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PMC2206011_F5_16288.jpg
What can you see in this picture?
Efficacy of antibiotic treatment verified by FISH. Blochmannia specific fluorescent in situ hybridisation (FISH) of bacteriocytes (Bc) in the midgut epithelium of: (A) and (B) an untreated worker of C. floridanus, and (C) and (D) a worker treated with the antibiotic rifampicin and fed an artificial diet containing all ...
PMC2206024_F2_16294.jpg
What stands out most in this visual?
Photomicrograph of bone defect grafted with Rhizoma Curculiginis extract in collagen matrix on day 14. New bone (N) can be seen spanning the defect. H: Host bone. Some collagen matrix (C) remained at the center of the bone defect (Periodic acid-Schiff stain; original magnification × 40).
PMC2206024_F2_16293.jpg
Describe the main subject of this image.
Photomicrograph of bone defect grafted with Rhizoma Curculiginis extract in collagen matrix on day 14. New bone (N) can be seen spanning the defect. H: Host bone. Some collagen matrix (C) remained at the center of the bone defect (Periodic acid-Schiff stain; original magnification × 40).
PMC2206024_F4_16297.jpg
What is the main focus of this visual representation?
Photomicrograph of bone defect grafted with collagen matrix (positive control) on day 14. No bone could be seen across the defect except a little new bone near the ends of the host bone (H). Collagen matrix (C) remained across the bone defect (Periodic acid-Schiff stain, original magnification × 40).
PMC2206024_F4_16296.jpg
What can you see in this picture?
Photomicrograph of bone defect grafted with collagen matrix (positive control) on day 14. No bone could be seen across the defect except a little new bone near the ends of the host bone (H). Collagen matrix (C) remained across the bone defect (Periodic acid-Schiff stain, original magnification × 40).
PMC2206024_F4_16298.jpg
What is the main focus of this visual representation?
Photomicrograph of bone defect grafted with collagen matrix (positive control) on day 14. No bone could be seen across the defect except a little new bone near the ends of the host bone (H). Collagen matrix (C) remained across the bone defect (Periodic acid-Schiff stain, original magnification × 40).
PMC2206024_F5_16295.jpg
What is being portrayed in this visual content?
Transmission electron micrographs show the area near the newly formed bone of bone defect grafted with Rhizoma Drynariae extract in collagen matrix. (F: mineralization front; OB: osteoblasts; OC: osteocytes; original magnification × 3500).
PMC2206042_F3_16301.jpg
What is the dominant medical problem in this image?
Castleman's disease (CD) infiltrating normal pancreatic tissue (P) (hematoxylin-eosin, original magnification × 100). Black arrow demonstrates infiltration of CD into normal pancreas.
PMC2206042_F3_16302.jpg
What's the most prominent thing you notice in this picture?
Castleman's disease (CD) infiltrating normal pancreatic tissue (P) (hematoxylin-eosin, original magnification × 100). Black arrow demonstrates infiltration of CD into normal pancreas.
PMC2206042_F4_16300.jpg
What is shown in this image?
Hyaline-vascular-CD. Involuting germinal center surrounded by concentric rings of small lymphocytes penetrated by hyalinized vessel (hematoxylin-eosin, original magnification × 400).
PMC2206344_F2_16307.jpg
What is the dominant medical problem in this image?
Expression of Fc gamma receptor (FcγR)IIb in healthy and rheumatoid arthritis (RA) synovia. (a) FcγRIIb was sparsely expressed in the few healthy synovial biopsies that were positively stained by GB3. The arrows indicate FcγRIIb positive cells in the sub-lining synovial layer and tissue. (b) The IgG1 isotype control an...
PMC2206344_F2_16309.jpg
What can you see in this picture?
Expression of Fc gamma receptor (FcγR)IIb in healthy and rheumatoid arthritis (RA) synovia. (a) FcγRIIb was sparsely expressed in the few healthy synovial biopsies that were positively stained by GB3. The arrows indicate FcγRIIb positive cells in the sub-lining synovial layer and tissue. (b) The IgG1 isotype control an...
PMC2206344_F2_16310.jpg
What is the dominant medical problem in this image?
Expression of Fc gamma receptor (FcγR)IIb in healthy and rheumatoid arthritis (RA) synovia. (a) FcγRIIb was sparsely expressed in the few healthy synovial biopsies that were positively stained by GB3. The arrows indicate FcγRIIb positive cells in the sub-lining synovial layer and tissue. (b) The IgG1 isotype control an...
PMC2206344_F2_16308.jpg
What is the core subject represented in this visual?
Expression of Fc gamma receptor (FcγR)IIb in healthy and rheumatoid arthritis (RA) synovia. (a) FcγRIIb was sparsely expressed in the few healthy synovial biopsies that were positively stained by GB3. The arrows indicate FcγRIIb positive cells in the sub-lining synovial layer and tissue. (b) The IgG1 isotype control an...
PMC2206344_F6_16303.jpg
Describe the main subject of this image.
Decreased Fc gamma receptor (FcγR) expression after local treatment with glucocorticoids. (a) Immunohistochemical staining of FcγRs and macrophages (CD163) in arthritic synovial tissue (n = 9) before and after local glucocorticoid treatment of the joint was analysed. The FcγRI expression was significantly decreased aft...
PMC2206378_F6_16313.jpg
What object or scene is depicted here?
Immunohistochemistry to assess glycosaminoglycan distribution. Cartilage sections immunohistochemically stained for (a,b) chondroitin-4-sulphate and (c,d) chondroitin-6-sulphate. Repair tissue from autologous chondrocyte implantation (ACI)-treated patients with the highest (a) (22-year-old) and lowest (b) (52-year-old)...
PMC2206378_F6_16311.jpg
What is the core subject represented in this visual?
Immunohistochemistry to assess glycosaminoglycan distribution. Cartilage sections immunohistochemically stained for (a,b) chondroitin-4-sulphate and (c,d) chondroitin-6-sulphate. Repair tissue from autologous chondrocyte implantation (ACI)-treated patients with the highest (a) (22-year-old) and lowest (b) (52-year-old)...
PMC2206378_F6_16314.jpg
What stands out most in this visual?
Immunohistochemistry to assess glycosaminoglycan distribution. Cartilage sections immunohistochemically stained for (a,b) chondroitin-4-sulphate and (c,d) chondroitin-6-sulphate. Repair tissue from autologous chondrocyte implantation (ACI)-treated patients with the highest (a) (22-year-old) and lowest (b) (52-year-old)...
PMC2206378_F6_16312.jpg
What can you see in this picture?
Immunohistochemistry to assess glycosaminoglycan distribution. Cartilage sections immunohistochemically stained for (a,b) chondroitin-4-sulphate and (c,d) chondroitin-6-sulphate. Repair tissue from autologous chondrocyte implantation (ACI)-treated patients with the highest (a) (22-year-old) and lowest (b) (52-year-old)...
PMC2206390_F5_16315.jpg
What is the focal point of this photograph?
TauCl inhibited the migration of NF-κB into the nucleus. To visualize the translocation of nuclear factor-κB (NF-κB), synovial cells (4 × 104 cells/well in four-well Lab-Tek chamber slides) were cultured. After serum starvation overnight, the cells were treated with taurine chloramine (TauCl) 30 min before stimulation ...
PMC2206429_F1_16316.jpg
What is the focal point of this photograph?
Randomization of alveoli for measurement of alveolar stability. The percentage change in alveolar area between peak inspiration and end expiration. (a) For each microscopic field analyzed, a vertical line bisecting the field was drawn. (b) Each alveolus that contacted this bisecting line was chosen for analysis of alve...
PMC2206429_F1_16318.jpg
Can you identify the primary element in this image?
Randomization of alveoli for measurement of alveolar stability. The percentage change in alveolar area between peak inspiration and end expiration. (a) For each microscopic field analyzed, a vertical line bisecting the field was drawn. (b) Each alveolus that contacted this bisecting line was chosen for analysis of alve...
PMC2206429_F1_16317.jpg
Describe the main subject of this image.
Randomization of alveoli for measurement of alveolar stability. The percentage change in alveolar area between peak inspiration and end expiration. (a) For each microscopic field analyzed, a vertical line bisecting the field was drawn. (b) Each alveolus that contacted this bisecting line was chosen for analysis of alve...
PMC2206429_F1_16319.jpg
What is the central feature of this picture?
Randomization of alveoli for measurement of alveolar stability. The percentage change in alveolar area between peak inspiration and end expiration. (a) For each microscopic field analyzed, a vertical line bisecting the field was drawn. (b) Each alveolus that contacted this bisecting line was chosen for analysis of alve...
PMC2206711_F1_16321.jpg
What is the main focus of this visual representation?
Image from one of the slices obtained by dynamic computed tomography centered on the palpable axillary node in patient AF with right breast carcinoma. A region of interest (ROI) was manually drawn along the margins of the target node (3). ROIs 1 and 2 were positioned in the axillary artery and vein. They were chosen wi...
PMC2206711_F2_16320.jpg
What's the most prominent thing you notice in this picture?
Map of perfusion of patient in Figure 1. The colored scale perfusion map designed using software shows how the perfusion of the target node is similar to that of the muscle. At post-surgical pathology, no metastases were found in the node.
PMC2206715_F2_16328.jpg
What's the most prominent thing you notice in this picture?
Representative histopathologies of three different types of mammary tumors arising in WapInt6sh multiparous females. The top panel shows an undifferentiated tumor; the middle panel shows the features of a papillary adenocarcinoma, including fibrovascular stalks covered in neoplastic epithelium; the bottom panel is more...
PMC2206715_F2_16326.jpg
What is being portrayed in this visual content?
Representative histopathologies of three different types of mammary tumors arising in WapInt6sh multiparous females. The top panel shows an undifferentiated tumor; the middle panel shows the features of a papillary adenocarcinoma, including fibrovascular stalks covered in neoplastic epithelium; the bottom panel is more...
PMC2206715_F2_16327.jpg
Can you identify the primary element in this image?
Representative histopathologies of three different types of mammary tumors arising in WapInt6sh multiparous females. The top panel shows an undifferentiated tumor; the middle panel shows the features of a papillary adenocarcinoma, including fibrovascular stalks covered in neoplastic epithelium; the bottom panel is more...
PMC2206715_F3_16323.jpg
What key item or scene is captured in this photo?
Mammary glands from multiparous WapInt6sh transgenic females show persistent alveolar hyperplasia. (a) Multiple focal alveolar hyperplasias (green arrows) are visible in this carmine alum stained whole mounted mammary gland from a multiparous WapInt6sh transgenic female. LN, lymph node. Magnification 10 ×. (b) A no. 4 ...
PMC2206715_F3_16324.jpg
Can you identify the primary element in this image?
Mammary glands from multiparous WapInt6sh transgenic females show persistent alveolar hyperplasia. (a) Multiple focal alveolar hyperplasias (green arrows) are visible in this carmine alum stained whole mounted mammary gland from a multiparous WapInt6sh transgenic female. LN, lymph node. Magnification 10 ×. (b) A no. 4 ...
PMC2206715_F3_16322.jpg
What key item or scene is captured in this photo?
Mammary glands from multiparous WapInt6sh transgenic females show persistent alveolar hyperplasia. (a) Multiple focal alveolar hyperplasias (green arrows) are visible in this carmine alum stained whole mounted mammary gland from a multiparous WapInt6sh transgenic female. LN, lymph node. Magnification 10 ×. (b) A no. 4 ...
PMC2206723_F7_16331.jpg
Describe the main subject of this image.
Lumbar vertebral histology. Decalcified lumbar vertebrae section stained with human EGFR antibody and anti-versican G3 domain antibody 4B6 of a rat inoculated with (a, b) G3-transfected MT-1 cells when compared to lesser tumor burden observed in a representative control animal (c).
PMC2206723_F7_16329.jpg
What object or scene is depicted here?
Lumbar vertebral histology. Decalcified lumbar vertebrae section stained with human EGFR antibody and anti-versican G3 domain antibody 4B6 of a rat inoculated with (a, b) G3-transfected MT-1 cells when compared to lesser tumor burden observed in a representative control animal (c).
PMC2211299_F7_16332.jpg
What can you see in this picture?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16340.jpg
What object or scene is depicted here?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16335.jpg
What does this image primarily show?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16336.jpg
What is shown in this image?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16334.jpg
What can you see in this picture?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16338.jpg
What is the central feature of this picture?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16339.jpg
What is the main focus of this visual representation?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16333.jpg
What is the core subject represented in this visual?
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211299_F7_16337.jpg
Describe the main subject of this image.
Apg-2 depletion inhibits epithelial morphogenesis in 3-D cultures. Control and Apg-2 RNAi cell lines were cultured as in figure 6. After fixation, the samples were labelled with FITC-phalloidin and antibodies against β-catenin (shown in red), the Golgi marker GP73 (shown in blue), and for DNA (shown in white). Panel B ...
PMC2211301_F7_16351.jpg
What is being portrayed in this visual content?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16346.jpg
What is shown in this image?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16352.jpg
What object or scene is depicted here?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16357.jpg
What's the most prominent thing you notice in this picture?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16361.jpg
What is the central feature of this picture?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16350.jpg
What object or scene is depicted here?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16349.jpg
What is the dominant medical problem in this image?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16364.jpg
What is the principal component of this image?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16353.jpg
What is the central feature of this picture?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16359.jpg
Describe the main subject of this image.
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16365.jpg
What object or scene is depicted here?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16358.jpg
What is the core subject represented in this visual?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16355.jpg
What does this image primarily show?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16356.jpg
What object or scene is depicted here?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16347.jpg
What is being portrayed in this visual content?
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211301_F7_16354.jpg
Describe the main subject of this image.
Filamin and mutated filamin localise to the same actin rich areas. Vegetative amoebae were viewed under a fluorescence microscope. For all but the last row, the first column contains phase contrast images, the second column contains the corresponding fields detecting green immunofluorescence using Alexa Fluor 488-conju...
PMC2211302_F3_16342.jpg
What can you see in this picture?
PET/CT showing extensive hypermetabolic mediastinal adenopathy.
PMC2211302_F4_16345.jpg
What object or scene is depicted here?
Reed-Sternberg cell variants surrounded by small lymphocytes hematoxylin-eosin stain, original magnification ×40.
PMC2211302_F5_16343.jpg
What is the main focus of this visual representation?
CD30 positive Reed-Sternberg cell variants, original magnification ×40, consistent with classical Hodgkin's lymphoma.
PMC2211302_F6_16344.jpg
What is the focal point of this photograph?
Multiple non-necrotizing, epithelioid granulomas, hematoxylin-eosin stain, original magnification ×40.
PMC2211303_F2_16368.jpg
What is being portrayed in this visual content?
Computed tomography scans of the abdomen. Adrenal gland metastasis (upper scan) and lower abdominal mass resulting from inflammation around the melanoma in the vermiform appendix 4 months later (lower scan).
PMC2211323_F5_16374.jpg
What's the most prominent thing you notice in this picture?
Tight junction proteins and ERBB2/3 expression in hESCs. BG01 hESCs were disaggregated to single cells using accutase [52] and cultured in defined conditions. (A) ZO1 expression four and (B) seven days after plating, indicating progressive tight junction formation. (C) Occludin expression 5 days after plating. (D) Gene...
PMC2211323_F5_16370.jpg
What object or scene is depicted here?
Tight junction proteins and ERBB2/3 expression in hESCs. BG01 hESCs were disaggregated to single cells using accutase [52] and cultured in defined conditions. (A) ZO1 expression four and (B) seven days after plating, indicating progressive tight junction formation. (C) Occludin expression 5 days after plating. (D) Gene...
PMC2211323_F5_16372.jpg
What is the dominant medical problem in this image?
Tight junction proteins and ERBB2/3 expression in hESCs. BG01 hESCs were disaggregated to single cells using accutase [52] and cultured in defined conditions. (A) ZO1 expression four and (B) seven days after plating, indicating progressive tight junction formation. (C) Occludin expression 5 days after plating. (D) Gene...
PMC2211323_F5_16373.jpg
What stands out most in this visual?
Tight junction proteins and ERBB2/3 expression in hESCs. BG01 hESCs were disaggregated to single cells using accutase [52] and cultured in defined conditions. (A) ZO1 expression four and (B) seven days after plating, indicating progressive tight junction formation. (C) Occludin expression 5 days after plating. (D) Gene...
PMC2211323_F5_16371.jpg
What is the core subject represented in this visual?
Tight junction proteins and ERBB2/3 expression in hESCs. BG01 hESCs were disaggregated to single cells using accutase [52] and cultured in defined conditions. (A) ZO1 expression four and (B) seven days after plating, indicating progressive tight junction formation. (C) Occludin expression 5 days after plating. (D) Gene...
PMC2211403_pone-0001514-g003_16396.jpg
What is the central feature of this picture?
Three-dimensional structure of AprB from A. fulgidus (A) and selected, homology modeling-based AprB models from Allochromatium vinosum (B) and Pelagibacter ubique (C) (as representatives of SOB from Apr lineage-I), Pyrobaculum calidifontis (D) (as representative of crenarchaeal SRP), Desulfotomaculum reducens (E) (as r...
PMC2211403_pone-0001514-g003_16397.jpg
What is shown in this image?
Three-dimensional structure of AprB from A. fulgidus (A) and selected, homology modeling-based AprB models from Allochromatium vinosum (B) and Pelagibacter ubique (C) (as representatives of SOB from Apr lineage-I), Pyrobaculum calidifontis (D) (as representative of crenarchaeal SRP), Desulfotomaculum reducens (E) (as r...
PMC2211403_pone-0001514-g003_16400.jpg
What does this image primarily show?
Three-dimensional structure of AprB from A. fulgidus (A) and selected, homology modeling-based AprB models from Allochromatium vinosum (B) and Pelagibacter ubique (C) (as representatives of SOB from Apr lineage-I), Pyrobaculum calidifontis (D) (as representative of crenarchaeal SRP), Desulfotomaculum reducens (E) (as r...
PMC2211403_pone-0001514-g003_16401.jpg
What is shown in this image?
Three-dimensional structure of AprB from A. fulgidus (A) and selected, homology modeling-based AprB models from Allochromatium vinosum (B) and Pelagibacter ubique (C) (as representatives of SOB from Apr lineage-I), Pyrobaculum calidifontis (D) (as representative of crenarchaeal SRP), Desulfotomaculum reducens (E) (as r...
PMC2211403_pone-0001514-g005_16385.jpg
What is the focal point of this photograph?
AprB protein matrix surrounding the [4Fe-4S] cluster I and II (residues in a distance of less than 5.0 Å are shown) in the three-dimensional structure from A. fulgidus (A) and selected, homology modeling-based models from Allochromatium vinosum (B), Pelagibacter ubique (C), Pyrobaculum calidifontis (D), Desulfotomaculu...
PMC2211403_pone-0001514-g008_16391.jpg
What object or scene is depicted here?
AprA protein matrix surrounding the FAD cofactor (residues in a distance of less than 4.1 Å are shown) in the three-dimensional structure from A. fulgidus (A) and selected, homology modeling-based models from Allochromatium vinosum (B), Pelagibacter ubique (C), Pyrobaculum calidifontis (D), Desulfotomaculum reducens (E...
PMC2211403_pone-0001514-g008_16395.jpg
What does this image primarily show?
AprA protein matrix surrounding the FAD cofactor (residues in a distance of less than 4.1 Å are shown) in the three-dimensional structure from A. fulgidus (A) and selected, homology modeling-based models from Allochromatium vinosum (B), Pelagibacter ubique (C), Pyrobaculum calidifontis (D), Desulfotomaculum reducens (E...
PMC2211403_pone-0001514-g008_16394.jpg
What is the central feature of this picture?
AprA protein matrix surrounding the FAD cofactor (residues in a distance of less than 4.1 Å are shown) in the three-dimensional structure from A. fulgidus (A) and selected, homology modeling-based models from Allochromatium vinosum (B), Pelagibacter ubique (C), Pyrobaculum calidifontis (D), Desulfotomaculum reducens (E...
PMC2211403_pone-0001514-g008_16390.jpg
Describe the main subject of this image.
AprA protein matrix surrounding the FAD cofactor (residues in a distance of less than 4.1 Å are shown) in the three-dimensional structure from A. fulgidus (A) and selected, homology modeling-based models from Allochromatium vinosum (B), Pelagibacter ubique (C), Pyrobaculum calidifontis (D), Desulfotomaculum reducens (E...
PMC2211483_F7_16411.jpg
What is the focal point of this photograph?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211483_F7_16406.jpg
What is the main focus of this visual representation?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211483_F7_16410.jpg
What is the dominant medical problem in this image?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211483_F7_16409.jpg
What object or scene is depicted here?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211483_F7_16405.jpg
What stands out most in this visual?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211483_F7_16407.jpg
What's the most prominent thing you notice in this picture?
Details of a feather. (A-E) Details of the barn owl's feather p10. (A) Serrations at the outer vane's leading edge. (B) Fringes at the inner vane's trailing edge. (C) Velvet-like dorsal surface of the inner vane. (F-J) Details of the pigeon's feather p10. (F) Leading edge of the outer vane. (G) Trailing edge of the inn...
PMC2211492_F1_16421.jpg
What is being portrayed in this visual content?
Case 1. (A) Generalized conjunctival injection, chemosis and a prominent lesion with elevated, polygonal, hyperemic mounds and small hemorrhages are seen in the superior bulbar conjunctiva. (B) A dense infiltration of cells and several foci of necrosis are present, as is hemorrhage into the conjunctival parenchyma. The...
PMC2211492_F1_16418.jpg
What is the principal component of this image?
Case 1. (A) Generalized conjunctival injection, chemosis and a prominent lesion with elevated, polygonal, hyperemic mounds and small hemorrhages are seen in the superior bulbar conjunctiva. (B) A dense infiltration of cells and several foci of necrosis are present, as is hemorrhage into the conjunctival parenchyma. The...
PMC2211492_F1_16419.jpg
What does this image primarily show?
Case 1. (A) Generalized conjunctival injection, chemosis and a prominent lesion with elevated, polygonal, hyperemic mounds and small hemorrhages are seen in the superior bulbar conjunctiva. (B) A dense infiltration of cells and several foci of necrosis are present, as is hemorrhage into the conjunctival parenchyma. The...
PMC2211492_F2_16416.jpg
What is the central feature of this picture?
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211492_F2_16417.jpg
What is the focal point of this photograph?
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211492_F2_16413.jpg
Can you identify the primary element in this image?
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211492_F2_16414.jpg
What does this image primarily show?
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211492_F2_16415.jpg
Describe the main subject of this image.
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211492_F2_16412.jpg
What is the focal point of this photograph?
Case 2. (A and B) Choroidal vessels are filled with atypical cells (arrows), which are CD68+. (C) A subretinal infiltrate of leukemic cells (arrows), admixed with hemorrhage, is also seen. (D) The subretinal infiltrate and choroidal vessels contain a significant number of CD68+ cells (arrows). R = retina, Ch = choroid....
PMC2211502_F2_16424.jpg
Describe the main subject of this image.
Chemical and physical fixation of the lung. Alveolar epithelial type II cells were studied by cTEM either after chemical (A and B) or after physical (C and D) fixation. The overview in A shows a well-preserved type II cell from a newborn rat lung fixed by instillation of 1.5% GA, 1.5% PFA in Hepes buffer and processed ...
PMC2211502_F2_16426.jpg
Can you identify the primary element in this image?
Chemical and physical fixation of the lung. Alveolar epithelial type II cells were studied by cTEM either after chemical (A and B) or after physical (C and D) fixation. The overview in A shows a well-preserved type II cell from a newborn rat lung fixed by instillation of 1.5% GA, 1.5% PFA in Hepes buffer and processed ...
PMC2211502_F2_16427.jpg
What is the central feature of this picture?
Chemical and physical fixation of the lung. Alveolar epithelial type II cells were studied by cTEM either after chemical (A and B) or after physical (C and D) fixation. The overview in A shows a well-preserved type II cell from a newborn rat lung fixed by instillation of 1.5% GA, 1.5% PFA in Hepes buffer and processed ...
PMC2211502_F3_16423.jpg
What can you see in this picture?
Conventional TEM of polystyrene nanoparticles. This figure demonstrates the impossibility to distinguish between NP and cellular structures by conventional TEM unambiguously. In A, five polystyrene NP (NP!) with a mean diameter of 78 nm are observed next to an A549 cell. Once taken up by the cells, they may have an app...
PMC2211502_F3_16422.jpg
What is the core subject represented in this visual?
Conventional TEM of polystyrene nanoparticles. This figure demonstrates the impossibility to distinguish between NP and cellular structures by conventional TEM unambiguously. In A, five polystyrene NP (NP!) with a mean diameter of 78 nm are observed next to an A549 cell. Once taken up by the cells, they may have an app...
PMC2211502_F5_16428.jpg
What stands out most in this visual?
Titanium detection by ESI and pEELS. A and B show an energy loss imaging (ESI) series of the L3 orbital of Ti at 440 eV (background) and 464 eV (signal) in an erythrocyte culture. In C, the resulting difference is calculated, revealing the distribution of Ti in the sample. Not shown, but used in the three-window calcul...
PMC2211502_F5_16432.jpg
What is the focal point of this photograph?
Titanium detection by ESI and pEELS. A and B show an energy loss imaging (ESI) series of the L3 orbital of Ti at 440 eV (background) and 464 eV (signal) in an erythrocyte culture. In C, the resulting difference is calculated, revealing the distribution of Ti in the sample. Not shown, but used in the three-window calcul...