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PMC2329822_fig07_20687.jpg | What is the main focus of this visual representation? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20692.jpg | What key item or scene is captured in this photo? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20696.jpg | What is the dominant medical problem in this image? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20695.jpg | What is being portrayed in this visual content? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20691.jpg | What is the core subject represented in this visual? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20690.jpg | What can you see in this picture? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20694.jpg | What key item or scene is captured in this photo? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20689.jpg | What is the focal point of this photograph? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20700.jpg | What stands out most in this visual? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20688.jpg | What is the central feature of this picture? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329822_fig07_20698.jpg | What is the focal point of this photograph? | Slp2-a localizes predominantly to the plasma membrane and focuses at the immunological synapseMouse Slp2-a tagged with pmaxGFP at either the amino terminus (panels A–C) or the carboxy terminus (panels D–I) expressed in RBL cells (panels A–I). Panels A, D and G show GFP fluorescence, and B and E show staining with anti-... |
PMC2329910_pone-0002131-g004_20706.jpg | What key item or scene is captured in this photo? | Co-transfection of gM truncation mutants with gN.A. Each gM-eGFP mutant (T1–T4) or the corresponding full-length form (gM-FL-eGFP) was transfected into 293T cells with or without co-transfected gN. We tested 2 independent gM-T1-eGFP plasmid preparations (1.1, 1.2) to allow for possible poor transfection efficiency. At ... |
PMC2329910_pone-0002131-g004_20704.jpg | What's the most prominent thing you notice in this picture? | Co-transfection of gM truncation mutants with gN.A. Each gM-eGFP mutant (T1–T4) or the corresponding full-length form (gM-FL-eGFP) was transfected into 293T cells with or without co-transfected gN. We tested 2 independent gM-T1-eGFP plasmid preparations (1.1, 1.2) to allow for possible poor transfection efficiency. At ... |
PMC2329910_pone-0002131-g004_20705.jpg | What is the focal point of this photograph? | Co-transfection of gM truncation mutants with gN.A. Each gM-eGFP mutant (T1–T4) or the corresponding full-length form (gM-FL-eGFP) was transfected into 293T cells with or without co-transfected gN. We tested 2 independent gM-T1-eGFP plasmid preparations (1.1, 1.2) to allow for possible poor transfection efficiency. At ... |
PMC2329910_pone-0002131-g005_20702.jpg | What key item or scene is captured in this photo? | Viral protein distribution in cells infected with viable gM cytoplasmic tail truncation mutants.NIH-3T3 cells were infected with with full-length (FL) or truncated gM-eGFP virus mutants (T2–T4) as shown (0.3 p.f.u./cell, 18 h), then fixed in 2% paraformaldehyde and stained for thymidine kinase, gN or the ORF65 capsid c... |
PMC2329910_pone-0002131-g005_20703.jpg | What is the principal component of this image? | Viral protein distribution in cells infected with viable gM cytoplasmic tail truncation mutants.NIH-3T3 cells were infected with with full-length (FL) or truncated gM-eGFP virus mutants (T2–T4) as shown (0.3 p.f.u./cell, 18 h), then fixed in 2% paraformaldehyde and stained for thymidine kinase, gN or the ORF65 capsid c... |
PMC2329910_pone-0002131-g005_20701.jpg | Can you identify the primary element in this image? | Viral protein distribution in cells infected with viable gM cytoplasmic tail truncation mutants.NIH-3T3 cells were infected with with full-length (FL) or truncated gM-eGFP virus mutants (T2–T4) as shown (0.3 p.f.u./cell, 18 h), then fixed in 2% paraformaldehyde and stained for thymidine kinase, gN or the ORF65 capsid c... |
PMC2330022_F2_20717.jpg | What is the principal component of this image? | Sinonasal meningeoma. CT scan in bone window (A, D) reveals a soft tissue mass in the left frontal sinus without any signs of bone destruction or reaction. Axial T2 weighted images (B), T1 weighted images before (C) and after contrast administration (E, F) show a contrast enhancing soft tissue mass being slightly inhom... |
PMC2330022_F2_20720.jpg | What is being portrayed in this visual content? | Sinonasal meningeoma. CT scan in bone window (A, D) reveals a soft tissue mass in the left frontal sinus without any signs of bone destruction or reaction. Axial T2 weighted images (B), T1 weighted images before (C) and after contrast administration (E, F) show a contrast enhancing soft tissue mass being slightly inhom... |
PMC2330022_F2_20721.jpg | What is the main focus of this visual representation? | Sinonasal meningeoma. CT scan in bone window (A, D) reveals a soft tissue mass in the left frontal sinus without any signs of bone destruction or reaction. Axial T2 weighted images (B), T1 weighted images before (C) and after contrast administration (E, F) show a contrast enhancing soft tissue mass being slightly inhom... |
PMC2330022_F2_20718.jpg | What is the dominant medical problem in this image? | Sinonasal meningeoma. CT scan in bone window (A, D) reveals a soft tissue mass in the left frontal sinus without any signs of bone destruction or reaction. Axial T2 weighted images (B), T1 weighted images before (C) and after contrast administration (E, F) show a contrast enhancing soft tissue mass being slightly inhom... |
PMC2330022_F3_20723.jpg | Describe the main subject of this image. | Extracranial craniopharyngeoma. A-C: Coronal, axial and sagittal reconstructions of a spiral CT scan. Note the expansively growing mass with calcifications, thinning and remodeling of the walls of the pterygoid processes, predominantly on the right side, and the anterior parts of the clivus with preserved posterior mar... |
PMC2330022_F3_20722.jpg | What does this image primarily show? | Extracranial craniopharyngeoma. A-C: Coronal, axial and sagittal reconstructions of a spiral CT scan. Note the expansively growing mass with calcifications, thinning and remodeling of the walls of the pterygoid processes, predominantly on the right side, and the anterior parts of the clivus with preserved posterior mar... |
PMC2330022_F3_20727.jpg | What can you see in this picture? | Extracranial craniopharyngeoma. A-C: Coronal, axial and sagittal reconstructions of a spiral CT scan. Note the expansively growing mass with calcifications, thinning and remodeling of the walls of the pterygoid processes, predominantly on the right side, and the anterior parts of the clivus with preserved posterior mar... |
PMC2330022_F3_20725.jpg | What is the central feature of this picture? | Extracranial craniopharyngeoma. A-C: Coronal, axial and sagittal reconstructions of a spiral CT scan. Note the expansively growing mass with calcifications, thinning and remodeling of the walls of the pterygoid processes, predominantly on the right side, and the anterior parts of the clivus with preserved posterior mar... |
PMC2330022_F5_20709.jpg | What is the dominant medical problem in this image? | Nasal glial heterotopia. A: Coronal reconstruction of a spiral CT scan. A soft tissue mass is visible in left nasal cavity. Note the incomplete ossification of the skull base (arrow) at the age of 48 days. Ossification is regularly completed in this area at the age of 3 months. B: Sagittal T2 weighted MR image revealin... |
PMC2330022_F5_20710.jpg | What is the focal point of this photograph? | Nasal glial heterotopia. A: Coronal reconstruction of a spiral CT scan. A soft tissue mass is visible in left nasal cavity. Note the incomplete ossification of the skull base (arrow) at the age of 48 days. Ossification is regularly completed in this area at the age of 3 months. B: Sagittal T2 weighted MR image revealin... |
PMC2330022_F6_20714.jpg | What is being portrayed in this visual content? | Histological findings of endonasal glial heterotopia. A: Subepithelial neuroglial tissue (H&E 10×). B: Astrocytes and capillaries embedded in a loose fibrillary matrix (H&E 40×). C: Immunohistochemical detection of glial fibrillary acidic protein (GFAP 20×). D: Focal immunohistochemical detection of synaptophysin (20×)... |
PMC2330022_F6_20715.jpg | What is shown in this image? | Histological findings of endonasal glial heterotopia. A: Subepithelial neuroglial tissue (H&E 10×). B: Astrocytes and capillaries embedded in a loose fibrillary matrix (H&E 40×). C: Immunohistochemical detection of glial fibrillary acidic protein (GFAP 20×). D: Focal immunohistochemical detection of synaptophysin (20×)... |
PMC2330022_F6_20713.jpg | What is the focal point of this photograph? | Histological findings of endonasal glial heterotopia. A: Subepithelial neuroglial tissue (H&E 10×). B: Astrocytes and capillaries embedded in a loose fibrillary matrix (H&E 40×). C: Immunohistochemical detection of glial fibrillary acidic protein (GFAP 20×). D: Focal immunohistochemical detection of synaptophysin (20×)... |
PMC2330022_F6_20712.jpg | What is the principal component of this image? | Histological findings of endonasal glial heterotopia. A: Subepithelial neuroglial tissue (H&E 10×). B: Astrocytes and capillaries embedded in a loose fibrillary matrix (H&E 40×). C: Immunohistochemical detection of glial fibrillary acidic protein (GFAP 20×). D: Focal immunohistochemical detection of synaptophysin (20×)... |
PMC2330026_F7_20735.jpg | What is the principal component of this image? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F7_20732.jpg | What key item or scene is captured in this photo? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F7_20736.jpg | What stands out most in this visual? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F7_20734.jpg | What is shown in this image? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F7_20731.jpg | What object or scene is depicted here? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F7_20737.jpg | What is the core subject represented in this visual? | Regression of hepatic, mesenteric and hilar melanoma metastases after DAB/IL2 administration. A. Patient P3 was scanned by combination PET/CT imaging 2 weeks prior to DAB/IL2 administration (pre-DAB/IL2) and after completing four 3-week cycles of DAB/IL2 (post-DAB/IL2). The brain, heart and bladder have normal accumula... |
PMC2330026_F9_20729.jpg | What is the focal point of this photograph? | Stabilization of two right hilar masses in a 79-year old male after DAB/IL2 administration. PET imaging of patient P12 was conducted 1 month prior and 3 months after 2 cycles of DAB/IL2. Two discrete areas of hypermetabolism in the right hilum remained stable during this three month period. |
PMC2330026_F9_20730.jpg | Describe the main subject of this image. | Stabilization of two right hilar masses in a 79-year old male after DAB/IL2 administration. PET imaging of patient P12 was conducted 1 month prior and 3 months after 2 cycles of DAB/IL2. Two discrete areas of hypermetabolism in the right hilum remained stable during this three month period. |
PMC2330026_F9_20728.jpg | What does this image primarily show? | Stabilization of two right hilar masses in a 79-year old male after DAB/IL2 administration. PET imaging of patient P12 was conducted 1 month prior and 3 months after 2 cycles of DAB/IL2. Two discrete areas of hypermetabolism in the right hilum remained stable during this three month period. |
PMC2330026_F10_20739.jpg | What is the focal point of this photograph? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20747.jpg | What does this image primarily show? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20745.jpg | What does this image primarily show? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20746.jpg | What is the main focus of this visual representation? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20748.jpg | What is the main focus of this visual representation? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20743.jpg | What key item or scene is captured in this photo? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20741.jpg | Can you identify the primary element in this image? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20742.jpg | What's the most prominent thing you notice in this picture? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20750.jpg | Describe the main subject of this image. | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20753.jpg | What key item or scene is captured in this photo? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20749.jpg | What is the dominant medical problem in this image? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20751.jpg | What is the central feature of this picture? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20744.jpg | What is being portrayed in this visual content? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20740.jpg | What is the core subject represented in this visual? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330026_F10_20752.jpg | What is the dominant medical problem in this image? | Near complete response of widespread visceralmelanoma metastases after 4 cycles of DAB/IL2. A. Anterior/posterior views, PET. B. Lateral views, PET. C. CT imaging, liver. D. CT imaging, lungs. Combined PET/CT imaging of patient P14 revealed rapid progression of multiple melanoma metastases in the liver, both lungs, lym... |
PMC2330030_F2_20755.jpg | What object or scene is depicted here? | Computed tomography scan illustrates the "classic" features of IPF. Bilateral, peripheral, subpleural reticular infiltrates are evident. The presence of advanced fibrosis is indicated by honeycomb changes (arrowhead) and traction bronchiectasis (arrow). These features permit experienced clinicians to make a confident r... |
PMC2330030_F3_20756.jpg | What is the dominant medical problem in this image? | Computed tomography scan of an 81-year old man with biopsy-proven IPF. A peripheral distribution of reticular opacities is demonstrated. Honeycombing and traction bronchiectasis are notably absent. In the absence of specific findings, a surgical lung biopsy was needed to make a diagnosis. * Reprinted from Fishman's Pul... |
PMC2330030_F5_20757.jpg | Describe the main subject of this image. | Scanning view of UIP demonstrates the characteristic variegated appearance of UIP. Note the honeycomb change (arrowheads) present in the region of dense fibrosis adjacent to the pleural surface. A fibroblast focus (arrow) is seen at the leading edge of advancing fibrosis. * Reprinted from Fishman's Pulmonary Diseases a... |
PMC2330033_F7_20762.jpg | What is shown in this image? | Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 ra... |
PMC2330033_F7_20759.jpg | What object or scene is depicted here? | Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 ra... |
PMC2330033_F7_20765.jpg | What is the dominant medical problem in this image? | Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 ra... |
PMC2330033_F7_20758.jpg | What stands out most in this visual? | Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 ra... |
PMC2330033_F7_20767.jpg | What is being portrayed in this visual content? | Double immunostaining of IgG extravasation and the expression of GFAP. Cholesterol-enriched diet markedly enhanced the immunopositive staining of GFAP (green) around the sites where IgG extravasation (red) was present. These effects were blocked by caffeine at the dose of 3 mg/day. Representative images taken from 2 ra... |
PMC2330034_F1_20768.jpg | What does this image primarily show? | Immunofluorescence analysis of the localization of Stx receptor Gb3/CD77 in the rabbit CNS. Intense fluorescence was detected on the blood vessels of the spinal cord gray matter (A), whereas fluorescent signals were much weaker on those of the spinal cord white matter except anterior spinal artery (arrow) (B) and hippo... |
PMC2330034_F1_20770.jpg | Describe the main subject of this image. | Immunofluorescence analysis of the localization of Stx receptor Gb3/CD77 in the rabbit CNS. Intense fluorescence was detected on the blood vessels of the spinal cord gray matter (A), whereas fluorescent signals were much weaker on those of the spinal cord white matter except anterior spinal artery (arrow) (B) and hippo... |
PMC2330034_F1_20772.jpg | What is the focal point of this photograph? | Immunofluorescence analysis of the localization of Stx receptor Gb3/CD77 in the rabbit CNS. Intense fluorescence was detected on the blood vessels of the spinal cord gray matter (A), whereas fluorescent signals were much weaker on those of the spinal cord white matter except anterior spinal artery (arrow) (B) and hippo... |
PMC2330034_F1_20773.jpg | What is the main focus of this visual representation? | Immunofluorescence analysis of the localization of Stx receptor Gb3/CD77 in the rabbit CNS. Intense fluorescence was detected on the blood vessels of the spinal cord gray matter (A), whereas fluorescent signals were much weaker on those of the spinal cord white matter except anterior spinal artery (arrow) (B) and hippo... |
PMC2330034_F1_20769.jpg | What is the principal component of this image? | Immunofluorescence analysis of the localization of Stx receptor Gb3/CD77 in the rabbit CNS. Intense fluorescence was detected on the blood vessels of the spinal cord gray matter (A), whereas fluorescent signals were much weaker on those of the spinal cord white matter except anterior spinal artery (arrow) (B) and hippo... |
PMC2330057_F2_20774.jpg | What can you see in this picture? | CT scan showing a comminuted fracture of the sternum and retrosternal haematoma. |
PMC2330063_fig2_20778.jpg | What is shown in this image? | Group maps of the parahippocampal gyrus tracts comparing left TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In controls... |
PMC2330063_fig2_20777.jpg | What stands out most in this visual? | Group maps of the parahippocampal gyrus tracts comparing left TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In controls... |
PMC2330063_fig3_20782.jpg | What is the focal point of this photograph? | Group maps of the parahippocampal gyrus tracts comparing right TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In control... |
PMC2330063_fig3_20779.jpg | What is the dominant medical problem in this image? | Group maps of the parahippocampal gyrus tracts comparing right TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In control... |
PMC2330063_fig3_20780.jpg | What is the core subject represented in this visual? | Group maps of the parahippocampal gyrus tracts comparing right TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In control... |
PMC2330063_fig3_20781.jpg | What is being portrayed in this visual content? | Group maps of the parahippocampal gyrus tracts comparing right TLE patients against controls. Tracts are projected onto a 3d rendered brain template. A voxel commonality value of 1.0 indicates that each individual had a connection identified in this voxel while a value of 0.0 indicates that none of them did. In control... |
PMC2330066_fig6_20784.jpg | What key item or scene is captured in this photo? | Slice through MRI (a) and corresponding VBCT map (b). The VBCT map slice shows regions where the thickness values are greater than 5 mm. These regions correspond to sub-cortical structures and some voxels in the insular and cingulate cortex. |
PMC2330161_pone-0002127-g005_20786.jpg | What's the most prominent thing you notice in this picture? | Prolonged stimulation with glucose results in a biphasic pattern of cAMP accumulation in β-cells.A. A living islet from an induced Ins2-rtTA/pBI-cAMP mouse, viewed for YFP fluorescence. Dotted circles are ROIs analyzed functionally, and correspond to numbered traces in B. Scale bar, 20 µm. B. Prolonged glucose stimulat... |
PMC2335107_F7_20790.jpg | What is the core subject represented in this visual? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20796.jpg | What is the focal point of this photograph? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20799.jpg | What is the main focus of this visual representation? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20795.jpg | Describe the main subject of this image. | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20798.jpg | Describe the main subject of this image. | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20791.jpg | What is being portrayed in this visual content? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20794.jpg | What stands out most in this visual? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335107_F7_20797.jpg | What key item or scene is captured in this photo? | Histological examples of alveolar edema (25*), septal edema (100*) and intra-alveolar hemorrhage (40*) on HE slides. LIRI caused alveolar and septal edema and alveolar hemorrhages, which were most severe on day 1 and 3 after LIRI and resolved thereafter. On day 7 brownish macrophages were found after clearance of eryth... |
PMC2335109_F4_20802.jpg | What is the core subject represented in this visual? | Electron micrographs of S. parasanguinis bacteria. S. parasanguinis bacteria, L64R (A), P65R (B), I66N (C), L67T (D) mutant variants and wild type FW213 (E) were placed on grids, and negatively stained with 2% phosphotungstic acid pH7.0 and visualized by electron microscopy. White arrows point to the short fimbriae. Bl... |
PMC2335109_F4_20801.jpg | Describe the main subject of this image. | Electron micrographs of S. parasanguinis bacteria. S. parasanguinis bacteria, L64R (A), P65R (B), I66N (C), L67T (D) mutant variants and wild type FW213 (E) were placed on grids, and negatively stained with 2% phosphotungstic acid pH7.0 and visualized by electron microscopy. White arrows point to the short fimbriae. Bl... |
PMC2344115_fig07_20812.jpg | What's the most prominent thing you notice in this picture? | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2344115_fig07_20807.jpg | What is the principal component of this image? | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2344115_fig07_20809.jpg | What is the principal component of this image? | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2344115_fig07_20810.jpg | What is the focal point of this photograph? | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2344115_fig07_20808.jpg | Describe the main subject of this image. | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2344115_fig07_20811.jpg | What is being portrayed in this visual content? | Intracellular distribution of ectopically expressed EspJ during FcγR-dependent uptake. Cos-7 cells were co-transfected with FcγRIIa and either with pRK5-EspJFLAG (top) or with empty pRK5 (bottom) and challenged with IgG-opsonized RBC for 30 min at 37°C, as described in the legend to Fig. 5. RBC-challenged cells were pe... |
PMC2346456_F2_20816.jpg | What is shown in this image? | Segmental pedicle screw constructs. Lateral radiographs before and after surgery. |
PMC2346456_F2_20815.jpg | What key item or scene is captured in this photo? | Segmental pedicle screw constructs. Lateral radiographs before and after surgery. |
PMC2346456_F2_20814.jpg | Describe the main subject of this image. | Segmental pedicle screw constructs. Lateral radiographs before and after surgery. |
PMC2346456_F4_20817.jpg | What is the central feature of this picture? | Hybrid constructs using pedicle screws, hooks, and wires. Lateral radiographs before and after surgery. |
PMC2346456_F4_20818.jpg | What is the core subject represented in this visual? | Hybrid constructs using pedicle screws, hooks, and wires. Lateral radiographs before and after surgery. |
PMC2346456_F6_20820.jpg | What is being portrayed in this visual content? | Anterior instrumentation surgery. Lateral radiographs before and after surgery (By courtesy of Dr. Tomasz Kotwicki). |
PMC2346466_F3_20821.jpg | What is the main focus of this visual representation? | Expression of Nrg in (a, c, e) wild-type, (b) mutant rescue, (d) over-expression and (f) mutant embryos. All embryos were immuno-stained with mAb BP104, which recognizes an epitope on Nrg180. HRP-conjugated secondary antibody and bright field illumination was used in (a, b, e, f) and Alexa488-conjugated secondary antib... |
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