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5 concentrations were computed for each participant using a hierarchical spatiotemporal model fit with a pragmatic estimation procedure described elsewhere [30,31].
method
Methods
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9b7d3cee2c9379610a564ac563f3795b11805f01
Importantly, none of these studies have attempted to simultaneously examine the influences of individualand neighborhood-SES, the built environment, and the social dimensions of neighborhoods (Ding et al., 2011).
background
1. Introduction
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We recently cloned, mapped and functionally characterized P450 1A5 (Yip and Coulombe, 2006) and 3A37 (Rawal et al., 2010b; Rawal et al., 2009) from turkey liver, which, like their human orthologs, produced exo-AFBO, and the detoxified metabolites aflatoxin M1 (AFM1) and aflatoxin Q1 (AFQ1),…
method
Introduction
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ced7e3c1f9c912dca5751664c86a7587b58b0854
The study results are also consistent with the results of previous studies, in which the researchers found that SHS exposure significantly reduced neonate’s birth weight [27,34,37,49].
result
4. Discussion
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In a previous work (17), we studied the tumor-immune system dynamics in the presence of effector T (TE) cells that can potentially reject or induce the rejection of the tumor, and TR cells, by formulating a simple mathematical model for the interaction between a solid tumor and the lymphocytes on its adjacent lymph nod...
background
2007, 179: 5659–5668.
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6ba8e09dba38051a4ce3a1584e628e88b55b2b0b
This approach – a kind of ‘Artificial Life route’ to self-organized criticality – could promote the development of conceptual models explaining how organisms are driven towards criticality in an abstract level, working as ‘proofs of concept’ (Barandiaran and Chemero, 2009) and supporting existing and future experimenta...
result
Introduction
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Other studies have found that GAD patients have a lower level of peripheral benzodiazepine receptors on their T lymphocytes [36], suggesting that benzodiazepines (which are antianxiety drugs) may also exert a regulatory effect on immune function [37].
result
1. Introduction
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9330745141a45a83044185911a9869cc77b04003
The existence of bona fide human naive pluripotent stem cells remains controversial, although various methods have been reported for maintaining hPSCs in states similar to those of mESCs (Hanna et al., 2010; Gafni et al., 2013; Chan et al., 2013; Takashima et al., 2014; Theunissen et al., 2014; Valamehr et al., 2014; W...
background
DISCUSSION
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46d8cc36dbf30b274aa7edbd36ed319556ea8047
…(Buttle et al., 2006), and there are many examples of studies examining the adoption of mobile technology and mobile services (Balocco et al., 2009; Kim and Garrison, 2009; Liang et al., 2007), to the best of the authors’ knowledge, this is the first study to combine these two perspectives in an…
background
1. Introduction
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Pubertal stage was scored by trained nurses according to Tanner (24,25) as a means of controlling for differences among children in maturational development not captured in reference growth curves for BMI (26).
method
Methods
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892c3a128a8fe3ebc58044464132a51d44e6117d
evolutionary transitions between different levels of carnivore sociality as well as insights into the mechanisms driving social evolution in general (Schneider and Kappeler 2014).
background
Introduction
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1fd9bb3fda0dae1ee2d5495072456b6c64f3fdc2
br A recent work (Bhuiyan et al., 2004) in the SCNT bovine field demonstrated that transfected ear fibroblasts were less able to develop to the blastocyst stage than their non-transfected counterpart, regardless of passage number (early or late). More likely, discrepancies among results reported up to now are due to di...
background
39aca52b748a1e8969413295fc736ea90fd930ea
b7c9b2632ffbcef4a35a6bf0c85686d9f11c1532
However, one of the above studies included both not on ART and ART-experienced patients [17] and also was a secondary data analysis of 642 patients.
result
Discussion
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2c787f88f00505152dac80505711d811b98e68e4
The methods working directly on the count data can be broadly divided into parametric (baySeq [14], EBSeq [24], ShrinkSeq [27], edgeR [23], DESeq [7], NBPSeq [15] and TSPM [13]) and non-parametric methods (NOISeq [25] and SAMseq [26]).
method
Methods
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62f8a69c7e3809949dd023852e0e0a54c49eaf74
A key in vitro finding was the increased release of cytochrome c, the molecular initiator of intrinsic apoptosis in many cancer cell lines, including: non-small cell lung carcinoma (H460) [16,17], squamous cell lung carcinoma (CH27) [18], hepatocellular carcinoma (HepG2, HCCM, and Hep3B) [24], nasopharyngeal carcinoma ...
background
4. Discussion
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0128715c48c0cf97a80c0aa7b339f13888708931
Intradural xtramedullary metastatic lesions associated with primary tumors riginating outside the neuroaxis are uncommon, occurring in 5% of ll spinal metastasis [3].
background
365727bf4eebb774f1f0e86f420c8b6ee8caeb77
6df9cfbb8925634a398a798179aacbf70c566f1b
delayed in monoamine oxidase A-deficient (Tg8) neonatal mice that display high 5-HT levels in the CNS (Cazalets et al., 2000).
background
Introduction
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4d7306d6200d68d8b18a331837efef26ef5e034c
The LDA parameters were estimated through variational Bayesian inference as described in Blei et al. (Blei, Ng, and Jordan 2003).
method
Methods
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1e56ed3d2c855f848ffd91baa90f661772a279e1
DBL1 (3D7 and 7G8), DBL1+2 FCR3, DBL2 FCR3, DBL3 (FCR3) and DBL5 (FCR3) were coupled at 1 mg/million microspheres [24]; FV2 was coupled at 3 mg protein/million microspheres based on previous optimization studies [23].
method
Methods
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8b7b5fd215bb18675843a3de788339ddda2981cd
However, CVP2 has higher catalytic activity than CVL1 in vitro and the cvp2 mutant shows early termination of vascular elongation, while the cvl1 mutant resembles wild type, suggesting an unequal redundancy in which CVP2 plays a more significant role in PtdIns(4,5)P2 degradation and PtdIns(4)P production (Carland and N...
background
CVL1/CVP2
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The above equation is the starting point of absolute perspective pose estimation [8, 14, 13, 9]: given a set of 3D–2D point correspondences (xi ↔ Xi), one can recover the 3D rigid body transformation (R, t) : W → C acting between the world coordinate frame W and the camera coordinate frame C.
background
2. Perspective Projection of Lines
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The C2 motif contains the core sequence LXLXL, which is also present in the EAR repressor motif (Jin et al. 2000; Aharoni et al. 2001).
background
VvMYB4‑like is localized to the nucleus
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It should be recognized nevertheless that the previously proposed formation and decay times of this hKL intermediate (Dioumaev and Braiman, 1997a) are now concluded to have been incorrect.
result
DISCUSSION
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Dissociative conscious sedation as a method with the characteristics of maintaining spontaneous ventilation, patient cooperation, patient comfort and enough amnesia has been reported in 2011 [17].
method
Background
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b15ccdb7254f9112bba41969c45b0ddcad9fa6bf
The problem of maximizing the amount of data transmitted up to a certain point is considered in [29, 46, 77, 94].
background
4.1 Introduction
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620a12113f0ae1f687dfcf6da5abbe6d3491fa85
Among them, HWP1 and ALS3 encode adhesins and are activated by the transcriptional regulator Efg1 during hyphal formation (Argimón et al. 2007).
background
Results
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3dee3e066677c54655543ebd4e7fefac427f5dfe
Studies have shown that hyperuricemia could accelerate renal disease in the remnant kidney model and cyclosporine nephropathy [4, 7, 8].
background
INTRODUCTION
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230ebe13b29d05e9c1ef6aede264ee108eb64592
By taking a qualitative approach to this part of the study and targeting registered nurses with appropriate experiences the study’s credibility was strengthened (Gabrielle et al. 2008).
background
Methods
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58c231934cba96039a7ac8cb84ee116a818b57e2
Although CD5 is a transmembrane molecule, a soluble form of human CD5 (shCD5) can be generated in activated T lymphocytes as a result of proteolytic cleavage [18].
background
Introduction
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The downregulation of IL-12 and TNF-α by atRA could further redirect the immune balance toward immunoglobulin production and a humoral immune response as suggested by the studies in vitamin A deficient mice (53, 54) and the increased susceptibility of vitamin A deficient children to measles (7, 55).
background
DISCUSSION
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6df615b3c555ee61dee9fa6079f905466ed2fb8f
First, correlational and principal components analyses were used to examine the relationship between TVA parameters and performance on the Fixed and Ran- dom versions of the SART (Robertson et al., 1997).
method
Method
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984344af43b460684730eb1ad65624e1c78946aa
Previous studies have also shown that lower levels of BDNF were associated with lower levels of NPY in both rat brain and cultured neurons (Barnea and Roberts, 2001; Nawa et al., 1993, 1994).
result
DISCUSSION
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a3b7aec5548fa4aa010b72231659fcf0e57c6087
Our participants had performed the movements only twice during the intervention epoch while in the ‘expert’ studies participants had experienced motor training over years (Calvo-Merino et al., 2005, 2006; Haslinger et al., 2005), several days (Reithler et al., 2007) or weeks (Cross et al., 2006).
result
Discussion
b7d6f3c1e7bef793823e8a9566689fc579e9e3e1
100747c07fdb0ba17e32f0c4fa29392cfd25482a
…for comparing VBM pre-processing algorithms besides comparison to empirically derived information we report a qualitative comparison of our findings with well-established anatomical distribution patterns associated with AD pathology (Braak and Braak, 1991; Frisoni et al., 2010; Hyman et al., 1997).
result
INTRODUCTION
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06e8eab4c7673fe38fd7dfea8879712a71e3a537
Experiments on standard testbed videos demonstrate that our algorithm possesses comparable or superior performance comparing to the state-of-the-art approaches designed for specific applications [11, 9, 17, 18, 5, 13].
background
5. Outlook and discussion
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As TIMP-1 functions not only as a MMP-8 inhibitor, but also exerts proinflammatory and growth factor –like characteristics, it may promote inflammation and atherogenesis [19, 20].
background
Discussion
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e99fd9775ae760a58cc0b1492b1d07e7a5006b78
Starting from this point, practically all free arachidonic acid that still remained in the medium and in the cells became complexed by serum albumin present in the medium (Dymkowska et al., 2006).
background
RESULTS
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cb101cdbe7aac08d64577ea4ec526d1663a9899d
Similar results were also observed by Potter et al. (1996) and Balmir et al. (1996) who reported that weaning hamsters consumed 6 to 7.5 gm of food daily that contained isolated soy protein.
result
DISCUSSION
c9eb6d338032128baef61e471255ef96fc4f3d7a
None
These results along with that reported by others [19,20] using error corrective feedback support KramerJohansen et al.
result
Discussion
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672549d8f166d0a33f63281546e7d7353e218bda
…et al., 2011), in the virulence of some bacteria like extraintestinal pathogenic E. coli strains, Edwardsiella tarda, or Salmonella typhimurium and plays a role in the biosynthesis of antibiotic and toxins (Dang et al., 2011; Garcie et al., 2016; Verbrugghe et al., 2015; Vivien et al., 2005).
background
INTRODUCTION
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4d00efd6ac1167944c2a39f4c17a43e0509f60cf
The loss of white matter following injury might be the result of the retraction or degeneration of injured descending fibres (Schwab and Bartholdi 1996), although this typically occurs over only short distances (Schnell and Schwab 1993) and therefore probably does not explain the loss seen in the present study.
background
Discussion
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9d66d06d2810f2c1966359a0df2cd6def9fa2c7d
The location of this plasticity is also consistent with previous functional imaging research showing cross-modal activity for visual motion stimuli in the right PTR (Cardin et al., 2013; Dewey and Hartley, 2015; Fine et al., 2005; Finney et al., 2001; Petitto et al., 2000; Sadato et al., 2005; Shiell et al., 2015a).
result
4. Discussion
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5de0d612db99d972950c5aa0fff1f27d14445035
The partial mitochondrial control region (domains I and II) was amplified and sequenced as described in Kvist et al. (1999, 2003).
method
Methods
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8c80dec6666f7941df992319c0c679eae3faff0a
ADAM8 expression in the thymus has previously been described [7,8,9,10,12,13].
background
Discussion
1d8d960f4c1bcd5fa93039b0d2f7e8c82e2b4d6f
f079647502ea163587ef3b85719bf50dbf9c36ed
The colocalization of VGLUT2 with Cu terminals in the CN shown in this study confirms that the Cu pathway to the CN is glutamatergic and demonstrates that Cu projections, like those from Sp5 and the contralateral CN (Zhou et al., 2010) use VGLUT2 to mediate glutamate transport at both MF and SB terminal endings.
background
DISCUSSION
b0d4b3642acafecd9c073d9e3c9fb9b5793a1262
7f245e59cfd419b97cc54729bd733cc86af51978
For example, because coral mucus provides an important carbon source for coral-associated bacteria (Ferrier-Pages et al. 2000; Brown and Bythell 2005; Wegley et al. 2007; Allers et al. 2008; Kimes et al. 2010), changes in production rates of mucus due to abiotic factors (e.
background
The role of coral-associated bacteria
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Significant inhibition of CaM kinase II activity has been observed in many models of delayed neuronal cell death including whole animal models of ischemia (Taft et al., 1988; Churn et al., 1990b, 1992a; Zivin et al., 1991; Aronowski et al., 1992) and glutamate excitotoxicity in neuronal cultures (Churn et al.
method
ec6f66952e6131e4249c4eac9984e8e0d237b6e1
315c54b1c8d06aabde569be83c9b033f77a12628
These results support the previous study in the M. fascicularis (Ruiz-Herrera et al., 2002a), where 51.14% of chromosome bands where ITSs are located express aphidicolin-induced fragile sites.
result
DISCUSSION
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321c03aa26a2d121863a96a5b88f4a443c53a500
Survivors noticed cognitive changes during and after chemotherapy treatment [35].
background
Results
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[KOOS], pedometry studies, and gait analyses) [8, 10, 15, 23, 30], and cost-to-utility (ie, cost-to-quality adjusted lifeyears) [21, 22, 26].
background
Introduction
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c14837c7f03add6100f1058023469212e4429452
However, consistent with previous reports [24], IFN-γ was undetectable in PEL lines, suggesting this is not a contributing mechanism.
result
DISCUSSION
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Our results are in agreement with the findings by Roger (1995), although his work was done in rice production systems and with different legume species.
result
Discussion
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study reaches = 10) to perform a depletion removal study to estimate actual abundance of Okaloosa darters (Dorazio et al. 2005) and evaluate accuracy of visual surveys.
method
Methods
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For neuronal differentiation of the neurospheres, they were partially dissociated as above and seeded on polylysine/ laminin-coated coverslips in neurogenic medium containing DMEM/F12 (1:1), B27 supplement (1:50, Invitrogen,USA), glutamine 2 mM, 50 U/ml penicillin, 50 μg/ml streptomycin, and 10 ng/ml mNGF (Alomone), as...
method
Methods
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a1db8daefe409a9736469f176031ea064361e911
nanotubes may be released intentionally in the future, as they are been explored for remediation and water cleaning purposes [33-38].
background
Methods
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52f78db083b803af0dc4a67bf2395369bf2747c0
This is consistent with reports that miR-155 is downstream of several molecules necessary for induction of the M1 phenotype, such as TLRs [50] or Akt2 activity [51].
result
4. Discussion
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This protective effect of FGF21 against obesity is consistent with the results of a previous report using DIO mice((30,31)).
result
Discussion
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3900019a35fa424f182a2e913cc3c121832f721a
These results are consistent with preclinical studies showing binding to both D3 and D2 receptors in vivo (Gyertyán et al. 2011) and preferential binding to D3 receptors in vitro (Kiss et al. 2010) as well as PET studies in nonhuman primates (Seneca et al. 2011; Toth et al. 2013) and humans (Keator…
result
Discussion
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However, neither IL-4 nor IL-13 plays a consistently suppressive role; their effects appear model and/or Leishmania species dependent (22, 23, 27, 30, 31, 49, 53, 56, 57).
background
DISCUSSION
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86de5a183907a9c302336418ffbc833c59fc8be0
132 outflow from the superficial towards the deep system, several studies[6,7,11] have suggested that the absence of direct communications between the SIEV and the DIEV through venous perforators could favor congestion.
background
410376c6a35d3dd09a544e0b334ac4e11e22da52
bc09dfbd0300f89c727c3b5f494b326fc0bb9b15
Typically, case studies combine data collection techniques such as interviews, observation, questionnaires, and document and text analysis (Darke, Shanks & Broadbent, 1998).
background
3. Methodology
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fumigatus encodes two transcription factors, hapX and sreA, that maintain iron homeostasis whereby hapX represses sreA expression and subsequently ironconsuming pathways, and activates siderophore biosynthesis during iron-starvation, while sreA represses hapX during iron-sufficient conditions in a negative feedback loo...
background
Discussion
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The two focused ultrasound beams A and B are excited at the same source pressure and at the angular frequencies xa = x0 Dx/2 and xb = x0 + Dx/2, where x0 = 2pf0 and Dx are the center and modulation angular frequencies, respectively, such that Dx x0 (f0 being the center frequency) [3,4,11].
background
2. Theoretical formulation
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These results might be interpreted based on the previous observations that testosterone supplementation can decrease total cholesterol levels without affecting HDL-cholesterol levels (53,55).
background
RESULTS
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Although other metabolic engineering efforts in amino acid metabolism such as over expressing glutamine synthetase and glutamate synthase resulted in improved total free amino acids and growth phenotypes in transgenic plants (Ameziane et al., 2000; Migge et al., 2000; Chichkova et al., 2001; Fuentes et al., 2001; Olive...
background
Discussion
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75edacebaae1ad61972d0aa878d738cb81fc87b8
The findings in literature, confirmed by the results obtained in this study, relate significantly low self-confidence in the possibility to stop smoking [31–33] and low adherence to therapeutic program [3, 24, 34] with failure in therapy.
result
4. Discussion
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[77] found that TGF-ß induced apoptosis in KATO-III but not in other cell lines, such as MKN-l, MKN-28, MKN-45,
background
4118d21a5a09a31994a63d4d6fcff521855a0ea7
d82369cdf3bf31e1fc1231e0705c1768930d0d5c
2002) and mice lacking the placenta-specific Igf2 transcript show IUGRaswell as placentas that are small and have altered nutrient transport (Constância et al. 2002; Sibley et al. 2004; Sferruzzi-Perri et al. 2011).
background
Structure and function of the placenta
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Sixth, patients are simply not interested [4], but it is not clear whether patients are not interested in the telehealth intervention or the research itself.
background
Background
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e817ae639ba2aab62172146638a78a84f8736de1
While it is clear that it increases progression-free survival in high grade tumors, the literature is mixed on overall survival [4-5, 10, 25].
background
Discussion
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9ba74eb8a48a70bacc10f3da976ae4f3d104bca6
We compare KCDML not only with the state-of-art methods including our current work—CDML [38], Huang's method [43] and PCA combined with RBF (PCA-RBF) [43], but also with important baseline methods, such as PCA Kernel PCA (KPCA), LPP, Kernel LPP (KLPP) [44] and LDA.
method
4. Experiments
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Hepatic glucose production and glucose disposal rate were calculated for the basal period and the steady-state portion of the glucose clamp using the Steele equation for steady-state conditions (23).
method
Methods
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18e212a039557ede65ffc4b17fd9dfe4143ce491
Adequate empiric antimicrobial treatment was defined as antibiotic therapy administered within 24 hours after blood culture samples were obtained which the microorganism was susceptible [16].
method
Methods
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The types of complex genetic interactions between duplicated homeologous loci which are possible after polyploidization are best documented in plants, where allopolyploidy in particular is a pervasive phenomenon (Otto and Whitton 2000; Wendel 2000; Doyle and Egan 2010).
background
Discussion
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This is a standard way of assessing relative competitive ability (Santos et al. 1992; Fellowes et al. 1998).
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1. INTRODUCTION
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In the rest of the article, the discussed protocols already possess the aforementioned characteristics, as elaborated by the MANET WG in [3].
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2.2.1 MANET Routing Issues and Evaluation Considerations (RFC 2501)
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Wolff (1996) obtained similar results, although in previous works (Wolff et al., 1995) no differences between cultivars were detected.
result
Discussion
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The major route of excretion in mammals is via the urine (Hawkins et al. 1980; Klos and Dekant 1994; Hissink et al. 1996, 1997), and the main metabolite of p-DCB is 2,5-DCP, which is excreted both as the free substance and in conjugated forms (as sulfate or glucuronide) in the urine (Azouz et al.…
background
Introduction
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All 7 transabdominal ultrasound studies [24,27,57–61] 11 of 22 [28,30,41–44,48,50–52,55] EUS studies used contrast enhancement.
method
3.5. Ultrasound
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To date, CSC markers of endometrial cancer have been identified, including CD133, CD44 and ALDH1 [7, 22, 35, 36].
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Discussion
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Further, fruiting patterns vary seasonally and geographically in the eastern humid forests of Madagascar (Ganzhorn et al., 1999; Johnson, 2002; Overdorff, 1996).
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DISCUSSION
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This is in accordance with the results of previously published studies (Gruber and Gollhofer 2004; Bruhn et al. 2006; Gruber et al. 2007a).
result
Discussion
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2% of cases.(15) Further, the VTE detection rates reported here are also in line with large data sets from National (Nationwide) Inpatient Sample database reporting on results of benign brain tumor resection, making it likely that our results are valid in other clinical settings as well.
result
DISCUSSION
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This has been demonstrated for neural sources that are known to be highly correlated, such as bilateral activation of the temporal lobes during steady-state auditory stimulation (Brookes et al., 2007; Dalal et al., 2006; Popescu et al., 2008; Quraan and Cheyne, 2008; Quraan and Cheyne, 2010), and for primary visual sou...
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1. Introduction
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Some parts of the map by Poutsma et al. (2008) are inaccurate, because they are based on previously published verbal descriptions.
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Introduction
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Youth with disabilities have to face more complex challenges during this transition phase compared to their able-bodied counterparts when striving to fulfil age-appropriate roles and participate in their communities [5, 6].
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Introduction
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The observed decrease of the CFF/FUF in our HE patients is well in line with the results of Kircheis et al. (2001a, 2001b, 2001c, 2002) and Timmermann et al. (2008).
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4.1. CFF, FUF and clinical parameters
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Resting-state corticostriatal functional connectivity is correlated with executive performance in both healthy subjects and in diseases such as schizophrenia, Huntington’s disease and ADHD (Mennes et al., 2011; Unschuld et al., 2012; Su et al., 2013; Gordon et al., 2015).
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Discussion
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Several investigators (18, 19, 43) have shown that endogenous female reproductive hormone status alters the control of a variety of thermoregulatory effectors.
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In patients with insulin resistance, production of NH3 from proximal tubules is reduced and ammonia excretion is also reduced accordingly, resulting in low urine pH.[27] In addition, in patients with insulin resistance, sodium absorption is increased because of hyperinsulinemia, which also lowers urine pH.
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DISCUSSION
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Anti-Flik interference experiments have further supported the idea that Flick protein is an endogenous antagonist of ventralising signals (Towers et al., 1999).
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Discussion
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Previous reports on gene therapy for ovarian and other similar cancer cell lines have shown an increase in infectivity through CAR-independent transduction, achieving higher reporter gene expression by several orders of magnitude in the primary tumor cells (Dmitriev et al., 1998; Kasono et al., 1999; Vanderkwaak et al....
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Introduction
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As a result, a preliminary version of the Q-SEA instrument has previously been published [10].
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Discussion
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Concentrations of human CRP increase up to 1000-fold within 24–48 h of tissue injury and represent a sensitive, but a nonspecific marker of inflammation [17].
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To study the role of top-down modulation on speech in noise perception, de Boer and Thornton (2008) examined MOCB activity in young participants who underwent a training program to discriminate speech presented in noisy environments (de Boer & Thornton, 2008).
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Introduction
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Additionally, as previously shown [22], disruption of the HIR complex in a strain carrying a deletion of HPC2 (hpc2D) also prevented recruitment of SWI/SNF to HTA1-HTB1 (Figure 4A, compare hpc2D and WT).
method
Results
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Resistance to number of antimicrobial agents among a variety of clinically significant species of bacteria is becoming increasingly important global problem [4].
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1. Introduction
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In this study, we used 2iL medium plus a PKC inhibitor, forskolin, and a TGF-b inhibitor for conversion and maintenance because some reports have suggested that a PKC inhibitor and forskolin facilitate conversion from the primed to the naive state (Hanna et al., 2010; Dutta et al., 2011; Takashima et al., 2014; Duggal ...
method
DISCUSSION
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%) fallow deer were positive to A. phagocytophylum DNA, however a work recently conducted by Michalik et al. (2009) on a population of 44 fallow deer living in West–Central Poland using only a PCR approach, showed a prevalence rate (20.5
result
4. Discussion
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Signals inspector such as oscilloscope, image processing library such as OpenCV, pattern matching algorithm (Dynamic Time Warping [9], five degrees-offreedom gesture recognition) are integrated and ready-to-use to support that informal design technique.
method
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