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PMC2164958_F6_15592.jpg | What can you see in this picture? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F6_15587.jpg | What is the core subject represented in this visual? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F6_15588.jpg | What's the most prominent thing you notice in this picture? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F6_15590.jpg | What is the central feature of this picture? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F6_15589.jpg | What is the central feature of this picture? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F6_15591.jpg | Can you identify the primary element in this image? | Histological changes in spleens of mice infected with 'scid-adapted' MARV. Scid mice were challenged IP with 1000 pfu of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-G) Tissues from the MARV-infected mice were stained with hematoxylin and eosin... |
PMC2164958_F8_15599.jpg | Describe the main subject of this image. | Progression of histologic lesions within the mesenteric lymph nodes of mice infected with "scid-adapted" MARV. Scid mice were challenged intraperitoneally with 1000 plaque-forming units of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-F) Tissues... |
PMC2164958_F8_15595.jpg | What is the principal component of this image? | Progression of histologic lesions within the mesenteric lymph nodes of mice infected with "scid-adapted" MARV. Scid mice were challenged intraperitoneally with 1000 plaque-forming units of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-F) Tissues... |
PMC2164958_F8_15598.jpg | What is the main focus of this visual representation? | Progression of histologic lesions within the mesenteric lymph nodes of mice infected with "scid-adapted" MARV. Scid mice were challenged intraperitoneally with 1000 plaque-forming units of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-F) Tissues... |
PMC2164958_F8_15600.jpg | What does this image primarily show? | Progression of histologic lesions within the mesenteric lymph nodes of mice infected with "scid-adapted" MARV. Scid mice were challenged intraperitoneally with 1000 plaque-forming units of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-F) Tissues... |
PMC2164958_F8_15596.jpg | Can you identify the primary element in this image? | Progression of histologic lesions within the mesenteric lymph nodes of mice infected with "scid-adapted" MARV. Scid mice were challenged intraperitoneally with 1000 plaque-forming units of 'scid-adapted' MARV-Ci67 and tissue samples were collected on days 0, 2, 4, 6, and 8 after challenge (n = 4–5/group). (A-F) Tissues... |
PMC2164959_F5_15602.jpg | What is the central feature of this picture? | Co-localization of HPV16 E5 with calnexin. HaCaT cells were transfected with AU1- tagged codon-optimised E5 or pEGFP-E5 and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and/or polyclonal anti-calnexin Abs. |
PMC2164959_F5_15601.jpg | What object or scene is depicted here? | Co-localization of HPV16 E5 with calnexin. HaCaT cells were transfected with AU1- tagged codon-optimised E5 or pEGFP-E5 and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and/or polyclonal anti-calnexin Abs. |
PMC2164959_F5_15604.jpg | What does this image primarily show? | Co-localization of HPV16 E5 with calnexin. HaCaT cells were transfected with AU1- tagged codon-optimised E5 or pEGFP-E5 and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and/or polyclonal anti-calnexin Abs. |
PMC2164959_F5_15603.jpg | What is shown in this image? | Co-localization of HPV16 E5 with calnexin. HaCaT cells were transfected with AU1- tagged codon-optimised E5 or pEGFP-E5 and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and/or polyclonal anti-calnexin Abs. |
PMC2164959_F5_15605.jpg | What is shown in this image? | Co-localization of HPV16 E5 with calnexin. HaCaT cells were transfected with AU1- tagged codon-optimised E5 or pEGFP-E5 and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and/or polyclonal anti-calnexin Abs. |
PMC2164959_F8_15616.jpg | What's the most prominent thing you notice in this picture? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164959_F8_15612.jpg | What is the principal component of this image? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164959_F8_15609.jpg | What is the core subject represented in this visual? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164959_F8_15610.jpg | What is the core subject represented in this visual? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164959_F8_15607.jpg | What is the central feature of this picture? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164959_F8_15614.jpg | What is the principal component of this image? | HPV16 E5, M2 and M3 mutants but not M1 mutant strongly co-localize with calnexin. HaCaT cells were transfected with A) AU1-tagged codon-optimised E5 or AU1- tagged codonoptimised E5 mutants M1 B), M2 C), and M3 D) and analysed after 24 h by confocal laser scanning microscopy using a monoclonal anti-AU1 and polyclonal a... |
PMC2164961_F3_15618.jpg | What is the core subject represented in this visual? | Abdominal CT image of slightly more distal of figure 2 shows multiple, mesenteric (white small arrows) and retroperitoneal (black arrows), well-defined, homogenous, solid masses. There is also grade 3 hydronephrosis in the left kidney (white arrowhead) |
PMC2164961_F6_15620.jpg | What is the main focus of this visual representation? | In microscopic appearance of histopathologic analyses, GIST cells have paler eosinophilic cytoplasm with indistinct cell margins and minimal tumor stroma (H&E, W200). |
PMC2164961_F7_15621.jpg | What's the most prominent thing you notice in this picture? | In microscopic appearance of immunohistochemical analyses, CD117 immunoreactivity is shown as diffuse strong cytoplasmic staining in spindle cell (CD117 immunostain, W200). |
PMC2164961_F8_15622.jpg | What's the most prominent thing you notice in this picture? | Microscopic appearances of immunohistochemical analyses. Approximately 15% of tumor cells show nuclear positivity for Ki-67 (MIB-1) (arrows) (Ki-67 immunostain, ×200). |
PMC2164962_F1_15623.jpg | Describe the main subject of this image. | CT scan showing the presence of a large, heterogenous, solid/cystic serosal based pelvic mass (arrows). |
PMC2164968_pone-0001397-g003_15627.jpg | What is the focal point of this photograph? | UCP-3 is expressed in human islets.A Human UCP-2, UCP-3 and α-tubulin mRNA expression in human islets. B Human islets were cultured at 5.5 or 11 mM glucose, and total protein extracts were analyzed on a western blot using UCP-3 antibodies. The intensities of the protein signal were quantified by scanning of images; blo... |
PMC2164968_pone-0001397-g003_15625.jpg | What is the main focus of this visual representation? | UCP-3 is expressed in human islets.A Human UCP-2, UCP-3 and α-tubulin mRNA expression in human islets. B Human islets were cultured at 5.5 or 11 mM glucose, and total protein extracts were analyzed on a western blot using UCP-3 antibodies. The intensities of the protein signal were quantified by scanning of images; blo... |
PMC2169208_F3_15629.jpg | What is the focal point of this photograph? | Transthoracic echocardiography showing left ventricular thrombus (arrow). |
PMC2169208_F4_15631.jpg | What object or scene is depicted here? | Computed tomography scan showing biventricular thrombi (white arrow) and a low attenuation lesion in the right lobe of the liver (black arrow). |
PMC2169208_F5_15630.jpg | What's the most prominent thing you notice in this picture? | Abdominal computed tomography scan showing multiple wedge defects in both kidneys. |
PMC2169220_F5_15632.jpg | What is the main focus of this visual representation? | TGFβ1 overexpression induces pronounced fibrotic response following bleomycin exposure. Tissue fibrosis was assessed in both Tr- wild type (A) and Tr+ transgenic (B) mice lung following exposure to 4500 IU bleomycin, as previously described. Shown are representative micrographs following haematoxylin/eosin staining of ... |
PMC2169232_F3_15639.jpg | What can you see in this picture? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15643.jpg | What key item or scene is captured in this photo? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15638.jpg | What stands out most in this visual? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15637.jpg | Describe the main subject of this image. | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15636.jpg | What is the central feature of this picture? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15642.jpg | What key item or scene is captured in this photo? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169232_F3_15640.jpg | What is the dominant medical problem in this image? | Ultrastructural analysis of the inner retina blood supply in zebrafish. A: Light microscopy image of blood vessels (highlighted by a red square) overlying the inner limiting membrane (ILM) of the retina in adult zebrafish. 40× magnification. B: Ultrastructure of capillary. The basal lamina (BL) is in contact with the I... |
PMC2169238_F1_15644.jpg | What is the main focus of this visual representation? | Typical CT scan and 3D reconstruction of patient suffering from an AAA. On the left shows a typical CT scan after segmentation using Mimics v10.0, with the ILT (red) and lumen (yellow) clearly distinguishable. 3D reconstruction of examined AAA is shown on right. |
PMC2169238_F2_15647.jpg | What does this image primarily show? | Effect of axial smoothing on the polylines constructed from the CT scans. Model 1 consists of 7 control points, Model 2 has 20 control points, Model 3 has 50 control points, and Model 4 has 70 control points per polylines slice. Green line is the original polyline from the CT scan slice, with the red line being the new... |
PMC2169242_F2_15664.jpg | What object or scene is depicted here? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15662.jpg | What is the dominant medical problem in this image? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15658.jpg | What is the principal component of this image? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15653.jpg | What object or scene is depicted here? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15660.jpg | What is shown in this image? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15654.jpg | What is the core subject represented in this visual? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15663.jpg | What is being portrayed in this visual content? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15657.jpg | Can you identify the primary element in this image? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15667.jpg | Describe the main subject of this image. | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15666.jpg | What object or scene is depicted here? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15661.jpg | What is the principal component of this image? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F2_15656.jpg | What does this image primarily show? | Lectin binding to upper and lower respiratory tract. Tissue distribution of Sambucus nigra agglutinin (SNA) for SAα2,6, Maackia amurensis agglutinin 1 (MAA1), and Maackia amurensis agglutinin 2 (MAA2) for SAα2,3 binding in the adult and paediatric respiratory tract. Serial sections of nasopharynx (A-C), adult bronchus ... |
PMC2169242_F3_15650.jpg | What does this image primarily show? | Lectin binding to bronchial epithelium using different detection methods. Serial sections for comparison of detection methods for lectin binding of Sambucus nigra agglutinin (SNA) to SAα2,6 and Maackia amurensis (MAA) agglutinin for binding to SAα2,3 in adult bronchial epithelium. Double fluoresecence for FITC labelled... |
PMC2169242_F3_15648.jpg | What is the focal point of this photograph? | Lectin binding to bronchial epithelium using different detection methods. Serial sections for comparison of detection methods for lectin binding of Sambucus nigra agglutinin (SNA) to SAα2,6 and Maackia amurensis (MAA) agglutinin for binding to SAα2,3 in adult bronchial epithelium. Double fluoresecence for FITC labelled... |
PMC2169242_F3_15649.jpg | What can you see in this picture? | Lectin binding to bronchial epithelium using different detection methods. Serial sections for comparison of detection methods for lectin binding of Sambucus nigra agglutinin (SNA) to SAα2,6 and Maackia amurensis (MAA) agglutinin for binding to SAα2,3 in adult bronchial epithelium. Double fluoresecence for FITC labelled... |
PMC2169242_F3_15651.jpg | What is the dominant medical problem in this image? | Lectin binding to bronchial epithelium using different detection methods. Serial sections for comparison of detection methods for lectin binding of Sambucus nigra agglutinin (SNA) to SAα2,6 and Maackia amurensis (MAA) agglutinin for binding to SAα2,3 in adult bronchial epithelium. Double fluoresecence for FITC labelled... |
PMC2169242_F3_15652.jpg | What is the principal component of this image? | Lectin binding to bronchial epithelium using different detection methods. Serial sections for comparison of detection methods for lectin binding of Sambucus nigra agglutinin (SNA) to SAα2,6 and Maackia amurensis (MAA) agglutinin for binding to SAα2,3 in adult bronchial epithelium. Double fluoresecence for FITC labelled... |
PMC2169242_F4_15670.jpg | What is being portrayed in this visual content? | Comparison of MAA binding using MAA from different suppliers. Serial sections of adult lung tissue for comparison of lectin binding of Maackia amurensis (MAA) for SAα2,3Gal. Biotin conjugated MAA1(also known as MAL) from Vector Laboratories (A) and (E), Biotin conjugated MAA2 (also known as MAH) from Vector Laboratorie... |
PMC2169242_F4_15674.jpg | What key item or scene is captured in this photo? | Comparison of MAA binding using MAA from different suppliers. Serial sections of adult lung tissue for comparison of lectin binding of Maackia amurensis (MAA) for SAα2,3Gal. Biotin conjugated MAA1(also known as MAL) from Vector Laboratories (A) and (E), Biotin conjugated MAA2 (also known as MAH) from Vector Laboratorie... |
PMC2169242_F4_15671.jpg | Describe the main subject of this image. | Comparison of MAA binding using MAA from different suppliers. Serial sections of adult lung tissue for comparison of lectin binding of Maackia amurensis (MAA) for SAα2,3Gal. Biotin conjugated MAA1(also known as MAL) from Vector Laboratories (A) and (E), Biotin conjugated MAA2 (also known as MAH) from Vector Laboratorie... |
PMC2169242_F4_15668.jpg | What's the most prominent thing you notice in this picture? | Comparison of MAA binding using MAA from different suppliers. Serial sections of adult lung tissue for comparison of lectin binding of Maackia amurensis (MAA) for SAα2,3Gal. Biotin conjugated MAA1(also known as MAL) from Vector Laboratories (A) and (E), Biotin conjugated MAA2 (also known as MAH) from Vector Laboratorie... |
PMC2169242_F4_15672.jpg | What is being portrayed in this visual content? | Comparison of MAA binding using MAA from different suppliers. Serial sections of adult lung tissue for comparison of lectin binding of Maackia amurensis (MAA) for SAα2,3Gal. Biotin conjugated MAA1(also known as MAL) from Vector Laboratories (A) and (E), Biotin conjugated MAA2 (also known as MAH) from Vector Laboratorie... |
PMC2169301_pone-0001409-g005_15684.jpg | What is the dominant medical problem in this image? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15689.jpg | What key item or scene is captured in this photo? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15686.jpg | What is the principal component of this image? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15685.jpg | What object or scene is depicted here? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15679.jpg | What stands out most in this visual? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15682.jpg | Describe the main subject of this image. | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15678.jpg | What is the central feature of this picture? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15687.jpg | What's the most prominent thing you notice in this picture? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15690.jpg | What object or scene is depicted here? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15681.jpg | What is being portrayed in this visual content? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g005_15683.jpg | What is the main focus of this visual representation? | Apparently structurally normal, intact dividing and viable S. aureus Newman cells persist in the intracellular vacuolar compartment on four consecutive days post-phagocytosis.The photographs presented are representative of a minimum of 20 fields observed. hMDMs were allowed to engulf bacteria for 2h at a MOI of 25, and... |
PMC2169301_pone-0001409-g007_15676.jpg | What key item or scene is captured in this photo? | An α-hemolysin mutant of S. aureus strain Newman is efficiently killed in phago(lyso)somes within two days of phagocytosis.Intracellular persistence of S. aureus was determined as described in the legend of Fig. 3A. Bars represent mean CFU values ±SD and are representative of at least three separate experiments, perfor... |
PMC2169302_pone-0001414-g002_15693.jpg | What is shown in this image? | Tissue specific expression of Dnmt2.(A) Left panel: developmental Western blot of pGeno-Dnmt2-EGFP animals. Whole protein extract from embryonic, larval and adult stages were blotted and probed with anti-Dnmt2. Ponceau staining is shown as a loading control. Right panel: Dnmt2-EGFP is expressed both in the cytoplasm an... |
PMC2169302_pone-0001414-g002_15691.jpg | Describe the main subject of this image. | Tissue specific expression of Dnmt2.(A) Left panel: developmental Western blot of pGeno-Dnmt2-EGFP animals. Whole protein extract from embryonic, larval and adult stages were blotted and probed with anti-Dnmt2. Ponceau staining is shown as a loading control. Right panel: Dnmt2-EGFP is expressed both in the cytoplasm an... |
PMC2169302_pone-0001414-g002_15695.jpg | What is shown in this image? | Tissue specific expression of Dnmt2.(A) Left panel: developmental Western blot of pGeno-Dnmt2-EGFP animals. Whole protein extract from embryonic, larval and adult stages were blotted and probed with anti-Dnmt2. Ponceau staining is shown as a loading control. Right panel: Dnmt2-EGFP is expressed both in the cytoplasm an... |
PMC2169302_pone-0001414-g002_15694.jpg | What is the main focus of this visual representation? | Tissue specific expression of Dnmt2.(A) Left panel: developmental Western blot of pGeno-Dnmt2-EGFP animals. Whole protein extract from embryonic, larval and adult stages were blotted and probed with anti-Dnmt2. Ponceau staining is shown as a loading control. Right panel: Dnmt2-EGFP is expressed both in the cytoplasm an... |
PMC2169302_pone-0001414-g006_15705.jpg | What does this image primarily show? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15712.jpg | What can you see in this picture? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15710.jpg | Can you identify the primary element in this image? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15703.jpg | What is being portrayed in this visual content? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15704.jpg | What is the main focus of this visual representation? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15706.jpg | What does this image primarily show? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15708.jpg | Can you identify the primary element in this image? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15700.jpg | What can you see in this picture? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2169302_pone-0001414-g006_15707.jpg | What object or scene is depicted here? | Nuclear access reporter assay using GAL4:VP16-Dnmt2 fusion proteins.(A) Schematic representation of the nuclear access reporter assay. Ubiquitous expression of the GAL4:VP16 (GV) fusion proteins (black bar) causes the expression of EGFP only in some cells (green) due to selective nuclear access of the fusion protein. (... |
PMC2170320_fig01_15715.jpg | What is the dominant medical problem in this image? | Localization of MurG in wild-type E. coli LMC500 (A) and in the MurG(Ts) strain GS58 (B and C). Phase-contrast images are given on the left and fluorescence images on the right. LMC500 cells were grown to steady state at 28°C in GB1 (A), fixed, permeabilized and immunolabelled with anti-MurG. GS58 cells were first grow... |
PMC2170320_fig01_15714.jpg | What's the most prominent thing you notice in this picture? | Localization of MurG in wild-type E. coli LMC500 (A) and in the MurG(Ts) strain GS58 (B and C). Phase-contrast images are given on the left and fluorescence images on the right. LMC500 cells were grown to steady state at 28°C in GB1 (A), fixed, permeabilized and immunolabelled with anti-MurG. GS58 cells were first grow... |
PMC2170320_fig01_15717.jpg | What does this image primarily show? | Localization of MurG in wild-type E. coli LMC500 (A) and in the MurG(Ts) strain GS58 (B and C). Phase-contrast images are given on the left and fluorescence images on the right. LMC500 cells were grown to steady state at 28°C in GB1 (A), fixed, permeabilized and immunolabelled with anti-MurG. GS58 cells were first grow... |
PMC2170320_fig01_15718.jpg | What is shown in this image? | Localization of MurG in wild-type E. coli LMC500 (A) and in the MurG(Ts) strain GS58 (B and C). Phase-contrast images are given on the left and fluorescence images on the right. LMC500 cells were grown to steady state at 28°C in GB1 (A), fixed, permeabilized and immunolabelled with anti-MurG. GS58 cells were first grow... |
PMC2170320_fig01_15716.jpg | What object or scene is depicted here? | Localization of MurG in wild-type E. coli LMC500 (A) and in the MurG(Ts) strain GS58 (B and C). Phase-contrast images are given on the left and fluorescence images on the right. LMC500 cells were grown to steady state at 28°C in GB1 (A), fixed, permeabilized and immunolabelled with anti-MurG. GS58 cells were first grow... |
PMC2170320_fig06_15719.jpg | What can you see in this picture? | Localization of MreB in the MurG(Ts) strain GS58 grown at the restrictive temperature (42°C) in TY for 2 MDs (A). The MreB helical structure was maintained in the absence of the functional full-length MurG protein. (See for MurG localization in these cells Fig. 1C.) MurG localization in the absence of MreB helix (B). I... |
PMC2170320_fig06_15724.jpg | Describe the main subject of this image. | Localization of MreB in the MurG(Ts) strain GS58 grown at the restrictive temperature (42°C) in TY for 2 MDs (A). The MreB helical structure was maintained in the absence of the functional full-length MurG protein. (See for MurG localization in these cells Fig. 1C.) MurG localization in the absence of MreB helix (B). I... |
PMC2170320_fig06_15720.jpg | What is the central feature of this picture? | Localization of MreB in the MurG(Ts) strain GS58 grown at the restrictive temperature (42°C) in TY for 2 MDs (A). The MreB helical structure was maintained in the absence of the functional full-length MurG protein. (See for MurG localization in these cells Fig. 1C.) MurG localization in the absence of MreB helix (B). I... |
PMC2170320_fig07_15730.jpg | What is being portrayed in this visual content? | MurG and MreB localization are independent of the spherical cell morphology (A and B). LMC500 cells were grown for 2 MDs in the presence of mecillinam (inhibitor of PBP2), at 28°C in GB1. Cells were immunolabelled with anti-MreB (A) or anti-MurG (B). The MreB helical structure is preserved and the multi-foci localizati... |
PMC2170320_fig07_15728.jpg | What is the focal point of this photograph? | MurG and MreB localization are independent of the spherical cell morphology (A and B). LMC500 cells were grown for 2 MDs in the presence of mecillinam (inhibitor of PBP2), at 28°C in GB1. Cells were immunolabelled with anti-MreB (A) or anti-MurG (B). The MreB helical structure is preserved and the multi-foci localizati... |
PMC2170320_fig07_15729.jpg | Can you identify the primary element in this image? | MurG and MreB localization are independent of the spherical cell morphology (A and B). LMC500 cells were grown for 2 MDs in the presence of mecillinam (inhibitor of PBP2), at 28°C in GB1. Cells were immunolabelled with anti-MreB (A) or anti-MurG (B). The MreB helical structure is preserved and the multi-foci localizati... |
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