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PMC2129115_pone-0001334-g004_15308.jpg
Describe the main subject of this image.
CEBPD protein expression in mouse ovaries.(A) Immunohistochemistry for CEBPD in ovaries from wild-type (WT) or Cebpd null mutant (KO) mice at the indicated time points following hCG treatment. (B, C) Immunohistochemistry for CEBPD and alpha smooth muscle actin (ACTA2) in wild-type ovaries harvested 3 h after hCG treatm...
PMC2129115_pone-0001334-g004_15305.jpg
What can you see in this picture?
CEBPD protein expression in mouse ovaries.(A) Immunohistochemistry for CEBPD in ovaries from wild-type (WT) or Cebpd null mutant (KO) mice at the indicated time points following hCG treatment. (B, C) Immunohistochemistry for CEBPD and alpha smooth muscle actin (ACTA2) in wild-type ovaries harvested 3 h after hCG treatm...
PMC2129120_pone-0001327-g009_15315.jpg
What's the most prominent thing you notice in this picture?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15314.jpg
What key item or scene is captured in this photo?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15321.jpg
What stands out most in this visual?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15317.jpg
What object or scene is depicted here?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15316.jpg
What is the main focus of this visual representation?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15318.jpg
What is the central feature of this picture?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15312.jpg
What is the central feature of this picture?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15320.jpg
What is being portrayed in this visual content?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129120_pone-0001327-g009_15311.jpg
What's the most prominent thing you notice in this picture?
HCN2 concentrate at the tips of RBC dendrites, at sites of synaptic input from rods.A, Close–up view of the HCN1/PKC double staining. Further magnification of the field within the box is shown below. HCN1 express diffusely within the OPL, but do not colocalize with RBCs. B, Analogous close–up of an HCN2/PKC section sho...
PMC2129121_pone-0001338-g003_15324.jpg
Can you identify the primary element in this image?
Lin- cKit+Flk-1+ BM cells have endothelial properties.A) Schematic representation of the experimental procedure. B) Immunofluorescence on matrigel sections showing the incorporation of GFP+ Lin- c-kit+ Flk-1+ cells into vessels (arrowheads). Yellow and orange insets show magnification of GFP+ cells. Green: GFP; Red: VE...
PMC2129121_pone-0001338-g003_15323.jpg
What is the principal component of this image?
Lin- cKit+Flk-1+ BM cells have endothelial properties.A) Schematic representation of the experimental procedure. B) Immunofluorescence on matrigel sections showing the incorporation of GFP+ Lin- c-kit+ Flk-1+ cells into vessels (arrowheads). Yellow and orange insets show magnification of GFP+ cells. Green: GFP; Red: VE...
PMC2131757_F2_15329.jpg
What is the main focus of this visual representation?
MoPrP105-132 avoids early endosomes and lysosomes. Neuroblastoma incubated with biotinylated MoPrP105-132 at 37°C, then fixed and stained with Texas Red-streptavidin (red) and TfR-FITC (green) or LAMP-1-FITC (green). Nuclei were revealed using Vectashield with DAPI (blue). (A) Co-localisation (yellow) was not observed ...
PMC2131757_F2_15330.jpg
What's the most prominent thing you notice in this picture?
MoPrP105-132 avoids early endosomes and lysosomes. Neuroblastoma incubated with biotinylated MoPrP105-132 at 37°C, then fixed and stained with Texas Red-streptavidin (red) and TfR-FITC (green) or LAMP-1-FITC (green). Nuclei were revealed using Vectashield with DAPI (blue). (A) Co-localisation (yellow) was not observed ...
PMC2131757_F2_15328.jpg
What is the dominant medical problem in this image?
MoPrP105-132 avoids early endosomes and lysosomes. Neuroblastoma incubated with biotinylated MoPrP105-132 at 37°C, then fixed and stained with Texas Red-streptavidin (red) and TfR-FITC (green) or LAMP-1-FITC (green). Nuclei were revealed using Vectashield with DAPI (blue). (A) Co-localisation (yellow) was not observed ...
PMC2131778_pone-0001352-g004_15333.jpg
What does this image primarily show?
(A) Movement of carmine particles near the division plane in algae-free P. bursaria at dividing phase.An algae-free P. bursaria having carmine particles (arrowheads) was monitored using video-microscopy (Left and Middle panel: 0 min and 5 min after initiating the observation, respectively). The right panel is a schemat...
PMC2131778_pone-0001352-g004_15334.jpg
What key item or scene is captured in this photo?
(A) Movement of carmine particles near the division plane in algae-free P. bursaria at dividing phase.An algae-free P. bursaria having carmine particles (arrowheads) was monitored using video-microscopy (Left and Middle panel: 0 min and 5 min after initiating the observation, respectively). The right panel is a schemat...
PMC2131778_pone-0001352-g004_15335.jpg
What is the focal point of this photograph?
(A) Movement of carmine particles near the division plane in algae-free P. bursaria at dividing phase.An algae-free P. bursaria having carmine particles (arrowheads) was monitored using video-microscopy (Left and Middle panel: 0 min and 5 min after initiating the observation, respectively). The right panel is a schemat...
PMC2131779_pone-0001353-g004_15340.jpg
What is the central feature of this picture?
Hyperproliferation in CEABAC mouse colonic epithelium at 3 weeks of age.A) Extension of the proliferative zones in colonic crypts is shown for both CEABAC10 and CEABAC20 by PCNA staining. Lengthening of crypts, poor cryptal alignment, increase of peri-cryptal stroma, and elongation of nuclei are noted in CEABAC20 mice,...
PMC2131779_pone-0001353-g004_15341.jpg
What does this image primarily show?
Hyperproliferation in CEABAC mouse colonic epithelium at 3 weeks of age.A) Extension of the proliferative zones in colonic crypts is shown for both CEABAC10 and CEABAC20 by PCNA staining. Lengthening of crypts, poor cryptal alignment, increase of peri-cryptal stroma, and elongation of nuclei are noted in CEABAC20 mice,...
PMC2131779_pone-0001353-g004_15342.jpg
What is the focal point of this photograph?
Hyperproliferation in CEABAC mouse colonic epithelium at 3 weeks of age.A) Extension of the proliferative zones in colonic crypts is shown for both CEABAC10 and CEABAC20 by PCNA staining. Lengthening of crypts, poor cryptal alignment, increase of peri-cryptal stroma, and elongation of nuclei are noted in CEABAC20 mice,...
PMC2131779_pone-0001353-g004_15344.jpg
What's the most prominent thing you notice in this picture?
Hyperproliferation in CEABAC mouse colonic epithelium at 3 weeks of age.A) Extension of the proliferative zones in colonic crypts is shown for both CEABAC10 and CEABAC20 by PCNA staining. Lengthening of crypts, poor cryptal alignment, increase of peri-cryptal stroma, and elongation of nuclei are noted in CEABAC20 mice,...
PMC2131779_pone-0001353-g004_15338.jpg
Describe the main subject of this image.
Hyperproliferation in CEABAC mouse colonic epithelium at 3 weeks of age.A) Extension of the proliferative zones in colonic crypts is shown for both CEABAC10 and CEABAC20 by PCNA staining. Lengthening of crypts, poor cryptal alignment, increase of peri-cryptal stroma, and elongation of nuclei are noted in CEABAC20 mice,...
PMC2131779_pone-0001353-g005_15346.jpg
What is shown in this image?
Differentiation block in CEABAC mouse colonic epithelium at 3 weeks of age.A) Mucin staining of colonic crypts of WT, CEABAC2, CEABAC10, and CEABAC20 mice shows a progressively decreasing number of visible purplish-colored differentiated goblet cells (indicated by an arrow in the WT colonic crypt) correlated with incre...
PMC2131779_pone-0001353-g005_15345.jpg
Can you identify the primary element in this image?
Differentiation block in CEABAC mouse colonic epithelium at 3 weeks of age.A) Mucin staining of colonic crypts of WT, CEABAC2, CEABAC10, and CEABAC20 mice shows a progressively decreasing number of visible purplish-colored differentiated goblet cells (indicated by an arrow in the WT colonic crypt) correlated with incre...
PMC2131779_pone-0001353-g005_15348.jpg
What object or scene is depicted here?
Differentiation block in CEABAC mouse colonic epithelium at 3 weeks of age.A) Mucin staining of colonic crypts of WT, CEABAC2, CEABAC10, and CEABAC20 mice shows a progressively decreasing number of visible purplish-colored differentiated goblet cells (indicated by an arrow in the WT colonic crypt) correlated with incre...
PMC2131779_pone-0001353-g005_15349.jpg
What is the principal component of this image?
Differentiation block in CEABAC mouse colonic epithelium at 3 weeks of age.A) Mucin staining of colonic crypts of WT, CEABAC2, CEABAC10, and CEABAC20 mice shows a progressively decreasing number of visible purplish-colored differentiated goblet cells (indicated by an arrow in the WT colonic crypt) correlated with incre...
PMC2131782_pone-0001355-g003_15350.jpg
What key item or scene is captured in this photo?
Induction of Cre-mediated recombination in DiCre×Z/EG mice.A: The presence of recombination is shown by EGFP expression in the heart of DiCre×Z/EG adult animals ten days after the end of treatment with the inducer (5×10 mg/kg rapamycin i.p.). B: In the absence of rapamycin treatment no specific fluorescence can be seen...
PMC2131782_pone-0001355-g003_15351.jpg
What can you see in this picture?
Induction of Cre-mediated recombination in DiCre×Z/EG mice.A: The presence of recombination is shown by EGFP expression in the heart of DiCre×Z/EG adult animals ten days after the end of treatment with the inducer (5×10 mg/kg rapamycin i.p.). B: In the absence of rapamycin treatment no specific fluorescence can be seen...
PMC2134953_ppat-0030186-g003_15363.jpg
What is the main focus of this visual representation?
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2134953_ppat-0030186-g003_15361.jpg
What's the most prominent thing you notice in this picture?
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2134953_ppat-0030186-g003_15355.jpg
Describe the main subject of this image.
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2134953_ppat-0030186-g003_15362.jpg
What is the core subject represented in this visual?
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2134953_ppat-0030186-g003_15359.jpg
What is the principal component of this image?
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2134953_ppat-0030186-g003_15357.jpg
What is the dominant medical problem in this image?
EBP50 Controls iNOS Localization Relative to Phagosomes(A and B) Macrophages were transfected with EBP50-GFP, stimulated with IFN-γ and LPS for 16 h, and then allowed to phagocytose Texas Red–labeled latex beads for 10 min. After 1-h chase, cells were fixed, stained for iNOS, and examined by confocal microscopy.(A) Con...
PMC2137107_f1-ehp0115-a0580a_15364.jpg
What key item or scene is captured in this photo?
Taking a cue from kittyHealth effects seen in cats exposed to PBDEs may offer insights into how these chemicals affect humans.
PMC2137931_pone-0001362-g002_15371.jpg
What can you see in this picture?
Imaging of NVM in patient III:8 of family DU-11.A, Magnetic resonance image: long-axis plane in diastole. Prominent myocardial trabeculations and deep intertrabecular recesses are seen in the apical half of the right and left ventricle as indicated by arrows. B, Magnetic resonance image: short-axis plane in diastole. I...
PMC2137931_pone-0001362-g002_15369.jpg
What's the most prominent thing you notice in this picture?
Imaging of NVM in patient III:8 of family DU-11.A, Magnetic resonance image: long-axis plane in diastole. Prominent myocardial trabeculations and deep intertrabecular recesses are seen in the apical half of the right and left ventricle as indicated by arrows. B, Magnetic resonance image: short-axis plane in diastole. I...
PMC2137931_pone-0001362-g003_15367.jpg
What is being portrayed in this visual content?
Imaging of NVM in the index patient (III:4, panel A) and her sister's daughter (IV:13, panel B).Shown are two-dimensional echocardiographs (ventricular part of a four-chamber view) in diastole, with (right) and without (left) color flow imaging. Arrows point to recesses in the myocardial wall.
PMC2137931_pone-0001362-g003_15366.jpg
What does this image primarily show?
Imaging of NVM in the index patient (III:4, panel A) and her sister's daughter (IV:13, panel B).Shown are two-dimensional echocardiographs (ventricular part of a four-chamber view) in diastole, with (right) and without (left) color flow imaging. Arrows point to recesses in the myocardial wall.
PMC2140052_F2_15372.jpg
What's the most prominent thing you notice in this picture?
Bone marrow trephine biopsy shows spindle shaped malignant cells with dark brown granules of melanin pigment lying in the background of extensive fibrosis, H&E × 600.
PMC2140062_F5_15376.jpg
Describe the main subject of this image.
In situ hybridizations for per1 (upper) and per2 (middle panels) expression in four sagittal brain sections from sleep deprived (SD, right) and control (left panels) mice. All sections were taken close to mid-line (see lower panel; red vertical line in coronal section indicates the plane of the sagittal sections). per ...
PMC2140062_F5_15373.jpg
What is the principal component of this image?
In situ hybridizations for per1 (upper) and per2 (middle panels) expression in four sagittal brain sections from sleep deprived (SD, right) and control (left panels) mice. All sections were taken close to mid-line (see lower panel; red vertical line in coronal section indicates the plane of the sagittal sections). per ...
PMC2140062_F5_15374.jpg
What's the most prominent thing you notice in this picture?
In situ hybridizations for per1 (upper) and per2 (middle panels) expression in four sagittal brain sections from sleep deprived (SD, right) and control (left panels) mice. All sections were taken close to mid-line (see lower panel; red vertical line in coronal section indicates the plane of the sagittal sections). per ...
PMC2140062_F5_15375.jpg
What can you see in this picture?
In situ hybridizations for per1 (upper) and per2 (middle panels) expression in four sagittal brain sections from sleep deprived (SD, right) and control (left panels) mice. All sections were taken close to mid-line (see lower panel; red vertical line in coronal section indicates the plane of the sagittal sections). per ...
PMC2140062_F5_15377.jpg
What key item or scene is captured in this photo?
In situ hybridizations for per1 (upper) and per2 (middle panels) expression in four sagittal brain sections from sleep deprived (SD, right) and control (left panels) mice. All sections were taken close to mid-line (see lower panel; red vertical line in coronal section indicates the plane of the sagittal sections). per ...
PMC2140087_pmed-0040329-g003_15384.jpg
What is the central feature of this picture?
Immunofluorescence Confirmation of IBCs and Filaments in Urines from Women with CystitisUrines from women with cystitis were stained with antibodies against E. coli (green) and uroplakin III (red). Confocal microscopy analysis revealed large collections of bacteria (A) and cells with partial membrane and cytoplasmic ur...
PMC2140087_pmed-0040329-g003_15380.jpg
What is shown in this image?
Immunofluorescence Confirmation of IBCs and Filaments in Urines from Women with CystitisUrines from women with cystitis were stained with antibodies against E. coli (green) and uroplakin III (red). Confocal microscopy analysis revealed large collections of bacteria (A) and cells with partial membrane and cytoplasmic ur...
PMC2140087_pmed-0040329-g003_15381.jpg
What's the most prominent thing you notice in this picture?
Immunofluorescence Confirmation of IBCs and Filaments in Urines from Women with CystitisUrines from women with cystitis were stained with antibodies against E. coli (green) and uroplakin III (red). Confocal microscopy analysis revealed large collections of bacteria (A) and cells with partial membrane and cytoplasmic ur...
PMC2140087_pmed-0040329-g003_15378.jpg
What object or scene is depicted here?
Immunofluorescence Confirmation of IBCs and Filaments in Urines from Women with CystitisUrines from women with cystitis were stained with antibodies against E. coli (green) and uroplakin III (red). Confocal microscopy analysis revealed large collections of bacteria (A) and cells with partial membrane and cytoplasmic ur...
PMC2140263_F4_15389.jpg
Can you identify the primary element in this image?
Normal-weight volunteer. Results of comparison for normal-weight (75 kg, 188 cm) volunteer, for 2D and 3D LD studies.
PMC2140263_F4_15385.jpg
What is the central feature of this picture?
Normal-weight volunteer. Results of comparison for normal-weight (75 kg, 188 cm) volunteer, for 2D and 3D LD studies.
PMC2140263_F4_15388.jpg
What is the dominant medical problem in this image?
Normal-weight volunteer. Results of comparison for normal-weight (75 kg, 188 cm) volunteer, for 2D and 3D LD studies.
PMC2140263_F4_15390.jpg
What's the most prominent thing you notice in this picture?
Normal-weight volunteer. Results of comparison for normal-weight (75 kg, 188 cm) volunteer, for 2D and 3D LD studies.
PMC2140263_F4_15387.jpg
What is the focal point of this photograph?
Normal-weight volunteer. Results of comparison for normal-weight (75 kg, 188 cm) volunteer, for 2D and 3D LD studies.
PMC2144768_pone-0001292-g004_15394.jpg
What does this image primarily show?
Significant clusters from the random effects contrast painful>non-painful (intensity and unpleasantness rating trials pooled) of fMRI experiment I, displayed on a high-resolution structural MRI template in MNI space (used in all figures, displayed in neurological convention; red numbers indicate slice number).The anato...
PMC2144768_pone-0001292-g004_15395.jpg
What is the main focus of this visual representation?
Significant clusters from the random effects contrast painful>non-painful (intensity and unpleasantness rating trials pooled) of fMRI experiment I, displayed on a high-resolution structural MRI template in MNI space (used in all figures, displayed in neurological convention; red numbers indicate slice number).The anato...
PMC2144768_pone-0001292-g004_15399.jpg
What is the principal component of this image?
Significant clusters from the random effects contrast painful>non-painful (intensity and unpleasantness rating trials pooled) of fMRI experiment I, displayed on a high-resolution structural MRI template in MNI space (used in all figures, displayed in neurological convention; red numbers indicate slice number).The anato...
PMC2144768_pone-0001292-g004_15400.jpg
What's the most prominent thing you notice in this picture?
Significant clusters from the random effects contrast painful>non-painful (intensity and unpleasantness rating trials pooled) of fMRI experiment I, displayed on a high-resolution structural MRI template in MNI space (used in all figures, displayed in neurological convention; red numbers indicate slice number).The anato...
PMC2144768_pone-0001292-g006_15401.jpg
Can you identify the primary element in this image?
Additional clusters in orbitofrontal cortex (OFC) and subcallosal/perigenual ACC when contrasting the biopsy with the injection condition during pain intensity ratings (numbed>injection; intensity rating trials only).Threshold P = 0.005 (uncorrected), k = 5.
PMC2144768_pone-0001292-g006_15404.jpg
What object or scene is depicted here?
Additional clusters in orbitofrontal cortex (OFC) and subcallosal/perigenual ACC when contrasting the biopsy with the injection condition during pain intensity ratings (numbed>injection; intensity rating trials only).Threshold P = 0.005 (uncorrected), k = 5.
PMC2144768_pone-0001292-g006_15402.jpg
Describe the main subject of this image.
Additional clusters in orbitofrontal cortex (OFC) and subcallosal/perigenual ACC when contrasting the biopsy with the injection condition during pain intensity ratings (numbed>injection; intensity rating trials only).Threshold P = 0.005 (uncorrected), k = 5.
PMC2146996_F1_15412.jpg
What is the central feature of this picture?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F1_15408.jpg
What key item or scene is captured in this photo?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F1_15407.jpg
What is the principal component of this image?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F1_15411.jpg
What is shown in this image?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F1_15409.jpg
What is the main focus of this visual representation?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F1_15410.jpg
What is being portrayed in this visual content?
Micrographs demonstrating AMG silver enhanced clustered gold nanoparticles in mouse after in vivo exposure. (a) 40 nm gold particles clustered in Kupffer cells of the liver from a pregnant mouse. (b) Section from a fetal liver taken from an embryo of the same animal. Note that the fetal tissue is completely void of sta...
PMC2146996_F2_15405.jpg
What is the focal point of this photograph?
Electron micrographs showing AMG enhanced clustered gold nanoparticles in the lysosomes of a Kupffer cell (a) and a spleen macrophage (b). The animal was exposed to 40 nm gold nanoparticles intravenously and allowed to survive for 24 hours. Scalebars = 2 μm.
PMC2146996_F2_15406.jpg
What key item or scene is captured in this photo?
Electron micrographs showing AMG enhanced clustered gold nanoparticles in the lysosomes of a Kupffer cell (a) and a spleen macrophage (b). The animal was exposed to 40 nm gold nanoparticles intravenously and allowed to survive for 24 hours. Scalebars = 2 μm.
PMC2146999_F1_15414.jpg
What is the focal point of this photograph?
Preoperative imaging with 99 m Tc sestamibi scan (left). Utilization of previous scar (arrow). Extent of incision used for VAM (vertical lines) and its relation to the sternal notch (SN) (right).
PMC2147031_F4_15430.jpg
What is shown in this image?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15424.jpg
What is the principal component of this image?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15426.jpg
What does this image primarily show?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15416.jpg
What's the most prominent thing you notice in this picture?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15417.jpg
What is being portrayed in this visual content?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15419.jpg
What key item or scene is captured in this photo?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15427.jpg
What object or scene is depicted here?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147031_F4_15425.jpg
What is the focal point of this photograph?
Using electroporation to study retino-tectal projections in vivo: a-b: Regions of the brain can be differentially targeted by sliding the embryo in the main channel (compare upper and lower panels in a). When the caudal part of the head was exposed, most of the optic pathway was electroporated (b). c-e: The transfected...
PMC2147051_pone-0001376-g006_15435.jpg
What is being portrayed in this visual content?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15439.jpg
What does this image primarily show?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15438.jpg
What can you see in this picture?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15443.jpg
What's the most prominent thing you notice in this picture?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15436.jpg
What is the principal component of this image?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15440.jpg
What key item or scene is captured in this photo?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15434.jpg
What is the main focus of this visual representation?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15432.jpg
Describe the main subject of this image.
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2147051_pone-0001376-g006_15437.jpg
What stands out most in this visual?
SPC from N-4YSyn immunized B10.BR mice exacerbate MPTP-induced dopaminergic neurodegeneration and induce microglial responses in the SNpc.Photomicrographs from VMB sections stained with Fluoro-Jade C (left and middle panels) and Mac-1 antibody (right panels). PBS controls (PBS/none) exhibit an absence of Fluoro-Jade C ...
PMC2148063_F7_15446.jpg
What stands out most in this visual?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15452.jpg
What can you see in this picture?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15451.jpg
What is the core subject represented in this visual?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15455.jpg
What object or scene is depicted here?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15453.jpg
What can you see in this picture?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15445.jpg
What is being portrayed in this visual content?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15456.jpg
What is the dominant medical problem in this image?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148063_F7_15447.jpg
What does this image primarily show?
DSXM expression during spermatogenesis. (A-D) Larval testis immunofluorescence using (A) anti-DSXM, (B) anti-TJ, and (C) anti-EYA. (D) Merged images A-C. (E-H) Higher magnification view of A-D. (I-L) Adult apical testis immunofluorescence using (I) anti-DSXM, (J) anti-TJ and (K) anti-EYA. (L) Merged images I-K. (M-P) H...
PMC2148066_F2_15465.jpg
What stands out most in this visual?
Macro- and microscopic analysis of the fasting intestine. A) Change in whole-body and intestinal weight during fasting as percentage of the control. Asterisks label significant changes in weight compared to the fed condition. The line represents the daily percentual change in body weight. B) Histology of representative...
PMC2148066_F2_15467.jpg
What is shown in this image?
Macro- and microscopic analysis of the fasting intestine. A) Change in whole-body and intestinal weight during fasting as percentage of the control. Asterisks label significant changes in weight compared to the fed condition. The line represents the daily percentual change in body weight. B) Histology of representative...
PMC2148066_F2_15464.jpg
What stands out most in this visual?
Macro- and microscopic analysis of the fasting intestine. A) Change in whole-body and intestinal weight during fasting as percentage of the control. Asterisks label significant changes in weight compared to the fed condition. The line represents the daily percentual change in body weight. B) Histology of representative...