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PMC2503985_F4_26504.jpg | What is the main focus of this visual representation? | Images of the immunohistochemical assays: von Willebrand factor on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days, and to control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F4_26506.jpg | What does this image primarily show? | Images of the immunohistochemical assays: von Willebrand factor on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days, and to control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F4_26502.jpg | What is the principal component of this image? | Images of the immunohistochemical assays: von Willebrand factor on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days, and to control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F5_26507.jpg | What is the dominant medical problem in this image? | Images of the immunohistochemical assays: fibronectin on endothelial cells on titanium after (A) 24 hours, (B) 7 days and (C) 14 days and on control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F5_26512.jpg | What is being portrayed in this visual content? | Images of the immunohistochemical assays: fibronectin on endothelial cells on titanium after (A) 24 hours, (B) 7 days and (C) 14 days and on control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F5_26509.jpg | What is the central feature of this picture? | Images of the immunohistochemical assays: fibronectin on endothelial cells on titanium after (A) 24 hours, (B) 7 days and (C) 14 days and on control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F5_26511.jpg | What is being portrayed in this visual content? | Images of the immunohistochemical assays: fibronectin on endothelial cells on titanium after (A) 24 hours, (B) 7 days and (C) 14 days and on control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F5_26508.jpg | What can you see in this picture? | Images of the immunohistochemical assays: fibronectin on endothelial cells on titanium after (A) 24 hours, (B) 7 days and (C) 14 days and on control surface after (D) 24 hours, (E) 7 days and (F) 14 days. |
PMC2503985_F7_26528.jpg | What is the core subject represented in this visual? | Images of the immunohistochemical assays: α(v)β3 integrin expression on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days and to control surface (D). |
PMC2503985_F7_26525.jpg | What is the core subject represented in this visual? | Images of the immunohistochemical assays: α(v)β3 integrin expression on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days and to control surface (D). |
PMC2503985_F7_26527.jpg | What is shown in this image? | Images of the immunohistochemical assays: α(v)β3 integrin expression on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days and to control surface (D). |
PMC2503985_F7_26526.jpg | What is the main focus of this visual representation? | Images of the immunohistochemical assays: α(v)β3 integrin expression on endothelial cells attached to titanium after (A) 24 hours, (B) 7 days and (C) 14 days and to control surface (D). |
PMC2503992_F1_26529.jpg | What object or scene is depicted here? | Abdominal ultrasound. A distended, thick-walled gallbladder with no gallstones and a cuff of pericholecystic fluid were revealed. |
PMC2503992_F1_26530.jpg | What is the dominant medical problem in this image? | Abdominal ultrasound. A distended, thick-walled gallbladder with no gallstones and a cuff of pericholecystic fluid were revealed. |
PMC2503992_F2_26531.jpg | What is the principal component of this image? | Abdominal computed tomography scan. Focal thickening of gallbladder neck, a hugely distended and inflamed gallbladder as well as fluid in the anterior hepatic space (as indicated by the arrow) can be seen. |
PMC2503996_F2_26533.jpg | What object or scene is depicted here? | Punch biopsy of a skin lesion showing neutrophilic infiltration in the dermis, with no evidence of vasculitis. |
PMC2503997_F1_26532.jpg | What stands out most in this visual? | Ultrasonography showing free air bubbles in the hepatic blood vessels. |
PMC2503997_F2_26536.jpg | What can you see in this picture? | Macroscopic, histological and ultrastructural assessment of small intestine tissue. (a) Macroscopic picture of the oedematous intestinal wall with multiple submucosal and subserosal cysts. (b) Histological picture of the intestinal mucosa with areactive necrosis. (c) Gram stain of cysts with large rod-shaped bacteria. ... |
PMC2503997_F2_26537.jpg | What is the core subject represented in this visual? | Macroscopic, histological and ultrastructural assessment of small intestine tissue. (a) Macroscopic picture of the oedematous intestinal wall with multiple submucosal and subserosal cysts. (b) Histological picture of the intestinal mucosa with areactive necrosis. (c) Gram stain of cysts with large rod-shaped bacteria. ... |
PMC2503997_F2_26534.jpg | What stands out most in this visual? | Macroscopic, histological and ultrastructural assessment of small intestine tissue. (a) Macroscopic picture of the oedematous intestinal wall with multiple submucosal and subserosal cysts. (b) Histological picture of the intestinal mucosa with areactive necrosis. (c) Gram stain of cysts with large rod-shaped bacteria. ... |
PMC2504488_pbio-0060194-g001_26544.jpg | What does this image primarily show? | RBR1 Interacts with MSI1(A) Pull-down assay testing for interaction between Arabidopsis MSI1 and RBR1. The full-length RBR1 protein, labeled with [35S] methionine, was incubated with GST-MSI1 protein bound to agarose beads (GST MSI). As a negative control, the labeled protein was incubated with GST only, bound to agaro... |
PMC2504488_pbio-0060194-g001_26542.jpg | What is shown in this image? | RBR1 Interacts with MSI1(A) Pull-down assay testing for interaction between Arabidopsis MSI1 and RBR1. The full-length RBR1 protein, labeled with [35S] methionine, was incubated with GST-MSI1 protein bound to agarose beads (GST MSI). As a negative control, the labeled protein was incubated with GST only, bound to agaro... |
PMC2504488_pbio-0060194-g001_26545.jpg | What is the principal component of this image? | RBR1 Interacts with MSI1(A) Pull-down assay testing for interaction between Arabidopsis MSI1 and RBR1. The full-length RBR1 protein, labeled with [35S] methionine, was incubated with GST-MSI1 protein bound to agarose beads (GST MSI). As a negative control, the labeled protein was incubated with GST only, bound to agaro... |
PMC2504488_pbio-0060194-g001_26543.jpg | Can you identify the primary element in this image? | RBR1 Interacts with MSI1(A) Pull-down assay testing for interaction between Arabidopsis MSI1 and RBR1. The full-length RBR1 protein, labeled with [35S] methionine, was incubated with GST-MSI1 protein bound to agarose beads (GST MSI). As a negative control, the labeled protein was incubated with GST only, bound to agaro... |
PMC2504488_pbio-0060194-g001_26538.jpg | What does this image primarily show? | RBR1 Interacts with MSI1(A) Pull-down assay testing for interaction between Arabidopsis MSI1 and RBR1. The full-length RBR1 protein, labeled with [35S] methionine, was incubated with GST-MSI1 protein bound to agarose beads (GST MSI). As a negative control, the labeled protein was incubated with GST only, bound to agaro... |
PMC2507705_F3_26547.jpg | What is the principal component of this image? | Immunochemistry on paraffin section (4 μm), Ki-67 positive cells in the Rathke pouch and surrounding mesenchyme, but not in the basal epithelial cones, S = stomatodeum, 20×. |
PMC2507705_F3_26548.jpg | What's the most prominent thing you notice in this picture? | Immunochemistry on paraffin section (4 μm), Ki-67 positive cells in the Rathke pouch and surrounding mesenchyme, but not in the basal epithelial cones, S = stomatodeum, 20×. |
PMC2507705_F4_26549.jpg | What is the principal component of this image? | Immunihistochemistry on paraffin section (4 μm) using antibody against active caspase-3 visualizes apoptotic events in the basal epithelial cones of the Rathke pouch (arrows), S = stomatodeum, 20×. |
PMC2507706_F2_26551.jpg | What is the core subject represented in this visual? | Malignant pleural mesothelioma of epithelial type. Epithelial MPM derives from the mesothelial cells and consists of glands and tubules that resemble adenocarcinoma. Large spherical cells are arranged in solid masses and columns mostly within lymphatics. There may also be glandular formation as demonstrated in this pho... |
PMC2507707_F1_26553.jpg | What is being portrayed in this visual content? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26562.jpg | What is the dominant medical problem in this image? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26560.jpg | What is the focal point of this photograph? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26563.jpg | What is being portrayed in this visual content? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26554.jpg | What is the main focus of this visual representation? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26555.jpg | What key item or scene is captured in this photo? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26565.jpg | Can you identify the primary element in this image? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26558.jpg | Describe the main subject of this image. | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26556.jpg | What is the main focus of this visual representation? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26561.jpg | What object or scene is depicted here? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26566.jpg | What is the dominant medical problem in this image? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2507707_F1_26564.jpg | What stands out most in this visual? | Surface morphology in relation to storage media (SEM images of tested materials at 500×–1000× magnification). |
PMC2515092_F1_26569.jpg | What's the most prominent thing you notice in this picture? | sagittal T1 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F1_26567.jpg | What is shown in this image? | sagittal T1 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F1_26568.jpg | What can you see in this picture? | sagittal T1 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F2_26572.jpg | What is the core subject represented in this visual? | sagittal T2 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F2_26571.jpg | What is the central feature of this picture? | sagittal T2 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F2_26570.jpg | What can you see in this picture? | sagittal T2 MRI showing diskitis and vertebral signal changes suggestive of osteomyelitis |
PMC2515092_F4_26574.jpg | What is the main focus of this visual representation? | Axial T2 MRI images showing the above lesions |
PMC2515092_F7_26575.jpg | What is the central feature of this picture? | photomicrograph of C. tropicalis at a higher magnification |
PMC2515219_pone-0002998-g008_26584.jpg | What's the most prominent thing you notice in this picture? | Kidney pathology at 4 days post HgCl2 administration.Sections of renal tissue stained with hematoxylin & eosin (magnificationX20). OC–outer cortex, IC–inner cortex. Note intratubular debris containing remnants of damaged tubular epithelial cells (arrows). Circles encompass tubuli lined by necrotic epithelial cells. Not... |
PMC2515219_pone-0002998-g008_26583.jpg | What is the main focus of this visual representation? | Kidney pathology at 4 days post HgCl2 administration.Sections of renal tissue stained with hematoxylin & eosin (magnificationX20). OC–outer cortex, IC–inner cortex. Note intratubular debris containing remnants of damaged tubular epithelial cells (arrows). Circles encompass tubuli lined by necrotic epithelial cells. Not... |
PMC2515219_pone-0002998-g008_26579.jpg | What is being portrayed in this visual content? | Kidney pathology at 4 days post HgCl2 administration.Sections of renal tissue stained with hematoxylin & eosin (magnificationX20). OC–outer cortex, IC–inner cortex. Note intratubular debris containing remnants of damaged tubular epithelial cells (arrows). Circles encompass tubuli lined by necrotic epithelial cells. Not... |
PMC2515219_pone-0002998-g008_26582.jpg | What is the central feature of this picture? | Kidney pathology at 4 days post HgCl2 administration.Sections of renal tissue stained with hematoxylin & eosin (magnificationX20). OC–outer cortex, IC–inner cortex. Note intratubular debris containing remnants of damaged tubular epithelial cells (arrows). Circles encompass tubuli lined by necrotic epithelial cells. Not... |
PMC2515219_pone-0002998-g012_26578.jpg | What is the principal component of this image? | Upregulation of Hspc/70.Hsp/c70 viewed by confocal microscopy at magnification x60 and zoom x2. Left–VLP-treated mice. Right–Sham mice. IgG-negative control. For clarification, both images were identically adjusted using Adobe Photoshop CS2, by ‘autocolor’ adjustment. |
PMC2515219_pone-0002998-g012_26577.jpg | What key item or scene is captured in this photo? | Upregulation of Hspc/70.Hsp/c70 viewed by confocal microscopy at magnification x60 and zoom x2. Left–VLP-treated mice. Right–Sham mice. IgG-negative control. For clarification, both images were identically adjusted using Adobe Photoshop CS2, by ‘autocolor’ adjustment. |
PMC2515294_F2_26585.jpg | What is the core subject represented in this visual? | Radiography of kyphoscoliosis in alpha-mannosidosis before and after orthopedic correction. A. Kyphoscoliosis with skeletal abnormalities of all vertebrae. B. Orthopedic correction of kyphosis. |
PMC2515294_F2_26586.jpg | What does this image primarily show? | Radiography of kyphoscoliosis in alpha-mannosidosis before and after orthopedic correction. A. Kyphoscoliosis with skeletal abnormalities of all vertebrae. B. Orthopedic correction of kyphosis. |
PMC2515298_F3_26588.jpg | What is the principal component of this image? | Interface of the ImageLab/Virtual Microscope software: Real-time browsing, thumbnail window for navigation and zoom in application. |
PMC2515298_F3_26589.jpg | Can you identify the primary element in this image? | Interface of the ImageLab/Virtual Microscope software: Real-time browsing, thumbnail window for navigation and zoom in application. |
PMC2515298_F3_26590.jpg | Can you identify the primary element in this image? | Interface of the ImageLab/Virtual Microscope software: Real-time browsing, thumbnail window for navigation and zoom in application. |
PMC2515301_F1_26592.jpg | Can you identify the primary element in this image? | Intraoral finding after initial biopsy: Exophytic and endophytic growing tumour of the left buccal mucosa (3 × 2 × 1.5 cm3) with indiscernible borders. |
PMC2515301_F3_26593.jpg | What is the core subject represented in this visual? | Computerized tomography (CT) with contrast medium (CM): Axial image of the head and neck: Tumour (4 × 5 cm2) of the left buccal soft tissues with central necrotic and partly calcified components and resorption of the left mandible. |
PMC2515304_F3_26595.jpg | What is the core subject represented in this visual? | Single photon emission computed tomography (SPECT) images from a depressed patient showing characteristic hypofrontality relative to a healthy control subject[82]. |
PMC2515304_F4_26598.jpg | Can you identify the primary element in this image? | Positron emission tomography (PET) images of cerebral blood flow changes during transient induced sadness in healthy controls (left); pre deep brain stimulation (DBS) in depressed patients (centre); and 3-month post DBS in treatment responsive patients (right). Hyperactivity in Cg25 and hypoactivity in the dorsolateral... |
PMC2515304_F4_26599.jpg | What can you see in this picture? | Positron emission tomography (PET) images of cerebral blood flow changes during transient induced sadness in healthy controls (left); pre deep brain stimulation (DBS) in depressed patients (centre); and 3-month post DBS in treatment responsive patients (right). Hyperactivity in Cg25 and hypoactivity in the dorsolateral... |
PMC2515344_ppat-1000134-g001_26610.jpg | Describe the main subject of this image. | HIV concentration in mature MDDCs requires an intact actin cytoskeleton.(A,B) Mature DCs were plated onto coverslips, pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 30 min, washed and fixed (A) or incubated an additional hour and fixed (B). Fixed cells were stained for actin cytoskeleton (red) and nuclear DNA (bl... |
PMC2515344_ppat-1000134-g001_26604.jpg | What key item or scene is captured in this photo? | HIV concentration in mature MDDCs requires an intact actin cytoskeleton.(A,B) Mature DCs were plated onto coverslips, pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 30 min, washed and fixed (A) or incubated an additional hour and fixed (B). Fixed cells were stained for actin cytoskeleton (red) and nuclear DNA (bl... |
PMC2515344_ppat-1000134-g001_26600.jpg | What can you see in this picture? | HIV concentration in mature MDDCs requires an intact actin cytoskeleton.(A,B) Mature DCs were plated onto coverslips, pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 30 min, washed and fixed (A) or incubated an additional hour and fixed (B). Fixed cells were stained for actin cytoskeleton (red) and nuclear DNA (bl... |
PMC2515344_ppat-1000134-g001_26603.jpg | What is the main focus of this visual representation? | HIV concentration in mature MDDCs requires an intact actin cytoskeleton.(A,B) Mature DCs were plated onto coverslips, pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 30 min, washed and fixed (A) or incubated an additional hour and fixed (B). Fixed cells were stained for actin cytoskeleton (red) and nuclear DNA (bl... |
PMC2515344_ppat-1000134-g001_26602.jpg | What can you see in this picture? | HIV concentration in mature MDDCs requires an intact actin cytoskeleton.(A,B) Mature DCs were plated onto coverslips, pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 30 min, washed and fixed (A) or incubated an additional hour and fixed (B). Fixed cells were stained for actin cytoskeleton (red) and nuclear DNA (bl... |
PMC2515344_ppat-1000134-g002_26623.jpg | What does this image primarily show? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26633.jpg | What is the principal component of this image? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26627.jpg | What is the principal component of this image? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26631.jpg | What is the focal point of this photograph? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26625.jpg | What key item or scene is captured in this photo? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26628.jpg | What's the most prominent thing you notice in this picture? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g002_26629.jpg | What is the central feature of this picture? | HIV and cell-surface proteins are sequestered into a distinct subcellular compartment.(A–H) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, plated onto poly-L-Lysine coverslips, and fixed and stained for the indicated markers. (A) 3-D–rendered whole-cell volume, CD81 (red) and DNA (b... |
PMC2515344_ppat-1000134-g004_26643.jpg | What is the principal component of this image? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26636.jpg | What does this image primarily show? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26642.jpg | Can you identify the primary element in this image? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26638.jpg | What does this image primarily show? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26648.jpg | What key item or scene is captured in this photo? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26640.jpg | What is the focal point of this photograph? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26634.jpg | What is the focal point of this photograph? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26656.jpg | What does this image primarily show? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26653.jpg | What is being portrayed in this visual content? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26637.jpg | What stands out most in this visual? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26651.jpg | What's the most prominent thing you notice in this picture? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26645.jpg | What can you see in this picture? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g004_26649.jpg | What can you see in this picture? | DCs transmit individual HIV particles to T cells at the infectious synapse.(A–C) Mature MDDCs were incubated with GFP-Vpr/S15-RFP labeled HIV for 1 h at 37°C, washed, and plated onto a glass coverslip dish. GFP-Vpr (green) marks the HIV core, and S15-RFP (red) is a myristoylated fusion that marks the viral membrane pri... |
PMC2515344_ppat-1000134-g006_26616.jpg | Can you identify the primary element in this image? | Internalized HIV is accessible to surface applied HIV-specific inhibitory antibodies.(A–F) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, and cultured for 1 h at 37°C. Cells were then placed on ice and incubated for 30 min with (A–C) CD4-hIgG fusion protein or (D–F) 2G12 anti-HIV En... |
PMC2515344_ppat-1000134-g006_26613.jpg | What is the dominant medical problem in this image? | Internalized HIV is accessible to surface applied HIV-specific inhibitory antibodies.(A–F) Mature MDDCs were pulsed with HxB2 pseudotyped GFP-Vpr HIV (green) for 1 h, washed, and cultured for 1 h at 37°C. Cells were then placed on ice and incubated for 30 min with (A–C) CD4-hIgG fusion protein or (D–F) 2G12 anti-HIV En... |
PMC2515344_ppat-1000134-g007_26618.jpg | What can you see in this picture? | Internalized HIV is accessed by a surface-applied fluid phase marker.(A–C) Mature MDDCs were pulsed with HIV as in Figure 6 and incubated with fluorescent dextran (orange) at 4°C. Cells were plated onto coverslips, fixed, and stained for Actin (Red) and DNA (Blue). (A) 3-D view of the entire cell volume. (B) Same as (A... |
PMC2515344_ppat-1000134-g007_26622.jpg | Can you identify the primary element in this image? | Internalized HIV is accessed by a surface-applied fluid phase marker.(A–C) Mature MDDCs were pulsed with HIV as in Figure 6 and incubated with fluorescent dextran (orange) at 4°C. Cells were plated onto coverslips, fixed, and stained for Actin (Red) and DNA (Blue). (A) 3-D view of the entire cell volume. (B) Same as (A... |
PMC2515344_ppat-1000134-g007_26621.jpg | What key item or scene is captured in this photo? | Internalized HIV is accessed by a surface-applied fluid phase marker.(A–C) Mature MDDCs were pulsed with HIV as in Figure 6 and incubated with fluorescent dextran (orange) at 4°C. Cells were plated onto coverslips, fixed, and stained for Actin (Red) and DNA (Blue). (A) 3-D view of the entire cell volume. (B) Same as (A... |
PMC2515635_pone-0002985-g001_26662.jpg | What is the core subject represented in this visual? | Progression of pulmonary disease in chest radiographs from adult (35-year-old male, Panels A day 6 and B day 23 of illness) and pediatric (6-year-old male, Panels C day 6 and D day 14 of illness) H5N1 cases. |
PMC2515635_pone-0002985-g001_26663.jpg | What is the central feature of this picture? | Progression of pulmonary disease in chest radiographs from adult (35-year-old male, Panels A day 6 and B day 23 of illness) and pediatric (6-year-old male, Panels C day 6 and D day 14 of illness) H5N1 cases. |
PMC2515635_pone-0002985-g001_26661.jpg | What does this image primarily show? | Progression of pulmonary disease in chest radiographs from adult (35-year-old male, Panels A day 6 and B day 23 of illness) and pediatric (6-year-old male, Panels C day 6 and D day 14 of illness) H5N1 cases. |
PMC2515637_pone-0003032-g004_26665.jpg | What is the focal point of this photograph? | New bone formation in (a) rats and (b) rabbits.(a) Polymeric-DBM 3D scaffolds were implanted for 4 weeks intramuscularly in rats and new bone (arrows) was formed in direct apposition of DBM. (b) When implatend in ulna defects, these scaffolds repaired the defect in 6 weeks with re-establishment of bone marrow (thin bla... |
PMC2515643_pone-0003033-g002_26668.jpg | What's the most prominent thing you notice in this picture? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
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