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PMC2263064_F1_18596.jpg
What can you see in this picture?
Magnetic resonance tomography shows isolated unilateral distension of the right optic nerve (arrows in panels a and b).
PMC2263076_F2_18601.jpg
Describe the main subject of this image.
Effect of IGF-I gene therapy on lactotropic cells of pituitary adenomas. Representative fields of specifically immunostained PRL-cells in the pituitary gland of an intact (Intact) rat, an animal treated with estrogen for 4 weeks (E only), and animal receiving estrogen for 4 weeks and RAd-GFP during the last experimenta...
PMC2263076_F2_18599.jpg
What key item or scene is captured in this photo?
Effect of IGF-I gene therapy on lactotropic cells of pituitary adenomas. Representative fields of specifically immunostained PRL-cells in the pituitary gland of an intact (Intact) rat, an animal treated with estrogen for 4 weeks (E only), and animal receiving estrogen for 4 weeks and RAd-GFP during the last experimenta...
PMC2263076_F2_18602.jpg
What is being portrayed in this visual content?
Effect of IGF-I gene therapy on lactotropic cells of pituitary adenomas. Representative fields of specifically immunostained PRL-cells in the pituitary gland of an intact (Intact) rat, an animal treated with estrogen for 4 weeks (E only), and animal receiving estrogen for 4 weeks and RAd-GFP during the last experimenta...
PMC2263076_F2_18600.jpg
Describe the main subject of this image.
Effect of IGF-I gene therapy on lactotropic cells of pituitary adenomas. Representative fields of specifically immunostained PRL-cells in the pituitary gland of an intact (Intact) rat, an animal treated with estrogen for 4 weeks (E only), and animal receiving estrogen for 4 weeks and RAd-GFP during the last experimenta...
PMC2265047_f4-ehp0116-000308_18607.jpg
What object or scene is depicted here?
Electron micrographs showing ultrastructure of thyroid from F1 female offspring on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Thyroid section from control animal. The follicular architecture consists of a single layer of t...
PMC2265047_f4-ehp0116-000308_18608.jpg
What is shown in this image?
Electron micrographs showing ultrastructure of thyroid from F1 female offspring on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Thyroid section from control animal. The follicular architecture consists of a single layer of t...
PMC2265047_f4-ehp0116-000308_18610.jpg
What is the principal component of this image?
Electron micrographs showing ultrastructure of thyroid from F1 female offspring on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Thyroid section from control animal. The follicular architecture consists of a single layer of t...
PMC2265047_f5-ehp0116-000308_18603.jpg
What is the principal component of this image?
Electron micrographs showing ultrastructure of ovaries from F1 female offspring in estrus on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Control ovary showing vesicular structures with homogeneously dense granular material ...
PMC2265047_f5-ehp0116-000308_18604.jpg
What does this image primarily show?
Electron micrographs showing ultrastructure of ovaries from F1 female offspring in estrus on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Control ovary showing vesicular structures with homogeneously dense granular material ...
PMC2265047_f5-ehp0116-000308_18605.jpg
What key item or scene is captured in this photo?
Electron micrographs showing ultrastructure of ovaries from F1 female offspring in estrus on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Control ovary showing vesicular structures with homogeneously dense granular material ...
PMC2265047_f5-ehp0116-000308_18606.jpg
What stands out most in this visual?
Electron micrographs showing ultrastructure of ovaries from F1 female offspring in estrus on approximately PND100 after treatment with vehicle or PBDE-47 (140 or 700 μg/kg bw) to F0 dams on GD6. PTU was administered on GD7–PND21. (A) Control ovary showing vesicular structures with homogeneously dense granular material ...
PMC2265270_F12_18612.jpg
What object or scene is depicted here?
Radiograph of Hall PMC on tooth 54 (URD) recorded as unsatisfactory fit. Patient randomisation number 34.
PMC2265287_F5_18615.jpg
What is the core subject represented in this visual?
Blocks of archived lung from autopsies of patients dying without a lung disease showed normal staining for ferritin at the airways and among a few alveolar macrophages (left). Positive staining for ferritin was increased in lung tissue of patients diagnosed with PAP (right). Expression of the protein in the patients wi...
PMC2265288_F8_18619.jpg
What does this image primarily show?
T2 weighted MR images of a representive RAW cells incubated with different volume of MC-IOPs (11.2 mg/ml) for 5 h, (a) longitudinal section, (b) coronal section and (c) signal intensity of sample c to 3 (lane c~3; control, 50, 100 and 200 μl MC-IOPs, respectively).
PMC2265291_F2_18617.jpg
What is shown in this image?
Radiograph following caesarean section, 4 weeks post injury.
PMC2265291_F2_18616.jpg
What is the central feature of this picture?
Radiograph following caesarean section, 4 weeks post injury.
PMC2265291_F3_18623.jpg
What is the focal point of this photograph?
Radiograph 8 weeks and 2 years post injury.
PMC2265291_F3_18622.jpg
What is the core subject represented in this visual?
Radiograph 8 weeks and 2 years post injury.
PMC2265291_F3_18621.jpg
What is shown in this image?
Radiograph 8 weeks and 2 years post injury.
PMC2265412_pgen-1000027-g003_18626.jpg
What is being portrayed in this visual content?
Suppressors of Inclusion Formation Identified by RNAi.(A) Confocal images showing head region of α-synuclein-YFP transgenic animals fed on OP50 bacteria, bacteria containing L4440 (empty vector) and expressing double stranded RNA targeting two representative genes (F26H11.4 and Y48G1A.6) found to increase inclusion for...
PMC2265412_pgen-1000027-g003_18624.jpg
What key item or scene is captured in this photo?
Suppressors of Inclusion Formation Identified by RNAi.(A) Confocal images showing head region of α-synuclein-YFP transgenic animals fed on OP50 bacteria, bacteria containing L4440 (empty vector) and expressing double stranded RNA targeting two representative genes (F26H11.4 and Y48G1A.6) found to increase inclusion for...
PMC2265412_pgen-1000027-g003_18628.jpg
What is the core subject represented in this visual?
Suppressors of Inclusion Formation Identified by RNAi.(A) Confocal images showing head region of α-synuclein-YFP transgenic animals fed on OP50 bacteria, bacteria containing L4440 (empty vector) and expressing double stranded RNA targeting two representative genes (F26H11.4 and Y48G1A.6) found to increase inclusion for...
PMC2265430_ppat-1000026-g001_18629.jpg
What can you see in this picture?
Micrograph of Negative Stained Whole Cell Streptococcus pneumoniae TIGR4.Sample stained with 1% buffered phosphotungstic acid (PTA). Open arrows indicate an individual single pilus; arrow indicates bundles of individual pili. Scale bar, 200 nm. (Philips TEM CM200 FEG microscope at 50000× magnification, working at low-d...
PMC2265430_ppat-1000026-g003_18632.jpg
What stands out most in this visual?
Triple Immunoelectron-Microscopy (IEM) Analysis of the Pilus Subunits of Streptococcus pneumoniae.Isolated pili material (A) was incubated with antisera raised against His-tagged RrgA, RrgB and RrgC and conjugated respectively to 15 nm, 5 nm and 10 nm gold particles. The image shows the pilus backbone stained with gold...
PMC2265430_ppat-1000026-g003_18630.jpg
What's the most prominent thing you notice in this picture?
Triple Immunoelectron-Microscopy (IEM) Analysis of the Pilus Subunits of Streptococcus pneumoniae.Isolated pili material (A) was incubated with antisera raised against His-tagged RrgA, RrgB and RrgC and conjugated respectively to 15 nm, 5 nm and 10 nm gold particles. The image shows the pilus backbone stained with gold...
PMC2265479_pgen-1000009-g004_18649.jpg
Describe the main subject of this image.
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g004_18648.jpg
What is being portrayed in this visual content?
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g004_18646.jpg
What is being portrayed in this visual content?
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g004_18644.jpg
What does this image primarily show?
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g004_18645.jpg
What stands out most in this visual?
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g004_18647.jpg
What does this image primarily show?
Reduced size in hdac3 mutant wing discs is due to ectopic apoptosis.(A) Third instar larval wing imaginal disc from a hdac3+/− heterozygote stained with anti-Armadillo antibody and photographed at the same magnification as the wing disc from a hdac3I/hdac3J mutant larva shown in (B). (C) hdac3+/− leg disc. (D) hdac3I/h...
PMC2265479_pgen-1000009-g005_18635.jpg
What is the dominant medical problem in this image?
Induction of apoptosis in hdac3 mutant wing discs is cell-autonomous and accompanied by hid mRNA induction.(A–D) show in situ hybridizations to track the indicated mRNAs in imaginal discs from hdac3+/− heterozygotes (A and C) versus from hdac3I/hdac3J mutants (B and D). Hybridization probes detect hid mRNA (A and B) or...
PMC2265479_pgen-1000009-g005_18641.jpg
What is the dominant medical problem in this image?
Induction of apoptosis in hdac3 mutant wing discs is cell-autonomous and accompanied by hid mRNA induction.(A–D) show in situ hybridizations to track the indicated mRNAs in imaginal discs from hdac3+/− heterozygotes (A and C) versus from hdac3I/hdac3J mutants (B and D). Hybridization probes detect hid mRNA (A and B) or...
PMC2265479_pgen-1000009-g005_18639.jpg
What object or scene is depicted here?
Induction of apoptosis in hdac3 mutant wing discs is cell-autonomous and accompanied by hid mRNA induction.(A–D) show in situ hybridizations to track the indicated mRNAs in imaginal discs from hdac3+/− heterozygotes (A and C) versus from hdac3I/hdac3J mutants (B and D). Hybridization probes detect hid mRNA (A and B) or...
PMC2265479_pgen-1000009-g005_18638.jpg
What does this image primarily show?
Induction of apoptosis in hdac3 mutant wing discs is cell-autonomous and accompanied by hid mRNA induction.(A–D) show in situ hybridizations to track the indicated mRNAs in imaginal discs from hdac3+/− heterozygotes (A and C) versus from hdac3I/hdac3J mutants (B and D). Hybridization probes detect hid mRNA (A and B) or...
PMC2265479_pgen-1000009-g005_18637.jpg
What stands out most in this visual?
Induction of apoptosis in hdac3 mutant wing discs is cell-autonomous and accompanied by hid mRNA induction.(A–D) show in situ hybridizations to track the indicated mRNAs in imaginal discs from hdac3+/− heterozygotes (A and C) versus from hdac3I/hdac3J mutants (B and D). Hybridization probes detect hid mRNA (A and B) or...
PMC2265479_pgen-1000009-g006_18656.jpg
What's the most prominent thing you notice in this picture?
Analysis of hdac1 mutant wing discs and clones for effects upon apoptosis and proliferation.(A,B) hdac1m3-10 homozygous mutant clones were generated in a field of hdac1+/hdac1m3-10 heterozygous wing disc tissue. (A) Wing disc showing a GFP-negative hdac1m3-10 mutant clone (arrow) and its wild- type twinspot clone marke...
PMC2265479_pgen-1000009-g006_18655.jpg
What is the central feature of this picture?
Analysis of hdac1 mutant wing discs and clones for effects upon apoptosis and proliferation.(A,B) hdac1m3-10 homozygous mutant clones were generated in a field of hdac1+/hdac1m3-10 heterozygous wing disc tissue. (A) Wing disc showing a GFP-negative hdac1m3-10 mutant clone (arrow) and its wild- type twinspot clone marke...
PMC2265479_pgen-1000009-g006_18654.jpg
What is the dominant medical problem in this image?
Analysis of hdac1 mutant wing discs and clones for effects upon apoptosis and proliferation.(A,B) hdac1m3-10 homozygous mutant clones were generated in a field of hdac1+/hdac1m3-10 heterozygous wing disc tissue. (A) Wing disc showing a GFP-negative hdac1m3-10 mutant clone (arrow) and its wild- type twinspot clone marke...
PMC2265479_pgen-1000009-g006_18651.jpg
What stands out most in this visual?
Analysis of hdac1 mutant wing discs and clones for effects upon apoptosis and proliferation.(A,B) hdac1m3-10 homozygous mutant clones were generated in a field of hdac1+/hdac1m3-10 heterozygous wing disc tissue. (A) Wing disc showing a GFP-negative hdac1m3-10 mutant clone (arrow) and its wild- type twinspot clone marke...
PMC2265488_pgen-1000022-g004_18660.jpg
Describe the main subject of this image.
Tomographic Reconstruction of an eat-3(ad426) Mitochondrion.(A,B) Front and rear views of an eat-3 mitochondrion reconstructed by electron tomography. Outer membrane is shown in red. Inner membrane is shown in green. Bubbles on the side of the mitochondrion, which are also shown in green, are matrix compartments separa...
PMC2265488_pgen-1000022-g004_18657.jpg
What object or scene is depicted here?
Tomographic Reconstruction of an eat-3(ad426) Mitochondrion.(A,B) Front and rear views of an eat-3 mitochondrion reconstructed by electron tomography. Outer membrane is shown in red. Inner membrane is shown in green. Bubbles on the side of the mitochondrion, which are also shown in green, are matrix compartments separa...
PMC2265488_pgen-1000022-g004_18659.jpg
Can you identify the primary element in this image?
Tomographic Reconstruction of an eat-3(ad426) Mitochondrion.(A,B) Front and rear views of an eat-3 mitochondrion reconstructed by electron tomography. Outer membrane is shown in red. Inner membrane is shown in green. Bubbles on the side of the mitochondrion, which are also shown in green, are matrix compartments separa...
PMC2265519_pcbi-1000006-g001_18664.jpg
What key item or scene is captured in this photo?
Space-filling representation of the X-Ray structure of the GroEL/GroES/ADP complex [5].Colours represent the type of surface: all hydrophobic amino acids (A, V, L, I, M, F, P, Y) are in yellow, while the polar ones (S, T, H, C, N, Q, K, R, D, E) are red. The sphere in the equatorial region has a radius of 40 Å and mode...
PMC2265531_pgen-1000025-g003_18665.jpg
What is the principal component of this image?
Analysis of hagfish MgRunxA and –B expression in different tissues of adult animals.Quantification of MgRunxA and –B expression by qRT-PCR (A). Whereas MgRunxB was only weakly expressed in all tissues analyzed, MgRunxA showed a strong expression in calcified cartilage gills and soft cartilage. Expression of MgRunxA was...
PMC2265548_pone-0001834-g009_18675.jpg
What is the principal component of this image?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18671.jpg
What is the central feature of this picture?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18673.jpg
What does this image primarily show?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18670.jpg
What is the focal point of this photograph?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18674.jpg
What key item or scene is captured in this photo?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18672.jpg
What is the core subject represented in this visual?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265548_pone-0001834-g009_18668.jpg
What is shown in this image?
T40/IDE digestion products form amyloid protofibrils.Electron micrographs of negatively stained AChE586-599 and AChE586-599 mutants showing fibrils (A) and protofibrils (B). The white arrows in the left panel indicate thinner fibrils, and the black arrows indicate twists in the fibrils (A).
PMC2265549_pone-0001814-g005_18676.jpg
What is shown in this image?
Enhanced loading of cell surface MHC by peptide-MLE.a) Confocal laser scanning analysis of cell surface loading. 721.221-DRb1GFP cells expressing a GFP-tagged HLA-DR1 molecule were incubated with biotinylated HA306-318 peptide in the absence or presence of Ac-FR-NH2. After staining with streptavidin-Cy5 images were tak...
PMC2265549_pone-0001814-g005_18677.jpg
What is shown in this image?
Enhanced loading of cell surface MHC by peptide-MLE.a) Confocal laser scanning analysis of cell surface loading. 721.221-DRb1GFP cells expressing a GFP-tagged HLA-DR1 molecule were incubated with biotinylated HA306-318 peptide in the absence or presence of Ac-FR-NH2. After staining with streptavidin-Cy5 images were tak...
PMC2265554_pone-0001828-g005_18681.jpg
What is the central feature of this picture?
Lung metastases' macroscopic analysis.At 45 days after tumor cells injection, the animals injected with K5L and K5L-Luc cells were sacrificed. Macroscopic surface metastases were observed in all lungs (A). The lungs of the mice injected with K5L cells were removed and stained with India ink (B).Using IVIS we analyzed l...
PMC2265554_pone-0001828-g005_18683.jpg
Can you identify the primary element in this image?
Lung metastases' macroscopic analysis.At 45 days after tumor cells injection, the animals injected with K5L and K5L-Luc cells were sacrificed. Macroscopic surface metastases were observed in all lungs (A). The lungs of the mice injected with K5L cells were removed and stained with India ink (B).Using IVIS we analyzed l...
PMC2265639_pone-0001641-g001_18688.jpg
What is the central feature of this picture?
Evidence of the presence of morphine-like immunoreactivity in secretory granules. A. Upper panel, double immunofluorescence confocal micrographs. Labeling was performed with a sheep anti-morphine antibody (visualized in green with an Alexa Fluor 488-conjugated IgG) and with an antibody against CGA (a specific intragran...
PMC2265639_pone-0001641-g001_18691.jpg
What object or scene is depicted here?
Evidence of the presence of morphine-like immunoreactivity in secretory granules. A. Upper panel, double immunofluorescence confocal micrographs. Labeling was performed with a sheep anti-morphine antibody (visualized in green with an Alexa Fluor 488-conjugated IgG) and with an antibody against CGA (a specific intragran...
PMC2265639_pone-0001641-g001_18687.jpg
What is the central feature of this picture?
Evidence of the presence of morphine-like immunoreactivity in secretory granules. A. Upper panel, double immunofluorescence confocal micrographs. Labeling was performed with a sheep anti-morphine antibody (visualized in green with an Alexa Fluor 488-conjugated IgG) and with an antibody against CGA (a specific intragran...
PMC2265639_pone-0001641-g001_18685.jpg
What is being portrayed in this visual content?
Evidence of the presence of morphine-like immunoreactivity in secretory granules. A. Upper panel, double immunofluorescence confocal micrographs. Labeling was performed with a sheep anti-morphine antibody (visualized in green with an Alexa Fluor 488-conjugated IgG) and with an antibody against CGA (a specific intragran...
PMC2265671_F1_18693.jpg
What is being portrayed in this visual content?
A, C, E: Paraffin sagittal sections through the subcommissural organ (SCO) of a PN2 rat after a single injection of AFRU into a lateral ventricle (inset 1C, labeled Ab). A: Immunostaining using AFRU (raised in rabbits) as primary antibody. The SCO is immunoreactive. Arrow points to RF-material. Insert: Detailed magnifi...
PMC2265671_F1_18695.jpg
What is the principal component of this image?
A, C, E: Paraffin sagittal sections through the subcommissural organ (SCO) of a PN2 rat after a single injection of AFRU into a lateral ventricle (inset 1C, labeled Ab). A: Immunostaining using AFRU (raised in rabbits) as primary antibody. The SCO is immunoreactive. Arrow points to RF-material. Insert: Detailed magnifi...
PMC2265682_F3_18703.jpg
Describe the main subject of this image.
Pin migration. Lateral radiograph of the right elbow 2 years after TBW of an isolated olecranon fracture in a 42-year-old woman. Despite fracture union, backing out of K-wires was evident. The patient was complaining for pain during elbow movements (VAS pain subjective score = 4) and skin irritation. Removal of metalwo...
PMC2265682_F6_18699.jpg
What stands out most in this visual?
Elbow degeneration and olecranon fracture. Mayo Type IIA fracture of the left olecranon after a fall in a 52-year-old woman (A). Lateral (B) and anteroposterior radiographs (C) at 7 years postoperatively showed signs of subchondral sclerosis and osteophytes formation in radioulnar and ulnohumeral joints.
PMC2265682_F6_18701.jpg
What is the main focus of this visual representation?
Elbow degeneration and olecranon fracture. Mayo Type IIA fracture of the left olecranon after a fall in a 52-year-old woman (A). Lateral (B) and anteroposterior radiographs (C) at 7 years postoperatively showed signs of subchondral sclerosis and osteophytes formation in radioulnar and ulnohumeral joints.
PMC2265682_F6_18700.jpg
What's the most prominent thing you notice in this picture?
Elbow degeneration and olecranon fracture. Mayo Type IIA fracture of the left olecranon after a fall in a 52-year-old woman (A). Lateral (B) and anteroposterior radiographs (C) at 7 years postoperatively showed signs of subchondral sclerosis and osteophytes formation in radioulnar and ulnohumeral joints.
PMC2265710_F3_18713.jpg
What key item or scene is captured in this photo?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18712.jpg
What is the main focus of this visual representation?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18711.jpg
Can you identify the primary element in this image?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18704.jpg
What does this image primarily show?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18709.jpg
Describe the main subject of this image.
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18706.jpg
What is the principal component of this image?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18714.jpg
What is the central feature of this picture?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18707.jpg
What can you see in this picture?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F3_18716.jpg
What is being portrayed in this visual content?
Analysis of transcription factors restricted to neural progenitor cell domains in transgenic cells overexpressing CyclinD. Immunodetection of (a-d) Sox2, (e-h) Olig2, (i-l) Pax6, and (m-p) Pax7, showing that transgenic cells (green) co-express markers of the ventricular zone (yellow cells) only when located within that...
PMC2265710_F5_18723.jpg
What key item or scene is captured in this photo?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18718.jpg
What is the principal component of this image?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18717.jpg
What's the most prominent thing you notice in this picture?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18724.jpg
What is the core subject represented in this visual?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18720.jpg
Describe the main subject of this image.
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18719.jpg
Can you identify the primary element in this image?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18725.jpg
What is the principal component of this image?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265710_F5_18721.jpg
What key item or scene is captured in this photo?
Cell cycle exit is not required for initiation or progression of neuronal differentiation.(a-d) Immunodetection of Ngn2 (red) after 48 h of CyclinD1 forced expression. The transgenic cells located in the motor neuron differentiating field do not retain Ngn2 expression. (a-d) maximum projections; (c,d) high magnificatio...
PMC2265720_F3_18731.jpg
What stands out most in this visual?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265720_F3_18733.jpg
What is shown in this image?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265720_F3_18728.jpg
What is the main focus of this visual representation?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265720_F3_18732.jpg
What is the core subject represented in this visual?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265720_F3_18726.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265720_F3_18729.jpg
What object or scene is depicted here?
Immunohistochemical expression of FOXM1 in normal breast tissue as well as in non-invasive and invasive breast tumours using a tissue microarray. (A, B) Normal breast tissue is detected with very weak FOXM1 expression in the nucleus (IRS = 1) and weak FOXM1 expression in the cytoplasm (IRS = 4). (C, D) In ductal carcin...
PMC2265766_pbio-0060051-g004_18734.jpg
What's the most prominent thing you notice in this picture?
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2265766_pbio-0060051-g004_18742.jpg
Describe the main subject of this image.
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2265766_pbio-0060051-g004_18737.jpg
What does this image primarily show?
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2265766_pbio-0060051-g004_18740.jpg
What can you see in this picture?
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2265766_pbio-0060051-g004_18736.jpg
What is the main focus of this visual representation?
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2265766_pbio-0060051-g004_18738.jpg
What key item or scene is captured in this photo?
Dynamic Redistribution of EYFP-Tagged CK-B during Phagocytosis.Time-lapse microscopy of zymosan (A and D), COZ (B and E), or IgG-opsonized zymosan (C and F) uptake in RAW 264.7 cells stably transfected with EYFP-CK-B (A–C) or EYFP (D–F). Photos represent a single frame at the peak of accumulation from a time-lapse reco...
PMC2266717_F1_18748.jpg
What object or scene is depicted here?
CT scan on admission. Computed tomography on admission shows peripancreatic oedema, thickening of the Gerota's fascia on the left side and at least two poorly defined fluid collections (in other cuts) corresponding to severe acute pancreatitis with Balthazar grade E [21].
PMC2266718_F1_18747.jpg
What is shown in this image?
CT scan of the abdomen in horizontal section showing a cystic mass.
PMC2266719_F4_18762.jpg
What is the core subject represented in this visual?
Morphological rescue of some moe- embryonic defects by injection of the epb4.1l5 constructs. (A) In wild-type embryos at 60 hpf, brain ventricles are visible, and the RPE is uniform (inset). (B) In moe- embryos, brain ventricles are reduced in size or absent, pericaridal edema is pronounced, and the RPE is patchy (inse...
PMC2266719_F4_18761.jpg
What does this image primarily show?
Morphological rescue of some moe- embryonic defects by injection of the epb4.1l5 constructs. (A) In wild-type embryos at 60 hpf, brain ventricles are visible, and the RPE is uniform (inset). (B) In moe- embryos, brain ventricles are reduced in size or absent, pericaridal edema is pronounced, and the RPE is patchy (inse...