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PMC2394656_pone-0002341-g001_23232.jpg
Describe the main subject of this image.
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394656_pone-0002341-g001_23230.jpg
What does this image primarily show?
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394656_pone-0002341-g001_23229.jpg
What's the most prominent thing you notice in this picture?
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394656_pone-0002341-g001_23234.jpg
What's the most prominent thing you notice in this picture?
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394656_pone-0002341-g001_23233.jpg
What can you see in this picture?
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394656_pone-0002341-g001_23231.jpg
What is the principal component of this image?
Histological and immunohistochemical images representative of all self-assembled constructs (10x original magnification).(a) Gross morphology. (b) Picrosirius red stained sections. (c) Collagen II IHC sections. (d) Gross morphology profile. (e) Safranin-O/fast green stained sections. (f) Collagen I IHC sections.
PMC2394760_F1_23238.jpg
Can you identify the primary element in this image?
Histological analysis of epidermis samples. (a) Hematoxylin-eosin stained sections of entire epidermis after thermolysin incubation and removal of the dermis. (b,c,d) Epidermis fragments remaining after the first, second, and third trypsin incubation, respectively. Fragments shown in (d) are mainly composed of GKs atta...
PMC2395261_F2_23243.jpg
What is the main focus of this visual representation?
Subcellular localization of ZmTSA and ZmTSAlike fused to eGFP in maize cells. Analysis of maize mesophyll protoplasts transiently expressing ZmTSA::eGFP (A-C) or ZmTSAlike::eGFP (D-F). A, D: GFP fluorescence; B, E: Red chlorophyll autofluorescence in chloroplasts; C, F: Merged images.
PMC2395272_fig3_23249.jpg
Describe the main subject of this image.
Microscopic changes of tumour cells in patients with breast cancer treated by HIFU. (A) Untreated viable breast cancer cells. (B–D): Necrosed tumour cells represented by pyknotic nuclei (B); nuclear disruption (C); and nuclear disappearance (D). H&E staining × 400.
PMC2395272_fig3_23251.jpg
What is the main focus of this visual representation?
Microscopic changes of tumour cells in patients with breast cancer treated by HIFU. (A) Untreated viable breast cancer cells. (B–D): Necrosed tumour cells represented by pyknotic nuclei (B); nuclear disruption (C); and nuclear disappearance (D). H&E staining × 400.
PMC2395272_fig3_23248.jpg
What is the principal component of this image?
Microscopic changes of tumour cells in patients with breast cancer treated by HIFU. (A) Untreated viable breast cancer cells. (B–D): Necrosed tumour cells represented by pyknotic nuclei (B); nuclear disruption (C); and nuclear disappearance (D). H&E staining × 400.
PMC2395272_fig3_23250.jpg
What is the principal component of this image?
Microscopic changes of tumour cells in patients with breast cancer treated by HIFU. (A) Untreated viable breast cancer cells. (B–D): Necrosed tumour cells represented by pyknotic nuclei (B); nuclear disruption (C); and nuclear disappearance (D). H&E staining × 400.
PMC2395272_fig4_23252.jpg
What is being portrayed in this visual content?
Microscopic changes of tumour vascularity in patients with breast cancer treated by HIFU. (A) Untreated tumour blood vessels; (B) destruction of tumour vascularity with disruption of the endothelium and tunica media, H&E staining × 400. (C) untreated tumour vessel wall; (D) destroyed tumour blood vessels with the colla...
PMC2395272_fig4_23254.jpg
What key item or scene is captured in this photo?
Microscopic changes of tumour vascularity in patients with breast cancer treated by HIFU. (A) Untreated tumour blood vessels; (B) destruction of tumour vascularity with disruption of the endothelium and tunica media, H&E staining × 400. (C) untreated tumour vessel wall; (D) destroyed tumour blood vessels with the colla...
PMC2395272_fig4_23253.jpg
What is the central feature of this picture?
Microscopic changes of tumour vascularity in patients with breast cancer treated by HIFU. (A) Untreated tumour blood vessels; (B) destruction of tumour vascularity with disruption of the endothelium and tunica media, H&E staining × 400. (C) untreated tumour vessel wall; (D) destroyed tumour blood vessels with the colla...
PMC2395273_fig1_23247.jpg
What is the main focus of this visual representation?
(A) CT scan of a NSCLC 78 days before induction chemotherapy; (B) CT scan made 55 days after the start of induction chemotherapy with gemcitabine and cisplatin; and (C): CT scan of the same tumour 72 days after induction chemotherapy.
PMC2395276_fig2_23257.jpg
What can you see in this picture?
Microscopic and immunohistochemical findings of tumours formed in mice. (A) Microscopic findings of tumours expressing mutant Ha-ras. The tumours, irrespective of the introduced gene, c-erbB-2 or mutant Ha-ras, were shown to be composed of spindle-shaped cells with minimal nuclear atypia and less frequent mitoses. (B) ...
PMC2395278_fig1_23259.jpg
What is the core subject represented in this visual?
Representative histology of two tumours before and after xenograft on nude mice. (A) GIR in situ tumour, anaplastic oligodendroglioma morphology, haematoxylin–eosin HE staining (magnification × 200); (B) ODA-17-GIR corresponding xenograft, passage 1, dedifferentiated morphology, HE staining (× 400); (C) ROM in situ tum...
PMC2395278_fig1_23258.jpg
What is being portrayed in this visual content?
Representative histology of two tumours before and after xenograft on nude mice. (A) GIR in situ tumour, anaplastic oligodendroglioma morphology, haematoxylin–eosin HE staining (magnification × 200); (B) ODA-17-GIR corresponding xenograft, passage 1, dedifferentiated morphology, HE staining (× 400); (C) ROM in situ tum...
PMC2395278_fig1_23260.jpg
What is the core subject represented in this visual?
Representative histology of two tumours before and after xenograft on nude mice. (A) GIR in situ tumour, anaplastic oligodendroglioma morphology, haematoxylin–eosin HE staining (magnification × 200); (B) ODA-17-GIR corresponding xenograft, passage 1, dedifferentiated morphology, HE staining (× 400); (C) ROM in situ tum...
PMC2395278_fig1_23261.jpg
What is the principal component of this image?
Representative histology of two tumours before and after xenograft on nude mice. (A) GIR in situ tumour, anaplastic oligodendroglioma morphology, haematoxylin–eosin HE staining (magnification × 200); (B) ODA-17-GIR corresponding xenograft, passage 1, dedifferentiated morphology, HE staining (× 400); (C) ROM in situ tum...
PMC2395280_fig9_23262.jpg
What is the central feature of this picture?
Immunohistochemical staining of a skin biopsy. A skin biopsy taken 3 days after the administration of MDX-H210 (patient #21) was stained for macrophages and PMN. Macrophages (arrow) were stained with a CD68 antibody, and PMN (arrow) with chloroacetate esterase. A skin biopsy from the same patient taken before the start...
PMC2395288_fig2_23264.jpg
What is the central feature of this picture?
Overexpression of p53 in a well-differentiated SCC: magnification × 40.
PMC2395304_fig4_23273.jpg
What is the main focus of this visual representation?
Histopathological appearance of cell lines growing as tumours in nude mice. (A) Mammary tumour produced by PN2, showing chord-like structures (c), surrounded by spindle cells (arrows). (B) Mammary tumour produced by PN2, showing a predominant spindle cell component. (C) Mammary tumour produced by 8Neup9Ka, showing inva...
PMC2395304_fig4_23272.jpg
What is the central feature of this picture?
Histopathological appearance of cell lines growing as tumours in nude mice. (A) Mammary tumour produced by PN2, showing chord-like structures (c), surrounded by spindle cells (arrows). (B) Mammary tumour produced by PN2, showing a predominant spindle cell component. (C) Mammary tumour produced by 8Neup9Ka, showing inva...
PMC2395304_fig4_23269.jpg
What is being portrayed in this visual content?
Histopathological appearance of cell lines growing as tumours in nude mice. (A) Mammary tumour produced by PN2, showing chord-like structures (c), surrounded by spindle cells (arrows). (B) Mammary tumour produced by PN2, showing a predominant spindle cell component. (C) Mammary tumour produced by 8Neup9Ka, showing inva...
PMC2395304_fig4_23271.jpg
What is the core subject represented in this visual?
Histopathological appearance of cell lines growing as tumours in nude mice. (A) Mammary tumour produced by PN2, showing chord-like structures (c), surrounded by spindle cells (arrows). (B) Mammary tumour produced by PN2, showing a predominant spindle cell component. (C) Mammary tumour produced by 8Neup9Ka, showing inva...
PMC2395304_fig4_23274.jpg
What is shown in this image?
Histopathological appearance of cell lines growing as tumours in nude mice. (A) Mammary tumour produced by PN2, showing chord-like structures (c), surrounded by spindle cells (arrows). (B) Mammary tumour produced by PN2, showing a predominant spindle cell component. (C) Mammary tumour produced by 8Neup9Ka, showing inva...
PMC2395304_fig5_23279.jpg
Describe the main subject of this image.
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23284.jpg
What is the principal component of this image?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23276.jpg
What is shown in this image?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23278.jpg
What is the focal point of this photograph?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23282.jpg
What is shown in this image?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23286.jpg
Can you identify the primary element in this image?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23280.jpg
What is the main focus of this visual representation?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23281.jpg
What is the focal point of this photograph?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23283.jpg
What is the dominant medical problem in this image?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395304_fig5_23277.jpg
What object or scene is depicted here?
Immunocytochemical staining of mammary tumours and metastases produced in nude mice. (A) Mammary tumour produced by 8Neu, showing strong cell surface staining of carcinoma cells for Neu (arrows). (B) Mammary tumour produced by PN2, showing strong staining of chords of epithelial cells for Neu (e), the stromal fibroblas...
PMC2395306_fig3_23268.jpg
What is the core subject represented in this visual?
Evaluation of tumour angiogenesis. Identification of external border of tumour growth at × 40 (A) and × 100 (B) magnification field: I (desmoplastic stroma), II (infiltration zone), and III (tumour). At × 250 magnification field (C and D), it is possible to appreciate the differences in the degree of MVD between tumour...
PMC2395306_fig3_23265.jpg
What's the most prominent thing you notice in this picture?
Evaluation of tumour angiogenesis. Identification of external border of tumour growth at × 40 (A) and × 100 (B) magnification field: I (desmoplastic stroma), II (infiltration zone), and III (tumour). At × 250 magnification field (C and D), it is possible to appreciate the differences in the degree of MVD between tumour...
PMC2396155_F2_23288.jpg
What is being portrayed in this visual content?
Axial computerized tomography: edematous pancreatitis, without necrosis foci, abscesses, hemorrhage, pseudocysts, associated with liquid deposits in the pararenal region.
PMC2396155_F3_23287.jpg
What is the central feature of this picture?
Skin biopsy: clusters of histiocytes with froth-like cytoplasm (hematoxiline-eosine).
PMC2396175_F4_23293.jpg
What is being portrayed in this visual content?
Prevention of focus formation by CXB, DMC, and UMC. U251 glioblastoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 3 months in the same cell culture dishes (i.e., without splitting the cell monolayers). In A., cells were treated with or without 30 μM CXB and photomicrographs (...
PMC2396175_F4_23291.jpg
Can you identify the primary element in this image?
Prevention of focus formation by CXB, DMC, and UMC. U251 glioblastoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 3 months in the same cell culture dishes (i.e., without splitting the cell monolayers). In A., cells were treated with or without 30 μM CXB and photomicrographs (...
PMC2396175_F4_23290.jpg
What is shown in this image?
Prevention of focus formation by CXB, DMC, and UMC. U251 glioblastoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 3 months in the same cell culture dishes (i.e., without splitting the cell monolayers). In A., cells were treated with or without 30 μM CXB and photomicrographs (...
PMC2396175_F7_23298.jpg
Describe the main subject of this image.
Lower cell densities in the presence of CXB, DMC, and UMC. MIA-PaCa-2 (COX-2 negative) and Bx-PC-3 (high COX-2 expression) pancreatic carcinoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 2 months in the same cell culture dishes (i.e., without splitting the cell monolayers). ...
PMC2396175_F7_23296.jpg
What object or scene is depicted here?
Lower cell densities in the presence of CXB, DMC, and UMC. MIA-PaCa-2 (COX-2 negative) and Bx-PC-3 (high COX-2 expression) pancreatic carcinoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 2 months in the same cell culture dishes (i.e., without splitting the cell monolayers). ...
PMC2396175_F7_23299.jpg
What can you see in this picture?
Lower cell densities in the presence of CXB, DMC, and UMC. MIA-PaCa-2 (COX-2 negative) and Bx-PC-3 (high COX-2 expression) pancreatic carcinoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 2 months in the same cell culture dishes (i.e., without splitting the cell monolayers). ...
PMC2396175_F7_23297.jpg
What is the principal component of this image?
Lower cell densities in the presence of CXB, DMC, and UMC. MIA-PaCa-2 (COX-2 negative) and Bx-PC-3 (high COX-2 expression) pancreatic carcinoma cells were continuously exposed to various concentrations of CXB, DMC, or UMC for up to 2 months in the same cell culture dishes (i.e., without splitting the cell monolayers). ...
PMC2396177_F2_23304.jpg
What is the dominant medical problem in this image?
Immunohistochemical staining for macrophages (CD68) and T-lymphocyte subsets (CD5, CD4, and CD8) in lung tissue biopsy. (a) Lung tissue with well-formed granulomas, hematoxylin and eosin stain, 200× magnification. (b) Anti-CD68 (brown) and anti-CD5 (red) immunostaining, 400× magnification. (c) Anti-CD68 (brown) and ant...
PMC2396177_F2_23301.jpg
What is the main focus of this visual representation?
Immunohistochemical staining for macrophages (CD68) and T-lymphocyte subsets (CD5, CD4, and CD8) in lung tissue biopsy. (a) Lung tissue with well-formed granulomas, hematoxylin and eosin stain, 200× magnification. (b) Anti-CD68 (brown) and anti-CD5 (red) immunostaining, 400× magnification. (c) Anti-CD68 (brown) and ant...
PMC2396177_F2_23302.jpg
What's the most prominent thing you notice in this picture?
Immunohistochemical staining for macrophages (CD68) and T-lymphocyte subsets (CD5, CD4, and CD8) in lung tissue biopsy. (a) Lung tissue with well-formed granulomas, hematoxylin and eosin stain, 200× magnification. (b) Anti-CD68 (brown) and anti-CD5 (red) immunostaining, 400× magnification. (c) Anti-CD68 (brown) and ant...
PMC2396177_F3_23295.jpg
What is the central feature of this picture?
Immunohistochemical staining for tumor necrosis factor-α in lung tissue biopsy. (a) Anti-tumor necrosis factor-α immunostaining (brown), 200× magnification. (b) Isotype control antibody immunostaining (negative control) for anti-tumor necrosis factor-α, 200× magnification.
PMC2396281_pone-0002352-g002_23306.jpg
What is being portrayed in this visual content?
Agrobacteria recovered from the injected mice direct GFP expression in plant cells.GFP accumulation in leaf sectors co-injected with agrobacteria carrying the CaMV 35S promoter-based binary construct and isolated from mouse blood was determined 3 dpi. Control, agrobacteria used for mouse injection.
PMC2396283_pone-0002342-g006_23307.jpg
What key item or scene is captured in this photo?
Hyperoxia in a tent at 4450 m. on the Tibetan plateau, near Korzok village in Ladakh, India.The subjects were exposed to hyperoxia for 1 hour. Note the venous catheters in place on the forearms to allow the drawing of blood for the post hyperoxia samples. This maneuver resulted in significant changes in gene expression...
PMC2396292_pone-0002366-g005_23310.jpg
What can you see in this picture?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396292_pone-0002366-g005_23313.jpg
What is the main focus of this visual representation?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396292_pone-0002366-g005_23315.jpg
What is the principal component of this image?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396292_pone-0002366-g005_23314.jpg
What is the principal component of this image?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396292_pone-0002366-g005_23312.jpg
What is shown in this image?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396292_pone-0002366-g005_23308.jpg
What key item or scene is captured in this photo?
Newly generated cells 1–2 months after their genesis in the cerebellar cortex of peripuberal rabbits.Countings of BrdU+ cells in the cerebellar cortex at 5, 15, and 65 days after injection (A) reveal a marked drop during the first two weeks followed by a relative stabilization during the subsequent months (F = 19,01, p...
PMC2396520_pone-0002371-g002_23324.jpg
Describe the main subject of this image.
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23326.jpg
Describe the main subject of this image.
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23322.jpg
What object or scene is depicted here?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23327.jpg
What is the dominant medical problem in this image?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23319.jpg
What is the main focus of this visual representation?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23328.jpg
What is the dominant medical problem in this image?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23320.jpg
What is the focal point of this photograph?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23317.jpg
What is being portrayed in this visual content?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396520_pone-0002371-g002_23318.jpg
What is shown in this image?
Antitumor effects of mAb CDRs.A. In vitro cytotoxic effects of C7/pc42 H2 in human melanoma cell lineages; B. DNA degradation in B16F10-Nex2 cells induced by CDRs C7/pc42 H2 and HuA L1; S-C7H2 and S-HuaL1, scrambled peptides; STD, 1 Kb Plus DNA Ladder, Invitrogen; C. Apoptotic response of HL-60 cells to peptides C7/pc4...
PMC2396598_F1_23329.jpg
What is being portrayed in this visual content?
Negative control, nm23 protein immunohistochmical staining in normal breast tissue, showing absent staining (×200).
PMC2396598_F4_23330.jpg
What is the central feature of this picture?
nm23 protein immunohistochmical staining in infiltrating ductal carcinoma, showing Strong nuclear and cytoplasmic staining (×200).
PMC2396625_F1_23332.jpg
What is the core subject represented in this visual?
CMR images in the acute (left) and convalescent (right) phase of myocarditis. Upper left: SSFP-cine images showing increased LV mass compared to follow-up (upper right). Lower left: T2-weighted STIR images with higher signal intensity of myocardium compared to follow-up (lower right). [SSFP: steady-state free precessio...
PMC2396625_F1_23335.jpg
What is the principal component of this image?
CMR images in the acute (left) and convalescent (right) phase of myocarditis. Upper left: SSFP-cine images showing increased LV mass compared to follow-up (upper right). Lower left: T2-weighted STIR images with higher signal intensity of myocardium compared to follow-up (lower right). [SSFP: steady-state free precessio...
PMC2396626_F1_23331.jpg
What can you see in this picture?
A nerve root and its supplying artery of a normal rabbit are represented, which were reconstructed three dimensionally by using consecutive sections of the same artery specimen. The reconstructed artery is accepted as a cylinder, and its surface area is calculated as: S = 2∏rh; the endothelial cell density was calculat...
PMC2396649_F2_23338.jpg
What is the main focus of this visual representation?
A representative microscopic picture of a section of the myofibroblastoma. This is a high-power view on the right side of the section.
PMC2396649_F2_23337.jpg
What stands out most in this visual?
A representative microscopic picture of a section of the myofibroblastoma. This is a high-power view on the right side of the section.
PMC2396650_F1_23336.jpg
What is the focal point of this photograph?
Computed tomography scan of the brain at admission.
PMC2396650_F2_23339.jpg
What is the principal component of this image?
Computed tomography scan of the brain 72 hours after admission.
PMC2396652_F1_23340.jpg
What is shown in this image?
Liver biopsy image: bile thrombi (brown pigment) in dilated canaliculi is seen resulting in canalicular stasis.
PMC2396653_F1_23341.jpg
What's the most prominent thing you notice in this picture?
X-ray of the abdomen illustrating the migrated pacemaker generator in the pelvis.
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What does this image primarily show?
X-ray depicting the endocardial pacemaker inserted through the right subclavian vein.
PMC2396656_F1_23344.jpg
Can you identify the primary element in this image?
A computed tomography scan showing a thickening of the entire bladder wall with no predominant location, such as the bladder dome.
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What is the focal point of this photograph?
Histology of a nephrogenic adenoma. Papillary and tubular growth pattern of nephrogenic adenoma is shown, partly with small cysts with eosinophilic material. This histological picture was found throughout the entire urothelium of the cystectomy specimens (approximately 50% of the urothelial surface of the bladder). Hem...
PMC2396656_F2_23345.jpg
What object or scene is depicted here?
Histology of a nephrogenic adenoma. Papillary and tubular growth pattern of nephrogenic adenoma is shown, partly with small cysts with eosinophilic material. This histological picture was found throughout the entire urothelium of the cystectomy specimens (approximately 50% of the urothelial surface of the bladder). Hem...
PMC2396657_F1_23347.jpg
What stands out most in this visual?
Contrast-enhanced helical CT scan. This scan demonstrates the heterogeneous enhancement of a large tumour of the head of the pancreas, in contact with the superior mesenteric vein (SMV), without signs of infiltration or encasement of the vein, or the superior mesenteric artery (SMA).
PMC2397387_F1_23358.jpg
What is the principal component of this image?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23354.jpg
Describe the main subject of this image.
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23355.jpg
What is the focal point of this photograph?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23352.jpg
What object or scene is depicted here?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23353.jpg
What does this image primarily show?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23362.jpg
What is the core subject represented in this visual?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23356.jpg
What is the principal component of this image?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397387_F1_23350.jpg
What key item or scene is captured in this photo?
Straw blood cells in air and in solution. Straw cells originating from mouse, human and other animals. A. Straw cells derived from mouse epithelia, lymphocyte, liver and lung cells. B Human filamentous straw cells, C. Human smooth straw cells, D. Pig lung straw cells, E. Straw cells in solution; visible dark dots have ...
PMC2397405_F1_23363.jpg
What is the principal component of this image?
Lateral fluoroscopy after interventional closure of ASD: Contrast media is injected in the IVC showing the right atrium. Amplatzer Occluder in position of former ASD bracing from aortic root (asterisk). T: transesophageal probe; IVC: inferior vena cava; RA: right atrium.
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What key item or scene is captured in this photo?
Ultrastructural evidence of myelinopathy in 5-FU-treated animals. Electron micrographs were taken from the midline transverse sections of the CC (cross-sections of the axons). (a) A representative image from a sham-treated control animal, showing normal myelinated axons; (b-f) representative images from a 5-FU-treated ...
PMC2397490_F9_23369.jpg
What is shown in this image?
Ultrastructural evidence of myelinopathy in 5-FU-treated animals. Electron micrographs were taken from the midline transverse sections of the CC (cross-sections of the axons). (a) A representative image from a sham-treated control animal, showing normal myelinated axons; (b-f) representative images from a 5-FU-treated ...
PMC2397490_F9_23368.jpg
What is the central feature of this picture?
Ultrastructural evidence of myelinopathy in 5-FU-treated animals. Electron micrographs were taken from the midline transverse sections of the CC (cross-sections of the axons). (a) A representative image from a sham-treated control animal, showing normal myelinated axons; (b-f) representative images from a 5-FU-treated ...
PMC2397490_F9_23365.jpg
Describe the main subject of this image.
Ultrastructural evidence of myelinopathy in 5-FU-treated animals. Electron micrographs were taken from the midline transverse sections of the CC (cross-sections of the axons). (a) A representative image from a sham-treated control animal, showing normal myelinated axons; (b-f) representative images from a 5-FU-treated ...
PMC2397490_F9_23366.jpg
What can you see in this picture?
Ultrastructural evidence of myelinopathy in 5-FU-treated animals. Electron micrographs were taken from the midline transverse sections of the CC (cross-sections of the axons). (a) A representative image from a sham-treated control animal, showing normal myelinated axons; (b-f) representative images from a 5-FU-treated ...