title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Cellular differentiations and structural characteristics in nasopharyngeal angiofibromas. An electron-microscopic study. | An electron-microscopic study of 9 nasopharyngeal angiofibromas was performed in order to elucidate the ultrastructural characteristics. Stromal fibroblasts and proliferating cells of the microvasculature were found. The stromal fibroblasts were subdivided into 3 different groups: (1) "classical" fibroblasts, (2) fibro... | 184,584 | [
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[Concentration of cytoplasmic RNA in the endometrium in trophoblastic disease]. | The method of cytospectrophotometry was used to determine quantitatively the content of cytoplasmatic RNA in cells of endometrial glands in 28 females who suffered trophoblastic disease. It was found that during the first year after the disease the RNA content in the endometrium in patients, subjected to chemotherapy, ... | 184,591 | [
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[Cytoid bodies in basal cell epithelioma]. | 100 basal cell epitheliomas were surveyed for the presence of cytoid bodies by histological and histochemical techniques. By this means a differentiation of the following structures was possible: 1. Elastic globes were present in 32 specimens. Their localisation corresponded in part to the typical subepidermal situatio... | 184,612 | [
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[Anatomical and clinical deliberations on the phyllodes tumor of the breast]. | The authors report on three phyllod Tumours of the breast, two benign and one malignant conditions. They insist on the histological aspect of the tumour, underlining that in the benign forme both, epithelial and mesenchymal components does not present atypies, while in the malignant form only the mesenchymal component ... | 184,625 | [
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Metabolism of mono- and diacylglycerols in subcutaneous adipose tissue of obese and normal-weight subjects. | Tissue monoacylglycerols (MG), diacylglycerols (DG), free fatty acids (FFA), and cyclic AMP (cAMP) and release of FFA and glycerol have been studied in vitro in subcutaneous adipose tissue of 6 obese and 7 normal-weight subjects. The tissue was incubated without or with 6 X 10(-5) mol/l of isoprenaline (ISNA). The DG l... | 184,690 | [
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Acute unilateral adrenal hemorrhage following ACTH administration in a patient with Cushing's syndrome. | A patient with Cushing's syndrome and a concomitant unilateral adrenal hemorrhage following ACTH administration is described. Although stress is commonly associated with the onset of adrenal hemorrhage, a pathologically documented adrenal hemorrhage has not been previously in association with ACTH administration in Cus... | 184,710 | [
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Therapeutic effects of heparin on Pseudomonas-induced corneal ulceration. | Fifty organisms of Pseudomonas aeruginosa were injected intralamellarly in both eyes of 60 albino rabbits. Twenty-four hours later, all eyes were graded and stratified into six groups of ten rabbits with equivalent infections. Treatment was begun with gentamicin alone or 0.3% polymyxin B alone, and in combination with ... | 184,711 | [
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[The mechanism of releasing and bio-behavioral significance of the hypothalamo-hypophyso-adrenal gland reaction to the environment (alarm reaction)]. | Laboratory experimentation has demonstrated the large increase in the rate of circulating norepinephrin (N.E.), in a parallel with an improvement in cardiovascular dynamism of suprarenalectomized rabbits under the action of injection IV of hydrocortisone. As from this ascertainment, the author attempts to make a synthe... | 184,731 | [
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[Pseudohypothyroidism. Complementary results apropos of 4 familial cases]. | In a sibship, 4 out of 5 children featured pseudo-hypoparathyroidism. The following points were verified: hypocalcaemia; increase of the serum level of PTH; normal response of bone and gut effectors to endegenous PTH; contrast between normal bone X-rays and lesions detected by histological studies. | 184,751 | [
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Bilateral sixth nerve palsy. Analysis of 125 cases. | Bilateral abducens nerve pareses were nearly as common as unilateral cases in an inpatient setting (125:143). Cerebrospinal fluid abnormalities were more frequent among the bilateral cases, but generally the same causes produced unilateral and bilateral sixth nerve palsy. The relative ease of diagnosis was in contrast ... | 184,766 | [
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Serum lipid profiles in patients of myocardial infarction in the Chandigarh area (Northern India). | To study the incidence of hyperlipoproteinaemia in patients with myocardial infarction (MI) in the Chandigarh area, estimations of various lipids have been carried out in 83 patients. A serial study has been carried out in 31 patients. Serum lipoproteins and uric acid were also estimated. Results show an incidence of o... | 184,798 | [
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The effect of collagenase on surface markers of human peripheral lymphocytes. | The effect of collagenase on the 'T' and 'B' markers of peripheral blood lymphocytes was studied in five healthy male blood donors. No significant difference between untreated and collagenase treated lymphocytes was found. Collagenase is recommended for use in liberating living cells from skin biopsy specimens. | 184,815 | [
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Oxidation and reduction of membrane-bound cytochrome c in Hemophilus parainfluenzae. Reaction with oxygen, hydrogen peroxide and nitrate. | Cytochromes of the a-, b-, c- and d-type become reduced when intact cells of Hemophilus parainfluenzae have become anaerobic following respiration with substrates such as formate or succinate, as shown previously (J. Biol. Chem. (1970) 254, 5096-5100). In the presence of formate after depletion of O2, there is an unusu... | 184,842 | [
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In vivo study of free and esterified cholesterol turnover in various tissues of the rat. | Rats were infused for 3.5 to 10 hrs with either red cells or plasma previously labelled in vivo by [3H]-cholesterol. Cholesterol specific radioactivities were measured in plasma, HDL, LDL and VLDL, and various tissues. Red cell infusions led to a higher labelling of free than of esterified cholesterol in the plasma of ... | 184,847 | [
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[Kinetic properties and heat resistance of the peritoneal leukocyte myeloperoxidase of white mice]. | The dependence of the myeloperoxidase-catalyzed reaction in the concentration of the enzyme and that of both substrates (hydrogenperoxide and o-dianizidine) was investigated. The substrates--velocity curves appeared non-hyperbolic, an inhibitory effect was registered for both substrates. Hill coefficient with a varying... | 184,851 | [
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[Participation of 5'-deoxyadenosyl-B12 in regulating methylation of tRNA]. | The effects of different forms of cobalamines on the activities of tRNA-methylases of Zajdela ascite hepatoma were studied. Of six cobamides studied 5'-deoxyadenosyl-B12 and factor B containing as a ligand HSO3 in the concentrations of 2.4-10(-5) and 4.8-10(-5) M inhibited the tRNA-methylase activity by 21% and 15% co... | 184,852 | [
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[Extramitochondrial energy dependent synthesis of inorganic pyrophosphate in yeasts]. | In yeast Saccharomyces N.C.Y.C. 644SU3 the simplest energy donor, inorganic pyrophosphate, can be formed not only in the processes coupled with the respiratory chain, but also under conditions when mitochondrial synthesis of the compound is inhibited (glucose repression, anaerobiosis). Stimulation of inorganic pyrophos... | 184,856 | [
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Isolation and characterization of plasma membrane from rat mesenteric arteries. | A method for isolating a plasma membrane-enriched fraction and other subcellular fractions from rat mesenteric arteries by the use of a discontinuous sucrose density gradient is decribed. Electron microscopy showed both plasma membrane and endoplasmic reticulum fractions to be composed of vesicles. 5'-Nucleotidase, alk... | 184,863 | [
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[Ultrastructural aspects of cells with 3 beta-HSDH (delta 5-3 betahydroxysteroid dehydrogenase) activity in female ducks. II. Female Barbary ducks (Cairina moschata)]. | The cells making up the thin internal theca of the follicle of the Barbary duck and which contain are 3 beta HSDH enzyme show all of the ultrastructural characteristics of steroid cells: a well-developed smooth reticulum, tubular cristae mitochondria, a considerable load in lipid inclusionologous cells of the Peking du... | 184,892 | [
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Lactate dehydrogenase from autotrophic and heterotrophic cells of the marine diatom Cylindrotheca fusiformis Reimann & Lewin. | Cultures of Cylindrotheca furisormis grown either autotrohpically or heterotrophically on lactate contained significant amounts of NAD-dependent L(+)-lactate dehydrogenase (EC 1.1.1.27). Polyacylamide gel electrophoresis of crude enzyme extracts revealed a single band which was indistinguishable between autotrohpic and... | 184,899 | [
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Distribution of adenosine triphosphatase in infiltrating ductal carcinoma and non-neoplastic breast. | The histochemical reaction for adenosine triphosphatase (ATPase) has previously been used to differentiate myoepithelial from epithelial cells in the breast and to investigate the possible contribution of myoepithelial cells to mammary carcinoma. Discrepancies in published reports prompted this study of ATPase in non-n... | 184,914 | [
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Cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in normal and chronic lymphocytic leukemia lymphocytes. | The specific activity of cyclic adenosine 3':5'-monophosphate phosphodiesterase was measured in lymphocytes isolated from the blood of normal subjects, from patients with chronic lymphocytic leukemia, and from tonsil tissue. The mean specific activity of cyclic adenosine 3':5'-monophosphate phosphodiesterase in the lym... | 184,920 | [
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The metabolism-dependent maintenance of cell volume and ultrastructure in slices of Morris hepatoma 3924A. | The changes in water and electrolyte content of slices of Morris hepatoma 3924A induced by various conditions of incubation have been compared with the ultrastructural appearance of the tissue. Incubation at 1 degrees led to an increase of water, Na+, and Cl- content and to a loss of K+. There was simultaneous increase... | 184,926 | [
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The limiting effect of transfer RNA's on the rate of protein synthesis in cell extracts of rapidly growing tumors. | Using crude cell extracts from rapidly growing animal and human tumors, we found that (a) the addition of homologous transfer RNA (tRNA) to these extracts stimulated polypeptide synthesis two-to threefold, while addition of heterologous tRNA did not have a similar effect; (b) addition of homologous as well as heterolog... | 184,937 | [
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Biosynthesis of albumin via a precursor protein in Morris hepatoma 5123tc. | The mechanism of albumin biosynthesis was studied in Morris hepatoma 5123tc in vivo and in hepatoma cell suspensions obtained by solubilizing the intercellular matrix with collagenase and hyaluronidase. In the in vivo experiments, L-[-14C]leucine was injected i.v. into rats bearing hepatomas in the muscles of both hind... | 184,940 | [
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Exocrine pancreas under experimental conditions. I. Formation of paracrystalline inclusions in vivo. | After the application of parachlorophenylalanine (pCPA), an amino acid analogue, paracrystalline inclusions are observed in the exocrine pancreas of the rat. The formation of the paracrystalline structures varies according to the dose and the time of examination. Although the first alterations can be seen in the Golgi ... | 184,955 | [
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The general occurrence of intramitochondrial crystals in Hydra cells. | Intramitochondrial crystals are found in normal Hydra as well as in animals undergoing various conditions (budding, regenerating, eserine-treated, and sexual). They appear in all regions of the animal, but seem to be more prevalent at or near the extremities: hypostome, tentacles and basal disk. They are found in all o... | 184,956 | [
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Nature of the interaction between low-density lipoproteins and polyanions and metal ions, as exemplified by heparin and Ca2+. | I examined the effect of lipid concentration on the interaction of the very-low density and low-density lipoproteins in serum with heparin and calcium. A precipitate forms when partly delipidated serum is subjected to the polyanion-metal ion system. Although this precipitate is less turbid than the complexed lipoprote... | 184,985 | [
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Feline malignant giant cell tumor of bone associated with C-type virus particles. | A malignant giant cell tumor of bone in a cat is described. Numerous C-type particles were found budding from the neoplastic cells. Viruses have not previously been associated with malignant bone noeplasms in cats. | 185,002 | [
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Acidosis activation of the pituitary-adrenal-renal glutaminase I axis. | Previous studies have demonstrated that the adrenal glands were necessary for acidosis activation of the mitochondrial glutaminase I pathway. The present studies were undertaken to determine if corticosterone levels are elevated in acidotic rats and if so, whether acidosis stimulates the adrenal glands directly or via ... | 185,045 | [
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An approach to the antigenic structure of arginine kinase and creatine kinase. Physical, chemical and immunological study of some modified derivatives. | The antigenic structure of arginine kinase and creatine kinase has been approached using chemical modifications and enzymatic cleavage. Mild performic oxidation that, with a restricted number of oxidized amino acid residues, results for both enzymes in a severe decrease of the helical structure and in a large increase ... | 185,053 | [
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Kinetics of insulin secretion in chronic pancreatitis and mild maturity onset diabetes. (Evidence for "gut hormone" action beyond glucoreceptor and cyclic adenosine monophosphate mediated insulin release). | We studied insulin responses to glucose with and without cholecystokinin-pancreozymin and aminophyllin infusions in normal, chronic pancreatitic and genetic (maturity-onset) diabetic subjects. Glucose was given alone as separate 5 and 10 g boluses followed by infusion at 250 mg/min. and 500 mg/min., respectively. Chron... | 185,056 | [
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Primary and secondary in vitro generation of cytolytic T lymphocytes in the murine sarcoma virus system. | Cell-mediated cytotoxic responses in vitro to surface antigens associated with murine sarcoma virus (MSV)-induced tumors were investigated using mixed leukocyte-tumor cell cultures (MLTC). The source of responding cells was either spleens from normal C57BL/6 mice (primary MLTC) or spleens of C57BL/6 mice carrying or ha... | 185,057 | [
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Receptors for immune complexes on cells within a polyoma virus-induced murine sarcoma. | Cells present in the polyoma virus-induced murine ascites tumor SEYF-a showed the capacity to fix soluble immune complexes of ovalbumin anti-ovalbumin. The fixation could be inhibited by preincubating the cells with antisera directed against H-2 antigens and with syngeneic anti-tumor antibodies. The latter did not reac... | 185,060 | [
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... |
Angiotensin antogonists as pharmacological tools. | The availability of specific competitive antagonists stimulated investigation of the physiological and pathological role of angiotensin (A-II) and permitted the qualitative and quantitative characterization of numerous angiotensin receptor sites. The specific, competitive antogonists for A-II inhibit both the direct ac... | 185,093 | [
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Renin--angiotensin antagonists and the regulation of blood pressure. | The role of the renin--angiotensin system in the regulation of blood pressure in dogs and in human subjects was assessed by the use of the nonapeptide converting enzyme inhibitor (CEI), permitting the following conclusions: 1) In the normal, sodium replete dog, the renin--angiotensin system plays little role in the reg... | 185,095 | [
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0.07742762,
0.055631... |
Evidence of depolarization-induced cAMP increase in the superior cervical ganglion of several mammalian species. | 1. The activation of cAMP synthesis resulting from exposure of superior cervical ganglion (SCG) tissue to high K+ solutions observed in calf has been found to occur in three other mammalian species, namely rat, cat, and rabbit. 2. The cAMP accumulation in the ganglion of calf is much less pronounced than that occurring... | 185,121 | [
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Markers to distinguish normal and neoplastic mammary epithelial cells in vitro: comparison of saturation density, morphology and concanavalin A reactivity. | Normal and premalignant mouse mammary epithelial cells can be prepared in high yields by collagenase dissociation of minced glands followed by a brief, differential centrifugation to remove contaminating fibroblasts and fat cells. The major difficulties in preparing pure cultures in quantity are 1) incomplete dissociat... | 185,159 | [
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... |
Hypertensive virilizing adrenal hyperplasia with minimal impairment of synthetic route to cortisol. | One of the first described cases of hypertensive virilizing adrenal hyperplasia (VAH) (Pediatrics 8: 805, 1951) has been followed from age 2 1/2 until age 26. Blood pressure as an infant was 150/90, and at age 25 was 220/160. During childhood the patient was lost to follow-up for prolonged periods, and received no ther... | 185,231 | [
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0.570541,
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Gonadotropin output in congenital adrenal hyperplasia before and after adrenal suppression. | Basal release of gonadotropin and the response to an infusion of 100 mug of synthetic luteinizing hormone releasing hormone (LRH) were studied in a teenage girl with congenital adrenal hyperplasia (CAH). The initial study was done during a period of poor adrenal suppression, and second study was done after adequate adr... | 185,235 | [
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Chemotherapeutic compounds and Acanthamoebae from eye infections. | The amoebicidal and amoebistatic action in vitro of 24 compounds was tested on two strains of Acanthamoeba, A. polyphaga and A. castellanii, isolated from eye infections in this country. For comparison, the Ryan strain of A. castellanii and Naegleria gruberi L-1 were also examined. Nine compounds showed sufficient acti... | 185,240 | [
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... |
Characterization of Ia antigens in mouse serum. | Sera obtained from normal B10.BR mice were shown to inhibit selectively a specific anti-Ia alloantiserum. Partial purification of the Ia antigenic activity was accomplished by isolation of the high density lipoproteins from these sera by fractional precipitation with sodium phosphotungstate and MgCL2. Both H-2.23 and I... | 185,298 | [
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Normal rabbit alveolar macrophages. I. The phagocytosis of tubular myelin. | Normal rabbit alveolar macrophages are engorged with large, dense inclusions which contain whorls of myelin figures, suggesting an exogenous source of polar lipids in their diet. One contributory source of such lipids is surfactant, since macrophages were seen ingesting tubular myelin and vacuoles containing remnants o... | 185,317 | [
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Normal rabbit alveolar macrophages. II. Their primary and secondary lysosomes as revealed by electron microscopy and cytochemistry. | In this investigation, vacuoles containing tubular myelin proved to be digestive compartments with cytochemical reactivity for acid phosphatase and arylsulfatase. These cytochemical markers identify the secondary lysosomes, known to contain enzymes capable of hydrolyzing phospholipids like surfactant. Therefore, it app... | 185,318 | [
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Plaque formation with influenza viruses in dog kidney cells. | Infectious influenza and parainfluenza viruses were produced as plaql passages of egg-grown viruses in MDCK monolayers. Virus titres of 10(6) to 10(11) p.f.u./ml were obtained for several A and B strains of influenza and parainfluenza viruses. | 185,324 | [
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Analysis of the RNA species isolated from defective particles of vesicular stomatitis virus. | Serial high multiplicity passage of a cloned stock of vesicular stomatitis virus was found to generate defective interfering particles containing three size classes of RNA, with sedimentaiton coefficients of 31 S, 23 S and 19 S. The 31 S and 23 S RNA species were found to be complementary to both the 12 to 18 S and 31 ... | 185,328 | [
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0.01039568,
0.03474955... |
Studies on the comparative pharmacology and selective toxicity of tricaine methanesulfonate: metabolism as a basis of the selective toxicity in poikilotherms. | Tricaine methanesulfonate, administered at a dose of 150 mg/kg i.p., produced a flaccid paralysis and loss of the righting reflex in a number of poikilothermic species including the frog. Leopard frogs (Rana pipiens) given 150 mg/kg i.p. regained the righting reflex at 113 +/- 28 (S.D.) minutes after injection. A simil... | 185,356 | [
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Nursing consultation: a clinical specialty. | In summary, the Mental Health Nurse Consultant is committed to the belief that nursing staff are competent to implement appropriate mental health care. Because of this the consultant utilizes both resource and process consultation to assist staff in determining care plans and to support a realistic method for delivery.... | 185,377 | [
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... |
Aberrant serum enzyme patterns in dermatomyositis associated with hepatoma. | A Caucasian male developed florid dermatomyositis documented by serum enzyme elevation, electromyography, and histology of skin and muscle. Serum enzymes, including creatine phosphokinase (CPK), aldolase, glutamic oxaloacetic transaminase (SGOT), and lactic dehydrogenase (LDH), decreased initially during high dose syst... | 185,384 | [
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Comparative diagnostic aspects of herpes simplex virus tumor-associated antigens. | Sera from cancer patients and healthy individuals, obtained from two independent sources, were examined for their abilities to react with herpes simplex virus-associated tumor antigens, AG-4 and NVA-TAA (nonvirion antigen-tumor-associated antigen). Both antigens were prepared by infection of HEp-2 cells with herpes sim... | 185,398 | [
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... |
Consequences of herpes simplex virus type 2 and human cell interaction at supraoptimal temperatures. | The consequences of herpes simplex virus type 2 (HSV-2) and human embryonic fibroblast cell interaction at different temperatures (37, 40, and 42 degrees C) were investigated. Incubation at 37 or 40 degrees C was permissive for HSV-2 inhibition of host DNA synthesis, induction of virus-specific DNA replication, and inf... | 185,418 | [
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... |
Origin of polyoma virus-associated endonuclease. | Polyoma virus particles purified from infected cells, but not from the culture medium, exhibited an endonuclease activity distinct from the serum contaminant recently described. This endonuclease cleaved form I polyoma DNA once only per molecule, at one of three possible sites corresponding to the known adenosine-ribos... | 185,421 | [
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Simian virus 40-permissive cell interactions: selection and characterization of spontaneously arising monkey cells that are resistant to simian virus 40 infection. | A fraction of permissive cells survive simian virus 40 (SV40) infection. The frequency of such surviving cells depends only upon the concentration of infecting virus, both parental and progeny, to which the cells are exposed during the course of selection. Surviving clones, which can be freed of virus by cloning in the... | 185,424 | [
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[Total syndactylism with mesomelic shortening of the arm, radioulnar and metacarpal synostoses and disorganization of the phalanges ("cenani syndactylism") (author's transl)]. | An additional case "Cenani syndactylism" in a 7 years-old female child was described. With this autosomal recessive inherited disease, the radius and ulna are severly shortened and generally fused with each other. The metacarpal bones are, for the most part, synostosized. The phalanges are badly disorganized. Usually n... | 185,451 | [
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... |
A telephone follow-up procedure for increasing the effectiveness of a treatment program for alcoholics. | The use of outpatient services by alcoholics can be significantly increased by means of a telephone follow-up procedure. | 185,468 | [
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0.2588127,
-0.2647586,
0.1575039,
0.03902137,
0.1425092,
0.08006366,
0.... |
Myocardial ischemia. | Myocardial ischemia results from an imbalance of energy supply and demand. Because of the essentially aerobic nature of myocardial metabolism and the high oxygen extraction from the blood, ischemia is usually equatable with limitation of blood supply. Coronary atherosclerosis is a patchy disorder, and therefore, ischem... | 185,472 | [
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0.2915839,
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The distribution of plasma lipoproteins in middle-aged male runners. | Stimulated by increasing evidence of an inverse relationship between plasma high-density lipoprotein cholesterol level and frequency of coronary heart disease, we determined concentrations of fasting plasma cholesterol, triglyceride, and lipoproteins in 41 very active men (running greater than 15 miles/wk for the previ... | 185,487 | [
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0.1024559,
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0.5654784,
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... |
Changes in plasma triglyceride metabolism during withdrawal of bile. | The relationship between bile acid turnover and plasma triglyceride metabolism was examined in a group of seven moderately overweight and hypertriglyceridemic men. Bile acid synthesis was stimulated by the continuous aspiration of duodenal contents so that 150% of the bile acid pool was removed in 18 hr. In comparison ... | 185,488 | [
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0.2712988,
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Fatal cadmium-fume pneumonitis. | A 38-year-old man developed acute respiratory distress several hours after welding cadmium-plated drums without taking precautions against the inhalation of fumes. His respiratory distress worsened over the ensuing three and a half days, and he died. Histological examination of the lungs showed changes of acute cadmium... | 185,501 | [
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0.4971187,
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Susceptibility of chickens to avian encephalomyelitis virus. V. Behavior of a field strain in laying hens. | Some 12-month-old laying hens were inoculated orally or subcutaneously with 10(4.7) EID50 of a field strain of avian encephalomyelitis virus. They were examined for propagation of the virus in the body at regular intervals of time. When two hens were sacrificed daily in the group of oral inoculation, the virus was foun... | 185,530 | [
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0... |
[Herpes simplex (author's transl)]. | About 1-2% recurrent herpes simplex infections are seen in adults. In childhood, secondary herpetic infections are very rare. In contrast, primary infections by herpes simplex virus are of great importance: herpes disseminatus neonatorum (type 2), gingivostomatitis herpetica (type 1), eczema herpeticum (type 1; in some... | 185,569 | [
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0.02869367,
0.0006485737,
0.207575,
0.2655636,
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Persistance of intramuscular deposits of vitamin D3 in slaughter pigs. | In pigs given injections of 1.5 mill IU vitamin D3 in oil intramuscularly 9, 5 or 3 weeks before slaughter residues in the depots were very high (table 1). Certain cuts of pork from pigs treated in this way should therefore be regarded as unacceptably polluted. Furthermore the practise of using oily vitamin D preparati... | 185,586 | [
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0.4404905,
0.02732006,
0.0... |
Role of cyclic nucleotides in cell growth and differentiation. | A simple model is depicted below that suggests some unifying principals in the action of cyclic nucleotides in the GO-to-G+ interconversion, differentiation, and transformation (see article). The letters with G+ subscripts (AG+ through EG+) represent cell states at different increasing levels of "determination" (see se... | 185,633 | [
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AG 60.99: A promising contrast agent for computed tomography of the liver and spleen. | AG 60.99, an emulsion of poppy-seed oil, is proposed as a promising organ-specific agent for computed tomography (CT) of the liver and spleen. This agent not only opacifies the hepatic parenchyma enough to enhance visualization of the bile ducts but also demonstrates the vascular anatomy with smaller doses than those r... | 185,647 | [
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0.09799306,
0.3495692,
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0.4002313,
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0.... |
Observing the growth of Wilms' tumor. | Four children ranging in age from 2 1/2 months to 4 years had excretory urography initially for reasons other than evaluation of an abdominal mass. Three patients had repeat urography only after masses became apparent at intervals of 8.5 months, 9 months and 15 months after the initial urogram. The fourth patient was f... | 185,651 | [
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0.5310643,
0.04278556,
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... |
Mitochondrial DNA of Yoshida ascites tumour cells. Physicochemical properties and biological function. | Mitochondrial DNA from Yoshida A.H. 130 cells, has been characterized by determination of the buoyant density by CsCl equilibrium density gradient centrifugation and the thermal denaturation and renaturation behaviour. These studies have been carried out parallelly on nuclear DNA from the same cells in order to search ... | 185,670 | [
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0.124016,
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0.01955291,
0... |
Influence of fat ingestion on lecithin:cholesterol acyl transfer rate in plasma of normal persons. | Lecithin:cholesterol acyl transfer (LCAT) rate in plasma and lipid concentrations in total plasma and high density lipoproteins (HDL) were determined before and after oral fat loads in healthy human subjects. The changes of LCAT rate after fat loading were compared to the effect of chylomicrons or lipid emulsions added... | 185,684 | [
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0.3855223,
0.2056256,
0.1902891,
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... |
[Neuropsychiatric findings in a case of paramyoclonus multiplex]. | In a subject affected with multiple paramyoclonus, showing asyncronous, bilateral, intermittent, spontaneous myoclonic jerks, a neuro-psychiatric investigation was performed. Several day-time poligraphic recordings were normal, while the night-time ones showed the lack of myoclonic jerks throughout the sleep. Metrazol ... | 185,689 | [
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0.03439442,
0.4595578,
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Electrotonic coupling: effective sign reversal by inhibitory neurons. | Neurons in the buccal ganglia of Navanax inermis which control circumferential muscles of the pharynx showed typical electrotonic coupling when there was little synaptic activity in them. When there was much inhibitory activity, the effective sign of coupling was reversed; that is, hyperpolarization and depolarization ... | 185,698 | [
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0.3658696,
0.0384714,
0.05078... |
[Validity of bronchial flow measurement by Wright's air flowmeter. Comparison with maximal expiratory volume in a second]. | The validity of measurement of bronchial air flow, using Wright's air flow meter, was studied comparing the maximum air flow thus obtained with the maximum expiratory volume in one second, used as unit of reference. During a first stage, the reproducibility of the test was determined this was excellent, 3.26% for the m... | 185,717 | [
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... |
The ocular manifestations of herpes zoster, varicella, infectious mononucleosis, and cytomegalovirus disease. | Herpes zoster, caused by varicella-zoster (V-Z) virus which also causes varicella (chickenpox), is usually a benign self-limited disease. However, when the ophthalmic division of the trigeminal nerve is affected, the ocular disease (ophthalmic zoster), although also usually mild and self-limited, may have severe compli... | 185,734 | [
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0.6151162,
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0.270619,
0.2989586,
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0.... |
The biology of herpes simplex virus infection in humans. | Herpes simplex virus is a frequent cause of recurrent ocular, oral, genital or cutaneous eruptions in man. Lesions are highly localized and tend to recur at the same site. Among the most consistent factors provoking recurrence is root section of the trigeminal nerve. Clinical and experimental data suggest that herpes s... | 185,737 | [
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0.2241509,
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0.6369738,
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... |
Immunology of herpesvirus infection: immunity to herpes simplex virus in eye infections. | A gereral, overall pattern of the temporal relationship and interaction between cell and antibody-mediated immune responses following herpes simplex virus infection of the rabbit cornea can be synthesized from our studies. Cell-mediated immunity (CMI) appears early following infection, at a time when mononuclear and ly... | 185,741 | [
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0.189368,
0.07515584,
0.20532,
0.1025448,
... |
Photosynthetic electron carriers at a heptane-water interface. | Surface properties of monomolecular films of chlorophyll (Chl), plastocyanin (Pc), cytochrome c (Cyt) and ferridoxin (Fd) were measured at a heptane-water interface. Mixed films of Chl and the other components were examined in darkness and in light. The area/molecule, A, for Fd (from Cl. pasteurianum) is much larger at... | 185,831 | [
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0.07523263,
0.1876445,
0.2932325,
-0.1121355,
... |
[Effiency in surgery (author's transl)]. | Increase in the cost of medical care force us to adopt "medical rationalisation" instead of as previously "hospital rationalisation". This medical rationalisation constitutes a new, well-thought out way of putting questions about diagnosis, therapy and after-care. We must abandon the opinion that the prestige of a surg... | 185,845 | [
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0.396878,
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0.09785135,
... |
Existence of big and little forms of luteinizing hormone in human serum. | Serum fractions from normal subjects obtained by gel chromatography have been investigated using three different assay systems: radioimmunoassay (RIA), radioligand receptor assay (RRA), and testosterone production assay (TPA). The bulk of immunoassayable and "bioassayable" LH-activity was found in two fractions differi... | 185,871 | [
0.2252526,
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0.04042139,
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0.1685887,
0.175945,
0.1450926,
0.04082161,
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Cortisol effect on collagen biosynthesis in embryonic explants and in vitro hydroxylation of protocollagen. | The effect of increasing doses of hydrocortisone acetate, hydrocortisone phosphoric acid complex, and hydrocortisone sodium succinate on collagen biosynthesis was assayed in two different systems. I. Explants of chicken embryo tibiae showed decreased biosynthesis of [14C]hydroxyproline and total and glycosylated [14C]h... | 185,874 | [
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0.5987055,
0.4388376,
0.02883296,
-0.0606678... |
Zonation of the adrenal cortex. III. Distribution of cytochrome P-450 in the zona glomerulosa of the bovine adrenal cortex. | A microsomal fraction was obtained from the zona glomerulosa of the bovine adrenal cortex. Glucose-6-phosphate activity of the fraction was found to be much lower than that of the liver. Contents of RNA and phospholipids, besides electron microscopic findings, of the fraction also indicate that it is rich in smooth-sur... | 185,878 | [
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0.15... |
Heterotransplantation of experimentally induced dog stomach adenocarcinoma to nude mice. | Heterotransplantation of gastric adenocarcinoma, induced in dog by N-ethyl-N'-nitro-N-nitrosoguanidine (ENNG) has been attempted to nude mouse. Biopsied materials from Borrmann 3 type carcinoma, which showed signet-ring cell carcinoma at the subcardiac region of a beagle dog, were inoculated into the muscles of the hin... | 185,879 | [
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0.2257524,
0.3681394,
0.04579677,
-0.... |
Kidney size and growth in unilateral renal agenesis and in the remaining kidney following nephrectomy for Wilms' tumor. | The kidney size and renal growth were determined in unilateral renal agenesis and in the remaining kidney following nephrectomy for Wilms' tumor. The ultimate length of 98 per cent of the functioning kidneys in renal agenesis is expected not to exceed +5.6 SD. In the tumor series the corresponding figure is +4.2 SD. | 185,883 | [
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Vascular angiotensin receptors and their role in blood pressure control. | The renin angiotensin system has an important role in regulating arterial blood pressure in homeostasis and disease. A reciprocal relationship exists between sodium balance and the circulating levels of renin and angiotensin II. The vascular responsiveness to angiotensin II, the major vasconstrictor component of the re... | 185,902 | [
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... |
Lithium administration and phosphate excretion. | The phosphaturic effect of parathyroid hormone (PTH), cyclic adenosine monophosphate (cAMP), acetazolamide (Az), and HCO3 loading was studied in normal, thyroparathyroidectomized (TPTX), and Li-treated dogs. PTH administration to normal animals markedly increased fractional excretion (F) of PO4 but had a blunted effect... | 185,911 | [
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... |
NAD glycohydrolase activity in hearts with acute experimental infarction. | Myocardial ischemia was produced in dogs by occluding the descending coronary artery. NAD decreased in the ischemic tissue taken 2 h after the arterial ligature, and an equivalent amount of nicotinamide was detected instead. A further breakdown occurred when fragments of ischemic and nonischemic tissue were incubated a... | 185,912 | [
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-0.1281072,
-0.09209115,
-0.3550184,
0.3248822,
-0.4501938,
0.2383887,
-0.2056291,
0.06492349,
0.2083511,
0.2332643,
-0.1442965,
-0.00... |
Impaired urinary concentrating ability and cyclic AMP in K+-depleted rat kidney. | The possibility that an alteration of the vasopressin-dependent cyclic AMP system plays a pathogenic role in the urinary concentrating defect in K+ depletion was investigated in the rat. The antidiuretic response to vasopressin was significantly less in K+-depleted rats. In these K+-depleted rats, the increase in urina... | 185,913 | [
-0.2284173,
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0.1935363,
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0.3541416,
0.03069872,
0.0670543... |
Can program evaluation be saved from its enthusiasts? | Program evaluation--the use of scientific techniques to measure the value of an agency's work--has become the focus of major attention and enthusiasm in mental health service planning and administration. However, the author points out that completed program evaluation studies are few in number and provide no evidence o... | 185,915 | [
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0.2263069,
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0.1921045,
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0.002774309,
0.3298667,
0.1469688,
0.1763351,
... |
Histomorphological and histochemical studies on the preen gland of cortisone-treated male pigeons. | Intramuscular administration of cortisone acetate (5 mg daily to each for 15 days) to adult male pigeons provoked hypertrophy of the preen gland. Desquamation and loss of alveolar differentiated cells were also accelerated to a great extent. Significant changes observed in the histochemical composition of the alveoli o... | 185,924 | [
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0.5127627,
0.217606,
0.06238331,
0.2351412,
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... |
Photoinactivation of latent herpes simplex virus in rabbit kidney cells. | The photoinactivation of actively and nonactively growing herpes simplex virus by neutral red and proflavine was studied in rabbit kidney cells. Active virus growth was inhibited by both dyes under conditions which did not destroy the cells. Neutral red caused a much greater inhibition than proflavine. Neutral red also... | 185,948 | [
0.1097417,
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0.1607874,
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0.... |
Effect of treatment with exogenous interferon, polyinosinic acid-polyctyidylic acid or polyinosinic acid-polycytidylic acid-poly-L-lysine complex on encephalomyocarditis virus infections in mice. | The effect of treatment with exogenous interferon was compared with two interferon inducers, polyinosinic acid-polycytidylic acid [poly(I:C)] and [poly(I:C)]-poly-l-lysine complex (P-L-L complex), in two model encephalomyocarditis virus infections of mice. Although both inducers stimulated the production of interferon,... | 185,951 | [
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0.05423692,
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0.09012377,
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0.03698818,
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0.01132048,
0.4304709,
0.3338339,
0.2285427,
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... |
Virus movement in soil columns flooded with secondary sewage effluent. | Secondary sewage effluent containing about 3 X 10(4) plaque-forming units of polio virus type 1 (LSc) per ml was passed through columns 250 cm in length packed with calcareous sand from an area in the Salt River bed used for ground-water recharge of secondary sewage effluent. Viruses were not detected in 1-ml samples e... | 185,960 | [
-0.2323341,
0.1587167,
0.0171506,
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0.04634034,
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0.2964358,
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0.2412711,
0.1023764,
-0.1059... |
Calcium and phosphorus homeostasis in man. Effect of corticosteroids. | Serum calcium and phosphorus levels, urinary excretion rates of calcium, phosphorus, and cyclic adenosine monophosphate (cAMP), and plasma parathyroid hormone (PTH) concentrations were determined in 11 normal subjects and in nine patients maintained on long-term prednisone therapy for chronic obstructive pulmonary dise... | 185,973 | [
-0.1067361,
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0.2068778,
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0.1342247,
0.1775309,
0.3000988,
-0.0232580... |
A mucosal disease virus as a cause of abortion, hairy birth coat and unthriftiness in sheep. 2. Observations on lambs surviving for longer than seven days. | A condition in Australian sheep resembling border disease was transmitted by the inoculation of pregnant ewes with material from affected lambs. This material contained mucosal disease virus (MDV). Twenty-two lambs comprising 6 from uninoculated control ewes, together with 11 with hairy coats and 5 with normal coats fr... | 186,000 | [
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0.2728172,
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0.2016154,
0.08620013,
0.03417229,
... |
An adenovirus from a turkey pathogenic to both chicks and turkey poults. | An adenovirus, designated T-75 isolant, was isolated from the cloacal swab of a clinically normal turkey, 13 weeks old. The T-75 isolant was identified as an adenovirus on the basis of physicochemical properties, cytopathology, and agar-gel precipitin test. Producing two-way cross-neutralization reactions with CELO vir... | 186,010 | [
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0.2813359,
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-0.1081439,
... |
Demonstration of Eimeria tenella in bursa of Fabricius of chickens. | Coccidial life-cytle stages were detected in the bursa of Fabricius of broiler chickens inoculated with Eimeria tenella, whether or not the chickens had previously been infected with infectious bursal disease virus (IBDV). Chickens infected only with E. tenella had developing parasites in the lining epithelium, whereas... | 186,013 | [
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0.04705574,
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0.04943312,
0.3520803,
0.09321517,
0.142695... |
Iso-cytochrome c species from baker's yeast. Analysis of their circular-dichroism spectra. | The circular-dichroism spectra of baker's-yeast iso-1- (methylated and unmethylated forms) and iso-2-cytochrome c species were examined between 200 and 600nm. In the visible region the yeast haemoproteins have characteristics nearly indistinguishable from those of horse heart cytochrome c. From the spectra in the u.v. ... | 186,031 | [
-0.4663591,
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0.4205047,
0.4369952,
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-0.... |
Adenosine and adenine nucleotides stimulation of skin (epidermal) adenylate cyclase. | Adenosine, AMP, ADP and ATP activated adenylate cyclase in pig skin (epidermis) slices resulting in the accumulation of cyclic AMP. This effect was highly potentiated by the addition of the cyclic AMP-phosphodiesterase inhibitor, papaverine. But another inhibitor, theophylline, strongly blocked the activation of adenyl... | 186,102 | [
0.1204325,
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0.3921306,
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0.02442484,
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0.5104929,
0.1970406,
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0.... |
Effect of substance P and eledoisin on K+ efflux, amylase release and cyclic nucleotide levels in slices of rat parotid gland. | The undecapeptides, substance P and eledoisin, caused a rapid, concentration-dependent increase in K+ efflux and amylase release from parotid tissue slices. The effects were not blocked by beta-adrenergic, alpha-adrenergic, or cholinergic antagonists. Incubation buffer calcium was required for stimulation of K efflux a... | 186,104 | [
-0.3040143,
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0.1769872,
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0.1649489,
-0.3445405,
-0.124049... |
Comparison of zymogram of three lymphoblastoid cell lines with a new microtechnique. | The enzymatic activities of three lymphoblastoid cell lines were subjected to a comparative analysis of 22 enzymatic activities with a new microtechnique "Apizym". This method is easy, requires only a small number of cells and allows simultaneous testing of many enzymatic activities from the same sample. The three cell... | 186,133 | [
0.05699496,
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0.009196364,
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0.3609068,
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0.1830146,
0.2057817,
0.1786855,
0.2740704,
-0.1579753,
-0.07272406,... |
Radiogenic free radicals in apatite: the influence of fluoride and hydroxide. | Fluor-hydroxyapatites of varying fluoride and hydroxide contents were irradiated by soft x-rays at -188 degrees C and examined by means of electron spin resonance spectroscopy. Variation in fluoride-hydroxide contents affected radical yield and resulted in the observation of two kinds of oxygen anion resonances: a doub... | 186,164 | [
-0.2762791,
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0.0565916,
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0.06791379,
0.4034198,
0.2672332,
-0.1672376,... |
Radical partial renal irradiation. an alternative to partial nephrectomy in bilateral Wilms' tumor. | A 6-year-old girl with simultaneous bilateral Wilms' tumor was treated with a radical nephrectomy on the side of more extensive involvement, followed by postoperative renal bed irradiation (3500 rads over 32 days) and radical partial renal irradiation (4000 rads over 35 days) to the contralateral disease. Concurrent an... | 186,179 | [
-0.2952609,
0.2906613,
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0.3497026,
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0.04750419,
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0.03427145,
0.182286,
0.3270081,
0.6328134,
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0.1568016,
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0.04242554,
0.006170942,
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0.4421859,
0.006792084,
-0.201407,
0.3... |
Extraneuronal effects of 6-hydroxydopamine and extraneuronal uptake of noradrenaline. In-vivo and in-vitro studies on adrenocortical cells of lizards and rats. | 6-hydroxydopamine (6-OHDA) was shown to cause ultrastructural changes in adrenocortical cells of lizards and rats. These changes comprised the formation of dense bodies with lamellar and crystalloid patterns, a decrease in the number of mitochondria and structural alterations of mitochondria. Alterations in adrenomedul... | 186,189 | [
-0.1962243,
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0.172181,
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0.149629,
0.01367108,
0.2357202,
0.2564122,
0.05491453,
0.07671143,
... |
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