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PMC2266934_F4_18885.jpg | What object or scene is depicted here? | GFP fluorescence monitors ductal and alveolar development in WOC and during mammary gland transplantation. (A-D) Mammary glands were cultured in IPAH media for a total of 10 days. On days 0 (A), 3 (B), 7 (C), and 10 (D) the mammary glands were briefly removed from the incubator to examine alveolar development as visual... |
PMC2266934_F4_18886.jpg | What's the most prominent thing you notice in this picture? | GFP fluorescence monitors ductal and alveolar development in WOC and during mammary gland transplantation. (A-D) Mammary glands were cultured in IPAH media for a total of 10 days. On days 0 (A), 3 (B), 7 (C), and 10 (D) the mammary glands were briefly removed from the incubator to examine alveolar development as visual... |
PMC2266934_F4_18887.jpg | What's the most prominent thing you notice in this picture? | GFP fluorescence monitors ductal and alveolar development in WOC and during mammary gland transplantation. (A-D) Mammary glands were cultured in IPAH media for a total of 10 days. On days 0 (A), 3 (B), 7 (C), and 10 (D) the mammary glands were briefly removed from the incubator to examine alveolar development as visual... |
PMC2266934_F4_18883.jpg | What is the principal component of this image? | GFP fluorescence monitors ductal and alveolar development in WOC and during mammary gland transplantation. (A-D) Mammary glands were cultured in IPAH media for a total of 10 days. On days 0 (A), 3 (B), 7 (C), and 10 (D) the mammary glands were briefly removed from the incubator to examine alveolar development as visual... |
PMC2266934_F5_18897.jpg | What does this image primarily show? | Surgical exposure of the mammary gland for GFP imaging does not inhibit subsequent gland development. A 4-week-old GFP mouse was anesthetized and one #4 mammary gland exposed in vivo and imaged. The epithelial tree is clearly visible, branching out from the nipple (^). (A) The lymph node (*) is visible at the junction ... |
PMC2266934_F5_18899.jpg | What is the core subject represented in this visual? | Surgical exposure of the mammary gland for GFP imaging does not inhibit subsequent gland development. A 4-week-old GFP mouse was anesthetized and one #4 mammary gland exposed in vivo and imaged. The epithelial tree is clearly visible, branching out from the nipple (^). (A) The lymph node (*) is visible at the junction ... |
PMC2266934_F5_18896.jpg | What is shown in this image? | Surgical exposure of the mammary gland for GFP imaging does not inhibit subsequent gland development. A 4-week-old GFP mouse was anesthetized and one #4 mammary gland exposed in vivo and imaged. The epithelial tree is clearly visible, branching out from the nipple (^). (A) The lymph node (*) is visible at the junction ... |
PMC2266934_F5_18898.jpg | What is the core subject represented in this visual? | Surgical exposure of the mammary gland for GFP imaging does not inhibit subsequent gland development. A 4-week-old GFP mouse was anesthetized and one #4 mammary gland exposed in vivo and imaged. The epithelial tree is clearly visible, branching out from the nipple (^). (A) The lymph node (*) is visible at the junction ... |
PMC2266934_F6_18900.jpg | Describe the main subject of this image. | Ultrasound can detect nonpalpable lesions in the mammary gland of transgenic mice. (A) Fourth mammary gland ultrasound image from a control wild-type mouse illustrating the homogeneous texture of the mammary gland tissue that surrounds the centrally located lymph node (*) with lines indicating the border of the #4 mamm... |
PMC2266934_F6_18902.jpg | What's the most prominent thing you notice in this picture? | Ultrasound can detect nonpalpable lesions in the mammary gland of transgenic mice. (A) Fourth mammary gland ultrasound image from a control wild-type mouse illustrating the homogeneous texture of the mammary gland tissue that surrounds the centrally located lymph node (*) with lines indicating the border of the #4 mamm... |
PMC2266934_F7_18894.jpg | Describe the main subject of this image. | Ultrasound can distinguish between different lesions in transgenic mice in vivo. Possible applications are to identify and follow mammary tumor development and progression over time (A-C) and compare to the appearance of tumor at time of necropsy (D), identify liver metastasis (E-F), distinguish between adenocarcinoma ... |
PMC2266934_F7_18891.jpg | Can you identify the primary element in this image? | Ultrasound can distinguish between different lesions in transgenic mice in vivo. Possible applications are to identify and follow mammary tumor development and progression over time (A-C) and compare to the appearance of tumor at time of necropsy (D), identify liver metastasis (E-F), distinguish between adenocarcinoma ... |
PMC2266934_F7_18895.jpg | What's the most prominent thing you notice in this picture? | Ultrasound can distinguish between different lesions in transgenic mice in vivo. Possible applications are to identify and follow mammary tumor development and progression over time (A-C) and compare to the appearance of tumor at time of necropsy (D), identify liver metastasis (E-F), distinguish between adenocarcinoma ... |
PMC2266936_F2_18909.jpg | What is the focal point of this photograph? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18912.jpg | Can you identify the primary element in this image? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18915.jpg | What is the focal point of this photograph? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18906.jpg | What is the core subject represented in this visual? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18905.jpg | What object or scene is depicted here? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18907.jpg | What is shown in this image? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18910.jpg | What does this image primarily show? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18917.jpg | What is shown in this image? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18916.jpg | What is the dominant medical problem in this image? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18911.jpg | What stands out most in this visual? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F2_18914.jpg | What is shown in this image? | Morphological change of human glioblastoma cells by gamma-irradiation. Phase microphotographs of cultured radio-resistant tumor cells of A172, GBM2, and U87MG cells (× 200 magnification) at various culture passages after gamma-radiation. Scale bars, 50 μm. |
PMC2266936_F7_18923.jpg | What does this image primarily show? | In vivo tumorigeneisis of radio-resistant cells derived from human glioblastoma cells by transplanted subpopulation in SCID mouse. Mice were transplanted with radio-resistant A172 cells (A-C) or GBM2 cells (D-F) into the right striatum via stereotaxic injection, and sacrificed at 4 weeks post-transplantation. Frozen se... |
PMC2266936_F7_18922.jpg | What is the dominant medical problem in this image? | In vivo tumorigeneisis of radio-resistant cells derived from human glioblastoma cells by transplanted subpopulation in SCID mouse. Mice were transplanted with radio-resistant A172 cells (A-C) or GBM2 cells (D-F) into the right striatum via stereotaxic injection, and sacrificed at 4 weeks post-transplantation. Frozen se... |
PMC2266936_F7_18921.jpg | What is shown in this image? | In vivo tumorigeneisis of radio-resistant cells derived from human glioblastoma cells by transplanted subpopulation in SCID mouse. Mice were transplanted with radio-resistant A172 cells (A-C) or GBM2 cells (D-F) into the right striatum via stereotaxic injection, and sacrificed at 4 weeks post-transplantation. Frozen se... |
PMC2266936_F7_18920.jpg | What is the dominant medical problem in this image? | In vivo tumorigeneisis of radio-resistant cells derived from human glioblastoma cells by transplanted subpopulation in SCID mouse. Mice were transplanted with radio-resistant A172 cells (A-C) or GBM2 cells (D-F) into the right striatum via stereotaxic injection, and sacrificed at 4 weeks post-transplantation. Frozen se... |
PMC2266936_F8_18926.jpg | What can you see in this picture? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18927.jpg | What is the principal component of this image? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18937.jpg | What can you see in this picture? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18935.jpg | What's the most prominent thing you notice in this picture? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18929.jpg | What is the main focus of this visual representation? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18928.jpg | What is the dominant medical problem in this image? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18936.jpg | What object or scene is depicted here? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18925.jpg | What is being portrayed in this visual content? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18934.jpg | Describe the main subject of this image. | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266936_F8_18933.jpg | What is the focal point of this photograph? | Immunocytochemical characteristics of brain tumor mass from SCID mouse transplanted with radio-resistant cancer stem cells derived from human gliobalstoma cells. Frozen sections of brain tumors were labeled with antibodies to human-nuclei to recognize engrafted human gliobalstoma cells (Red) or von Willebrand factor to... |
PMC2266937_F1_18940.jpg | What is shown in this image? | In situ hybridization of peripherin. The expression of peripherin mRNA was studied with ISH. The autoradiogram in A shows a mouse brain section hybridized with a 35S-labelled peripherin probe. The selective staining of the TM nucleus is evident. In B, a digoxigenin labelled mRNA probe reveals the distribution of periph... |
PMC2266937_F1_18939.jpg | What is being portrayed in this visual content? | In situ hybridization of peripherin. The expression of peripherin mRNA was studied with ISH. The autoradiogram in A shows a mouse brain section hybridized with a 35S-labelled peripherin probe. The selective staining of the TM nucleus is evident. In B, a digoxigenin labelled mRNA probe reveals the distribution of periph... |
PMC2266994_pone-0001851-g004_18948.jpg | What is shown in this image? | Defects in bile duct formation in Notch2-cko mice using either the Notch2del2 or Notch2del3 alleles.A,B. Hematoxylin and eosin-stained sections at P7 of control littermate (CT) and Notch2-cko mice using the Notch2del2 allele. Bile ducts (arrow) are observed in the periportal region of the control littermate (A), but no... |
PMC2266994_pone-0001851-g004_18941.jpg | What does this image primarily show? | Defects in bile duct formation in Notch2-cko mice using either the Notch2del2 or Notch2del3 alleles.A,B. Hematoxylin and eosin-stained sections at P7 of control littermate (CT) and Notch2-cko mice using the Notch2del2 allele. Bile ducts (arrow) are observed in the periportal region of the control littermate (A), but no... |
PMC2266994_pone-0001851-g004_18944.jpg | What is the main focus of this visual representation? | Defects in bile duct formation in Notch2-cko mice using either the Notch2del2 or Notch2del3 alleles.A,B. Hematoxylin and eosin-stained sections at P7 of control littermate (CT) and Notch2-cko mice using the Notch2del2 allele. Bile ducts (arrow) are observed in the periportal region of the control littermate (A), but no... |
PMC2266994_pone-0001851-g004_18943.jpg | What can you see in this picture? | Defects in bile duct formation in Notch2-cko mice using either the Notch2del2 or Notch2del3 alleles.A,B. Hematoxylin and eosin-stained sections at P7 of control littermate (CT) and Notch2-cko mice using the Notch2del2 allele. Bile ducts (arrow) are observed in the periportal region of the control littermate (A), but no... |
PMC2266994_pone-0001851-g004_18945.jpg | What is the dominant medical problem in this image? | Defects in bile duct formation in Notch2-cko mice using either the Notch2del2 or Notch2del3 alleles.A,B. Hematoxylin and eosin-stained sections at P7 of control littermate (CT) and Notch2-cko mice using the Notch2del2 allele. Bile ducts (arrow) are observed in the periportal region of the control littermate (A), but no... |
PMC2266995_pone-0001896-g008_18958.jpg | What's the most prominent thing you notice in this picture? | The expression patterns of five neuropeptide markers within DIMM-expressing neurons of the PI.(A) DIMM and c929-GAL4 are co-localized within 16 PI neurons. (B) All dILP2-expressing neurons are DIMM-positive. (C) The two SIFa-positive neurons are both DIMM-positive. (D) The three DH 44-expressing neurons are all DIMM-po... |
PMC2266995_pone-0001896-g008_18950.jpg | What is being portrayed in this visual content? | The expression patterns of five neuropeptide markers within DIMM-expressing neurons of the PI.(A) DIMM and c929-GAL4 are co-localized within 16 PI neurons. (B) All dILP2-expressing neurons are DIMM-positive. (C) The two SIFa-positive neurons are both DIMM-positive. (D) The three DH 44-expressing neurons are all DIMM-po... |
PMC2267008_ppat-1000015-g002_18964.jpg | Describe the main subject of this image. | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267008_ppat-1000015-g002_18963.jpg | What is being portrayed in this visual content? | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267008_ppat-1000015-g002_18965.jpg | What key item or scene is captured in this photo? | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267008_ppat-1000015-g002_18962.jpg | What does this image primarily show? | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267008_ppat-1000015-g002_18961.jpg | What stands out most in this visual? | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267008_ppat-1000015-g002_18960.jpg | What is the principal component of this image? | The MA-TC tag does not affect Gag localization.HeLa cells (top panel) were transfected with pNL4-3/MA-TC or 1GA or 29KE/31KE derivatives. Cells were labeled with FlAsH for 5 min at 37°C, washed, fixed in 3.7% formaldehyde, and examined microscopically. MDMs (bottom panel) were infected with VSV-G- pseudotyped virus sto... |
PMC2267165_F1_18966.jpg | Can you identify the primary element in this image? | Computed tomography demonstrating gas in all muscle compartments of the left thigh. |
PMC2267165_F2_18968.jpg | Describe the main subject of this image. | Computed tomography demonstrating gas in the left gluteal muscles and left psoas. |
PMC2267172_F3_18970.jpg | What's the most prominent thing you notice in this picture? | sagital radiograph of the Cut prosthesis. Figure 2 is showing the anteroposterior, figure 3 is showing the sagital radiograph 12 months after implantation of the implant in a 50 year old male patient. |
PMC2267191_F1_18971.jpg | What is the main focus of this visual representation? | CT scan showing a voluminous intraperitoneal mass 33 × 30 × 17 cm in size, occupying the most part of the abdomen, with solid and cystic parts and with peripheral contrast enhancement. |
PMC2267191_F3_18973.jpg | What is being portrayed in this visual content? | The tumor consists of sheets and aggregates of closely packed polygonal cell (hematoxylin and eosin, original magnification 100×), with abundant somewhat granular cytoplasm, as seen in the epitheliod type (inset, hematoxylin and eosin, original magnification 400×). |
PMC2267191_F3_18974.jpg | What is the focal point of this photograph? | The tumor consists of sheets and aggregates of closely packed polygonal cell (hematoxylin and eosin, original magnification 100×), with abundant somewhat granular cytoplasm, as seen in the epitheliod type (inset, hematoxylin and eosin, original magnification 400×). |
PMC2267203_F1_18975.jpg | What object or scene is depicted here? | Chest CT scan showing a well-circumscribed homogeneous pulmonary mass (4 cm) within the lingual of the left lung in a newly diagnosed child with ulcerative colitis. |
PMC2267204_F2_18976.jpg | What is being portrayed in this visual content? | Photograph of right breast keloid scarring following bilateral breast reduction. |
PMC2267220_pone-0001894-g002_18980.jpg | What is the focal point of this photograph? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18981.jpg | What key item or scene is captured in this photo? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18984.jpg | What is shown in this image? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18985.jpg | Describe the main subject of this image. | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18978.jpg | What's the most prominent thing you notice in this picture? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18982.jpg | What is the central feature of this picture? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18983.jpg | What is the main focus of this visual representation? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267220_pone-0001894-g002_18987.jpg | What is the dominant medical problem in this image? | Morphologic and immunohistochemical study of allograft, stented allograft and native artery.A & B: H&E stained tissue section shown at ×20–40 (top row) and ×200 (second row) magnifications with * denoting location of stent struts removed post-mortem. C: Dual labeling for the macrophage marker RAM-11 (brown) and the SMC... |
PMC2267466_F1_18990.jpg | What does this image primarily show? | MRI brain. Axial T2 image showing multiple white matter lesions, especially in the corpus callosum. The arrows point to only two of several callosal lesions. Early in the disease, callosal lesions are usually best seen on thin section sagittal FLAIR and sagittal T1 images, with contrast. |
PMC2267466_F4_18995.jpg | What is being portrayed in this visual content? | MRI brain. Sagittal T1 image showing the pathognomonic central callosal "holes" (microinfarcts) of SS. These residual "holes" (and sometimes, "spokes") develop as the acute callosal changes resolve. |
PMC2267467_F2_18992.jpg | Describe the main subject of this image. | Magnetic resonance imaging (MRI) revealed a well-defined mass located at the plantar forefoot with no apparent bone infiltration. |
PMC2267467_F2_18993.jpg | Can you identify the primary element in this image? | Magnetic resonance imaging (MRI) revealed a well-defined mass located at the plantar forefoot with no apparent bone infiltration. |
PMC2267467_F2_18991.jpg | What's the most prominent thing you notice in this picture? | Magnetic resonance imaging (MRI) revealed a well-defined mass located at the plantar forefoot with no apparent bone infiltration. |
PMC2267469_F1_18996.jpg | What is the main focus of this visual representation? | Computer Tomography showed an abdominal wall tumour (arrowed) arising from the left anterior abdominal wall muscles, in particular the internal oblique and transversus abdominis. |
PMC2267469_F3_19002.jpg | What is the principal component of this image? | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267469_F3_19004.jpg | What is being portrayed in this visual content? | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267469_F3_19003.jpg | What stands out most in this visual? | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267469_F3_19001.jpg | What is the core subject represented in this visual? | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267469_F3_19005.jpg | Describe the main subject of this image. | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267469_F3_19000.jpg | What is the main focus of this visual representation? | The microscopic features of the granular cell tumour were: (A) Round polygonal granular cells observed in nests, divided by fibrous septa; (B) The tumour had an infiltrating margin; (C) The nuclei were small and dark. The cytoplasm was eosinophilic fine to coarsely granular; (D) The granular cell tumour arose from the ... |
PMC2267470_F1_18999.jpg | What is the core subject represented in this visual? | Postoperative radiographs. |
PMC2267470_F1_18998.jpg | What is being portrayed in this visual content? | Postoperative radiographs. |
PMC2267470_F1_18997.jpg | Describe the main subject of this image. | Postoperative radiographs. |
PMC2267471_F1_19014.jpg | What object or scene is depicted here? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19008.jpg | What is shown in this image? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19006.jpg | What is the principal component of this image? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19007.jpg | What is the dominant medical problem in this image? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19009.jpg | What can you see in this picture? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19011.jpg | What is the main focus of this visual representation? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19010.jpg | What is the central feature of this picture? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19016.jpg | What is the principal component of this image? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267471_F1_19015.jpg | What can you see in this picture? | Neuroimaging of patient with occipital hemorrhage secondary to carotid dissection. A-B: Computerized tomography (CT) of the head showing left occipital hemorrhage. C: Diffusion weighted imaging (DWI). D, E, F: Axial, coronal, and sagital T1-weighted magnetic resonance imaging (MRI). G, H: Axial and coronal T2-weighted ... |
PMC2267488_pgen-1000042-g002_19017.jpg | What is the principal component of this image? | Zip4h expression in testis sections.Testis sections from adult Zip4h+/Y (A, C) and Zip4h−/Y (B, D) mice were immunohistochemically labeled for ZIP4H (in brown), and counterstained with hematoxylin (in blue). Staining patterns under low magnification (A, B). Higher magnification images showing positively stained zygoten... |
PMC2267488_pgen-1000042-g002_19020.jpg | What does this image primarily show? | Zip4h expression in testis sections.Testis sections from adult Zip4h+/Y (A, C) and Zip4h−/Y (B, D) mice were immunohistochemically labeled for ZIP4H (in brown), and counterstained with hematoxylin (in blue). Staining patterns under low magnification (A, B). Higher magnification images showing positively stained zygoten... |
PMC2267690_f3_19023.jpg | What is being portrayed in this visual content? | Histologic findings of the human corneal endothelial cell sheet. A and B: A cell sheet consists of a monolayer of cells that have consistent size. The scale bar in A is equal to 200 μm and in B is equal to 50 μm. C: Electron microscopic observation demonstrated desmosomes between cells (arrow). Bar=200 nm. |
PMC2267690_f4_19025.jpg | What is the focal point of this photograph? | Immunohistologic findings of the human corneal endothelial cell sheet. A and B: In the flat mount immunohistochemical observation, immunostaining of both ZO-1 (A) and Na+, K+-ATPase (B) were positive at most cellular boundaries. The cellular shape demarcated with immunostaining was quasi-regular with well defined cell ... |
PMC2267690_f4_19024.jpg | What object or scene is depicted here? | Immunohistologic findings of the human corneal endothelial cell sheet. A and B: In the flat mount immunohistochemical observation, immunostaining of both ZO-1 (A) and Na+, K+-ATPase (B) were positive at most cellular boundaries. The cellular shape demarcated with immunostaining was quasi-regular with well defined cell ... |
PMC2267726_f1_19032.jpg | What is being portrayed in this visual content? | Electron micrographs of fibrils negatively stained with 1% uranyl acetate. Conditions were as follows: A: 5 mg/ml solution of the HγD-Crys into 50 mM acetate buffer pH 3 incubated at 37 °C for 2 days, B: 5 mg/ml solution of the HγD-Crys Ctd into 50 mM acetate buffer pH 3 incubated at 37 °C for 2 days, C: 5 mg/ml soluti... |
PMC2267726_f1_19030.jpg | What is being portrayed in this visual content? | Electron micrographs of fibrils negatively stained with 1% uranyl acetate. Conditions were as follows: A: 5 mg/ml solution of the HγD-Crys into 50 mM acetate buffer pH 3 incubated at 37 °C for 2 days, B: 5 mg/ml solution of the HγD-Crys Ctd into 50 mM acetate buffer pH 3 incubated at 37 °C for 2 days, C: 5 mg/ml soluti... |
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