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PMC2041817_pntd-0000002-g007_14318.jpg
What is the focal point of this photograph?
Composite of mixed cellular infiltrates.Histological sections representative for four patients stained with antibodies against different cellular markers (counterstain haematoxylin). Magnifications at ×40 (A, E, G), ×100 (C, D, F, I, J), ×200 (Ainsert, B, H) or ×1000 (Einsert). (A) Only few scattered PMNL staining posi...
PMC2041817_pntd-0000002-g007_14321.jpg
What is shown in this image?
Composite of mixed cellular infiltrates.Histological sections representative for four patients stained with antibodies against different cellular markers (counterstain haematoxylin). Magnifications at ×40 (A, E, G), ×100 (C, D, F, I, J), ×200 (Ainsert, B, H) or ×1000 (Einsert). (A) Only few scattered PMNL staining posi...
PMC2041817_pntd-0000002-g007_14325.jpg
What is the central feature of this picture?
Composite of mixed cellular infiltrates.Histological sections representative for four patients stained with antibodies against different cellular markers (counterstain haematoxylin). Magnifications at ×40 (A, E, G), ×100 (C, D, F, I, J), ×200 (Ainsert, B, H) or ×1000 (Einsert). (A) Only few scattered PMNL staining posi...
PMC2041817_pntd-0000002-g008_14332.jpg
What is the principal component of this image?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14326.jpg
Can you identify the primary element in this image?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14330.jpg
What is the dominant medical problem in this image?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14328.jpg
What is the main focus of this visual representation?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14331.jpg
What stands out most in this visual?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14327.jpg
What's the most prominent thing you notice in this picture?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041817_pntd-0000002-g008_14329.jpg
What is shown in this image?
Follicle-like lymphocyte foci reveal organized cellular formation.Serial sections of a representative lymphocyte focus stained with HE (A; magnification ×40) or with antibodies against different cellular markers and haematoxylin as counterstain (B to I; magnification ×100). (A) Large aggregate of lymphocytes in the upp...
PMC2041950_F3_14335.jpg
What is the principal component of this image?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14337.jpg
What is the principal component of this image?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14336.jpg
What is being portrayed in this visual content?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14338.jpg
What key item or scene is captured in this photo?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14340.jpg
What is the core subject represented in this visual?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14339.jpg
What is being portrayed in this visual content?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14342.jpg
What is the principal component of this image?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041950_F3_14341.jpg
What is the core subject represented in this visual?
Characterization of the sco1-1 mutant. A-J are from 5-d-old light-grown seedlings, while K and L are from 4-d-old dark-grown seedlings. Upon seedling germination in white-light, the cotyledons of sco1-1 (B) appear colorless compared to wild type (A), but leaves that emerge from the apical meristem are green like wild-t...
PMC2041992_pgen-0030177-g004_14346.jpg
What is the main focus of this visual representation?
Degradation Pathways of Ataxin-3-Induced Neurodegeneration(A–E) External eyes of 1-d flies showing suppression of SCAtrQ78 toxicity by modifiers only (upper panel), and suppression by modifiers in limited proteasome background (lower panel) by expression of a dominant negative form of a 20S proteasome subunit [35].(A) ...
PMC2041992_pgen-0030177-g004_14348.jpg
What is the principal component of this image?
Degradation Pathways of Ataxin-3-Induced Neurodegeneration(A–E) External eyes of 1-d flies showing suppression of SCAtrQ78 toxicity by modifiers only (upper panel), and suppression by modifiers in limited proteasome background (lower panel) by expression of a dominant negative form of a 20S proteasome subunit [35].(A) ...
PMC2041992_pgen-0030177-g004_14344.jpg
What is the principal component of this image?
Degradation Pathways of Ataxin-3-Induced Neurodegeneration(A–E) External eyes of 1-d flies showing suppression of SCAtrQ78 toxicity by modifiers only (upper panel), and suppression by modifiers in limited proteasome background (lower panel) by expression of a dominant negative form of a 20S proteasome subunit [35].(A) ...
PMC2041992_pgen-0030177-g004_14345.jpg
What is being portrayed in this visual content?
Degradation Pathways of Ataxin-3-Induced Neurodegeneration(A–E) External eyes of 1-d flies showing suppression of SCAtrQ78 toxicity by modifiers only (upper panel), and suppression by modifiers in limited proteasome background (lower panel) by expression of a dominant negative form of a 20S proteasome subunit [35].(A) ...
PMC2041997_pgen-0030182-g005_14354.jpg
Can you identify the primary element in this image?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2041997_pgen-0030182-g005_14351.jpg
What can you see in this picture?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2041997_pgen-0030182-g005_14356.jpg
What's the most prominent thing you notice in this picture?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2041997_pgen-0030182-g005_14357.jpg
What is the principal component of this image?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2041997_pgen-0030182-g005_14355.jpg
What is the main focus of this visual representation?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2041997_pgen-0030182-g005_14353.jpg
What's the most prominent thing you notice in this picture?
HIRA Is Not Required for Protamine Removal from the Decondensing Sperm Nucleus(A) Left panel: in a fixed ProtA-GFP transgenic testis, the GFP fluorescence is very strong in the most condensed spermatid nuclei (asterisk), whereas less condensed nuclei are much less bright (arrow). Middle panel: the same testis stained w...
PMC2042986_F1_14361.jpg
What key item or scene is captured in this photo?
2D and 3D measurements of mitral valve circumference and area prior to the procedure.
PMC2042986_F1_14358.jpg
What object or scene is depicted here?
2D and 3D measurements of mitral valve circumference and area prior to the procedure.
PMC2042986_F1_14362.jpg
What is the principal component of this image?
2D and 3D measurements of mitral valve circumference and area prior to the procedure.
PMC2042986_F1_14360.jpg
What can you see in this picture?
2D and 3D measurements of mitral valve circumference and area prior to the procedure.
PMC2042986_F2_14365.jpg
What is the dominant medical problem in this image?
Preoperative 3D measurements of mitral annular volume (Measured from annulus to cusp).
PMC2042986_F2_14366.jpg
What stands out most in this visual?
Preoperative 3D measurements of mitral annular volume (Measured from annulus to cusp).
PMC2042986_F4_14368.jpg
What is the core subject represented in this visual?
2D and 3D measurements of mitral valve circumference and area after chordal cutting and ring placement.
PMC2042986_F4_14369.jpg
What object or scene is depicted here?
2D and 3D measurements of mitral valve circumference and area after chordal cutting and ring placement.
PMC2042986_F4_14367.jpg
Can you identify the primary element in this image?
2D and 3D measurements of mitral valve circumference and area after chordal cutting and ring placement.
PMC2042986_F5_14371.jpg
What is shown in this image?
3D measurement of annular volume of mitral valve (measured from annulus to cusp) after chordal cutting and ring placement.
PMC2042986_F5_14372.jpg
What is the core subject represented in this visual?
3D measurement of annular volume of mitral valve (measured from annulus to cusp) after chordal cutting and ring placement.
PMC2042986_F5_14373.jpg
What is the focal point of this photograph?
3D measurement of annular volume of mitral valve (measured from annulus to cusp) after chordal cutting and ring placement.
PMC2043489_pone-0001134-g005_14383.jpg
What is shown in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14377.jpg
What is the principal component of this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14378.jpg
What can you see in this picture?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14384.jpg
Can you identify the primary element in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14388.jpg
What is the focal point of this photograph?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14386.jpg
What is shown in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14387.jpg
Describe the main subject of this image.
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14375.jpg
What is the dominant medical problem in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14390.jpg
What is shown in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14379.jpg
Describe the main subject of this image.
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14393.jpg
What's the most prominent thing you notice in this picture?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14381.jpg
What is the focal point of this photograph?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14380.jpg
What does this image primarily show?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14389.jpg
Describe the main subject of this image.
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g005_14382.jpg
What is the dominant medical problem in this image?
DMPK is required for insulin receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with YFP-InsR along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l) or myc-ΔMADMPK (m–p). Shown are representative images of 3 independent experiments. Scale bar, 24 µm (applies t...
PMC2043489_pone-0001134-g007_14400.jpg
What is being portrayed in this visual content?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14398.jpg
Can you identify the primary element in this image?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14396.jpg
What can you see in this picture?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14409.jpg
What does this image primarily show?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14401.jpg
What object or scene is depicted here?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14408.jpg
What does this image primarily show?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14407.jpg
What stands out most in this visual?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14405.jpg
What can you see in this picture?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14403.jpg
Can you identify the primary element in this image?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043489_pone-0001134-g007_14399.jpg
What is the main focus of this visual representation?
DMPK is required for IGF-1 receptor targeting to the plasma membrane.(A) HeLa cells were transiently co-transfected with GFP-IGF-1 along with control empty vector (a–d), myc-WTDMPK (e–h), myc-K110ADMPK (i–l), or myc-ΔMADMPK- (m–p). Dotted arrows in panel k and l show a cell which only incorporated the GFP-IGF-1 plasmid...
PMC2043493_pone-0001116-g005_14412.jpg
What stands out most in this visual?
Fos expression reveals what dorsal horn neurons are activated during allodynia.(A) Images of Fos positive cell nuclei in the MDH; Fos was expressed following light brushing of the ipsilateral lip after intracisternal strychnine (top right). Contralateral side of the MDH in the same animal is shown on top left. Only spa...
PMC2043493_pone-0001116-g005_14417.jpg
What is the principal component of this image?
Fos expression reveals what dorsal horn neurons are activated during allodynia.(A) Images of Fos positive cell nuclei in the MDH; Fos was expressed following light brushing of the ipsilateral lip after intracisternal strychnine (top right). Contralateral side of the MDH in the same animal is shown on top left. Only spa...
PMC2043493_pone-0001116-g005_14416.jpg
What object or scene is depicted here?
Fos expression reveals what dorsal horn neurons are activated during allodynia.(A) Images of Fos positive cell nuclei in the MDH; Fos was expressed following light brushing of the ipsilateral lip after intracisternal strychnine (top right). Contralateral side of the MDH in the same animal is shown on top left. Only spa...
PMC2043493_pone-0001116-g005_14413.jpg
What can you see in this picture?
Fos expression reveals what dorsal horn neurons are activated during allodynia.(A) Images of Fos positive cell nuclei in the MDH; Fos was expressed following light brushing of the ipsilateral lip after intracisternal strychnine (top right). Contralateral side of the MDH in the same animal is shown on top left. Only spa...
PMC2043493_pone-0001116-g005_14415.jpg
What is shown in this image?
Fos expression reveals what dorsal horn neurons are activated during allodynia.(A) Images of Fos positive cell nuclei in the MDH; Fos was expressed following light brushing of the ipsilateral lip after intracisternal strychnine (top right). Contralateral side of the MDH in the same animal is shown on top left. Only spa...
PMC2043494_pone-0001142-g001_14423.jpg
What does this image primarily show?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14430.jpg
What is the dominant medical problem in this image?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14419.jpg
What is being portrayed in this visual content?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14436.jpg
What stands out most in this visual?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14435.jpg
What is the main focus of this visual representation?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14434.jpg
What is shown in this image?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14425.jpg
What is the core subject represented in this visual?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14429.jpg
What is the main focus of this visual representation?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14418.jpg
Can you identify the primary element in this image?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14422.jpg
Can you identify the primary element in this image?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14424.jpg
What can you see in this picture?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14427.jpg
What's the most prominent thing you notice in this picture?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14433.jpg
What is the principal component of this image?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14420.jpg
What is the core subject represented in this visual?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2043494_pone-0001142-g001_14428.jpg
What's the most prominent thing you notice in this picture?
Description of the Cranial Neural Crest Cells Delamination.(A–P) Transversal cryosections (10 µm) of normal chick embryos at stages 6s (A–D), 8s (E–H), 10s (I–L) and HH14 (M–P) at cranial (A–L) and trunk (M–P) levels. Sections were assayed for N-Cadherin expression by immunofluorescence (A, C, E, G, I, K, M, O). The ac...
PMC2045082_F1_14439.jpg
What is the core subject represented in this visual?
Illustrative case of TLISS use. Patient is an 18 y/o male who presents after a motor vehicle accident. Representative sagittal (A), coronal (B) and axial (C) computed tomography images were obtained. A compression fracture with angular deformity at T5 combined with a significant rotational injury is evident. Only the h...
PMC2045082_F1_14440.jpg
What key item or scene is captured in this photo?
Illustrative case of TLISS use. Patient is an 18 y/o male who presents after a motor vehicle accident. Representative sagittal (A), coronal (B) and axial (C) computed tomography images were obtained. A compression fracture with angular deformity at T5 combined with a significant rotational injury is evident. Only the h...
PMC2045082_F2_14443.jpg
What is the focal point of this photograph?
Second illustrative case of TLISS use. Patient is a 21 y/o male who presents after a motor vehicle accident. The patient was neurologically intact. Representative sagittal (A) and axial (B) computed tomography and sagittal T2-weighted magnetic resonance images (C) were obtained. A compression fracture with compromise o...
PMC2045082_F2_14442.jpg
What is the dominant medical problem in this image?
Second illustrative case of TLISS use. Patient is a 21 y/o male who presents after a motor vehicle accident. The patient was neurologically intact. Representative sagittal (A) and axial (B) computed tomography and sagittal T2-weighted magnetic resonance images (C) were obtained. A compression fracture with compromise o...
PMC2045086_F9_14445.jpg
What is shown in this image?
3D reconstruction CT scan showing oval shaped os odontoideum in relationship to the anterior normal arch of the atlas (arrow a); there is marked hypoplasia of the posterior arch of the atlas (arrow b).
PMC2045086_F9_14444.jpg
What is the dominant medical problem in this image?
3D reconstruction CT scan showing oval shaped os odontoideum in relationship to the anterior normal arch of the atlas (arrow a); there is marked hypoplasia of the posterior arch of the atlas (arrow b).
PMC2045087_F2_14446.jpg
What is the main focus of this visual representation?
Periapical radiograph for confirmation the presence of the impacted tooth. aA. Nasal cortical; B. Sinusal cortical (both corticals compose the Ennis inverted Y), the arrow points to dilaceration with possible apical ankylosis; C. Bone loss with fibrous scar, possibly due to two previous surgeries.
PMC2045087_F3_14447.jpg
What does this image primarily show?
Computed tomography (CT) of the maxilla in coronal (A) and axial (B) planes allows the visual analysis of the nasal, sinusal and vestibular intercortical relationships. Dilacerations or ankylosis on the root apical region of the impacted canine can be seen (A). In both images the absence of spongeous medullary bone aro...
PMC2045087_F3_14448.jpg
What object or scene is depicted here?
Computed tomography (CT) of the maxilla in coronal (A) and axial (B) planes allows the visual analysis of the nasal, sinusal and vestibular intercortical relationships. Dilacerations or ankylosis on the root apical region of the impacted canine can be seen (A). In both images the absence of spongeous medullary bone aro...
PMC2045087_F6_14450.jpg
What is the focal point of this photograph?
Periapical radiograph after the complete exposure of the tooth crow in the oral cavity and position in the dental arch. A. The apical fragment remains close to its preoperative position; B. The pulp root canal is almost completely obliterated.
PMC2045087_F6_14449.jpg
What does this image primarily show?
Periapical radiograph after the complete exposure of the tooth crow in the oral cavity and position in the dental arch. A. The apical fragment remains close to its preoperative position; B. The pulp root canal is almost completely obliterated.
PMC2045091_F1_14453.jpg
What is shown in this image?
T2-weighted magnetic resonance images showing coronal slices through 5-week-old rat brain at the level of the anterior third ventricle. Cerebrospinal fluid (CSF) is bright. In normal rats (and induction failures) the ventricles are barely visible (upper panel; arrow). Kaolin injected at age 3 weeks is associated with m...
PMC2045091_F1_14452.jpg
What object or scene is depicted here?
T2-weighted magnetic resonance images showing coronal slices through 5-week-old rat brain at the level of the anterior third ventricle. Cerebrospinal fluid (CSF) is bright. In normal rats (and induction failures) the ventricles are barely visible (upper panel; arrow). Kaolin injected at age 3 weeks is associated with m...
PMC2045091_F1_14451.jpg
What is the focal point of this photograph?
T2-weighted magnetic resonance images showing coronal slices through 5-week-old rat brain at the level of the anterior third ventricle. Cerebrospinal fluid (CSF) is bright. In normal rats (and induction failures) the ventricles are barely visible (upper panel; arrow). Kaolin injected at age 3 weeks is associated with m...
PMC2045104_F2_14454.jpg
What is the dominant medical problem in this image?
Histological examination of a skin biopsy specimen of the plaque showed on figure 1: lymphohistiocytic hypodermal infiltrate, associated with non-caseating multinucleated giant cells granulomas (Hematoxylin-eosin Strain; original magnification ×100).