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PMC2200863_pone-0001510-g007_16146.jpg | What is the main focus of this visual representation? | Light signaling in the regulation of PIN2 intracellular distribution.(A) PIN2-eGFP was localized at the apical PM of root epidermal cells of plants grown in continuous white light. (B) PIN2-eGFP asymmetric location in root epidermis cells was maintained in light-grown plants shifted to continuous blue light (475 nm) fo... |
PMC2202780_fig1_16160.jpg | What can you see in this picture? | Computed tomographic (CT) scan showing a high-grade liver injury along with large amount of intraperitoneal fluid in the upper abdomen. |
PMC2203974_F2_16161.jpg | What is being portrayed in this visual content? | Computed tomography scan of chest (case no. 2) demonstrating a radiolucent lesion of the right anterior second rib with cortical bubbling or blebbing, and without radiographic evidence of an acute fracture, calcification or malignancy (arrow). R indicates right side. |
PMC2203975_F1_16163.jpg | What is being portrayed in this visual content? | Transthoracic echocardiogram showing left ventricle long and short axis views before iloprost nebulization. This echocardiography reveals the severe right ventricular dilatation and hypertrophy. As the right ventricle undergoes dilation and hypertrophy, its crescentic shape is lost and the septum shifts leftward compre... |
PMC2203975_F2_16167.jpg | What is the principal component of this image? | Transthoracic echocardiogram showing left ventricle long and short axis views after iloprost nebulization. In the echocardiographic evaluation after iloprost administration we can detect a reduction in right ventricular dimension, with a proportional increase in left ventricular dimension and performance. The correctio... |
PMC2203975_F2_16166.jpg | What is the focal point of this photograph? | Transthoracic echocardiogram showing left ventricle long and short axis views after iloprost nebulization. In the echocardiographic evaluation after iloprost administration we can detect a reduction in right ventricular dimension, with a proportional increase in left ventricular dimension and performance. The correctio... |
PMC2203977_F1_16165.jpg | What's the most prominent thing you notice in this picture? | Measurement of lung volumes by a semi-automated computerized method of delineating the lungs and summing cross-sectional areas. (a) On the coronal image of the lung, threshold signal intensity is selected to highlight the air in green (lung). (b) The total lung volume is calculated by summating the volume of all corona... |
PMC2203977_F2_16169.jpg | What is the core subject represented in this visual? | Measurement of AP and TS diameter of the chest wall on the reformatted axial image. (a) Upper level at the carina (C), maximal inspiratory image. (b) Lower level at the apical vertebra (A), maximal inspiratory image. Tangential lines are drawn to the anterior, posterior and lateral lung surfaces. The chest wall dimensi... |
PMC2203977_F2_16168.jpg | What stands out most in this visual? | Measurement of AP and TS diameter of the chest wall on the reformatted axial image. (a) Upper level at the carina (C), maximal inspiratory image. (b) Lower level at the apical vertebra (A), maximal inspiratory image. Tangential lines are drawn to the anterior, posterior and lateral lung surfaces. The chest wall dimensi... |
PMC2203990_F4_16176.jpg | What does this image primarily show? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16173.jpg | What is the central feature of this picture? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16172.jpg | What object or scene is depicted here? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16175.jpg | What is the main focus of this visual representation? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16170.jpg | What is the principal component of this image? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16171.jpg | What is the central feature of this picture? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16174.jpg | What is being portrayed in this visual content? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203990_F4_16177.jpg | What is the principal component of this image? | SP-D immunostaining of rat prostate tissue. Rats were either sham-infected or infected with E. coli. Prostates were removed 24, 48, and 72 hours post-infection. Photographs in the left column are SP-D immunostaining and the corresponding photograph on the right is the same tissue immunostained using normal rabbit IgG a... |
PMC2203993_F3_16195.jpg | What key item or scene is captured in this photo? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16192.jpg | What's the most prominent thing you notice in this picture? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16186.jpg | Describe the main subject of this image. | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16188.jpg | What is the main focus of this visual representation? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16185.jpg | What is the core subject represented in this visual? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16184.jpg | What is being portrayed in this visual content? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16187.jpg | What can you see in this picture? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16190.jpg | What is the dominant medical problem in this image? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16193.jpg | What is being portrayed in this visual content? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F3_16191.jpg | What's the most prominent thing you notice in this picture? | Comparison of Turtle and Padlock Probes in FFPE cells. Representative results of RNA detection with both Turtle and Padlock Probes in cells treated similarly to pathological routine specimens (fixed in formalin and embedded in paraffin). The counterstain is DAPI producing blue cell nuclei. A-F) Detection of 5S rRNA (gr... |
PMC2203993_F4_16182.jpg | What is the central feature of this picture? | Detection of RNA in FFPE tissue. Representative results of RNA detection in FFPE human tissue from an anonymous patient with Epstein-Barr Virus (EBV)-associated Hodgkin's lymphoma. EBER1 RNA should appear in the neoplastic Reed-Sternberg cells and not in the surrounding lymphocytes. The counterstain is DAPI, producing ... |
PMC2203993_F4_16180.jpg | What is the focal point of this photograph? | Detection of RNA in FFPE tissue. Representative results of RNA detection in FFPE human tissue from an anonymous patient with Epstein-Barr Virus (EBV)-associated Hodgkin's lymphoma. EBER1 RNA should appear in the neoplastic Reed-Sternberg cells and not in the surrounding lymphocytes. The counterstain is DAPI, producing ... |
PMC2203993_F4_16178.jpg | What key item or scene is captured in this photo? | Detection of RNA in FFPE tissue. Representative results of RNA detection in FFPE human tissue from an anonymous patient with Epstein-Barr Virus (EBV)-associated Hodgkin's lymphoma. EBER1 RNA should appear in the neoplastic Reed-Sternberg cells and not in the surrounding lymphocytes. The counterstain is DAPI, producing ... |
PMC2203993_F4_16181.jpg | What is the dominant medical problem in this image? | Detection of RNA in FFPE tissue. Representative results of RNA detection in FFPE human tissue from an anonymous patient with Epstein-Barr Virus (EBV)-associated Hodgkin's lymphoma. EBER1 RNA should appear in the neoplastic Reed-Sternberg cells and not in the surrounding lymphocytes. The counterstain is DAPI, producing ... |
PMC2203993_F4_16183.jpg | What is the dominant medical problem in this image? | Detection of RNA in FFPE tissue. Representative results of RNA detection in FFPE human tissue from an anonymous patient with Epstein-Barr Virus (EBV)-associated Hodgkin's lymphoma. EBER1 RNA should appear in the neoplastic Reed-Sternberg cells and not in the surrounding lymphocytes. The counterstain is DAPI, producing ... |
PMC2203997_F1_16198.jpg | What stands out most in this visual? | MRI shows a tumor with two components of high T1-weighted (a) and high T2-weighted images (b) (right portion; well-differentiated components), and of low T1-weighted (a) and high T2-weighted images (b) (left portion; dedifferentiated components). Well-differentiated components and dedifferentiated components with a dis... |
PMC2203997_F1_16197.jpg | What is the core subject represented in this visual? | MRI shows a tumor with two components of high T1-weighted (a) and high T2-weighted images (b) (right portion; well-differentiated components), and of low T1-weighted (a) and high T2-weighted images (b) (left portion; dedifferentiated components). Well-differentiated components and dedifferentiated components with a dis... |
PMC2203997_F1_16200.jpg | What is the main focus of this visual representation? | MRI shows a tumor with two components of high T1-weighted (a) and high T2-weighted images (b) (right portion; well-differentiated components), and of low T1-weighted (a) and high T2-weighted images (b) (left portion; dedifferentiated components). Well-differentiated components and dedifferentiated components with a dis... |
PMC2203997_F1_16201.jpg | What is the principal component of this image? | MRI shows a tumor with two components of high T1-weighted (a) and high T2-weighted images (b) (right portion; well-differentiated components), and of low T1-weighted (a) and high T2-weighted images (b) (left portion; dedifferentiated components). Well-differentiated components and dedifferentiated components with a dis... |
PMC2203997_F1_16199.jpg | What is the main focus of this visual representation? | MRI shows a tumor with two components of high T1-weighted (a) and high T2-weighted images (b) (right portion; well-differentiated components), and of low T1-weighted (a) and high T2-weighted images (b) (left portion; dedifferentiated components). Well-differentiated components and dedifferentiated components with a dis... |
PMC2203998_F1_16196.jpg | What is being portrayed in this visual content? | The anterior view of the conventional lymphoscintigraphy shows one SLN indicated by the yellow arrow. The purple arrow indicates the injection site. |
PMC2203999_F4_16204.jpg | Describe the main subject of this image. | (a) Electron microscopic image of tumours of BP-4 group at a magnification of × 710. Obviously there are numerous apoptotic cells with condensed nucleus (arrow) (b)Transmission electron microscopic imaging showing apoptotic cells which are seen as apoptotic bodies (arrow) with a shrunken nucleus and a condensed cytopla... |
PMC2203999_F4_16203.jpg | What is the principal component of this image? | (a) Electron microscopic image of tumours of BP-4 group at a magnification of × 710. Obviously there are numerous apoptotic cells with condensed nucleus (arrow) (b)Transmission electron microscopic imaging showing apoptotic cells which are seen as apoptotic bodies (arrow) with a shrunken nucleus and a condensed cytopla... |
PMC2203999_F4_16202.jpg | What is the main focus of this visual representation? | (a) Electron microscopic image of tumours of BP-4 group at a magnification of × 710. Obviously there are numerous apoptotic cells with condensed nucleus (arrow) (b)Transmission electron microscopic imaging showing apoptotic cells which are seen as apoptotic bodies (arrow) with a shrunken nucleus and a condensed cytopla... |
PMC2204009_F3_16208.jpg | What is being portrayed in this visual content? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16207.jpg | What is the principal component of this image? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16212.jpg | What is the focal point of this photograph? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16206.jpg | What is the focal point of this photograph? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16210.jpg | What is the dominant medical problem in this image? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16211.jpg | Can you identify the primary element in this image? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F3_16214.jpg | What stands out most in this visual? | Early Otx2-GFP expression in epiblast and AVE. a. GFP fluorescence and transmission observations of Otx2+/OG and control Otx2+/+ embryos at E6.5 and E7.5. Anterior is leftward. Scale bars: 100 μm. b. Direct visualisation of GFP fluorescence (green) and immunofluorescent staining of F-actin (Phalloidin – red) and DNA (H... |
PMC2204009_F4_16217.jpg | Can you identify the primary element in this image? | Dynamics of Otx2-GFP expression at mid-gestation. Direct visualisation of GFP fluorescence of Otx2+/OG embryos and one control Otx2+/+ E11.5 embryo (a-d) versus Otx2 mRNA localisation detected by whole-mount in situ hybridization on Otx2+/+animals (e-h) at indicated stages. Anterior is leftward. The arrow indicates the... |
PMC2204009_F4_16220.jpg | Can you identify the primary element in this image? | Dynamics of Otx2-GFP expression at mid-gestation. Direct visualisation of GFP fluorescence of Otx2+/OG embryos and one control Otx2+/+ E11.5 embryo (a-d) versus Otx2 mRNA localisation detected by whole-mount in situ hybridization on Otx2+/+animals (e-h) at indicated stages. Anterior is leftward. The arrow indicates the... |
PMC2204009_F4_16219.jpg | What is shown in this image? | Dynamics of Otx2-GFP expression at mid-gestation. Direct visualisation of GFP fluorescence of Otx2+/OG embryos and one control Otx2+/+ E11.5 embryo (a-d) versus Otx2 mRNA localisation detected by whole-mount in situ hybridization on Otx2+/+animals (e-h) at indicated stages. Anterior is leftward. The arrow indicates the... |
PMC2204009_F4_16218.jpg | Describe the main subject of this image. | Dynamics of Otx2-GFP expression at mid-gestation. Direct visualisation of GFP fluorescence of Otx2+/OG embryos and one control Otx2+/+ E11.5 embryo (a-d) versus Otx2 mRNA localisation detected by whole-mount in situ hybridization on Otx2+/+animals (e-h) at indicated stages. Anterior is leftward. The arrow indicates the... |
PMC2204009_F5_16233.jpg | What can you see in this picture? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16236.jpg | What is the dominant medical problem in this image? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16237.jpg | What is the principal component of this image? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16239.jpg | Can you identify the primary element in this image? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16235.jpg | What is the principal component of this image? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16234.jpg | Describe the main subject of this image. | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F5_16240.jpg | What does this image primarily show? | Efficient Otx2-GFP detection during late-development and in adults. a-j. Direct visualisation of GFP fluorescence on 10μm thin section of E16.5 (a-d), P2 (e-h) and adult (i-j) Otx2+/OG animals. b-d. Magnifications of part delimitated by the corresponding red boxes in image a. f-h. Magnifications of part delimitated by ... |
PMC2204009_F6_16232.jpg | What object or scene is depicted here? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16227.jpg | What is the dominant medical problem in this image? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16231.jpg | What key item or scene is captured in this photo? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16225.jpg | What is the main focus of this visual representation? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16226.jpg | What object or scene is depicted here? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16228.jpg | What stands out most in this visual? | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204009_F6_16230.jpg | Describe the main subject of this image. | Regulated Otx2-GFP nuclear localization in adult retina. Confocal microscopy analysis. a, b. Direct visualisation of GFP fluorescence (green) and propidium iodide staining of DNA (red) on 10 μm thin section of Otx2+/OG (a) and control Otx2+/+ (b) adult retina. c-f". Localisation of Otx2-GFP (direct visualisation of GFP... |
PMC2204027_F1_16244.jpg | What object or scene is depicted here? | Left inferior parathyroid adenoma. Axial MR imaging scans (07/1998) weighted in T1 (A) and T2 (B) show a spontaneous hyperintense and well defined round lesion in both T1- and T2-weighted in the left-inferior parathyroid adenoma region (arrow). There is a hypointense lesion with a halo in the T2-weighted image which ca... |
PMC2204028_F4_16246.jpg | Can you identify the primary element in this image? | Small Bowel with H&E staining × 20 magnification: Carcinoid tumor penetrating the subserosa. |
PMC2204028_F5_16243.jpg | What is being portrayed in this visual content? | Lymph node with H&E staining ×4 magnification: Carcinoid metastases. |
PMC2204032_F1_16250.jpg | What is the dominant medical problem in this image? | NOD2 detection in coronary atherosclerotic lesions by immunofluorescence. Panel A depicts an overview of a coronary artery section with a plaque at low magnification (HE staining, original magnification ×5). The same section has been stained for NOD2 (FITC, green) and the macrophage marker CD68 (Cy3, red) in B. The ast... |
PMC2204051_pone-0001496-g003_16256.jpg | What does this image primarily show? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16251.jpg | What does this image primarily show? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16257.jpg | What stands out most in this visual? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16260.jpg | What is being portrayed in this visual content? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16252.jpg | What does this image primarily show? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16255.jpg | What is being portrayed in this visual content? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16258.jpg | What is the focal point of this photograph? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16259.jpg | What is the principal component of this image? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204051_pone-0001496-g003_16254.jpg | Can you identify the primary element in this image? | Electron micrographs of paracrystals formed by Rod mutants.Rods were dialyzed for 16 hrs against low salt buffer, stained with uranyl acetate and observed with the electron microscope. Bar on the left column, 1 µM. Bar on the right column, 0.1 µM. |
PMC2204052_pone-0001506-g002_16263.jpg | What does this image primarily show? | Limbic brain responses by 33 msec “unseen” cues in cocaine patients.Both cocaine (A) and sexual (B) cues produced activation in amygdala and ventral striatum/ventral pallidum/substantia innominata, and insula, as well as the OFC (OFC not shown). Statistical parametric t maps were generated by SPM 2; thresholded for dis... |
PMC2204052_pone-0001506-g002_16261.jpg | What's the most prominent thing you notice in this picture? | Limbic brain responses by 33 msec “unseen” cues in cocaine patients.Both cocaine (A) and sexual (B) cues produced activation in amygdala and ventral striatum/ventral pallidum/substantia innominata, and insula, as well as the OFC (OFC not shown). Statistical parametric t maps were generated by SPM 2; thresholded for dis... |
PMC2204065_pone-0001520-g001_16266.jpg | What can you see in this picture? | Late-EPCs can be cultured from peripheral blood mononuclear cells of patients with cKS.A representative phase-contrast photograph of a late-EPC colony, identified as a well-circumscribed monolayer of cobblestone-appearing cells, is shown. Similar colonies were obtained from 15 different patients. A) ×100 magnification,... |
PMC2204065_pone-0001520-g003_16268.jpg | What key item or scene is captured in this photo? | Late-EPCs obtained from patients with cKS form capillary-like structures in vitro.Late-EPCs cultured in Matrigel gave rise within 12 hours of incubation to vascular structures that were quite similar to those formed by control endothelial cell lines. A) A representative phase-contrast photograph of the capillary-like s... |
PMC2204065_pone-0001520-g003_16267.jpg | What object or scene is depicted here? | Late-EPCs obtained from patients with cKS form capillary-like structures in vitro.Late-EPCs cultured in Matrigel gave rise within 12 hours of incubation to vascular structures that were quite similar to those formed by control endothelial cell lines. A) A representative phase-contrast photograph of the capillary-like s... |
PMC2204067_pone-0001517-g001_16276.jpg | What does this image primarily show? | Long-term ectopic expression of GFP in neurogenic regions of the postnatal brain by electroporation.A. Animals immobilized by cooling are injected with plasmid using a dissecting microscope and picospritzer. The injection is made rostral to the olfactory bulb followed by a series of 5 voltage pulses delivered with twee... |
PMC2204067_pone-0001517-g001_16269.jpg | What can you see in this picture? | Long-term ectopic expression of GFP in neurogenic regions of the postnatal brain by electroporation.A. Animals immobilized by cooling are injected with plasmid using a dissecting microscope and picospritzer. The injection is made rostral to the olfactory bulb followed by a series of 5 voltage pulses delivered with twee... |
PMC2204067_pone-0001517-g001_16271.jpg | What is the central feature of this picture? | Long-term ectopic expression of GFP in neurogenic regions of the postnatal brain by electroporation.A. Animals immobilized by cooling are injected with plasmid using a dissecting microscope and picospritzer. The injection is made rostral to the olfactory bulb followed by a series of 5 voltage pulses delivered with twee... |
PMC2204067_pone-0001517-g001_16275.jpg | What does this image primarily show? | Long-term ectopic expression of GFP in neurogenic regions of the postnatal brain by electroporation.A. Animals immobilized by cooling are injected with plasmid using a dissecting microscope and picospritzer. The injection is made rostral to the olfactory bulb followed by a series of 5 voltage pulses delivered with twee... |
PMC2204067_pone-0001517-g001_16270.jpg | What is the central feature of this picture? | Long-term ectopic expression of GFP in neurogenic regions of the postnatal brain by electroporation.A. Animals immobilized by cooling are injected with plasmid using a dissecting microscope and picospritzer. The injection is made rostral to the olfactory bulb followed by a series of 5 voltage pulses delivered with twee... |
PMC2205998_F1_16277.jpg | What is shown in this image? | Photograph of the burn site on the day of surgery |
PMC2205998_F2_16278.jpg | What is the dominant medical problem in this image? | Computed tomography scan and plain film of the patient demonstrating the location of indwelling titanium hardware placed at prior surgery. The burn occurred on the right forehead directly over the most lateral piece of hardware visualized in the coronal section |
PMC2206006_F1_16281.jpg | What object or scene is depicted here? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16285.jpg | What is the main focus of this visual representation? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16284.jpg | What can you see in this picture? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16280.jpg | What is the focal point of this photograph? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16287.jpg | Can you identify the primary element in this image? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16282.jpg | What's the most prominent thing you notice in this picture? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16286.jpg | What key item or scene is captured in this photo? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206006_F1_16279.jpg | Can you identify the primary element in this image? | Expression of ETARs and ETBRs in rat dorsal root ganglion. Sections of lumbar rat dorsal root ganglion were analysed for the expression of ETARs (A) or ETBRs (B, C) using affinity-purified antibodies. For the identification of TRPV1-postive neurons co-staining with a TRPV1 antibody (A, B) was performed. Expression of E... |
PMC2206011_F5_16290.jpg | What does this image primarily show? | Efficacy of antibiotic treatment verified by FISH. Blochmannia specific fluorescent in situ hybridisation (FISH) of bacteriocytes (Bc) in the midgut epithelium of: (A) and (B) an untreated worker of C. floridanus, and (C) and (D) a worker treated with the antibiotic rifampicin and fed an artificial diet containing all ... |
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