title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Cellular adaptations of the ventilatory muscles to a chronic increased respiratory load. | It is not known whether cellular adaptations of the ventilatory muscles are induced by increased respiratory loads. A chronic respiratory load was produced in rats by tracheal banding. Five weeks after the imposition of this increased load, biochemical and histochemical analyses were performed on the diaphragm and inte... | 149,778 | [
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The effects of storage of sarcoplasmic reticulum fragments on the Ca2+, Mg2+-ATPase. | The effects of K+ and Na+ on the Ca2+,Mg2+-ATPase of sarcoplasmic reticulum fragments (SRF) were investigated at 1 mM ATP. There was an alteration of the sensitivity of the ATPase to the monovalent cations during storage of the SRF preparation. The Ca2+, Mg2+-ATPase of freshly prepared SRF was slightly activated by 5-1... | 149,789 | [
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Effect of light and oxygen on neocarzinostatin stability and DNA-cleaving activity. | The in vitro DNA-cleaving activity of neocarzinostatin, a protein antibiotic, is strongly but reversibly inhibited by anaerobiosis. Half-maximal activity is seen in the presence of 0.25 mM O2. The stability of neocarzinostatin, as demonstrated by its ability to cleave DNA, is significantly reduced in light. Inactivatio... | 149,790 | [
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Sonographic findings in gastroschisis. | The antenatal sonographic appearance of gastroschisis is described. The findings consist of numerous extra-abdominal "cystic masses" respresenting loops of fluid-filled bowel eviscerated through the abdominal defect. This patient also had associated polyhydramnios, possibly on the basis of a functional bowel abnormalit... | 149,801 | [
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[Dominant cystoid macular dystrophy (author's transl)]. | Dominant cystoid macular dystrophy (D.C.M.D.) is characterized by a macular dystrophy but at the same time by a pigmentary dystrophy of the retinal periphery. Ultimately D.C.M.D. resembles an atypical pigmentary dystrophy, in some cases that of a pericentral retinitis pigmentosa. In an early stage the results of the EO... | 149,806 | [
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Risks of manifestation of Huntington chorea. | A methodology allowing the estimate of risks heterozygosity and manifestation of Huntington's chorea (HC) within preestablished periods for individuals of any age was developed. For this, the procedure was the following: 1. The variables which could influence the distribution of age frequencies were studied. 2. The err... | 149,840 | [
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A critical assessment of fluid requirements in gastroschisis. | This report critically evaluates the fluid requirements of 30 infants with gastroschisis. Fluid requirements were unrelated to gestational age, birth weight, or type of repair. Twenty-five percent of the fluid was colloid needed to restore intravascular volume and oncotic pressure, the balance consisting of Ringer's la... | 149,844 | [
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[Direct examination in immunofluorescence of temporal artery sections. Value and limitations (author's transl)]. | Although invariably seen with immunofluorescence in Giant Cell Temporal Arteritis, deposits of immunoglobulins and complement in the wall of the temporal arteries is nevertheless not specific to his condition. The results of the preliminary study reported here would seem to indicate that this phenomenon is related to t... | 149,956 | [
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Two fragments from fibrinolysin digests of ovine prolactin: characterization and recombination to generate full immunoreactivity. | The action of fibrinolysin (plasmin; EC 3.4.21.7) on ovine prolactin has been investigated. It was found that the enzyme selectively cleaves the bond between Met-53 and Ala-54. The two fragments, PRL-(1-53) and PRL-(54-199), have been purified and characterized. A recombinant molecule has been obtained by noncovalent i... | 149,984 | [
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An analysis of dorsal and median raphe self-stimulation: effects of parachlorophenylalanine. | The role of serotonergic systems in intracranial self-stimulation (ICSS) of the dorsal and median raphe nuclei of rats was investigated. Intragastric administration of 400 mg/kg of parachlorophenylalanine (PCPA) depressed ICSS rates in the group with dorsal raphe electrode placements over a similar time course to the d... | 149,989 | [
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Applications and limitations of quantitative sacroiliac joint scintigraphy. | Evaluation of sacroiliac joint pathology by quantitative analysis of radionuclide bone scanning has been advocated as a useful technique. We have examined this technique in 61 patients and controls. The procedure was useful in detecting early sacroiliitis but was of limited value in patients with advanced sacroiliac jo... | 149,995 | [
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Recent concepts on the pathogenesis of rheumatoid arthritis. | The evidence implicating an immune pathogenesis of the lesions of rheumatoid arthritis is presented under four headings: clinical, histopathological, serological and experimental. This leads to the conclusion that the disease occurs in two phases, an initial phase associated with the presence of an exogenous initiating... | 150,015 | [
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Frequency of Down syndrome in livebirths by single-year maternal age interval: results of a Massachusetts study. | An analysis of rates of intra-state Down syndrome livebirths to Massachusetts residents by single-year maternal age interval in 1958-1965 inclusive was carried out. A gradual increase of rate of the Down syndrome occurred from age 20 to about age 31, and a steeper increase thereafter. Different regression equations wer... | 150,062 | [
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Ultrastructural observations on FUdR-induced cell death and subsequent elimination of cell debris. | Twelve-day mouse embryos were treated with fluorodeoxyuridine (FUdR) and sacrificed at various time intervals after treatment. The neuroepithelial cells were then examined to determine by electron microscopy the primary site of action of the drug. About two hours after treatment mitotic activity ceased and a number of ... | 150,063 | [
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Endocrine cells of the colon in Hirschsprung's and control children. | The large intestine resected from 6 Hirschsprung's patients and surgical colonic biopsies from 6 control children were examined with light and electron microscopy. The presence and the relative distribution of various endocrine cell types in both groups of mucosa were determined. In light microscope studies endocrine c... | 150,104 | [
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Occlusive phlebitis, a diagnostic feature in Riedel's thyroiditis. | Five cases of Riedel's invasive fibrous thyroiditis are presented. Clinically and histopathologically all cases fulfilled the criteria for this lesion. In both small and large veins there were inflammatory changes and obliteration of the lumen, followed by sclerosis. These changes were found in each operative specimen,... | 150,106 | [
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Morphological investigations on axonal swellings and spheroids in various human diseases. | Axonal swellings and spheroids in various human diseases were studied by light and electron microscopy. 4 cases of infantile neuroaxonal dystrophy, 2 of degenerative diseases, 2 brain tumors and 3 of cerebrovascular disease were examined. Ultrastructurally most spheroids in infantile neuroaxonal dystrophy consisted of ... | 150,108 | [
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2'-Chloro-1-hydroxy-2-naphthanilide-4'-isothiocyanate--a new cestodicidal agent [1]. | 2'-Chloro-1-hydroxy-2-naphthanilide-4'-isothiocyanate (4) has been synthesized as the structural analogue of yomesan (1) and was found to be active against experimental dwarf tapeworm Hymenolepis nana infection in rats at an oral dose of 7.5 mg/kg. | 150,149 | [
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Glycoproteins and polyanions in the synapses of rat and mouse central nervous system. | In the present work, it is investigated the location and characteristics of receptors for Con A in synapses of rat and mouse central nervous system. Negatives charges of synaptic surface are also studied. It is observed the presence of glycoproteins on synaptosomal plasma membrane. Presence of negatives charges homogen... | 150,190 | [
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Histochemical fiber composition of lumbar back muscles in the cat. | A histochemical analysis has been performed of the activity of myofibrillar ATPase, NADH2tetrazolium-reductase, succinic dehydrogenase and phosphorylase and of the content of fat and glycogen in the muscles of the cat's lumbar back region. The correlation between the fiber composition and the previously studied contrac... | 150,195 | [
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Anterior pathway for transdiaphragmatic extension of pneumomediastinum. | It is classically taught that mediastinal air enters the abdomen posteriorly by dissection along vascular sheaths. Present studies in infants, children, and young adults demonstrate dissection of extrapleural air to the subdiaphragmatic extraperitoneal space between the sternocostal origins of the diaphragm. The presen... | 150,211 | [
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Multihandicapped children's preferences for pure tones and speech stimuli as a method of assessing auditory capabilities. | Residual hearing capabilities of nine severely and profoundly retarded multihandicapped deaf-blind children were determined with an operant procedure that allowed the children to respond by making a selection between two alternative responses. One response option resulted in the presentation of auditory reinforcement (... | 150,230 | [
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[Epidemiology of contact dermatitis in Marseilles (author's transl)]. | Five hundred subjects were patch-tested on the one hand with 25 allergens standard group and on the other hand with selected allergens depending on the occupation and history of each patient. They systematic standard series are responsible for 79 p. 100 of contact allergens. Among them the most frequent sensitizers obs... | 150,247 | [
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[Immunochemical characterization of alpha-amylases in wheat seeds at different ontogenical steps (author's transl)]. | Protein extracts of wheat seeds taken at an early stage of development, at maturation and after seven days of germination were investigated by using immunochemical techniques with immune sera prepared against alpha-amylases purified from developing seeds and alpha-amylases purified from germinated seeds. After immunoch... | 150,250 | [
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Light chains of chicken embryonic gizzard myosin. | 1. Myosin from gizzards of 15-day-old chicken embryos was highly purified by ammonium sulfate fractionation in the presence of ATP and MgCl2, ultra-centrifugation and Sepharose 4B chromatography. 2. The myosin composed of heavy and three light chains as determined by sodium dodecyl sulfate (SDS) gel electrophoresis. Th... | 150,291 | [
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Delayed-type hypersensitivity in patients with mycosis fungoides. | Cell-mediated immune reactivity was studied in 23 patients with mycosis fungoides and Sézary's syndrome by a semi-quantitative 2,4-dinitrochlorobenzene (DNCB) sensibilization test and the reaction to intracutaneous microbial antigens. Anergy to DNCB was observed in 8 patients, 5 had a markedly depressed DNCB score, 6 s... | 150,343 | [
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[Therapeutic effect and effect on the pituitary adrenal functions of fluocortine-butylester in eczema during childhood (author's transl)]. | A new topical corticosteroid: fluocortin-butylester, was employed in 11 eczematous children (atopic and seborrhoeic dermatitis), with a good clinical result. These topical applications involve no significant risk of interference with the pituitary-adrenal function. | 150,351 | [
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Immune status in Crohn's disease. 2. Originally unimpaired primary cell mediated immunity in vitro. | One-way mixed lymphocyte cultures (MLC) were performed with peripheral blood lymphocytes of 21 patients with Crohn's disease (CD) not receiving salizylazosulphapyridine, steroids or azathioprine, seven patients with inflammatory bowel disease other than CD and ulcerative colitis, and 46 age- and sex-matched normal cont... | 150,362 | [
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0.1609084,
0.05607228,
-0.5120403,
-0.0852014,
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-0.03908837,
-0.2718533,
0.536833,
0.2824593,
0.07204107,
-0.09631282,
... |
Human lymphocyte responses are enhanced by culture at 40 degrees C. | In vitro responses of human peripheral blood lymphocytes (PBL) were found to be markedly enhanced by culture at 40 degrees C rather than at the conventional temperature of 37 degrees C. We studied proliferative responses of lymphocytes by activation by phytohemagglutinin (PHA) concanavalin A (Con A), pokeweed mitogen (... | 150,449 | [
-0.1244086,
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0.4441528,
0.4411843,
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... |
Prophylaxis of the laminectomy membrane. An experimental study in dogs. | Sixty laminectomies were performed in dogs to investigate the prevention of the laminectomy membrane and its side effects. These operations were distributed in six groups of 10, one was a control group, and in the others the bone defect was protected with different materials (Oxicel, Silastic, Dacron, methyl methacryla... | 150,459 | [
0.2674127,
0.07067754,
0.5419734,
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0.20196,
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0.2332966,
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-0.04513361,
-0.05614273,
0.09513263,
-0.01986508,
-0.028088... |
Levamisole: lack of immunopotentiation in a controlled trial. | The immunopotentiating effect of levamisole was assessed in a double-blind trial in two comparable groups of patients with Down's syndrome, with which the immunodeficiency and susceptibility to infection are known to be associated. One group was given levamisole continuously and at the same dose for 16 weeks, and the o... | 150,487 | [
0.04981684,
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0.2377544,
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0.06354191,
0.4802738,
-0.008989449,
0.1606619,
-0.164156... |
Huntington disease: normal lipid composition of purified neuronal perikarya and whole cortex. | This is the first report of the lipid composition of human neurons. Neuronoal perikarya were isolated from frozen samples of the cerebral cortex of persons with Huntington disease and two normal controls. These were analyzed for total lipid, individual lipids, and gangliosides. No differences were detected between dise... | 150,551 | [
-0.0587172,
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0.2279046,
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0.2898794,
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0.5198559,
-0.02916711,... |
[Cholinergizing treatment in hyperkinesis]. | Hyperkineses are a clinical and pathogenetic counter-part of parkinsonism (MP). Their underlying cause is increased activity of the dopaminergic system or insufficiency of the cholinergic system. Treatment inhibiting the dopaminergic system, similarly as anticholinergic treatment is of little effectiveness in MP. A tri... | 150,548 | [
-0.1845731,
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0.2737966,
0.2100027,
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Molecular structure of membrane vesicles from Escherichia coli. | The molecular architecture of membrane vesicles prepared from Escherichia coli ML 308-225 has been studied by using crossed immunoelectrophoresis, and a reference pattern of 52 discrete immunoprecipitates has been established. Progressive immunoadsorption experiments conducted with untreated control vesicles and with p... | 150,599 | [
-0.2531677,
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0.4043851,
0.4898341,
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... |
Effect of Trisetum flavescens P.B. on calcium and phosphorus metabolism in rats. Experimental evidence for the principle actively affecting phospho-calcium homeostasis. | After reviewing the literature on the vitamin D3-like activity of certain plants [Solanum malacoxylon, Cestrum diurnum and Trisetum flavescens], the authors present results of experiments in which dried Trisetum flavescens was administered perorally to rats. The addition of 2.5% dried Trisetum flavescens to the standar... | 150,612 | [
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0.1309216,
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0.09737419,
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0.4552896,
0.08159171,
0.4169412,
-0.1286129,
... |
Effects of pre and perinatal malnutrition on muscle fibres from fast and slow rat muscles. | Pre and perinatal malnutrition of rats was effected by means of limiting the mothers' food intake by 50% during pregnancy and lactation. Male offspring were sacrificed at 36 weeks of age and the anterior tibialis (ANTIB) and soleus (SOL) muscles were prepared for histochemical demonstration of Type I, IIA and IIB muslc... | 150,634 | [
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0.04345122,
0.1410791,
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Transcatheter arterial embolization of a traumatic lumbar artery false aneurysm. | The case of a false aneurysm of a lumbar artery secondary to penetrating trauma is presented. Problems of diagnosis are outlined, emphasizing the value of ultrasound, computerized tomography, and angiography. The early use of angiography is strongly advocated in cases of suspected post-traumatic bleeding. The use and v... | 150,652 | [
-0.0863698,
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0.2465056,
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0.3647654,
0.002340924,
-0.025733... |
Lymphoid cell interactions in allograft immunity. Failure of hamsters to generate suppressor cells upon specific immunization. | The alloantigenic reactivity of hamster spleen cells from unsensitized animals was analyzed in vitro. When compared with normal MHA cells, MHA anti-CB spleen cells responded better or to the same degree in mixed lymphocyte reaction (MLR) during the first 3 days after alloantigenic exposure. However, by day 5 postsensit... | 150,661 | [
0.2280557,
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0.2164388,
0.2164953,
0.1010469,
0.1069229,
-0... |
[Plasmin in human blood plasma]. | Formation of plasmin was studied when treating the human diluted blood plasma with kaolin in acid medium. The activity of the formed enzyme was determined quantitatively from the splitting of protamin sulphate, fibrin and fibrinogen. Dependence of plasminogen activation on time of plasma incubation with kaolin and on t... | 150,669 | [
0.08654835,
0.05665427,
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0.4155473,
0.5510986,
0.09205962,
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... |
[Concentration and composition of cerebral gangliosides in Down's disease]. | Content and composition of gangliosides were studied in brain white and grey substances of patients with mongolism. Content of gangliosides, which are typical components of plasmatic membranes of nervous cells, was decreased in brain grey substance of the patients as compared with control group, whereas content of the ... | 150,702 | [
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0.2258167,
0.02245015,
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0.4323103,
0.423667,
-0.2575823,
... |
[Immunostaging (author's transl)]. | This survey covers the problems of immunologic monitoring of patients and the spectrum of methods of diagnosing various types of immunopathological reactions. | 150,770 | [
-0.03791399,
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0.464334,
0.4471693,
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0.03740411,
... |
[The use of laparoscopy in the diagnosis of ectopic pregnancy and its clinical aspects]. | 11,8% (354 patients) of 3000 laparoscopies were performed because of suspected ectopic pregnancy (E.P.). In 23,4% of the diagnostic laparoscopy the diagnosis was confirmed. The rate of E.P. without bleeding was 11,8%. Laparoscopy is considered to be the method of choice to diagnose as well as to exclude E.P. | 150,771 | [
0.1108801,
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0.2776829,
0.0700805,
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0... |
Importance of bicarbonate in bile salt independent fraction of bile flow. | The bile salt independent fraction (BSIF) of canalicular bile flow from the isolated rat liver perfused with bicarbonate-free perfusate is 50% of that from the liver perfused with bicarbonate-containing perfusate. HCO3-excretion is nearly eliminated and Na+ and Cl- excretion is reduced 50%. Replacement of HCO3- into pe... | 150,796 | [
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0.2555311,
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0.2245407,
-... |
[On the connections between the rami communicantes of the sympathicus and the rami posteriores of the loin nerves (author's transl)]. | The existence of anastomoses between the Rami communicantes of the Truncus sympathicus and the Rami posteriores of the loin nerve in man has been confirmed macroscopically and microscopically in 50% of the cases. This is followed by a discussion of the causality of pains in the loin region. | 150,806 | [
0.2411686,
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0.245783,
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0.03864123,
0... |
Dissociation kinetics of tetra-S-carbamidomethylated plasmin-modified human somatotropin. | The dissociation of tetra-S-carbamidomethylated, plasmin-modified human somatotropin at 25 +/- 2 degrees C has been found to be a slow, exergonic equilibrium reaction; an equilibrium constant of 1.77 mol/L and a standard free energy of dissociation of -340 cal/mol have been calculated. The major products of the dissoci... | 150,855 | [
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0.4160122,
0.1719107,
0.07512133,
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-0... |
Preparation and some properties of homogeneous Neurospora crassa assimilatory NADPH-nitrite reductase. | The Neurospora crassa assimilatory NADPH-nitrite reductase (NAD(P)H: nitrite oxidoreductase, EC 1.6.6.4), which catalyzes the NADPH-dependent formation of ammonia from nitrite, has been purified to homogeneity as judged by polyacrylamide gel electrophoresis. The specific activity of the purified enzyme is 26.9 mumol ni... | 150,863 | [
-0.3374897,
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0.02338208,
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0.307048,
0.2827601,
0.0667003,
0.22... |
[Monoaminergic and peptidergic innervation of rat median eminence, studied by a combination, in the same hypothalamus, of histofluorescent, immunocytochemical and radioautographic technics]. | The application of a combined histofluorescence-immunocytochemical and radioautographic technique on the same rat hypothalamus has revealed : 1) a close correlation between the dopaminergic fibers and LH-RH containing axons all along the external layers of the ME, 2) a probable origin within the periventricular hypotha... | 150,883 | [
0.1261766,
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0.1349382,
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0.02876537,
0.3350055,
0.0007934182,
0.00461615,
... |
[Comparison of the survival of desialylated erythrocytes and demonstration of the presence of T-agglutinin in rabbits and ducks]. | Rabbit as well duck erythrocytes desialization leads to a dramatic decrease of their survival time. Rabbit erythrocytes are trapped transiently by the liver ; in contrast splenic uptake is gradual. Serum from the two species contains a T-agglutinin directed against autologous desialyated erythrocytes. In the two cases,... | 150,911 | [
0.1658916,
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0.2612089,
0.3528378,
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-0... |
[Effects of hypobaric hypoxia and erucic acid on mitochondrial triglycerides in rat heart]. | At normal atmospheric pressure, an erucic acid-supplemented diet produces an increase of heart mitochondrial triglycerides. With the same quantity of erucic acid, hypoxia emphasizes the triglyceride overload in rat heart mitochondria. Thus, hypoxia increases the risk caused by rapeseed-oil. In hypoxia or at normal atmo... | 150,928 | [
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0.07918768,
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0.076966,
... |
Effect of parachlorophenylalanine, a brain serotonin depletor, on the prolactin cells of the eel pituitary. | Parachlorophenylalanine (pCPA), an inhibitor of tryptophan hydroxylase depleting brain serotonin in higher vertebrates, was injected into freshwater eels. After 4 or 8 injections (200 mg/kg/day) or 10 injections (100 and 140 mg/kg/day) plasma electrolyte values were not modified. Prolactin (PRL) cells appear less activ... | 150,951 | [
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0.5077414,
0.01012101,
... |
Role of hyaluronic acid in the in vivo aggregation of cartilage proteoglycans. | From studies of isolated cartilage proteoglycans in solution it has been inferred that they occur in the tissue as aggregates of high molecular weight which consist of proteoglycan monomers, hyaluronic acid and specific link proteins. The present investigation provides direct evidence for the existence of hyaluronic ac... | 150,964 | [
0.07863327,
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0.5831212,
0.1825455,
-0.15496... |
[Phantom experiments and early clinical experience with a mammogram apparatus using a grid (author's transl)]. | The effect of a grid on film quality and dose was investigated in a newly developed mammographic apparatus (Mammo Diagnost U--C. H. F. Müller). It was shown that available film-screen combinations used with a grid produced practically the same picture quality as Definix Medical used without screen or grid. Although the... | 151,055 | [
-0.2743747,
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0.009283616,
0.6488302,
-0.0935158,
-0.05008... |
Grenz rays: adequate or antiquated? | Selected benign dermatoses, recalcitrant to most other forms of therapy, respond to grenz-ray therapy. When appropriately administered, this is a safe treatment for such conditions. This paper delineates the practical application of grenz-ray therapy at the present time. | 151,105 | [
-0.02390025,
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-0.07881914,
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0.214168,
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... |
Aortoarteritis and cardiomyopathy. A heretofore undescribed association. | An interesting association between aortoarteritis syndrome (Takayasu's arteriopathy) and congestive cardiomyopathy has been described for the first time. The severe congestive heart failure in 3 out of 4 cases reported here was not associated with hypertension. Morphologic features of the heart in all cases were charac... | 151,155 | [
-0.1311472,
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0.09939681,
-0.02428797,
-0.223310... |
Some interrelations between the density of the Haversian canals and the area occupied by these in the diaphyseal compact bone in man. | The authors studied the ratio between the density of the Haversian canals and the area occupied by these in the diaphyseal cortex of the main long bones in man. The interrelation was estimated by means of the correlation coefficient, which varies between -0.135 for the fibula and -0.168 for the humerus. It was found th... | 151,216 | [
0.0382654,
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0.1684425,
0.4368645,
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0.03388396,
0.3165724,
-0.02953919,
0.271642... |
Data regarding the structural feature of nervous elements in the bile ducts during intrauterine life. | The nervous elements of the extrahepatic bile ducts were studied on serial sections prepared from rabbit and human embryos and foetuses, using silver impregnation techniques. In the gallbladder of rabbit embryos and foetuses, the nervous elements are absent, whereas the bile ducts possess a dense parasympathetic vegeta... | 151,218 | [
0.02032895,
-0.08872657,
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0.01228427,
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-0.289448,
-0.2077495,
-0.05137153,
0.1661394,
0.1272798,
-0.3392955,
0.03592069,
-0.09755328,
-0.3446541,
-0.106812,
-0.8594655,
0.2645831,
-0.0340523,
-0.01700591,
0.2276862,
0.1666529,
0.0287799... |
Formation dynamics of lymph node metastases after heterografting of Ehrlich ascites tumor cells in rats. | The inoculation of 100 X 10(6) Ehrlich ascites tumor cells into the peritoneal cavity of X-irradiated rats induced a transitory ascites tumor and lymph nodes metastases. The sequential aspects of metastases formation and regression were studied. No metastases were found in non-irradiated rats injected with the same amo... | 151,226 | [
0.1298794,
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0.1096888,
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0.04734562,
0.0401... |
Role of serotonin in feedback control of hypothalamic-pituitary-testicular complex in male rats. | Hemicastration of male rats produced rapid changes in plasma testosterone (T) levels both in summer and in winter. However, in winter, after unilateral castration, the duration of T maximum decrease was found to be longer, but the compensatory increase of blood T following its drop was more dramatic as compared to the ... | 151,240 | [
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0.00607117,
0.1830287,
0.3390822,
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Properties of mitochondrial adenosine triphosphatase isolated from rat liver. | Soluble, oligomysin-insensitive ATPase was isolated from liver mitochondria by a new technique [Drahota and Houstĕk 1977]. Study of the resultant enzyme preparation provided further evidence that the isolated protein displays properties typical of mitochondrial ATPase (specific activity about 100 U/mg, optimum pH 8.2, ... | 151,284 | [
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0.003646369,
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Dopaminergic control of adenohypophyseal growth after oestrogens: negative results with L-DOPA, RO-4-4602, alpha-methyl-DOPA, apomorphine, haloperidol, pyridoxine and cyproheptadine. | Chronic oestrogen treatment augments adenohypophyseal weight and the thyroxine-binding capacity of adenohypophyseal proteins in rats. Since these reactions are both inhibited by ergocornine and ergoline derivatives (as well as by the thyroid hormones, testosterone, anti-oestrogens and antiandrogens), and are potentiati... | 151,287 | [
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A pancreatic-polypeptide-producing tumour associated with the WDHA syndrome. | A case with the clinical appearance of WDHA syndrome is described in which serum concentrations of the newly recognized hormonal principle pancreatic polypeptide (PP) were highly elevated, while plasma levels of vasoactive intestinal peptide were within the normal range. The symptoms of the patient seem to be derived f... | 151,327 | [
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Site of ATPase activity in Myxococcus xanthus: lipid requirement for enzyme activity. Dedicated to Professor Dr. W. Schwartz on his 80th birthday. | Treatment of cells with lysophosphatidylcholine, lysozyme, and phospholipase D removed most of their phospholipids and reduced ATPase activity to near zero. Addition of a microdispersion of phospholipids restored enzyme activity to various degrees. Phosphatidylcholine was most effective in reconstitution experiments, l... | 151,387 | [
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... |
Cell kinetics in the spleen of Ehrlich ascites tumor-bearing mice. | During the period of 18 days after transplantation the uptake of 3H-thymidine into DNA was significantly increased in the spleen of Ehrlich ascites tumor-bearing Swiss and NMRI mice. Adenosine deaminase activity was within the control limits in tumor-bearing Swiss mice and significantly increased for the tumor-bearers ... | 151,393 | [
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0.4543157,
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0... |
Use of the Goal Attainment Scale in the treatment and ongoing evaluation of neurologically handicapped children. | Six children with multiple handicaps were treated as a pilot group by a physical therapist, occupational therapist, and a speech/language pathologist. Baseline evaluations were obtained through a compilation of traditional developmental tests. A Goal Attainment Scale technique was introduced to facilitate reevaluation ... | 151,501 | [
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0.3463662,
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Vectorcardiographic diagnosis of right ventricular hypertrophy in the presence of right bundle branch block in young subjects. | Two groups of young patients, one with right bundle branch block complicated by right ventricular hypertrophy due to congenital heart disease, the other with right bundle branch block and no right ventricular hypertrophy, could be separated on the basis of a few quantitative vectorcardiographic and electrocardiographic... | 151,506 | [
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... |
Rat isolated phrenic nerve-diaphragm preparation for pharmacological study of muscle spindle afferent activity: effect of oxotremorine. | 1. Muscle spindle afferent discharges exhibiting an approximately linear length-frequency relation could be recorded from the phrenic nerve in the isolated phrenic nerve-diaphragm preparation of the rat. 2. Muscle spindle afferent discharges could be identified by their characteristic "spindle pause" during muscle cont... | 151,569 | [
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0.0368062,
0.1855982... |
DNA sequences of promoter regions for the str and spc ribosomal protein operons in E. coli. | The DNA sequences have been determined for promoter regions of two ribosomal protein operons in E. coli, the str operon and the spc operon. The site of in vitro transcription initiation within each of these promoter regions has been determined. The start site of the str operon occurs 69 bases upstream from the initiati... | 151,587 | [
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Bilateral transverse sinus obstruction in benign intracranial hypertension due to hypervitaminosis A. | Hypervitaminosis A may be associated with benign intracranial hypertension. So far, the explanation for this phenomenon has remained obscure. A 17-year-old patient with benign intracranial hypertension, following chronic vitamin A intake of 150,000 units daily for acne vulgaris, is presented. Bilateral papilledema was ... | 151,668 | [
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0.1461398,
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[Orbital sarcoidosis (author's transl)]. | In case of an isolated orbital tumour, which evolves rapidly in a patient, whom general condition is good and who shows no other signs, the possibility of a sarcoidosis must be considered. The diagnosis will be confirmed by a biopsy and often by a tomography of the pulmonary hila, a radiography of the hands and feet as... | 151,707 | [
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0.1817301,
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Hereditary optic atrophy with probable association with a specific HLA haplotype. | A family with hereditary optic atrophy in 4 members of 3 generations is described. The clinical findings differ from those previously observed in hereditary optic atrophy and in Leber's disease, indicating that the hereditary optic atrophy described in this report represents a new disease entity, which is inherited in ... | 151,734 | [
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0.006168775,
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0.1710122,
0.1318202,
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Differential transcription of nonrepeated DNAs in Neurospora crassa mutants. | Transcriptional properties of an "albino" mutant, a "slime" mutant and a wild type strain of Neurospora crassa have been compared by quantitative estimates of DNA:RNA hybridization. The RNAs isolated from these strains were incubated with 32P-DNA of the wild type strain. The DNA:RNA hybrids were isolated by chromatogra... | 151,803 | [
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0.7139163,
0.07164758,
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Relation between the low back pain syndrome and x-ray findings. 2. Transitional vertebra (mainly sacralization). | The relation between LBP and transitional vertebra was investigated in 312 subjects; 148 healthy individuals served as controls. An overall incidence of 0.65% lumbarization and 20.8% sacralization was found; of the latter, one third were partial and two-thirds complete. The incidence was markedly lower in women. No dir... | 151,915 | [
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0.4808542,
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Effect of immunosuppression on the growth of six murine tumors. | Mice have been immunosuppressed with cyclophosphamide, cortisone-acetate, irradiation, or Ehrlich ascitic fluid (EAF) and then grafted with Ehrlich tumor or with one of the following strain-specific tumors: thymoma, methylcholanthrene-induced fibrosarcoma, B-16 melanoma, lymphatic leukaemia, and myeloid leukaemia. Immu... | 151,996 | [
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0.5681656,
0.4806261,
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-0.262... |
Mössbauer spectroscopy on oxygenated sperm whale myoglobin: evidence for an Fe3+-O2- coupling at the active center. | 57Fe Mössbauer spectra of oxygenated sperm whale myoglobin (MbO2) show a well resolved quadrupole doublet with a temperature dependent splitting. The temperature dependence of the corresponding electric field gradient tensor (EFG) can be calculated from a Fe3+ term scheme for the iron at the active center. The Mössbaue... | 152,002 | [
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0.003040576,
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0.1321282,
-0.1187277... |
Conformationally restricted adenine nucleotide analogs in mitochondrial adenine nucleotide transport. | The conformationally restricted adenine nucleotide analogs 8,3'anhydro-8-oxy-9-(beta-D-xylofuranosyl)adenine-5'-O-tri(di)-phosphate (I), and 8,2'-anhydro-8-oxy-9-(beta-D-arabinofuranosyl) adenine-5'-O-tri(di)-phosphate (II), were prepared chemically as their alpha-32P-labelled compounds and compared with syn-structured... | 152,005 | [
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0.1584263,
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-... |
Alterations in ecdysone content during the post-embryonic development of Chironomus thummi: correlations with chromosomal puffing. | The ecdysone titer of larvae and pupae of Chironomus thummi was determined by radioimmune assay (RIA) and revealed a concentration of about 150 ng/g fresh weigth in late third instar larvae and a peak of more than 450 ng/g fresh weight just preceding pupation. The ecdysone titer curve shows a high degree of correlation... | 152,006 | [
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... |
[Effect of meteorologic and heliogeophysical factors on stroke incidence in Leningrad]. | A study of the frequency of strokes in different periodical intervals during 22 years according to the data of Urgent Medical Aid Stations in Leningrad demonstrated a certain influence of environmental physical factors on the incidence rate. Certain intraannual fluctuations with a maximum increase in the winter-spring ... | 152,042 | [
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... |
Phage typing of nontypable isolates of Staphylococcus aureus using the new phages 94, 95, and 96 and the heat-shock treatment. | Of 2,144 isolates of Staphylococcus aureus (from human beings in New York State) received in the authors' laboratory during 1975, 992 (46.,%) were nontypable with the use of the international basic set of bacteriophages. These 2,144 isolates were retested with the use of the recently added phages 94, 95, and 96. Nearly... | 152,059 | [
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0.2304443,
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-0.254711... |
The effect of 5-fluorouracil on abdominal wound healing in rats. | We carried out experiments to test the hypothesis that 5-Fluorouracil would retard wound healing when administration was started on the day of operation. Abdominal wounds were made in rats and closed again, and some of the animals were given daily 5-FU, the rest acting as controls. Test animals were killed three, five,... | 152,105 | [
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-0.2828924,
0.3901028,
0.2406444,
0.1525167,
0.193014... |
Granulomatous and neoplastic diseases of the skin of horses. | Lesions encountered in a clinicopathological study of cutaneous lesions resembling 'swamp cancer' from horses in North Queensland included 37 cases of subcutaneous phycomycosis, 5 of which were also infected with Habronema sp larvae. In addition 9 cases of primary cutaneous habronemiasis, 58 sarcoids, 12 fibromas, 8 fi... | 152,106 | [
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0.4096094,
0.4548292,
-0.2805136,
0... |
Epidermolytic hereditary palmoplantar keratoderma. Report of a family and treatment with an oral aromatic retinoid. | This study describes a family of 30 people in which 14 members have hereditary epidermolytic palmoplantar keratoderma. Four patients were treated with an oral aromatic retinoid for up to 5 months. They responded in a uniform and dramatic way: 10-14 days after the onset of therapy, the hyperkeratotic horny layer was seq... | 152,116 | [
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0.1342484,
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Effects of lanthanum on calcium-dependent phenomena in human red cells. | Lanthanum (0.25 mM) does not penetrate into fresh or Mg2+-depleted cells, whereas it does into ATP-depleted or ATP + 2,3-diphosphoglycerate-depleted cells, into cells containing more than 3 mM calcium, or cells stored for more than 4 weeks in acid/citrate/dextrose solution. In fresh cells loaded with calcium, extracell... | 152,127 | [
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0.1243148,
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0.... |
Laparoscopic assessment of the jaundiced patient: a review of 53 patients. | Laparoscopy in the investigation of patients with jaundice allows visualization of intra-abdominal pathology, target biopsy of intra-abdominal lesions and percutaneous fine-needle cholangiography, all to be carried out at the one procedure. Formal laparotomy can then be planned electively or avoided completely in appro... | 152,136 | [
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0.1049536,
0.03386001,
0.3148314,
0.1049021,
-0.03811183,
-0.09366887,
-0.3446862,
-0.1724007,
-0.5438203,
0.2652888,
0.05438169,
-0.23528,
0.2720702,
0.03039865,
-0.0958031,... |
Chlamydia trachomatis in gonococcal and postgonococcal urethritis. | Chlamydia trachomatis was isolated from the urethra of 38 (28.6%) out of 133 men with gonococcal urethritis (GU). During the follow up of 72 men postgonococcal urethritis (PGU) was diagnosed in 50 (69.5%) patients. More than half (30 out of 50) of these patients with PGU were Chlamydia-positive. Out of 31 patients with... | 152,142 | [
0.1405534,
0.08825348,
-0.3291863,
-0.149863,
0.07806398,
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0.5704345,
-0.3695202,
-0.002527659,
0.266999,
0.03173459,
0.1982799,
0... |
Effect of Sch1000 in allergen-induced asthma. | Carefully controlled allergen inhalation tests were carried out in twelve subjects to provoke early asthmatic responses with a mean maximum FEV1 fall of 30.7 +/- 5.2% (mean +/- s.d.). Four subjects had additional late asthmatic responses with a maximum mean FEV1 fall of 21.0 +/- 5.9%. The tests were repeated at interva... | 152,170 | [
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0.2048437,
-0.1619671,
0.3528018,
-0.2188692,
0.09757619,
0.14395... |
Cell-mediated lympholysis: examination of HLA genetic fine structure and complementation using cytotoxic lymphocytes. | Human cytotoxic lymphocytes (CTL), sensitized in vitro in one-way mixed lymphocyte cultures between two unrelated individuals, have been used to study target cell determinants. One pair of CTL shows strong cell-mediated lympholysis responses against the specific target cells as well as against third-party target cells ... | 152,205 | [
0.01939951,
-0.09667529,
0.1934905,
0.01870084,
0.2220668,
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0.2923474,
0.2842379,
0.1673183,
0.1551126,
0.2073284,
0.002274622,
0.074664,
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-0.1935807,
0.4399278,
0.4358913,
0.3330454,
-0.07272617,
0.153... |
[Intravenous cholegraphy in acute cholecystitis (author's transl)]. | In this prospective study iv-cholegraphy was performed before surgery on 152 patients by whom acute cholecystitis could not be excluded. The examination was diagnostic in 85% of the cases. Most of the patients (20/23) with nonvisualization of the biliary tract by iv-cholegraphy suffered from acute cholecystitis, the ot... | 152,261 | [
-0.0389228,
0.05747958,
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0.0185561,
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0.118243,
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0.3837595,
0.1707356,
-0.0979737,
0.1024616,
-0.0827355,
-0.1031949,
... |
[Post-traumatic findings in the cerebral arteries in the neck (author's transl)]. | Starting from the observation of a post-traumatic thrombosis in the cervical portion of the carotid artery, with two subsequent similar findings, it is shown that angiography is of special importance in assessing these cases. Investigation of the cervical region of this artery should be considered in all cases of skull... | 152,266 | [
-0.03212226,
0.2042032,
-0.0609,
-0.3100751,
0.06811687,
-0.2795486,
-0.3185417,
-0.044998,
-0.0827726,
0.5457925,
0.09492694,
0.08217465,
-0.1528547,
-0.4780964,
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0.07587723,
0.199242,
0.111235,
0.1166799,
-0.1485524,
-0.03897846,
0.3... |
[Haemophilic pseudo-tumours and iliac haematomas: radiological and clinical findings (author's transl)]. | Between 1971 and 1977, 648 patients with haemophilia were seen; of these 38 had pseudo-tumours and 163 iliac haematomas. Amongst the latter 153 were cured by the administration of the appropriate factor. In ten the symptoms persisted. In the early stages the diagnosis cannot be made radiologically. Large haematomas pro... | 152,273 | [
0.0193972,
0.3258703,
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-0.1138024,
0.1837715,
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0.007696281,
0.1652053,
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-0.1435562,
0.0801103,
0.08937288,
-0.02243393,
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-0.07119919,
0.03268329,
0.01467324,
0.349775,
0.214246,
0.06776734,
-0.1874599,
... |
Modulation of immune response by killed Brucella abortus organisms: comparison of the effects of smooth and rough strains on T-dependent responses. | Inactivated Brucella abortus organisms of the smooth (S) or rough (R) strain were tested comparatively on two T-dependent immune responses: mixed-lymphocyte reaction and delayed-type hypersensitivity. The intravenous injection of S organisms depressed the two tests, whereas R organisms increased mixed-lymphocyte reacti... | 152,297 | [
0.01873913,
-0.08803958,
0.05748678,
0.199503,
-0.01256903,
-0.4547745,
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0.2588447,
0.1379569,
0.1675243,
0.2067817,
0.2787577,
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0.40681,
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-0.1668893,
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0.3311882,
0.1767418,
0.1762599,
0.0179496,
-0.0... |
Nuclear division cycle in germinating conidia of Neurospora crassa. | A temperature-sensitive mutant has been shown to be blocked at a specific point in the nuclear division cycle: just before the initiation of DNA synthesis at the time when the spindle pole bodies have duplicated but not separated. The metabolic activities of conidia of this mutant strain at the nonpermissive temperatur... | 152,308 | [
0.01553719,
0.1578727,
0.07025021,
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0.143607,
-0.2069963,
0.1587506,
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0.3915079,
0.02716351,
0.08611581,
0.02079381,
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0.1382376,
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0.0322878,
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-0.263915,
-0.07870978,
-0.01141074,
0.5045339,
0.1944011,
-0.1383171,
0... |
Thymic macrophages modulate one stage of T cell differentiation in vitro. | We have described a procedure for isolating thymic macrophages and have evaluated their activity in stimulating thymocyte maturation in vitro. The culturing of gradient-purified immature thymocytes on thymic macrophages leads to an increased expression of H-2 antigens and decreased lytic sensitivity with anti-TL and C.... | 152,329 | [
0.1012913,
-0.215446,
-0.3135054,
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0.0115937,
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0.1225857,
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0.2310972,
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0.1808897,
0.3221462,
0.08035275,
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-0.0882711,
-0.4075608,
-0.2349178,
-0.1457167,
0.3581379,
0.3605471,
0.02406899,
0.02225224,
0... |
Minocycline-induced loss of potassium from erythrocytes: identification of a family with an augmented response. | The effect of several tetracycline antibiotics of human erythrocytes was examined because of previous findings that these drugs bind to erythrocyte membranes. Minocycline and cetocycline, two highly lipid-soluble analogues, but not tetracycline, induced loss of K+ from red blood cells. Loss of K+ increased linearly wit... | 152,337 | [
0.08731315,
0.1698487,
0.04116455,
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0.256122,
-0.1466892,
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0.08380466,
0.1341578,
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0.1340353,
0.2556199,
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0.5265136,
-0.4074895,
-0.1139688,
-0.5051668,
-0.1156478,
-0.08584587,
0.1212559,
0.4263369,
0.2192405,
0.03064783,
0... |
Lactic acidosis associated with cerebellar vermal atrophy and cardiomyopathy. | The association of fluctuating neurological signs and congestive cardiomyopathy with chronic lactic acidosis is described in a 5 1/2 year-old-boy who ultimately succumbed to congestive heart failure. The autopsy findings included severe atrophy of the anterior cerebellar vermis and a hypertrophied heart with left sid... | 152,418 | [
-0.4810952,
-0.05251949,
-0.06859997,
-0.1881349,
0.007104704,
-0.171456,
-0.08871987,
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-0.1191612,
0.1602862,
-0.08574323,
0.7269975,
0.03009611,
0.01175171,
-0.1269082,
-0.06758828,
-0.3085524,
-0.06548002,
-0.1526787,
-0.02770168,
0.1289234,
0.2930277,
-0.2... |
Functional differences of ouabain and ethacrynic acid on renal potassium metabolism in dogs. | Current concepts provide inadequate explanations for the effects of ethacrynic acid (ECA) and ouabain (OUA) on renal potassium metabolism because neither the site of action, nor the tubular effects have been agrreed upon. In the present study on anaesthetized dogs, in vivo inhibitory effects of ECA on mitochondria or N... | 152,453 | [
-0.228569,
0.1494707,
-0.0731024,
0.2008823,
0.2253725,
-0.3131422,
0.04591081,
0.1468953,
-0.1736877,
0.05288066,
0.001342289,
0.02336714,
0.2998563,
0.05344798,
-1.059186,
0.1016475,
-0.2107605,
0.2301391,
-0.0674648,
-0.078165,
0.3930904,
-0.09378508,
-0.03751869,
-0... |
[Clinical and bacteriological studies with metronidazol in endodontic therapy (author's transl)]. | Metronidazol was employed in the endodontic treatment of 200 gangrenous teeth, with symptoms of acute and chronic periodontitis. In 50 cases aerobic and anaerobic microbiological cultivations have been performed. The number of the necessary treatments was less, symptoms of irritation in the periapical region could not ... | 152,528 | [
-0.0137804,
-0.02151739,
-0.03572506,
0.497824,
-0.1990345,
0.0732341,
-0.3604107,
0.06354887,
0.09766881,
-0.3826795,
-0.2271536,
0.1145839,
-0.1645018,
0.2659962,
-0.562941,
-0.2490525,
-0.2976359,
0.1951834,
-0.2611904,
0.07287222,
0.3377552,
-0.02248552,
0.1152097,
... |
[Evaluation of the clinical effectiveness of paradentosis therapy (author's transl)]. | The x2 test of goodness of fit was used to assess the correlation between empirically determined distributions of a number of characteristics used in parodontology and the model of normal distribution. There was found a more or less pronounced asymmetry in the statistical distributions of some clinical and biochemical ... | 152,529 | [
0.06632432,
-0.03149377,
-0.04751465,
0.1985746,
0.1316638,
-0.3721259,
-0.4852026,
-0.1441864,
0.05430235,
-0.2552252,
0.06926456,
0.1736004,
-0.01850987,
0.3601886,
-0.5460606,
-0.4522322,
-0.04453932,
-0.003343956,
-0.2887382,
0.01964332,
0.2531264,
0.1090766,
0.035887... |
[Objectification of gingival blood-supply disorders by photoelectric plethysmography (author's transl)]. | The measuring method described in this paper is used to photoelectrically detect the volume pulsation of the gingival border. The method, which is remarkable for its ease of application, enables both the original pulse and its first differential derivation to be recorded reliably. Evaluation of the pulse cure is by the... | 152,530 | [
-0.07634958,
-0.1525449,
-0.2666034,
-0.1897554,
0.1850015,
-0.3841377,
-0.3237893,
0.09262472,
0.2274915,
-0.05544523,
-0.1549188,
-0.4025269,
-0.0367284,
-0.05399574,
-0.4581606,
-0.2430309,
-0.2066629,
0.0284686,
-0.03893539,
0.02509014,
0.3728181,
-0.01658419,
-0.0139... |
[Professional allergic diseases in CSSR (author's transl)]. | The authors have watched more than 300 workers of various fodder manufactures in allergological, immunological and clinical way. The findings have been evaluated to the part of the exposition, hygiene and professional allergens. The symptoms of the latent sensitisation so as clinical symptoms after longer time of emplo... | 152,570 | [
-0.09358235,
-0.2367629,
0.1431385,
0.2164145,
-0.09216993,
-0.2130625,
-0.1662638,
0.02905791,
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0.3182711,
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0.1984257,
-0.2473333,
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-0.4230753,
0.06702308,
0.01523133,
0.2161205,
0.009325041,
0.3025706,
-0.2004... |
Speaking fundamental frequency characteristics of institutionalized adults with Down's syndrome. | Mean speaking fundamental frequency was obtained from 16 institutionalized adults with Down's syndrome (8 males, 8 females) and from 16 nonretarded adults of similar age and sex. Both male and female adults with Down's syndrome exhibited a higher mean speaking fundamental frequency than did the nonretarded adults of th... | 152,582 | [
-0.2288748,
0.09043925,
0.1630577,
-0.03453635,
0.05373807,
-0.2034129,
0.04075744,
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0.1574482,
0.1205707,
0.2229925,
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0.06720497,
-0.4272462,
0.2773263,
-0.381179,
0.08024596,
-0.02783057,
-0.2683586,
-0.6038175,
0.08246494,
0.1510561,
-0.2291292,
... |
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