use disorders: A secondary profile analysis. | Contingency management (CM) is a reinforcement-based approach that provides tangible rewards for objectively verified drug abstinence. CM is the most effective available behavioral intervention for cocaine use disorders; however, response to CM is variable, with significant rates of nonresponse. In the present investig... | 25,134,057 | [
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Composite photothermal platform of polypyrrole-enveloped Fe₃O₄ nanoparticle self-assembled superstructures. | Photothermal nanoplatforms with small size, low cost, multifunctionality, good biocompatibility and in particular biodegradability are greatly desired in the exploration of novel diagnostic and therapeutic methodologies. Despite Fe3O4 nanoparticles (NPs) have been approved as safe clinical agents, the low molar extinct... | 25,134,068 | [
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0.3350945,
0.1868734,
0.3290467,
-0.05562009... |
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