title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Histochemical changes of the rat testis and epididymis after treatment of alpha-chlorohydrin-effects of a single low dose. | A histochemical study has been made of the localization and changes of lipids, carbohydrates, ATPase and 5'-nucleotidase in fresh and fixed frozen sections of testicular and epididymal components in the normal and alpha-chlorohydrin-treated rats. After treatment with a single low dose of alpha-chlorohydrin, the phospho... | 152,590 | [
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[Tissue specific effect of lymphocytic chalone isolated from rat spleen]. | Chalone-containing alcohol extract from the rat spleen consisting of 8--10 substances of protein nature, according to the data of the disk electrophoresis, possesses a selective property to inhibit the entrance of human transformed lymphocytes into the phase of DNA synthesis. Injection of lymphocytic chalones to the mi... | 152,620 | [
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Some problems of the severely handicapped. | Acceptance of the severely handicapped in our community is limited. It may be limited by lack of experience, as 'the chicken and the egg' syndrome applies--do we keep the handicapped away from the public because of adverse reaction, or does the public react adversely because the handicapped are kept away? I work with h... | 152,625 | [
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Erythrocyte actin and spectrin. Interactions with muscle contractile and regulatory proteins. | Actin and spectrin were isolated from washed red blood cell membranes. Spectrin bound and polymerized erythrocyte actin in the absence of potassium. Spectrin coated into polystyrene latex particles bound 8--9 mol of erythrocyte actin per mol of spectrin when actin was in its depolymerized state. Spectrin enhanced the i... | 152,647 | [
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Studies on the heterogeneity of sarcoplasmic reticulum vesicles. | Isolated sarcoplasmic reticulum vesicles from rabbit white muscle were separated into a light (15--20% of total microsomes) and a heavy (80--85%) fraction by density gradient centifugation. The ultrastructure, chemical composition, enzymic activities and localization of membrane components in the vesicles of both fract... | 152,648 | [
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Properties of three distinct pyrimide transport systems in yeast. Evidence for distinct energy coupling. | In Saccharomyces cerevisiae the uptake of cytosine, uracil and uridine is mediated by three permeases. Using mutants blocked in the metabolic utilization of these three compounds we were able to study their specific uptake. Cytosine and uridine show simple saturation kinetics, whereas uracil uptake is a biphasic proces... | 152,649 | [
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Purification of immunosuppressive factors extracted from bovine spleen (lymphoid chalone). II. Biological activity. | A highly purified extract from bovine spleen (FA) possessing immunosuppressive capacity was studied. Its tissue specificity was analysed in vivo and in vitro and the main components of FA, the well-known nucleosides deoxycytidine, deoxyinosine and thymidine, were tested in vivo. It seems that the molecule responsible f... | 152,670 | [
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Endocrine effects of spironolactone in man. | A double blind, controlled study was carried out in order to investigate the effects of administering spironolactone, 200 mg daily, to five healthy male volunteers. The patterns of change in plasma testosterone (T) and luteinizing hormone (LH) after spironolactone were significantly different from placebo and there wer... | 152,681 | [
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Severe mental retardation in Swedish children born 1959-1970: epidemiological panorama and causative factors. | The findings from two recent Swedish retrospective studies on severely mentally retarded children born 1959-70 are surveyed. One study concerned an average county--Uppsala--in the middle of Sweden, the other a vast northern county, Västerbotten, with a sparse population. Figures for incidence and prevalence are given, ... | 152,701 | [
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Cerebral changes in the course of intoxication with mercury phenylacetate. | A histoenzymic study of cerebral phosphatases and esterases was performed on rats subjected to experimental intoxication with mercury phenylacetate. Following intragastric application of mercury phenylacetate to experimental animals, decreased activities of cerebral ATPase, acP and AChE were observed. The intoxicated a... | 152,713 | [
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[In vitro stimulation of peripheral blood lymphocytes with allogeneic lymphocytes (mixed lymphocyte culture, MLC) or phytomitogens in patients with Hashimoto's thyroiditis (author's transl)]. | To investigate the role of peripheral blood lymphocytes in thyroid auto-immunity, the in vitro responsiveness to allogeneic lymphocytes (MLC) or phytomitogens was examined in the lymphocytes from patients with Hashimoto's thyroiditis. The MLC responses of 16 patients were compared with those of age- and sex-matched nor... | 152,720 | [
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Isolation and characterization of glycerol-3-phosphate dehydrogenase-defective mutants of Neurospora crassa. | Three glycerol-nonutilizing mutants deficient in the mitochondrial glycerol-3-phosphate (G3P) dehydrogenase (EC 1.1.99.5) were isolated from inl(ts) derivatives of Neurospora crassa following inositolless death at elevated temperatures on minimal glycerol medium. These mutants failed to grow on glycerol as a sole carbo... | 152,757 | [
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Chromosome movement in lysed mitotic cells is inhibited by vanadate. | Mitotic PtK1 cells, lysed at anaphase into a carbowax 20 M Brij 58 solution, continue to move chromosomes toward the spindle poles and to move the spindle poles apart at 50% in vivo rates for 10 min. Chromosome movements can be blocked by adding metabolic inhibitors to the lysis medium and inhibition of movement can be... | 152,767 | [
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[Congenital leukomas with anomalies of the lens migration (author's transl)]. | Report of three cases of congenital leukomas with anomalies of the lens migration: first case is an early malformation with "Wedl" cells in the corneal stroma; second case is a Peters' anomaly with ectopic and atrophic lens; third case, with a six years follow up after birthday, shows corneal opacification and regressi... | 152,777 | [
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Macrophage-T cell interactions in the Con A induction of human suppressive T cells. | Macrophage-T interactions are required for the Con A-induced generation of human Ts capable of inhibiting PHA-induced blastogenesis among autologous PBMC. Con A treatment of adherent cell-depleted PBMC, or PBMC recovered after a 7-day incubation in FCS, failed to generate Ts. Addition of adherent cells to either of the... | 152,792 | [
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Genetic identification of a locus linked to the rat MHC that codes for a membrane antigen detectable with cytotoxic lymphocytes. | Cell-mediated cytolytic (CMC) responses resulted from immunizations between rat strains purported to be identical at Ag-B, the major histocompatibility complex (MHC), but differing at other loci not linked to Ag-B. In vivo-priming followed by secondary in vitro stimulation was required to generate a measurable CMC resp... | 152,793 | [
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Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens. | We have studied the modulation of Ia-like antigens on the surface membrane of human T cells responding in a one-way mixed leukocyte culture. A heterologous antiserum, (anti-p23,30), which is specific to HLA-D-related antigens and which is unreactive with normal peripheral T cells or thymocytes, was found to bind signif... | 152,800 | [
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Cross-reactive cytotoxic responses. H-2 restricted are more specific than anti-H-2 responses. | Cross-reactive T-cell cytotoxicity is seen when cytotoxic responses are generated in mixed lymphocyte cultures either between mouse strans which differ at the major histocompatibility complex, H-2, or between H-2b mutant strains and the strain from which they were derived. This cross-reactivity can be measured with [51... | 152,801 | [
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Histological analysis of cat muscle spindles following direct observation of the effects of stimulating dynamic and static motor axons. | 1. Eleven cat tenuissimus spindles have been analysed mainly by cutting serial, transverse, 1 micrometer thick sections following direct observation of the effects of dynamic motor (gamma or beta) stimulation. 2. Histological results from these spindles were also used to interpret the effects of static fusimotor stimul... | 152,810 | [
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The occurrence in mice of facial and mandibular abscesses associated with Staphylococcus aureus. | Swellings affecting the face and jaws of a strain of outbred BSVS mice are described. The swellings consisted of multiple abscesses which were most commonly associated with the mandible. Staphylococcus aureus of a single phage type was isolated from the abscesses. It is suggested that the organisms gained entry through... | 152,826 | [
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The ratio of de novo unbalanced translocation to 47, trisomy 21 Down syndrome. A new method for human mutation surveillance and an apparent recent change in mutation rate resulting in human interchange trisomies in one jurisdiction. | The Down syndrome phenotype may be associated with, among other genotypes, an unbalanced Robertsonian translocation producing an "interchange trisomy" with 46 chromosomes, or 47, trisomy 21. Translocations, like specificlocus point mutations, result from a direct change in structural chromosome elements. In contrast 47... | 152,869 | [
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Unruptured interstitial pregnancy. Diagnosis and treatment. | Symptoms and signs of interstitial pregnancy cannot be differentiated from symptoms and signs of other ectopic pregnancies. Unruptured interstitial gestations are usually diagnosed incidental to the work-up of a suspected ectopic gestation. Unlike some teaching, a characteristic pelvic mass was palpable in 3 of 4 cases... | 152,878 | [
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Thallium-201: quantitation of right ventricular hypertrophy in chronically hypoxic rats. | Sprague Dawley rats were divided into two groups. Ten were kept in room air and 10 in hypobaric hypoxia (air at 380 mm Hg). After two weeks all were injected intravenously with 50 muCi of 201Tl and sacrificed. The right and left ventricles were separated, weighed, and measured for radioactivity in a gamma well counter.... | 152,938 | [
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[The treatment of diaphyso-epiphyseal tumours by local resection with the preservation of joint movement. A report of four cases (author's transl)]. | Four cases of epiphyseal tumours were treated by the authors by local resection. In two cases, there was a giant-cell tumour of the lower end of the femur, in one case a giant-cell tumour of the lower end of the radius and in one case a juxta-cortical sarcoma of the lower end of the radius. In the two cases involving t... | 152,947 | [
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[Upper brachial plexus palsy. Seven cases treated by muscle transplantation (author's transl)]. | Seven cases of upper brachial plexus palsy, have been treated by associated transplantation of pectoralis major for flexion, and of teres major and latissimus dorsi for external rotation. Operation was performed eighteen months at least after injury, during which period rehabilitation was necessary to prevent atrophy o... | 152,948 | [
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A critique of some of the current concepts on the immunopathogenesis of rheumatoid arthritis. | The interaction of polycations produced during tissue damage and C-reactive protein, and the enzymatic degradation of complement components may be positive mechanisms augmenting immune-complex/complement damage, while reduced phagocytosis and reduced chemotaxis may be negative mechanisms. In cell-mediated immunity, sys... | 152,967 | [
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Work and disability at the age of 30 years. A sociomedical study of a birth-cohort from Bergen. III. Disability as related to medical, psychological and educational background. | This article deals with occupational disability at the age of 30 years, seen the light of medical, psychological and educational background. The study is based on a cohort of 1570 persons, all live births in 1940 of mothers then residing in Bergen. This birth-cohort was followed-up in the compulsory school system at ag... | 152,972 | [
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... |
[Electrophoretic studies of acid mucopolysaccharides in skin, prekeratin of hair follicles and in keratoses of wool]. | Mucopolysaccharide complex isolated from skin, prekeratin of hair follicles and keratoses of wool by paper electrophoresis was separated into chondroitin sulphate and hyaluronic acid. The content of chondroitin sulphate in all the objects under investigation except for gamma-keratosis is higher than that of hyaluronic ... | 153,026 | [
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Pressure-flow relationships and pathological changes during renal preservation. | The renal pedicle of one kidney from each of four dogs was ligated for one hour. The contralateral kidney served as a control. Both kidneys were removed and perfused using the "Belzer" technique. Pressure-flow relationships were determined and biopsy samples taken. The vasculature was then injected with silicone rubber... | 153,043 | [
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[Determination of the sensitivity of mycobacteria to pyrazinamide and nicotinamide (author's transl)]. | Since pyrazinamide (PZA) has had a come-back in therapy of tuberculosis a simple and reliable method for sensitivity tests has been necessary. A comparison of resistance tests to PZA in acid Löwenstein-Jensen-medium and in fluid medium with those to nicotinamide (NSA) showed a clear superiority of the NSA method, recom... | 153,062 | [
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... |
[Several principles for epidemiologic evaluation of individual regions of the Trans-Caucasian plains-piedmont natural focus of plague]. | The authors analyse many-year data concerning the epizootological study of seven landscape-geographical regions of the Eastern Transcaucasus differing by natural conditions and the enzootic intensity. Quantitative assessment of natural nidality determined by the level (norm) of many-year indices calculated for the year... | 153,077 | [
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Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity. | Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases. Experimental liver injuries caused a slight decrease in total activity in later stages and a marked increase in a form act... | 153,088 | [
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An interdisciplinary course for optometry students specializing in vision training. | The practice of primary-care optometry often necessitates interaction with professionals from varied backgrounds. This is especially true in the area of vision training, in which close coordination between professionals in schools, agencies, and clinics is necessary. Too often a communcation problem prevents beneficial... | 153,104 | [
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[Lead and cadmium toxicity in established mammalian cell lines]. | Lead and cadmium toxicity was evaluated in three mammalian cell lines (tumour : HeLa, transformed : XC and normal : NRK) by means of the modifications of the 3H-TdR incorporation rate in the nucleus of the treated cells. The three cell lines showed different degrees of sensitivity. Sensitivity depended on the line, met... | 153,166 | [
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[Repartition of the kidney cortex glomerulus in rats]. | This paper presents the repartition of 989 glomeruli in 8 parallel concentric renal cortex zones, by projecting on a calibrated screen rat kidney slices photographies. The glomerular density increases regularly from the outside to the middle cortical zones and then decreases to the deepest juxtamedullary zones. | 153,171 | [
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[Localization of N-acetyltransferases in sinusoidal liver cells. Effect of zymosan on the acetylation of sulfamethazine and isoniazid in the rat and in isolated perfused liver]. | N-acetyltransferase (NAT) have been demonstrated to be localized in sinusoïdal cells and not in hepatocytes. Acetylation activities increased after pretreatment with Zymosan (40 mg/kg, i.v., 24 h before phenotyping) as well in vivo and in isolated perfused liver and in cytosolic fractions prepared from several rats org... | 153,185 | [
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Assembly of the mitochondrial membrane system: mutations in the pho2 locus of the mitochondrial genome of Saccharomyces cerevisiae. | Two mutants of Saccharomyces cerevisiae which show a loss of mitochondrial rutamycin-sensitive ATPase activity are described. Although phenotypically similar to mutants of the mitochondrial locus pho1 [F. Foury and A. Tzagoloff (1976) Eur. J. Biochem. 68, 113-119], these mutants define a second ATPase locus on the mito... | 153,229 | [
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Studies of cultured human fibroblasts in diabetes mellitus: changes in heparan sulfate. | The incorporation of [35S]sulfate into glycosaminoglycans was studied in cultures of normal and diabetic skin fibroblasts. Heparan sulfate was determined by column chromatography after enzymatic degradation of chondroitin sulfates and dermatan sulfate by chondroitinase ABE. Cultured skin fibroblasts from both insulin-d... | 153,251 | [
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[Osteoarthritis in the neonate. Radiologic diagnosis and follow-up observations (author's transl)]. | A fatally ending index case of septic osteoarthritis that was diagnosed retrospectively initiated this report. This patient had severe, asymmetrically distributed metaphyseal growth disturbances at many long bones. In order to determine the features of early radiologic diagnosis we report the findings of 7 further pati... | 153,314 | [
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Complement activation in acne vulgaris: in vitro studies with Propionibacterium acnes and Propionibacterium granulosum. | To better define the role of bacteria in inflammatory acne vulgaris, we have investigated the ability of four strains of Propionibacterium acnes and three strains of Propionibacterium granulosum to activate complement. Complement activation was assayed by incubating normal human serum with varying concentrations of eac... | 153,333 | [
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Reflex conditioning in a spinal man. | A man with a completely transected spinal cord and a spastic neurogenic bladder was conditioned to void upon the presentation of an external stimulus. A classical conditioning paradigm was employed in which strong abdominal shock (unconditioned stimulus) was paired with an initially neutral mild electrical stimulation ... | 153,348 | [
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Myotonia in centronuclear myopathy. | Centronuclear myopathy, which is unusual because of clinical myotonia, is described in two sisters. The diagnosis was established in adult life, but the first symptoms were noticed in infancy. The outstanding points of the clinical picture were mild amyotrophy, paresis, and clinical myotonia. | 153,383 | [
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Medicine and disability--a broader view. | This paper seeks to emphasise the social approach in the treatment of disability. It is important that disabled people should lead as near a normal life as possible with some financial security. Financial assistance for disabled people is left up to individual local authorities. The author points out the disadvantages ... | 153,404 | [
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Prolonged remissions of cystic and conglobate acne with 13-cis-retinoic acid. | Fourteen patients with treatment-resistant cystic and conglobate acne were treated for four months with oral 13-cis-retinoic acid, a synthetic isomer of naturally occurring all-trans-retinoic acid. The average dose was 2.0 mg per kilogram per day. Thirteen patients experienced complete clearing of their disease; the ot... | 153,472 | [
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Accumulation of a tetrahydroisoquinoline in phenylketonuria. | 3',4'-Deoxynorlaudanosolinecarboxylic acid (DNLCA), a tetrahydroisoquinoline derived from dopamine and phenylpyruvic acid, has been detected by computerized mass fragmentography in urine of phenylketonuric children and in urine and brain of rats with experimentally induced hyperphenylalaninemia. Levels of DNLCA in brai... | 153,583 | [
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Peritoneoscopy in the management of breast cancer. | Peritoneoscopy has been recommended by the Combined Breast Clinic at the Provincial Hospital, Port Elizabeth, since 1975, mainly to confirm or exclude metastatic involvement of the liver. Experience with 27 procedures is reviewed. Peritoneoscopy is shown to be a useful aid in the staging and management of selected case... | 153,589 | [
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Cerebral neuroblastoma. | A cerebral neuroblastoma removed surgically from a female child is presented. Electron microscopy showed numerous neuronal processes with growth cones which are a feature of the developing neurone. In addition there were some rosettes with distinct lumina. The luminal surfaces were covered with a smooth plasma membrane... | 153,641 | [
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[Phosphoenolpyruvate carboxykinase in Phycomyces blakesleeanus Bgff. (author's transl)]. | Phosphoenolpyruvate carboxykinase (PEPCK) from Phycomyces blakesleeanus was partially purified by protamine sulfate precipitation, ammoniumsulfate precipitation, and diethylamino ethyl cellulose (DEAE) treatment. This preparation was employed for the characterization of the enzyme. The Km values for phosphoenolpyruvate... | 153,664 | [
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[Animal experiment studies on the effect of intra-articular injections of antiphlogistic-antirheumatic agents on articular cartilage in vivo]. | Animal experiments have shown that weekly intraarticular injections of various antiphlogistic/antirheumatic drugs into the knee joint induce progressive degenerative alterations in joint cartilage. The observed degenerations and destructions are most similar to the pathophysiology of osteoarthrosis in humans. By X-ray ... | 153,678 | [
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Relationships between association state and enzymic activity of human erythrocyte phosphofructokinase. | Human erythrocyte phosphofructokinase has been subjected to active band centrifugation and stability measurements over a broad range of conditions. The enzyme behaves differently in-Tris buffer containing ATP and phosphate buffer containing fructose 6-phosphate. In the first buffer, dissociation is favoured and after p... | 153,694 | [
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Electron microscopic localization of Mg2+ -dependent adenosine triphosphatase activity in the amphibian pancreas (Salamandra salamandra L. and Rana esculenta L.). | The ultrastructural distribution of Mg2+ -dependent adenosine triphosphatase (ATPase) activity has been investigated in the salamander and frog pancreas by using glutaraldehyde fixations and a modified Wachstein-Meisel reaction medium. In both species the reaction product (lead phosphate) was found associated with the ... | 153,700 | [
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Relationship of atrial fibrillatory wave amplitude to left atrial size and etiology of heart disease. An old generalization re-examined. | It is commonly stated that coarse f waves in atrial fibrillation suggest the presence of rheumatic heart disease and large left atrial size, whereas fine f waves indicate non-rheumatic disease and small left atrial size. Using echocardiography as a more reliable indicator of left atrial size, 37 consecutive patients wi... | 153,707 | [
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... |
Iodochlorhydroxyquin-hydrocortisone treatment of fungal infections. Double-blind trial. | A double-blind multicenter study compared the antifungal effectiveness of an iodochlorhydroxyquin-hydrocoritsone cream with that of its individual components in 354 patients with cutaneous fungal infections. After seven days of treatment, the combination was considerably better than hydrocortisone or the cream vehicle ... | 153,729 | [
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... |
Ionic charge on phospholipids and their interaction with the mitochondrial adenosine triphosphatase. | The activity of the lipid-depleted, oligomycin-sensitive mitochondrial ATPase has been measured in the presence of liposomes prepared from mixtures of phosphatidylglycerol and phosphatidylglycerol lysine. Enzyme activity increased linearly with an increase in the negative charge of liposomes prepared from the phosphati... | 153,765 | [
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[Beckwith Wiedemann syndrom (author's transl)]. | In connection with four new observations and a revue of 82 cases published the mains features of Beckwith-Wiedeman syndrom are described insisting on the neonatal troubles of the glycoregulation upon the structural development of the childrens and on the pathologics associations. | 153,802 | [
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A new biochemical subtype of the Sanfilippo syndrome: characterization of the storage material in cultured fibroblasts of Sanfilippo C patients. | Fibroblasts cultured from the skin of three unrelated patients with the clinical symptoms of the Sanfilippo syndrome (mucopolysaccharidosis III) accumulated intracellularly excessive amounts of heparan sulfate and showed a lengthened turnover time for this mucopolysaccharide. They exhibited, however, neither a deficien... | 153,835 | [
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Selective excitation of mithramycin or DAPI fluorescence on double-stained cell nuclei and chromosomes. | Fluorescence spectra of leukocytes stained by both mithramycin and DAPI showed that the fluorescence of the two dyes can be separated efficiently by using different excitation wavelengths, for instance the 435 nm and the 365 nm mercury lines. In human chromosomes the complementary ("reverse") banding pattern produced b... | 153,894 | [
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Laparoscopy in zoological medicine. | The technique of laparoscopy was adapted and utilized in zoological medicine for various mammals, birds, and reptiles for reproductive and diagnostic studies as well as clinically related research. It was concluded that since anesthesia was routinely required for most manipulative procedures in zoo animals, and since l... | 153,896 | [
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Attitudinal differences of faculty and students regarding the care of special (handicapped) patients in a dental school clinic. | Faculty and students were surveyed as to their attitudes regarding the management of the special patient. This survey was completed after such a program was in existence for three years. Recommendations were made to better realize the overall goals of the program, especially that of encouraging the treatment of the spe... | 153,921 | [
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Characterization of the plasma membrane ATPase of Saccharomyces cerevisiae. | 1. The distribution of ATPase and several marker enzymes was examined after differential and sucrose gradient centrifugation of yeast homogenates. 2. An ATPase activity not sensitive to oligomycin is found exclusively associated with a particulate fraction equilibrating at densities of 1.23-1.25. This particulate mater... | 154,059 | [
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The role of methylprednisolone in the modulation of cellular cytotoxicity and its relation to renal transplantation. | Inhibition of killer cell generation or suppression of their cytolytic capacity once formed represent fundamental mechanisms by which methylprednisolone may modulate cellular cytotoxicity in the transplant recipient. In vitro studies in mixed lymphocyte culture demonstrated that the presence of therapeutic concentratio... | 154,100 | [
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Midabdomen abdominoplasty. | A simple technique is presented for removal of excessive supraumbilical and periumbilical skin. | 154,114 | [
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ATPase, an electron carrier and energy transducer: the missing link in oxidative phosphorylation? | A mechanism for oxidative phosphorylation is proposed. ATP synthesis would take place on a catalytic site of ATPase constituted by two irons with ligands ATP, ADP, and Pi. The interchange of ATP with ADP and Pi makes possible a redox cycle between two potentials permitting the energy transduction. | 154,160 | [
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Spinal fusion for chronic low back pain. | Results of spinal fusion for chronic low back pain in 46 patients are analyzed, and the authors set forth the clinical circumstances in which the procedure may relieve this common complaint. | 154,237 | [
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Growth and myelination of goldfish optic nerve fibers after retina regeneration and nerve crush. | Axonal regeneration in the optic nerve and tectum of the goldfish was studied both after retina regeneration and nerve crush. The retina regeneration was evoked by ouabain-induced damage of at least the ganglion cells and cells of the inner nuclear layer. The necrotic retinal neurons are substituted by mitotic processe... | 154,235 | [
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[Urological problems and genesis of the abdominal musculature aplasia syndrome]. | Judging according to the frequent description of the syndrome of aplasia of the abdominal muscle above all in paediatric literature (up to now more than 250 cases), the knowledge of the symptomocomplex (aplasia of the abdominal muscle, malformations of the kidneys and the urinary tracts, cryptorchism) might be of parti... | 154,249 | [
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[Periodontal disease in the workers of paints and lacquer industry (author's transl)]. | Examinations were performed by the author upon the influence of organic solvents and polycyclic aromatic hydrocarbons on parodontium in the workers of paints and lacquer industry. 195 persons employed in industry were examined. 100 persons whose conditions of work had no influence on their parodontium served as control... | 154,253 | [
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The proliferative activity of myocardial capillary wall cells in variously aged swimming-exercised rats. | Cellular proliferation was studied by incorporation of 3H-thymidine in the hearts of young, adult and old swimming-exercised rats. The proliferative activity was measured by scintillation counting. The swimming exercise induced a significant proliferation of capillary wall cells in the younger age groups, suggesting a ... | 154,282 | [
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The effects of thymoxamine on anterior chamber depth in human eyes. | The effects of 0.5% Thymoxamine on intraocular pressure and anterior chamber depth were studied in 20 non-glaucomatous eyes. Miosis occurred in all of the eyes but was not accompanied by a shallowing of the anterior chamber or reduction in the intraocular pressure. The significance of the findings is discussed. | 154,360 | [
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A comparative trial of two oral cholecystographic contrast media--iocetamic acid (Cholebrin) and iopanoic acid (Telepaque). | A comparative trial was made between two oral cholecystographic agents, iocetamic acid (Cholebrin) and iopanoic acid (Telepaque), Fifty patients were given Cholebrin and another 50 were given Telepaque by random allocation. The cholecystographic qualities of the two contrast media showed no significant difference. It w... | 154,372 | [
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Molecular transformations in sarcoplasmic reticulum of fast-twitch muscle by electro-stimulation. | Chronic electro-stimulation of fast-twitch rabbit muscle with the frequency pattern received by a slow-twitch muscle induces a progressive transformation of the sarcoplasmic reticulum. After 2 days stimulation activities of Ca2+-dependent ATPase and of Ca2+ transport begin to decrease, and are paralleled by a progressi... | 154,404 | [
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[Effects of a new psychotropic agent, CS-430, on the central nervous system of experimental animals (author's transl)]. | In rats and rabbits with chronically implanted electrodes CS-430(10-bromo-2, 3, 7, 11b-tetrahydro--11b-(2-fluorophenyl)-oxazolo(3, 2d) [1, 4]benzodiazepine-6(5H)-one) (3 mg/kg, .o.) decreased the slightly awake period and increased the slow-wave sleep period. The onset time of sleep was significantly shortened. In the ... | 154,438 | [
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[Computer tomographic densitometry of human blood. The effect of absorption by parenchymatous organs and effusions (author's transl)]. | In vitro measurements of human blood with varying haemoglobin and plasma concentrations have shown a linear relationship between haemoglobin concentrations and attenuation values. A change of haemoglobin content of 1 g/100 ml. blood produced and equivalent density change of 1.5 HU. Attenuation of normal blood is betwee... | 154,448 | [
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Role of granulocytes in immune complex-induced tissue injuries. | Tissue injury of many types may be caused by deposited complexes of antigen and antibody. The circumstances under which the complexes form and deposit often determine the location and type of injury observed: If the complex forms in the circulation, deposition may occur in arterial walls and glomeruli, initiating lesio... | 154,471 | [
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Papillon-Lefevre syndrome. | Two cases of Papillon-Lefevre Syndrome (PLS) in a family are reported. Association of recurrent infections, arachnodactyly, intracranial calcification and phalangeal abnormality have been observed. Because there is no history of consanguinity, and autosomal recessive pattern of inheritance is suggested. | 154,478 | [
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[Hyperosmolar nonketotic diabetic coma in children]. | Nonketotic hyperosmolar diabetic coma is a rare manifestation of juvenile diabetes, in contrast to adult onset diabetes. To date only 20 cases have been published, the majority of them infants and toddlers. This type of diabetic coma is seen with unusual frequency in children with Down's syndrome and psychomotor retard... | 154,487 | [
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On the reduced intercellular adhesiveness of virally transformed BHK21 cells. | Baby hamster kidney fibroblasts (BHK21 cells) transformed by polyoma or Rous sarcoma viruses aggregate less than the untransformed parental cells when incubated in growth medium in a gyratory shaker for 18-24 h. This difference can be measured by electronic particle counting, or by filtering aggregated suspensions of 3... | 154,524 | [
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Inflammatory seborrheic keratoses with mononuclear cell infiltration. | Inflammation in inflammatory seborrheic keratoses was found to be composed of mononuclear cells, particularly lymphocytes. Accumulations of mononuclear cells in the papillary and subpapillary dermis frequently showed no tendency to infiltrate the epithelium. However, dramatic interaction of the seborrheic keratosis and... | 154,526 | [
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Hospitals for the mentally ill and handicapped in Melbourne Australia. | This report of visits made while on a Churchill Traveling Fellowship briefly outlines some catering problems in caring for the mentally ill and handicapped. | 154,535 | [
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Cross-linking of the (Ca2+ + Mg2+)-ATPase protein. | The addition of cupric-1,10,-phenanthroline, a cross-linking catalyst, to sarcoplasmic reticulum membranes caused protein sulfhydryl groups to form disulfide bridges. Following a short exposure to the catalyst (15 s, 22 degrees C) most of the protein was in a dimeric form (Mr = 248,000). Longer exposure times resulted ... | 154,538 | [
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The breeding and use of specific pathogen-free (SPF) rats. | Bronchiectasis is common in older rats and is a serious complication when the lungs are repuired for research purposes. SPF rats do not develop this complication, but special isolated accommodation must be provided and care of the animals must avoid introduction of outside micro-organisms. Animals removed from the isol... | 154,574 | [
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[Bacterial overgrowth of slides and electron microscopic grids in the surface film of water and ooze deposits]. | Distinct bacterial growth can be discerned in the surface water film on semisubmerged slides in the laboratory conditions. The thickness of growth depends on the content of organic substances in water. The growth is found also in natural brine if the content of salts is 127--230 g per litre. A great variety of aqueous ... | 154,612 | [
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Alkaline deoxyribonucleases released from Neurospora crassa mycelia: two activities not released by mutants with multiple sensitivities to mutagens. | Three major alkaline deoxyribonuclease (DNase) activities have been identified in sorbose-containing liquid culture medium in which wild-type Neurosporacrassa were grown: DNase A, a Ca++dependent endonuclease of molecular weight 65,000 daltons which has no specificity for single- or double-stranded DNA (ss-DNA or ds-DN... | 154,656 | [
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-0.2943557,
... |
The effect of EDTA on the histochemical myofibrillar ATPase reaction. | The effects of different salts and concentrations of ethylene diamine tetraacetic acid (EDTA) on the histochemically demonstrable myofibrillar ATPase reaction have been investigated. Serial frozen sections from the vastus lateralis muscle of rats, rabbits and guinea pigs were treated with cold (4 degrees) dipotassium E... | 154,688 | [
-0.1485388,
0.1344038,
-0.2608407,
0.1978646,
0.06377867,
-0.3968553,
0.07080822,
0.2834,
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0.03897138,
0.2326732,
0.5488976,
0.2971396,
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0.04906214,
-0.2211427,
0.1588308,
0.3531734,
0.1628233,
-0.1364328,
-0.14... |
Natural oestrogen in the female climacteric--influence on blood coagulation and fibrinolysis. | The aim of the present study was to investigate the effect on blood coagulation and fibrinolysis of a natural oestrogen preparation, piperazine oestrone sulphate, prospectively in menopausal women. Scopolamine was given to the control group. The women were investigated before and during treatment with regard to factors... | 154,749 | [
-0.009711417,
0.122029,
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-0.1091447,
0.01826242,
-0.05322481,
0.2943566,
0.2461949,
-0.3447307,
0... |
An approach to nutritional therapy of hepatic encephalopathy by normalization of deranged amino acid patterns in serum. | A mixture with essential and nonessential amino acids high in branched chain amino acids and low in aromatic amino acids (Fischer solution), and another synthetic mixture of branched chain amino acids containing 3 amino acids associated with the urea cycle (Hep-OU) were infused to control subjects and patients with sev... | 154,828 | [
-0.225401,
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0.1866973,
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0.05577932,
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0.1539734,
0.1435042,... |
The athlete's heart. | In summary, we have discussed the anatomical and physiologic effects of physical training and how they alter the physical examination, thoracic roentgenogram, ECG, and echocardiogram of the athlete. The importance of recognizing these deviations from "normal" findings is to avoid considering them evidence of cardiac di... | 154,831 | [
-0.4515863,
0.07155282,
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0.2356884,
0.2359886,
0.008198864,
0.1434681,
0.3873849,
-0.2039768,... |
HL-A and hypertrophic cardiomyopathy. | HL-A antigens were determined in 26 unrelated Japanese patients with hypertrophic cardiomyopathy. Several antigens were more common in patients compared with controls, but statistically significant differences were not evidenced. We also studied two families in which many had a hypertrophic cardiomyopathy. All the affe... | 154,832 | [
0.02135445,
0.1167833,
0.04726731,
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0.05691445,
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0.1451575,
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0.04040078,
0.1867593,
0.4269087,
0.2532459,
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-0.0526265,
0.2546367,
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0.3585488,
0.1590739,
-0.447006,
... |
Visual handicaps of mentally handicapped people. | Recent literature concerning visual handicaps of mentally handicapped people was reviewed. Topic areas considered were etiology and epidemiology, visual acuity, color vision, and educational techniques. The material considered indicated that a large proportion of mentally handicapped people are affected by some form of... | 154,844 | [
-0.3341969,
-0.05595658,
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0.1474499,
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0.1387917,
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0.05127707,
0.3293929,
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-0.4353256,
0.2576866,
-0.3768375,
-0.0801107,
0.1203009,
0.4276267,
-0.126942... |
Hypertrophic cardiomyopathy in the dog. | Clinical and necropsy findings in 10 dogs with a spontaneous primary hypertrophic cardiomyopathy are described. Each dog had marked cardiac hypertrophy, and 8 dogs had disproportionate thickening of the ventricular septum with respect to the left ventricular free wall (compared with dogs with normal hearts or with card... | 154,845 | [
-0.4234282,
0.1800251,
-0.03920785,
-0.1217899,
-0.08635452,
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0.2629072,
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0.2278822,
0.2670474,
-0.3368509,
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0.1430141,
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0.4345772,
0.3719467,
-0.2010874,
0.04660725,
0.2207321,
-0.3097189,
... |
Histochemical characteristics of the masseter and temporalis muscles of the rhesus monkey (Macaca mulatta). | The histochemical characteristics, cross-sectional area and capillary of the skeletal muscle fibers of the anterior and posterior regions of the superficial masseter and the temporalis muscles are described for juvenile and adult rhesus monkeys of both sexes. Slow twitch fatigue resistant (S), fast twitch fatigue resis... | 154,857 | [
0.1385642,
0.07961261,
-0.2698748,
0.006469881,
-0.01211666,
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0.04215616,
0.05308992,
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0.2371933,
0.2344588,
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0.04948244,
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-0.3868358,
-0.04231216,
0.1269089,
-0.006829374,
0.4498281,
-0.0929095,
-0.2... |
Newly acquired left bundle-branch block: the Framingham study. | The clinical implications of newly acquired left bundle-branch block (LBBB) were examined prospectively in the Framingham Study population. During 18 years of observation 55 people developed LBBB. The mean age at the onset of LBBB was 62; LBBB occurred largely in people with antecedent hypertension, cardiac enlargement... | 154,870 | [
-0.2090038,
0.1307847,
-0.528442,
-0.01362307,
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0.2564218,
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-0.1503131,
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0.4289735,
-0.1065637,
-0.222536,
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-0.216787,
0.1077307,
0.03204973,
0.03654046,
0.07804979,
0.3127896,
-0.298... |
[Clinical evaluation of a topical ethyl lactate treatment of acne vulgaris (author's transl)]. | The efficacy of a lotion containing 10 p. 100 ethyl lactate was evaluated in a double-blind clinical trail during 8 weeks. Test subjects were 45 male and female patients with polymorphous juvenile acne. They were divided into three groups and received the following treatments: Group A: oral antibiotic + topical placebo... | 154,872 | [
0.2219939,
0.09392934,
0.0706965,
0.09137794,
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-0.3697225,
-0.2729352,
-0.1257169,
0.05267734,
-0.09644699,
-0.07864223,
0.1996567,
0.1659607,
0.06991356,
-0.3739256,
-0.1965888,
-0.6441461,
0.1461604,
0.1108684,
0.5035971,
0.4988039,
0.1618272,
-0.001331063,
... |
The value of the electromagnetic flow probe in experimental and clinical microvascular anastomosis. | The Gould Statham Blood Flowmeter Model SP 2204 has been used to assess microanastomosis in 25 superficial femoral arteries of rabbits. When a pulsatile wave form has been achieved this correlates with a satisfactory anastomosis and vice versa. The digital read out of estimated volume flow past the anastomosis made by ... | 154,876 | [
-0.254967,
-0.037494,
-0.1805106,
-0.151618,
-0.04177648,
-0.3307772,
-0.2227309,
-0.02610523,
-0.2574143,
0.03620268,
0.09748024,
-0.02931735,
-0.3219679,
-0.3038742,
-0.3073402,
-0.1560141,
-0.1520916,
0.1848681,
-0.1056608,
-0.04192667,
0.5316268,
-0.001354521,
0.14712... |
Photosensitivity of respiration in Neurospora mitochondria. A protective role for carotenoid. | 1. The effect of visible light on respiratory activity was studied in two strains of Neurospora crassa, one a wild-type strain able to synthesize carotenoid and the other an albino mutant lacking carotenogenic activity. Light had no effect on growth under the conditions studied, but inhibited respiration of hyphal susp... | 154,887 | [
-0.2579996,
-0.08501785,
-0.1075429,
-0.167621,
0.1612229,
-0.1948148,
-0.06573101,
-0.001598639,
0.4532184,
-0.2086421,
0.2067856,
0.04221642,
-0.1780444,
-0.2102661,
-0.3816017,
0.3390636,
-0.5788939,
-0.09899478,
-0.2059822,
-0.05840702,
0.1918634,
0.4703956,
-0.070082... |
Comparative antiinflammatory and bone protective effects of two diphosphonates in adjuvant arthritis. | The effects of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) and disodium dichloromethane diphosphonate (Cl2MDP) were evaluated in the rat adjuvant model of arthritis to directly compare their ability to inhibit arthritic processes. The results of the experiment indicated that both diphosphonates inhibited osseous... | 154,893 | [
-0.2862982,
0.1489682,
-0.05619611,
-0.207165,
-0.2215896,
-0.1561388,
-0.1234417,
-0.05972495,
-0.1392189,
-0.1777703,
-0.0982153,
0.07704652,
0.3163691,
-0.1387352,
-0.6081048,
0.06720875,
-0.292096,
-0.0120793,
0.2369755,
0.7088495,
-0.1590262,
-0.156115,
-0.2004353,
... |
[Hemodynamic, functional and biochemical effects of hypobaric hypoxia in rats treated with cytidine diphosphocholine]. | Treatment with cytidine diphosphocholine (20 mg/kg i.p.) in rats induces, during acute hypoxia, a reduction of vegetative responses (no modification of cerebral blood flow), a protection of conditioned avoidance response and a stabilization of dopamine and noradrenaline cerebral levels. | 154,945 | [
-0.08388321,
-0.1008554,
0.01332017,
-0.1192212,
0.2100699,
-0.4347728,
-0.3042105,
-0.27406,
-0.1864165,
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-0.03186094,
0.3807062,
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0.05530505,
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0.1559905,
-0.121659,
0.3788649,
-0.04865667,
0.02501483,
0.06771846,
... |
[Cellular material in urinary sediment in retarded or precocious puberty]. | The cellular material studied in the urinary sediment mainly obtained from exfolied alls the bladder trigone was submitted to hormonal stimulation. These cell changes constitute the basis of a cytologic method called the urocytogram. The urocytogram was followed up in six children with early puberty and ten young girls... | 154,955 | [
-0.1820507,
0.1165868,
-0.1131683,
0.08434797,
0.1834515,
-0.453312,
-0.4264338,
-0.05705297,
0.06260804,
0.278061,
0.1464864,
0.5929078,
-0.3032874,
-0.0007290657,
-0.7359525,
-0.0305554,
-0.09493371,
-0.08031461,
-0.2272156,
-0.01268387,
0.8164114,
-0.1693311,
-0.037196... |
Differences in the constitution and distribution of acidic glycosaminoglycans in the intimal and adventitial layers of bovine aorta. | Differences in the constitution of acidic glycosaminoglycans (AGAG) in the intimal layer and in the adventitia of bovine aorta were demonstrated by means of enzymatic assay and electrophoretic characterization after fractionation by ion-exchange chromatography and by gel filtration. The data obtained after ion-exchange... | 154,984 | [
0.2599455,
0.2583697,
-0.3889193,
0.3199189,
0.07433112,
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0.2426554,
0.07331796,
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0.2811575,
0.004679979,
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0.02748236,
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0.3511693,
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0.07094457,
-0.1370426,
0.542989,
0.2934796,
-0.07370092,
0... |
Adrenarche: a survey of rodents, domestic animals, and primates. | The concentrations of the adrenal steroids dehydroepiandrosterone (DHA), dehydroepiandrosterone sulfate (DHAS), and delta 4-androstenedione (delta 4-A) have been measured by RIA before and after sexual maturation in plasma of rodents, domestic animals, and primates to determine whether these species exhibit and adrenar... | 155,005 | [
-0.08179341,
0.05648651,
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-0.4438617,
0.1225836,
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0.1820645,
0.06802306,
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0.3277017,
0.01001908,
0.1702384,
-0.3509825,
-0.4189666,
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-0.1684315,
0.2712854,
0.3385281,
0.01625771,
0.3188503,
0.1836993,
-0.1897794,
-... |
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