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Online versions of such sparse GPs [11, 12, 13] have produced a viable alternative for real-time model learning problems [14].
background
1 Introduction
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As mentioned above, under stressful conditions, IR might sequentially activate the ER stress receptors, thereby triggering ER stress-induced cell death signaling: for example, PERK, one of the ER stress receptors, might phosphorylate eIF2α, which translocated ATF4 into nucleus, and then increased the gene transcription...
background
4. Discussion
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Consistent with previous characterizations, these neurons respond only to vestibular stimulation and are insensitive to eye movements (Roy and Cullen, 2001b, 2004, Sadeghi et al., 2011).
method
METHODS
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cc09afc875a142890eb534592bc552a1e0a891f1
This is inconsistent with the results of a previous study of the spatial heterogeneity of nutrients: nutrient heterogeneity affected the growth of large plants but did not affect that of small plants (Maestre and Reynolds 2006).
result
Discussion
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379ad1c4c0840e7ca384d6487a4f0d2838f813dc
PCV-1 was first detected as a contaminant of the porcine kidney PK-15 cell line [4] whereas PCV-2 has been associated with postweaning multisystemic wasting syndrome (PMWS) [5, 6], porcine dermatitis and nephropathy syndrome (PDNS) [7], proliferative necrotizing pneumonia [8], and reproductive disorders [9], all of the...
background
6d4a3d1350f6062c417768103618a35cce03fbe1
ba48bada819d48db87bb2c98aebc52985b8e1aa4
Lens removal (Tigges et al., 1992) and atropine instillation (Hendrickson et al., 1987) also produce this pattern.
background
RESULTS
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b2953028f52723af59934b44c0958c1a3af276a8
Replacing behaviors associated with a low energy expenditure by just 10 min of MVPA per day can have a significant impact on health outcomes such as obesity [16, 24].
method
Discussion
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26e3231050045c392eb982c52747c0cf1c3a90ec
We assume the remote system has a complex classifier f0, in our experiments 500 gradient boosted trees using XGBoost [4].
method
5 Experiments
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26bc9195c6343e4d7f434dd65b4ad67efe2be27a
Though we would eventually like to include a discovery module in our implementation that assembles the required knowledge bases dynamically by identifying suitable content on the semantic Web, for example, through the automatic generation of queries issued to semantic repositories such as Bio2RDF [15, 16] and DBpedia [...
method
Implementation
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However, from that data we can not draw any conclusions regarding the relationship between public and See Takalo (2012) for a survey on public innovation policies.
background
73c35204479133cd6d96a14b73aab40e33875c9e
358db60d93a8530bed257b981b07bfbf37f925e3
1.5 Variant annotation We used the ANNOVAR [10] tool (version 2013-02-21) to annotate SNPs and indels.
method
1 Methods
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6e00f7980c4efc55ba76efdccebc6411f054a7da
However, from that data we can not draw any conclusions regarding the relationship between public and 1See Takalo (2012) for a survey on public innovation policies.
background
1 Introduction
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358db60d93a8530bed257b981b07bfbf37f925e3
Sijen et al. (2001) described silencing of the endogenous dfrA promoter in Petunia.
background
Discussion
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1504de3540a465ef14d49897e9506fae51902f2e
[24] showed that the above optimization can be performed efficiently by sorting the samples xk in descending order of the score w ψ(xk).
method
2.2 AP-SVM
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Previously, a phosphoproteomic study demonstrated that AbfR1 is phosphorylated in vivo at a tyrosine and serine residue, Y84 and S87 (Reimann et al., 2013).
background
RESULTS
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f4d9d6e1e243f66a3009acafa8d7b0d13254f488
, 1991) and have a lower OX1 expression than haematogenously derived cells (Sedgwick et al., 1991).
background
4. Discussion
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1959ef6015c3098b4bd4fa6ee8b76479fad3a390
Based on the Born method, aggregation measurements provide an aggregation index curve describing the light transmission intensity changes of the PRP samples (15, 64).
method
Methodology
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bb717310d12d5e901a4f615b04d1ee38966856a7
(E) Sensorgram for FLNA(16-23) binding kinetics to immobilized ICL3 peptide as in D.
method
Figure legends
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We administered the Conflict Resolution Style Inventory (CRSI; Kurdek, 1994) [40] to measure adolescents’ style of handling conflicts in the current romantic relationship.
method
Methods
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…Spire1C KIND domain decreases ER-mitochondria overlaps Since ER tubules have been implicated in mitochondrial constriction and division (Friedman et al., 2011; Korobova et al., 2013; Murley et al., 2013; Korobova et al., 2014), we investigated whether Spire1C influences ER-mitochondria association.
background
Results
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Similar N-acylation of the acetamide and/or N, N-diacyl substitutions were previously reported for the acylation of chitosan [16] and chitin [5, 9].
background
2. Results and Discussion
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Expression values were extracted using two model-based expression indexes as implemented in the dChip package (Li and Wong, 2001a) using default parameters and normalization.
method
METHODS
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To assess whether distractor size manipulations also affected hand transport control, the maximum tangential velocity of the wrist marker in the plane of the work surface, a conventional and sensitive index of hand transport was also calculated (Gentilucci et al. 1991; Jakobson and Goodale 1991).
background
Methods
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In this chapter, we focus on the use of two-photon laser scanning microscopy, which has enabled the monitoring of hundreds of individual neurons in anesthetized (26), awake and behaving animals (9, 11, 27, 28) as well as neurotransmitter uncaging at the level of individual dendritic spines (29, 30) or at many discrete ...
background
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41129a35ce2f54686e6a9c697a4ab9d6b0312150
[23] emphasized the memorability of phrases, and proposed a method for sampling memorable and representative phrase sets based on a multiple regression model.
method
Phrase Sets for Text Entry Experiments
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These results suggest that H2O2 was not involved in the osmotic stress-ethylene production, which is inconsistent to the results described by Watanabe and Sakai (1998) in winter squash (Cucurbita maxima), who suggested H2O2 would be involve to the expression of gene for a would-inducible 1-…
result
Discussion
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The inhibition of down-regulation of HMGA2 by gene knockdown of unrelated ALKs based on the current signaling model [4–7] may be indirect effect, because gene expression was examined at 24 h after ligand stimulation.
background
e9f05bfe64168341ef92877de83b6d054ab6bfc5
16ec74d99263859efd3ee5d2010d40ff16133847
Contrary to our finding, the association of long intervals and pregnancy complications, such as pre-eclampsia, preterm birth and SGA,were also reported in some studies.4,7 Conflicting results may be due to lack of standardized definitions used for IPI.
result
Discussion
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36abe0ba3c5932ee3890052e9c8c7edcd25729a2
[12] At neuroimaging, venous hypertension and cerebral edema caused by straight sinus thrombosis typically result in high signal intensity in the bilateral thalami and basal ganglia.[1,6] In the present case, FLAIR showed characteristic hyperintensity in the bilateral basal ganglia and thalami as mentioned above.
background
DISCUSSION
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8ec5dbce8df62233e9ad3fc70cd5c39c754373b7
The reviewed articles also addressed e-health readiness assessment from varying perspectives, such as electronic medical records,(18) telemedicine,(14) rural communities,(13,14,21) or developing countries.(3,10,11,19) Discussion
background
78abc60ce5f366fd4a9b2e3f5c380cdda3b94001
279dd34bd081585ab9fe9763357b51ce68f6f4ca
Breese et al. (1998) present a number of different algorithms for collaborative filtering, including two Bayesian approaches.
method
4 Experiments
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0fcc45600283abca12ea2f422e3fb2575f4c7fc0
1; and Slobounov et al. 1997, 1998; Haibach et al. 2007; Slobounov et al. 2008 for details).
background
Methods
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7b1b2dc942a927d8885aafe37f997907bad0d4d9
However, this resistance to drought is much lower than observed for many Pulmonates which may survive several months or even more to the desiccation (Barbosa and Barbosa 1959; Cridland 1967; Véra et al. 1994).
background
Discussion
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fcfec539f46daee1294acc8344e14f90a2d67bda
Consistent with previous studies [19] and guidelines and recommendation for weight loss [26-28], our results showed that most of the GPs gave advice on lifestyle, dietary and physical activity.
result
Discussion
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Our finding is consistent with other studies which have also highlighted the involvement of this novel molecule, Ara-LAM, in inducing proinflammatory responses (IL-8, TNF-a) in macrophages via interacting with TLR-2 [26,27].
result
29fe703c3f5bc0e023f948e92c0ecc5b54df928f
45deba2e2ac79e34a41d90ecb706310c7c3d6fd0
A comparison of the chemical structures of equol and estradiol (Setchell et al. 1984).
background
659d04fc6cec396172261746c9ae805725eabe9f
599f8f76f1e2c7dd6016d87b3255e1d82649d35c
Lamotrigine monotherapy (50–200 mg daily) was also reported to be superior to placebo in the treatment of nonrapid cycling bipolar I depression in adults and uncontrolled observations have suggested possible antimanic [19,20], antidepressant [21], and anticycling/mood stabilization properties [13,19,22].
background
Introduction
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03cd9870ab3eff6fe1afcc2ec502ef2b979d828c
Size information from the centered and oriented outlines was removed with a uniform scaling of the pseudolandmark configurations to unit centroid size (Benazzi et al., 2011a, b, 2012).
method
Methods
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7e7a117918005eed0b7ae4e907e8bfdd1bc95471
ation (birth weight, head circumference, crown-heel length, standards of fetal growth according to Lubchenco et al.(6)), and vertical transmission of HIV-1 were determined.
method
METHOD
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These models are the radial-modesof-vibration model of Abdullah (1966), the tornado/ boundary interaction model of Tatom et al.
method
5. A comparison with sound generation models
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5 mg), GST-53BP2(715-1005) (1 mg), GST-GL(1-257) (1 mg), and GSTGL(94–257) (1 mg) were separated on duplicate SDS–12.
background
f92ee4af334b6218ccc8dcc45bcc96af59c190a6
aa3d7a72f3ad9fd00cb9b8e683968489cff824cd
Lysine propionylation was recently shown to be abundant in T. thermophilus, an extremely thermophilic Gram-negative bacterium that belongs to the Deinococcus–Thermus phylum (Okanishi et al. 2014).
background
Identification of lysine propionylation in five bacteria
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Although the measured values are below the toxic level (Lau and Wong 2000), one should wonder what consequences may derive from an ongoing intake of food packaged in plastic material.
background
Discussion
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14665674e2db3e3b7b16ebe7ecab87bfdf7c0e41
Normal FEV1/FVC was defined based on the NHANES III database and the ATS guidelines as values greater than 95% of the predicted for age, gender, and height [1, 10].
method
2. Methods
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6320207a0ffe8c77c7544073f6a66d2e675b4c7e
For reference we also include in Table III the results for the scalar field toy model with pure initial data (the s = 0 case) [21,22] (the results for generic initial data coincide with those of gravitational and electromagnetic perturbations).
result
VI. SUMMARY AND PHYSICAL IMPLICATIONS
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None
50 per extra sample in the pooling strategy to account for personnel time and collection container costs (S1 Text) [6].
background
Methods
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9b37a27c98bd6b54333e1f2e7134c2fe513c91f4
When X(D) ∼ N(μD, σ(2)), the two criteria will have the same optimum, that is, xJ = xC, but the variance of the non-parametric cut-point estimator optimizing the Youden index may be much larger than that of the concordance probability optimizer, Var ( x̂J ) > Var ( x̂C ) [6].
background
930142f95ef0a462824f9c9274d55cead07babfa
9e9ec0f025d0f1b6a265b7f25d9a81ff8538b7ed
There are many studies where CC and cerebral hemisphere widths and areas have been measured on MR images.[13-19]
background
Statistical Analysis
7b0b62a2ff2d9bfeab29a55cb55cf04ffdbcd1fe
21e6307b3723d70218670aed0ab1bcae8c7311e8
6 shows that if state converges in finite time to the EP, then also the output converges in finite time to the corresponding OEP, however Example 2 in [22] give the conclusion that state converges in fintie time to the EP, but the output does not converge in finite time to the OEP.
background
3.3 Convergence in finite time
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Since then, 164 independent gene losses would have occurred in the lineages, leading to the three present genomes (39).
background
DISCUSSION
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b817e1a30498e4341747aa99552f3ea94adc10e1
Merkel cell virus has been linked to Merkel carcinoma [8] and Fusobacterium has recently been associated with colorectal carcinoma [6].
background
Introduction
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e1cd0d8f4a0dd146e2ea02e3a4a129a2736dac66
Indeed, daily patterns of Epas1 mRNA is rhythmically expressed in the mouse heart with high levels at circadian time 8–12 (unpublished data), which precedes peak expression of mPai-1 mRNA (Minami et al., 2002; Oishi et al., 2005a).
background
4. Discussion
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This differs from the results of McNaughton (1979), which showed substantial re-growth in grasses after insect feeding.
result
Discussion
1e81ea4a19cc1c146526c92c0407675c565866c4
None
2012 (59) Two cohorts; n 7,740 and 4,564 Physical activity and television watching 32 BMI- and obesity-related variants Th e genetic eff ects on BMI were stronger in those with low physical activity or longer hours of television watching Ahmad S, et al.
background
0e523380606aff47d62390286a2b9f6cacab1459
fbff8d14a981000f20bfb7ec0d67f726ef9a634a
Iontophoretic transdermal deliveries of human insulin and thermoplastic pastes as depot upon cooling have also been tried [18,19].
background
INTRODUCTION
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34edb48da45c29c10e589f85cdcdb8e70202eb4f
In credit scoring, for instance, applying ensemble techniques can be very effective, but the model is often obliged to have “sound business logic”, that is, to be interpretable [10].
background
1 Introduction
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…that the approach makes it possible to foster a ‘shared responsibility between students and instructors’ (McLaughlin et al., 2014, p. 242), and overall, optimising classroom time is often specifically emphasised (Gannod et al., 2008; Mason et al., 2013; McLaughlin et al., 2014; Tucker, 2012).
background
Results
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12a23d19543e73b5808b35f1ff2d00faba633bb6
A recent storytelling task by Hendriks et al. (2014) confirmed this overall pattern but also highlighted that other factors can modulate this effect of the discourse stages. In the task used by Hendriks et al. (2014), participants were asked to tell picturebased stories featuring two characters of the same gender to a ...
background
INTRODUCTION
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5af4e6e8d6e7a25cb37a9d52e87a1f28b4464e04
In addition, education is likely to enhance female autonomy so that women develop greater confidence and capabilities to make decisions regarding their children’s health [39].
background
Discussion
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dbbda83849f2be46a60f90ce8b9abd2b18ed87f3
Another group reported that the 118T9 10 repeat was associated with higher reporter gene expression in HepG2 liver cells (Yamanaka et al., 2004), and this variant was recently linked to higher incidence toxicity and increased response to irinotecan in cancer patients.
background
17880, and RR-00054 from the National Institutes of Health (M.H.C, D.J.G.,
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d75ad368dded5e7d1a6ab96fe87a6fe7494f0673
These devices have also been clinically recommended for stabilization and modulation of the load distribution across mildly degenerated discs in an attempt to alleviate discogenic back pain and potentially enable regeneration of disc cells [22, 23].
background
1. Introduction
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d91350c15c4970b53aaeea14fb061c2af0611dd3
A more formal study of incidence and the histology of the tumors need to be done, but these results suggest thatMuSKantibodies are not so infrequent in Chinese as previously reported in a study from Taiwan [5].
result
4. Discussion
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…orogenic events have contributed to shaping the current diversity and distribution of modern species in both the Neotropical (Bush 1994; Hoorn et al. 1995, 2010; Pennington et al. 2004; Rull 2006, 2008, 2011; Antonelli & Sanmartin 2011) and temperate regions (Ruzzante et al. 2006,…
background
Results and discussion
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It is well-known that a single nick (SN) does not efficiently induce gene editing (Ran et al. 2013a; Davis and Maizels 2014).
background
A tandem nick (TN) in the genome induces efficient gene editing using a plasmid donor
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, ABA) mediate priming of guard cell Ca2þ sensors, such that they can respond to elevated cytosolic Ca2þ levels [63].
background
Results
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e7ae8d642c71cd6b0a96740b0fd502dfae564d04
Findings reported by Bryzgalova et al (194), suggesting reduced total GLUT4 levels in muscle as an underlying cause of the ER KO insulin resistance phenotype, were not supported by data from Ribas et al (192).
method
C. ER in the ventromedial hypothalamus and control of energy expenditure
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Beside SecuGen Hamster IV, other optical devices were used to collect the IIIT-D Multisensor Optical and Latent Fingerprint [25].
method
A. Optical sensor
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This corresponds to T191 of tobacco CYC3;3, a extremely conserved site important for full CYCD nuclear import (Menges et al. 2007).
background
Results
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da0746558cecaad6681c199c44b8ed7d128848e5
Aside from the effects on Th1 cells, IL-27 has recently reported that played a regulatory role in limiting excessive inflammation during infection with Toxoplasma gondii by modulating the development of Th17 cells (20, 21).
background
489a1ce077681e7614c79c4f3380050bc031c7fa
1e9bad5044514deb8e2c82c221c9dbc5007139c0
The Metropolis- Hastings algorithm [49] was used to estimate the posterior distributions for ancestral reconstructions and model parameters in a Markovchain Monte Carlo framework [29].
method
Methods
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143d2e02ab91ae6259576ac50b664b8647af8988
This assumption is confirmed by the different pattern of the expression of X linked genes in different parts of the same placenta: equally probable, mostly from one homolog, and fully monoallelic (Moreira de Mello et al., 2010).
background
RESULTS AND DISCUSSION
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The OHC lateral wall, where the motor elements are located [24,31], was modeled as a series mixture of passive ‘‘elastic’’ and active piezoelectric ‘‘motor’’ elements [29] to arrive at a composite constitutive model for the lateral wall.
background
Methods
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37e7ba41fa4f19d0d75e054276dafd86f2e90d28
Plan and goal recognition models have been devised for story understanding systems (Charniak and Goldman, 1993), productivity software (Horvitz, et al., 1998), intelligent tutoring systems (Conati, Gertner, and VanLehn, 2002), and dialogue systems (Blaylock and Allen, 2003).
background
1. Introduction
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a4cf4bb41fb0b6fa978fd1456e86308218c8e882
While Hutt and Longtin (2010) chose pi=pe, reflecting equal affinity of propofol for GABAA receptors located on cortical inhibitory and pyramidal neurons, we relax this assumption, thereby accounting for the possibly differential affinity of propofol for different neuron types.
background
Modeling the action of propofol
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[31], we check their validity in the case of charged Higgs boson production.
background
3.1 Settings
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1efb6d4b033492ec257f9b1c600915a09a368613
The Intercontinental Chemical Transport Experiment B (INTEX-B) aircraft campaign over the North Pacific and western coast of North America made measurements of OH and HO2 (Mao et al., 2009; Singh et al., 2009).
background
5a104aa1d96209f1d2a7df96b67c8b06f8cc691c
18bc8b07747174cbac2230f69e4d66800c0424e3
The results of behavioral analyses are consistent with published data reporting that the Ts65Dn mice show normal or hyperactive exploration in the open filed (Coussons-Read and Crnic, 1996; Martínez-Cué et al., 2002; Faizi et al., 2011; Incerti et al., 2011).
result
DISCUSSION
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000a4f645f4ee037db3df4f3aa0effb85922df19
The Swi1-Swi3 complex or its homologues are known to facilitate the loading of Mrc1 or Claspin onto chromatin (8, 41).
background
RESULTS
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To measure the effect of verb type on the observed QUDs, we used mixed-effect logistic regressions (Jaeger, 2008).
method
Methodology
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Similar to our results, concentrations of 3.15 ngmL 1, 31.5 ngmL 1 and 315 ngmL 1 of progesterone added during the culture phase of bovine in vitroproduced embryos did not impact on the proportion of zygotes reaching the blastocyst stage in a recent study (Clemente et al. 2009).
result
Discussion
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, 2012; Bergen et al., 2012) but also for studying children’s pragmatic abilities without implicitly assuming they have mastered challenging linguistic structures (Stiller et al., 2011). In this paper, we extend these results beyond simple reference games to full decision-problems in which the agents reason about langu...
method
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Data-centric storage (DCS) [24,27,42,56] provides in-network storage and query mechanisms for sensor networks.
background
1.2.3 Data-Centric Storage
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In addition, a new flgII-28 region distinct from flg22 in the flagellin of Pseudomonas syringae pv. tomato (Pst) has been recently characterized as a MAMP, which may be specifically recognized by Solanaceae species (Cai et al., 2011; Clarke et al., 2013).
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INTRODUCTION
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…recent reports have implicated CHH as a regulator of multiple physiological effects, which include reproduction (De Kleijn and Van Herp, 1998; Khayat et al., 1998), molting (Chung et al., 1999), osmoregulation (Serrano et al., 2003; Spanings-Pierrot et al., 2000), and lipid metabolism…
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INTRODUCTION
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IL7 and IL15 are IL-2 family cytokines regulating survival and activation of lymphocytes, and are of interest in MS research since they signal through the IL2- and IL7-receptors, which have shown strong association with MS in genome-wide association studies [31].
background
Discussion
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Our new scoring function estimates the penalty term from the data to make it consistent with the data, which is similar to the DIC (Deviance Information Criterion) score trying to identify models that best explain the observed data [30].
method
Methods
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Crystal structures of some theta GSTs have indicated that the GSH-binding site may be sited further inside the protein than in other classes of GST, and that conventional GSH-aYnity matrices may be unable to bind the active site (Hayes and Pulford, 1995).
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4.1. Cloning and sequence analysis of A. fumigatus GST open reading frames
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This is a particularly positive result as OASIS mainly serves the area of South London that is socioeconomically deprived, has a high proportion of ethnic minorities and an often difficult relationship between service users and mental health services (Broome et al. 2005).
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Discussion
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Other studies indicate that methyl salicylate (MeSA) azelaic acid (AA), glycerol-3-phospate (G3P)derived factor, and dehydroabietinal (DA) may also be SAR long distance signals (Park et al., 2007; Vlot et al., 2008; Jung et al., 2009; Chanda et al., 2011; Chaturvedi et al., 2012).
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INTRODUCTION
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In Marsupenaeus japonicas and Penaeus semisulcatus, the CHH from eyestalk is involved in the suppression of vitellogenin (Vg) gene expression (Khayat et al., 1998; Tsutsui et al., 2005).
background
DISCUSSION
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In this respect, we have recently shown that malignant transformation causes losses, gains, and imbalances in the expression of human MHC I and two antigen-processing gene products: the endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (13, 14).
background
Introduction
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In addition, differential hypertrophy occurs even within a single muscle along its length (Narici et al., 1989, 1996; Housh et al., 1992).
background
Introduction
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The resulting levels of ChE in plasma were in the same order of magnitude as those found by Winters et al. (1997) in control rabbits.
result
4. Discussion
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…impact on overall energy cost. the Ec of the uphill sections we found can be compared with the results of other studies (table 2). the lowest Ec (tosi et al. 2009) was described for a short section lasting only 8 min while that of races lasting 1–2 h (Duc et al. 2011) up to 6 h 45 (this…
result
Discussion
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Ruby [4, 10] goes one step further by making the syntax much more compact and simpler and also provides various built-in features that make the common tasks of text processing, creating and processing threads, web programming etc.
background
1. INTRODUCTION
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[31] with the same significance, we still find sufficient evidence that F = 4 is favourable in many
background
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Optimization We used three objective functions that were employed previously to study multi-finger prehension in human performers (Hershkovitz et al. 1995, 1997; Zatsiorsky et al. 2002b; Pataky et al. 2004a, b).
method
Methods
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We have proposed that the highly specialized EOM allotype is a consequence of a novel myoblast lineage interacting with extrinsic factors during a postnatal critical period of development (5, 7, 12, 57).
background
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Examples of possible modifiers include loci encoding xenobiotic enzymes, NAT1, NAT2, GSTM1, GSTT1 (7–9), or ATM, ataxia-telangiectasia-associated locus (10).
background
Introduction
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…a homologous exchange mutant of the Er. carotovora subsp. carotovora rpoS gene, the suicide vector pUT mini-Tn5 Cm was used. pUT mini-Tn5 Cm carries the λpir-dependent R6K ori, which does not replicate in bacteria that lack λpir, such as Er. carotovora subsp. carotovora (de Lorenzo & Timmis, 1994).
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METHODS
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