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Royal Scottish National Hospital Over two hundred patients had stayed in the institution by 1874; however, there was a limit to how long a patient could stay which was five years. In 1875 the need for another extension had become apparent, the expansion would allow for a further 120 patients to live in the institution, the cost had been estimated at £12,000. By 1877 most of the new building had been completed, and patients had begun to live in the portion of the building that had been completed. The gymnasium and the rest of the new building were completed by 1878; patients families had been requesting to have accommodation to stay with younger patients during their time at the institution which the committee was to meet and discuss. By 1881 the grounds had been fenced, and new sewage pipes had been fitted. Dr. Ireland resigned in 1882 and was replaced in the role by Mr. Alexander Skene, for medical knowledge Dr. Hamilton became the medical officer to work alongside Mr. Skene in the running of the institution. Mr. Skene worked to show the positive points of having patients working on a task where they could see the difference they were making, boys worked hard in the garden and fields if they were fit enough to do so and girls enjoyed helping in the garden as well as their knitting and needlework. Mr. Skene had all the day-rooms and dormitories freshly decorated to promote a cheerful environment for all the patients that lived in the institution. Mr. Skene received a commendation from the Commissioners of Lunacy in 1883, Dr
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Amortising swap An is usually an interest rate swap in which the notional principal for the interest payments declines (i.e. is paid down) during the life of the swap, perhaps at a rate tied to the prepayment of a mortgage or to an interest rate benchmark such as the London Interbank Offered Rate (Libor). It is the opposite of the accreting swap. If the swap allows for uncertain contingent ups and downs in the notional principal, it is called a "roller-coaster swap". Sources Further reading
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Stereophonic sound In the Westrex system, each channel drives the cutting head at a 45-degree angle to the vertical. During playback, the combined signal is sensed by a left-channel coil mounted diagonally opposite the inner side of the groove and a right-channel coil mounted diagonally opposite the outer side of the groove. The Westrex system provided for the polarity of one channel to be inverted: this way large groove displacement would occur in the horizontal plane and not in the vertical one. The latter would require large up-and-down excursions and would encourage cartridge skipping during loud passages. The combined stylus motion is, in terms of the vector, the sum and difference of the two stereo channels. Effectively, all horizontal stylus motion conveys the L+R sum signal, and vertical stylus motion carries the L−R difference signal. The advantages of the 45/45 system are that it has greater compatibility with monophonic recording and playback systems. Even though a monophonic cartridge will technically reproduce an equal blend of the left and right channels, instead of reproducing only one channel, this was not recommended in the early days of stereo due to the larger stylus (1.0 mil vs 0.7 mil for stereo) coupled with the lack of vertical compliance of the mono cartridges available in the first ten years of stereo. These factors would result in the stylus 'digging into' the stereo vinyl and carving up the stereo portion of the groove, destroying it for subsequent playback on stereo cartridges
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Space industry Some future developments of the space industry that are increasingly being considered include new services such as space tourism. From 2004–2013, total orbital launches by country/region were: Russia: 270, US: 181, China: 108, Europe: 59, Japan: 24, India: 19 and Brazil: 1. Relevant trends in the 2008–2009 for the space industry have been described as: The 2019 Space Report estimates that in 2018 total global space activity was $414.75 Billion. Of that, the report estimates that 21%, or $87.09 Billion, was from U.S. Government Space Budgets.
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Nano-thermite A method for producing nano scale, or ultra fine grain (UFG) aluminum powders, a key component of most nano-thermitic materials, is the dynamic gas-phase condensation method, pioneered by Wayne Danen and Steve Son at Los Alamos National Laboratory. A variant of the method is being used at the Indian Head Division of the Naval Surface Warfare Center. The powders made by both processes are indistinguishable. A critical aspect of the production is the ability to produce particles of sizes in the tens of nano-meter range, as well as with a limited distribution of particle sizes. In 2002, the production of nano-sized aluminum particles required considerable effort, and commercial sources for the material were limited. Current production levels are now beyond 100 kg/month. An application of the sol-gel method, developed by Randall Simpson, Alexander Gash and others at the Lawrence Livermore National Laboratory, can be used to make the actual mixtures of nano-structured composite energetic materials. Depending on the process, MICs of different density can be produced. Highly porous and uniform products can be achieved by super-critical extraction. As with all explosives, research into control yet simplicity has been a goal of research into nanoscale explosives. Some can be ignited with laser pulses. MICs have been investigated as a possible replacement for lead (e.g. lead styphnate, lead azide) in percussion caps and electric matches. Compositions based on Al-BiO tend to be used. PETN may be optionally added
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Engineering economics (civil engineering) Civil engineers under constant pressure to deliver infrastructure effectively and efficiently confront complex problems associated with allocating scarce resources for ensuring quality, mitigating risk and controlling project delivery. Civil engineers must be educated to recognize the role played by engineering economics as part of the evaluations occurring at each phase in the project lifecycle. Thus, the application of engineering economics in the practice of civil engineering focuses on the decision-making process, its context, and environment in project execution and delivery. It is pragmatic by nature, integrating microeconomic theory with civil engineering practice but, it is also a simplified application of economic theory in that it avoids a number of microeconomic concepts such as price determination, competition and supply and demand. This poses new, underlying economic problems of resource allocation for civil engineers in delivering infrastructure projects and specifically, resources for project management, planning and control functions. Civil engineers address these fundamental economic problems using specialized engineering economics knowledge as a framework for continuously “… probing economic feasibility…using a stage-wise approach…” throughout the project lifecycle
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Spider silk is used to suspend inertial confinement fusion targets during laser ignition, as it remains considerably elastic and has a high energy to break at temperatures as low as 10–20 K. In addition, it is made from "light" atomic number elements that won't emit x-rays during irradiation that could preheat the target so that the pressure differential required for fusion is not achieved. Replicating the complex conditions required to produce fibres that are comparable to spider silk has proven difficult in research and early-stage manufacturing. Through genetic engineering, "Escherichia coli" bacteria, yeasts, plants, silkworms, and animals have been used to produce spider silk proteins, which have different, simpler characteristics than those from a spider. Artificial spider silks have fewer and simpler proteins than natural dragline silk, and are consequently half the diameter, strength, and flexibility of natural dragline silk.
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Lunar space elevator The lunar elevator could also be used to transport supplies and materials from the surface of the moon into the Earth's orbit and vice versa. According to Jerome Pearson, many of the Moon's material resources can be extracted and sent into Earth orbit more easily than if they were launched from the Earth's surface. For example, lunar regolith itself could be used as massive material to shield space stations or crewed spacecraft on long missions from solar flares, Van Allen radiation, and other kinds of cosmic radiation. The Moon's naturally occurring metals and minerals could be mined and used for construction. Lunar deposits of silicon, which could be used to build solar panels for massive satellite solar power stations, seem particularly promising. One disadvantage of the lunar elevator is that the speed of the climbing vehicles may be too slow to efficiently serve as a human transportation system. In contrast to an Earth-based elevator, the longer distance from the docking station to the lunar surface would mean that any "elevator car" would need to be able to sustain a crew for several days, even weeks, before it reached its destination.
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Attachment theory The anxiety comes from an individual's intense and/or unstable relationship that leave the anxious or preoccupied individual relatively defenseless. Adults with this attachment style tend to look way too far into things, whether that's a text message or a face-to-face conversation. Their thoughts and actions can lead to a painful cycle of self-fulfilling prophecies and even self-sabotage. They often seek a dismissive-avoidant partner. Dismissive-avoidant adults desire a high level of independence, often appearing to avoid attachment altogether. They view themselves as self-sufficient, invulnerable to attachment feelings and not needing close relationships. They tend to suppress their feelings, dealing with conflict by distancing themselves from partners of whom they often have a poor opinion. Adults lack the interest of forming close relationships and maintaining emotional closeness with the people around them. They have a great amount of distrust in others but at the same time possess a positive model of self, they would prefer to invest in their own ego skills. Because of their distrust they cannot be convinced that other people have the ability to deliver emotional support. They try to create high levels of self-esteem by investing disproportionately in their abilities or accomplishments. These adults maintain their positive views of self, based on their personal achievements and competence rather than searching for and feeling acceptance from others
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Methods used to study memory They are an ideal animal to use for the study of memory. The assessment of learning and memory in rodents has been employed in scientific research for a long time, and there are many experimental methods used. Generally tests of spatial memory employ maze designs where the rodent must run a maze in order to receive a food reward. Learning can be shown when the rodent reduces its average number of errors or wrong turns. Aversive techniques such as the Morris Water Maze can also be used to study spatial memory. The rat is placed in murky water surrounded by sheer walls containing spatial cues. Learning is shown when the rat swims a more direct route to the obscured platform. Small rodents can also be easily conditioned using taste aversion or odor aversion techniques. Performing neurotoxic lesions in these conditioned rodents is an excellent way to study the neural basis of aversion learning and memory. Psychologists who work with animals assume that the things they learn can be applied to the human brain. Memory is a complex system that relies on interactions between many distinct parts of the brain. In order to fully understand memory, researchers must cumulate evidence from human, animal, and developmental research in order to make broad theories about how memory works. Intraspecies comparisons are key. Rats for example display extremely complex behaviours and most of the structures in their brain parallel those in humans
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Plate (structure) A plate is a structural element which is characterized by two key properties. Firstly, its geometric configuration is a three-dimensional solid whose thickness is very small when compared with other dimensions. Secondly, the effects of the loads that are expected to be applied on it only generate stresses whose resultants are, in practical terms, exclusively normal to the element's thickness. Thin plates are initially flat structural members bounded by two parallel planes, called faces, and a cylindrical surface, called an edge or boundary. The generators of the cylindrical surface are perpendicular to the plane faces. The distance between the plane faces is called the thickness (h) of the plate. It will be assumed that the plate thickness is small compared with other characteristic dimensions of the faces (length, width, diameter, etc.). Geometrically, plates are bounded either by straight or curved boundaries. The static or dynamic loads carried by plates are predominantly perpendicular to the plate faces.
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Filibuster Though the filibuster was criticised by the pro-democracy camp, Lau Kong-wah of the Democratic Alliance for the Betterment and Progress of Hong Kong (DAB) defended their actions, saying "it (a filibuster) is totally acceptable in a parliamentary assembly." Legislators of the Pro-democracy Camp filibustered during a debate about financing the construction of the Guangzhou-Shenzhen-Hong Kong Express Rail Link by raising many questions on very minor issues, delaying the passing of the bill from 18 December 2009 to 16 January 2010. The Legislative Council Building was surrounded by thousands of anti-high-speed rail protesters during the course of the meetings. In 2012, Albert Chan and Wong Yuk-man of People Power submitted a total of 1306 amendments to the Legislative Council (Amendment) Bill, by which the government attempted to forbid lawmakers from participating in by-elections after their resignation. The bill was a response to the so-called 'Five Constituencies Referendum, in which 5 lawmakers from the pro-democracy camp resigned and then joined the by-election, claiming that it would affirm the public's support to push forward the electoral reform. The pro-democracy camp strongly opposed the bill, saying it was seen a deprivation of the citizens' political rights. As a result of the filibuster, the LegCo carried on multiple overnight debates on the amendments
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Strength of materials There are four failure theories: maximum shear stress theory, maximum normal stress theory, maximum strain theory, maximum strain energy theory, and maximum distortion energy theory. Out of these four theories of failure, the maximum normal stress theory is only applicable for brittle materials, and the remaining three theories are applicable for ductile materials. Of the latter three, the distortion energy theory provides most accurate results in majority of the stress conditions. The strain energy theory needs the value of Poisson's ratio of the part material, which is often not readily available. The maximum shear stress theory is conservative. For simple unidirectional normal stresses all theories are equivalent, which means all theories will give the same result. A material's strength is dependent on its microstructure. The engineering processes to which a material is subjected can alter this microstructure. The variety of strengthening mechanisms that alter the strength of a material includes work hardening, solid solution strengthening, precipitation hardening, and grain boundary strengthening and can be quantitatively and qualitatively explained. Strengthening mechanisms are accompanied by the caveat that some other mechanical properties of the material may degenerate in an attempt to make the material stronger. For example, in grain boundary strengthening, although yield strength is maximized with decreasing grain size, ultimately, very small grain sizes make the material brittle
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Gene therapy of the human retina The result showed improvement in photoreceptor structure and function which was detected by ERG (electroretinogram). The result showed improvement of photoreceptor structure and function which was detected by ERG. Also peripherin 2 was detected at the outer segment layer of the retina 2 weeks after injection and therapeutic effects were noted as soon as 3 weeks after injection. A well-defined outer segment containing both peripherin2 and rhodopsin was present 9-month after injection. Since apoptosis can be the cause of photoreceptor death in most of the retinal dystrophies. It has been known that survival factors and antiapoptoic reagents can be an alternative treatment if the mutation is unknown for gene replacement therapy. Some scientists have experimented with treating this issue by injecting substitute trophic factors into the eye. One group of researchers injected the rod derived cone viability factor (RdCVF) protein (encoded for by the Nxnl1 (Txnl6) gene) into the eye of the most commonly occurring dominant RP mutation rat models. This treatment demonstrated success in promoting the survival of cone activity, but the treatment served even more significantly to prevent progression of the disease by increasing the actual function of the cones. Experiments were also carried out to study whether supplying AAV2 vectors with cDNA for glial cell line-derived neurotrophic factor (GDNF) can have an anti-apoptosis effect on the rod cells
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Audience analysis Conversation as well as other qualitative research techniques will allow the communicator to consider the multiple cultural, disciplinary, and institutional contexts of their target audience, producing a valuable audience analysis. David L. Carson of the Rensselaer Polytechnic Institute asserted that technical communicators most often perform their jobs with little or no knowledge about their audience. Carson states that the analysis should include a reader's level of comprehension of the technical vocabulary and motivation, as well as reading level. Indicators of a reader's high level of motivation include high interest in the subject matter, relatively high knowledge of the content, and high personal stakes in mastering the information. Another technique used to conduct an audience analysis is the "bottom-up" approach. Leon de Stadler and Sarah van der Land explore this type of approach in reference to a document produced by an organization that develops different kinds of interventions in the field of HIV/AIDS education. This particular document focused on the use of contraception and targeted the black youth of South Africa. The initial document was created by document designers in the United States who did not base their design on an extensive audience analysis. As a result, the document, which used the informal slang of black South African youth, did not effectively communicate with its target audience
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Microtechnology The term MEMS, for Micro Electro Mechanical Systems, was coined in the 1980s to describe new, sophisticated mechanical systems on a chip, such as micro electric motors, resonators, gears, and so on. Today, the term MEMS in practice is used to refer to any microscopic device with a mechanical function, which can be fabricated in a batch process (for example, an array of microscopic gears fabricated on a microchip would be considered a MEMS device but a tiny laser-machined stent or watch component would not). In Europe, the term MST for Micro System Technology is preferred, and in Japan MEMS are simply referred to as "micromachines". The distinctions in these terms are relatively minor and are often used interchangeably. Though MEMS processes are generally classified into a number of categories – such as surface machining, bulk machining, LIGA, and EFAB – there are indeed thousands of different MEMS processes. Some produce fairly simple geometries, while others offer more complex 3-D geometries and more versatility. A company making accelerometers for airbags would need a completely different design and process to produce an accelerometer for inertial navigation. Changing from an accelerometer to another inertial device such as a gyroscope requires an even greater change in design and process, and most likely a completely different fabrication facility and engineering team
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Dehumidifier This is a very energy efficient technology and equally efficient in all temperatures. Most portable dehumidifiers are equipped with a condensate collection receptacle, typically with a float sensor that detects when the collection vessel is full, to shut off the dehumidifier and prevent an overflow of collected water. In a warm humid environment, these buckets will generally fill with water in 8–12 hours, and may need to be manually emptied and replaced several times per day to ensure continued operation. Many portable dehumidifiers can also be adapted to connect the condensate drip output directly to a drain via a hose. Some dehumidifier models can tie into plumbing drains or use a built-in water pump to empty themselves as they collect moisture. Alternatively, a separate condensate pump may be used to move collected water to a disposal location when gravity drainage is not possible. Central air conditioning units typically need to be connected to a drain, because the quantity of condensate water generated by such systems can be quite large over time. If the condensate water is directed into the sewer system, it should be suitably trapped. Otherwise, back pressure can allow smells or sewer gases to enter the building. The condensate should not be directed into a septic system of a house, because large central air conditioning systems discharge water that does not need to be treated by septic systems
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Quantum social science In a 1997 lecture on "Diplomacy in the Information Age", former US Secretary of State George P. Shultz credits the physicist Sidney Drell for coining the term "quantum diplomacy" to describe how diplomats need to account for uncertainty and the fact that "the process of observation itself is a cause of change". In a 2011 paper, James Der Derian proposed quantum diplomacy as a way to understand the entanglements brought about by a globalized media and a multiplicity of actors operating at different levels. These ideas have been a theme of Der Derian's annual Q2-Symposium since 2014. In a 2018 address to the Trilateral Commission, Danah Zohar argued that a mechanistic worldview has led to problems from inequality to climate change, and that we need to shift to a quantum perspective which incorporates effects such as uncertainty and entanglement. While Wendt's 2015 book "Quantum Mind and Social Science" does not focus on political science, it does discuss the applicability of quantum theory to social systems in general, and its publication led to a great deal of analysis and discussion on this topic. Other related areas where quantum ideas are seeing applications include quantum game theory, quantum decision theory, quantum finance and quantum economics. In a 2019 article for the Bretton Woods Committee, Andrew Sheng wrote that "A quantum paradigm of finance and the economy is slowly emerging, and its nonlinear, complex nature may help the design of a future global economy and financial architecture
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Ethidium homodimer assay An ethidium homodimer assay can be used to detect dead or dying cells. Ethidium homodimer is a membrane-impermeable fluorescent dye which binds to DNA. After a cell sample has been stained with ethidium homodimer, the dead cells may be viewed and counted under a UV-light microscope. When cells die, the plasma membranes of those cells becomes disrupted. Because of this, ethidium homodimer may enter those cells and bind to DNA within those cells. Because live cells don't have a compromised membrane, the ethidium homodimer can't enter. One reason for doing an ethidium homodimer assay instead of using a TUNEL assay to measure cell death is that ethidium homodimer stains all of the dead or dying cells, while TUNEL only stains cells that have undergone programmed cell death.
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Surge protector The terms "surge protection device" ("SPD") and "transient voltage surge suppressor" ("TVSS") are used to describe electrical devices typically installed in power distribution panels, process control systems, communications systems, and other heavy-duty industrial systems, for the purpose of protecting against electrical surges and spikes, including those caused by lightning. Scaled-down versions of these devices are sometimes installed in residential service entrance electrical panels, to protect equipment in a household from similar hazards. Many power strips have basic surge protection built in; these are typically clearly labeled as such. However, in unregulated countries there are power strips labelled as "surge" or "spike" protectors that only have a capacitor or RFI circuit (or nothing) that do "not" provide true (or any) spike protection. These are some of the most prominently featured specifications which define a surge protector for AC mains, as well as for some data communications protection applications. Also known as the let-through voltage, this specifies what spike voltage will cause the protective components inside a surge protector to short or clamp. A lower clamping voltage indicates better protection, but can sometimes result in a shorter life expectancy for the overall protective system. The lowest three levels of protection defined in the UL rating are 330 V, 400 V and 500 V. The standard let-through voltage for 120 V AC devices is 330 volts
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Coral reef The less water movement, the better the chance for fertilization. Ideal timing occurs in the spring. Release of eggs or planula usually occurs at night, and is sometimes in phase with the lunar cycle (three to six days after a full moon). The period from release to settlement lasts only a few days, but some planulae can survive afloat for several weeks. They are vulnerable to predation and environmental conditions. The lucky few planulae that successfully attach to substrate then compete for food and space. Corals are the most prodigious reef-builders. However many other organisms living in the reef community contribute skeletal calcium carbonate in the same manner as corals. These include coralline algae and some sponges. Reefs are always built by the combined efforts of these different phyla, with different organisms leading reef-building in different geological periods. Coralline algae are important contributors to reef structure. Although their mineral deposition-rates are much slower than corals, they are more tolerant of rough wave-action, and so help to create a protective crust over those parts of the reef subjected to the greatest forces by waves, such as the reef front facing the open ocean. They also strengthen the reef structure by depositing limestone in sheets over the reef surface. "Sclerosponge" is the descriptive name for all "Porifera" that build reefs
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Municipal wireless network Verge Wireless built networks for Baton Rouge, New Orleans, and other areas. Some applications include wireless security cameras, police mug shot software, and location-based advertising. In 2007, some companies with existing cell sites offered high-speed wireless services where the laptop owner purchased a PC card or adapter based on EV-DO cellular data receivers or WiMAX rather than 802.11b/g. A few high-end laptops at that time featured built-in support for these newer protocols. WiMAX is designed to implement a metropolitan area network (MAN) while 802.11 is designed to implement a wireless local area network (LAN). However, the use of cellular networks is expensive for the consumers, as they are often on limited data plans. In the 2010s larger cities embraced the smart city concept to tackle problems such as traffic congestion, crime, encouraging economic growth, responding to the effects of climate change and improving the delivery of city services. However, by 2018 it has become clear that the private sector could not be relied upon to build up city-wide wireless networks to meet the smart city objectives of municipal governments and public utility providers. The construction of municipal wireless networks is a significant part of their lifetime costs. Usually, a private firm works with local government to construct a network and operate it. Financing is usually shared by both the private firm and the municipal government
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Sleeper wall A sleeper wall is a short wall used to support floor joists, beam and block or hollowcore slabs at ground floor. It is constructed in this fashion when a suspended slab is required due to bearing conditions or ground water presence. Essentially it is a wall in the way that it is constructed but a sleeper in the way that it functions. Normal construction is of brick or concrete block either in stretcher bond or header stretcher bond
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Maria Pia Bridge Gustave Eiffel's design proposal, priced at 965,000 French francs, was the least expensive of the four designs considered, around two thirds of the cost of the nearest competitor. Since the company was relatively inexperienced, a commission was appointed to report on their suitability to undertake the work. Their report was favorable, although it did emphasise the difficulty of the project: Responsibility for the actual design is difficult to attribute, but it is probable that a large part was played by Théophile Seyrig, Eiffel's business partner, who presented a paper on the bridge to the Société des Ingénieurs Civils in 1878. Eiffel, in his account of the bridge, which accompanied the 1:50 scale model exhibited at the 1878 World's Fair, credited Seyrig, along with Henry de Dion, with work on the calculations and drawings. Construction started on 5 January 1876, and work on the abutments, piers and approach decking was complete by September. Work then paused due to winter flooding, and the erection of the central arch span was not re-started until March 1877. Construction was completed on 1 October 1877. By 28 October 1877, the platform was mounted and concluded, with the work on the bridge executed using a complement of 150 workers finishing on 30 October 1878. Tests were performed between 1 and 2 November, leading to the 4 November inauguration by King D. Louis I and Queen Maria Pia of Savoy (the eponym of the bridge)
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Software remastering The snapshot also serves as an essentially complete and convenient backup of the installation. The examples in this section show some historical and operational aspects of the software remastering as it has occurred with Microsoft Windows. 98lite is a remastering tool for Windows 95, Windows 98 and Windows Me without Internet Explorer, written by Shane Brooks. It was written in response to Microsoft's claim, in antitrust proceedings, that IE is integrated into Windows and cannot be removed without breaking other features. 98lite was created in 1998 after the original release of Windows 98, out of necessity, since at the time Brooks had a slower laptop computer that ran the Windows 95 operating system fine but Windows 98 was simply too slow. Brooks liked the stability Windows 98 offered as well as some of the new features but had no need for the Internet Explorer browser. The original 98lite was a simple DOS based installer that ran before the Windows 98 installation, this installer made modifications to a fresh installation of Windows preventing the installation of Internet Explorer and the Active Desktop. Installation of the first release of 98lite required the user to extract certain files from a Windows 95 disk as 98lite uses the Windows 95 shell
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Methyltransferase Inhibition of overall DNA methyltransferase activity has been proposed as a treatment option, but DNMT inhibitors, analogs of their cytosine substrates, have been found to be highly toxic due to their similarity to cytosine (see right); this similarity to the nucleotide causes the inhibitor to be incorporated into DNA translation, causing non-functioning DNA to be synthesized. A methylase which alters the ribosomal RNA binding site of the antibiotic linezolid causes cross-resistance to other antibiotics that act on the ribosomal RNA. Plasmid vectors capable of transmitting this gene are a cause of potentially dangerous cross resistance. Examples of methyltransferase enzymes relevant to disease: Recent work has revealed the methyltransferases involved in methylation of naturally occurring anticancer agents to use S-Adenosyl methionine (SAM) analogs that carry alternative alkyl groups as a replacement for methyl. The development of the facile chemoenzymatic platform to generate and utilize differentially alkylated SAM analogs in the context of drug discovery and drug development is known as alkylrandomization. In human cells, it was found that m5C was associated with abnormal tumor cells in cancer. The role and potential application of m5C includes to balance the impaired DNA in cancer both hypermethylation and hypomethylation
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Chaplygin's equation Similarly the velocity potential is replaced by a new function (Legendre transformation) such then its differential is formula_21, therefore Introducing another coordinate transformation for the independent variables from formula_4 to formula_24 according to the relation formula_25 and formula_26, where formula_27 is the magnitude of the velocity vector and formula_28 is the angle that the velocity vector makes with the formula_29-axis, the dependent variables become The continuity equation in the new coordinates become For isentropic flow, formula_32, where formula_33 is the speed of sound. Using the Bernoulli's equation we find where formula_2. Hence, we have
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Body jewelry sizes express the thickness of an item of body jewelry, using one of several possible systems. Items of body piercing jewelry have an important common factor: the diameter of the part of the item of jewelry where it will rest in the piercing site. With the wearing of European-traditional kinds of earrings, that thickness is not an issue, because jewelry is made to use only thin wire for support, and the wearer need only have a narrow piercing hole to accommodate it. But with body jewelry, there is a wide variety of possible sizes, and wearers generally want jewelry that is the same size as their piercing site. Some wearers want increasingly larger sizes to deliberately stretch the hole. So that wearers can choose the size they want, there are standards for body jewelry sizes, used by jewelry makers and sellers. Generally, the system of gauge-and-inches is used: In gauge notation, jewelry less than ″ thick is "typically" measured in a system originally devised for measuring wire thickness. A gauge number denotes a thickness on a standardized scale which, for most purposes, starts at 20g (0.812 mm thick— often used for the posts for nose studs), and increases in thickness (as the gauge number "decreases") to 0g, then 00g, and rarely goes any further as these thicknesses come closer and closer to ″. From there, sizes of ″ and thicker are always specified in fractions of an inch
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E-meter The is an electronic device for displaying the electrodermal activity (EDA) of a human being. The device is used for auditing in Scientology and divergent groups. The efficacy and legitimacy of Scientology's use of the has been subject to extensive debate and litigation and in accordance with a federal court order, the Church of Scientology now publishes disclaimers in its books and publications declaring that the "by itself does nothing" and that it is used specifically for spiritual purposes. Such devices have been used as a research tool in many human studies, and as one of several components of the Leonarde Keeler's polygraph (lie detector) system, which has been widely criticized as ineffective or pseudoscientific by legal experts and psychologists. Electrodermal activity (EDA) is the changing electrical charges observed on the surface of the skin. EDA meters were first developed in 1889 in Russia, and psychotherapists began using them as tools for therapy in the 1900s. Volney Mathison built an EDA meter based on a Wheatstone bridge, a vacuum tube amplifier, and a large moving-coil meter that projected an image of the needle on the wall. He patented his device in 1954 as an "electropsychometer" or E-meter, and it came to be known as the "Mathison Electropsychometer". In Mathison's words, the "has a needle that swings back and forth across a scale when a patient holds on to two electrical contacts"
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Super Bloch oscillations On top of the Bloch oscillation, the motion shows a much larger oscillation in position space that extends over hundreds of lattice sites. Those directly correspond to the motion of normal Bloch oscillations, just rescaled in space and time. A quantum mechanical description of the rescaling can be found here. An experimental realization is demonstrated in these. A theoretical analysis of the properties of Super-Bloch Oscillations, including dependence on the phase of the driving field is found here.
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Parge coat A parge coat is a thin coat of a cementitious or polymeric mortar applied to concrete or masonry for refinement of the surface. Pargeting is a more involved process, involving designs in relief created in the surface. Parging is usually applied with a trowel and pressed into the existing surface. The intent is to create a contiguous surface by filling imperfections such as surface air voids created by bughole-induced outgassing, to level a surface for aesthetic reasons, or to prep a surface for topcoating with an additional form of protective coating. Parging is a low-cost alternative to repointing, providing structural cohesiveness to masonry walls whose mortar has begun to fail. Parge coating can also be used to create air tightness for apartments.
https://en.wikipedia.org/wiki?curid=8903435
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Pitch drop experiment Since mid-March 2018, the live feed was interrupted due to technical problems in the experiment's webpage. Timeline for the University of Queensland experiment: The pitch drop experiment at Trinity College Dublin in Ireland was started in October 1944 by an unknown colleague of the Nobel Prize winner Ernest Walton while he was in the physics department of Trinity College. This experiment, like the one at Queensland University, was set up to demonstrate the high viscosity of pitch. This physics experiment sat on a shelf in a lecture hall at Trinity College unmonitored for decades as it dripped a number of times from the funnel to the receiving jar below, also gathering layers of dust. In April 2013, about a decade after the previous pitch drop, physicists at Trinity College noticed that another drip was forming. They moved the experiment to a table to monitor and record the falling drip with a webcam, allowing all present to watch. The pitch dripped around 5:00pm on 11 July 2013, marking the first time that a pitch drop was successfully recorded on camera. Based on the results from this experiment, the Trinity College physicists estimated that the viscosity of the pitch is about two million times that of honey, or about 20 billion times the viscosity of water. It is reported that a pitch drop experiment has been recently rediscovered at Aberystwyth University in Wales. Dating from 1914, it predates the Queensland experiment by 13 years
https://en.wikipedia.org/wiki?curid=250107
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Ninety One plc is an asset management business. It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index. The company was formed as Investec Asset Management in 1991. It changed its name to Ninety One in spring 2020: the new name is in recognition of the brand's heritage - it was in 1991 that the investment firm was started in South Africa. It was demerged from Investec in March 2020. It had been envisaged that 10% of the stock would be offered to the public but Investec decided to retain 25% (rather than just 15% as originally planned) because of market conditions.
https://en.wikipedia.org/wiki?curid=63036717
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Automatic meter reading The resolution also called for AMI business case analysis to identify cost-effective deployment strategies, endorsed timely cost recovery for prudently incurred AMI expenditures and made additional recommendations on rate making and tax treatment of such investments. Advanced metering systems can provide benefits for utilities, retail providers and customers. Benefits will be recognized by the utilities with increased efficiencies, outage detection, tamper notification and reduced labor cost as a result of automating reads, connections and disconnects. Retail providers will be able to offer new innovative products in addition to customizing packages for their customers. In addition, with the meter data being readily available, more flexible billing cycles would be available to their customers instead of following the standard utility read cycles. With timely usage information available to the customer, benefits will be seen through opportunities to manage their energy consumption and change from one REP to another with actual meter data. Because of these benefits, many utilities are moving towards implementing some types of AMR solutions. In many cases, smart metering is required by law (e.g. Pennsylvania's Act 129 (2008)). The benefits of smart metering for the utility. The benefits of smart metering for the customer. Construction practices, weather, and the need for information drive utilities in different parts of the world towards AMR at different rates
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Hydrogen storage Using the existing natural gas system for hydrogen, Fuel cell maker Hydrogenics and natural gas distributor Enbridge have teamed up to develop such a power to gas system in Canada. Pipeline storage of hydrogen where a natural gas network is used for the storage of hydrogen. Before switching to natural gas, the German gas networks were operated using towngas, which for the most part (60-65%) consisted of hydrogen. The storage capacity of the German natural gas network is more than 200,000 GW·h which is enough for several months of energy requirement. By comparison, the capacity of all German pumped storage power plants amounts to only about 40 GW·h. The transport of energy through a gas network is done with much less loss (<0.1%) than in a power network (8%). The use of the existing natural gas pipelines for hydrogen was studied by NaturalHy Targets were set by the FreedomCAR Partnership in January 2002 between the United States Council for Automotive Research (USCAR) and U.S. DOE (Targets assume a 5-kg H storage system). The 2005 targets were not reached in 2005. The targets were revised in 2009 to reflect new data on system efficiencies obtained from fleets of test cars. The ultimate goal for volumetric storage is still above the theoretical density of liquid hydrogen. It is important to note that these targets are for the hydrogen storage system, not the hydrogen storage material
https://en.wikipedia.org/wiki?curid=5382986
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Chena Pump House The Chena Pump House, also known just as the Pump House Restaurant, is a restaurant at 796 Chena Pump Road in Fairbanks, Alaska. The restaurant is located in the shell of a 1933 pumping station established by the Fairbanks Exploration Company, Alaska's largest gold mining operator at the time. The pump house was used to provide water to dredges operating on Cripple Creek in the Ester area. The building was abandoned by the company in 1958, and was enlarged and converted into a restaurant in 1978. It was listed on the National Register of Historic Places in 1982.
https://en.wikipedia.org/wiki?curid=44932495
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Micromachinery Micromachines are mechanical objects that are fabricated in the same general manner as integrated circuits. They are generally considered to be between 100 nanometres to 100 micrometres in size, though that is debatable. The applications of micromachines include accelerometers that detect when a car has hit an object and trigger an airbag. Complex systems of gears and levers are another application. The fabrication of these devices is usually done by two techniques, surface micromachining and bulk micromachining. To do bulk micromachining, the region needed is highly doped with boron and the unwanted silicon is etched in liquid silicon etches. This technique is termed an etchstop as the doping of boron produces an unetchable layer/pattern. Most micromachines act as transducers; in other words, they are either sensors or actuators. Sensors convert information from the environment into interpretable electrical signals. One example of a micromachine sensor is a resonant chemical sensor. A lightly damped mechanical object vibrates much more at one frequency than any other, and this frequency is called its resonance frequency. A chemical sensor is coated with a special polymer that attracts certain molecules, such as those found in anthrax, and when those molecules attach to the sensor, its mass increases. The increased mass alters the resonance frequency of the mechanical object, which is detected with circuitry. Actuators convert electrical signals and energy into motion of some kind
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Sustainable engineering For example, even if we properly place warning signs about these hazardous wastes, we do not know if the English language will be understood. All four goals of green engineering mentioned above are supported by a long-term, life cycle point of view. A life cycle analysis is a holistic approach to consider the entirety of a product, process or activity, encompassing raw materials, manufacturing, transportation, distribution, use, maintenance, recycling, and final disposal. In other words, assessing its life cycle should yield a complete picture of the product. The first step in a life cycle assessment is to gather data on the flow of a material through an identifiable society. Once the quantities of various components of such a flow are known, the important functions and impacts of each step in the production, manufacture, use, and recovery/disposal are estimated. Thus, in sustainable design, engineers must optimize for variables that give the best performance in temporal frames. In 2013, the average annual electricity consumption for a U.S. residential utility customer was 10,908 kilowatt hours (kWh), an average of 909 kWh per month. Louisiana had the highest annual consumption at 15,270 kWh, and Hawaii had the lowest at 6,176 kWh. Residential sector itself uses 18% of the total energy generated and therefore, incorporating sustainable construction practices there can be significant reduction in this number. Basic Sustainable construction practices include :
https://en.wikipedia.org/wiki?curid=18624923
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ACS Synthetic Biology is a peer-reviewed scientific journal published by the American Chemical Society. It began publishing accepted articles in the Fall of 2011, with the first full monthly issue published in January 2012. It covers all aspects of synthetic biology, including molecular, systems, and synthetic research. The editor-in-chief is Christopher Voigt (Massachusetts Institute of Technology). The journal publishes
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Zune Pad The Zune Pad, which is a squircle, is the primary control mechanism for Zune 4, 8, 16, 80 and 120. The pad lets users of this device scroll through a long list of songs with a few flicks of the finger, then press the button to select tracks or change the volume. It was designed by Microsoft for the release of the second generation Zune. The is about 24 mm in diameter and resembles a square like figure. It comprises a touch-sensitive button with simulated up, down, left, right and center navigational "button" response. It combines this touch interface with standard 5-way D-pad functionality. The Pad is capable of detecting movements in all directions. The user can press the top, bottom, left, right and center of the pad inward to navigate through lists or select an item or use the touch interface to move up, down, left and right. Selection is always done with a center click. The user can touch and slide to move up or down on the screen. The motion of the select box on the screen is viewport-controlled where moving the finger up moves the view of the content up. This is unlike direct content manipulation interfaces, where moving the finger up moves the content up, equivalent to moving the viewport down the list. The allows the user to coast after flicking the list and to accelerate through the list with repeated flicks, unlike direct content manipulation interfaces in which a touch immediately grabs and stops the onscreen content
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Broadcast signal intrusion On August 26, 2016, 2 Required Weekly Tests were received in cable system in Milwaukee's Roku cable for the New York City area and New Jersey. On September 9, 2016, 3 Required Weekly Tests for the same states. 3 days later, more states were added, including all of Kentucky, Ohio, and Tennessee. These areas include Columbus. The Evansville and Indianapolis areas including the state of Indiana were added 2 days later on September 14. A week later on September 21, more than 20 Required Weekly Tests were sent in many added states between 12:21 AM until 2:56 AM. All of the states were also included, including the states of Ohio (including the cities of Columbus from receivers 1 and 3, and Cincinnati), Kentucky (a couple of them were sent from the cities of Springfield, Bowling Green, Harrodsburg, Georgetown, and Mount Sterling while the rest is unknown in Kentucky), New York (a couple were sent from the city of Rome; and a few from the New York City area), Virginia (Newport News area), North Carolina (sent from Elizabeth City), Michigan (Detroit Area), and Texas (sent from the City of Grapevine). On September 7, 2012, the Disney Channel once again was interrupted on the Dish Network, replacing 6 minutes of "Lilo & Stitch" with a portion of a hardcore pornographic movie. On March 11, 2016, private satellite dish owners in Israel watching "HaAh HaGadol" (the Israeli version of "Big Brother") on Channel 2 had their show interrupted by propaganda videos from Hamas
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Vitamin C Until quite late in the disease the damage is reversible, as healthy collagen replaces the defective collagen with vitamin C repletion. Treatment can be orally or by intramuscular or intravenous injection. Scurvy was known to Hippocrates in the classical era. The disease was shown to be prevented by citrus fruit in an early controlled trial by a Royal Navy surgeon, James Lind, in 1747, and from 1796 lemon juice was issued to all Royal Navy crewmen. Research on vitamin C in the common cold has been divided into effects on prevention, duration, and severity. A Cochrane review which looked at at least 200 mg/day concluded that vitamin C taken on a regular basis was not effective in prevention of the common cold. Restricting analysis to trials that used at least 1000 mg/day also saw no prevention benefit. However, taking vitamin C on a regular basis did reduce the average duration by 8% in adults and 14% in children, and also reduced severity of colds. A subsequent meta-analysis in children found that vitamin C approached statistical significance for prevention and reduced the duration of upper respiratory tract infections. A subset of trials in adults reported that supplementation reduced the incidence of colds by half in marathon runners, skiers, or soldiers in subarctic conditions. Another subset of trials looked at therapeutic use, meaning that vitamin C was not started unless the people started to feel the beginnings of a cold. In these, vitamin C did not impact duration or severity
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Electromagnetic lock , Canada, and throughout Asia were later established to create additional product offerings for the direct-pull electromagnetic lock. The principle behind an electromagnetic lock is the use of electromagnetism to lock a door when energized. The holding force should be collinear with the load, and the lock and armature plate should be face-to-face to achieve optimal operation. The magnetic lock relies upon some of the basic concepts of electromagnetism. Essentially it consists of an electromagnet attracting a conductor with a force large enough to prevent the door from being opened. In a more detailed examination, the device makes use of the fact that a current through one or more loops of wire (known as a solenoid) produces a magnetic field. This works in free space, but if the solenoid is wrapped around a ferromagnetic core such as soft iron the effect of the field is greatly amplified. This is because the internal magnetic domains of the material align with each other to greatly enhance the magnetic flux density. Using the Biot–Savart law, it can be shown that the magnetic flux density formula_1 induced by a solenoid of effective length formula_2 with a current formula_3 through formula_4 loops is given by the equation: The force formula_6 between the electromagnet and the armature plate with surface area formula_7 exposed to the electromagnet is given by the equation: In both equations, formula_9 represents the permeability of free space and formula_10 the relative permeability of the core
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Direct-sequence spread spectrum This effect is the basis for the code division multiple access (CDMA) property of DSSS, which allows multiple transmitters to share the same channel within the limits of the cross-correlation properties of their spreading sequences.
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Shrink–swell capacity However, lack of these cracks does not mean a soil is not expansive. Many methods may be employed to mitigate or prevent the damage caused by expansive soils. When it comes to foundations, one solution is to extend building foundations to a depth where they are below the zone of water content fluctuation. This supports them when the soil shrinks, and anchors them when the soil swells. Another solution is to remove the pre-existing expansive soil and replace it with a non-expansive soil, but if the depth of the expansive soil is too deep, this option is very expensive. Maintaining a constant soil moisture is another solution, which sometimes may be achieved by allowing rainwater to properly drain away from the property, fixing areas around structures that have poor drainage qualities, fixing pipe leaks, avoiding over-watering nearby plants, and by planting trees some distance away from any structure. Yet another solution is a process called soil stabilization, in which additional materials are added to the soil to limit its ability to shrink and swell. Materials for stabilization include cement, resins, fly ash, lime, pozzolana, or lime-pozzolana mixture, depending on the site conditions and the project goals.
https://en.wikipedia.org/wiki?curid=18309403
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Gear A "cage gear", also called a "lantern gear" or "lantern pinion", has cylindrical rods for teeth, parallel to the axle and arranged in a circle around it, much as the bars on a round bird cage or lantern. The assembly is held together by disks at each end, into which the tooth rods and axle are set. Cage gears are more efficient than solid pinions, and dirt can fall through the rods rather than becoming trapped and increasing wear. They can be constructed with very simple tools as the teeth are not formed by cutting or milling, but rather by drilling holes and inserting rods. Sometimes used in clocks, the "cage gear" should always be driven by a gearwheel, not used as the driver. The "cage gear" was not initially favoured by conservative clock makers. It became popular in turret clocks where dirty working conditions were most commonplace. Domestic American clock movements often used them. All cogs of each gear component of magnetic gears act as a constant magnet with periodic alternation of opposite magnetic poles on mating surfaces. components are mounted with a backlash capability similar to other mechanical gearings. Although they cannot exert as much force as a traditional gear, such gears work without touching and so are immune to wear, have very low noise and can slip without damage making them very reliable. They can be used in configurations that are not possible for gears that must be physically touching and can operate with a non-metallic barrier completely separating the driving force from the load
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Conversation pit A conversation pit is an architectural feature that incorporates built-in seating into a depressed section of flooring within a larger room. This area often has a table in the center as well. The seats typically face each other in a centrally focused fashion, bringing the occupants closer together than free-standing tables and chairs normally would. In residential design this proximity facilitates comfortable human conversation, dinner parties, and table top games. Their disadvantages include accidental falls and uncomfortable interactions with those standing above in the main room. The conversation pit was popular from the 1950s to the 1970s, seen across Europe as well as North America. Modernist architects Eero Saarinen and Alexander Girard used a conversation pit as the centerpiece of the influential Miller House (1958) in Columbus, Indiana, one of the earliest widely publicized applications of the concept. A brilliant red conversation pit (since covered, but recently restored) was later incorporated by Saarinen into the 1962 TWA Flight Center at John F. Kennedy International Airport in New York. Other influential residential projects include the 1955 Cohen House in Sarasota, Florida, by architect Paul Rudolph, for whom the conversation pit became a signature element, and many of Bruce Goff's houses beginning in the 1920s, including the Adah Robinson house in Tulsa, Oklahoma and the 1965 Nicol House in Kansas City, Missouri
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Plasterwork A first coat or rendering of Portland cement and sand, in the proportion of one to three, is laid on about an inch thick; then follows the color coat, sometimes put on in patches of different tints as required for the finished design. When this coat is nearly dry, it is finished with a smooth-skimming, 1/12 to 1/8 inches thick, of Parian, selenitic or other fine cement or lime, only as much as can be finished in one day being laid on. Then by pouncing through the pricked cartoon, the design is transferred to the plastered surface. Broad spaces of background are now exposed by removing the finishing coat, thus revealing the colored plaster beneath, and following this the outlines of the rest of the design are scratched with an iron knife through the outer skimming to the underlying tinted surface. Sometimes the coats are in three different colors, such as brown for the first, red for the second, and white or grey for the final coat. The pigments used for this work include Indian red, Turkey red, Antwerp blue, German blue, umber, ochre, purple brown, bone black or oxide of manganese for black. Combinations of these colors are made to produce any desired tone. Plasters are applied in successive coats or layers on walls or lathing and gains its name from the number of these coats
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Nucleosome A recent advance in the production of nucleosome core particles with enhanced stability involves site-specific disulfide crosslinks. Two different crosslinks can be introduced into the nucleosome core particle. A first one crosslinks the two copies of H2A via an introduced cysteine (N38C) resulting in histone octamer which is stable against H2A/H2B dimer loss during nucleosome reconstitution. A second crosslink can be introduced between the H3 N-terminal histone tail and the nucleosome DNA ends via an incorporated convertible nucleotide. The DNA-histone octamer crosslink stabilizes the nucleosome core particle against DNA dissociation at very low particle concentrations and at elevated salt concentrations. Nucleosomes are the basic packing unit of DNA built from histone proteins around which DNA is coiled. They serve as a scaffold for formation of higher order chromatin structure as well as for a layer of regulatory control of gene expression. Nucleosomes are quickly assembled onto newly synthesized DNA behind the replication fork. Histones H3 and H4 from disassembled old nucleosomes are kept in the vicinity and randomly distributed on the newly synthesized DNA. They are assembled by the chromatin assembly factor-1 (CAF-1) complex, which consists of three subunits (p150, p60, and p48). Newly synthesized H3 and H4 are assembled by the replication coupling assembly factor (RCAF). RCAF contains the subunit Asf1, which binds to newly synthesized H3 and H4 proteins
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Conference on Information and Knowledge Management The ACM (CIKM, pronounced ) is an annual computer science research conference dedicated to information management (IM) and knowledge management (KM). Since the first event in 1992, the conference has evolved into one of the major forums for research on database management, information retrieval, and knowledge management. The conference is noted for its interdisciplinarity, as it brings together communities that otherwise often publish at separate venues. Recent editions have attracted well beyond 500 participants. In addition to the main research program, the conference also features a number of workshops, tutorials, and industry presentations. For many years, the conference was held in the USA. Since 2005, venues in other countries have been selected as well. Locations include:
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Anarchism However, the 1960s witnessed a revival of anarchism likely caused by a perceived failure of Marxism–Leninism and tensions built by the Cold War. During this time, anarchism took root in other movements critical to both the state and capitalism such as the anti-nuclear, environmental and pacifist movements, the New Left, and the counterculture of the 1960s. became associated with punk subculture as exemplified by bands such as Crass and the Sex Pistols, and the established feminist tendencies of anarcha-feminism returned with vigour during the second wave of feminism. Around the turn of the 21st century, anarchism grew in popularity and influence within anti-war, anti-capitalist and anti-globalisation movements. Anarchists became known for their involvement in protests against the World Trade Organization, Group of Eight and World Economic Forum. During the protests, "ad hoc" leaderless anonymous cadres known as black blocs engaged in rioting, property destruction and violent confrontations with the police. Other organisational tactics pioneered in this time include security culture, affinity groups and the use of decentralised technologies such as the internet. A significant event of this period was the confrontations at the WTO conference in Seattle in 1999. Anarchist ideas have been influential in the development of the Zapatistas in Mexico and the Democratic Federation of Northern Syria, more commonly known as Rojava, a "de facto" autonomous region in northern Syria
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Belgo Building The () is a six-storey building in the Quartier des spectacles district of Montreal, Quebec, Canada. It houses 27 art galleries as well as artist workshops and dance studios. It is located at 372 Saint Catherine Street West. The was designed in 1912 by architects Finley & Spence and completed in 1913. The exterior materials are a combination of yellow brick, Indiana limestone and Montreal greystone. The building was altered in 1958 by architect F. David Mathias, who renovated the main entrance in polished green granite. The building originally housed a luxury department store known as Scroggie's. It was later sold to an American company and renamed Almy's, after which the upper floors were leased to companies in the garment industry. Almy's closed in 1922, after which the entire building was used by the garment industry. In the 1980s artists began renting out space in the building, while garment business were moving out, as the garment district shifted north to Mile End and later Ahuntsic. Today, the building is home to the largest concentration of contemporary art galleries in Canada.
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Performance gap After that, other authors have shown an interest in the uncertainties that are present in building design; Ramallo-González classified uncertainties in building design/construction in three different groups: The type 1 from this grouping, have been divided here into two main groups: one concerning the uncertainty due to climate change; and the other concerning uncertainties due to the use of synthetic weather data files. Concerning the uncertainties due to climate change: buildings have long life spans, for example, in England and Wales, around 40% of the office blocks existing in 2004 were built before 1940 (30% if considered by floor area). and, 38.9% of English dwellings in 2007 were built before 1944. This long life span makes buildings likely to operate with climates that might change due to global warming. De Wilde and Coley showed how important is to design buildings that take into consideration climate change and that are able to perform well in future weathers. Concerning the uncertainties due to the use of synthetic weather data files: Wang et al. showed the impact that uncertainties in weather data (among others) may cause in energy demand calculations. The deviation in calculated energy use due to variability in the weather data were found to be different in different locations from a range of (-0.5% – 3%) in San Francisco to a range of (-4% to 6%) in Washington D.C. The ranges were calculated using TMY as the reference
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Yury Gogotsi Drexel Nanomaterials Institute); 2002—2007 — Associate Dean of the College of Engineering for Special Projects; 2002—present — Professor of Chemistry (courtesy appointment); 2001—present — Professor of Mechanical Engineering and Mechanics (courtesy appointment); 2000—present — Professor of Materials Science and Engineering; 2001—2003 — Adjunct Professor of Mechanical Engineering ; 1999—2000 — Associate Professor of Mechanical Engineering with tenure; 1999—2000 — Assistant Director, UIC Research Resources Center; 1996—1999 — Assistant Professor of Mechanical Engineering University of Tübingen, Germany 1995—1996 — Research Scientist 1993—1995 — Research scientist at the Center for Materials Research, NATO/Norwegian Research Council Fellowship 1992—1993 — Research scientist, Japan Society for the Promotion of Science (JSPS) Fellowship 1990—1992 — Research scientist, Alexander von Humboldt Fellowship 1986—1990 — Research scientist Professor has received many awards and recognitions for his research accomplishments, some of which include: 2017 — Energy Storage Materials Award; 2017 — Honorary Doctorate from Frantsevich Institute for Problems of Materials Science, National Academy of Science of Ukraine; 2016 — Honorary professorship in Jilin University; 2016 — Honorary professorship in Beijing University of Chemical Technology; 2016 — Highly Cited Researcher (Thomson-Reuters); 2016 — Nano Energy Award 2015 — Highly Cited Researcher (Thomson-Reuters); 2015 — Has been admitted as a Fellow of the Royal Society of Chemis
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Passive solar building design Overhangs are used to block direct sunlight in the summer, and allow it in the winter, and heat reflecting blinds are inserted between the thermal wall and the glazing to limit heat build-up in the summer months. Another study analyzed double-green skin facade (DGSF) on the outside of high rise buildings in Hong Kong. Such a green facade, or vegetation covering the outer walls, can combat the usage of air conditioning greatly - as much as 80%, as discovered by the researchers. In more temperate climates, strategies such as glazing, adjustment of window-to-wall ratio, sun shading and roof strategies can offer considerable energy savings, in the 30% to 60% range.
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History of manufactured fuel gases Originally, the waste of the purifier house was flushed into a nearby body of water, such as a river or a canal. However, after fish kills, the nauseating way it made the rivers stink, and the truly horrendous stench caused by exposure of residuals if the river was running low, the public clamoured for better means of disposal. Thus it was piled into heaps for disposal. Some enterprising gas entrepreneurs tried to sell it as a weed-killer, but most people wanted nothing to do with it, and generally, it was regarded as waste which was both smelly and poisonous, and gas-works could do little with, except bury. But this was not the end of the "blue billy", for after burying it, rain would often fall upon its burial site, and leach the poison and stench from the buried waste, which could drain into fields or streams. Following countless fiascoes with "blue billy" contaminating the environment, a furious public, aided by courts, juries, judges, and masters in chancery, were often very willing to demand that the gas-works seek other methods of purification – and even pay for the damages caused by their old methods of purification. This led to the development of the "dry lime" purification process, which was less effective than the "wet lime" process, but had less toxic consequences. Still, it was quite noxious. Slaked lime (calcium hydroxide) was placed in thick layers on trays which were then inserted into a square or cylinder-shaped purifier tower which gas was then passed through, from the bottom to the top
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Body jewelry sizes Some jewelry may still use the obsolete and significantly different Standard Wire Gauge (SWG) scale instead. Both AWG and SWG express sizes as a gauge, but the numbers are different. For example, AWG 12g is 2.1 mm, but SWG 12g is 2.6 mm. AWG 8g happens to be the same as SWG 10g. AWG 000g is 10.4 mm, but SWG 000g is 9.4 mm. In most discussions of body jewelry, sizes are specified by giving the gauge, usually abbreviated by the suffix "g", the same symbol as used for grams: "12g". The article American Wire Gauge system, section "Nomenclature and abbreviations in electrical distribution" shows other notations for gauge, but most are rarely used for expressing body jewelry sizes, except "ga." as in "12 ga.", which is used occasionally.
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Amasa Stone Frederick Harbach, a surveyor and engineer for several Ohio railroads, surveyed the route for the new spur in 1847. Stone had worked with Harbach and another railroad engineer, Stillman Witt, while building railroad bridges in New England. Alfred Kelley, an attorney and former state legislator, canal commissioner, banker, and railroad builder, was president of the railway, and he, too, knew Stone well from his railroading days in the east. Kelley and the CC&C managers reached out to Stone, Harbach, and Witt, and asked them to bid on the project. Stone, Harbach, and Witt formed a company in late 1848 to bid on the contract, which they then won. Construction began on the line in November 1849, and the final spike was driven on February 18, 1851. Stone, Harbach, and Witt agreed to take a portion of their pay in the form of stock in the railroad. The stock soared in value as soon as the spur was completed, making Stone very wealthy. In 1849, Stone, Harbach, and Witt also won a contract to build the Bellefontaine and Indiana Railroad. The Indiana portion of the line was finished in 1852, and the Ohio portion in July 1853. In 1850, Stone was appointed construction superintendent of the CC&C, and he moved to Cleveland. He was named a director of the railroad in 1852. Stone also became construction superintendent of another railroad in 1850, one that would eventually be known as the Lake Shore and Michigan Southern Railway (LS&MS)
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Weber County Main Library The Weber County Main Library, at 2464 Jefferson Ave. in Ogden, Utah, was listed on the National Register of Historic Places in 2019. It is a New Formalist style building designed by architect John L. Piers (1922–1997) and built in 1968. It is in plan. Others involved in its creation are Kenneth E. Hasenoehrl and Donald W. Mathewson as associate architects, and Edmund W. Allen. Piers also received assistance from Charlotte, North Carolina-based Galvin-Van Buren Associates.
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Placental lactogen Placental lactogen, also called chorionic somatomammotropin, is a polypeptide placental hormone, part of the somatotropin family. Its structure and function is similar to that of growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus. For information on the human form, see human placental lactogen. I and II were identified as prolactin-like molecules that can bind to prolactin receptor with high affinity and mimic the actions of prolactin. These hormones can contribute to lactogenesis, luteal maintenance and progesterone production (in rats) during the later stages of gestation. I may be important in stimulating mammary cell proliferation and in stimulating some of the adaptations of the maternal lipid and carbohydrate metabolism.
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Air Infiltration and Ventilation Centre The AIVC holds a conference each year in September/October in one of the AIVC participating countries, with around 50 to 150 presentations on a variety of topics in the air infiltration and ventilation fields. Since 1980, these annual conferences have been an international meeting point for presenting and discussing major developments and results regarding infiltration and ventilation in buildings. The proceedings of each conference are made available by the time of the next year's conference. The AIVC also organizes workshops, covering a wide range of topics in the field of infiltration and ventilation in buildings.
https://en.wikipedia.org/wiki?curid=41657867
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Preference-rank translation is a mathematical technique used by marketers to convert stated preferences into purchase probabilities, that is, into an estimate of actual buying behaviour. It takes survey data on consumers’ preferences and converts it into actual purchase probabilities. A survey might ask a question using a ranking scale such as : A marketing researcher will re-specify the numerical values during codification. 1 will become 5, 2 will become 4, 4 will become 2, 5 will become 1, and 3 will remain the same. In this way greater values will correspond with greater preference. Next, the researcher uses a data reduction technique like factor analysis to obtain aggregate scores. To convert these aggregate rankings into purchase probabilities, each category (in this case, each product) will be weighted with a translation coefficient. These weights are predefined. A typical weighting scheme is: The weighting schemes vary depending on the variables being measured. The following chart illustrates the procedure: Other purchase intention/rating translations include logit analysis and the intent scale translation.
https://en.wikipedia.org/wiki?curid=275524
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Anne C. Steinemann From 2015 she has been Professor of Civil Engineering, and Chair of Sustainable Cities, in the Department of Infrastructure Engineering at the University of Melbourne. Since 2007 Steinemann has focussed much of her research on "pollutant exposures and associated health effects, including topics of indoor air quality, consumer product testing and evaluation, exposure assessment, and healthy homes and communities". She has published research papers and monographs on the health effects of fragranced products (such as perfume, household cleaners, laundry supplies, personal care products, scented candles, air fresheners), concluding that those products "impair rather than improve indoor air quality" and "pose a range of health and economic risks." Her nationally representative population studies found that 34.7% of adults in the USA, 33.0% in Australia, 33.1% in Sweden, and 27.8% of people in the United Kingdom report adverse health effects from exposure to fragranced products. Adverse health effects include asthma attacks, breathing difficulties, migraine headaches, dizziness, seizures, rashes, and gastrointestinal problems. The effects are also economic with "more than 20% of respondents entering a business, but leaving as quickly as possible if they smell air fresheners or some fragranced product". She has found that emissions of carcinogenic pollutants from "green," "organic," and "all-natural" fragranced products were not significantly different from regular fragranced products
https://en.wikipedia.org/wiki?curid=53700387
336,865
Citizen science influence the science policy decisions that could impact their lives." Citizen involvement in scientific projects has become a means of encouraging curiosity and greater understanding of science whilst providing an unprecedented engagement between professional scientists and the general public. In a research report published by the National Park Service in 2008, Brett Amy Thelen and Rachel K. Thiet mention the following concerns, previously reported in the literature, about the validity of volunteer-generated data: The question of data accuracy, in particular, remains open. John Losey, who created the Lost Ladybug citizen science project, has argued that the cost-effectiveness of citizen science data can outweigh data quality issues, if properly managed. In December 2016, authors M. Kosmala, A. Wiggins, A. Swanson and B. Simmons published a study in the journal Frontiers in Ecology and the Environment called "Assessing Data Quality in Citizen Science". The abstract describes how ecological and environmental CS projects have enormous potential to advance science. Also, CS projects can influence policy and guide resource management by producing datasets that are otherwise infeasible to generate. In the section "In a Nutshell" (pg3), four condensed conclusions are stated. They are: They conclude that as CS continues to grow and mature, a key metric of project success they expect to see will be a growing awareness of data quality
https://en.wikipedia.org/wiki?curid=2155752
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Raychelle Burks is a Professor of analytical chemistry and science communicator at St. Edward's University in Austin, Texas. She was awarded the 2020 American Chemical Society Grady-Stack award for her public engagement excellence. Burks earned her BS in chemistry at Northern Iowa University, her MSc in Forensic Science at Nebraska Wesleyan University, and her PhD in chemistry from the University of Nebraska - Lincoln, and was a postdoctoral research associate at the Doane College. Burks current research centers on developing low-cost colorimetric sensors for detecting chemicals of forensic interest including explosives and illicit drugs. To maximize portability in the field, her group focuses on transforming smart phones into detection devices. Her research interests lie in the applied science domain, which she believes is well-suited to capturing and holding students' attention because they are working to solve real world problems. She has spoken about her intersectional research approach to equipping students with the technical knowledge they need to work on these real world challenges with the United States Department of Defense Science, Technology, and Innovation Exchange. Burks is a popular science communicator, using pop culture as an anchor to explore chemistry. She appeared on the Science Channel's "Outrageous Acts of Science" and "Reactions", the video series for the American Chemical Society
https://en.wikipedia.org/wiki?curid=57696483
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NATO Accessory Rail Further plans are underway to develop a NATO standard to provide electrical power to rail mounted accessories in the future. Currently, Wilcox Industries, in cooperation with Surefire, is working on the creation of a railed forend for an AR-15 that will power battery-reliant accessories such as tactical lights and laser sights. Accessories are intended to be powered by one central battery pack or via their proprietary vertical grip, the Universal Control Grip.
https://en.wikipedia.org/wiki?curid=24327497
423,259
USA Network To launch the new rights, Syfy and USA aired a joint marathon over the July 13-15, 2018 weekend, airing all eight films (including directors' cuts of the first six) with limited commercial interruption. has achieved a viewership foothold with its original programming; this began in the 1990s with initial hits such as "Silk Stalkings" and "La Femme Nikita", which were gradually followed in the following two decades by series such as "Monk", "Psych", "Shooter", "White Collar", "Covert Affairs", "Mr. Robot", "Suits", "Burn Notice" and "Royal Pains". Most of its original series are scripted dramas, some of which incorporate comedic elements. In addition to its original productions, the network airs syndicated reruns of current and former network series such as "", "Law & Order: Criminal Intent" (which spent the final four seasons of its run as a first-run program on USA) and "NCIS". The network also broadcasts a variety of films from the Universal Pictures library and select films from other movie studios (such as Walt Disney Studios Motion Pictures and Warner Bros. Entertainment), airing primarily as part of its overnight and weekend schedule, and occasionally during primetime on nights when original programming or marathons of its acquired programs are not scheduled. From 1984 to 2016, the network was the longtime home of the Westminster Kennel Club Dog Show
https://en.wikipedia.org/wiki?curid=77826
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Draining and development of the Everglades Along the way he built resort hotels, transforming territorial outposts into tourist destinations and the land bordering the rail lines into citrus farms. The winter of 1894–1895 produced a bitter frost that killed citrus trees as far south as Palm Beach. Miami resident Julia Tuttle sent Flagler a pristine orange blossom and an invitation to visit Miami, to persuade him to build the railroad farther south. Although he had earlier turned her down several times, Flagler finally agreed, and by 1896 the rail line had been extended to Biscayne Bay. Three months after the first train arrived, the residents of Miami, 512 in all, voted to incorporate the town. Flagler publicized Miami as a "Magic City" throughout the United States and it became a prime destination for the extremely wealthy after the Royal Palm Hotel was opened. Despite the sale of to Disston and the skyrocketing price of land, by the turn of the 20th century the IIF was bankrupt due to mismanagement. Legal battles ensued between the State of Florida and the railroad owners about who owned the rights to sell reclaimed land in the Everglades. In 1904 gubernatorial campaigning, the strongest candidate, Napoleon Bonaparte Broward, made draining the Everglades a major plank
https://en.wikipedia.org/wiki?curid=17375601
313,587
RoboCop Verhoeven chose to outfit Smith's character Clarence Boddicker in rimless glasses because of their intellectual association, creating a disparity in the character that Verhoeven found akin to the similarly bespectacled Heinrich Himmler. Filming began on August 6, 1986, and wrapped on October 20, 1986. The scenes depicting Murphy's death were not filmed until the following January (1987), some months after principal shooting had ceased. Although "RoboCop" is set in Detroit, Michigan, many of the urban settings in the film were actually filmed in Dallas, Texas. The futuristic appearances of the Dallas buildings, such as Reunion Tower, are visible in the background during the car chase. The front of Dallas City Hall was used as the exterior for the fictional OCP Headquarters, combined with extensive matte paintings to make the building appear taller than it actually is. The steel mill scenes were filmed at Wheeling-Pittsburgh Steel's Monessen Works, in the Pittsburgh suburb of Monessen, Pennsylvania. Peter Weller had prepared extensively for the role using a padded costume, as development of the actual suit was three weeks behind schedule. By the time shooting was under way and the costume had arrived on set, however, Weller discovered he was almost unable to move in it and needed additional training to become accustomed to it. Weller later revealed to Roger Ebert that during filming, he was losing three pounds a day due to sweat loss while wearing the suit in 100 °F (38 °C) temperatures
https://en.wikipedia.org/wiki?curid=445066
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History of computing hardware Replacement of the hard-to-implement decimal system (used in Charles Babbage's earlier design) by the simpler binary system meant that Zuse's machines were easier to build and potentially more reliable, given the technologies available at that time. The Z3 was probably a Turing-complete machine. In two 1936 patent applications, Zuse also anticipated that machine instructions could be stored in the same storage used for data—the key insight of what became known as the von Neumann architecture, first implemented in 1948 in America in the electromechanical IBM SSEC and in Britain in the fully electronic Manchester Baby. Zuse suffered setbacks during World War II when some of his machines were destroyed in the course of Allied bombing campaigns. Apparently his work remained largely unknown to engineers in the UK and US until much later, although at least IBM was aware of it as it financed his post-war startup company in 1946 in return for an option on Zuse's patents. In 1944, the Harvard Mark I was constructed at IBM's Endicott laboratories; it was a similar general purpose electro-mechanical computer to the Z3, but was not quite Turing-complete. The term digital was first suggested by George Robert Stibitz and refers to where a signal, such as a voltage, is not used to directly represent a value (as it would be in an analog computer), but to encode it
https://en.wikipedia.org/wiki?curid=13636
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Ingress filtering The best current practices for network ingress filtering are documented by the Internet Engineering Task Force in BCP 38 and BCP 84, which are defined by RFC 2827 and RFC 3704, respectively. BCP 84 recommends that upstream providers of IP connectivity filter packets entering their networks from downstream customers, and discard any packets which have a source address which is not allocated to that customer. There are many possible ways of implementing this policy; one common mechanism is to enable reverse path forwarding on links to customers, which will indirectly apply this policy based on the provider's route filtering of their customers' route announcements. As of 2012, one report suggests that, contrary to general opinion about the lack of BCP 38 deployment, some 80% of the Internet (by various measures) were already applying anti-spoofing packet filtering in their networks.
https://en.wikipedia.org/wiki?curid=3021212
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Thiophosphate Dithiophosphate has the formula [POS], which has C symmetry. Sodium dithiophosphate, which is colorless, is the major product from the reaction of phosphorus pentasulfide with NaOH: Dithiophosphoric acid is obtained by treatment of barium dithiophosphate with sulfuric acid: Both NaPOS and especially HPOS are prone toward hydrolysis to their monothio derivatives. Trithiophosphate is the anion [POS], which has C symmetry. Tetrathiophosphate is the anion [PS], which has T symmetry. A number of these anions known. Some have attracted interest as components in fast ion conductors for use in solid state batteries. The binary thiophosphates do not exhibit the extensive diversity of the analogous P-O anions but contain similar structural features, for example P is 4 coordinate, P−S−P links form and there are P−P bonds. One difference is that ions may include polysulfide fragments of 2 or more S atoms whereas in the P−O anions there is only the reactive −O−O−, peroxo, unit.
https://en.wikipedia.org/wiki?curid=15516194
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Endogenous cardiac stem cell It has also been reported that Flk-1 is not a specific marker for endogenous and mouse ESC-derived Isl1+ CPCs. While some eCSC discoveries have been brought into question, there has been success with other membrane markers. For instance, it was demonstrated that the combination of Flt1+/Flt4+ membrane markers identifies an Isl1+/Nkx2.5+ cell population in the developing heart. It was also shown that endogenous Flt1+/Flt4+ cells could be expanded in vitro and displayed trilineage differentiation potential. Flt1+/Flt4+ CPCs derived from iPSCs were shown to engraft into the adult myocardium and robustly differentiate into cardiomyocytes with phenotypic and electrophysiologic characteristics of adult cardiomyocytes. With the myocardium now recognized as a tissue with limited regenerating potential, harbouring eCSCs that can be isolated and amplified in vitro for regenerative protocols of cell transplantation or stimulated to replicate and differentiate in situ in response to growth factors, it has become reasonable to exploit this endogenous regenerative potential to replace lost/damaged cardiac muscle with autologous functional myocardium.
https://en.wikipedia.org/wiki?curid=34347729
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Separatory funnel A separatory funnel, also known as a separation funnel, separating funnel, or colloquially sep funnel, is a piece of laboratory glassware used in liquid-liquid extractions to separate ("partition") the components of a mixture into two immiscible solvent phases of different densities. Typically, one of the phases will be aqueous, and the other a lipophilic organic solvent such as ether, MTBE, dichloromethane, chloroform, or ethyl acetate. All of these solvents form a clear delineation between the two liquids. The more dense liquid, typically the aqueous phase unless the organic phase is halogenated, sinks and can be drained out through a valve away from the less dense liquid, which remains in the separatory funnel. A separating funnel takes the shape of a cone with a hemispherical end. It has a stopper at the top and stopcock (tap), at the bottom. Separating funnels used in laboratories are typically made from borosilicate glass and their stopcocks are made from glass or PTFE. Typical sizes are between 30 mL and 3 L. In industrial chemistry they can be much larger and for much larger volumes centrifuges are used. The sloping sides are designed to facilitate the identification of the layers. The stopcock-controlled outlet is designed to drain the liquid out of the funnel. On top of the funnel there is a standard taper joint which fits with a ground glass or Teflon stopper
https://en.wikipedia.org/wiki?curid=1745432
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Dematic designs and manufactures individual products and material handling equipment such as automated storage and retrieval systems (AS/RS) and different types of conveyors, sortation systems and order picking systems. also offers consultative, planning, and design services that integrate hardware and software components into total logistics solutions. In addition, the company provides software and IT solutions like warehouse management systems and systems that support material flow and paperless order picking operations. also offers customer services such as the technical operation of facilities and their maintenance, including complete enterprise asset management.
https://en.wikipedia.org/wiki?curid=28345193
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Crookes tube By the time the inside of the tube became dark, they were able to travel in straight lines from the cathode to the anode, without a collision. They were accelerated to a high velocity by the electric field between the electrodes, both because they did not lose energy to collisions, and also because Crookes tubes were operated at a higher voltage. By the time they reached the anode end of the tube, they were going so fast that many flew past the anode and hit the glass wall. The electrons themselves were invisible, but when they hit the glass walls of the tube they excited the atoms in the glass, making them give off light or fluoresce, usually yellow-green. Later experimenters painted the back wall of Crookes tubes with fluorescent paint, to make the beams more visible. This accidental fluorescence allowed researchers to notice that objects in the tube, such as the anode, cast a sharp-edged shadow on the tube wall. Johann Hittorf was first to recognise in 1869 that something must be travelling in straight lines from the cathode to cast the shadow. In 1876, Eugen Goldstein proved that they came from the cathode, and named them "cathode rays" ("Kathodenstrahlen"). At the time, atoms were the smallest particles known and were believed to be indivisible, the electron was unknown, and what carried electric currents was a mystery. During the last quarter of the 19th century, many ingenious types of Crookes tubes were invented and used in historic experiments to determine what cathode rays were (see below)
https://en.wikipedia.org/wiki?curid=1930784
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Switchgear The switchgear on the low-voltage side of the transformers may be located in a building, with medium-voltage circuit breakers for distribution circuits, along with metering, control, and protection equipment. For industrial applications, a transformer and switchgear line-up may be combined in one housing, called a unitized substation (USS). According to the latest research by visiongain, the worldwide switchgear market is expected to achieve $152.5 billion by 2029 at a CAGR of 5.9%. Growing investment in renewable energy and enhanced demand for safe and secure electrical distribution systems are expected to generate the increase. A switchgear assembly has two types of components: One of the basic functions of switchgear is protection, which is interruption of short-circuit and overload fault currents while maintaining service to unaffected circuits. also provides isolation of circuits from power supplies. is also used to enhance system availability by allowing more than one source to feed a load. Switchgears are as old as electricity generation. The first models were very primitive: all components were simply fixed to a wall. Later they were mounted on wooden panels. For reasons of fire protection, the wood was replaced by slate or marble. This led to a further improvement, because the switching and measuring devices could be attached to the front, while the wiring was on the back.
https://en.wikipedia.org/wiki?curid=1561900
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High fidelity Olson conducted an experiment whereby test subjects listened to a live orchestra through a hidden variable acoustic filter. The results proved that listeners preferred high-fidelity reproduction, once the noise and distortion introduced by early sound equipment was removed. Beginning in 1948, several innovations created the conditions that made major improvements of home-audio quality possible: In the 1950s, audio manufacturers employed the phrase "high fidelity" as a marketing term to describe records and equipment intended to provide faithful sound reproduction. While some consumers simply interpreted "high fidelity" as fancy and expensive equipment, many found the difference in quality compared to the then-standard AM radios and 78-rpm records readily apparent and bought high-fidelity phonographs and 33⅓ LPs such as RCA's New Orthophonics and London's ffrr (Full Frequency Range Recording, a UK Decca system). Audiophiles paid attention to technical characteristics and bought individual components, such as separate turntables, radio tuners, preamplifiers, power amplifiers and loudspeakers. Some enthusiasts even assembled their own loudspeaker systems. In the 1950s, "hi-fi" became a generic term for home sound equipment, to some extent displacing "phonograph" and "record player". In the late 1950s and early 1960s, the development of stereophonic equipment and recodings led to the next wave of home-audio improvement, and in common parlance "stereo" displaced "hi-fi". Records were now played on "a stereo"
https://en.wikipedia.org/wiki?curid=13624
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Automatic transmission The lack of manual shifting also reduces the attention and workload required inside the cabin, such as monitoring the tachometer and taking a hand off the wheel to move the shifter, allowing the driver to ideally keep both hands on the wheel at all times and to focus more on the road. Control of the car at low speeds is often easier with an automatic than a manual, due to a side effect of the clutchless fluid-coupling design called idle creep that causes the car to slowly move on its own while in a driving gear, even at idle. The primary disadvantage of the most popular hydraulic designs is reduced mechanical efficiency of the power transfer between engine and drivetrain, due to the fluid coupling connecting the engine to the gearbox. This can result in lower power/torque ratings for automatics compared to manuals with the same engine specs, as well as reduced fuel efficiency in city driving as the engine must maintain idle against the resistance of the fluid coupling. Advances in transmission and coupler design have narrowed this gap considerably, but clutch-based transmissions (manual or semi-automatic) are still preferred in sport-tuned trim levels of various production cars, as well as in many auto racing leagues. The automatic transmission was invented in 1921 by Alfred Horner Munro of Regina, Saskatchewan, Canada, and patented under Canadian patent CA 235757 in 1923. (Munro obtained UK patent GB215669 215,669 for his invention in 1924 and US patent 1,613,525 on 4 January 1927)
https://en.wikipedia.org/wiki?curid=334940
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Carbon monoxide detector This can either be seen directly or connected to an infrared source of photons such as an IR LED and then monitored using a photodiode. Battery lifespan usually lasts 2–3 years with conventional alkaline, but a lithium battery will last the life of the product. The biotechnology based sensors have a useful operational life of 6 years. These products were the first to enter the mass market, but because they cost more than other sensors they are mostly used in higher-end areas and RVs. The technology has been improved and is the most reliable technology, according to a report from Lawrence Berkeley National Laboratory. The technology is the only one tested false alarm free and is preferred by those with larger facilities like hospitals, hotels and apartments that use air fresheners, alcohols and other disinfectants where the cost of one false alarm is very high. This technology was invented in the United States and is manufactured in California. The electrochemical detector uses the principle of a fuel cell to generate an electrical current when the gas to be detected undergoes a chemical reaction. The generated current is precisely related to the amount of carbon monoxide in the immediate environment close to the sensor. Essentially, the electrochemical cell consists of a container, two electrodes, connection wires and an electrolyte, typically sulfuric acid. Carbon monoxide is oxidized at one electrode to carbon dioxide while oxygen is consumed at the other electrode
https://en.wikipedia.org/wiki?curid=2930061
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Cost of poor quality He defined the following costs by functional area: The damages of poor quality augment as the inception point is further down the supply chain: TCFP [Total Cost of Faulty Part] = Direct Cost (manufacturing cost) + Labor Cost (assembly and testing) + Overhead Cost (Inventory, handling, shipping costs) + Scrapping Cost (of part and attached parts assemblies: Sometimes assemblies cannot be disassembled and have to be scrapped altogether) + Rework (applying a new part instead) + Repair / Recall Costs (these are costs associated with repairing or replacing a new part / assembly under warranty) + Product Liability Costs (These are costs resulting from damages caused by the faulty part to 3rd parties)
https://en.wikipedia.org/wiki?curid=11730635
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KaiC Additionally, overexpression of has been shown to strongly repress the "kaiBC" promoter, while "kaiA" overexpression has experimentally enhanced the "kaiBC" promoter. These positive and negative binding elements mirror a feedback mechanism of rhythm generation conserved across many different species. phosphorylation oscillates with a period of approximately 24 hours when placed in vitro with the three recombinant Kai proteins, incubated with ATP. The circadian rhythm of phosphorylation persists in constant darkness, regardless of "Synechococcus" transcription rates. This oscillation rate is thought to be controlled by the ratio of phosphorylated to unphosphorylated protein. phosphorylation ratio is a main factor in the activation of "kaiBC" promoter as well. The "kaiBC" operon is transcribed in a circadian fashion and precedes build up by about 6 hours, a lag thought to play a role in feedback loops. "kaiA", "kaiB", and "kaiC" have been shown to be essential genetic components in "Synechococcus elongatus" for circadian rhythms. Experiments have also shown that enhances the KaiA-KaiB interaction in yeast cells and in vitro. This implies that there may be the formation of a heteromultimeric complex composed of the three Kai proteins with serving as a bridge between KaiA and KaiB. Alternatively, may form a heterodimer with KaiA or KaiB to induce a conformational change
https://en.wikipedia.org/wiki?curid=39103747
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Active suspension An active suspension is a type of automotive suspension on a vehicle. It uses an onboard system to control the vertical movement of the vehicle's wheels relative to the chassis or vehicle body rather than the passive suspension provided by large springs where the movement is determined entirely by the road surface. So-called active suspensions are divided into two classes: real active suspensions, and adaptive or semi-active suspensions. While adaptive suspensions only vary shock absorber firmness to match changing road or dynamic conditions, active suspensions use some type of actuator to raise and lower the chassis independently at each wheel. These technologies allow car manufacturers to achieve a greater degree of ride quality and car handling by keeping the tires perpendicular to the road in corners, allowing better traction and control. An onboard computer detects body movement from sensors throughout the vehicle and, using that data, controls the action of the active and semi-active suspensions. The system virtually eliminates body roll and pitch variation in many driving situations including cornering, accelerating, and braking. Skyhook theory is that the ideal suspension would let the vehicle maintain a stable posture as if suspended by an imaginary hook in the sky, unaffected by road conditions. Since an actual skyhook is impractical, real active suspension systems are based on actuator operations
https://en.wikipedia.org/wiki?curid=7667706
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Displacement chromatography The chromatographic purification of proteins from complex mixtures can be quite challenging, particularly when the mixtures contain similarly retained proteins or when it is desired to enrich trace components in the feed. Further, column loading is often limited when high resolutions are required using traditional modes of chromatography (e.g. linear gradient, isocratic chromatography). In these cases, displacement chromatography is an efficient technique for the purification of proteins from complex mixtures at high column loadings in a variety of applications. An important advance in the state of the art of displacement chromatography was the development of low molecular mass displacers for protein purification in ion exchange systems. This research was significant in that it represented a major departure from the conventional wisdom that large polyelectrolyte polymers are required to displace proteins in ion exchange systems. Low molecular mass displacers have significant operational advantages as compared to large polyelectrolyte displacers. For example, if there is any overlap between the displacer and the protein of interest, these low molecular mass materials can be readily separated from the purified protein during post-displacement processing using standard size-based purification methods (e.g. size exclusion chromatography, ultrafiltration). In addition, the salt-dependent adsorption behavior of these low MW displacers greatly facilitates column regeneration
https://en.wikipedia.org/wiki?curid=15881178
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Industrial Revolution The demand for cotton presented an opportunity to planters in the Southern United States, who thought upland cotton would be a profitable crop if a better way could be found to remove the seed. Eli Whitney responded to the challenge by inventing the inexpensive cotton gin. A man using a cotton gin could remove seed from as much upland cotton in one day as would previously, working at the rate of one pound of cotton per day, have taken a woman two months to process. These advances were capitalised on by entrepreneurs, of whom the best known is Richard Arkwright. He is credited with a list of inventions, but these were actually developed by such people as Thomas Highs and John Kay; Arkwright nurtured the inventors, patented the ideas, financed the initiatives, and protected the machines. He created the cotton mill which brought the production processes together in a factory, and he developed the use of powerfirst horse power and then water powerwhich made cotton manufacture a mechanised industry. Other inventors increased the efficiency of the individual steps of spinning (carding, twisting and spinning, and rolling) so that the supply of yarn increased greatly. Before long steam power was applied to drive textile machinery. Manchester acquired the nickname Cottonopolis during the early 19th century owing to its sprawl of textile factories
https://en.wikipedia.org/wiki?curid=14914
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Invention of radio Ørsted's work influenced André-Marie Ampère to produce a theory of electromagnetism. Several scientists speculated that light might be connected with electricity or magnetism. In 1831, Michael Faraday began a series of experiments in which he discovered electromagnetic induction. The relation was mathematically modelled by Faraday's law, which subsequently became one of the four Maxwell equations. Faraday proposed that electromagnetic forces extended into the empty space around the conductor, but did not complete his work involving that proposal. In 1846 Michael Faraday speculated that light was a wave disturbance in a force field". Expanding upon a series of experiments by Felix Savary, between 1842 and 1850 Joseph Henry performed experiments detecting inductive magnetic effects over a distance of . He was the first (1838–42) to produce high frequency AC electrical oscillations, and to point out and experimentally demonstrate that the discharge of a capacitor under certain conditions is oscillatory, or, as he puts it, consists ""of a principal discharge in one direction and then several reflex actions backward and forward, each more feeble than the preceding until equilibrium is attained"". This view was also later adopted by Helmholtz, the mathematical demonstration of this fact was first given by Lord Kelvin in his paper on "Transient Electric Currents"
https://en.wikipedia.org/wiki?curid=3800477
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Analogue filter This gives Butterworth the credit for being both the first to deviate from image parameter theory and the first to design active filters. It was later shown that Butterworth filters could be implemented in ladder topology without the need for amplifiers. Possibly the first to do so was William Bennett (1932) in a patent which presents formulae for component values identical to the modern ones. Bennett, at this stage though, is still discussing the design as an artificial transmission line and so is adopting an image parameter approach despite having produced what would now be considered a network synthesis design. He also does not appear to be aware of the work of Butterworth or the connection between them. The insertion-loss method of designing filters is, in essence, to prescribe a desired function of frequency for the filter as an attenuation of the signal when the filter is inserted between the terminations relative to the level that would have been received were the terminations connected to each other via an ideal transformer perfectly matching them. Versions of this theory are due to Sidney Darlington, Wilhelm Cauer and others all working more or less independently and is often taken as synonymous with network synthesis. Butterworth's filter implementation is, in those terms, an insertion-loss filter, but it is a relatively trivial one mathematically since the active amplifiers used by Butterworth ensured that each stage individually worked into a resistive load
https://en.wikipedia.org/wiki?curid=23431648
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Diatomaceous earth "Amorphous" silica is considered to have low toxicity, but prolonged inhalation causes changes to the lungs. is mostly amorphous silica, but contains some crystalline silica, especially in the saltwater forms. In a study of workers, those exposed to natural D.E. for over 5 years had no significant lung changes, while 40% of those exposed to the calcined form had developed pneumoconiosis.Today's common D.E. formulations are safer to use as they are predominantly made up of amorphous silica and contain little or no crystalline silica. The crystalline silica content of D.E. is regulated in the United States by the Occupational Safety and Health Administration (OSHA), and there are guidelines from the National Institute for Occupational Safety and Health setting maximum amounts allowable in the product (1%) and in the air near the breathing zone of workers, with a recommended exposure limit at 6 mg/m over an 8-hour workday. OSHA has set a permissible exposure limit for diatomaceous earth as 20 mppcf (80 mg/m/%SiO). At levels of 3000 mg/m, diatomaceous earth is immediately dangerous to life and health. In the 1930s, long-term occupational exposure among workers in the cristobalite D.E. industry who were exposed to high levels of airborne crystalline silica over decades were found to have an increased risk of silicosis. Today, workers are required to use respiratory-protection measures when concentrations of silica exceed allowable levels
https://en.wikipedia.org/wiki?curid=773959
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Electrodermal activity (EDA) is the property of the human body that causes continuous variation in the electrical characteristics of the skin. Historically, EDA has also been known as skin conductance, galvanic skin response (GSR), electrodermal response (EDR), psychogalvanic reflex (PGR), skin conductance response (SCR), sympathetic skin response (SSR) and skin conductance level (SCL). The long history of research into the active and passive electrical properties of the skin by a variety of disciplines has resulted in an excess of names, now standardized to electrodermal activity (EDA). The traditional theory of EDA holds that skin resistance varies with the state of sweat glands in the skin. Sweating is controlled by the sympathetic nervous system, and skin conductance is an indication of psychological or physiological arousal. If the sympathetic branch of the autonomic nervous system is highly aroused, then sweat gland activity also increases, which in turn increases skin conductance. In this way, skin conductance can be a measure of emotional and sympathetic responses. More recent research and additional phenomena (resistance, potential, impedance, and admittance, sometimes responsive and sometimes apparently spontaneous) suggest that EDA is more complex than it seems, and research continues into the source and significance of EDA. In 1849, Dubois-Reymond in Germany first observed that human skin was electrically active
https://en.wikipedia.org/wiki?curid=1001343
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Corkscrew The wing corkscrew, sometimes called cork-extactor, a butterfly corkscrew, owl corkscrew or angel corkscrew, has two levers, one on either side of the worm. As the worm is twisted into the cork, the levers are raised. Pushing down the levers draws the cork from the bottle in one smooth motion. The most common design has a rack and pinion connecting the levers to the body. The head of the central shaft is frequently modified to form a bottle opener, increasing the utility of the device. Corkscrews of this design are particularly popular in household use. A sommelier knife, waiter's friend or wine key is a corkscrew in a folding body similar to a pocket knife. It was conceived by the German Karl Wienke in 1882 and patented in Germany, England, and America. An arm extends to brace against the lip of the bottle for leverage when removing the cork. Some sommelier knives have two steps on the lever, and often also a bottle opener. A small hinged knife blade is housed in the handle end to be used in cutting the foil wrapping the neck of many wine bottles. A corkscrew of this type can be used more quickly (and with more "show" or panache) than a wing-type corkscrew. The term "wine key" came into existence due to the German inventor's last name, Wienke, which is difficult for English speakers to pronounce. When ordering the product from catalogs, the meaning and origins of the new Wienke gradually became lost and it was simply referred to as a "Winekey" or wine key
https://en.wikipedia.org/wiki?curid=916552
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Rolling-element bearing However, a load on an infinitely small point would cause infinitely high contact pressure. In practice, the ball deforms (flattens) slightly where it contacts each race much as a tire flattens where it contacts the road. The race also yields slightly where each ball presses against it. Thus, the contact between ball and race is of finite size and has finite pressure. The deformed ball and race do not roll entirely smoothly because different parts of the ball are moving at different speeds as it rolls. Thus, there are opposing forces and sliding motions at each ball/race contact. Overall, these cause bearing drag. Roller bearings are the earliest known type of rolling-element-bearing, dating back to at least 40 BC. Common roller bearings use cylinders of slightly greater length than diameter. Roller bearings typically have higher radial load capacity than ball bearings, but a lower capacity and higher friction under axial loads. If the inner and outer races are misaligned, the bearing capacity often drops quickly compared to either a ball bearing or a spherical roller bearing. As in all radial bearings, the outer load is continuously re-distributed among the rollers. Often fewer than half of the total number of rollers carry a significant portion of the load. The animation on the right shows how a static radial load is supported by the bearing rollers as the inner ring rotates. Spherical roller bearings have an outer ring with an internal spherical shape
https://en.wikipedia.org/wiki?curid=627542
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Spark-gap transmitter The only other way to increase the energy stored in the antenna was to charge it up to very high voltages. However the voltage that could be used was limited to about 100 kV by corona discharge which caused charge to leak off the antenna, particularly in wet weather, and also energy lost as heat in the longer spark. A more significant drawback of the large damping was that the radio transmissions were electrically "noisy"; they had a very large bandwidth. These transmitters did not produce waves of a single frequency, but a continuous band of frequencies. They were essentially radio noise sources radiating energy over a large part of the radio spectrum, which made it impossible for other transmitters to be heard. When multiple transmitters attempted to operate in the same area, their broad signals overlapped in frequency and interfered with each other. The radio receivers used also had no resonant circuits, so they had no way of selecting one signal from others besides the broad resonance of the antenna, and responded to the transmissions of all transmitters in the vicinity. An example of this interference problem was an embarrassing public debacle in August 1901 when Marconi, Lee De Forest, and another group attempted to report the New York Yacht Race to newspapers from ships with their untuned spark transmitters. The Morse code transmissions interfered, and the reporters on shore failed to receive any information from the garbled signals
https://en.wikipedia.org/wiki?curid=1105907
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Overlap zone An overlap zone, in radio frequency engineering, is a zone in which the signals from two or more radio stations, transmitting at the same frequency, can be received with comparable intensity. Interference occurs frequently in such a zone. In order to avoid this, a receiver with directional antenna is used, which can then be aligned in such a way that it will only receive the signal of one transmitter. Alternatively, the signals could be separated using a demodulator in single sideband mode. With digital radio (Digital Radio Mondiale and Digital Audio Broadcasting being two common types), there is no interference in the overlap zone. 1 - Multifunctional Ultrawideband Antennas Trends, Techniques and Applications By Chinmoy Saha, Jawad Y. Siddiqui, and Yahia M.M. Antar - 2019. P.3 - P.11 - P.46, 47 - P.65.
https://en.wikipedia.org/wiki?curid=858412
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Game theory In non-cooperative games, the most famous of these is the Nash equilibrium. A set of strategies is a Nash equilibrium if each represents a best response to the other strategies. If all the players are playing the strategies in a Nash equilibrium, they have no unilateral incentive to deviate, since their strategy is the best they can do given what others are doing. The payoffs of the game are generally taken to represent the utility of individual players. A prototypical paper on game theory in economics begins by presenting a game that is an abstraction of a particular economic situation. One or more solution concepts are chosen, and the author demonstrates which strategy sets in the presented game are equilibria of the appropriate type. Naturally one might wonder to what use this information should be put. Economists and business professors suggest two primary uses (noted above): "descriptive" and "prescriptive". Sensible decision-making is critical for the success of projects. In project management, game theory is used to model the decision-making process of players, such as investors, project managers, contractors, sub-contractors, governments and customers. Quite often, these players have competing interests, and sometimes their interests are directly detrimental to other players, making project management scenarios well-suited to be modeled by game theory. Piraveenan (2019) in his review provides several examples where game theory is used to model project management scenarios
https://en.wikipedia.org/wiki?curid=11924
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Samuel King Allison He was so impressed by the Cavendish Laboratory's Cockcroft–Walton accelerator that after returning to Chicago he built one. During World War II, Allison became involved in defence-related work. He was a consultant to the National Defense Research Committee (NDRC) from October 1940 to January 1941. In January 1941 the NDRC let him a contract to study the possibility of using beryllium as a neutron moderator. The team he assembled in Chicago would grow into the Manhattan Project's Metallurgical Laboratory. In September 1941, Allison joined the S-1 Section, which coordinated the early investigations into the feasibility of an atomic bomb. He began building a reactor in the squash courts under the disused stands of Stagg Field. He became head of the Metallurgical Laboratory's chemistry section in January 1942, and in March, his small experimental reactor using beryllium came closer to criticality than the graphite-moderated design of Enrico Fermi's group at Columbia University. During 1942, Compton brought all the research groups working on plutonium and nuclear reactor design at Columbia University, Princeton University and the University of California together at the Metallurgical Laboratory in Chicago. Allison was placed in charge of the experimental work. By October 1942, the Metallurgical Laboratory had to consider how it would proceed with designing large production reactors when they had yet to get an experimental reactor to work
https://en.wikipedia.org/wiki?curid=2594225
280,894
Green infrastructure The city did not stop there, and decided in the 2000s to harness the redevelopment progress for even better environmental outcomes, in particular that related to stormwater runoff, by requiring in 2005 the use of on-site GI practices in all new private development projects. The city faced several challenges, including a high water table, tidal flows, clay soils, contaminated soil and water, and few absorbent natural areas among the primarily impervious, paved parcels of existing and redeveloped industrial sites. The guidelines, and an accompanying spreadsheet model, were developed to make as much use of redevelopment sites as possible for handling stormwater. The main strategies fell into several categories: The Gowanus Canal, in Brooklyn, New York, is bounded by several communities including Park Slope, Cobble Hill, Carroll Gardens, and Red Hook. The canal empties into New York Harbor. Completed in 1869, the canal was once a major transportation route for the then separate cities of Brooklyn and New York City. Manufactured gas plants, mills, tanneries, and chemical plants are among the many facilities that operated along the canal. As a result of years of discharges, storm water runoff, sewer outflows, and industrial pollutants, the canal has become one of the nation's most extensively contaminated water bodies. Contaminants include PCBs, coal tar wastes, heavy metals, and volatile organics. On March 2, 2010, EPA added the canal to its Superfund National Priorities List (NPL)
https://en.wikipedia.org/wiki?curid=10040229
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MOSFET To reduce the resulting leakage current, the insulator can be made thinner by choosing a material with a higher dielectric constant. To see how thickness and dielectric constant are related, note that Gauss's law connects field to charge as: with "Q" = charge density, κ = dielectric constant, ε = permittivity of empty space and "E" = electric field. From this law it appears the same charge can be maintained in the channel at a lower field provided κ is increased. The voltage on the gate is given by: with "V" = gate voltage, "V" = voltage at channel side of insulator, and "t" = insulator thickness. This equation shows the gate voltage will not increase when the insulator thickness increases, provided κ increases to keep "t" / κ = constant (see the article on high-κ dielectrics for more detail, and the section in this article on gate-oxide leakage). The insulator in a is a dielectric which can in any event be silicon oxide, formed by LOCOS but many other dielectric materials are employed. The generic term for the dielectric is gate dielectric since the dielectric lies directly below the gate electrode and above the channel of the MOSFET
https://en.wikipedia.org/wiki?curid=40345
22,846
Context-based access control This state information is used to create temporary openings in the firewall's access lists to allow return traffic and additional data connections for permissible sessions (sessions that originated from within the protected internal network). CBAC works through deep packet inspection and hence Cisco calls it 'IOS firewall' in their Internetwork Operating System (IOS). CBAC also provides the following benefits:
https://en.wikipedia.org/wiki?curid=2004122
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MPEG user data The feature provides a means to inject application-specific data into an MPEG elementary stream. User data can be inserted on three different levels: Applications that process MPEG data do not need to be able to understand data encapsulated in this way, but should be able to preserve it. Examples of information embedded in MPEG streams as user data are:
https://en.wikipedia.org/wiki?curid=1225458
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Shenzhen Metro Mobile phone service is available throughout the system provided by China Mobile, China Telecom, and China Unicom. Like the Hong Kong MTR, Guangzhou, and Foshan metros, station announcements are in Mandarin, Cantonese and English. Some announcements, such as train arrival, are in Mandarin and English only. Cantonese, an important local language, is chosen for the local Cantonese population as well as Cantonese speakers in Guangdong, Hong Kong and Macau. On Line 1 and Line 4, Siemens Transportation Systems supplied 7 (Phase 1) and 6 (Phase 2) LZB 700 M continuous automatic control systems; 7 (Phase 1) and 6 (Phase 2) electronic Sicas ESTT interlockings; the Vicos OC 501 operations control system with 2 operations control centers, fall-back level with Vicos OC 101 and RTU (FEP), 230 (Phase 1) and 240 (Phase 2) FTG S track vacancy detection units. Line 2 and Line 5 use Casco CBTC system with 2.4 GHz frequencies, and so the system has suffered frequent problems with interference from consumer Wi-Fi equipment. By the end of November 2012, CASCO solved the problem on Lines 2 and 5 by switching to their standard solution with frequency diversity on 2 different channels.
https://en.wikipedia.org/wiki?curid=1372941
211,596