title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Alkaline phosphatase and ATPase activity in the walls of the cerebral vessels in hypertension and arteriosclerosis with disorders of the cerebral circulation]. | In hypertensive disease and atherosclerosis without acute disorders of cerebral circulation it was established that in the cerebral vessel walls there was a high activity of alkaline phosphatase and adenosintriphosphtase. In the symmetrical areas of the subcortical nodes differences in the activity of these enzymes wer... | 146,993 | [
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An electromic differential pressure flowmeter and a resistance meter for continuous measurement of vascular resistance. | An electronic differential pressure flowmeter for mean blood flow measuring and its use in a resistance meter for continuous recording of vascular resistance is described. The flowmeter allows accurate and linear registration also in the small flow range (less than 10 ml/min), thus appropriate for use in small experime... | 147,004 | [
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[Lymphocyte transformation test in the diagnosis of occupational allergy (author's transl)]. | In 139 persons occupationally exposed to compounds of chromium, formaldehyde and p-phenylenediamine lymphocytic transformation test (ltt) was performed to detect a delayed-type hypersensitivity. In patients suffering from either contact dermatitis or allergic respiratory diseases the findings of ltt were concordant onl... | 147,014 | [
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Ouabain binding to phospholipid-dependent adenosine triphosphatase. | The role of phospholipid in the binding of ouabain to the (Na+ + K+)-dependent adenosine triphosphatase was studied. Enzyme preparations obtained from rabbit kidney were treated with Lubrol WX to remove the phospholipid component essential for ATPase activity. Reconstituted enzyme samples were prepared by the addition ... | 147,079 | [
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Acquired platelet dysfunction following mithramycin therapy. | The administration of mithramycin to patients with testicular tumors has been accompanied by a hemorrhagic diasthesis, often in the absence of thrombocytopenia. Bleeding time, platelet aggregation, platelet adenine nucleotide levels, and coagulation factor assays were studied in three patients receiving mithramycin for... | 147,132 | [
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An electron microscopic and enzyme histochemical study of the boundary zone between the white and red pulp of the human spleen. | Three parts were distinguished by electron microscopy and by enzyme histochemistry at the boundary zone between the white and red pulp of the human spleen. The first was the inner layer of the perifollicular region, composed of medium-sized lymphocytes with abundant free ribosomes in their cytoplasm. A small number of ... | 147,141 | [
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Absent tricuspid valve with aortic atresia in mixed levocardia (atria situs solitus, L-loop). A hitherto undescribed entity. | Clinical, angiographic and pathologic features are described in a 36-hour-old male infant with mixed (discordant) levocardia, aortic valve atresia, absent tricuspid (left atrioventricular) valve and resultant massive cardiomegaly. This is the first reported case of this type of complex in a heart with discordant chambe... | 147,146 | [
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Evidence for a correlation between the latency of an early component of auditory evoked potentials and the brain levels of serotonin in albino rats. | Changes in brain serotonin levels are correlated with the latency of an early component of auditory evoked potentials (EAEP) in rats. In fact 5-hidroxytryptophan provokes an increase both in serotonin brain synthesis and in the latency of EAEP. On the other hand, PCPA provokes an opposite effect. | 147,178 | [
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[The radiological diagnosis of peptic ulcer of the oesophagus (author's transl)]. | In the two years 1974--1976, the radiographic diagnosis of peptic ulcer of the oesophagus was made in 14 patients. All these patients showed oesphagogastric reflux at fluoroscopy, 13 had an axial hiatus hernia. The ulcer lay at the oesophagogastric junction in 13 patients, in one patient it was located 5 cm. above the ... | 147,201 | [
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[Preoperative and postoperative stomach evacuation studies via methods of nuclear medicine and methods of roentgen cineradiography (author's transl)]. | A combination of roentgen cineradiography and functional scintigraphy of stomach evacuation, taken with a gamma camera, was used for assessing the success of organ-conservative surgery of ulcers (selective proximal phagotomy with or without pyloroplasty). This confirmed earlier results to the effect that surgical failu... | 147,205 | [
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Pharmacocholangiography. | The effect of ouabain and atropine on bile flow and bile iodine concentration in intravenous cholangiography was investigated in 4 cholecystectomized dogs (20 experiments) with complete bile diversion under general anesthesia and compared to the effect of sodium taurocholate. Iodipamide was administered intravenously w... | 147,207 | [
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[The diagnosis of venous malformation of the orbits (author's transl)]. | The authors describe the frequency, clinical features and methods of diagnosis of venous malformations of the orbits based on their own experience and on the relevant literature. Special attention is paid to plain film diagnosis and angiographic methods of investigation. Orbital phlebography is the most suitable method... | 147,211 | [
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[The use of computers and computer tomography in radiotherapy planning (author's transl)]. | Two examples are used to show how, by means of computer tomography and computers, organ images can be reconstructed; this enhances diagnostic information and helps the clinician in radiotherapy planning. The outlines of tumours or organs which can be obtained serve as the basis for achieving optimal irradiation. | 147,220 | [
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Reexamination of paternal age effect in Down's syndrome. | Paternal age distribution for 1279 cases of Down's syndrome born in 1952--1968 was compared with the corresponding distribution for the general population, corrected for the maternal age as well as for the year of birth of the patients. Although there was no difference in the mean paternal age, the two distributions di... | 147,234 | [
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Post-mortem changes in human central nervous tissue and the effects on quantitation of nucleic acids and enzymes. | A study of post-mortem changes in human central nervous tissue has shown that within 100 h of death, no significant change occurs in the amount of nerve cell DNA and nucleolar RNA nor in some membrane-associated enzymes such as succinate dehydrogenase, NADH and NADPH diaphorase, and cytochrome oxidase. Low molecular we... | 147,255 | [
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Rat locomotory muscle fiber activity during trotting and galloping. | This study was designed to investigate the hypothesis that the trot-gallop transition in running guadrupeds occurs when active cross-sectional areas of muscles or fiber populations within muscles, reach some critical point as animals increase speed within trotting. Rats (Rattus norvegicus) were used as experimental ani... | 147,260 | [
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[Blastogenic response in vitro of lymphocyte acne vulgaris]. | 32 patients with different degrees of acne and 10 healthy controls were studied. On every one of them the test for lymphocytic transformation was performed looking for the range of blastogenic response, using PHA and CA. The positive findings with CA related to those obtained in normal subject would support the hypotes... | 147,371 | [
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[Laparoscopic findings in chronic hepatic porphyria (author's transl)]. | The incidence and significance of gray patches on the hepatic surface found at laparoscopy was investigated in 50 patients with chronic hepatic porphyria. The color change was found in 38 patients; in 28 patients well defined gray dots were found. The incidence is not related to the degree of the metabolic disturbance.... | 147,373 | [
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[Photographic documentation of peritoneoscopic findings with the polaroid camera (author's transl)]. | Photographic documentation of peritoneoscopic findings is technically well developped, relatively easy to perform, and should be used, as a routine procedure. There are different methods available. The polaroid method is the method of choice, when a paper copy with adequate technical quality is needed at once; this is ... | 147,375 | [
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Immunomorphological reactivity of the intrapulmonary lymphoid tissue. | Young albino rats were repeatedly stimulated by a pulverized suspension of living pneumococci and others by intramuscular injection of killed microbes emulsified in complete Freund adjuvant. The bronchus associated lymphoid nodules increase in size and number; the proximal nodules contain one more follicle with germina... | 147,413 | [
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Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. | Previous testing of patients with rheumatoid arthritis showed that one HLA-D type, Dw4, occurred more frequently than in normal controls. B-cell alloantigens closely related to HLA-D can now be identified by a simple serologic procedure. Using this test, I studied 80 white patients with erosive, rheumatoid-factor-posit... | 147,420 | [
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The development of oxidative enzymes in rat liver mitochondria. | During early postnatal development there was an increase in the specific activity of a number of oxidative enzymes localized on the outer and inner mitochondrial membrane. The succinic oxidase complex of the inner mitochondrial membrane, whose activity in 1-day-old rats was 50% of the value in adult animals, attained t... | 147,472 | [
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Effect of amphotericin B on the incorporation of neocarzinostatin into human gastric cancerous tissues. | AmB/NCS combination therapy against cancer was evaluated. Seven gastric cancer and 2 gastric polyp cases were treated in this manner and in addition 2 gastric cancer patients were treated with NCS alone, to serve as the control. AmB dissolved in glucose solution was administered intravenously as was NCS, which was give... | 147,527 | [
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[Fibromatosis of the thyroid gland region. An electron-microscopic and enzyme-histochemical study (author's transl)]. | Two cases of aggressive fibromatosis of the thyroid gland region were studied by histological, immunhistological and electron-microscopic methods. Contractile cells can be found in all tissue preparations using human serum containing antibodies to smooth muscle, especially in the periphery of the tumor. These cells hav... | 147,558 | [
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[Spontaneous transformation in LTT of patients with atopic dermatitis and other allergic skin diseases (author's transl)]. | Increased spontaneous transformation rates have been repeatedly found in the LTT of patients with neurodermits or other diseases. We were interested in the question, if they are to induce artificially. On 37 voluntary persons the LTT was performed before, 24, 48 hours and 1, 2, 3 and 4 weeks after an intracutaneous inj... | 147,613 | [
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MA changes in institutionalized Down's syndrome persons: a semi-longitudinal approach. | A semi-longitudinal approach was employed in this partial replication of a larger study of MA changes in institutionalized retarded persons (Fisher & Zeaman, 1970). Curves were fitted to MA data for a Down's syndrome group and a group of retarded subjects matched on the basis of initial Ma and CA. The findings gene... | 147,627 | [
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[Prolactin and thyrotropin after stimulation by thyrotropin releasing hormone a study under long-term administration of oral contraceptives (author's transl)]. | The longtime application of oral contraceptives is assumed to elevate serum prolactin levels under non-stimulated conditions. We therefore examined whether oral contraceptives also will augment prolactin secretion after stimulation, e.g. by thyrotropin releasing hormone (TRH). After TRH stimulation the time sequence of... | 147,656 | [
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[Aetiological aspects of uveitis (author's transl)]. | An analysis of the probable aetiology of 222 cases of uveitis. In order of frequency the aetiology was: infectious focis 31%, rheumatism 28%, tuberculosis 7.6%, streptococci 4%, viral 3.6%, rickettsia 1.3%, syphilis, brucellosis in 0.5%. In 22.1% of cases the aetiology was not established. In young subjects the majorit... | 147,667 | [
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0.2675387,
0.4206744,
0.2027986,
0.3416365,
0.1694891,
-0.04665503,
... |
Role of negatively charged phospholipids in highly purified (Na+ + K+)-ATPase from rabbit kidney outer medulla studies on (Na+ + K+)-activated ATPase, XXXIX. | 1. The requirement for specific polar head groups of phospholipids for activity of purified (Na+ + K+)ATPase from rabbit kidney outer medulla has been investigated. 2. Comparison of content and composition of phospholipids in microsomes and the purified enzyme indicates that purification leads to an increase in the pho... | 147,706 | [
0.07863007,
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[A preliminary study on parietal stress decay in patients with left ventricular hypertrophy (author's transl)]. | In order to determine equatorial and radial stresses at various depths of left ventricular wall, left ventricular pressures and echocardiographic dimensions were elaborated using the formula proposed by Timoshenko. Patients with concentric left ventricular hypertrophy (LVH) have minor end-diastolic and end-systolic dec... | 147,793 | [
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0.181098,
0.3948211,
0.01698494,
0.04575923,
0... |
[Concentration of antibiotics in long term embolized kidneys (author's transl)]. | In 7 dogs renal arterial embolization was performed using Seldinger technique and inflatable Swan Ganz balloon catheter by injection of methyl methacrylate/butyl 2 cyano acrylat. Six months later tissue concentration of cefazolin was measured in the embolized and kontralateral kidneys and in serum two hours after a sho... | 147,821 | [
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0.2987707,
0.469055,
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0.1104045,
-0.... |
[Disseminated branching pulmonary ossification combined with heterotopic bone formation in the muscles (author's transl)]. | Idiopathic disseminated pulmonary ossification is a rarely recognised condition in which small pieces of marrow containing bone are found in the interstitial tissues of the lungs. The case reported here is unique in showing combination with myositis ossificans circumscripta. The extent of the lung changes was also unus... | 147,825 | [
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0.1841063,
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Rehab Act calls for new approach to interviewing job applicants. | Compliance with regulations implementing section 504 of the Rehabilitation Act will require hospitals to revise hiring practices. Personnel administrators will need to examine employment screening and selection devices, especially, to ensure that they do not discriminate against handicapped applicants. | 147,850 | [
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0.003819816,
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0.1196359,
0.095556... |
The use of the low back and the dorsal scales in the identification of functional low back patients. | Scores from the Low Back (Lb) and the Dorsal (DOR) scales of 20 patients with functional low back pain, 20 patients with functional gastrointestinal pain, and 20 psychoneurotic patients were compared. Among the various proposed cut-off scores, the Lb score of 11 yielded the highest rate (75%) of correct identification ... | 147,886 | [
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0.2521932,
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0.4039621,
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Personality characteristics of physically impaired adolescents. | Investigated MMPI profile differences between disabled and nondisabled (normals). Comparison of mean raw scores on the MMPI was made by t-tests. A preliminary analysis that compared adolescents with congenital versus traumatic impairment yielded only one significant finding: Scale O (Si) (p is less than .05) for female... | 147,887 | [
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0.2618392,
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0.2098858,
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... |
Isolation and characterization of naturally occurring subclasses of human peripheral blood T cells with regulatory functions. | By utilizing naturally occurring autoimmune antibodies from patients with juvenile rheumatoid arthritis, we have isolated and functionally characterized two unique subpopulations of T cells. JRA+ T cells, i.e., those identified by sera from these patients, react poorly in response to allogeneic cells, respond to Con A ... | 147,907 | [
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0.3535252,
0.03894943,
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... |
[2 new species of nematodes of the family Dolichodoridae (Nematoda: Tylenchida) from the soil around cotton roots]. | The description and figures of two new species of nematodes of the genus Tylenchorhynchus Cobb, 1913 are given. T. variannus sp. n. is characterized by an asymmetrical position and variation of the width of cuticular rings in the trophic, genital and caudal parts of the body. It differs from T. irregularis Wu, 1969 in ... | 148,023 | [
0.127366,
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0.1943391,
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0.08072746,
0.3507341,
0.6827213,
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... |
Long systems of the dorsolateral fascicle: influence of afferentation from the splanchnic region. | The influence of afferentation from the splanchnic region on the activity of long systems in the dorsolateral fascicle (DLF) was studied in chloralose-anaesthetized cats. Ascending axons (the dorsal spinocerebellar tract, DSCT and the spinocervical tract, SCT) did not respond to splanchnic stimuli. Conditioning from th... | 148,056 | [
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0.2041388,
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Radioimmunoassay of an early plasmin degradation product of human fibrinogen, "fragment A", and its clinical application. | Upon the plasmin digestion of human fibrinogen, an early cleavage product, which has been designated as fragment A, was isolated, and to study the action of plasmin in the circulation, radioimmunoassay for fragment A was carried out. This assay used rabbit immune serum obtained by injection of fragment A mixed with com... | 148,116 | [
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0.7656521,
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Exercise testing for detection of myocardial ischemia in patients with abnormal electrocardiograms at rest. | This review consists of two parts: (1) discussion of the electrophysiologic mechanisms that are believed to produce ventricular repolarization changes during the electrocardiographic stress test, and (2) clinical assessment of the electrocardiographic changes with stress in patients with an abnormal electrocardiogram a... | 148,209 | [
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Severe mitral regurgitation with a normal-sized left atrium. | The syndrome of severe mitral regurgitation with a normal-sized left atrium may or may not be associated with pulmonary hypertension and prominent left atrial V waves. To explain these pressure alterations by a single pressure-volume relationship is probably not adequate. It would appear that, whatever the clinical cir... | 148,228 | [
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... |
Menstrual patterns after laparoscopic sterilization using a spring-loaded clip. | Details of the menstrual cycles in 504 women were recorded before laparoscopic sterilization with a spring-loaded clip and at six months and one year after the procedure. The operation did not affect the length of the menstrual cycle or duration of menstrual flow, nor the patient's assessment of the amount of blood los... | 148,290 | [
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0.1501468,
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Study of a kindred with partial deficiency of red cell 2,3-diphosphoglycerate mutase (2,3-DPGM) and compensated hemolysis. | A kindred with partial deficiency of red cell 2,3-diphosphoglycerate mutase (2,3-DPGM) was studied. The propositus presented with indirect hyperbilirubinemia, normal hemoglobin (15.8 g/dl), and elevated reticulocyte count (4.6%). The red cell 51Cr survival was decreased (tau1/2 16 days). Incubated osmotic fragility was... | 148,301 | [
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0.5351311,
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... |
Regional brain atrophy and reductions in glutamate release and uptake after intrastriatal kainic acid. | 1 Neurochemical changes and tissue weights were measured following intrastriatal injection of 2.5 microgram of kainic acid in 2 microliter of 0.9% w/v NaCl solution (saline) in the rat. 2 After kainic acid the striatum and neocortex on the injected side showed a progressive reduction in weight, the neocortex showing th... | 148,306 | [
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Ultrastructural, cyto- and biochemical observations during turnover of plasma membrane in duck salt gland. | The mechanism of plasma membrane turnover was investigated using the duckling salt gland as a model system. Feeding fresh water to salt-stressed ducklings results in a decrease in the Na, K-ATPase in salt gland to non-stressed levels in about 7 days, as measured by ATP hydrolysis and 3H-ouabain binding. Electron microg... | 148,323 | [
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0.4641459,
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Influence of endotoxin on myocardial calcium transport and the effect of augmented venous return. | The influence of endotoxin shock and of experimentally increased venous return during endotoxin shock on myocardial vesicular calcium uptake and calcium stimulated ATPase activity was investigated. Vesicular calcium uptake was depressed (p less than 0.01) from 0.9 mumoles/mg protein/min to 0.3 mumoles/mg/min after 5 hr... | 148,334 | [
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0.2991772,
0.1684204,
0.3067565,
0.2215824,
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0.230... |
Effects of macromolecular compounds on human leukocyte beta-galactosidase activity. | The enzyme properties of leukocyte beta-galactosidase and the effects of macromolecular compounds on its activity were studied in detail. It was demonstrated that various macromolecular compounds markedly influence the activity of beta-galactosidase. These phenomena should be taken into account when considering the bio... | 148,337 | [
0.05895404,
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Phase I studies on chlorozotocin. | A phase I investigation of chlorozotocin, a new-water soluble chloroethylnitrosourea, was undertaken to define its pharmacologic effects in man. Forty-three patients received single intravenous doses ranging from 5 to 175 mg/m2 every 6 wk. No signs of toxicity were observed at doses of under 120 mg/m2, but thrombocytop... | 148,344 | [
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0.3146202,
0.2082814,
0.2315072,
0.1017537,
0... |
Studies of the hemopoietic microenvironments: effects of acid mucopolysaccharides and dextran sulphate on erythroid and granuloid differentiation in vitro. | The effects of acid mucopolysaccharides (AMPS) on in vitro erythrocytic and granulocytic colony formation of murine bone marrow cells have been studied. High concentrations of chondroitin sulphate A, B and C and heparitin sulphate partly or completely inhibited the response of CFU-E to erythropoietin stimulation wherea... | 148,364 | [
0.1422696,
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0.3439891,
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0.3372197,
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0.2548273,
0.249466,
0.01630964,
0.1788521,
-... |
[Experience with the tupla-clip for tubal sterilization by laparoscopy (author's transl)]. | For the last 18 months a plastic clip made of polyoxymethylene was used for tubal sterilization by laparoscopy. The clip was used in 140 cases. This report reviews 106 cases. One pregnancy occurred early in this series. There were no other complications. The advantages of the method are the short operating time and the... | 148,388 | [
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0.05693234,
0.05807595,
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0.0977513,
0.03632991,
0.3388095,
0.335712,
-0.2984138,
... |
[The diagnostic value of kymography in aortic isthmus stenosis (author's transl)]. | The value of kymography was studied in 133 patients in whom a coarctation had been demonstrated angiographically, operatively or pathologically; its value was compared with conventional radiographic examinations. The difference in pulsation between the pib notching, dilatation of the ascending aorta and increased size ... | 148,398 | [
-0.1361712,
0.3139758,
-0.2026779,
-0.2991293,
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0.09628434,
0.2554481,
0.2743765,
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-0.3388033,
0.2336098,
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-0.07656483,
0.6284345,
0.03261157,
0.1102762... |
[Neurophysiological activation and behavior during mental achievement. Comparative studies in healthy, minimally brain damage and mongoloid children]. | A comparison of normal, mildly brain-injuried and mongoloid children. For psychophysiological investigations in young or mentally disturbed children a new methodical approach was developped. In children with minor nervous dysfunction (aged 6--8;3 years) and mongoloid children (5;6--11 years) as well as in younger and ... | 148,423 | [
-0.003805218,
0.09038946,
-0.2308219,
-0.2632504,
0.212959,
-0.1872504,
-0.6648302,
0.0716127,
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0.1341942,
0.2320087,
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-0.1246087,
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0.1129323,
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0.06165799,
-0.2857017,
0.2483466,
0.307928,
0.08585678,
-0.08597366... |
Carbonic anhydrase (acetazolamide-sensitive esterase) activity in the blood, gill and kidney of the thermally acclimated rainbow trout, Salmo gairdneri. | 1. Gill, kidney and blood levels of acetazolamide-sensitive esterase (carbonic anhydrase) activity were estimated at acclimation temperature and at a common temperature (25 degrees C) in rainbow trout acclimated to 2, 10 and 18 degrees C. Plasma levels of sodium, potassium and chloride were also examined for possible a... | 148,485 | [
-0.149613,
-0.1672515,
-0.3861823,
0.06401735,
-0.2443669,
-0.1415399,
-0.349169,
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0.001816112,
0.1681555,
0.3650514,
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0.3456304,
0.1035707,
0.150173,
-0.01575145,
0.2591154,
-0.1161386,
0.... |
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation. | The effect of a new chemical agent, SG 75, on coronary blood flow of anesthetized dogs has been examined. Intravenous administrations of this agent in a dose of 10 microgram/Kg or over caused a significant increase in blood flow of non-constricted coronary artery. Percent increases in flow were 40 (10 microgram/Kg), 95... | 148,520 | [
-0.2981318,
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0.0723594,
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0.1256891,
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0.03498783,
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0.1037105,
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0.157867,
0.3714133,
0.01749496,
0.2669013,
-0.04620574,
... |
Stimulation of rat prolactin secretion by indolealkylamine hallucinogens. | The hallucinogenic indoleamine drugs N,N-dimethyltryptamine (N,N-DMT), psilocybin, bufotenin, 5-methoxy-N,N-dimethyltryptamine, and N-methyltryptamine, increased rat plasma prolactin (PRL) levels. The increase in plasma PRL produced by N,N-DMT, psilocybin, and bufotenin was inhibited by methysergide, a serotonin recept... | 148,665 | [
-0.2415728,
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0.06084736,
0.03050903,
0.1012528,
-0.172947... |
[Fatigue fractures: apropos of 8 cases]. | Eight cases of fatigue fracture were observed by the authors. In two patients, they presented in metatarsal bones; others were in the lower end of the tibia, in the shaft of the fibula, in the patella, at the upper end of the fibula, in the shaft to the tibia and in the neck of the femur. The main features of these fra... | 148,704 | [
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0.04665271,
0.4042634,
0.1823361,
0.07882876,
-0.24572... |
Identification of soluble fibrinogen fibrin monomer complexes by non-enzymatic polymerisation in the tissue. | In states of plasmic hypercoagulability and consumption coagulopathy ethanol favours the non-enzymatic polymerization of circulating soluble fibrinogen fibrin monomer complexes (FFMC) in vitro. The ethanol-gelation test of Godal and Abildgaard makes use of this phenomenon, called paracoagulation. The present studies sh... | 148,778 | [
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0.09592175,
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0.0562476,
0.1671836,
0.09279343,
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... |
Significance of a terminal R wave in lead V1 of the electrocardiogram. | A terminal r wave in Lead V1 lower than 0.6 mV. was studied in the ECGs of four groups: (1) 104 healthy children, (2) 207 healthy young adults, (3) 171 patients with no autopsy evidence of a cardiopulmonary disease, and (4) 1,078 autopsy patients with a cardiopulmonary disease. Cases with a complete right bundle branch... | 148,838 | [
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0.04421598,
0.6624806,
0.2412803,
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... |
Hereditary atrial septal defect. Update of a large kindred. | A large pedigree wherein members are predisposed to atrial septal defect (ASD) and associated cardiovascular anomalies has been studied. There were ten direct line relatives with ASD verified by cardiac catheterization and/or surgery and in one case by reliable medical history. The pedigree shows vertical transmission ... | 148,839 | [
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0.4943077,
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0.1121128,
0.1721572,
0.02860642... |
Pulmonary vascular changes in scleroderma. | To determine the incidence and significance of pulmonary vascular changes in scleroderma, all necropsy reports of patients with scleroderma who died at the Massachusetts General Hospital were analyzed and correlated with clinical data. The records of 30 such patients were available. Fourteen had moderate or marked abno... | 148,843 | [
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... |
On data and methods in investigations on parental-age effects. Comments on a paper by J. D. Erickson. | An analysis of the NIS data used by Erickson (1977) has revealed that this data contains too few Down's syndrome cases with older fathers. Thus the data is less suited for an investigation of a possible paternal age effect. In addition, the statistical tests used by Erickson have low power, so that they are unable to d... | 148,867 | [
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0.3592602,
0.1359279,
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-0.0... |
[The dependence of the effects of calcium ions on enzymatic hydrolysis of phospholipids on the physical state of the substrate]. | The role of calcium ions in the phospholipid hydrolysis by phospholipase D was studied. It was shown that the enzyme does not split egg lecithine in the absence of Ca2+. In the presence of Ca2+ the reaction occurs via different routes, depending on the type of initiation of the reaction. The optimal concentrations of C... | 148,917 | [
-0.1033052,
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0.3754699,
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0.357222,
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... |
[Isolation and properties of CF1 ATPase chloroplasts with changed submolecular structure]. | An isolation procedure is worked out and properties are studied of CF1 ATPase from chloroplasts with changed submolecular structure. The enzyme, isolated by chlorophorm treatment, produced Ca-dependent ATPase activity in water solution. As compared with the enzyme isolated by well known Lien and Racker method, the enzy... | 148,926 | [
-0.1757173,
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0.6036425,
0.1682262,
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0.2... |
[Reticular activation by splanchnic afferents: its influence on visual projections at the level of the cerebral cortex in cats]. | In an previous work, we have shown a strong increase of visual evoked potentials of the medial lateral gyrus by splanchnic stimulation. This present study demonstrates that this effect is due to the activation of the substantia reticularis. Actually, we observed: 1) an increase of the reticular visual potential by spla... | 148,947 | [
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0.0936738,
0.157432,
0.08183809,
0.1926588,
-0... |
[Histochemical study of the subcommissural organ in chickens during development]. | Some histochemical and particularly histoenzymological tests are performed on the subcommissural organ of chick embryos. A secretory activity appears about the 7th day. In 10 days old embryos and new hatched chicken the enzyme activities are of rather low intensity. Compared with the 10 days embryos, the newborn show s... | 148,962 | [
-0.01882216,
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0.1026136,
0.05454121,
0.3295918,
0.5029372,
-0.007976263,
0.0707129... |
[Influence of horizontal immersion on urinary excretion of catecholamines]. | Normal man submitted to thermoneutral water immersion in horizontal position presents an increase in diuresis, natriuresis and creatininuria. Noradrenalinuria and adrenalinuria are reduced, indicating a decrease in orthosympathetic activity. | 148,963 | [
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0.07415125,
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0.05533043,
0.01907051,
... |
Effect of actinomycin D and neoarsphenamine on tumor control and skin tolerance in the rat. | Actinomycin D and neoarsphenamine were tested for their ability to produce therapeutically favorable radiosensitization in the WAG/Rij rat. Acute and late skin reactions and control of the BA1112 rhabdomyosarcoma were examined in drug-treated and untreated animals irradiated in single- and five-fraction schedules. Acti... | 148,967 | [
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0.1002119,
0.5431083,
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... |
Regulation of the mixed leukocyte culture reaction by suppressor cells. | Regulation of the mixed leukocyte culture (MLC) reaction by suppressor cells raised and tested in MLC has been evaluated. The experiments described suggest that suppressors are distinct from cytotoxic T lymphocytes (CTL), both in terms of conditions optimal for their activation, as well as through demonstration of effi... | 149,009 | [
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0.02646215,
0.4787248,
0.4357685,
0.07230846,
0.01240... |
[Two cases of infantile cortical hyperostosis (monostotic form) (author's transl)]. | Two cases of infantile cortical hyperostosis, both of the monostotic form, are described. In the first patient the right clavicle was involved; the disease may have been present from birth, but resulted in the infant's admission at the age of six weeks. The second patient was a 7-month old infant who developed the dise... | 149,059 | [
-0.2522036,
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0.07363979,
0.5397145,
-0.05841981,
-0.093081... |
[Specific oesophagitis (author's transl)]. | Tuberculous oesophagitis is a very rare finding; of all organs, involvement of the oesophagus is the least likely. Autopsies on tuberculous patients show an incidence of 0.14%. According to Wexels, only 125 cases have been described in the world literature up to 1954. In general, tuberculous oesophagitis can be include... | 149,065 | [
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0.07502461,
0.08039888,
0.2287904,
0.1880299,
-0.0826027... |
[Radiologic visualization of the normal duodenal minor papilla (author's transl)]. | The anatomical knowledge that the normal duodenal minor papilla is a rather flat protrusion situated on the anterior wall of the descending duodenum, means that double contrast hypotonic duodenography in the Prone position is the method of choice to visualize it. By using this technique the normal duodenal minor papill... | 149,067 | [
-0.1202818,
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0.247657,
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-0.1672931,
0.2074515,
-0.02004046,
-0.03246295... |
Cell-mediated immunity in measles using the leucocyte migration test. | The cell-mediated immune response was investigated in 21 children with acute measles and in 8 healthy children using the intradermal Heaf and leucocyte migration tests. Tuberculin and purified protein derivative were used as antigens. Whereas all the children with measles were anergic in the in vivo test, two groups of... | 149,090 | [
-0.3861459,
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0.3574052,
-0.210168,
0.1967826,
-... |
Carbodiimide-resistant mutant of Escherichia coli: suppression of resistance to dicyclohexylcarbodiimide by growth on glucose or glycerol. | We have previously reported on the isolation of a mutant strain of Escherichia coli, RF-7, that has a dicyclohexylcarbodiimide (DCCD)-resistant, membrane-associated adenosine triphosphatase (ATPase) activity (R. H. Fillingame, J. Bacteriol. 124:870--883, 1975). We report here that the DCCD resistance of the ATPase of t... | 149,107 | [
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0.2025114,
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0.1612009,
0.09875414,
-0.0771971,
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-... |
Does cycloheximide-induced loss of phosphate uptake activity in Neurospora crassa reflect rapid turnover? | Addition of cycloheximide to Neurospora crassa germlings growing in liquid medium caused an exponential loss of phosphate uptake activity (half-life, ca. 2 h). No loss of activity resulted when germlings were resuspended, at the time of cycloheximide addition, in medium of a substantially lower phosphate concentration.... | 149,111 | [
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0.4505912,
0.1549135,
0.07425... |
Effects of tryptic digestion on the enzymatic activites of chicken gizzard myosin. | Tryptic digestion of gizzard myosin resulted in the degradation of the 20K light chain (G1) to its 17K fragment, which could not be phosphorylated. The rapid loss of Ca2+-dependent activation of actomyosin ATPase activity accompanied the degradation of G1. Increase in the Ca2+-ATPase activity and decrease in the EDTA-A... | 149,123 | [
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0.45214,
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0... |
Myosin-like protein and actin-like protein from Escherichia coli K12 C600. | Myosin-like protein was obtained from E. coli by extraction with a sucrose solution and by precipitation with rabbit skeletal actin. The preparation of E. coli myosin-like protein looked very similar, in the sodium dodecyl sulfate-gel electrophoretic pattern, to that of rabbit skeletal myosin. The myosin-like protein w... | 149,124 | [
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0... |
Purification of the Ca2+-stimulated ATPase activator from human erythrocytes. Its membership in the class of Ca2+-binding modulator proteins. | The activator of the Ca2+-stimulated ATPase of erythrocyte membranes was purified 13,000-fold to homogeneity from human erythrocytes. The protein gave a single band upon electrophoresis both with and without detergent, and upon isoelectric focusing. This protein was compared with Ca2+-binding modulator proteins from bo... | 149,133 | [
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0.3069927,
-0.005394731,
... |
Characterization of a second myosin from Acanthamoeba castellanii. | We purified a 400,000 molecular weight myosin, myosin-II, from Acanthamoeba castellanii. The sequence of ion exchange chromatography, actomyosin precipitation, actin extraction, and gel permeation chromatography yields per 100 g of cells about 11 mg of myosin-II which is 90 to 96% pure. ATPase activity is highest in th... | 149,136 | [
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0.765024,
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... |
Teaching self-hypnosis to patients with chronic pain. | For the past twenty years hypnotherapy and self-hypnosis have been utilized as valid tools for the successful management of severe protracted pain. Control often has been achieved in cases where other modalities of pain management had been inadequate. Hypnosis properly applied can bring some degree of improvement to 90... | 149,170 | [
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0.1364074,
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0.02048491,
-0.03360884,
-0.3... |
Observations on the infectivity of parasitic third-stage larvae of Uncinaria lucasi Stiles 1901 (Nematoda: Ancylostomatidae) of Northern fur seals, Callorhinus ursinus Linn., on St. Paul Island, Alaska. | Twelve fur seal pups, which had not nursed their mothers, were used in an infectivity experiment. Pups were exposed to parasitic 3rd-stage larvae of Uncinaria lucasi from belly tissues of fur seal bulls, bachelors, and pregnant cows, to determine maturation capability of the larvae. Hookworms were not recovered from th... | 149,188 | [
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0.2892761,
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... |
The influence of etiology on the surgical management and prognosis of the massively dilated ureter in children. | The massively dilated ureter is a major therapeutic challenge that faces the pediatric urologist. In those instances when more conservative measures, such as control of infection or correction of the primary pathology, have failed or are likely to fail surgical treatment must be directed to the massively dilated ureter... | 149,204 | [
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0.447823,
0.2353316,
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... |
Evaluation of a mental health educational project in Burma. | In attempting to evaluate a brief course on care of the mentally ill given to health personnel in Burma, experience suggested: (a) that post-course questionnaires asking participants to rate usefulness of the educational experience are useless in evaluation; (b) Assessments of clinical knowledge before and after the co... | 149,225 | [
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0.588515,
0.1186268,
0.2148605,
-0.0145... |
Soft tissue xeroradiography. | Xeroradiography of soft tissue lesions, both malignant and benign, has been performed on 121 patients, 79 of whom having also undergone conventional film radiography. In 72 cases (59%), the diagnosis was proved by surgery and histological examination. Xeroradiography was found to be more effective in representing soft ... | 149,335 | [
-0.001135353,
0.027502,
0.06566359,
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0.01397129,
-0.2010994,
-0.1002377,
-0.161714,
0.2232344,
0.2480711,
0.1406092,
-0.05154947,
-0.158034,
-0.04165563,
-0.4410791,
-0.2532202,
0.163868,
0.09325752,
-0.004129708,
0.03252267,
0.4700033,
0.2505406,
-0.1708582,
... |
Effect of in vivo exposure to allogeneic cells upon subsequent in vitro T cell responses and upon allograft rejection. | The effect of intravenous injection of 10(6) BALB/c spleen cells into C57B1/6J recipients was assayed by both mixed lymphocyte culture (MLC) of recipient lymphocytes, and by grafting donor (BALB/c) thyroids into recipient mice. It was observed that a single intravenous injection produced depression of proliferative and... | 149,361 | [
0.01540754,
-0.5095064,
-0.3889185,
-0.3071378,
0.05480665,
-0.1166177,
-0.08148824,
0.2550878,
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0.1645332,
-0.1634752,
0.5603431,
-0.01712639,
0.04858351,
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0.006712717,
-0.05139142,
-0.0661663,
0.1335127,
0.4042438,
0.4013658,
0.4078857,
0.04026975,... |
Anomalous origin of the right pulmonary artery from the ascending aorta associated with aortopulmonary window. | A rare case of anomalous origin of the right pulmonary artery from the ascending aorta associated with an aortopulmonary window and severe pulmonary hypertension in a 13-year-old girl is reported. The window was closed using a Dacron patch and the continuity between the anomalous vessel and the main pulmonary artery wa... | 149,391 | [
-0.168811,
-0.1645914,
-0.3951007,
0.2198876,
0.07948814,
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0.01126633,
0.1911791,
0.2900763,
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0.05227277,
-0.1243019,
-0.3390163,
0.1203502,
-0.1081304,
-0.2993837,
0.3156415,
0.006296256,
-0.01828017... |
Long-term ureteral replacement prosthesis. | A silicone rubber tube with bonded Dacron felt cuffs have been implanted in dogs as a ureteral replacement prosthesis. A one-way valve has also been developed to prevent reflux so the prosthesis may be put into the bladder. The prosthesis has been implanted for periods up to nine months. Although there are some problem... | 149,409 | [
-0.207606,
0.2089744,
-0.0861017,
-0.05660567,
-0.06438459,
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-0.09495446,
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0.05666702,
0.2305239,
0.4206104,
0.2004877,
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-0.08879692,
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0.09614968,
-0.1776082,
0.1459923,
0.04565603,
-0.2908909,
0.09649321,
0.02342898,
0.0831495... |
Cytomegalic adrenal hypoplasia with pituitary cytomegaly. | A case of cytomegalic congenital adrenal hypoplasia (C.C.A.H.) is reported with similar cytomegalic changes in the hypophysis. In this case the pituitary gland was small as were the thyroid and testes. The various groups of patients with C.A.H. are presented. Associated pituitary cytomegaly does not appear to have been... | 149,412 | [
-0.2285424,
0.00653718,
-0.1907124,
0.05140399,
0.04769738,
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-0.5330678,
0.1086766,
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0.2299588,
0.3995779,
0.4986168,
0.004158726,
0.04737623,
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0.1082857,
-0.2495521,
0.3528172,
0.1220715,
-0.1260138,... |
[Endoscopic studies in determining the stage of lung cancer]. | An associated simultaneous mediastino- and laparoscopy allows the detection of lung cancer metastases in lymph nodes of the anterior mediastinum and liver and thereby the precise determination of the tumor process stage. The procedure is tolerated by patients well. 100 examinations showed metastases in mediastinal lymp... | 149,431 | [
0.1146463,
-0.1403301,
-0.2444697,
-0.2661022,
0.07610721,
-0.3160354,
-0.4745309,
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0.3042622,
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0.1521012,
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0.04445262,
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0.3463943,
0.2662661,
-0.06033992,
0.53106,
0.1349532,
0.04187162,
... |
[Investigation of crystalline structures in fats of animals by x-ray scattering (author's transl)]. | Fat-praeparates of cow and pork have been investigated by small-angle X-ray scattering methods. Dependent on the temperature these fats show distinct X-ray interference patterns in the small-angle region. Hence complete phasediagrams of the fats in the temperature region between -20 degrees C and 55 degrees C could be ... | 149,450 | [
0.1674008,
0.049221,
-0.07260418,
0.3615865,
0.02888071,
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0.001313983,
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0.1041567,
0.07257918,
-0.4440113,
-0.1267472,
0.2629239,
-0.7039828,
-0.2027272,
-0.297863,
0.1786108,
-0.06876004,
0.5254918,
0.4933749,
0.2979443,
-0.1237603,
... |
Adverse reactions with methyldopa--a decade's reports. | During 1966-75 the Swedish Adverse Drug Reaction Committee received some 300 reports of reactions to methyldopa. As the Swedish rules for reporting adverse reactions emphasize the importance of severe and unexpected reactions, the relative incidence of various adverse effects differs greatly from what would be found in... | 149,490 | [
-0.2524828,
-0.07959089,
-0.1750485,
-0.09507155,
0.1783667,
-0.2031445,
0.101675,
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0.04842075,
-0.133886,
0.2569305,
0.140917,
0.1575733,
0.005635352,
-0.17383,
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-0.2416236,
0.3915199,
0.3644078,
0.2772912,
0.2984939,
0.1593137,
-0.1929004,
-0.115... |
ECG aberrations, latent coronary heart disease and cardiopulmonary fitness in various age groups of Norwegian cross-country skiers. | To assess the prevalence of possible, latent coronary heart disease (CHD) among physically active men, 149 elite cross-country skiers in three age groups (26-33, 43-50 and 58-64 years) were invited for an examination which included clinical examination, Vitalogram, resting ECG, and a near maximal bicycle test. Of the i... | 149,491 | [
-0.2118036,
0.331753,
-0.1327162,
-0.3294858,
-0.3047373,
-0.180491,
-0.1284443,
-0.4404873,
-0.1681051,
-0.172014,
0.1765162,
0.4540265,
-0.2102484,
0.1840488,
-0.1643359,
-0.2154488,
-0.3999169,
0.4906278,
0.2429234,
0.1269146,
0.1947089,
0.4421503,
-0.06868244,
-0.13... |
Psychological adjustment to physical disability: trends in theories. | Explanations of psychological reactions to physical disability have recently tended to ascribe maladjustment to environmental rather than to personal causes. Historically, common-sense theories were first replaced by metalistic doctrines. These, in turn, were later supplemented by theories that integrated mentalism wit... | 149,525 | [
-0.5099843,
-0.2421763,
0.2254042,
0.2147763,
0.15261,
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-0.07708382,
0.274801,
0.2136987,
0.1127288,
0.08554614,
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-0.05305119,
-0.3251413,
0.07728796,
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-0.2424067,
0.0374735,
-0.2796512,
-0.1594559,
-0.3879703,
0.2581024,
-0.2000715,
... |
[Effect of blockers of serotonin and noradrenaline synthesis on learning with emotionally different reinforcement in rats]. | The effect of inhibitor of serotonin and norepinephrine synthesis in the brain on learning was investigated in rats with emotionally different reinforcement. Parachlorphenylalanine (320 mg/kg) was shown to inhibit learning with food reinforcement, but facilitated learning with pain reinforcement. Disulfiram (100 mg/kg)... | 149,574 | [
-0.1750833,
-0.04474583,
-0.2425539,
-0.2203804,
-0.08111074,
-0.314308,
0.05470358,
-0.1466827,
-0.2305405,
-0.1898063,
-0.06998262,
0.5536573,
0.3277908,
-0.1971484,
-0.6703829,
-0.1420534,
-0.2149591,
-0.1956813,
-0.1501665,
0.5713457,
0.1512607,
-0.1434098,
-0.5764516... |
Blockage of depolarization-induced mitogenesis in CNS neurons by 5-fluoro-2'-deoxyuridine. | Experiments designed to provide further evidence, at the basic metabolic level, that true mitogenesis and mitotic activity are being induced in CNS neurons in response to sustained ionic depolarization were conducted. The ability of 5-fluoro-2'-deoxyuridine (FUdR), a well-studied inhibitor of normal mitogenesis in natu... | 149,581 | [
-0.07526086,
-0.121372,
-0.1860211,
0.03638608,
0.5893981,
-0.2825754,
-0.1196564,
0.10388,
-0.07484196,
0.1473086,
-0.08008426,
0.2452233,
0.0004310137,
0.3139308,
-0.3170526,
0.1370815,
-0.1894369,
-0.007981166,
-0.4576616,
0.2712962,
0.6138188,
0.2124349,
-0.1302195,
... |
Alteration of nucleolar dispersion in prophase by 5-FUdR treatment. | The action of 5-Fluorodeoxyuridine (FUdR) used as an inhibitor of RNA synthesis on the nucleolar evolution during mitosis, has been studied in meristematic cells. Under FUdR treatment the nucleolar dispersion appears as a continuous process, but generally it is not completed and nucleolar remnants remain throughout the... | 149,595 | [
-0.2134139,
-0.004936972,
0.2380322,
0.05234592,
0.3596121,
-0.4247875,
-0.1190331,
0.007697759,
0.278232,
0.00187864,
0.1108318,
0.05942368,
0.01650766,
0.306762,
-0.4290425,
-0.1704029,
-0.1052089,
-0.1103421,
-0.1382592,
0.1182417,
0.3281776,
0.199352,
-0.1012591,
-0... |
Ultrastructural deformation of collagen. | Ultrastructure deformation studies of reconstituted and native rat tail tendon collagen revealed that deformation occurs primarily in the non-staining and presumably non-polar proline rich regions for all ages examined. At low deformation (tension and compression) the deformation occurs somewhat more between the a2 and... | 149,647 | [
-0.1099036,
0.03772878,
-0.2316967,
0.1246547,
-0.1654774,
-0.3971237,
0.04496959,
0.1091974,
0.2316922,
0.09438509,
-0.1800674,
-0.131047,
-0.0239165,
0.0769365,
-0.2087337,
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0.1756718,
0.0690932,
-0.2522725,
0.2709575,
0.09919161,
0.1476627,
-0.1533588,
-0.... |
On the kinetics of the reaction between human antiplasmin and a low-molecular-weight form of plasmin. | The reaction between antiplasmin (A) and a low-molecular-weight form of plasmin (P) proceeds in at least two steps: a fast reversible second-order reaction followed by a slower irreversible first-order transition, and may be represented by: P +A k1 in equilibrium k-1 PA k2 leads to PA'. The low-Mr plasmin, which is obt... | 149,657 | [
0.06172441,
-0.1674995,
-0.3949921,
0.1134807,
0.1713205,
0.02120651,
-0.1092132,
0.2698965,
0.2111322,
-0.05183852,
0.05368815,
0.473305,
0.203195,
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0.33929,
0.2625242,
0.04602025,
0.3994811,
0.08318832,
-0.1326353,
-0.0... |
Silver stain reveals nucleolus organizer regions on a satellited Yq chromosome. | Chromosomes from a patient with a satellited Yq were stained with a silver procedure that differentially stains nucleolus organizer regions. The Yqs stained heavily in all cells examined, indicating the presence of ribosomal cistrons at this region. The Yqs also entered into satellite associations with the D and G grou... | 149,754 | [
0.02630738,
0.3459055,
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0.09092497,
-0.09525958,
-0.03539834,
-0.3791505,
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0.1932262,
0.1785895,
0.2005547,
0.2014621,
0.1472674,
0.1532558,
-0.3080792,
-0.2366833,
-0.3287597,
-0.1346333,
-0.002226435,
-0.2926216,
0.49231,
0.0765087,
-0.06392684,
... |
Replication of chromosomal DNA in cultured abnormal human cells. | The replication of chromosomal DNA in a series of abnormal human cell cultures has been studied by means of DNA-fiber autoradiography. In lymphocytes with trisomy 21, in fibroblasts of 45,X;47,XXX;49,XXXXY; and 49,XXXXX chromosomal constitution, and in fibroblasts from a patient with xeroderma pigmentosum (De Sanctis-C... | 149,757 | [
-0.1666121,
-0.4074109,
-0.1629241,
0.1364054,
0.284795,
0.08122371,
-0.2846756,
0.0751155,
0.06637747,
0.2185068,
0.07579716,
0.1501893,
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0.01768684,
-0.6819379,
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-0.5036816,
0.1214453,
-0.02832917,
0.2616133,
0.5078176,
0.2743541,
-0.1621019,
-0.... |
Cardiac hypertrophy in response to dynamic conditioning in female athletes. | Ten female field hockey players were studied to determine if prolonged dynamic conditioning results in an increased left ventricular internal dimension at end diastole (LVIDD) and if this increase correlates with maximal oxygen consumption (VO2max). At peak season, echocardiograms were obtained and VO2max determined du... | 149,777 | [
-0.2214391,
0.3683172,
-0.2291791,
0.01753004,
-0.09144644,
-0.3249494,
-0.01634723,
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-0.3056254,
-0.1900149,
0.2065193,
0.2316193,
-0.1949891,
-0.05828732,
-0.4070663,
-0.4440361,
-0.14759,
0.163037,
-0.282798,
-0.1088345,
-0.0247349,
0.05244284,
-0.130907,
... |
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