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PMC2515643_pone-0003033-g002_26672.jpg | What is being portrayed in this visual content? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26673.jpg | What is the core subject represented in this visual? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26670.jpg | What's the most prominent thing you notice in this picture? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26666.jpg | What does this image primarily show? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26671.jpg | What is the main focus of this visual representation? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26669.jpg | What is the focal point of this photograph? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515643_pone-0003033-g002_26667.jpg | What is the central feature of this picture? | TLOs are formed in various organs of AID−/− mice.The tissue samples were obtained from 12-month-old AID−/− or AID+/+ mice, and were subjected to histological examination after H–E staining. Asterisks represent TLOs. Scale bars: 100 µm. |
PMC2515833_F1_26674.jpg | Describe the main subject of this image. | TEE image 1 of the first patient. Color Doppler imaging depicts the interatrial shunting (arrow). LA – Left Atrium; RA – Right Atrium. |
PMC2515841_F1_26675.jpg | Can you identify the primary element in this image? | Cutaneous Kaposi sarcoma lesion, plaque stage (H&E stain; original magnification ×100). |
PMC2515841_F2_26677.jpg | What is the principal component of this image? | Higher power magnification of Kaposi sarcoma lesion showing infiltrating plump spindled tumor cells admixed with blood vessels and a sparse mononuclear inflammatory infiltrate (H&E stain; original magnification ×400). |
PMC2515841_F3_26676.jpg | What is the core subject represented in this visual? | K5 immunoreactivity is shown in occasional tumor cells (arrows) in this KS flare lesion (K5 immunohistochemical stain; original magnification ×400). |
PMC2515846_F2_26678.jpg | What is the dominant medical problem in this image? | Contrast-enhanced CT revealed a large tumor in the entire abdomen and showed septum in the cystic tumor. |
PMC2515846_F3_26679.jpg | What is the principal component of this image? | MRI detected a thick septum in the tumor center, which divided the tumor into the upper and lower regions. T2-weighted imaging showed coexistence of areas with high and low signal intensity. (a) coronal T2-weight imaging (b) sagittal T1-weight imaging. |
PMC2515846_F3_26680.jpg | What object or scene is depicted here? | MRI detected a thick septum in the tumor center, which divided the tumor into the upper and lower regions. T2-weighted imaging showed coexistence of areas with high and low signal intensity. (a) coronal T2-weight imaging (b) sagittal T1-weight imaging. |
PMC2515846_F6_26681.jpg | What is the focal point of this photograph? | Microscopic findings of the resected specimen. Histologically, the tumor mainly consisted of spindle cells, which showed fascicular growth. Immunostaining demonstrated c-kit positive, partial α-SMA positive, and S-100 protein negative. |
PMC2515846_F6_26682.jpg | What is the principal component of this image? | Microscopic findings of the resected specimen. Histologically, the tumor mainly consisted of spindle cells, which showed fascicular growth. Immunostaining demonstrated c-kit positive, partial α-SMA positive, and S-100 protein negative. |
PMC2515846_F6_26684.jpg | What is the main focus of this visual representation? | Microscopic findings of the resected specimen. Histologically, the tumor mainly consisted of spindle cells, which showed fascicular growth. Immunostaining demonstrated c-kit positive, partial α-SMA positive, and S-100 protein negative. |
PMC2516172_pone-0003046-g004_26685.jpg | What is the principal component of this image? | Neuroimaging results.(a) Differential tactile activation maps contrasting the blindfold and non blindfold groups are shown for each fMRI session of the study. (b) A region of interest (ROI) was defined by the area of occipital activation found on day 5 in the group maps. The average differential tactile activity betwee... |
PMC2516172_pone-0003046-g004_26686.jpg | Can you identify the primary element in this image? | Neuroimaging results.(a) Differential tactile activation maps contrasting the blindfold and non blindfold groups are shown for each fMRI session of the study. (b) A region of interest (ROI) was defined by the area of occipital activation found on day 5 in the group maps. The average differential tactile activity betwee... |
PMC2516326_pone-0003035-g003_26690.jpg | What is the focal point of this photograph? | HE staining shows lymphoid cells (arrows) in the kidney tissue of the monkey #53.Scale bar corresponds to 500 µm. The magnification shows a damaged tubulus surrounded by inflammatory cells. |
PMC2516326_pone-0003035-g003_26689.jpg | What stands out most in this visual? | HE staining shows lymphoid cells (arrows) in the kidney tissue of the monkey #53.Scale bar corresponds to 500 µm. The magnification shows a damaged tubulus surrounded by inflammatory cells. |
PMC2516509_F2_26691.jpg | What can you see in this picture? | Case no 2, radiograph at 6 months, showing displacement. |
PMC2516513_F4_26697.jpg | What does this image primarily show? | Confocal microscopy images of tight junctions in HUVEC. (A) normal ZO-1 in untreated control HUVEC (B) disrupted ZO-1 in VPF/VEGF (10 ng/ml) treated HUVEC (C) dopamine (10 μM) + VPF/VEGF (10 ng/ml) treated HUVEC shows that pre-treatment with dopamine inhibits the ZO-1 disrupting property of VPF/VEGF (D) quinpirole (10 ... |
PMC2516513_F4_26698.jpg | What object or scene is depicted here? | Confocal microscopy images of tight junctions in HUVEC. (A) normal ZO-1 in untreated control HUVEC (B) disrupted ZO-1 in VPF/VEGF (10 ng/ml) treated HUVEC (C) dopamine (10 μM) + VPF/VEGF (10 ng/ml) treated HUVEC shows that pre-treatment with dopamine inhibits the ZO-1 disrupting property of VPF/VEGF (D) quinpirole (10 ... |
PMC2516513_F4_26696.jpg | What is being portrayed in this visual content? | Confocal microscopy images of tight junctions in HUVEC. (A) normal ZO-1 in untreated control HUVEC (B) disrupted ZO-1 in VPF/VEGF (10 ng/ml) treated HUVEC (C) dopamine (10 μM) + VPF/VEGF (10 ng/ml) treated HUVEC shows that pre-treatment with dopamine inhibits the ZO-1 disrupting property of VPF/VEGF (D) quinpirole (10 ... |
PMC2516513_F4_26695.jpg | What is the main focus of this visual representation? | Confocal microscopy images of tight junctions in HUVEC. (A) normal ZO-1 in untreated control HUVEC (B) disrupted ZO-1 in VPF/VEGF (10 ng/ml) treated HUVEC (C) dopamine (10 μM) + VPF/VEGF (10 ng/ml) treated HUVEC shows that pre-treatment with dopamine inhibits the ZO-1 disrupting property of VPF/VEGF (D) quinpirole (10 ... |
PMC2516524_F1_26700.jpg | What key item or scene is captured in this photo? | Magnetic resonance imaging showing a haemangioma located in the femoral inter-condylar notch. |
PMC2516525_F2_26701.jpg | What is the central feature of this picture? | Scintigraphy of the chest. 3 hours after inlìjection planar antero-posterior view demonstrated diffuse spots of hyperfixation in the right humeral head and acromion, medial right clavicle, sternum and ribs. Other views confirmed bone localization of metastases on more sites. |
PMC2516530_pone-0003061-g004_26704.jpg | What is the main focus of this visual representation? | Photograph of seedlings showing anthocyanin accumulation.Seedlings were grown on 6% sucrose medium for 15 days. The transgenic line numbers are indicated below the photograph. 2x is diploid, 4x tetraploid. |
PMC2516530_pone-0003061-g004_26705.jpg | What is shown in this image? | Photograph of seedlings showing anthocyanin accumulation.Seedlings were grown on 6% sucrose medium for 15 days. The transgenic line numbers are indicated below the photograph. 2x is diploid, 4x tetraploid. |
PMC2516530_pone-0003061-g004_26702.jpg | What object or scene is depicted here? | Photograph of seedlings showing anthocyanin accumulation.Seedlings were grown on 6% sucrose medium for 15 days. The transgenic line numbers are indicated below the photograph. 2x is diploid, 4x tetraploid. |
PMC2516530_pone-0003061-g004_26706.jpg | What key item or scene is captured in this photo? | Photograph of seedlings showing anthocyanin accumulation.Seedlings were grown on 6% sucrose medium for 15 days. The transgenic line numbers are indicated below the photograph. 2x is diploid, 4x tetraploid. |
PMC2516567_f4-ehp0116-a00338_26708.jpg | What can you see in this picture? | This image sequence taken over an 18-day period in September 2005 shows CO from agricultural fires blooming repeatedly over the Amazon basin, then traveling across the Atlantic Ocean, where it meets CO from fires in sub-Saharan Africa. These images came from the Atmospheric Infrared Sounder Experiment, whose visible, i... |
PMC2516567_f4-ehp0116-a00338_26707.jpg | What can you see in this picture? | This image sequence taken over an 18-day period in September 2005 shows CO from agricultural fires blooming repeatedly over the Amazon basin, then traveling across the Atlantic Ocean, where it meets CO from fires in sub-Saharan Africa. These images came from the Atmospheric Infrared Sounder Experiment, whose visible, i... |
PMC2516567_f4-ehp0116-a00338_26709.jpg | What is the focal point of this photograph? | This image sequence taken over an 18-day period in September 2005 shows CO from agricultural fires blooming repeatedly over the Amazon basin, then traveling across the Atlantic Ocean, where it meets CO from fires in sub-Saharan Africa. These images came from the Atmospheric Infrared Sounder Experiment, whose visible, i... |
PMC2516934_ppat-1000141-g006_26715.jpg | What can you see in this picture? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26713.jpg | What is the principal component of this image? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26716.jpg | What can you see in this picture? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26714.jpg | What is the focal point of this photograph? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26719.jpg | What is the central feature of this picture? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26712.jpg | What is the core subject represented in this visual? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516934_ppat-1000141-g006_26718.jpg | What is shown in this image? | Inhibitors of PI3K, Akt, and Rac1 cause intracellular clustering of ZEBOV particles.(A) HEK293-mCAT-1 cells were grown on chambered coverglass and treated with DMSO (control) or the indicated drugs for 1 h, followed by incubation with fluorescently labeled ZEBOV (red) for 3 h. Cells were fixed, permeabilized, and incub... |
PMC2516937_pone-0003071-g003_26729.jpg | What is the principal component of this image? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26730.jpg | What is the principal component of this image? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26725.jpg | What is being portrayed in this visual content? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26723.jpg | What is the main focus of this visual representation? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26733.jpg | Describe the main subject of this image. | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26732.jpg | What is the core subject represented in this visual? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26724.jpg | What is the main focus of this visual representation? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26722.jpg | What is the focal point of this photograph? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26728.jpg | What is the main focus of this visual representation? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2516937_pone-0003071-g003_26726.jpg | What stands out most in this visual? | Behaviour of grafted cells in the myocardium.A: Immunohistolabelling for GFP with haematoxylin counterstaining detected GFP-positive (brown) cell-clusters disrupting the myocardial structure in the SMB-IM group at day 3. B: In higher magnification of the outlined area in A, the cell-clusters consisted of GFP-positive a... |
PMC2517056_F1_26720.jpg | What key item or scene is captured in this photo? | Chest radiograph showing bilateral interstitial reticular shadowing with loss of lung volume. |
PMC2517056_F2_26721.jpg | What can you see in this picture? | Computed tomography scan of the thorax showing extensive honeycombing in both lungs with widespread ground glass opacification and patchy asymmetrical areas of normal lung tissue. |
PMC2517073_F4_26734.jpg | What can you see in this picture? | Photomicrograph of excised lesion showing a well differentiated lipomatous tumor growth which exhibits at low magnification adipocyte with significant variation in size and shape (A) as well as occasional atypical adipocyte with enlarged hyperchromatic nuclei seen with high magnification (arrow)(B & C) (H&E stained, 5 ... |
PMC2517073_F4_26736.jpg | What stands out most in this visual? | Photomicrograph of excised lesion showing a well differentiated lipomatous tumor growth which exhibits at low magnification adipocyte with significant variation in size and shape (A) as well as occasional atypical adipocyte with enlarged hyperchromatic nuclei seen with high magnification (arrow)(B & C) (H&E stained, 5 ... |
PMC2517073_F4_26735.jpg | What is the principal component of this image? | Photomicrograph of excised lesion showing a well differentiated lipomatous tumor growth which exhibits at low magnification adipocyte with significant variation in size and shape (A) as well as occasional atypical adipocyte with enlarged hyperchromatic nuclei seen with high magnification (arrow)(B & C) (H&E stained, 5 ... |
PMC2518110_pone-0003059-g004_26744.jpg | What key item or scene is captured in this photo? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26751.jpg | What key item or scene is captured in this photo? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26740.jpg | What is the dominant medical problem in this image? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26742.jpg | What is the main focus of this visual representation? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26746.jpg | What object or scene is depicted here? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26752.jpg | What key item or scene is captured in this photo? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26753.jpg | What's the most prominent thing you notice in this picture? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26745.jpg | What key item or scene is captured in this photo? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26748.jpg | What's the most prominent thing you notice in this picture? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26750.jpg | Can you identify the primary element in this image? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26747.jpg | What is the core subject represented in this visual? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26741.jpg | What can you see in this picture? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g004_26749.jpg | What's the most prominent thing you notice in this picture? | Cre-dependent EGFP-F labels distinct neuronal types in the adult forebrain.Confocal microscopy images showing that mosaic EGFP-F expression in a 2 month old TLG 498+ Cre 3487+ mouse occurs in pyramidal cells in (A) neocortex, (C) amygdala and (E) hippocampal CA1; (G) granule cells in the dentate gyrus; (I) marginal cel... |
PMC2518110_pone-0003059-g005_26738.jpg | What is the focal point of this photograph? | Multiple transgenes can be expressed in the same cell.As determined by confocal microscopy, the resulting R26R+ TLG 498+ Cre 3487+ offspring express both EGFP-F (green) and β-galactosidase (red) in a Cre-dependent fashion. β-Galactosidase is predominantly localized perinuclearly and partly in the dendrites whereas EGFP... |
PMC2518110_pone-0003059-g005_26737.jpg | What is the core subject represented in this visual? | Multiple transgenes can be expressed in the same cell.As determined by confocal microscopy, the resulting R26R+ TLG 498+ Cre 3487+ offspring express both EGFP-F (green) and β-galactosidase (red) in a Cre-dependent fashion. β-Galactosidase is predominantly localized perinuclearly and partly in the dendrites whereas EGFP... |
PMC2518115_pone-0003084-g005_26757.jpg | What is the central feature of this picture? | Testing the inducible rep68 expression unit in dHV.68/5′3′.F50 particles purified by CsCl density gradient ultracentrifugation.(A) Western blot analysis of FLPe-induced Rep68 synthesis. HeLa cells were co-transduced with dHV.F50 and hcAd.FLPe.F50 (lane 1) or with dHV.68/5′3′.F50 and hcAd.FLPe.F50 (lane 3) or were trans... |
PMC2518117_pone-0003073-g002_26759.jpg | What key item or scene is captured in this photo? | The volume of HVC of all males was larger compared with all females.Photomicrographs of the Nissl-stained HVC (A, B) and RA (C, D) of a male (A, C) and his female (B, D) mate (parasagittal sections). Arrows indicate the borders of HVC and RA. Scale bar is 100 µm. |
PMC2518117_pone-0003073-g002_26761.jpg | What is the central feature of this picture? | The volume of HVC of all males was larger compared with all females.Photomicrographs of the Nissl-stained HVC (A, B) and RA (C, D) of a male (A, C) and his female (B, D) mate (parasagittal sections). Arrows indicate the borders of HVC and RA. Scale bar is 100 µm. |
PMC2518117_pone-0003073-g002_26760.jpg | Can you identify the primary element in this image? | The volume of HVC of all males was larger compared with all females.Photomicrographs of the Nissl-stained HVC (A, B) and RA (C, D) of a male (A, C) and his female (B, D) mate (parasagittal sections). Arrows indicate the borders of HVC and RA. Scale bar is 100 µm. |
PMC2518119_pone-0003085-g006_26765.jpg | What does this image primarily show? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26764.jpg | Describe the main subject of this image. | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26768.jpg | What is being portrayed in this visual content? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26763.jpg | What is the focal point of this photograph? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26770.jpg | What is the dominant medical problem in this image? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26767.jpg | What key item or scene is captured in this photo? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26771.jpg | What is the central feature of this picture? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518119_pone-0003085-g006_26769.jpg | What stands out most in this visual? | The distribution of MSP1 within late trophozoites and schizonts.Panels A–C show the appearance of the single food vacuole, prepared for EM morphology. Panel A shows a late trophozoite containing a typically dilated food vacuole, containing widely spaced hemozoin and several profiles of internal membranous structures. I... |
PMC2518131_F1_26772.jpg | What is shown in this image? | Computerised abdominal tomography showed splenomegaly and absence of the intrahepatic portion of the portal vein (arrow). |
PMC2518131_F2_26774.jpg | What can you see in this picture? | Computed tomography (CT) of the thorax revealed prominent cardiomegaly and pulmonary vessels. |
PMC2518156_F2_26778.jpg | What is the main focus of this visual representation? | Contrast-enhanced computed tomography scan. Superiorly, this revealed a mixed attenuation, mainly cystic mass with a solid component within its left lateral aspect (arrow). More inferiorly, the lesion was of a more fluid density (arrowhead). These characteristics suggested a teratoma or congenital cystic adenomatoid ma... |
PMC2518156_F2_26777.jpg | What is shown in this image? | Contrast-enhanced computed tomography scan. Superiorly, this revealed a mixed attenuation, mainly cystic mass with a solid component within its left lateral aspect (arrow). More inferiorly, the lesion was of a more fluid density (arrowhead). These characteristics suggested a teratoma or congenital cystic adenomatoid ma... |
PMC2518161_F2_26783.jpg | What does this image primarily show? | Expression of cell cycle regulator p21. Nuclear expression of p21 in hepatocytes of chronic hepatitis C patients, fibrosis stage 2 (F2) and 4 (F4) (Mayer hematoxylin, magnification 400×). |
PMC2518161_F2_26784.jpg | What can you see in this picture? | Expression of cell cycle regulator p21. Nuclear expression of p21 in hepatocytes of chronic hepatitis C patients, fibrosis stage 2 (F2) and 4 (F4) (Mayer hematoxylin, magnification 400×). |
PMC2518161_F3_26781.jpg | What key item or scene is captured in this photo? | Expression of cell cycle regulator p53. Nuclear p53 expression in liver biopsy specimens from chronic hepatitis C patient, grade 1 (G1) and 3 (G3) (Mayer hematoxylin, magnification 400×). |
PMC2518161_F4_26779.jpg | What is the central feature of this picture? | Apoptotic activity in hepatocytes of Hepatitis C patients. Immunostaining in liver biopsies of chronic hepatitis C patient (HCV). a) Caspase-3 expression was observed principally in sinusoidal lining cells (arrow) and rarely in hepatocytes (arrow head), b) Bcl-2 staining observed in inflammatory cells, (magnification 4... |
PMC2518161_F4_26780.jpg | What is the focal point of this photograph? | Apoptotic activity in hepatocytes of Hepatitis C patients. Immunostaining in liver biopsies of chronic hepatitis C patient (HCV). a) Caspase-3 expression was observed principally in sinusoidal lining cells (arrow) and rarely in hepatocytes (arrow head), b) Bcl-2 staining observed in inflammatory cells, (magnification 4... |
PMC2518171_f3_26791.jpg | What is the main focus of this visual representation? | In vivo confocal microscopy images of representative affected family members. The right eye (virgin cornea) of the proband (frame size 400 µm x 400 µm) at the level of (A) basal epithelial layer illustrating focal deposition of homogeneous, reflective materials with rounded edges, and hyporeflective borders and (B) po... |
PMC2518171_f3_26792.jpg | What is the dominant medical problem in this image? | In vivo confocal microscopy images of representative affected family members. The right eye (virgin cornea) of the proband (frame size 400 µm x 400 µm) at the level of (A) basal epithelial layer illustrating focal deposition of homogeneous, reflective materials with rounded edges, and hyporeflective borders and (B) po... |
PMC2518171_f3_26789.jpg | What is the central feature of this picture? | In vivo confocal microscopy images of representative affected family members. The right eye (virgin cornea) of the proband (frame size 400 µm x 400 µm) at the level of (A) basal epithelial layer illustrating focal deposition of homogeneous, reflective materials with rounded edges, and hyporeflective borders and (B) po... |
PMC2518171_f3_26790.jpg | Describe the main subject of this image. | In vivo confocal microscopy images of representative affected family members. The right eye (virgin cornea) of the proband (frame size 400 µm x 400 µm) at the level of (A) basal epithelial layer illustrating focal deposition of homogeneous, reflective materials with rounded edges, and hyporeflective borders and (B) po... |
PMC2518171_f4_26785.jpg | What is the main focus of this visual representation? | Transmission electron microscopy images of the corneal allograft from subject II:1. A: Low magnification photomicrograph showing basal epithelial cells (Ep) overlying a band of deposit (De), at higher magnification in B. The insert in B is shown in higher magnification in C, demonstrating the degenerating basal epithel... |
PMC2518171_f4_26787.jpg | What stands out most in this visual? | Transmission electron microscopy images of the corneal allograft from subject II:1. A: Low magnification photomicrograph showing basal epithelial cells (Ep) overlying a band of deposit (De), at higher magnification in B. The insert in B is shown in higher magnification in C, demonstrating the degenerating basal epithel... |
PMC2518171_f4_26786.jpg | Describe the main subject of this image. | Transmission electron microscopy images of the corneal allograft from subject II:1. A: Low magnification photomicrograph showing basal epithelial cells (Ep) overlying a band of deposit (De), at higher magnification in B. The insert in B is shown in higher magnification in C, demonstrating the degenerating basal epithel... |
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