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PMC2229861_pbio-0050317-g009_17269.jpg | What object or scene is depicted here? | Targeting of mDia2 to the Leading Edge(A) GFP-FH1FH2-mDia2 in B16F1 cells is not efficiently targeted to the membrane and weakly induces filopodia. GFP fluorescence (top) and F-actin (middle) are enriched throughout the cell. Boxed region is enlarged at right. Contrast enhancement shows some FH1FH2-mDia2 at the tips of... |
PMC2229861_pbio-0050317-g009_17268.jpg | What stands out most in this visual? | Targeting of mDia2 to the Leading Edge(A) GFP-FH1FH2-mDia2 in B16F1 cells is not efficiently targeted to the membrane and weakly induces filopodia. GFP fluorescence (top) and F-actin (middle) are enriched throughout the cell. Boxed region is enlarged at right. Contrast enhancement shows some FH1FH2-mDia2 at the tips of... |
PMC2229861_pbio-0050317-g009_17264.jpg | What is the main focus of this visual representation? | Targeting of mDia2 to the Leading Edge(A) GFP-FH1FH2-mDia2 in B16F1 cells is not efficiently targeted to the membrane and weakly induces filopodia. GFP fluorescence (top) and F-actin (middle) are enriched throughout the cell. Boxed region is enlarged at right. Contrast enhancement shows some FH1FH2-mDia2 at the tips of... |
PMC2229861_pbio-0050317-g009_17263.jpg | What's the most prominent thing you notice in this picture? | Targeting of mDia2 to the Leading Edge(A) GFP-FH1FH2-mDia2 in B16F1 cells is not efficiently targeted to the membrane and weakly induces filopodia. GFP fluorescence (top) and F-actin (middle) are enriched throughout the cell. Boxed region is enlarged at right. Contrast enhancement shows some FH1FH2-mDia2 at the tips of... |
PMC2229861_pbio-0050317-g009_17262.jpg | What is the core subject represented in this visual? | Targeting of mDia2 to the Leading Edge(A) GFP-FH1FH2-mDia2 in B16F1 cells is not efficiently targeted to the membrane and weakly induces filopodia. GFP fluorescence (top) and F-actin (middle) are enriched throughout the cell. Boxed region is enlarged at right. Contrast enhancement shows some FH1FH2-mDia2 at the tips of... |
PMC2229861_pbio-0050317-g012_17283.jpg | What is being portrayed in this visual content? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17293.jpg | What is the core subject represented in this visual? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17291.jpg | Can you identify the primary element in this image? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17287.jpg | What is the dominant medical problem in this image? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17290.jpg | Can you identify the primary element in this image? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17288.jpg | What's the most prominent thing you notice in this picture? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17289.jpg | What object or scene is depicted here? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2229861_pbio-0050317-g012_17294.jpg | What object or scene is depicted here? | Phenotype of ΔGBD-mDia2 Expression in Abi1KD Cells(A) GFP-ΔGBD-mDia2 in Abi1KD cells (top row) is not efficiently targeted to the membrane and weakly induces filopodia, as compared to control HeLa cells (bottom row). GFP is shown in the left column and phase contrast overlaid with GFP in red in the middle column. Filop... |
PMC2230681_pcbi-0030253-g008_17307.jpg | What does this image primarily show? | Phase-Contrast Image of the Cell Distribution at the Edge of a Young A−S+ Swarm That Is Expanding to the RightOlder A−S+ swarms stop expanding when their edge becomes smooth and many layers deep. The white scale bar is 50 μm long. |
PMC2231341_F1_17308.jpg | What does this image primarily show? | Images of computed tomography (CT) without contrast. A. Lesion at the base of tongue (indicated by an arrow); B. Conglomerate mass invading the right sternocleidomastoid muscle (indicated by an arrow). |
PMC2231341_F1_17309.jpg | What object or scene is depicted here? | Images of computed tomography (CT) without contrast. A. Lesion at the base of tongue (indicated by an arrow); B. Conglomerate mass invading the right sternocleidomastoid muscle (indicated by an arrow). |
PMC2231341_F2_17310.jpg | Can you identify the primary element in this image? | Microphotographs of the monomorphic PTLD. A. Large lymphoid cells with abundant cytoplasm, vesicular nuclei and prominent nucleoli (H&E, 400× magnification); B. Neoplastic cells positive for CD20 (immunoperoxidase stain, 400× magnification); C. Neoplastic cells positive for EBV LMP (immunoperoxidase stain, 400× magnifi... |
PMC2231341_F2_17311.jpg | What object or scene is depicted here? | Microphotographs of the monomorphic PTLD. A. Large lymphoid cells with abundant cytoplasm, vesicular nuclei and prominent nucleoli (H&E, 400× magnification); B. Neoplastic cells positive for CD20 (immunoperoxidase stain, 400× magnification); C. Neoplastic cells positive for EBV LMP (immunoperoxidase stain, 400× magnifi... |
PMC2231341_F2_17312.jpg | Can you identify the primary element in this image? | Microphotographs of the monomorphic PTLD. A. Large lymphoid cells with abundant cytoplasm, vesicular nuclei and prominent nucleoli (H&E, 400× magnification); B. Neoplastic cells positive for CD20 (immunoperoxidase stain, 400× magnification); C. Neoplastic cells positive for EBV LMP (immunoperoxidase stain, 400× magnifi... |
PMC2231377_F2_17314.jpg | What can you see in this picture? | Photograph of surgical technique to minimise 'dog-ears' in mastectomy. Please see text. |
PMC2231377_F2_17313.jpg | What is shown in this image? | Photograph of surgical technique to minimise 'dog-ears' in mastectomy. Please see text. |
PMC2231377_F3_17315.jpg | What is the main focus of this visual representation? | Photograph of surgical technique to minimise 'dog-ears' in mastectomy. Please see text. |
PMC2233634_F1_17316.jpg | What key item or scene is captured in this photo? | GM-CSFR alpha is present on adult neural stem cells. A, B, GM-CSF receptor α is expressed on cells in the subgranular zone of the dentate gyrus, and in cells with extended processes in the granular cell layer that are reminiscent of migrating neural stem cells (A, 10× original magnification; B, 40× original magnificati... |
PMC2233634_F1_17317.jpg | What is the central feature of this picture? | GM-CSFR alpha is present on adult neural stem cells. A, B, GM-CSF receptor α is expressed on cells in the subgranular zone of the dentate gyrus, and in cells with extended processes in the granular cell layer that are reminiscent of migrating neural stem cells (A, 10× original magnification; B, 40× original magnificati... |
PMC2233634_F1_17321.jpg | What is the main focus of this visual representation? | GM-CSFR alpha is present on adult neural stem cells. A, B, GM-CSF receptor α is expressed on cells in the subgranular zone of the dentate gyrus, and in cells with extended processes in the granular cell layer that are reminiscent of migrating neural stem cells (A, 10× original magnification; B, 40× original magnificati... |
PMC2233636_F1_17323.jpg | What is the core subject represented in this visual? | Histopathological aspects of benign and malignant mixed tumours of human salivary and canine mammary glands by haematoxylin and eosin (HE) stain; original magnification, 10×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary gland; (C) Carcinoma ex-pleomorphic adenoma in human salivary... |
PMC2233636_F1_17322.jpg | What is the principal component of this image? | Histopathological aspects of benign and malignant mixed tumours of human salivary and canine mammary glands by haematoxylin and eosin (HE) stain; original magnification, 10×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary gland; (C) Carcinoma ex-pleomorphic adenoma in human salivary... |
PMC2233636_F1_17324.jpg | What object or scene is depicted here? | Histopathological aspects of benign and malignant mixed tumours of human salivary and canine mammary glands by haematoxylin and eosin (HE) stain; original magnification, 10×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary gland; (C) Carcinoma ex-pleomorphic adenoma in human salivary... |
PMC2233636_F1_17325.jpg | What is the main focus of this visual representation? | Histopathological aspects of benign and malignant mixed tumours of human salivary and canine mammary glands by haematoxylin and eosin (HE) stain; original magnification, 10×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary gland; (C) Carcinoma ex-pleomorphic adenoma in human salivary... |
PMC2233636_F2_17330.jpg | Describe the main subject of this image. | Immunohistochemical aspects of p63 antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary tumour; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland; (D) Metaplastic carcinoma in canine mammary gland. Note myoepithelial p63-negative cell... |
PMC2233636_F2_17333.jpg | What is the focal point of this photograph? | Immunohistochemical aspects of p63 antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary tumour; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland; (D) Metaplastic carcinoma in canine mammary gland. Note myoepithelial p63-negative cell... |
PMC2233636_F2_17331.jpg | What is the core subject represented in this visual? | Immunohistochemical aspects of p63 antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary tumour; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland; (D) Metaplastic carcinoma in canine mammary gland. Note myoepithelial p63-negative cell... |
PMC2233636_F2_17332.jpg | What is being portrayed in this visual content? | Immunohistochemical aspects of p63 antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland; (B) Mixed tumour in canine mammary tumour; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland; (D) Metaplastic carcinoma in canine mammary gland. Note myoepithelial p63-negative cell... |
PMC2233636_F3_17336.jpg | What is the dominant medical problem in this image? | Immunohistochemical aspects of β-catenin antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland with membrane and cytoplasmic β-catenin stain; (B) Mixed tumour in canine mammary tumour with membrane and cytoplasmic β-catenin stain; (C) Carcinoma ex-pleomorphic adenoma in human saliv... |
PMC2233636_F3_17337.jpg | What is shown in this image? | Immunohistochemical aspects of β-catenin antigen stain; original magnification, 40×. (A) Pleomorphic adenoma in human salivary gland with membrane and cytoplasmic β-catenin stain; (B) Mixed tumour in canine mammary tumour with membrane and cytoplasmic β-catenin stain; (C) Carcinoma ex-pleomorphic adenoma in human saliv... |
PMC2233636_F4_17327.jpg | What is the principal component of this image? | Immunohistochemical aspects of E-cadherin membrane antigen stain; original magnification, 40×.(A) Pleomorphic adenoma in human salivary gland with membrane E-cadherin stain; (B) Mixed tumour in canine mammary gland with membrane E-cadherin stain; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland with evident... |
PMC2233636_F4_17328.jpg | What is being portrayed in this visual content? | Immunohistochemical aspects of E-cadherin membrane antigen stain; original magnification, 40×.(A) Pleomorphic adenoma in human salivary gland with membrane E-cadherin stain; (B) Mixed tumour in canine mammary gland with membrane E-cadherin stain; (C) Carcinoma ex-pleomorphic adenoma in human salivary gland with evident... |
PMC2233640_F6_17339.jpg | What is the central feature of this picture? | Human NCU-G1 co-localises with PPAR-alpha in the nucleus. HeLa cells were transiently transfected with 0.8 μg pNCU-G1-EGFP and 0.8 μg pRFP-PPAR-alpha. Twenty hours after transfection WY14643 was added to 2 μM. Six hours later the live cells were analysed by confocal fluorescence microscopy. Panel A: Green fluorescence ... |
PMC2233640_F6_17338.jpg | What is the core subject represented in this visual? | Human NCU-G1 co-localises with PPAR-alpha in the nucleus. HeLa cells were transiently transfected with 0.8 μg pNCU-G1-EGFP and 0.8 μg pRFP-PPAR-alpha. Twenty hours after transfection WY14643 was added to 2 μM. Six hours later the live cells were analysed by confocal fluorescence microscopy. Panel A: Green fluorescence ... |
PMC2233674_ppat-0040026-g005_17341.jpg | What stands out most in this visual? | Cytotoxic Activity of Supernatants from EHE-NE18, EHE-NE18ΔnetB1, and Complemented MutantsThe LMH cells were cultured until 70% confluence in 24 well plates coated in 0.2% gelatine and grown in EMEM medium at 37 °C.(A) Cytotoxicity assays. Culture supernatant was added to the medium and incubated for up to 16 h at 37 °... |
PMC2233674_ppat-0040026-g005_17349.jpg | What stands out most in this visual? | Cytotoxic Activity of Supernatants from EHE-NE18, EHE-NE18ΔnetB1, and Complemented MutantsThe LMH cells were cultured until 70% confluence in 24 well plates coated in 0.2% gelatine and grown in EMEM medium at 37 °C.(A) Cytotoxicity assays. Culture supernatant was added to the medium and incubated for up to 16 h at 37 °... |
PMC2233674_ppat-0040026-g005_17347.jpg | What is the dominant medical problem in this image? | Cytotoxic Activity of Supernatants from EHE-NE18, EHE-NE18ΔnetB1, and Complemented MutantsThe LMH cells were cultured until 70% confluence in 24 well plates coated in 0.2% gelatine and grown in EMEM medium at 37 °C.(A) Cytotoxicity assays. Culture supernatant was added to the medium and incubated for up to 16 h at 37 °... |
PMC2233674_ppat-0040026-g005_17344.jpg | What is shown in this image? | Cytotoxic Activity of Supernatants from EHE-NE18, EHE-NE18ΔnetB1, and Complemented MutantsThe LMH cells were cultured until 70% confluence in 24 well plates coated in 0.2% gelatine and grown in EMEM medium at 37 °C.(A) Cytotoxicity assays. Culture supernatant was added to the medium and incubated for up to 16 h at 37 °... |
PMC2233741_fig7_17352.jpg | Can you identify the primary element in this image? | Induction of the triglyceride
hydrolysis pathway by Wy14643 is paralleled by a decrease in hepatic lipid stores. Hematoxilin and eosin staining (a) and oil red O staining (b) of representative liver sections of wild-type and PPARα-null mice treated or not with Wy14643 for 7
days (magnification 200X). All mice were give... |
PMC2233741_fig7_17350.jpg | What can you see in this picture? | Induction of the triglyceride
hydrolysis pathway by Wy14643 is paralleled by a decrease in hepatic lipid stores. Hematoxilin and eosin staining (a) and oil red O staining (b) of representative liver sections of wild-type and PPARα-null mice treated or not with Wy14643 for 7
days (magnification 200X). All mice were give... |
PMC2233741_fig7_17351.jpg | Can you identify the primary element in this image? | Induction of the triglyceride
hydrolysis pathway by Wy14643 is paralleled by a decrease in hepatic lipid stores. Hematoxilin and eosin staining (a) and oil red O staining (b) of representative liver sections of wild-type and PPARα-null mice treated or not with Wy14643 for 7
days (magnification 200X). All mice were give... |
PMC2233807_fig4_17358.jpg | What key item or scene is captured in this photo? | (a) Single subject statistical maps (left) and
BOLD time-courses (right) of the right anterior insula in the first (upper) and
in the last sessions (lower). The selected region of interest is delineated by
the green box. The time course of the BOLD activity (white line) is related to
the ROI selected and is showing the... |
PMC2233807_fig4_17360.jpg | What key item or scene is captured in this photo? | (a) Single subject statistical maps (left) and
BOLD time-courses (right) of the right anterior insula in the first (upper) and
in the last sessions (lower). The selected region of interest is delineated by
the green box. The time course of the BOLD activity (white line) is related to
the ROI selected and is showing the... |
PMC2233807_fig4_17354.jpg | What does this image primarily show? | (a) Single subject statistical maps (left) and
BOLD time-courses (right) of the right anterior insula in the first (upper) and
in the last sessions (lower). The selected region of interest is delineated by
the green box. The time course of the BOLD activity (white line) is related to
the ROI selected and is showing the... |
PMC2233807_fig4_17356.jpg | What stands out most in this visual? | (a) Single subject statistical maps (left) and
BOLD time-courses (right) of the right anterior insula in the first (upper) and
in the last sessions (lower). The selected region of interest is delineated by
the green box. The time course of the BOLD activity (white line) is related to
the ROI selected and is showing the... |
PMC2233807_fig4_17355.jpg | What is the main focus of this visual representation? | (a) Single subject statistical maps (left) and
BOLD time-courses (right) of the right anterior insula in the first (upper) and
in the last sessions (lower). The selected region of interest is delineated by
the green box. The time course of the BOLD activity (white line) is related to
the ROI selected and is showing the... |
PMC2233876_fig3_17362.jpg | What is the main focus of this visual representation? | (a), (b), and (c) were from the same patient. The pathological diagnosis is right upper pulmonary squamous carcinoma. There were typical manifestations on CT, PET, and
integrated PET/CT. The mass on CT is 2.4 cm×2.5 cm. The SUVmax of early PET imaging is 7.8. |
PMC2233876_fig3_17361.jpg | What does this image primarily show? | (a), (b), and (c) were from the same patient. The pathological diagnosis is right upper pulmonary squamous carcinoma. There were typical manifestations on CT, PET, and
integrated PET/CT. The mass on CT is 2.4 cm×2.5 cm. The SUVmax of early PET imaging is 7.8. |
PMC2233876_fig3_17363.jpg | What is the main focus of this visual representation? | (a), (b), and (c) were from the same patient. The pathological diagnosis is right upper pulmonary squamous carcinoma. There were typical manifestations on CT, PET, and
integrated PET/CT. The mass on CT is 2.4 cm×2.5 cm. The SUVmax of early PET imaging is 7.8. |
PMC2233876_fig4_17366.jpg | Describe the main subject of this image. | (a), (b), and (c) were from the same patient. The
pathological diagnosis is left upper lung adenocarcinoma. On CT, a small module
(0.9 cm×1.0 cm) with lobulation and speculated margin was seen in
the left upper lung (a). No typical manifestation was seen on PET. The SUVmax
of early PET imaging was 1.9 (b). Integrated P... |
PMC2233876_fig4_17364.jpg | What can you see in this picture? | (a), (b), and (c) were from the same patient. The
pathological diagnosis is left upper lung adenocarcinoma. On CT, a small module
(0.9 cm×1.0 cm) with lobulation and speculated margin was seen in
the left upper lung (a). No typical manifestation was seen on PET. The SUVmax
of early PET imaging was 1.9 (b). Integrated P... |
PMC2233876_fig4_17365.jpg | What object or scene is depicted here? | (a), (b), and (c) were from the same patient. The
pathological diagnosis is left upper lung adenocarcinoma. On CT, a small module
(0.9 cm×1.0 cm) with lobulation and speculated margin was seen in
the left upper lung (a). No typical manifestation was seen on PET. The SUVmax
of early PET imaging was 1.9 (b). Integrated P... |
PMC2233876_fig5_17367.jpg | What does this image primarily show? | (a), (b), and (c) were from the same patient. The pathology
is left lung inflammation. A big mass (5.3 cm×5.7 cm) with lobulation and spurring was seen on CT (a). Malignant tumor was suspected on CT. False positivity was seen on PET;
its early imaging SUVmax is 6.6 (b). The integrated PET/CT also suggested
possible lun... |
PMC2233876_fig5_17369.jpg | What can you see in this picture? | (a), (b), and (c) were from the same patient. The pathology
is left lung inflammation. A big mass (5.3 cm×5.7 cm) with lobulation and spurring was seen on CT (a). Malignant tumor was suspected on CT. False positivity was seen on PET;
its early imaging SUVmax is 6.6 (b). The integrated PET/CT also suggested
possible lun... |
PMC2233876_fig5_17368.jpg | What is being portrayed in this visual content? | (a), (b), and (c) were from the same patient. The pathology
is left lung inflammation. A big mass (5.3 cm×5.7 cm) with lobulation and spurring was seen on CT (a). Malignant tumor was suspected on CT. False positivity was seen on PET;
its early imaging SUVmax is 6.6 (b). The integrated PET/CT also suggested
possible lun... |
PMC2233985_fig1_17370.jpg | What can you see in this picture? |
Seedmask and exclusion mask. Atlas was warped to a high-resolution, high-signal-to-noise ratio template.
The pulvinar was extracted from the atlas and the atlas-to-subject transformation estimated for each subject was applied to the mask of the pulvinar to fit it properly to each subject. An example of the obtained ri... |
PMC2233985_fig1_17371.jpg | Describe the main subject of this image. |
Seedmask and exclusion mask. Atlas was warped to a high-resolution, high-signal-to-noise ratio template.
The pulvinar was extracted from the atlas and the atlas-to-subject transformation estimated for each subject was applied to the mask of the pulvinar to fit it properly to each subject. An example of the obtained ri... |
PMC2233985_fig2_17382.jpg | What object or scene is depicted here? |
Population probability maps of reconstructed pulvinar tracts based on tractography in six
healthy subjects. Fiber tracking was initiated from a seed mask in the
right pulvinar demonstrated in red hues and from a seed mask in the left
pulvinar demonstrated in blue hues. Intensity of the color
scales represents the prop... |
PMC2233986_fig2_17378.jpg | What is the principal component of this image? | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2233986_fig2_17376.jpg | What is the focal point of this photograph? | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2233986_fig2_17380.jpg | What object or scene is depicted here? | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2233986_fig2_17372.jpg | What object or scene is depicted here? | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2233986_fig2_17377.jpg | Describe the main subject of this image. | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2233986_fig2_17373.jpg | Can you identify the primary element in this image? | Reconstruction results for the ring of spheres phantom.
(a) The ring of spheres phantom;
(b) EM reconstruction of ideal projection data;
(c) the same ring of spheres phantom with Poisson distribution with total
counts of 106; (d) EM reconstruction with no PSF correction from blurry
projection data of (a);
(e) bli... |
PMC2234355_fig1_17384.jpg | What does this image primarily show? | Thalamus segmentation. (a) The initial thalamus segmentation is conducted interactively, that is, the user need to identify the pair of symmetric clusters (left thalamus and right thalamus, marked by circles in the figure for illustration) from other clusters. Since the thalamus is bounded by relatively homogenous stru... |
PMC2234355_fig1_17383.jpg | Can you identify the primary element in this image? | Thalamus segmentation. (a) The initial thalamus segmentation is conducted interactively, that is, the user need to identify the pair of symmetric clusters (left thalamus and right thalamus, marked by circles in the figure for illustration) from other clusters. Since the thalamus is bounded by relatively homogenous stru... |
PMC2234406_F2_17386.jpg | Describe the main subject of this image. | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17390.jpg | What key item or scene is captured in this photo? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17388.jpg | What is being portrayed in this visual content? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17401.jpg | What object or scene is depicted here? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17402.jpg | What is being portrayed in this visual content? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17396.jpg | What is the central feature of this picture? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17410.jpg | What is the core subject represented in this visual? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17408.jpg | Describe the main subject of this image. | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234406_F2_17389.jpg | What object or scene is depicted here? | Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit... |
PMC2234418_F1_17414.jpg | What is the main focus of this visual representation? | The three planning cases selected for the study. (A) base of tongue, (B) mandible, (C) left thoracic wal. An axial CT slice approximately at the centre of the target volume is shown together with a reconstructed coronal or sagittal view; target volumes are shown as overlays. |
PMC2234418_F3_17415.jpg | What is the dominant medical problem in this image? | Examples of isodose distributions (Head and Neck case) for the two extreme smoothing conditions s25 (left) and s80 (right). Isodose lines are normalised to the dose prescribed to the smaller volume receiving the higher prescribed dose. The 73% isodose refers to the 90% of the dose prescribed to the large volume. |
PMC2234418_F3_17418.jpg | What is shown in this image? | Examples of isodose distributions (Head and Neck case) for the two extreme smoothing conditions s25 (left) and s80 (right). Isodose lines are normalised to the dose prescribed to the smaller volume receiving the higher prescribed dose. The 73% isodose refers to the 90% of the dose prescribed to the large volume. |
PMC2234427_F5_17421.jpg | What is the core subject represented in this visual? | Immunohistochemical staining for α-smooth muscle actin. Immunohistochemical staining for α-smooth muscle actin (ASMA, brown) showing clearly more ASMA-positive cells in the matrigel plugs of mice carrying the activated PDGFR-beta (B), compared wild type mice (A) (the same magnification was used in Fig.5A and Fig.5B). |
PMC2234427_F5_17420.jpg | What is the focal point of this photograph? | Immunohistochemical staining for α-smooth muscle actin. Immunohistochemical staining for α-smooth muscle actin (ASMA, brown) showing clearly more ASMA-positive cells in the matrigel plugs of mice carrying the activated PDGFR-beta (B), compared wild type mice (A) (the same magnification was used in Fig.5A and Fig.5B). |
PMC2234431_F1_17422.jpg | What object or scene is depicted here? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17428.jpg | Can you identify the primary element in this image? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17429.jpg | Describe the main subject of this image. | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17431.jpg | Describe the main subject of this image. | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17432.jpg | What is being portrayed in this visual content? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17423.jpg | What stands out most in this visual? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17427.jpg | What's the most prominent thing you notice in this picture? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17430.jpg | What can you see in this picture? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17425.jpg | What is the main focus of this visual representation? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F1_17424.jpg | What does this image primarily show? | Effect of ubiquitination on subcellular localization of Tax. Tax localization alone (A-F, top row) or together with DAPI to visualize the nucleus (A-F, bottom row) was examined by immunofluorescent microscopy in transfected 293 cells. Tax is expressed in nuclear foci in the absence of DNA damage (A) and is localized in... |
PMC2234431_F5_17440.jpg | What is the central feature of this picture? | Mutation of lysine residues 280 and 284 prevents UV-induced dissociation of Tax from TSS. Wild-type (A and B), M33 (C and D), K6R (E and F), K7R (G and H), or K8R (I and J) Tax was transiently expressed in 293 cells for 48 hrs and subjected to 30 J/m2 UV irradiation (B, D, F, H, J) or mock irradiated (A, C, E, G, I) an... |
PMC2234431_F5_17441.jpg | What can you see in this picture? | Mutation of lysine residues 280 and 284 prevents UV-induced dissociation of Tax from TSS. Wild-type (A and B), M33 (C and D), K6R (E and F), K7R (G and H), or K8R (I and J) Tax was transiently expressed in 293 cells for 48 hrs and subjected to 30 J/m2 UV irradiation (B, D, F, H, J) or mock irradiated (A, C, E, G, I) an... |
PMC2235833_F1_17442.jpg | What is the focal point of this photograph? | Ewing tumor cells overexpressing EGFR. Cells (EWS TC71 and EWS IOR/CAR) were fixed and stained for EGFR using rabbit polyclonal antibodies, which were visualized with goat Cy3-conjugated secondary antibodies. Images show Cy3 fluorescence (left), DAPI staining of nuclei (middle) and merge (right). Images were recorded b... |
PMC2235833_F1_17446.jpg | What is the central feature of this picture? | Ewing tumor cells overexpressing EGFR. Cells (EWS TC71 and EWS IOR/CAR) were fixed and stained for EGFR using rabbit polyclonal antibodies, which were visualized with goat Cy3-conjugated secondary antibodies. Images show Cy3 fluorescence (left), DAPI staining of nuclei (middle) and merge (right). Images were recorded b... |
PMC2235833_F1_17445.jpg | What is being portrayed in this visual content? | Ewing tumor cells overexpressing EGFR. Cells (EWS TC71 and EWS IOR/CAR) were fixed and stained for EGFR using rabbit polyclonal antibodies, which were visualized with goat Cy3-conjugated secondary antibodies. Images show Cy3 fluorescence (left), DAPI staining of nuclei (middle) and merge (right). Images were recorded b... |
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