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PMC1831740_pmed-0040108-g005_10125.jpg | What does this image primarily show? |
OLIG1 Immunohistochemistry on a Lung Tissue Array
OLIG1 immunohistochemistry on (A and E) tumor-free lung, (B) an OLIG1 negative adenocarcinoma, and (F) an OLIG1 negative SCC; (C) a low OLIG1 expressing adenocarcinoma and (G) a low OLIG1 expressing SCC are shown; (D) a high OLIG1 expressing adenocarcinoma and (H) a high OLIG1 expressing SCC are shown. All images were acquired at 400× magnification. |
PMC1831761_F1_10142.jpg | What is shown in this image? | Full-field 2-D projection images created using phase-contrast synchrotron x-rays. Images were chosen to highlight the highest quality imagery currently obtainable (a, b) and corresponding stills from live video (c-l). (a) Carabid beetle (Pterostichus stygicus) in dorsoventral view with legs removed and sacrificed prior to imaging. Image is a high-resolution composite of multiple images. The air-filled tubes of the tracheal system can be prominently seen. The dark spots on the left side, mid-body are soil particles on the outer surface of the elytra. (b) Close-in view of one section of the prothorax, showing the branching pattern of tracheae. (c, d) One half-cycle of rhythmic tracheal collapse in a live carabid beetle (Platynus decentis) in dorsoventral view. Images are frame grabs from a video recording (See Additional file 1); time interval is 0.5 s. Total time of collapse and reinflation of the tubes is 1.0 s. (e-l) Visualization of internal food movement using labeled markers. (e) Schematic of the head and thorax of a butterfly (Pieris rapae) in lateral view. The foregut is shown in red; the square highlights the region of video stills in (f-h), and black arrow indicates the direction of food movement. (f-h) Video stills of passage of a food bolus posteriorly through the esophagus, moving through the frame from upper right to lower left (see Additional file 2). Red arrows indicate the leading (f) and trailing (h) edges of the bolus. Interval between frames is 0.5 s. Food is sugar water/iodine mixture. X-ray energy (33.2 keV) was tuned to just above the K-edge absorption band for iodine. (i) Schematic of a carabid beetle (Pterostichus stygicus) in dorsoventral view (legs removed). Circular structures in mid-body represent coxae; the gut is represented in gray and red. Square highlights video in (j-l), visualization of cadmium-laced food in the foregut (see additional file 3). Video stills (j-l) show movement of gut including anterior-posterior translation and squeezing of the crop (cr) and translation and rotation of the proventriculus (pr). The proventriculus is a valve that leads to the midgut [41]; here, it is closed. Note that only parts of the gut with contrast agent can be seen. Interval between frames: j-k, 2 s; k-l, 6 s. X-ray energy, 25 keV. Scale bars: a,b, 1 mm; c,d, 200 μm; f-h, 200 μm; j-l, 1 mm. |
PMC1831761_F1_10145.jpg | What is the principal component of this image? | Full-field 2-D projection images created using phase-contrast synchrotron x-rays. Images were chosen to highlight the highest quality imagery currently obtainable (a, b) and corresponding stills from live video (c-l). (a) Carabid beetle (Pterostichus stygicus) in dorsoventral view with legs removed and sacrificed prior to imaging. Image is a high-resolution composite of multiple images. The air-filled tubes of the tracheal system can be prominently seen. The dark spots on the left side, mid-body are soil particles on the outer surface of the elytra. (b) Close-in view of one section of the prothorax, showing the branching pattern of tracheae. (c, d) One half-cycle of rhythmic tracheal collapse in a live carabid beetle (Platynus decentis) in dorsoventral view. Images are frame grabs from a video recording (See Additional file 1); time interval is 0.5 s. Total time of collapse and reinflation of the tubes is 1.0 s. (e-l) Visualization of internal food movement using labeled markers. (e) Schematic of the head and thorax of a butterfly (Pieris rapae) in lateral view. The foregut is shown in red; the square highlights the region of video stills in (f-h), and black arrow indicates the direction of food movement. (f-h) Video stills of passage of a food bolus posteriorly through the esophagus, moving through the frame from upper right to lower left (see Additional file 2). Red arrows indicate the leading (f) and trailing (h) edges of the bolus. Interval between frames is 0.5 s. Food is sugar water/iodine mixture. X-ray energy (33.2 keV) was tuned to just above the K-edge absorption band for iodine. (i) Schematic of a carabid beetle (Pterostichus stygicus) in dorsoventral view (legs removed). Circular structures in mid-body represent coxae; the gut is represented in gray and red. Square highlights video in (j-l), visualization of cadmium-laced food in the foregut (see additional file 3). Video stills (j-l) show movement of gut including anterior-posterior translation and squeezing of the crop (cr) and translation and rotation of the proventriculus (pr). The proventriculus is a valve that leads to the midgut [41]; here, it is closed. Note that only parts of the gut with contrast agent can be seen. Interval between frames: j-k, 2 s; k-l, 6 s. X-ray energy, 25 keV. Scale bars: a,b, 1 mm; c,d, 200 μm; f-h, 200 μm; j-l, 1 mm. |
PMC1831761_F1_10141.jpg | What is the central feature of this picture? | Full-field 2-D projection images created using phase-contrast synchrotron x-rays. Images were chosen to highlight the highest quality imagery currently obtainable (a, b) and corresponding stills from live video (c-l). (a) Carabid beetle (Pterostichus stygicus) in dorsoventral view with legs removed and sacrificed prior to imaging. Image is a high-resolution composite of multiple images. The air-filled tubes of the tracheal system can be prominently seen. The dark spots on the left side, mid-body are soil particles on the outer surface of the elytra. (b) Close-in view of one section of the prothorax, showing the branching pattern of tracheae. (c, d) One half-cycle of rhythmic tracheal collapse in a live carabid beetle (Platynus decentis) in dorsoventral view. Images are frame grabs from a video recording (See Additional file 1); time interval is 0.5 s. Total time of collapse and reinflation of the tubes is 1.0 s. (e-l) Visualization of internal food movement using labeled markers. (e) Schematic of the head and thorax of a butterfly (Pieris rapae) in lateral view. The foregut is shown in red; the square highlights the region of video stills in (f-h), and black arrow indicates the direction of food movement. (f-h) Video stills of passage of a food bolus posteriorly through the esophagus, moving through the frame from upper right to lower left (see Additional file 2). Red arrows indicate the leading (f) and trailing (h) edges of the bolus. Interval between frames is 0.5 s. Food is sugar water/iodine mixture. X-ray energy (33.2 keV) was tuned to just above the K-edge absorption band for iodine. (i) Schematic of a carabid beetle (Pterostichus stygicus) in dorsoventral view (legs removed). Circular structures in mid-body represent coxae; the gut is represented in gray and red. Square highlights video in (j-l), visualization of cadmium-laced food in the foregut (see additional file 3). Video stills (j-l) show movement of gut including anterior-posterior translation and squeezing of the crop (cr) and translation and rotation of the proventriculus (pr). The proventriculus is a valve that leads to the midgut [41]; here, it is closed. Note that only parts of the gut with contrast agent can be seen. Interval between frames: j-k, 2 s; k-l, 6 s. X-ray energy, 25 keV. Scale bars: a,b, 1 mm; c,d, 200 μm; f-h, 200 μm; j-l, 1 mm. |
PMC1831761_F1_10143.jpg | What does this image primarily show? | Full-field 2-D projection images created using phase-contrast synchrotron x-rays. Images were chosen to highlight the highest quality imagery currently obtainable (a, b) and corresponding stills from live video (c-l). (a) Carabid beetle (Pterostichus stygicus) in dorsoventral view with legs removed and sacrificed prior to imaging. Image is a high-resolution composite of multiple images. The air-filled tubes of the tracheal system can be prominently seen. The dark spots on the left side, mid-body are soil particles on the outer surface of the elytra. (b) Close-in view of one section of the prothorax, showing the branching pattern of tracheae. (c, d) One half-cycle of rhythmic tracheal collapse in a live carabid beetle (Platynus decentis) in dorsoventral view. Images are frame grabs from a video recording (See Additional file 1); time interval is 0.5 s. Total time of collapse and reinflation of the tubes is 1.0 s. (e-l) Visualization of internal food movement using labeled markers. (e) Schematic of the head and thorax of a butterfly (Pieris rapae) in lateral view. The foregut is shown in red; the square highlights the region of video stills in (f-h), and black arrow indicates the direction of food movement. (f-h) Video stills of passage of a food bolus posteriorly through the esophagus, moving through the frame from upper right to lower left (see Additional file 2). Red arrows indicate the leading (f) and trailing (h) edges of the bolus. Interval between frames is 0.5 s. Food is sugar water/iodine mixture. X-ray energy (33.2 keV) was tuned to just above the K-edge absorption band for iodine. (i) Schematic of a carabid beetle (Pterostichus stygicus) in dorsoventral view (legs removed). Circular structures in mid-body represent coxae; the gut is represented in gray and red. Square highlights video in (j-l), visualization of cadmium-laced food in the foregut (see additional file 3). Video stills (j-l) show movement of gut including anterior-posterior translation and squeezing of the crop (cr) and translation and rotation of the proventriculus (pr). The proventriculus is a valve that leads to the midgut [41]; here, it is closed. Note that only parts of the gut with contrast agent can be seen. Interval between frames: j-k, 2 s; k-l, 6 s. X-ray energy, 25 keV. Scale bars: a,b, 1 mm; c,d, 200 μm; f-h, 200 μm; j-l, 1 mm. |
PMC1831762_F5_10136.jpg | What's the most prominent thing you notice in this picture? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10135.jpg | What does this image primarily show? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10134.jpg | What's the most prominent thing you notice in this picture? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10138.jpg | What is the focal point of this photograph? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10137.jpg | What key item or scene is captured in this photo? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10133.jpg | Can you identify the primary element in this image? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831762_F5_10139.jpg | What is the core subject represented in this visual? | Non-human primate orthotopic (bone) bioassay – Histology. (A-D): samples of alveolar bone implanted with DFDBA. (E-H): Samples of alveolar bone implanted with CS-Platelet. All grafted sites, whether implanted with CS-Platelet or with DFDBA, showed regeneration of trabecular bone. In the sites grafted with DFDBA some residual biomaterial was still visible (B, black arrows). Hematoxylin and Eosin staining. (A and E, 40× original magnification). (B-D and F-H, 100× original magnification). |
PMC1831769_F1_10148.jpg | What can you see in this picture? | Humanoid abdominal/pelvic phantom. |
PMC1831769_F5_10151.jpg | What is the focal point of this photograph? | Pelvic CT image of Humanoid phantom. Pelvic CT image with gonad shield in place and directly situated in the beam. Note the severe streaking artifacts and general image degradation. |
PMC1831769_F5_10149.jpg | What's the most prominent thing you notice in this picture? | Pelvic CT image of Humanoid phantom. Pelvic CT image with gonad shield in place and directly situated in the beam. Note the severe streaking artifacts and general image degradation. |
PMC1831770_F1_10152.jpg | What is being portrayed in this visual content? | tBHP induced and increase intracellular oxidative stress in H9c2 cells. (Top panel) H9c2 cells were exposed to 0 (panel A-B) or 50 μM tBHP (panel C-D) for 1 hour. Increase in intracellular oxidative stress was detected by oxidation of dichlorofluorescein. Fluorescence observed in panel B and D is proportional to the degree of oxidation. The corresponding DIC images can be observed in panels A and C. Images are representative from 3 different cell preparations. A-D are the same magnification; scale bar in A = 20 μm. (Bottom panel) Quantification of cell DCF fluorescence intensity. Four different fields were analyzed in each experiment. Data represents the mean ± SEM of 3 different cell preparations. *p < 0.05 vs control. |
PMC1831770_F1_10153.jpg | What's the most prominent thing you notice in this picture? | tBHP induced and increase intracellular oxidative stress in H9c2 cells. (Top panel) H9c2 cells were exposed to 0 (panel A-B) or 50 μM tBHP (panel C-D) for 1 hour. Increase in intracellular oxidative stress was detected by oxidation of dichlorofluorescein. Fluorescence observed in panel B and D is proportional to the degree of oxidation. The corresponding DIC images can be observed in panels A and C. Images are representative from 3 different cell preparations. A-D are the same magnification; scale bar in A = 20 μm. (Bottom panel) Quantification of cell DCF fluorescence intensity. Four different fields were analyzed in each experiment. Data represents the mean ± SEM of 3 different cell preparations. *p < 0.05 vs control. |
PMC1831770_F3_10160.jpg | What key item or scene is captured in this photo? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10159.jpg | What is the core subject represented in this visual? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10164.jpg | What's the most prominent thing you notice in this picture? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10157.jpg | What's the most prominent thing you notice in this picture? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10162.jpg | What stands out most in this visual? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10158.jpg | What is the main focus of this visual representation? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831770_F3_10161.jpg | What stands out most in this visual? | Alterations in cellular and mitochondrial morphology induced by tBHP. (A) DIC images from untreated cells, showing normal membrane morphology. (B) Laser scanning confocal microscopy image from untreated cells showing triple labeling with Hoechst 33342 (blue), calcein (green) and TMRM (red). (C, D) Laser scanning confocal microscopy showing the fluorescence of the three dyes followed with the time, (C) 45 min, and (D) 90 minutes, after treatment with 80 μM tBHP. (E) Magnification of the cell indicated by an arrow in panel C and (F) magnification of the cell indicated by an arrow in panel D. (G) DIC images from H9c2 cells treated with 25 μM tBHP for three hours. (H) Laser scanning confocal microscopy (LSCM) image from cells treated with 25 μM tBHP during three hours. Images are representative from 3 different cell preparations. Panels B-D and G, H are the same magnification. Scale bar corresponds to 20 μm. |
PMC1831774_F1_10165.jpg | What is shown in this image? | Pre-operative chest X-ray demonstrating a round shadow of approx. 5 cm in diameter in the left pulmonary apex. |
PMC1831774_F3_10166.jpg | What is shown in this image? | Coronal section of T1 weighted MRI demonstrating the left pulmonary apex tumor with extension into T1-2 intervertebral foramen. |
PMC1831774_F4_10167.jpg | What does this image primarily show? | Transverse section of T1 weighted MRI demonstrating protrusion of the tumor from the left T1-2 intervertebral foramen to the spinal cord. |
PMC1831774_F7_10168.jpg | What's the most prominent thing you notice in this picture? | Coronal section of T1 weighted MRI demonstrating complete removal of the left-sided T1-neuroma from the T1-2 intervertebral foramen and from the pulmonary apex. |
PMC1831780_F1_10169.jpg | What stands out most in this visual? | (A) Gastrografin swallow and (B) computed tomography showing the anastomotic leakage (arrows). (C) Endoscopic view of the same region. |
PMC1831780_F1_10170.jpg | What is being portrayed in this visual content? | (A) Gastrografin swallow and (B) computed tomography showing the anastomotic leakage (arrows). (C) Endoscopic view of the same region. |
PMC1831780_F1_10171.jpg | What can you see in this picture? | (A) Gastrografin swallow and (B) computed tomography showing the anastomotic leakage (arrows). (C) Endoscopic view of the same region. |
PMC1832177_F2_10175.jpg | What is the dominant medical problem in this image? | Female embryo (left) and male embryo (right), both infected with S. poulsonii (16–18 h AEL). The top pictures, A and B, shows fluorescence with anti-SXL antibody in female and male respectively, and the bottom pictures, C and D, show the embryos structure under DAPI in female and male respectively. The female has developed normally and reached stage 16, the male has arrested before segmentation, and shows a characteristic amnioseral bulge. |
PMC1832177_F2_10174.jpg | What is the principal component of this image? | Female embryo (left) and male embryo (right), both infected with S. poulsonii (16–18 h AEL). The top pictures, A and B, shows fluorescence with anti-SXL antibody in female and male respectively, and the bottom pictures, C and D, show the embryos structure under DAPI in female and male respectively. The female has developed normally and reached stage 16, the male has arrested before segmentation, and shows a characteristic amnioseral bulge. |
PMC1832177_F2_10176.jpg | What is the principal component of this image? | Female embryo (left) and male embryo (right), both infected with S. poulsonii (16–18 h AEL). The top pictures, A and B, shows fluorescence with anti-SXL antibody in female and male respectively, and the bottom pictures, C and D, show the embryos structure under DAPI in female and male respectively. The female has developed normally and reached stage 16, the male has arrested before segmentation, and shows a characteristic amnioseral bulge. |
PMC1832177_F3_10173.jpg | What is shown in this image? | TUNEL staining of Spiroplasma infected male embryo (A) and female embryo (B), both at stage 10, 5–7 h AEL. Red fluorescence indicates apoptotic nuclei; whilst the female embryo shows the characteristic pattern of apoptotic nuclei restricted to the cephalic furrow, apoptotic nuclei are observed throughout the male. |
PMC1832187_F2_10180.jpg | Describe the main subject of this image. | pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled. |
PMC1832187_F2_10182.jpg | What key item or scene is captured in this photo? | pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled. |
PMC1832187_F2_10177.jpg | What is the core subject represented in this visual? | pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled. |
PMC1832187_F2_10178.jpg | What can you see in this picture? | pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled. |
PMC1832187_F2_10179.jpg | What is the dominant medical problem in this image? | pattern of S100B gene expression in the cerebellum and inferior colliculus before midline fusion of the cerebellar plates (E13.5). A: lower power confocal image of the Cb primordium, illustrating the strong EGFP signal present near the MHB (red box) in a parasagittal section. B: zooming on the boxed area in A reveals the high level of S100B/EGFP colocalisation at the single cell level. C: near the MHB, and on coronal sections, EGFP tags a stretch of neuroepithelial cells approx. 300 μM in width, emitting thin processes towards the pial surface (arrowheads). The red dotted lines represent the approximate planes of sections D and F. The glial scaffold (boxed area) is entirely (D, E) or only partially visible (F), depending on how close to the midline is the plane of section. E: higher magnification of the boxed area in (D) illustrating the pattern of EGFP expression near the midline: both the S-shaped radial glial scaffold of the Cb, and the abutting IC neuroepithelium, are strongly labeled. |
PMC1832205_F1_10184.jpg | What can you see in this picture? | Top, endometrial curetting showed aggregates of plump mononuclear cells with numerous large multinucleated osteoclast-type giant cells. Benign endometrial glands are seen at right center and right upper corner. Bottom, Fine needle aspirate of the lung showed sheets of mononuclear plump cells and numerous scattered osteoclast-type giant cells. See the text for complete pathologic description. |
PMC1832205_F1_10185.jpg | What is being portrayed in this visual content? | Top, endometrial curetting showed aggregates of plump mononuclear cells with numerous large multinucleated osteoclast-type giant cells. Benign endometrial glands are seen at right center and right upper corner. Bottom, Fine needle aspirate of the lung showed sheets of mononuclear plump cells and numerous scattered osteoclast-type giant cells. See the text for complete pathologic description. |
PMC1832205_F2_10186.jpg | What is the main focus of this visual representation? | CT scan at start of chemotherapy. |
PMC1832205_F3_10189.jpg | What stands out most in this visual? | CT scan at start of chemotherapy cycle #2. |
PMC1832205_F3_10188.jpg | What is the central feature of this picture? | CT scan at start of chemotherapy cycle #2. |
PMC1832205_F4_10191.jpg | Describe the main subject of this image. | CT scan at start of chemotherapy cycle #8. |
PMC1832205_F4_10190.jpg | What is the focal point of this photograph? | CT scan at start of chemotherapy cycle #8. |
PMC1838406_F2_10194.jpg | What is the main focus of this visual representation? | Magnetic resonance T1-weighted contrast-enhanced imaging; sagittal view. |
PMC1838406_F3_10193.jpg | What object or scene is depicted here? | Magnetic resonance T1-weighted contrast-enhanced imaging; coronal view. |
PMC1838406_F3_10192.jpg | What object or scene is depicted here? | Magnetic resonance T1-weighted contrast-enhanced imaging; coronal view. |
PMC1838416_F2_10195.jpg | What is the main focus of this visual representation? | Preliminary imaging procedure using the gold needle inserted into an onion. Note the image attenuation area around the needle. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle. |
PMC1838416_F3_10197.jpg | What does this image primarily show? | Preliminary imaging procedure using the gold needle inserted into a banana. Note the image attenuation area around the needle similar to that shown in figure 2. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle. |
PMC1838416_F3_10198.jpg | What's the most prominent thing you notice in this picture? | Preliminary imaging procedure using the gold needle inserted into a banana. Note the image attenuation area around the needle similar to that shown in figure 2. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle. |
PMC1838416_F3_10196.jpg | What is the focal point of this photograph? | Preliminary imaging procedure using the gold needle inserted into a banana. Note the image attenuation area around the needle similar to that shown in figure 2. In these experiments the length of the inserted portion corresponded to the length of the image attenuation effect. The width of the defect was much larger than the width of the gold needle. |
PMC1838416_F4_10199.jpg | Can you identify the primary element in this image? | In-vivo localisation of the gold acupuncture needle inserted into the Dai mai point as seen in a saggital slice reconstruction. The white arrow simulates the direction of needle insertion. Image reconstruction was done with the J-Vision software of the TIANI workstation. MRI acquisition data: TR = 721, TE = 19, flip = 150, TH = 3, TF = 3, FOV = 370, MA = 320. |
PMC1838416_F5_10205.jpg | What stands out most in this visual? | In-vivo localisation of the gold acupuncture needle inserted into the Dai mai point. The site of needle insertion is indicated by the white arrow. Image processing and reconstruction was done using the 3D volume rendering procedure of the multimodality module on the Hermes workstation. The color coding of the image allows the easy recognition of muscular structures of the abdomen. In this reconstruction the void effect of the gold needle is seen as a black area which reaches the muscular structures of the internal oblique muscle. Original MRI acquisition data: TR = 721, TE = 19, flip = 150, TH = 3, TF = 3, FOV = 370, MA = 320. |
PMC1838416_F7_10200.jpg | What can you see in this picture? | Flow chart showing a summary of the study including the preliminary evaluations, the non-human images, and the human in-vivo imaging. |
PMC1838416_F7_10202.jpg | Can you identify the primary element in this image? | Flow chart showing a summary of the study including the preliminary evaluations, the non-human images, and the human in-vivo imaging. |
PMC1838913_F2_10206.jpg | What is being portrayed in this visual content? | Source localizations of responses to index finger stimulation alone. Identified dipole sources of responses in the right hemisphere shown in Figure 1 are superimposed on this subject's MRI. The left horizontal (a) and sagittal (b) slices show the locations of early contralateral response (green dot in right anterior parietal field) to LD2 stimulation and early ipsilateral response (red dot) to RD2 stimulation. The coronal (c) and sagittal (d) slices in the right column show the locations of the late contralateral response (yellow dot in right S2) to LD2 stimulation and late ipsilateral response (cyan dot) to RD2 stimulation. The tails of those dots indicate dipoles' strength and direction. |
PMC1838913_F2_10207.jpg | What object or scene is depicted here? | Source localizations of responses to index finger stimulation alone. Identified dipole sources of responses in the right hemisphere shown in Figure 1 are superimposed on this subject's MRI. The left horizontal (a) and sagittal (b) slices show the locations of early contralateral response (green dot in right anterior parietal field) to LD2 stimulation and early ipsilateral response (red dot) to RD2 stimulation. The coronal (c) and sagittal (d) slices in the right column show the locations of the late contralateral response (yellow dot in right S2) to LD2 stimulation and late ipsilateral response (cyan dot) to RD2 stimulation. The tails of those dots indicate dipoles' strength and direction. |
PMC1838913_F2_10208.jpg | What is shown in this image? | Source localizations of responses to index finger stimulation alone. Identified dipole sources of responses in the right hemisphere shown in Figure 1 are superimposed on this subject's MRI. The left horizontal (a) and sagittal (b) slices show the locations of early contralateral response (green dot in right anterior parietal field) to LD2 stimulation and early ipsilateral response (red dot) to RD2 stimulation. The coronal (c) and sagittal (d) slices in the right column show the locations of the late contralateral response (yellow dot in right S2) to LD2 stimulation and late ipsilateral response (cyan dot) to RD2 stimulation. The tails of those dots indicate dipoles' strength and direction. |
PMC1839090_F1_10209.jpg | What is the principal component of this image? | A trans-scapular roentgenogram shows the pedunculated shape of an osteochondorma at the inferior aspect of the anterior scapula. |
PMC1839090_F3_10210.jpg | What does this image primarily show? | Endoscopic image shows that the tumor was removed by use of a grasper. |
PMC1839091_F1_10213.jpg | Can you identify the primary element in this image? | Computed tomography, A – multiple focal changes in liver are visible, B – multiple metastases to lungs are visible. |
PMC1839091_F1_10214.jpg | What is the core subject represented in this visual? | Computed tomography, A – multiple focal changes in liver are visible, B – multiple metastases to lungs are visible. |
PMC1839091_F2_10211.jpg | Can you identify the primary element in this image? | Computed tomography after chemotherapy A – regression of focal changes in liver is visible B – regression of metastases in lungs is visible. |
PMC1839091_F2_10212.jpg | What can you see in this picture? | Computed tomography after chemotherapy A – regression of focal changes in liver is visible B – regression of metastases in lungs is visible. |
PMC1839762_F1_10215.jpg | What is the central feature of this picture? | Axial FLAIR sequence magnetic resonance image of brain at admission. There are hyperintense multifocal lesions in the deep grey nuclei, subcortical white matter and cortex. |
PMC1839762_F2_10216.jpg | What is the principal component of this image? | Sagittal T2-weighted magnetic resonance image of spine at admission. There is longitudinal hyperintense signal involving the central cord from C1 downwards. |
PMC1839766_F1_10221.jpg | What stands out most in this visual? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10224.jpg | What is shown in this image? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10217.jpg | What does this image primarily show? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10218.jpg | What does this image primarily show? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10223.jpg | What is being portrayed in this visual content? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10222.jpg | What does this image primarily show? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1839766_F1_10220.jpg | What key item or scene is captured in this photo? | T2* weighted spiral imaging of the right common carotid artery in-vivo, pre (A) and 36 hours post USPIO infusion (B) showing signal loss in areas of USPIO uptake (yellow arrows). (The 2D T2* weighted spiral acquisition used a spectral-spatial excitation pulse, with a TE of 5.6 ms. The multi-shot spiral sequence involved the acquisition of 22 spiral interleafs each of 4096 data points resulting in an effective in-plane pixel size of 0.42 × 0.42 mm, two signal averages were performed and a quadruple inversion preparation was utilised to null the signal from blood pre – and post USPIO. Slices were acquired sequentially with a 3 mm thickness and no inter-slice gap.). Pre (C) and 36 hours post USPIO infusion (F) T2* weighted spiral imaging in-vivo revealing signal drop in the wall of the aneurysm post-USPIO (yellow arrows) likely corresponding to regions with a high inflammatory burden. Corresponding ex-vivo imaging in a dedicated micro-coil with T2 map (D) showing regions with very short T2 species (yellow arrow) corresponding with area of USPIO uptake. Ex-vivo inversion recovery on-resonance water suppression (IRON) imaging [9] (E) with off-resonant spins showing positive contrast due to dephasing of spins adjacent to USPIO uptake. H&E section (x40) co-registered with ex-vivo imaging (using distance from the bifurcation). Area of intraplaque haemorrhage within a small necrotic lipid core can be seen (red arrow), adjacent to the USPIO uptake seen in the ex-vivo imaging. Structural MR Imaging in the same patient reveals anatomy of the co-existing abdominal aortic aneurysm (H&J). |
PMC1845144_F3_10227.jpg | What is the main focus of this visual representation? | Radiographic comparison. A. Lateral extra-oral radiograph for preoperative cephalometric investigation of a retrognathic patient. Skeletal image of the retropositioned mandible can be seen in type II occlusal relationship. Soft structures show characteristic deep mentolabial sulcus and small facial height. B. Postoperative lateral extra-oral radiograph. Alveolar osteotomy can be seen from 32 to 42, associated to advancement and clockwise rotation of the mandible making up a maxilla-combined surgery. The surgery begins at the mandible. Rigid fixation miniplates measuring 2 mm are used in an extension of six holes for an advancement of 13 mm. On the maxilla, 1.5 mm rigid fixation may be observed. Soft tissue profile in accordance with skeletal results. In the naso-oro-hypopharyngeal regions, pre- and postoperative images show transversal increase of the area. This result is supported by respiratory improvement, as clinically reported by the patient. |
PMC1845149_F1_10231.jpg | What key item or scene is captured in this photo? | a) Original TRUS Image1, b) Manually Segmented, c)Second Eigenvector. |
PMC1845149_F1_10230.jpg | What stands out most in this visual? | a) Original TRUS Image1, b) Manually Segmented, c)Second Eigenvector. |
PMC1845149_F1_10229.jpg | What is being portrayed in this visual content? | a) Original TRUS Image1, b) Manually Segmented, c)Second Eigenvector. |
PMC1845149_F3_10237.jpg | What's the most prominent thing you notice in this picture? | a) the obtained segmentation using the implemented algorithm, b) the contour map overlapped on the original TRUS image. |
PMC1845149_F5_10234.jpg | What is the principal component of this image? | Original TRUS Image2, Manually Segmented, Second Eigenvector. |
PMC1845149_F5_10233.jpg | What is the core subject represented in this visual? | Original TRUS Image2, Manually Segmented, Second Eigenvector. |
PMC1845149_F5_10235.jpg | What is the central feature of this picture? | Original TRUS Image2, Manually Segmented, Second Eigenvector. |
PMC1845149_F8_10239.jpg | What is shown in this image? | Original TRUS Image3, Manually Segmented, Second Eigenvector. |
PMC1845149_F8_10238.jpg | What is the principal component of this image? | Original TRUS Image3, Manually Segmented, Second Eigenvector. |
PMC1847429_F1_10241.jpg | What is the main focus of this visual representation? | a Posterior anterior chest x-ray of 57-yr-old male with T3N2M1 non-small cell lung cancer demonstrates a left hilar mass with loss of volume and/or post obstructive pneumonia in the left lower lobe. b Axial computed tomography chest angiogram demonstrates total occlusion of the left mainstem bronchus by a tumor invading from the left hilum. |
PMC1847429_F2_10243.jpg | What object or scene is depicted here? | a Videobronchoscopy image demonstrates distal left mainstem bronchus occlusion. b Videobronchoscopy image demonstrates debridement of malignant distal mainstem occlusion with the rotating tip tracheal microdebrider after argon plasma coagulation. c Videobronchoscopy image demonstrates a nitinol self-expandable metal stent in the previously occluded left mainstem bronchus. |
PMC1847429_F2_10244.jpg | What key item or scene is captured in this photo? | a Videobronchoscopy image demonstrates distal left mainstem bronchus occlusion. b Videobronchoscopy image demonstrates debridement of malignant distal mainstem occlusion with the rotating tip tracheal microdebrider after argon plasma coagulation. c Videobronchoscopy image demonstrates a nitinol self-expandable metal stent in the previously occluded left mainstem bronchus. |
PMC1847445_F2_10254.jpg | What is the central feature of this picture? | Colonoscopic picture of patient 1 at first presentation showing stenosis of the sigmoid which could not be passed by the colonoscope (A). Endoscopic snare debulking of the distal part of the tumor allowed to push the wire beyond the stenosis (B). After passing the tumor APC ablation of the proximal part of the tumor could be performed opening a channel (C). View of the stenosis after complete debulking. Note the channel with stool covering the luminal surface (D). |
PMC1847445_F2_10253.jpg | What key item or scene is captured in this photo? | Colonoscopic picture of patient 1 at first presentation showing stenosis of the sigmoid which could not be passed by the colonoscope (A). Endoscopic snare debulking of the distal part of the tumor allowed to push the wire beyond the stenosis (B). After passing the tumor APC ablation of the proximal part of the tumor could be performed opening a channel (C). View of the stenosis after complete debulking. Note the channel with stool covering the luminal surface (D). |
PMC1847445_F2_10252.jpg | What does this image primarily show? | Colonoscopic picture of patient 1 at first presentation showing stenosis of the sigmoid which could not be passed by the colonoscope (A). Endoscopic snare debulking of the distal part of the tumor allowed to push the wire beyond the stenosis (B). After passing the tumor APC ablation of the proximal part of the tumor could be performed opening a channel (C). View of the stenosis after complete debulking. Note the channel with stool covering the luminal surface (D). |
PMC1847445_F3_10248.jpg | What can you see in this picture? | Abdominal X-ray of patient 2 at the time of first presentation showing complete colon obstruction and dilatation (A). Colonoscopic view of the sigmoid tumor with complete obstruction (B). Colonoscopic view during APC ablation of the tumor (C); X-ray enema two days after APC ablation showing the channel through the stenosis (D). |
PMC1847445_F3_10247.jpg | What is shown in this image? | Abdominal X-ray of patient 2 at the time of first presentation showing complete colon obstruction and dilatation (A). Colonoscopic view of the sigmoid tumor with complete obstruction (B). Colonoscopic view during APC ablation of the tumor (C); X-ray enema two days after APC ablation showing the channel through the stenosis (D). |
PMC1847510_F1_10256.jpg | Describe the main subject of this image. | Example of bedside measurement of spectral Doppler velocities (cm/s) in the apical 4-chamber view in a 82 years-old woman hospitalized for new-onset congestive heart failure with preserved left ventricular systolic function related to longstanding hypertension. At presentation, the score of Boston criteria was 10 and B-type natriuretic peptide concentration 460 pg/ml. Bedside Doppler echocardiography performed before unloading therapy showed a left ventricular ejection fraction of 67% (upper part); peak E mitral velocity between the tips of mitral leaflets was 101 cm/s, spectral tissue Doppler peak early diastolic E' velocities at the septal (middle part) and lateral corner of mitral annulus (lower part) were 6 and 9 cm/s, respectively. The patient experienced a complete relief of symptoms and signs of pulmonary congestion under unloading therapy. Invasive left ventricular end-diastolic pressure recorded after clinical stabilization was 14 mm Hg. |
PMC1847512_F2_10259.jpg | What's the most prominent thing you notice in this picture? | Comparison of SG and DAPI using fluorescence microscopy. Chloroplasts isolated from seedlings at 20 days after imbibition stained with DAPI (B) or SG (D). (A, C) Brightfield images of the chloroplasts shown in (B) and (D). The contrast has been enhanced (inset in (B)) to accentuate fluorescence from the chloroplasts in the lower left quadrant. Scale bar is 10 μm. The exposure time for both (B) and (D) was 0.5 s. DAPI-stained chloroplasts were fixed in glutaraldehyde and SG-stained chloroplasts were not fixed. |
PMC1847512_F2_10258.jpg | Describe the main subject of this image. | Comparison of SG and DAPI using fluorescence microscopy. Chloroplasts isolated from seedlings at 20 days after imbibition stained with DAPI (B) or SG (D). (A, C) Brightfield images of the chloroplasts shown in (B) and (D). The contrast has been enhanced (inset in (B)) to accentuate fluorescence from the chloroplasts in the lower left quadrant. Scale bar is 10 μm. The exposure time for both (B) and (D) was 0.5 s. DAPI-stained chloroplasts were fixed in glutaraldehyde and SG-stained chloroplasts were not fixed. |
PMC1847679_F5_10262.jpg | What's the most prominent thing you notice in this picture? | Sampling procedure. Dental excavator3 inserted into a carious lesion. |
PMC1847680_F2_10264.jpg | What is the central feature of this picture? | Case 1: Computed tomography showing the growth with pressure on the trachea. |
PMC1847680_F2_10263.jpg | Describe the main subject of this image. | Case 1: Computed tomography showing the growth with pressure on the trachea. |
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