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Penicillin The pH and the levels of nitrogen, lysine, phosphate, and oxygen of the batches must also be carefully controlled. The biotechnological method of directed evolution has been applied to produce by mutation a large number of "Penicillium" strains. These techniques include error-prone PCR, DNA shuffling, ITCHY,...
https://en.wikipedia.org/wiki?curid=23312
154,288
Synthetic genomics Soon after the discovery of restriction endonucleases and ligases, the field of genetics began using these molecular tools to assemble artificial sequences from smaller fragments of synthetic or naturally-occurring DNA. The advantage in using the recombinatory approach as opposed to continual DNA syn...
https://en.wikipedia.org/wiki?curid=11330015
193,569
Safe operating area ) will carry a lower current density, tending to even out any temperature variation and prevent hot spots. Recently, MOSFETs with very high transconductance, optimised for switching operation, have become available. When operated in linear mode, especially at high drain-source voltages and low drain...
https://en.wikipedia.org/wiki?curid=976730
389,772
Tariff Thus, the damage done could not possibly have exceeded 1 or 2 percent of world GDP — nowhere near the 17 percent falloff seen during the Great Depression... The inescapable conclusion: contrary to public perception, Smoot-Hawley did not cause, or even significantly deepen, the Great Depression," Nobel laureate M...
https://en.wikipedia.org/wiki?curid=55551
509,853
Robert Lusch In 2009 the AMA awarded him its IOSIG Lifetime Achievement Award, and in 2010 he was the recipient of the AMA/Sheth Foundation Award for long-standing contributions to marketing literature. In February 2013 Lusch was presented the AMA/Irwin/McGraw-Hill Distinguished Marketing Educator Award.
https://en.wikipedia.org/wiki?curid=24788943
452,049
1999 Aggie Bonfire collapse On October 28, 2008, Texas A&M settled the final lawsuit filed against them by the victims and their families. The university agreed to pay $2.1 million and promised that if the bonfire returned to campus that "engineering oversight" would be provided. The final lawsuit, filed against two co...
https://en.wikipedia.org/wiki?curid=55796803
342,934
Cairo Citadel More significantly in the long run, Qalawun was the first to create elite regiments of mamluks (soldiers of slave origin) who resided in the various towers of the Citadel, which earned them the name "Burji" Mamluks (Mamluks of the Tower). It was these cohorts of mamluks who would eventually dominate the s...
https://en.wikipedia.org/wiki?curid=2814371
317,503
Dynamic range compression Compression is often applied in audio systems for restaurants, retail, and similar public environments that play background music at a relatively low volume and need it compressed, not just to keep the volume fairly constant, but also to make quiet parts of the music audible over ambient noise...
https://en.wikipedia.org/wiki?curid=262733
227,215
Long non-coding RNA Similar models have been proposed in mammals, where strong epigenetic mechanisms are thought to underlie the embryonic expression profiles of the Hox genes that persist throughout human development. Indeed, the human Hox genes are associated with hundreds of ncRNAs that are sequentially expressed al...
https://en.wikipedia.org/wiki?curid=16770101
297,571
Reynolds stress Thus, by analogy, the is sometimes thought of as consisting of an isotropic pressure part, termed the turbulent pressure, and an off-diagonal part which may be thought of as an effective turbulent viscosity. In fact, while much effort has been expended in developing good models for the in a fluid, as a ...
https://en.wikipedia.org/wiki?curid=1852294
202,685
Founder effect Around 1814, a small group of British colonists founded a settlement on Tristan da Cunha, a group of small islands in the Atlantic Ocean, midway between Africa and South America. One of the early colonists apparently carried a rare, recessive allele for retinitis pigmentosa, a progressive form of blindne...
https://en.wikipedia.org/wiki?curid=392309
174,348
Roof cleaning based Asphalt Roofing Manufactureres' Association specifies the use of a bleach cleaning solution, without the use of a pressure washer, to remove algae from a roof. ARMA discourages the use of a pressure washer, a flat-surface cleaner or any other mechanical device to clean a roof. Safe, effective soft w...
https://en.wikipedia.org/wiki?curid=28553041
362,646