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PMC2063502_F5_14594.jpg
Can you identify the primary element in this image?
Immunohistochemical localization of 14-3-3β (A and B) and mimecan (C and D) in myometrium (A and C) and leiomyomas (B and D) associated with leiomyoma and myometrial smooth muscle cells and cellular components of connective tissue and vasculature with inserts showing a higher magnification portion of these tissues. Inc...
PMC2063502_F5_14591.jpg
What is the dominant medical problem in this image?
Immunohistochemical localization of 14-3-3β (A and B) and mimecan (C and D) in myometrium (A and C) and leiomyomas (B and D) associated with leiomyoma and myometrial smooth muscle cells and cellular components of connective tissue and vasculature with inserts showing a higher magnification portion of these tissues. Inc...
PMC2063502_F5_14590.jpg
What is the principal component of this image?
Immunohistochemical localization of 14-3-3β (A and B) and mimecan (C and D) in myometrium (A and C) and leiomyomas (B and D) associated with leiomyoma and myometrial smooth muscle cells and cellular components of connective tissue and vasculature with inserts showing a higher magnification portion of these tissues. Inc...
PMC2063502_F5_14593.jpg
What is the focal point of this photograph?
Immunohistochemical localization of 14-3-3β (A and B) and mimecan (C and D) in myometrium (A and C) and leiomyomas (B and D) associated with leiomyoma and myometrial smooth muscle cells and cellular components of connective tissue and vasculature with inserts showing a higher magnification portion of these tissues. Inc...
PMC2063580_pone-0001132-g003_14602.jpg
What is the principal component of this image?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14604.jpg
What is the central feature of this picture?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14601.jpg
What is the focal point of this photograph?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14608.jpg
What is the core subject represented in this visual?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14605.jpg
Can you identify the primary element in this image?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14607.jpg
What is the dominant medical problem in this image?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14600.jpg
What is the focal point of this photograph?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14598.jpg
What is the main focus of this visual representation?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14610.jpg
What is being portrayed in this visual content?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063580_pone-0001132-g003_14611.jpg
What is being portrayed in this visual content?
The enrichment of Cbl at the lamellipodium was not dependent on Syk-Tyr323.Confocal microscopy images of dHL-60 cells (A) expressing EGFP-Syk or EGFP-Syk Y323F or (B) stably expressing a Syk-siRNA (siSyk). Upon stimulation by 100 nM fMLP on immobilized fibrinogen, Cbl was enriched at the lamellipodium of (A) EGFP-Syk t...
PMC2063610_fig05_14620.jpg
What stands out most in this visual?
In vitro co-culture with hESCs enhanced myogenesis of mouse cells. (A) 1 × 105 hESCs or control hMSCs were co-cultured with 5 × 106 primary mouse myoblasts. hESCs expressing Oct4 (immunodetection shown in red) dramatically enhanced myotube formation of co-cultured mouse myoblasts (immunodetection of eMyHC is shown in g...
PMC2063610_fig05_14627.jpg
What does this image primarily show?
In vitro co-culture with hESCs enhanced myogenesis of mouse cells. (A) 1 × 105 hESCs or control hMSCs were co-cultured with 5 × 106 primary mouse myoblasts. hESCs expressing Oct4 (immunodetection shown in red) dramatically enhanced myotube formation of co-cultured mouse myoblasts (immunodetection of eMyHC is shown in g...
PMC2063610_fig05_14622.jpg
What is the main focus of this visual representation?
In vitro co-culture with hESCs enhanced myogenesis of mouse cells. (A) 1 × 105 hESCs or control hMSCs were co-cultured with 5 × 106 primary mouse myoblasts. hESCs expressing Oct4 (immunodetection shown in red) dramatically enhanced myotube formation of co-cultured mouse myoblasts (immunodetection of eMyHC is shown in g...
PMC2063610_fig05_14621.jpg
What can you see in this picture?
In vitro co-culture with hESCs enhanced myogenesis of mouse cells. (A) 1 × 105 hESCs or control hMSCs were co-cultured with 5 × 106 primary mouse myoblasts. hESCs expressing Oct4 (immunodetection shown in red) dramatically enhanced myotube formation of co-cultured mouse myoblasts (immunodetection of eMyHC is shown in g...
PMC2063610_fig05_14626.jpg
What is the core subject represented in this visual?
In vitro co-culture with hESCs enhanced myogenesis of mouse cells. (A) 1 × 105 hESCs or control hMSCs were co-cultured with 5 × 106 primary mouse myoblasts. hESCs expressing Oct4 (immunodetection shown in red) dramatically enhanced myotube formation of co-cultured mouse myoblasts (immunodetection of eMyHC is shown in g...
PMC2063611_fig01_14615.jpg
What is the principal component of this image?
Rab27 proteins in BMMCsA) Bone marrow-derived mast cells derived from C57BL/6J wild-type, Rab27a KO (Rab27aash/ash), Rab27b KO (Rab27b−/−) and double KO (Rab27aash/ashRab27b−/−) mice were subjected to immunoblot analysis as described under Materials and Methods. B) Bone marrow-derived mast cells derived from C57BL/6J w...
PMC2063611_fig01_14614.jpg
What is the central feature of this picture?
Rab27 proteins in BMMCsA) Bone marrow-derived mast cells derived from C57BL/6J wild-type, Rab27a KO (Rab27aash/ash), Rab27b KO (Rab27b−/−) and double KO (Rab27aash/ashRab27b−/−) mice were subjected to immunoblot analysis as described under Materials and Methods. B) Bone marrow-derived mast cells derived from C57BL/6J w...
PMC2063611_fig01_14618.jpg
Can you identify the primary element in this image?
Rab27 proteins in BMMCsA) Bone marrow-derived mast cells derived from C57BL/6J wild-type, Rab27a KO (Rab27aash/ash), Rab27b KO (Rab27b−/−) and double KO (Rab27aash/ashRab27b−/−) mice were subjected to immunoblot analysis as described under Materials and Methods. B) Bone marrow-derived mast cells derived from C57BL/6J w...
PMC2063611_fig04_14637.jpg
What object or scene is depicted here?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14631.jpg
What key item or scene is captured in this photo?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14633.jpg
What key item or scene is captured in this photo?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14635.jpg
What's the most prominent thing you notice in this picture?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14632.jpg
What does this image primarily show?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14629.jpg
What object or scene is depicted here?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14636.jpg
What object or scene is depicted here?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14639.jpg
What is shown in this image?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14638.jpg
What key item or scene is captured in this photo?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14628.jpg
What is the principal component of this image?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2063611_fig04_14630.jpg
What is the principal component of this image?
Immunofluorescence analysis of mast cell secretory granules in BMMCs derived from Rab27-deficient miceBone marrow-derived mast cells derived from Rab27aash/+Rab27b−/+ (Double het), Rab27aash/ash (Rab27a KO), Rab27b−/− (Rab27b KO) and Rab27aash/ashRab27b−/− (Double KO) were subjected to immunofluorescence as described u...
PMC2064905_F1_14640.jpg
What is shown in this image?
Panoramic radiograph demonstrated a well-defined radiolucent lesion with sclerotic border in left mandibular canine region (white arrowhead). Small, radio-opaque masses with comparable radio densities to that of the surrounding teeth were seen inside the radiolucent lesion.
PMC2064905_F5_14641.jpg
What's the most prominent thing you notice in this picture?
Irregular melanosomes with some inclusions could be observed with higher magnification under transmission electron microscope (24,000×).
PMC2064906_F5_14648.jpg
What object or scene is depicted here?
Immunofluorescence and confocal microscopical analysis of p47phox localization in LPS-stimulated microlgia cells. HAPI cells were treated with LPS for 10 min in the absence or presence of SN pretreatment for 0.5 h. Cells were immunostained with a rabbit polyclonal antibody against p47phox, then washed and incubated wit...
PMC2064906_F5_14645.jpg
What is the dominant medical problem in this image?
Immunofluorescence and confocal microscopical analysis of p47phox localization in LPS-stimulated microlgia cells. HAPI cells were treated with LPS for 10 min in the absence or presence of SN pretreatment for 0.5 h. Cells were immunostained with a rabbit polyclonal antibody against p47phox, then washed and incubated wit...
PMC2064906_F5_14646.jpg
What is the core subject represented in this visual?
Immunofluorescence and confocal microscopical analysis of p47phox localization in LPS-stimulated microlgia cells. HAPI cells were treated with LPS for 10 min in the absence or presence of SN pretreatment for 0.5 h. Cells were immunostained with a rabbit polyclonal antibody against p47phox, then washed and incubated wit...
PMC2064906_F5_14644.jpg
What stands out most in this visual?
Immunofluorescence and confocal microscopical analysis of p47phox localization in LPS-stimulated microlgia cells. HAPI cells were treated with LPS for 10 min in the absence or presence of SN pretreatment for 0.5 h. Cells were immunostained with a rabbit polyclonal antibody against p47phox, then washed and incubated wit...
PMC2064906_F5_14643.jpg
What is the focal point of this photograph?
Immunofluorescence and confocal microscopical analysis of p47phox localization in LPS-stimulated microlgia cells. HAPI cells were treated with LPS for 10 min in the absence or presence of SN pretreatment for 0.5 h. Cells were immunostained with a rabbit polyclonal antibody against p47phox, then washed and incubated wit...
PMC2064911_F2_14650.jpg
What can you see in this picture?
Measurement of left ventricular end-diastolic diameter (EDD) and end-systolic diameter (ESD) from M-mode (down), guided by a parasternal short axis image (upper) to optimize medial-lateral beam orientation.
PMC2064911_F2_14651.jpg
What is the main focus of this visual representation?
Measurement of left ventricular end-diastolic diameter (EDD) and end-systolic diameter (ESD) from M-mode (down), guided by a parasternal short axis image (upper) to optimize medial-lateral beam orientation.
PMC2064913_F2_14659.jpg
What is the main focus of this visual representation?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14658.jpg
What is the principal component of this image?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14653.jpg
What can you see in this picture?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14656.jpg
What can you see in this picture?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14652.jpg
What object or scene is depicted here?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14660.jpg
What is shown in this image?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F2_14655.jpg
What is being portrayed in this visual content?
Confocal microscopy to observe both GFP and huCD36 protein expression. Constructs of pEGFP-C3-CD36, pEGFP-N3-CD36, and pEGFP-N3 vector alone, were transit-transfected into CHO cells for 48 hours, and the transfected cells were then immunostained with anti-CD36 antibody, counter-stained with TRIC-conjugated anti-mouse I...
PMC2064913_F4_14671.jpg
Describe the main subject of this image.
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14661.jpg
What object or scene is depicted here?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14662.jpg
What is the core subject represented in this visual?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14665.jpg
What is the main focus of this visual representation?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14667.jpg
What key item or scene is captured in this photo?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14669.jpg
What is the core subject represented in this visual?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14670.jpg
Describe the main subject of this image.
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14664.jpg
Can you identify the primary element in this image?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14666.jpg
What is the central feature of this picture?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14668.jpg
What is the core subject represented in this visual?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064913_F4_14663.jpg
What is the dominant medical problem in this image?
pEGFP-C3-CD36 limited OxLDL uptake, but not for pEGFP-N3-CD36. pEGFP-C3-CD36 and pEGFP-N3-CD36, as well as pEGFP-N3 alone were transit-transfected into CHO cells. After transfection for 48 hours, cells were rinsed twice with PBS and Dil-oxLDL at 10 μg/ml was incubated with the transfected cells for 1 hour. After rinsed...
PMC2064914_F9_14672.jpg
What's the most prominent thing you notice in this picture?
Micrographs of hematoxylin/periodic acid Schiff stained colonic biopsies. (A) biopsy from control patient – not mounted. (B) biopsy from control patient – mounted for 2 hrs in the MUAS chamber. The histology is the same and in particular the epithelial surface is intact. Similar results exist for biopsies from D-patien...
PMC2064914_F9_14673.jpg
What is the main focus of this visual representation?
Micrographs of hematoxylin/periodic acid Schiff stained colonic biopsies. (A) biopsy from control patient – not mounted. (B) biopsy from control patient – mounted for 2 hrs in the MUAS chamber. The histology is the same and in particular the epithelial surface is intact. Similar results exist for biopsies from D-patien...
PMC2064921_F1_14674.jpg
What does this image primarily show?
The 3D view of gradient vector field and diffused gradient vector field with elastic deformation transformation of a slice cropped from a 3D cell nuclei image. (a). A slice of the 3D image. (b). The original gradient vector field. (c). The diffused gradient flow field with elastic deformation transformation. Obviously,...
PMC2064921_F1_14678.jpg
What is the dominant medical problem in this image?
The 3D view of gradient vector field and diffused gradient vector field with elastic deformation transformation of a slice cropped from a 3D cell nuclei image. (a). A slice of the 3D image. (b). The original gradient vector field. (c). The diffused gradient flow field with elastic deformation transformation. Obviously,...
PMC2064921_F1_14675.jpg
What does this image primarily show?
The 3D view of gradient vector field and diffused gradient vector field with elastic deformation transformation of a slice cropped from a 3D cell nuclei image. (a). A slice of the 3D image. (b). The original gradient vector field. (c). The diffused gradient flow field with elastic deformation transformation. Obviously,...
PMC2064932_F5_14682.jpg
What is the focal point of this photograph?
Morphological analysis of in vitro assembled mutant CAp24 proteins. Mutant and wild type CAp24 proteins were induced for in vitro CAp24 tubular formation (see Fig. 3). At the end of the experiment, the proteins were fixed in freshly prepared 2.5% glutaraldehyde. The electron micrographs show negatively stained thin-sec...
PMC2064932_F5_14680.jpg
What is the main focus of this visual representation?
Morphological analysis of in vitro assembled mutant CAp24 proteins. Mutant and wild type CAp24 proteins were induced for in vitro CAp24 tubular formation (see Fig. 3). At the end of the experiment, the proteins were fixed in freshly prepared 2.5% glutaraldehyde. The electron micrographs show negatively stained thin-sec...
PMC2064932_F5_14679.jpg
What does this image primarily show?
Morphological analysis of in vitro assembled mutant CAp24 proteins. Mutant and wild type CAp24 proteins were induced for in vitro CAp24 tubular formation (see Fig. 3). At the end of the experiment, the proteins were fixed in freshly prepared 2.5% glutaraldehyde. The electron micrographs show negatively stained thin-sec...
PMC2064932_F5_14681.jpg
What is the main focus of this visual representation?
Morphological analysis of in vitro assembled mutant CAp24 proteins. Mutant and wild type CAp24 proteins were induced for in vitro CAp24 tubular formation (see Fig. 3). At the end of the experiment, the proteins were fixed in freshly prepared 2.5% glutaraldehyde. The electron micrographs show negatively stained thin-sec...
PMC2064932_F9_14684.jpg
What is shown in this image?
TEM analysis of mutant virus particles. Electron micrographs of mutant and wild type virus particles. Mutants D51N and D51Q showed mostly heterogenous populations of particles with varying size and morphology (panels D51Q and inset in panel D51N). No virus particles with conical core structures were observed with these...
PMC2064932_F9_14688.jpg
What does this image primarily show?
TEM analysis of mutant virus particles. Electron micrographs of mutant and wild type virus particles. Mutants D51N and D51Q showed mostly heterogenous populations of particles with varying size and morphology (panels D51Q and inset in panel D51N). No virus particles with conical core structures were observed with these...
PMC2064932_F9_14686.jpg
What stands out most in this visual?
TEM analysis of mutant virus particles. Electron micrographs of mutant and wild type virus particles. Mutants D51N and D51Q showed mostly heterogenous populations of particles with varying size and morphology (panels D51Q and inset in panel D51N). No virus particles with conical core structures were observed with these...
PMC2064932_F9_14687.jpg
What is the central feature of this picture?
TEM analysis of mutant virus particles. Electron micrographs of mutant and wild type virus particles. Mutants D51N and D51Q showed mostly heterogenous populations of particles with varying size and morphology (panels D51Q and inset in panel D51N). No virus particles with conical core structures were observed with these...
PMC2064946_Fig1_14692.jpg
What object or scene is depicted here?
Cellular mechanism of sodium reabsorption in principal cells of collecting ducts from normal rats and nephrotic rats. Sodium reabsorption in principal cells proceeds along a two-step mechanism that includes active extrusion of intracellular sodium ions by the basolateral Na,K-ATPase and passive apical entry of sodium v...
PMC2064946_Fig1_14690.jpg
What is the focal point of this photograph?
Cellular mechanism of sodium reabsorption in principal cells of collecting ducts from normal rats and nephrotic rats. Sodium reabsorption in principal cells proceeds along a two-step mechanism that includes active extrusion of intracellular sodium ions by the basolateral Na,K-ATPase and passive apical entry of sodium v...
PMC2064946_Fig1_14691.jpg
What is shown in this image?
Cellular mechanism of sodium reabsorption in principal cells of collecting ducts from normal rats and nephrotic rats. Sodium reabsorption in principal cells proceeds along a two-step mechanism that includes active extrusion of intracellular sodium ions by the basolateral Na,K-ATPase and passive apical entry of sodium v...
PMC2064946_Fig1_14689.jpg
What can you see in this picture?
Cellular mechanism of sodium reabsorption in principal cells of collecting ducts from normal rats and nephrotic rats. Sodium reabsorption in principal cells proceeds along a two-step mechanism that includes active extrusion of intracellular sodium ions by the basolateral Na,K-ATPase and passive apical entry of sodium v...
PMC2064959_pone-0001168-g004_14695.jpg
What is the principal component of this image?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064959_pone-0001168-g004_14698.jpg
What's the most prominent thing you notice in this picture?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064959_pone-0001168-g004_14696.jpg
What is the main focus of this visual representation?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064959_pone-0001168-g004_14694.jpg
Can you identify the primary element in this image?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064959_pone-0001168-g004_14699.jpg
What is the principal component of this image?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064959_pone-0001168-g004_14697.jpg
What is shown in this image?
Immunocytochemical preparations of Aedes albopictus tissues infected with CHIKV 06.21.(A) midgut day 1 pi. (B) salivary glands day 2 pi. (C) ovaries day 6 pi. (D) nervous central system day 9 pi. (E) CHIKV-infected C6/36 cells as positive control. (F) non infected C6/36 cells as negative control. Magnification: ×100.
PMC2064963_pone-0001178-g003_14702.jpg
What is the main focus of this visual representation?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064963_pone-0001178-g003_14705.jpg
What object or scene is depicted here?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064963_pone-0001178-g003_14707.jpg
What is being portrayed in this visual content?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064963_pone-0001178-g003_14701.jpg
Can you identify the primary element in this image?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064963_pone-0001178-g003_14700.jpg
What is being portrayed in this visual content?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064963_pone-0001178-g003_14703.jpg
What is the focal point of this photograph?
Toll-8 is expressed at varying levels in the disc epithelium and expression is extinguished in the neural precursors.(A–B'), GFP expression driven by the Toll-8[MD806]Gal4 driver in discs from third instar larvae (A, A') and white prepupae (B, B') respectively. Expression is strong over the lateral notum but is exclu...
PMC2064965_pone-0001169-g001_14710.jpg
What is being portrayed in this visual content?
Differential rostro-caudal pattern of Delta-1 expression in the prospective chick spinal cord and its spatial correlation to neurogenesis.A. ISH of Delta-1 in a HH11 chick embryo showing expression in the caudal neural plate (CNP), the last formed caudal somites (NS), the prospective spinal cord (SC), and the presomiti...
PMC2064965_pone-0001169-g002_14716.jpg
What is the core subject represented in this visual?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14722.jpg
What is the core subject represented in this visual?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14714.jpg
What stands out most in this visual?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14720.jpg
What is the focal point of this photograph?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14721.jpg
What is being portrayed in this visual content?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14718.jpg
Describe the main subject of this image.
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14715.jpg
What key item or scene is captured in this photo?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14713.jpg
What is the main focus of this visual representation?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g002_14719.jpg
What's the most prominent thing you notice in this picture?
Delta-1 is expressed in cycling neural progenitor cells.Double immunolabelling of Delta-1 mRNA and cell cycle markers in transverse sections of the prospective spinal cord at the level of the last five caudal somites in HH10 chick embryos. Confocal optical sections of 6 µm are shown and double labelled cells are indic...
PMC2064965_pone-0001169-g005_14727.jpg
Can you identify the primary element in this image?
Spatio-temporal analysis of neuronal generation induced by Delta-1 expression.A–I Confocal projections (40–50 µm) from a dorsal point of view of the prospective spinal cord of embryos transfected with pCIG-Delta-1, pCIG-Delta-1/pCIG-DeltaDN, pCIG (controls), Delta-1 anti-sense (MO1-cDelta1 and MO2-cDelta1) and control ...