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(2-Nitroethyl)benzene: a major flower scent from the Japanese loquat Eriobotrya japonica [Rosales: Rosaceae].
(2-Nitroethyl)benzene was identified as a major component of the flower scent of the Japanese loquat Eriobotrya japonica [Rosales: Rosaceae], together with p-methoxybenzaldehyde and methyl p-methoxybenzoate. The corresponding volatiles from chopped leaves did not contain these three compounds. This is the first time th...
25,130,732
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Bisphenol A exerts estrogenic effects by modulating CDK1/2 and p38 MAP kinase activity.
Bisphenol A (BPA) is considered to be an endocrine disruptor, but the mechanisms by which it disrupts endocrine functions are poorly understood. Here, we have shown that BPA binds both estrogen receptor (ER)-α and ER-beta (ER-β) using a fluorescence polarization competitive binding assay. In addition, we found that BPA...
25,130,739
[ -0.06455901, -0.2186847, -0.01305403, 0.04678987, -0.0377279, 0.1500373, 0.1017819, 0.1809932, -0.2129976, 0.07207713, -0.1638473, 0.5405484, -0.3449863, 0.2038987, -0.1797551, -0.03498438, -0.4124794, 0.3153258, 0.03427798, -0.3484306, 0.04588688, 0.07684556, 0.06060267,...
Ethanol stress impairs protein folding in the endoplasmic reticulum and activates Ire1 in Saccharomyces cerevisiae.
Impaired protein folding in the endoplasmic reticulum (ER) evokes the unfolded protein response (UPR), which is triggered in budding yeast, Saccharomyces cerevisiae, by the ER-located transmembrane protein Ire1. Here, we report that ethanol stress damages protein folding in the ER, causing activation of Ire1 in yeast c...
25,130,742
[ -0.0003852426, -0.3242237, -0.1097706, 0.04386864, 0.09161656, -0.01293253, -0.02602919, -0.008663735, 0.232118, 0.1846251, 0.1116801, -0.2986633, -0.2000252, 0.03140075, -0.08711459, 0.2113443, -0.3033788, 0.2705901, -0.1444276, -0.2741762, 0.2910309, 0.205714, 0.0306978...
Sleep duration, sleep quality, and obesity risk among older adults from six middle-income countries: findings from the study on global AGEing and adult health (SAGE).
Changes in sleep patterns often occur in older adults. Previous studies have documented associations between sleep duration, sleep quality, and obesity risk in older individuals, yet few studies have examined these trends in lower-income countries. The present cross-sectional study uses nationally representative datase...
25,130,760
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6-Bromoindirubin-3'oxime (BIO) decreases proliferation and migration of canine melanoma cell lines.
Despite recent therapeutic advances, malignant melanoma is an aggressive tumor in dogs and is associated with a poor outcome. Novel, targeted agents are necessary to improve survival. In this study, 6-bromoindirubin-3'-oxime (BIO), a serine/threonine kinase inhibitor with reported specificity for glycogen synthase kina...
25,130,776
[ -0.2948652, 0.1196534, -0.1965373, -0.6937919, -0.1749863, 0.02823883, 0.03722121, 0.111628, 0.1605842, -0.3226649, -0.217875, 0.5548053, -0.09683146, -0.06559559, -0.5277463, -0.1080497, 0.00432996, 0.3432999, -0.01370252, 0.2152734, 0.3354711, 0.4236885, 0.05776976, 0...
An exploratory study of evoked facial affect in adolescent females with anorexia nervosa.
The aim of this exploratory study was to investigate facial affect in adolescent females with anorexia nervosa (AN). Evoked facial affect was recorded whilst AN and control participants (n=34) viewed emotional films. Significantly less facial affect was found in AN adolescents, despite reporting no differences in subje...
25,130,780
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Functional dyspepsia: outcome of focus groups for the development of a questionnaire for symptom assessment in patients suffering from postprandial distress syndrome (PDS).
To date, no patient reported outcomes (PRO) instrument is available for evaluation of treatment efficacy in functional dyspepsia (FD)/postprandial distress syndrome (PDS). The aim of our study was to perform focus group interviews for the development of a new questionnaire for assessing symptom pattern and severity in ...
25,130,784
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Footprints of cardiac mechanical activity as expressed in lung Doppler signals.
To determine the diagnostic information contained in cardiac pulsatile pressure waves as expressed in the Doppler signals recorded over the right lung. The pulsatile characteristics of the pulmonary vascular system were studied by means of the novel pulse Doppler technology in 38 control volunteers, 31 patients with at...
25,130,794
[ -0.1459375, 0.2820057, -0.313615, -0.1093135, 0.1929118, -0.3025146, -0.2087436, -0.05021369, 0.1334243, 0.0793963, -0.08811833, 0.1380439, -0.0756668, -0.2698524, 0.1049968, -0.09788648, 0.04985352, 0.0685571, 0.01497122, -0.1956977, 0.379526, -0.12373, -0.4633811, 0.3...
[Anti-leukemia mechanism of miR-17 and miR-20a silencing mediated by miRNA sponge].
This study was aimed to quantitatively detect the expression levels of pre-miR-17 and pre-miR-20a in acute leukemia patients and eight kinds of leukemia cell lines, and to investigate the anti-leukemia mechanism of miR-17 and miR-20a silence mediated by miRNA Sponge. Quantitative real-time PCR was used to detect the mR...
25,130,806
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[Association of XRCC1 genetic polymorphism with susceptibility to non-Hodgkin's lymphoma].
The purpose of this study was to explore the association between X-ray repair cross-complementing group 1 (XRCC1)gene polymorphism and non-Hodgkin's lymphoma risk. A total of 282 non-Hodgkin's lymphoma (NHL) patients and 231 normal controls were used to investigate the effect of three XRCC1 gene polymorphisms (rs25487,...
25,130,814
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[Comparative analysis of collecting mononuclear cells from peripheral blood by using Fenwal CS-3000 plus, haemonetics MCS plus and COBE spectra separators].
This study was aimed to compare the collection efficiency of mononuclear cells (MNC) from peripheral blood as well as the changes of blood-related indices in patient by using 3 cell separators. MNC were collected from 94 tumor patients by using Fenwal CS-3000plus, Haemonetics MCSplus and COBE spectra separators. Routin...
25,130,837
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[Research advances on roles of ADAMTS-13 in thrombotic diseases].
ADAMTS-13 is a plasma metalloprotease that cleaves von willebrand factor (vWF).At the present,it has been made great progresses on its structure, biological characteristics and function. ADAMTS-13 plays an important role in artery and venous thrombosis,besides controlling the cleaving of vWF, and the activity of the AD...
25,130,850
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Retinoic acid signaling in cancer: The parable of acute promyelocytic leukemia.
Inevitably fatal some 40 years, acute promyelocytic leukemia (APL) can now be cured in more than 95% of cases. This clinical success story is tightly linked to tremendous progress in our understanding of retinoic acid (RA) signaling. The discovery of retinoic acid receptor alpha (RARA) was followed by the cloning of th...
25,130,873
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The promise of telemedicine.
We have developed an extraordinary capability to capture and transmit digital ocular imaging, enabling remote interpretation of every aspect of the eye. The issues regarding telemedicine were primarily technical and procedural when this journal first reviewed the topic in 1999. Fourteen years later, telemedicine presen...
25,130,894
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The cultural dimension of tightness-looseness: An analysis of situational constraint in Estonia and Greece.
The importance of tightness-looseness as a dimension that explains a considerable amount of variance between cultures was demonstrated by Gelfand et al. (2011). Tight nations have many strong norms and a low tolerance of deviant behaviour, whereas loose nations have weak social norms and a high tolerance of deviant beh...
25,130,924
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Individual factors enhance poor health-related quality of life outcome in multiple sclerosis patients. Significance of predictive determinants.
Individual factors in multiple sclerosis (MS) patients may modify the reliability of health-related quality of life (HRQOL) assessment. Knowledge of these effects may enable physicians to identify patients at risk for poor perceived health. To investigate what individual factors may interact with MS symptoms and their ...
25,130,927
[ 0.06743814, 0.04825548, 0.1078472, 0.1086817, 0.02973204, -0.6846534, 0.07275105, 0.1957481, -0.3131146, -0.4395112, -0.06267089, -0.05892599, -0.02501003, -0.1529561, -0.1876225, -0.02650414, -0.3333963, 0.06440894, -0.09543542, 0.09760205, -0.1164608, 0.5565315, 0.08895...
Increased proinflammatory cytokines in sera of patients with multifocal motor neuropathy.
Multifocal motor neuropathy (MMN) is characterized by clinical improvement with intravenous immunoglobulin and the frequent detection of anti-ganglioside antibodies. However, the immunological background of the neuronal damage in MMN is still unclear. The aim of this study is to investigate abnormalities in the cytokin...
25,130,929
[ 0.07740748, -0.009166717, 0.0888945, -0.2684059, -0.003630957, -0.07481437, -0.3500085, -0.1003085, -0.536335, -0.05697282, 0.1196888, 0.05890901, 0.002122992, 0.3786295, 0.1316209, -0.1371289, -0.1484001, -0.02675664, -0.04477594, -0.03967072, 0.07459383, 0.2949598, -0.0...
Plantar pressure characteristics in hallux valgus feet.
Due to the pathoanatomical changes in hallux valgus feet, the plantar flexion moment of the first metatarsophalangeal joint is reduced. Therefore, load bearing of the hallux is decreased during push-off. We assessed loading parameters in hallux valgus feet. Based on dorsal-plantar weight bearing radiographs of 61 feet,...
25,130,961
[ -0.2481838, 0.09656832, 0.08927044, 0.01126314, 0.04299932, -0.3385799, -0.3595095, -0.06661392, -0.2320953, 0.04065746, -0.01938704, -0.4943362, 0.02239909, -0.5166966, 0.08749127, 0.07054273, 0.2664024, 0.3919332, -0.5228096, 0.2002685, 0.08788119, -0.03221461, -0.09985...
Surgical management of thymic epithelial tumors in children: lessons from the French Society of Pediatric Oncology and review of the literature.
We report the results of a French multicenter retrospective study based on a period of more than 30 years and a review of the literature in order to more clearly define the surgical approach and specific pediatric risk factors. Clinical data of children comprising all histologic subtypes of thymic epithelial tumors (TE...
25,130,986
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How accurate is sperm morphology as an indicator of sperm function?
Sperm morphology has been consistently correlated with fertilisation success or failure. The clinical relevance of the percentage normal spermatozoa has been a widely discussed topic amongst infertility specialists and scientists. This study aimed to evaluate the role of sperm morphology as an indicator of additional s...
25,130,990
[ 0.3663455, 0.1602821, 0.4809228, 0.1290099, 0.2073408, -0.0599285, -0.1937975, 0.4251991, 0.2381024, -0.3427528, 0.1428953, 0.2494773, -0.119834, 0.2835295, -0.2068452, -0.1658344, -0.3920669, 0.3173088, -0.3634095, -0.4634749, 0.35721, 0.09499032, -0.1112649, -0.082950...
Waiting for a kidney transplant: association with anxiety and stress.
The pretransplantation period is characterized by many stressful events that can result in symptoms of anxiety and stress and ultimately can have a negative impact on graft outcome. Our objective was to evaluate the association between symptoms of anxiety and stress in patients awaiting kidney transplantation. This was...
25,131,015
[ -0.004864005, -0.238216, 0.1864614, 0.2532674, 0.02247768, -0.3530199, 0.02730437, -0.1768735, -0.2297917, -0.1277349, 0.05209764, 0.2178934, -0.3128705, -0.1311508, -0.2108699, -0.2644454, -0.04469885, 0.08301579, -0.1064348, 0.3279279, -0.1013241, 0.1899465, -0.09070808...
Grade IV fibrosis interferes in biliary drainage after Kasai procedure.
Biliary atresia (BA) is the most common cause of liver transplantation in children. The earlier the treatment is done, the better the prognosis. The aim is to evaluate the impact of late diagnosis in children with BA, including the histopathological findings and success rate of biliary drainage in patients submitted to...
25,131,036
[ -0.002992037, -0.3256907, 0.2329281, 0.08369055, -0.2849374, -0.5373346, 0.1904172, -0.1281887, -0.2476913, 0.1606637, 0.1243926, 0.1284624, -0.3168663, -0.5103921, -0.6575819, -0.6814909, 0.4872836, 0.04818925, 0.02643774, -0.364778, -0.03735735, 0.04983705, -0.07288536,...
Surface electromyography for respiratory assessment of liver transplant candidates, healthy subjects and after chevron post-operative incision.
Surface electromyography is a noninvasive technique for detecting the activity of skeletal muscles and especially the muscles for respiratory compliance; namely, the diaphragm and rectus abdominis. This study compares these muscles in healthy individuals, liver disease patients, and after abdominal surgery. To study mu...
25,131,032
[ 0.02289515, -0.425619, -0.09216761, -0.3713253, -0.06563588, -0.181701, -0.1734163, -0.4004655, 0.05748295, -0.04009316, 0.2602189, -0.6053699, 0.1168496, 0.03451534, -0.4427883, 0.02896954, -0.7586521, 0.09765059, -0.2562032, -0.2874575, -0.2813165, -0.2413928, 0.2301278...
Portal versus systemic venous drainage of the pancreatic graft: the effect on glucose metabolism in pancreas and kidney transplant recipients.
Two different methods of graft venous drainage are used in pancreas transplantation: portal (PVD) and systemic (SVD). PVD is considered to be more physiologic due to its similarity to venous outflow of the native pancreas. The aim of our study was to compare glucose metabolism in Type 1 diabetic recipients of kidney an...
25,131,068
[ -0.07180513, -0.3161261, -0.7616898, -0.133675, 0.2262488, -0.7555896, -0.1471264, 0.4215938, -0.1838997, 0.08171894, 0.3054456, -0.07421926, -0.4271429, 0.005951338, -0.1122734, -0.5246132, -0.1798331, 0.1991123, 0.07558051, 0.002808359, -0.03835644, 0.4983417, 0.1069614...
A novel screening test for detecting graft thrombosis after pancreatic transplantation using contrast-enhanced ultrasonography with sonazoid.
Pancreatic graft thrombosis is the primary cause of nonimmunologic graft loss, with an incidence ranging from 5% to 15%. Therefore, developing a screening test to detect graft thrombosis after pancreatic transplantation is important. We created a screening test to assess graft thrombosis after pancreatic transplantatio...
25,131,070
[ 0.1360168, 0.03230556, -0.007657885, -0.2154507, 0.1900991, -0.02040892, 0.2302355, 0.05477508, -0.2027028, -0.08999605, 0.02592359, -0.02218855, -0.1826894, 0.01482812, -0.02105795, -0.1320884, -0.2588965, 0.2101368, -0.006888049, -0.296981, 0.1125017, 0.2982261, 0.07869...
Islet oxygen consumption rate dose predicts insulin independence for first clinical islet allotransplants.
Human islet allotransplantation for the treatment of type 1 diabetes is in phase III clinical trials in the U.S. and is the standard of care in several other countries. Current islet product release criteria include viability based on cell membrane integrity stains, glucose-stimulated insulin release, and islet equival...
25,131,089
[ -0.02987087, -0.1603429, -0.09456617, -0.1530373, -0.1046118, -0.2337354, 0.1723524, 0.4643365, 0.4740833, -0.0284727, 0.1483799, -0.2727088, -0.1197489, 0.1318949, -0.1811893, -0.2958748, -0.05813487, 0.08105961, 0.0614688, 0.01226022, 0.06822219, 0.1919722, 0.03242655, ...
Human islet viability and function is maintained during high-density shipment in silicone rubber membrane vessels.
The shipment of human islets (IE) from processing centers to distant laboratories is beneficial for both research and clinical applications. The maintenance of islet viability and function in transit is critically important. Gas-permeable silicone rubber membrane (SRM) vessels reduce the risk of hypoxia-induced death o...
25,131,090
[ -0.223061, -0.2085594, 0.04565088, -0.006242555, -0.002812656, -0.005012, 0.2871334, 0.2956538, 0.4702015, 0.1124639, -0.03575384, 0.05961966, -0.03501928, -0.01985045, -0.1849396, -0.151412, -0.2316151, -0.1849953, -0.07013334, 0.1459379, 0.0744005, 0.08520508, 0.1701495...
Xenograft of microencapsulated Sertoli cells for the cell therapy of type 2 diabetes mellitus in spontaneously diabetic nonhuman primates: preliminary data.
Insulin resistance in type 2 diabetes mellitus (T2DM) may be due to a chronic inflammation of the visceral adipose tissue (VAT) leading to local and systemic increases in proinflammatory cytokines. Microencapsulated porcine Sertoli cells (MC-pSC), by provision of immunomodulatory and trophic factors, have been successf...
25,131,093
[ 0.1984809, -0.3090135, -0.2755534, -0.3159296, -0.1067981, -0.436592, 0.02796029, 0.2619192, 0.06202259, 0.08210244, 0.04117412, 0.08052256, -0.2913107, -0.2111773, -0.5077363, -0.2446543, -0.01495016, 0.1279285, 0.01304177, 0.4208114, -0.03651671, 0.2519792, 0.007627126,...
Donor organ shortage crisis: a case study review of a financial incentive-based system.
Current organ supply system depends on altruistic noncoercive donation, which has failed to meet the demand of organ transplantation. Providing financial incentives to donors is one of several approaches to address organ shortage. However, its feasibility is debatable as it relates to medical, ethical, and economic dim...
25,131,100
[ -0.3214502, -0.2587812, -0.2100438, -0.02133068, 0.378529, -0.3340029, -0.2471484, 0.1991227, -0.04075677, 0.1668774, 0.002069677, -0.05127325, -0.2271284, 0.3117551, -0.3556233, 0.1105223, -0.1816015, -0.004477683, -0.1173614, -0.1543464, -0.1250178, -0.2292168, 0.149845...
Successful management of a ruptured mycotic pseudoaneurysm following pancreas transplantation using bovine pericardial patch: a case report.
Arterial mycotic pseudoaneurysms are a rare complication of pancreas transplantation. Rupture results in catastrophic hemorrhage with a high risk of mortality. Definitive management is complicated by an extensive arterial defect within a contaminated surgical field. Synthetic vascular grafts often fail due to subsequen...
25,131,098
[ -0.10848, 0.07060178, -0.5160804, 0.1305328, -0.2006039, -0.3459869, -0.1299646, -0.06649105, 0.236955, -0.05964442, 0.163388, -0.2457934, -0.1532664, -0.1583602, -0.1654276, 0.03501777, -0.4026057, -0.1123712, 0.1613958, -0.2238702, 0.004100422, 0.3289848, 0.09069558, ...
Histologic evaluation of organ preservation injury and correlation with cold ischemia time in 13 intestinal grafts.
Lesions produced in the graft mucosa due to harvesting, storage, and implantation must be graduated to assess the subsequent protocolized biopsy specimens. The aim is to identify type and intensity of graft mucosal lesions observed immediately after implantation. Congestion, hemorrhage, microthrombi, neutrophilic infil...
25,131,115
[ -0.2087411, 0.07312784, 0.5315312, 0.01190529, 0.1008536, -0.4087816, 0.04037798, 0.0760171, 0.03000465, -0.06798798, 0.1856269, 0.0341444, -0.5036147, 0.1080231, -0.7418879, -0.346773, 0.1940617, -0.3011126, 0.04116886, 0.4226789, -0.02055957, 0.324382, 0.002176793, -0...
Impact of intestinal transplantation for intestinal failure in Japan.
The prognosis of intestinal failure has improved dramatically in the past few decades with the development of parenteral nutrition (PN). However, PN-dependent patients still have numerous complications. Intestinal transplantation can significantly improve their prognosis and quality of life. We report on the impact of ...
25,131,121
[ 0.08193881, -0.5074656, 0.1686052, -0.3969218, 0.2024902, 0.2037842, 0.2953786, 0.2136437, -0.01785061, -0.2783318, 0.227726, -0.374459, -0.3054655, 0.119835, -0.2037628, -0.3329743, -0.01394763, 0.3345499, -0.02418498, 0.0943955, -0.211686, 0.4747309, -0.05424597, -0.1...
Psychiatric disorders in patients undergoing intestinal transplantation.
Psychiatric disorders are common in chronic disease states; intestinal transplantation recipients may therefore be at high risk for psychiatric disorder (PD). We sought to investigate the frequency and type of PD in our cohort of patients undergoing transplantation between 2007 and 2012. The notes of 25 patients who ha...
25,131,124
[ -0.285448, -0.3324149, 0.07581084, 0.01099019, 0.06215753, 0.08348676, -0.1020348, -0.334426, 0.1075602, -0.23355, 0.317841, -0.2103877, -0.08435168, 0.1686166, -0.05325833, -0.04256211, -0.514209, 0.1445411, -0.1336935, 0.3406966, -0.1195717, 0.4534189, -0.3543296, 0.0...
Early histopathological changes in new-onset diabetes after kidney transplantation.
New-onset diabetes after transplantation (NODAT) is one of the most common complications after kidney transplantation. Patients were randomly assigned to receive cyclosporine A-based or tacrolimus-based immunosuppression. Fasting and oral glucose tolerance tests were performed, and the patients were assigned to one of ...
25,131,129
[ 0.3252625, -0.002218541, 0.04544632, 0.04396417, 0.2784085, -0.287253, 0.07779055, 0.4467806, 0.2766393, -0.2497604, 0.08364467, -0.3256945, 0.1123432, 0.1046631, -0.4566857, -0.3189611, 0.007096548, -0.1683559, 0.03354265, -0.0599728, -0.2060088, 0.2503702, -0.3893673, ...
Three-year longitudinal clinical trial of arterial function assessed by a oscillometric non-invasive method in comparison with carotid sclerosis and transferrin kidney-transplanted patients.
Chronic kidney disease remains one of the main risk factors of cardiovascular disease. However, patients with kidney transplantation have better life expectancy and better quality of life compared with patients on dialysis. In patients with a well-functioning graft, the main cause of death is cardiovascular in origin. ...
25,131,132
[ 0.06906854, 0.01584044, -0.0182583, 0.1061057, 0.3342141, -0.5581129, 0.00448608, 0.128306, 0.09953096, -0.2706892, -0.1617422, -0.1354749, 0.1036274, 0.01434555, -0.2955708, -0.1732161, -0.3067037, -0.3065736, -0.4562126, 0.4980494, -0.0003193167, 0.2062178, -0.2999946, ...
Psychogenic nonepileptic seizures: should we use response to AEDS as a red flag for the diagnosis?
Lack of response to anti-epileptic drugs (AEDS) is considered a "red flag" pointing to a diagnosis of Psychogenic Nonepileptic Seizures (PNES). On the other hand, placebo effects are relevant in any medical condition with a complex psychosocial component. We aimed to evaluate the presence and frequency of a placebo res...
25,131,161
[ -0.03580289, 0.224542, -0.1527105, -0.3495224, -0.01572381, -0.2388198, -0.04589574, 0.007204104, -0.04279185, -0.05424093, -0.05337434, 0.5848771, 0.05225837, -0.1240772, -0.3178194, -0.02977302, -0.2505089, 0.3529189, 0.06499004, -0.0279597, -0.1000258, 0.1686603, -0.12...
A new target for the old regulator: H-NS suppress T6SS secretory protein EvpP, the major virulence factor in the fish pathogen Edwardsiella tarda.
The evpP gene in fish pathogen Edwardsiella tarda, coding the T6SS secretory protein EvpP and carrying an evpA-evpO independent promoter region, was crucial for host cell invasion. The transcription of evpP was positively regulated by either the two-component system EsrA-EsrB or iron concentration, and its overexpressi...
25,131,176
[ -0.04073213, 0.05567204, -0.01532827, -0.09783015, -0.3106216, -0.2046994, 0.1515392, 0.07779163, -0.04552998, 0.01700265, 0.06334482, 0.2620776, -0.2151971, -0.2241192, -0.3575687, -0.1783591, -0.03570997, -0.2749572, -0.05590092, -0.01232309, 0.3316746, 0.2598105, -0.34...
Surface confined heteroleptic copper(II)-polypyridyl complexes for photonuclease activity.
Heteroleptic copper(II)-polypyridyl complexes with extended π-conjugated, aromatic terminal units were immobilized on glass/Si substrates to intercalate DNA and cleave it upon photoexposure. Photonuclease activity is shown to be high, well reproducible and non-destructible towards the assembled complexes.
25,131,185
[ -0.2134071, -0.06760054, -0.1203727, -0.08118711, 0.05858491, -0.1958536, -0.4513024, 0.06777148, 0.4318328, 0.2703403, -0.03683736, 0.09072322, 0.1269946, -0.004753599, -0.7628633, 0.08568778, -0.5364127, 0.2869156, -0.1506028, 0.1531242, 0.2842947, 0.2231139, -0.256509,...
No impact of endogenous prothrombotic conditions on the risk of central venous line-related thrombotic events in children: results of the KIDCAT study (KIDs with Catheter Associated Thrombosis).
Central venous lines (CVLs) are the major exogenous risk factor for deep venous thrombosis (DVT) in children. The study objective was to assess whether endogenous prothrombotic conditions contribute to the risk of CVL-related DVT in children. This was a cohort study of consecutive children with heart disease requiring ...
25,131,188
[ 0.288405, 0.0790059, -0.1376604, 0.1720509, 0.1159321, -0.06817431, 0.3760121, 0.06711778, -0.133137, 0.2206524, 0.009098369, 0.5538425, 0.1681008, 0.005636745, 0.04550955, -0.1519764, -0.1425485, 0.05338036, -0.07254577, -0.03460732, 0.4983005, 0.09753677, -0.4144503, ...
Evaluation of 18S rDNA PCR assay using skin fragments as a diagnostic test for Trypanosoma caninum.
Trypanosoma caninum is a new species that has been recently identified in Brazil and infects domestic dogs. To date, no accurate diagnostic assays for this parasite have been established; thus, our aim was to evaluate more than one type of PCR for the diagnosis and molecular screening of T. caninum in 229 dogs living i...
25,131,189
[ -0.005484287, 0.0239393, 0.2322248, -0.1635402, -0.063913, 0.06852796, -0.2657019, -0.02430076, 0.004513941, -0.4352552, 0.01728309, -0.1490555, 0.1152852, -0.1348346, -0.4342354, -0.1536026, -0.2503264, -0.07081629, 0.005543482, -0.1829549, 0.2732871, -7.610497e-8, 0.107...
Gas2l3 is essential for brain morphogenesis and development.
Growth arrest-specific 2-like 3 (Gas2l3) is a newly discovered cell cycle protein and a cytoskeleton orchestrator that binds both actin filament and microtubule networks. Studies of cultured mammalian cells established Gas2l3 as a regulator of the cell division process, in particular cytokinesis and cell abscission. Th...
25,131,197
[ 0.0226802, 0.2374143, 0.02467252, -0.09654644, 0.198624, -0.1225628, -0.207829, 0.002015302, -0.1106191, -0.02617074, -0.1243567, 0.03822915, -0.1951958, -0.007329387, -0.3165206, 0.26231, -0.3625898, 0.1666877, -0.2052902, -0.00373718, 0.3266189, 0.3607592, -0.2009787, ...
Reconstruction of insulin signal flow from phosphoproteome and metabolome data.
Cellular homeostasis is regulated by signals through multiple molecular networks that include protein phosphorylation and metabolites. However, where and when the signal flows through a network and regulates homeostasis has not been explored. We have developed a reconstruction method for the signal flow based on time-c...
25,131,207
[ -0.02655259, -0.286408, -0.218698, 0.02898193, 0.1086627, -0.09772374, 0.09413315, 0.5253339, -0.04668077, -0.05520416, 0.1913691, -0.1742115, -0.2466789, 0.06101926, -0.1776602, -0.03554002, -0.1288681, 0.07879008, -0.03054249, 0.03782044, 0.07535071, 0.1212234, -0.25260...
Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease.
Macrophages can fuse to form osteoclasts in bone or multinucleate giant cells (MGCs) as part of the immune response. We use a systems genetics approach in rat macrophages to unravel their genetic determinants of multinucleation and investigate their role in both bone homeostasis and inflammatory disease. We identify a ...
25,131,209
[ 0.1921762, 0.02038526, -0.04699894, -0.1797287, -0.06096761, -0.1313248, -0.04661813, 0.1203706, -0.06408605, -0.1620395, -0.2070765, 0.02697593, 0.02336418, 0.05893876, -0.4664825, -0.1201737, -0.2826298, -0.06707916, -0.05596287, 0.06398471, -0.08969399, 0.1979973, -0.0...
Relationship between chronic diarrhea with normal colonoscopy findings and terminal ileum lesions.
The causes and mechanisms of chronic diarrhea are complex. This study aimed to explore the relationship between chronic diarrhea with normal colonoscopy findings and terminal ileum lesions. All cases were collected from January 2009 to June 2010. The 40 patients in the patient group had chronic diarrhea with normal col...
25,131,227
[ 0.04663863, -0.1473255, 0.5427579, 0.5742845, 0.09517891, -0.1997789, 0.4998108, 0.2425539, 0.1814202, -0.1270853, -0.1521607, -0.2678616, -0.2146898, 0.4284634, 0.1065841, -0.2729849, -0.4597562, -0.07787091, -0.09744254, 0.08502685, -0.419199, 0.335277, -0.08967321, -...
The small GTPases regulate HMC05-induced NQO-1 expression with an antioxidant effect in smooth muscle cells.
Recently, Banhabackchulchunmatang (HMC05) has been implicated as a preventive and/or therapeutic candidate for cardiovascular diseases due to its inhibition of atherosclerosis lesions and its reduction of neointima formation. Knowledge of the mechanism of HMC05 in smooth muscle cells (SMC) is limited. However, SMC may ...
25,131,260
[ -0.3523842, 0.5373914, -0.2116854, -0.1183365, -0.1292482, -0.214773, 0.03610343, -0.03042353, 0.2209607, -0.1912221, 0.2451023, -0.06342992, -0.129663, 0.05152728, -0.5837448, -0.2352255, -0.3963032, 0.2423873, -0.1095334, -0.04052681, 0.1436071, 0.3219013, 0.241698, -...
Uses of cancer registries for public health and clinical research in Europe: Results of the European Network of Cancer Registries survey among 161 population-based cancer registries during 2010-2012.
To provide insight into cancer registration coverage, data access and use in Europe. This contributes to data and infrastructure harmonisation and will foster a more prominent role of cancer registries (CRs) within public health, clinical policy and cancer research, whether within or outside the European Research Area....
25,131,265
[ 0.0747631, -0.1132461, 0.1122681, -0.3887802, -0.3704509, -0.09127206, 0.05810262, -0.02655117, 0.02158798, 0.1911075, 0.008852724, -0.08013286, -0.2024109, -0.2458444, -0.001481533, -0.2740543, 0.03868407, 0.2349264, 0.04050227, 0.1885878, 0.3639418, 0.256502, -0.2863634...
Third-grade retention and reading achievement in Texas: a nine year panel study.
The academic performance of over 38,000 Texas students who failed the state's 1994 reading test was examined through their sophomore year in high school. Propensity score matching resulted in strata with retained and promoted students of comparable observed characteristics. Reading scores were analyzed using a two-leve...
25,131,271
[ 0.0103635, 0.3387329, 0.06271186, -0.1442171, 0.2721159, -0.1986132, -0.01954436, -0.02946611, 0.09276145, -0.07215969, 0.09709062, 0.3406201, -0.1280939, -0.1668525, -0.5246614, 0.03079272, 0.3318481, -0.1290678, -0.2150606, -0.1145151, 0.1838058, 0.1573614, -0.1194175, ...
Homonegativity among first and second generation migrants in Europe: the interplay of time trends, origin, destination and religion.
Previous studies reported declining disapproval of homosexuality in Europe but have simultaneously identified the decelerating effect of religiosity and the higher disapproval of homosexuality among migrants. In this paper, we address disapproval of homosexuality among first- and second-generation migrants in Europe by...
25,131,278
[ -0.01575056, 0.1381416, -0.1825977, -0.01205435, 0.2810184, -0.3778647, -0.1923431, -0.02974948, 0.06817655, 0.04800769, 0.1110427, -0.1778514, -0.09049001, -0.04242831, -0.1147119, -0.03669761, -0.03513244, 0.01285275, -0.353181, -0.1457963, 0.1926449, 0.3154026, -0.0624...
College quality and hourly wages: evidence from the self-revelation model, sibling models and instrumental variables.
This paper addresses the recent discussion on confounding in the returns to college quality literature using the Norwegian case. The main advantage of studying Norway is the quality of the data. Norwegian administrative data provide information on college applications, family relations and a rich set of control variabl...
25,131,279
[ 0.187956, 0.0004483529, -0.1977975, -0.04461922, 0.2684944, -0.5147823, 0.07265973, -0.1299162, -0.2637422, 0.08412604, -0.1314542, 0.2115845, 0.09681106, -0.02896236, -0.2844381, -0.1877021, 0.1160156, 0.14103, 0.05876925, -0.03647629, 0.1984639, 0.260932, 0.1120612, 0...
Identifying predictors of survey mode preference.
To increase the likelihood of response, many survey organizations attempt to provide sample members with a mode they are thought to prefer. Mode assignment is typically based on conventional wisdom or results from mode choice studies that presented only limited options. In this paper we draw heavily on research and the...
25,131,280
[ -0.2140969, 0.2030481, -0.3736096, -0.1812076, -0.001303018, -0.1080302, -0.4438334, 0.08943552, 0.192573, -0.05975562, 0.01806782, -0.4762964, 0.2529955, 0.2409109, -0.2127141, 0.05459967, -0.4728674, 0.07461371, -0.2156833, -0.02209727, 0.3648838, 0.1066462, 0.08923369,...
When do doctors follow patients' orders? Organizational mechanisms of physician influence.
Physicians, like other professionals, are expected to draw from specialized knowledge while remaining receptive to clients' requests. Using nationally representative U.S. survey data from the Community Tracking Study, this paper examines the degree to which physicians are influenced by patients' requests, and how physi...
25,131,283
[ -0.02235924, 0.01193895, 0.1086341, 0.001108359, 0.4539928, -0.02542109, 0.1671459, 0.2183802, 0.1962966, 0.01734869, -0.1664898, -0.2170646, 0.1517486, 0.004368563, -0.2428396, 0.03784069, -0.2327687, -0.02182912, -0.1448931, 0.06208766, 0.02627924, -0.1553938, -0.081656...
Twelve-year survey (2001-2012) of the antimicrobial susceptibility of Streptococcus pneumoniae isolates from otorhinolaryngology clinics in Miyagi Prefecture, Japan.
Streptococcus pneumoniae is one of the most common bacteria causing otorhinolaryngological infections, such as acute otitis media and upper respiratory tract infection. Our group surveyed the drug susceptibility profile of S. pneumoniae isolates from otorhinolaryngology patients. A total of 41,069 S. pneumoniae isolate...
25,131,291
[ -0.02940036, -0.31909, -0.04458262, -0.2939723, -0.1893389, 0.3013189, -0.3526244, -0.2440219, 0.387093, -0.1715557, 0.2283715, 0.1536425, -0.09544789, 0.3316763, 0.1504531, -0.1611526, 0.04566704, 0.4583988, -0.2837272, 0.378591, 0.2597242, -0.3769637, 0.01115355, -0.1...
Vmp1 regulates PtdIns3P signaling during autophagosome formation in Dictyostelium discoideum.
Generation and turnover of phosphatidylinositol 3-phosphate (PtdIns3P) signaling is essential for autophagosome formation and other membrane traffic processes. In both Dictyostelium discoideum and mammalian cells, autophagosomes are formed from specialized regions of the endoplasmic reticulum (ER), called omegasomes, w...
25,131,297
[ -0.3237506, -0.09638428, -0.2725698, -0.3291087, -0.06382944, -0.2491685, -0.234424, 0.2606465, -0.07749063, 0.3056857, 0.2623081, 0.03763014, -0.4035384, -0.05087644, -0.2076603, -0.07620631, -0.3255219, 0.2839894, 0.3217242, -0.03537584, 0.1788999, 0.5194312, -0.0277854...
Lateral MoS2 p-n junction formed by chemical doping for use in high-performance optoelectronics.
This paper demonstrates a technique to form a lateral homogeneous 2D MoS2 p-n junction by partially stacking 2D h-BN as a mask to p-dope MoS2. The fabricated lateral MoS2 p-n junction with asymmetric electrodes of Pd and Cr/Au displayed a highly efficient photoresponse (maximum external quantum efficiency of ∼7000%, sp...
25,131,298
[ -0.2041736, 0.1159733, 0.03866104, -0.06968492, 0.2989849, 0.0568167, -0.235643, 0.1200581, 0.03461369, 0.133127, -0.1943245, 0.493295, 0.1110223, 0.002070947, -0.4643407, -0.4544123, -0.6432267, 0.05678253, 0.3332089, 0.01971228, 0.1307063, 0.1206853, -0.2117473, -0.02...
Hybrid technique for laparoscopic incisional ventral hernia repair combining laparoscopic primary closure and mesh repair.
Incisional ventral hernia is one of the most common surgical complications after laparotomy. Laparoscopic repair of incisional ventral hernia has been conducted recently, and the advantages of this procedure have been reported. However, in large orifice cases, the recurrence rate is increased. To improve recurrence rat...
25,131,330
[ 0.1983688, 0.09645654, -0.003761441, 0.1551013, 0.1008466, -0.07125308, -0.4238078, -0.0071166, 0.2508971, 0.1188232, 0.2479067, -0.4363593, 0.261776, -0.1834075, -0.5935242, -0.1221555, -0.5476464, -0.01128226, 0.02691351, -0.5004482, 0.2384999, 0.2091651, -0.04398714, ...
IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection.
Interferon-inducible transmembrane proteins 1, 2 and 3 (IFITM1, IFITM2 and IFITM3) have recently been identified as potent antiviral effectors that function to suppress the entry of a broad range of enveloped viruses and modulate cellular tropism independent of viral receptor expression. However, the antiviral effect a...
25,131,332
[ -0.2608275, 0.07101555, -0.1934567, -0.06410485, -0.07566825, -0.1749415, -0.0215188, 0.4813397, 0.2014959, -0.03005096, -0.06309824, -0.1705435, -0.002528066, -0.3241169, -0.257471, -0.0939846, -0.1446308, -0.03833565, 0.05204231, -0.3087984, -0.05776088, 0.226101, -0.21...
Dietary squid ink polysaccharides ameliorated the intestinal microflora dysfunction in mice undergoing chemotherapy.
Gastrointestinal mucositis and infection by chemotherapy treatment are associated with alteration of intestinal microflora and bacterial translocation due to the potential damage induced by anti-cancer drugs on the intestinal barrier and microbiota homeostasis. This study aimed to investigate the protective effect of d...
25,131,333
[ -0.1864735, -0.1669085, 0.1254404, 0.07239833, 0.1812201, -0.05154693, -0.1621266, 0.3823678, 0.3099508, -0.1919576, 0.01373459, -0.1945511, -0.3534966, 0.2853315, -0.6054961, 0.03193431, -0.5190996, -0.0302284, 0.03945637, 0.03370524, 0.2182371, -0.04260684, 0.003645749,...
Control of neural circuit formation by leucine-rich repeat proteins.
The function of neural circuits depends on the precise connectivity between populations of neurons. Increasing evidence indicates that disruptions in excitatory or inhibitory synapse formation or function lead to excitation/inhibition (E/I) imbalances and contribute to neurodevelopmental and psychiatric disorders. Leuc...
25,131,359
[ 0.1091561, -0.1465076, 0.06971119, -0.3378932, 0.02601633, -0.2251427, -0.1525073, 0.003140397, 0.06558776, 0.4490873, -0.002221665, 0.314976, -0.06208413, 0.05160825, -0.3429258, -0.07877269, -0.5525271, 0.1335955, -0.004048057, -0.0309092, 0.06009402, 0.2337151, 0.06795...
[Place and role of the pleura in non-small cell lung cancer dissemination].
The pleural involvement (PLI) in non-small cell lung cancer (NSCLC) has a poor prognosis, even though it might be very heterogeneous. A multicentric retrospective descriptive study was performed over 2329 patients who were operated for NSCLC between 1979 and 2010. The patients with PLI were classified in P(Parietal)PLI...
25,131,365
[ 0.08579732, -0.3406211, 0.09751581, -0.6710756, -0.2671283, -0.2789445, -0.0661878, -0.1306576, -0.2636766, 0.2244974, 0.1408689, 0.1599061, -0.1946987, -0.4640586, -0.3656361, -0.4051968, 0.1284231, 0.2509604, 0.3636076, 0.2584802, 0.3716006, 0.2525428, -0.1997008, 0.0...
[Extrapulmonary tuberculosis].
Each year, there are more than eight million new cases of tuberculosis and 1.3 million deaths. There is a renewed interest in extrapulmonary forms of tuberculosis as its relative frequency increases. Among extrapulmonary organs, pleura and lymph nodes are the most common. Their diagnosis is often difficult and is based...
25,131,362
[ -0.07500468, -0.2959439, 0.1590501, 0.01637521, -0.1946835, -0.3035041, -0.3298488, 0.1991375, -0.113961, 0.05745896, 0.03696219, 0.2275933, 0.3004274, 0.09635589, -0.3529137, -0.277939, -0.1589313, -0.00424475, -0.07541481, 0.3314012, 0.5196231, 0.02002227, 0.0677453, ...
Sustaining dignity? food insecurity in homeless young people in urban Australia.
Food insecurity is recognised as an increasing problem in disadvantaged and marginalised groups. The aim of this study was to investigate issues associated with food insecurity and nutrition in young people experiencing, or at risk of, homelessness in metropolitan Australia. Eight focus group discussions were conducted...
25,131,381
[ -0.3113336, 0.04394563, 0.2670745, 0.01723325, 0.4070797, -0.2236839, -0.1891257, -0.08364727, 0.08447804, 0.1636465, 0.1896816, 0.1843394, -0.5458546, -0.2424736, -0.1312652, -0.1510284, -0.2390371, 0.1516682, -0.1445557, -0.4422883, -0.538181, 0.04947528, -0.2563876, ...
Long-term functional outcomes and quality of life after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer.
Surgery for oral or oropharyngeal cancer with free-flap reconstruction is associated with moderate but persistent functional and quality of life (QoL) problems. Patient age, tumor stage, tumor site, and radiotherapy were the main predictors of functional outcome. To evaluate long-term functional outcomes and QoL, and t...
25,131,390
[ -0.004157237, -0.1246496, -0.001391049, -0.1478142, 0.1002265, -0.423355, 0.3384944, 0.08359608, -0.2041253, 0.1221374, 0.4281811, -0.04826051, -0.4335817, -0.4892203, -0.2178885, -0.5449224, -0.0889656, 0.4397267, 0.05459579, -0.06296626, 0.4879361, 0.3614981, -0.2542273...
Suppression of NGB and NAB/ERabp1 in tomato modifies root responses to potato cyst nematode infestation.
Plant-parasitic nematodes cause significant damage to major crops throughout the world. The small number of genes conferring natural plant resistance and the limitations of chemical control require the development of new protective strategies. RNA interference or the inducible over-expression of nematicidal genes provi...
25,131,407
[ 0.3351817, -0.01465548, 0.1990629, -0.05695518, -0.1872735, -0.1005065, -0.01671957, -0.3190013, 0.2702899, -0.1276343, -0.0601817, -0.02873356, -0.2036224, 0.3575203, -0.4359481, 0.1796447, -0.3742653, -0.08977779, -0.1041397, -0.1928199, 0.2612891, 0.5187493, 0.1803132,...
High doses of benzodiazepine predict analgesic and sedative drug withdrawal syndrome in paediatric intensive care patients.
Critically ill children can develop withdrawal syndrome after prolonged analgesia and sedation in a paediatric intensive care unit (PICU), when treatment is stopped abruptly or reduced quickly. The aim of this study was to evaluate the incidence of withdrawal syndrome in patients after three or more days of analgesic o...
25,131,427
[ 0.04349208, -0.1902506, -0.2560334, -0.3668509, -0.1198957, -0.3784482, 0.1818575, 0.00509493, -0.2384588, -0.1767746, 0.2861642, 0.2119066, -0.01243594, -0.2104399, -0.3374622, -0.006383584, -1.059131, 0.4618098, 0.5600046, -0.01932829, 0.121022, 0.09211615, -0.1384035, ...
Anticonvulsants to treat post-traumatic stress disorder.
We reviewed the existing literature on the efficacy of anticonvulsants in treating post-traumatic stress disorder. We performed a literature search using PubMed, EMBASE and the Cochrane database on 30 September 2013. Randomized,controlled studies that investigated the efficacy of anticonvulsants for post-traumatic stre...
25,131,430
[ -0.1790842, 0.02454688, -0.3141052, -0.1446958, -0.1514142, -0.1434641, -0.05354154, -0.2670422, -0.2530372, -0.2122009, 0.07240771, 0.06104181, 0.1022363, 0.2555673, 0.2302857, -0.2096886, -0.1384311, 0.4147128, -0.0491773, 0.08369596, -0.3486675, 0.2206073, -0.2992301, ...
Involvement of NLRP3 inflammasome in rituximab-induced interstitial lung disease: a case report.
Rituximab is a chimeric anti-CD20 IgG1 monoclonal antibody for the treatment of various forms of lymphoma and haematological autoimmune diseases. Interstitial lung disease is a rare but lethal pulmonary toxicity of rituximab. Nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome is a molecular platfo...
25,131,433
[ -0.1869869, -0.09141257, 0.2818256, -0.2181982, 0.03511917, -0.1192961, -0.03660877, 0.3277587, -0.1858953, 0.04649356, 0.3518618, 0.2302404, -0.3056566, 0.2079564, -0.3979135, -0.1272707, -0.1479824, -0.04424681, -0.06753385, 0.1376735, 0.1909866, 0.6672755, -0.2028802, ...
APRI and FIB-4 are good predictors of the stage of liver fibrosis in chronic hepatitis B: the Chronic Hepatitis Cohort Study (CHeCS).
We aim to determine the predictive ability of APRI, FIB-4 and AST/ALT ratio for staging of liver fibrosis and to differentiate significant fibrosis (F2-F4) from none to minimal fibrosis (F0-F1) in chronic hepatitis B (CHB). Liver biopsy results were mapped to an F0-4 equivalent fibrosis stage. Mean APRI and FIB-4 score...
25,131,445
[ 0.1017923, -0.05489887, -0.04331651, 0.06800348, 0.1431493, -0.2932855, 0.01110317, 0.2297877, 0.004558383, 0.07284292, -0.1649124, -0.3585288, 0.03066452, 0.346463, -0.5427514, -0.6241069, -0.1829426, 0.3433844, 0.01055176, 0.0138353, -0.338116, -0.06927963, -0.2499574, ...
[Characteristics of lymph node metastasis in patients undergoing radical cystectomy for bladder cancer: a retrospective single-center study of 522 cases].
To investigate the characteristics and related influence factors of lymph node metastases in patients undergoing radical cystectomy and lymph node dissection for bladder cancer. The data of 522 patients who underwent radical cystectomy and pelvic lymph node dissection at Department of Urology, Peking University First H...
25,131,462
[ 0.2266469, -0.06212588, -0.3287762, 0.1710748, -0.09239305, -0.3277429, -0.002413025, 0.1120656, -0.2883494, 0.3889418, 0.1413888, 0.3280176, 0.09337498, -0.3117564, -0.2692442, -0.2018083, 0.2399763, 0.2424069, 0.4850953, -0.04792667, -0.08586675, 0.4685904, -0.2920831, ...
[Ureteral stricture following renal transplantation: risk factors and surgical management].
To evaluate the prevalence and the risk factors of the ureteral stricture following renal transplantation and outcomes of surgical managements. By a retrospective analysis, we assessed 1 293 patients who underwent renal transplantation between January 2001 and December 2013 at our center. The patients with ureteral str...
25,131,468
[ 0.1497701, -0.0742761, -0.2826076, 0.0444212, 0.3625196, -0.2851115, 0.002109346, -0.0841459, 0.09076226, 0.2231317, 0.04548686, -0.0623143, 0.05763553, -0.1885119, -0.1461853, -0.2556802, -0.1272187, 0.1075221, -0.01951106, -0.246631, 0.3887999, 0.3525579, -0.09987982, ...
[Diagnosis and treatment of hydrocephalus-accompanied renal calculi complicated with renal tumor: 5 case reports].
To investigate the diagnosis and treatment of renal pelvic tumor combined with renal urinary calculi and hydronephrosis. Five patients with renal pelvic tumor who underwent relief of the upper urinary obstruction were reviewed. One of the cases lost the opportunity of surgical therapy when pelvic tumor was detected at ...
25,131,470
[ -0.08373163, 0.145386, -0.0840251, -0.2007082, 0.1688606, -0.333321, -0.2506635, 0.03985825, -0.00903795, 0.2624312, 0.1367324, 0.4562514, -0.09211764, -0.2234195, -0.3539547, -0.09309372, -0.1300844, 0.238466, 0.04735344, 0.02943823, 0.26262, 0.1925505, -0.1773952, 0.5...
[Analysis for risk factors of systemic inflammatory response syndrome after one-phase treatment for apyrexic calculous pyonephrosis by percutaneous nephrolithotomy].
To investigate the risk factors of systemic inflammatory response syndrome (SIRS) after one-phase treatment for apyrexic calculous pyonephrosis by percutaneous nephrolithotomy (PCNL). Clinical data of consecutive apyrexic calculous pyonephrosis patients who underwent one-stage PCNL from January 2008 to December 2013 we...
25,131,472
[ 0.2818812, -0.05639732, -0.2923627, -0.186016, 0.1041486, -0.01629662, -0.08892735, 0.07193156, 0.1834224, 0.03567394, -0.1466772, 0.05810452, -0.1458129, 0.1727983, -0.02874189, -0.06323281, -0.07644077, 0.2839125, 0.009129859, 0.2618272, 0.3121237, 0.02598839, -0.229321...
[Relationship of genetic variants and cardiovascular risk factors with interleukin-6 and interleukin-10 secreted by monocytes].
To examine the relationship of interleukin (IL)-6 and IL-10 genetic variants and cardiovascular factors [oxygenized low density lipoprotein (ox-LDL), lower physical activity, overweight, etc.] with IL-6 and IL-10 secreted by monocytes. In the study, 40 health persons, aged from 51 to 80 years, without stroke and myocar...
25,131,477
[ -0.2708342, 0.1227892, -0.5097769, 0.04319631, 0.05215281, -0.2064739, -0.3781278, 0.03429943, -0.1924648, -0.3896406, 0.08125338, 0.2918259, -0.06418674, -0.2095412, -0.1680175, -0.01946818, -0.1740066, -0.3116547, -0.2334018, 0.5872765, -0.1115633, 0.06789883, 0.0464081...
[Clinical observation of middle cerebral artery angioplasty in treatment of subcortex cerebral watershed infarction with moderate or severe disabilities].
To assess the safety and effectiveness of middle cerebral artery angioplasty in treatment of subcortical watershed infarcts (S-CWI) with moderate or severe disabilities. From June 2011 to May 2012, 5 S-CWI patients (six lesions) with moderate or severe disabilities combining severe stenosis in Ipsilateral middle cerebr...
25,131,480
[ -0.1724079, 0.2969521, 0.4275536, -0.1565026, 0.01031612, -0.2316677, -0.2879261, -0.2451425, 0.1201329, -0.006309091, -0.0274195, 0.3813228, -0.07248417, -0.1388429, 0.1895699, -0.1213984, -0.03114849, 0.2254662, -0.193689, 0.2317169, 0.00202833, 0.3638315, 0.08966768, ...
[Balloon dilation by B ultrasound monitoring for treatment of urethral stricture: 5 case reports].
Urethral stricture is a common urologic disease and there are many therapeutic methods for it. Here we investigated the application of balloon dilation under B-mold ultrasound monitoring in the treatment of urethral stricture. Five male patients suffering from urethral stricture were treated with balloon dilation under...
25,131,490
[ -0.159523, 0.1968893, -0.1167857, -0.04521412, 0.1648451, -0.2294691, -0.2757789, 0.06880347, 0.02269413, -0.2056417, 0.1128655, 0.03533707, 0.01637073, 0.05569969, -0.0154804, 0.1492797, -0.4764355, 0.3206541, 0.09866235, -0.3853446, 0.3795889, 0.3574545, 0.1318077, 0....
The role of influenza in the severity and transmission of respiratory bacterial disease.
Infections with influenza viruses and respiratory bacteria each contribute substantially to the global burden of morbidity and mortality. Simultaneous or sequential infection with these pathogens manifests in complex and difficult-to-treat disease processes that need extensive antimicrobial therapy and cause substantia...
25,131,494
[ -0.08218192, -0.1777084, 0.00241642, -0.1876557, -0.09656776, -0.3262114, 0.006230185, 0.08654626, 0.05398395, -0.05908873, -0.1527442, -0.300247, -0.1362898, 0.1528443, -0.3697285, 0.03360377, 0.1805213, -0.06716002, 0.03966563, 0.01353715, 0.006477679, 0.1748272, -0.301...
WITHDRAWN: Bronchial-pulmonary adenocarcinoma subtyping relates with different molecular pathways.
This article has been withdrawn for editorial reasons because the journal will be published only in English. In order to avoid duplicated records, this article can be found at http://dx.doi.org/10.1016/j.rppnen.2014.05.006. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Artic...
25,131,502
[ 0.01460529, -0.2056334, 0.1095717, -0.2408405, 0.1087585, -0.1667775, -0.3162652, -0.0944577, -0.02672501, 0.0132006, 0.2197239, 0.1462841, 0.0654899, -0.000802813, -0.3780679, -0.09905323, 0.1506981, 0.0869397, 0.05978857, -0.004441852, 0.04796132, -0.02741943, -0.193567...
A case for the use of autoethnography in nursing research.
This paper discusses the basis for and potential usefulness of autoethnography as a research method in nursing. While qualitative research in nursing has traditionally involved the researcher taking an objective stance, autoethnography, with roots in the social sciences, is an emerging method that examines the research...
25,131,503
[ -0.07259693, -0.1771803, -0.2234876, 0.01735487, 0.2943735, 0.03644691, -0.3318405, -0.3220461, -0.1214015, -0.1376599, -0.2116685, 0.1813393, -0.2825891, -0.4666929, 0.03917221, -0.191595, -0.460759, 0.2814059, -0.2153644, -0.2363861, 0.2436861, 0.2289921, -0.05978342, ...
Spontaneous coronary artery dissection.
Spontaneous coronary artery dissection (SCAD) is a rare but challenging clinical entity of unknown etiology. From a pathophysiological standpoint, SCAD may occur in patients with a coronary intimal tear (presenting with the classic angiographic "flap" and multiple lumens), but also in patients without an intimal ruptur...
25,131,524
[ -0.2912824, 0.1645322, -0.1119263, -0.3225529, -0.06985489, -0.1589497, -0.05406996, 0.1059234, 0.2470706, 0.05637533, 0.2086566, -0.00715497, -0.05594356, -0.4653089, -0.03220399, -0.1009039, -0.4451012, 0.003027259, 0.09808906, 0.1672575, 0.162079, 0.2158516, -0.3533151...
[International comparative study on health condition of young people].
The connection between physical condition, coping strategies and emotional intelligence is widely studied in the international literature, but comparative research data collected among Transylvanian and Hungarian adolescents are not available in contemporary psychological literature. The aim of the authors was to study...
25,131,528
[ -0.1051459, -0.1626546, 0.06546911, -0.1313403, 0.03464329, -0.4518732, -0.4430652, -0.07216182, -0.1631868, 0.1119688, -0.02016565, -0.1128214, -0.09256487, -0.4475074, -0.6980567, -0.12931, -0.512651, 0.2321678, -0.2371264, 0.2353502, 0.05224398, 0.1234572, -0.2859542, ...
Structural and mutational studies on an aldo-keto reductase AKR5C3 from Gluconobacter oxydans.
An aldo-keto reductase AKR5C3 from Gluconobacter oxydans (designated as Gox0644) is a useful enzyme with various substrates, including aldehydes, diacetyl, keto esters, and α-ketocarbonyl compounds. The crystal structures of AKR5C3 in apoform in complex with NADPH and the D53A mutant (AKR5C3(-D53A) ) in complex with NA...
25,131,535
[ -0.08884642, 0.07266895, 0.006199338, 0.1915366, -0.1984352, 0.3291418, -0.06793498, 0.2371439, 0.1833808, -0.1367358, 0.06211938, -0.01777909, -0.1325512, 0.185793, -0.3195391, 0.1106816, -0.5090069, 0.002165867, 0.02855112, 0.1756502, 0.09240933, 0.5084585, -0.04504493,...
Correlates of quality of sexual life in male and female patients with Parkinson disease and their partners.
Patients with Parkinson disease (PD) and their partners may experience a worsening of their sexual life. To assess quality of sexual life (QoSL) in male and female PD patients and their partners. Medical, demographic and clinical data was collected regarding consecutive PD patients, including depression, and motor symp...
25,131,540
[ 0.06699104, 0.3987006, -0.2420135, -0.09020773, -0.01065555, -0.1286698, -0.05531512, -0.06922012, -0.1729134, -0.1287885, 0.05778282, -0.04433351, -0.134988, -0.2308682, -0.3795572, -0.07907476, -0.2521693, 0.1056706, 0.1401538, 0.08801569, 0.08175661, 0.1366216, -0.2034...
Epigenetic regulatory mechanisms in stress-induced behavior.
Stress response is considered to have adaptive value for organisms faced with stressful condition. Chronic stress however adversely affects the physiology and may lead to neuropsychiatric disorders. Repeated stressful events in animal models have been shown to cause long-lasting changes in neural circuitries at molecul...
25,131,544
[ 0.0009132401, -0.1931315, 0.1860683, -0.4087725, 0.01452854, -0.2941, -0.20944, -0.1121014, -0.06519101, 0.1430662, 0.02396914, 0.09908901, 0.1414683, -0.01440442, -0.3468485, -0.001348611, -0.1702173, 0.2081027, 0.05821684, 0.02570825, -0.2465696, 0.1000833, -0.2107888, ...
Smart vesicle kit for in situ monitoring of intracellular telomerase activity using a telomerase-responsive probe.
A smart vesicle kit was designed for in situ imaging and detection of cytoplasmic telomerase activity. The vesicle kit contained a telomerase primer (TSP) and a Cy5-tagged molecular beacon (MB) functionalized gold nanoparticle probe, which were encapsulated in liposome for intracellular delivery. After the vesicle kit ...
25,131,551
[ -0.09370339, 0.4509745, -0.2330119, -0.06709488, 0.0281971, 0.1682893, -0.01345723, 0.1818793, 0.5593567, 0.1243455, -0.05143368, -0.1409796, -0.0988981, -0.006649349, -1.024173, 0.08096563, -0.849202, -0.08454192, 0.1414295, -0.2065475, 0.5500094, 0.3955983, 0.1554577, ...
The object of sexual desire: examining the "what" in "what do you desire?".
Over the past two decades, sexual desire and desire discrepancy have become more frequently studied as have potential pharmaceutical interventions to treat low sexual desire. However, the complexities of sexual desire-including what exactly is desired-remain poorly understood. To understand the object of men's and wome...
25,131,552
[ 0.01272103, 0.1973027, -0.03129143, -0.001682143, 0.1843806, -0.1314564, -0.09425076, 0.163902, 0.2159697, -0.2076205, 0.2212474, -0.206074, -0.2382689, -0.2350797, -0.469253, -0.2524616, -0.3806306, 0.0859343, 0.2712343, -0.2741834, 0.0540208, 0.2018906, -0.276344, -0....
Association of serum uric acid levels to inflammation biomarkers and endothelial dysfunction in obese prepubertal children.
High serum uric acid (SUA) levels are present in patients with metabolic syndrome (MetS), when the latter is associated with endothelial dysfunction, inflammation, and hypertension. This increase in SUA levels may have a key role in cardiovascular diseases. We aim to quantify the differences in inflammation biomarkers,...
25,131,560
[ 0.1593868, 0.08421333, -0.08576614, -0.4578869, 0.2150018, -0.184303, -0.244742, 0.2773691, -0.2131555, -0.1137816, 0.2085244, 0.04867445, -0.261369, -0.07364374, -0.5498953, 0.02006312, -0.2412657, -0.1137363, -0.08496848, 0.3210843, -0.2727695, -0.0610945, -0.5780797, ...
Commercial sexual exploitation and sex trafficking of children in the United States.
Child commercial sexual exploitation and sex trafficking are global health problems requiring a multidisciplinary approach by individuals, organizations, communities, and national governments. The adverse emotional, physical, and social consequences for victims are legion and in many areas of the United States and the ...
25,131,563
[ -0.09629215, 0.09158818, -0.02067053, -0.4852545, 0.01076499, -0.2037081, -0.2717683, -0.2802432, -0.127875, 0.1146668, 0.01633954, 0.06627572, -0.5037838, 0.1835043, -0.002594162, -0.0258613, -0.3746051, 0.1822962, 0.102166, -0.05069525, 0.05469413, 0.2192012, -0.0537275...
Non-small cell lung cancer metastasis to the oral cavity: a case report.
Lung cancer, including non-small cell lung cancer, remains prevalent in Australia and has a very poor survival rate. Metastases to the oral cavity are a rare occurrence that can arise from lung cancers. This case report describes the presentation of a metastatic lesion from a poorly differentiated lung adenocarcinoma o...
25,131,571
[ -0.1571492, -0.1350421, -0.075999, -0.3094751, -0.1744951, -0.06110204, -0.1116955, 0.05952429, -0.2587015, -0.05764806, 0.06959221, 0.5732499, 0.06205525, -0.2981454, -0.09382618, -0.417801, -0.1954524, 0.2334904, 0.4717643, -0.1572968, 0.04731301, 0.2878436, -0.04395591...
Quality of life in caregivers of severely disabled war survivors.
To evaluate quality of life (QOL) of caregivers of severely disabled war survivors and identify variables threatening caregivers' QOL. A cross-sectional study was performed on 532 caregivers of Iran-Iraq war related injured survivors by using Persian version of 36-item Short Form Health Survey (SF-36). Caregivers had l...
25,131,566
[ -0.1408817, 0.08314306, 0.2113199, 0.06823293, -0.3266887, -0.06963149, -0.06502827, 0.3163629, -0.2775869, -0.06719632, 0.2646474, 0.02395314, -0.1620988, 0.03847731, 0.2787885, -0.2819453, -0.4488069, 0.1827786, -0.1210537, 0.1455984, -0.1277916, 0.1646831, -0.02244852,...
Protein folding, misfolding and quality control: the role of molecular chaperones.
Cells have to cope with stressful conditions and adapt to changing environments. Heat stress, heavy metal ions or UV stress induce damage to cellular proteins and disturb the balanced status of the proteome. The adjusted balance between folded and folding proteins, called protein homoeostasis, is required for every asp...
25,131,586
[ -0.2082916, -0.01660844, 0.09338368, -0.167754, 0.02221186, -0.3522726, 0.009510569, -0.06252394, 0.1765654, 0.2942181, 0.1374345, -0.2892936, 0.0009069875, -0.2842832, -0.2772373, 0.2272565, -0.09518464, -0.09998155, -0.3205298, -0.3319468, -0.02036801, 0.2862479, -0.303...
Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents.
Despite the available data regarding antimicrobial activity of phenolic acids, studies dealing with the effects of their metabolites or derivatives are scarce. Therefore, the antimicrobial and demelanizing activities of Coprinopsis atramentaria extract, its organic acids, and methylated and glucuronated derivatives wer...
25,131,614
[ -0.4445772, 0.3776188, 0.2159633, -0.2703339, -0.2386037, -0.08360918, -0.1885408, 0.2982524, 0.1807645, -0.2251491, -0.05214943, -0.192371, 0.08873835, -0.2228603, -0.4877411, 0.5055762, -0.8774282, 0.2862484, 0.3354667, 0.0861045, 0.2179151, 0.2964962, -0.2626067, 0.0...
In vivo quantitative NMR imaging of fruit tissues during growth using Spoiled Gradient Echo sequence.
Nondestructive studies of physiological processes in agronomic products require increasingly higher spatial and temporal resolutions. Nuclear Magnetic Resonance (NMR) imaging is a non-invasive technique providing physiological and morphological information on biological tissues. The aim of this study was to design a ro...
25,131,625
[ -0.3308318, -0.1219602, 0.07134596, 0.02908969, -0.1264394, -0.0349072, 0.1573801, -0.4935693, -0.1971219, 0.08251281, -0.1592014, 0.2302348, -0.02674336, 0.009998647, -0.7939817, 0.0476445, -0.272555, 0.02238698, -0.2510436, 0.06697318, 0.5262634, 0.281751, -0.08992806, ...
Surgical repositioning of a developing maxillary central incisor. A case report.
A traumatic injury to the primary dentition can cause damage to the germ of the permanent successor. As a clinical consequence a dilaceration with root deformation, malpositioning and disturbances of eruption can occur. Surgical repositioning of such a dislocated crown of a developing tooth can be a treatment option. A...
25,131,644
[ -0.1968001, 0.2739959, -0.04381598, -0.1405365, 0.2395156, -0.3378875, -0.3395703, -0.1253236, -0.03450968, 0.2999128, 0.166291, 0.223294, -0.3274534, -0.1671349, -0.2199615, -0.07163102, -0.3818125, 0.3034786, -0.3574913, -0.1052579, 0.1189965, 0.2350279, -0.1578246, 0...
Membrane pathology and microglial activation of mice expressing membrane anchored or membrane released forms of Aβ and mutated human Alzheimer's precursor protein (APP).
Alzheimer's disease and the transmissible spongiform encephalopathies or prion diseases accumulate misfolded and aggregated forms of neuronal cell membrane proteins. Distinctive membrane lesions caused by the accumulation of disease-associated prion protein (PrP(d)) are found in prion disease but morphological changes ...
25,131,655
[ -0.1203068, -0.3739487, 0.008049879, 0.1282682, 0.2124795, -0.3605762, 0.1939849, 0.2128645, 0.0111264, 0.4406573, -0.1702145, -0.07923237, 0.1147196, -0.008341771, -0.1209221, 0.3985549, -0.68584, 0.1027353, -0.1000563, 0.02255364, 0.2230565, 0.2302308, 0.1349937, -0.3...
Factors associated with receiving treatment for dental decay among Medicaid-enrolled children younger than 12 years of age in Iowa, 2010.
The Iowa Department of Public Health I-Smile program provides dental screening and care coordination to over 23,000 low-income and Medicaid-enrolled children per year. The purposes of this study were to evaluate I-Smile program effectiveness to ensure that Medicaid-enrolled children obtained dental treatment after havi...
25,131,658
[ -0.1305894, 0.1066289, 0.1943202, -0.1134691, 0.02756954, -0.1131851, -0.475009, 0.3880404, 0.157446, -0.06967984, 0.04768888, 0.2154934, -0.268787, -0.1635817, 0.003563547, -0.1610209, -0.168477, -0.08499466, 0.02331415, -0.1593324, 0.3041838, -0.1323338, -0.002032784, ...
Trypsinogen activation as observed in accelerated molecular dynamics simulations.
Serine proteases are involved in many fundamental physiological processes, and control of their activity mainly results from the fact that they are synthetized in an inactive form that becomes active upon cleavage. Three decades ago Martin Karplus's group performed the first molecular dynamics simulations of trypsin, t...
25,131,668
[ -0.2831658, -0.1402091, -0.4298251, -0.0112103, 0.1528817, -0.4052243, 0.02588449, 0.102455, 0.315537, -0.04135187, -0.05418323, -0.02781403, -0.04166439, -0.437349, -0.2904028, 0.1161956, -0.3642511, -0.1774409, -0.08679327, -0.003234712, 0.262906, 0.3369811, -0.1078213,...
Self-generated movements with "unexpected" sensory consequences.
The nervous systems of diverse species, including worms and humans, possess mechanisms for distinguishing between sensations arising from self-generated (i.e., expected) movements from those arising from other-generated (i.e., unexpected) movements [1-3]. To make this critical distinction, animals generate copies, or c...
25,131,675
[ -0.003074903, -0.1445958, -0.4060275, -0.2790593, 0.3153149, -0.4138374, -0.4344959, -0.3300398, -0.03182192, -0.09239034, -0.01965929, -0.07117153, -0.0508978, -0.1544723, -0.3859667, -0.008054218, -0.7894109, 0.04878922, -0.09114002, -0.1463203, 0.1372954, 0.1800197, 0....
The iPod binocular home-based treatment for amblyopia in adults: efficacy and compliance.
Occlusion therapy for amblyopia is predicated on the idea that amblyopia is primarily a disorder of monocular vision; however, there is growing evidence that patients with amblyopia have a structurally intact binocular visual system that is rendered functionally monocular due to suppression. Furthermore, we have found ...
25,131,694
[ -0.08370204, 0.04541361, -0.2408276, 0.1178436, 0.2489278, -0.172849, -0.5588755, -0.2241654, 0.1059602, -0.2880271, 0.09457517, 0.07695375, -0.5822253, -0.1656767, -0.1870592, -0.06119211, -0.5294593, 0.5341633, -0.09917682, -0.3942236, -0.005759553, 0.1068352, 0.0171622...
Withdrawal of skeletal muscle cells from cell cycle progression triggers differentiation of Toxoplasma gondii towards the bradyzoite stage.
Toxoplasma gondii is a widespread intracellular parasite of mammals and birds and an important opportunistic pathogen of humans. Following primary infection, fast-replicating tachyzoites disseminate within the host and either are subsequently eliminated by the immune system or transform to latent bradyzoites which pref...
25,131,712
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Assessing the feasibility of hepatitis C virus vaccine trials: results from the Hepatitis C Incidence and Transmission Study-community (HITS-c) vaccine preparedness study.
Efficacy trials of preventive hepatitis C virus (HCV) vaccine candidates raise challenging scientific and ethical issues. Based on data from the first 3 years of a community-based prospective observational study - the Hepatitis C Incidence and Transmission Study-community (HITS-c) - this paper examines the feasibility ...
25,131,726
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TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7.
Toll-like receptors 7 (TLR7) and 8 (TLR8) recognize viral single-stranded RNA and small molecular weight agonists to activate anti-viral immune responses. TLR8s from different species have distinct ligand recognitions. For example, human TLR8 is responsive to ligand stimulation, but mouse and rat TLR8 are activated by ...
25,131,730
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