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PMC2346466_F3_20824.jpg | What's the most prominent thing you notice in this picture? | Expression of Nrg in (a, c, e) wild-type, (b) mutant rescue, (d) over-expression and (f) mutant embryos. All embryos were immuno-stained with mAb BP104, which recognizes an epitope on Nrg180. HRP-conjugated secondary antibody and bright field illumination was used in (a, b, e, f) and Alexa488-conjugated secondary antib... |
PMC2346466_F3_20823.jpg | What is being portrayed in this visual content? | Expression of Nrg in (a, c, e) wild-type, (b) mutant rescue, (d) over-expression and (f) mutant embryos. All embryos were immuno-stained with mAb BP104, which recognizes an epitope on Nrg180. HRP-conjugated secondary antibody and bright field illumination was used in (a, b, e, f) and Alexa488-conjugated secondary antib... |
PMC2346476_F7_20839.jpg | What is being portrayed in this visual content? | uri is required for male germline viability and differentiation. A, wild type testis from male pharate adult. Stem cells reside at the apical tip (asterisk), cells move distally as they mature so most of the apical region is taken up by maturing primary spermatocytes. Elongating spermatids are seen pushing up the lengt... |
PMC2346476_F7_20837.jpg | What is the dominant medical problem in this image? | uri is required for male germline viability and differentiation. A, wild type testis from male pharate adult. Stem cells reside at the apical tip (asterisk), cells move distally as they mature so most of the apical region is taken up by maturing primary spermatocytes. Elongating spermatids are seen pushing up the lengt... |
PMC2346477_F2_20831.jpg | What stands out most in this visual? | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346477_F2_20827.jpg | What key item or scene is captured in this photo? | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346477_F2_20832.jpg | What does this image primarily show? | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346477_F2_20833.jpg | Describe the main subject of this image. | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346477_F2_20828.jpg | What does this image primarily show? | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346477_F2_20834.jpg | What stands out most in this visual? | Immunocytochemistry images of HCC1937 cells. Immunocytochemistry images of HCC1937 cells transduced with Tat fusion proteins for 24 hours. (A) Cells treated with 2 μM E2F-1/TatHA. (B) Cells treated with 2 μM E132/TatHA. (C) Cells treated with 2 μM TatHA control peptide. Images were captured using the 40× objective on t... |
PMC2346482_F1_20843.jpg | What is the dominant medical problem in this image? | a) Presence of a psammoma body in absence of atypical cells in cervicovaginal smear (Papanicolaou stain, 200×); b) Serous ovarian cystoadenofibroma with parietal psammoma bodies (Hematoxylin and Eosin, 100×). |
PMC2346482_F1_20842.jpg | What does this image primarily show? | a) Presence of a psammoma body in absence of atypical cells in cervicovaginal smear (Papanicolaou stain, 200×); b) Serous ovarian cystoadenofibroma with parietal psammoma bodies (Hematoxylin and Eosin, 100×). |
PMC2346482_F2_20844.jpg | What does this image primarily show? | a) Psammoma body surrounded by atypical cells (arrows) in cervicovaginal smear (Papanicolaou stain, 200×); b) Psammoma body surrounded by atypical cells (arrows) in endometrial aspiration smear (Papanicolaou stain, 200×). |
PMC2346483_F1_20846.jpg | What is the central feature of this picture? | A: Aggregate of crystals on fine needle aspirate, Diff-Quik stain. B: Aggregate of crystals and few mononuclear cells, FNA cellblock, H&E stain. C: Birefringent crystals on polarized light microscopy of same area from cell block. D: Darkfield image showing crystals, same area from cellblock. E: Aggregate of crystals su... |
PMC2346483_F1_20851.jpg | What stands out most in this visual? | A: Aggregate of crystals on fine needle aspirate, Diff-Quik stain. B: Aggregate of crystals and few mononuclear cells, FNA cellblock, H&E stain. C: Birefringent crystals on polarized light microscopy of same area from cell block. D: Darkfield image showing crystals, same area from cellblock. E: Aggregate of crystals su... |
PMC2346483_F1_20847.jpg | What stands out most in this visual? | A: Aggregate of crystals on fine needle aspirate, Diff-Quik stain. B: Aggregate of crystals and few mononuclear cells, FNA cellblock, H&E stain. C: Birefringent crystals on polarized light microscopy of same area from cell block. D: Darkfield image showing crystals, same area from cellblock. E: Aggregate of crystals su... |
PMC2358884_F3_20855.jpg | What is shown in this image? | Histology: normal squamous epithelium (red arrows); carcinoma showing immature cells without keratosis which corresponds to a G3-grading (hematoxylin and eosin (HE) staining; magnification: 100×). |
PMC2358884_F4_20852.jpg | What is the dominant medical problem in this image? | Imaging by fluorine 18-fluoro-2-deoxy-glucose-positron emission tomography (18F-FDG-PET) anterior-posterior view. |
PMC2358884_F5_20854.jpg | Describe the main subject of this image. | Imaging by fluorine 18-fluoro-2-deoxy-glucose-positron emission tomography (18F-FDG-PET) lateral view. |
PMC2358907_F1_20861.jpg | What is the principal component of this image? | (Case 1).1a CT thorax showing filling defect in the right brachiocephalic vein (1) due to thrombus, while the left brachiocephalic vein (2) is patent and shows intense contrast enhancement. 1b CT neck showing patent left internal jugular vein with intense contrast enhancement due to regurgitation (3). Right internal ju... |
PMC2358907_F1_20860.jpg | What's the most prominent thing you notice in this picture? | (Case 1).1a CT thorax showing filling defect in the right brachiocephalic vein (1) due to thrombus, while the left brachiocephalic vein (2) is patent and shows intense contrast enhancement. 1b CT neck showing patent left internal jugular vein with intense contrast enhancement due to regurgitation (3). Right internal ju... |
PMC2358907_F7_20862.jpg | What's the most prominent thing you notice in this picture? | (Case 5).7a) Papillary carcinoma: papillary clusters of cells replacing large vessel with similar invasion of smaller vessels, top right (haematoxylin and eosin × 100). 7b) Papillary carcinoma higher magnification: papillae with fibrovascular cores, lined by crowded cells with nuclear clearing and occasional grooving (... |
PMC2358907_F7_20863.jpg | What can you see in this picture? | (Case 5).7a) Papillary carcinoma: papillary clusters of cells replacing large vessel with similar invasion of smaller vessels, top right (haematoxylin and eosin × 100). 7b) Papillary carcinoma higher magnification: papillae with fibrovascular cores, lined by crowded cells with nuclear clearing and occasional grooving (... |
PMC2359648_fig1_20864.jpg | What is being portrayed in this visual content? | Typical imaging features of a probably benign, circumscribed, discrete mass, graded 3B in our programme. (A) Mammogram, left lateral view, with the arrow pointing to a circumscribed mass. (B) Breast ultrasound of the lesion, showing a circumscribed oblong mass. (C) Ultrasound image, documenting the presence of the biop... |
PMC2359648_fig1_20866.jpg | Can you identify the primary element in this image? | Typical imaging features of a probably benign, circumscribed, discrete mass, graded 3B in our programme. (A) Mammogram, left lateral view, with the arrow pointing to a circumscribed mass. (B) Breast ultrasound of the lesion, showing a circumscribed oblong mass. (C) Ultrasound image, documenting the presence of the biop... |
PMC2359648_fig2_20868.jpg | What can you see in this picture? | Biopsy features of a case shown to be a fibroadenoma. (A) Low power photomicrograph of a fine needle aspiration biopsy of a discrete solid mass, showing mono-layered sheets of cohesive cells in a background of bipolar cells. (B) Cohesive sheet of cells together with smaller cell clusters with a tendency to dissociation... |
PMC2359648_fig2_20871.jpg | What is the dominant medical problem in this image? | Biopsy features of a case shown to be a fibroadenoma. (A) Low power photomicrograph of a fine needle aspiration biopsy of a discrete solid mass, showing mono-layered sheets of cohesive cells in a background of bipolar cells. (B) Cohesive sheet of cells together with smaller cell clusters with a tendency to dissociation... |
PMC2359648_fig2_20869.jpg | What key item or scene is captured in this photo? | Biopsy features of a case shown to be a fibroadenoma. (A) Low power photomicrograph of a fine needle aspiration biopsy of a discrete solid mass, showing mono-layered sheets of cohesive cells in a background of bipolar cells. (B) Cohesive sheet of cells together with smaller cell clusters with a tendency to dissociation... |
PMC2359648_fig2_20870.jpg | What is the central feature of this picture? | Biopsy features of a case shown to be a fibroadenoma. (A) Low power photomicrograph of a fine needle aspiration biopsy of a discrete solid mass, showing mono-layered sheets of cohesive cells in a background of bipolar cells. (B) Cohesive sheet of cells together with smaller cell clusters with a tendency to dissociation... |
PMC2359648_fig3_20875.jpg | What is the main focus of this visual representation? | Biopsy features of a fibroadenoma accompanied by a focus of high grade DCIS. (A) Low power view of a smear showing cohesive clusters of orderly cells (arrow), together with a dispersed population of large, atypical cells (left side of picture). (B) Higher power view of a small cluster of atypical cells, showing nuclear... |
PMC2359648_fig3_20877.jpg | What is the focal point of this photograph? | Biopsy features of a fibroadenoma accompanied by a focus of high grade DCIS. (A) Low power view of a smear showing cohesive clusters of orderly cells (arrow), together with a dispersed population of large, atypical cells (left side of picture). (B) Higher power view of a small cluster of atypical cells, showing nuclear... |
PMC2359648_fig3_20876.jpg | Can you identify the primary element in this image? | Biopsy features of a fibroadenoma accompanied by a focus of high grade DCIS. (A) Low power view of a smear showing cohesive clusters of orderly cells (arrow), together with a dispersed population of large, atypical cells (left side of picture). (B) Higher power view of a small cluster of atypical cells, showing nuclear... |
PMC2359648_fig4_20873.jpg | What is the focal point of this photograph? | Biopsy features of an intraductal papilloma. (A) Low power photomicrograph showing a highly cellular smear, composed of variable sized, cohesive clusters of orderly cells, numerous bare bipolar cells and some dissociated cells. (B) Higher power view of a cellular cluster showing branching fibrovascular cores, suggestiv... |
PMC2359648_fig4_20874.jpg | Describe the main subject of this image. | Biopsy features of an intraductal papilloma. (A) Low power photomicrograph showing a highly cellular smear, composed of variable sized, cohesive clusters of orderly cells, numerous bare bipolar cells and some dissociated cells. (B) Higher power view of a cellular cluster showing branching fibrovascular cores, suggestiv... |
PMC2359648_fig4_20872.jpg | What is the main focus of this visual representation? | Biopsy features of an intraductal papilloma. (A) Low power photomicrograph showing a highly cellular smear, composed of variable sized, cohesive clusters of orderly cells, numerous bare bipolar cells and some dissociated cells. (B) Higher power view of a cellular cluster showing branching fibrovascular cores, suggestiv... |
PMC2359665_fig1_20881.jpg | What key item or scene is captured in this photo? | Cellular epigenetic heterogeneity in cancer. Immunohistochemical examination of prostate cancer tissues by an antibody against histone H3 lysine 18 acetylation reveals cell–cell differences in total levels of H3K18ac. The cells with brown nuclei are positively stained (indicated by brown block arrows) and their increas... |
PMC2359665_fig1_20879.jpg | What is the principal component of this image? | Cellular epigenetic heterogeneity in cancer. Immunohistochemical examination of prostate cancer tissues by an antibody against histone H3 lysine 18 acetylation reveals cell–cell differences in total levels of H3K18ac. The cells with brown nuclei are positively stained (indicated by brown block arrows) and their increas... |
PMC2359665_fig1_20882.jpg | Can you identify the primary element in this image? | Cellular epigenetic heterogeneity in cancer. Immunohistochemical examination of prostate cancer tissues by an antibody against histone H3 lysine 18 acetylation reveals cell–cell differences in total levels of H3K18ac. The cells with brown nuclei are positively stained (indicated by brown block arrows) and their increas... |
PMC2359665_fig1_20880.jpg | Describe the main subject of this image. | Cellular epigenetic heterogeneity in cancer. Immunohistochemical examination of prostate cancer tissues by an antibody against histone H3 lysine 18 acetylation reveals cell–cell differences in total levels of H3K18ac. The cells with brown nuclei are positively stained (indicated by brown block arrows) and their increas... |
PMC2359665_fig1_20883.jpg | Can you identify the primary element in this image? | Cellular epigenetic heterogeneity in cancer. Immunohistochemical examination of prostate cancer tissues by an antibody against histone H3 lysine 18 acetylation reveals cell–cell differences in total levels of H3K18ac. The cells with brown nuclei are positively stained (indicated by brown block arrows) and their increas... |
PMC2359759_F2_20888.jpg | What is being portrayed in this visual content? | Immunohistochemical analysis of Prox1 in normal human liver, in cirrhotic livers and in hepatocellular carcinoma. A) Double immunofluorescent labeling of HepPar1 (green), Prox1 (red) and cell nuclear counterstaining with DAPI (blue) in normal human liver shown combined. A: Arteria, B: Bile duct, V: Vena. Bars represent... |
PMC2359759_F2_20885.jpg | What is the central feature of this picture? | Immunohistochemical analysis of Prox1 in normal human liver, in cirrhotic livers and in hepatocellular carcinoma. A) Double immunofluorescent labeling of HepPar1 (green), Prox1 (red) and cell nuclear counterstaining with DAPI (blue) in normal human liver shown combined. A: Arteria, B: Bile duct, V: Vena. Bars represent... |
PMC2359759_F2_20889.jpg | What is shown in this image? | Immunohistochemical analysis of Prox1 in normal human liver, in cirrhotic livers and in hepatocellular carcinoma. A) Double immunofluorescent labeling of HepPar1 (green), Prox1 (red) and cell nuclear counterstaining with DAPI (blue) in normal human liver shown combined. A: Arteria, B: Bile duct, V: Vena. Bars represent... |
PMC2359759_F2_20886.jpg | What is the main focus of this visual representation? | Immunohistochemical analysis of Prox1 in normal human liver, in cirrhotic livers and in hepatocellular carcinoma. A) Double immunofluorescent labeling of HepPar1 (green), Prox1 (red) and cell nuclear counterstaining with DAPI (blue) in normal human liver shown combined. A: Arteria, B: Bile duct, V: Vena. Bars represent... |
PMC2359759_F2_20887.jpg | What object or scene is depicted here? | Immunohistochemical analysis of Prox1 in normal human liver, in cirrhotic livers and in hepatocellular carcinoma. A) Double immunofluorescent labeling of HepPar1 (green), Prox1 (red) and cell nuclear counterstaining with DAPI (blue) in normal human liver shown combined. A: Arteria, B: Bile duct, V: Vena. Bars represent... |
PMC2359763_F1_20891.jpg | What does this image primarily show? | CT scan demonstrating pulmonary nodules. |
PMC2359765_F2_20893.jpg | What is the focal point of this photograph? | Biopsy findings. a) Schwann cells and ganglion cells, the typical features of a ganglioneuroma, are seen in this microphotograph. Hematoxilin & Eosin 200×. b) High power view of a group of mature ganglion cells. Hematoxilin & Eosin 400×. |
PMC2359765_F2_20892.jpg | What is the core subject represented in this visual? | Biopsy findings. a) Schwann cells and ganglion cells, the typical features of a ganglioneuroma, are seen in this microphotograph. Hematoxilin & Eosin 200×. b) High power view of a group of mature ganglion cells. Hematoxilin & Eosin 400×. |
PMC2359917_fig2_20895.jpg | What is the core subject represented in this visual? | The effect of AN-7 and Dox on mitochondrial membrane potential in neonatal rat cardiomyocytes. Cardiomyocytes (6 × 105 cells well−1, 24-well plates) were grown for 72 h and then treated with 2 μM Dox for 5 h, 100 μM AN-7, 100 μM AN-88 or the combination as indicated. In the combination, the prodrug was added 1 h before... |
PMC2359917_fig2_20897.jpg | What key item or scene is captured in this photo? | The effect of AN-7 and Dox on mitochondrial membrane potential in neonatal rat cardiomyocytes. Cardiomyocytes (6 × 105 cells well−1, 24-well plates) were grown for 72 h and then treated with 2 μM Dox for 5 h, 100 μM AN-7, 100 μM AN-88 or the combination as indicated. In the combination, the prodrug was added 1 h before... |
PMC2359917_fig2_20894.jpg | What can you see in this picture? | The effect of AN-7 and Dox on mitochondrial membrane potential in neonatal rat cardiomyocytes. Cardiomyocytes (6 × 105 cells well−1, 24-well plates) were grown for 72 h and then treated with 2 μM Dox for 5 h, 100 μM AN-7, 100 μM AN-88 or the combination as indicated. In the combination, the prodrug was added 1 h before... |
PMC2359917_fig2_20900.jpg | What is the main focus of this visual representation? | The effect of AN-7 and Dox on mitochondrial membrane potential in neonatal rat cardiomyocytes. Cardiomyocytes (6 × 105 cells well−1, 24-well plates) were grown for 72 h and then treated with 2 μM Dox for 5 h, 100 μM AN-7, 100 μM AN-88 or the combination as indicated. In the combination, the prodrug was added 1 h before... |
PMC2359917_fig2_20896.jpg | What stands out most in this visual? | The effect of AN-7 and Dox on mitochondrial membrane potential in neonatal rat cardiomyocytes. Cardiomyocytes (6 × 105 cells well−1, 24-well plates) were grown for 72 h and then treated with 2 μM Dox for 5 h, 100 μM AN-7, 100 μM AN-88 or the combination as indicated. In the combination, the prodrug was added 1 h before... |
PMC2359941_fig1_20901.jpg | What key item or scene is captured in this photo? | Haematoxylin and eosin-stained section and the results of sequencing analysis in case 9. Upper and lower panels show high (× 200) and low magnification of a section, respectively. Areas indicated by white arrows were microdissected and the sequence of the BRAF gene was analysed. A heterozygous missense mutation (T1799A... |
PMC2359941_fig1_20902.jpg | What is the central feature of this picture? | Haematoxylin and eosin-stained section and the results of sequencing analysis in case 9. Upper and lower panels show high (× 200) and low magnification of a section, respectively. Areas indicated by white arrows were microdissected and the sequence of the BRAF gene was analysed. A heterozygous missense mutation (T1799A... |
PMC2359941_fig1_20903.jpg | What is the core subject represented in this visual? | Haematoxylin and eosin-stained section and the results of sequencing analysis in case 9. Upper and lower panels show high (× 200) and low magnification of a section, respectively. Areas indicated by white arrows were microdissected and the sequence of the BRAF gene was analysed. A heterozygous missense mutation (T1799A... |
PMC2359948_fig1_20911.jpg | What is the main focus of this visual representation? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20912.jpg | Can you identify the primary element in this image? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20906.jpg | What is the focal point of this photograph? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20907.jpg | What does this image primarily show? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20914.jpg | What is being portrayed in this visual content? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20909.jpg | What object or scene is depicted here? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20916.jpg | What stands out most in this visual? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20908.jpg | What is the central feature of this picture? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20917.jpg | What can you see in this picture? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359948_fig1_20913.jpg | What can you see in this picture? | (A) CD3+ infiltrating T-lymphocytes surrounding the follicular CBCL lesion. Magnification × 10. (B and C) Proliferation status of the tumour cells as determined by ki-67 staining before (B) and during (C) therapy with rituximab. Magnification × 20. (D–F) Expression status of CD20 in relapsed CBCL before (D) and during ... |
PMC2359957_fig1_20921.jpg | What stands out most in this visual? | Methylcholanthrene-induced tumours exhibit a significant enrichment of CD4+FOXP3+ Tregs. Sections of MCA-induced tumours were stained with anti-FOXP3-specific Ab and either anti-CD4 (A) or –CD8 (B) specific mAb. Single-cell suspensions of TILs, NTDLN, TDLN, spleen and blood were stained with anti-CD4-, anti-CD25- and a... |
PMC2359957_fig1_20925.jpg | What stands out most in this visual? | Methylcholanthrene-induced tumours exhibit a significant enrichment of CD4+FOXP3+ Tregs. Sections of MCA-induced tumours were stained with anti-FOXP3-specific Ab and either anti-CD4 (A) or –CD8 (B) specific mAb. Single-cell suspensions of TILs, NTDLN, TDLN, spleen and blood were stained with anti-CD4-, anti-CD25- and a... |
PMC2359957_fig1_20923.jpg | What is the central feature of this picture? | Methylcholanthrene-induced tumours exhibit a significant enrichment of CD4+FOXP3+ Tregs. Sections of MCA-induced tumours were stained with anti-FOXP3-specific Ab and either anti-CD4 (A) or –CD8 (B) specific mAb. Single-cell suspensions of TILs, NTDLN, TDLN, spleen and blood were stained with anti-CD4-, anti-CD25- and a... |
PMC2359957_fig1_20922.jpg | Can you identify the primary element in this image? | Methylcholanthrene-induced tumours exhibit a significant enrichment of CD4+FOXP3+ Tregs. Sections of MCA-induced tumours were stained with anti-FOXP3-specific Ab and either anti-CD4 (A) or –CD8 (B) specific mAb. Single-cell suspensions of TILs, NTDLN, TDLN, spleen and blood were stained with anti-CD4-, anti-CD25- and a... |
PMC2359957_fig1_20919.jpg | What is being portrayed in this visual content? | Methylcholanthrene-induced tumours exhibit a significant enrichment of CD4+FOXP3+ Tregs. Sections of MCA-induced tumours were stained with anti-FOXP3-specific Ab and either anti-CD4 (A) or –CD8 (B) specific mAb. Single-cell suspensions of TILs, NTDLN, TDLN, spleen and blood were stained with anti-CD4-, anti-CD25- and a... |
PMC2359962_fig1_20932.jpg | What key item or scene is captured in this photo? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20928.jpg | What's the most prominent thing you notice in this picture? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20926.jpg | What is the core subject represented in this visual? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20927.jpg | What is the core subject represented in this visual? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20929.jpg | What stands out most in this visual? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20930.jpg | What is the dominant medical problem in this image? | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig1_20931.jpg | Describe the main subject of this image. | Simple vascular network of tracheal mucosa used to examine effects of VEGF inhibition on normal blood vessels in adult mice. (A) Tracheal vasculature has a simple, repetitive network of arterioles, capillaries, and venules aligned with each cartilaginous ring (Baffert et al, 2004). (B–D) Confocal microscopic images of ... |
PMC2359962_fig2_20935.jpg | What is shown in this image? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20939.jpg | What can you see in this picture? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20937.jpg | What is the principal component of this image? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20941.jpg | What object or scene is depicted here? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20942.jpg | What is the core subject represented in this visual? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20934.jpg | What stands out most in this visual? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig2_20936.jpg | What key item or scene is captured in this photo? | Regression of capillaries in vasculature of normal adult mice after inhibition of VEGF signalling. (A–D) Confocal microscopic images showing capillaries in pancreatic islets (A and B) and villi of small intestine (C and D) under baseline conditions and after VEGF inhibition. After Ad-sVEGFR-1 for 14 days, endothelial c... |
PMC2359962_fig3_20943.jpg | What is shown in this image? | Reduction in endothelial fenestrations (arrowheads) after inhibition of VEGF signalling. (A and B) Transmission electron microscopic images of islet capillaries showing thin endothelium and abundant fenestrations with diaphragms under baseline conditions compared to thick endothelium, few fenestrations, and abundant ca... |
PMC2359962_fig3_20949.jpg | What is the dominant medical problem in this image? | Reduction in endothelial fenestrations (arrowheads) after inhibition of VEGF signalling. (A and B) Transmission electron microscopic images of islet capillaries showing thin endothelium and abundant fenestrations with diaphragms under baseline conditions compared to thick endothelium, few fenestrations, and abundant ca... |
PMC2359962_fig3_20947.jpg | Describe the main subject of this image. | Reduction in endothelial fenestrations (arrowheads) after inhibition of VEGF signalling. (A and B) Transmission electron microscopic images of islet capillaries showing thin endothelium and abundant fenestrations with diaphragms under baseline conditions compared to thick endothelium, few fenestrations, and abundant ca... |
PMC2359963_fig2_20952.jpg | What is the core subject represented in this visual? | Upregulation of NF-κB in H. felis infection. Expression of NF-κB (A, C) and IL-8 (B, D) in infiltrating cells at the base of gastric glands (A, B) and the stroma surrounding pre-metaplastic lesions (C, D) during H. felis infection, IL-8 staining is also present in pre-metaplastic lesions (D), magnification × 20. Sonic ... |
PMC2359963_fig2_20953.jpg | What is the central feature of this picture? | Upregulation of NF-κB in H. felis infection. Expression of NF-κB (A, C) and IL-8 (B, D) in infiltrating cells at the base of gastric glands (A, B) and the stroma surrounding pre-metaplastic lesions (C, D) during H. felis infection, IL-8 staining is also present in pre-metaplastic lesions (D), magnification × 20. Sonic ... |
PMC2359963_fig2_20955.jpg | Can you identify the primary element in this image? | Upregulation of NF-κB in H. felis infection. Expression of NF-κB (A, C) and IL-8 (B, D) in infiltrating cells at the base of gastric glands (A, B) and the stroma surrounding pre-metaplastic lesions (C, D) during H. felis infection, IL-8 staining is also present in pre-metaplastic lesions (D), magnification × 20. Sonic ... |
PMC2359963_fig2_20954.jpg | What is shown in this image? | Upregulation of NF-κB in H. felis infection. Expression of NF-κB (A, C) and IL-8 (B, D) in infiltrating cells at the base of gastric glands (A, B) and the stroma surrounding pre-metaplastic lesions (C, D) during H. felis infection, IL-8 staining is also present in pre-metaplastic lesions (D), magnification × 20. Sonic ... |
PMC2359967_fig2_20964.jpg | Describe the main subject of this image. | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20968.jpg | What object or scene is depicted here? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20966.jpg | What is the dominant medical problem in this image? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20969.jpg | What can you see in this picture? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20970.jpg | What is the dominant medical problem in this image? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20967.jpg | What object or scene is depicted here? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359967_fig2_20965.jpg | What is the main focus of this visual representation? | Expression of immunosuppressive cytokines and tolerogenic cell markers in melanoma at different stages of progression. To confirm the PCR-detected expression of mRNA for the cell markers and immunosuppressive cytokines examined, we performed IHC on sections from the same block as that used for RNA extraction. To avoid ... |
PMC2359968_fig1_20961.jpg | What is being portrayed in this visual content? | Immunohistochemical and immunofluorescence staining with L19-SIP antibody in SW1222 and LS174T xenograft-bearing mice. (A) Immunohistochemical staining of SW1222 xenograft lines with L19-SIP antibody. (B–D) Multiple digital fluorescence images of an LS174T tumour injected with Cy3-labelled L19-SIP antibody for 6 h demo... |
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