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PMC1941740_F1_12804.jpg
What's the most prominent thing you notice in this picture?
Distribution of CD105 antigen in normal, non-tumor (TF and AT), and tumor tissues. A, Immunostaining for CD105 in normal tissues. B, Highlighted microvessels by CD105 in tumor tissues. C, Diffuse positive sinusoidal segments found in the surrounding of tumor. D, Diffuse positive HSECs in the surrounding of draining vei...
PMC1941740_F1_12800.jpg
Can you identify the primary element in this image?
Distribution of CD105 antigen in normal, non-tumor (TF and AT), and tumor tissues. A, Immunostaining for CD105 in normal tissues. B, Highlighted microvessels by CD105 in tumor tissues. C, Diffuse positive sinusoidal segments found in the surrounding of tumor. D, Diffuse positive HSECs in the surrounding of draining vei...
PMC1941740_F1_12801.jpg
What does this image primarily show?
Distribution of CD105 antigen in normal, non-tumor (TF and AT), and tumor tissues. A, Immunostaining for CD105 in normal tissues. B, Highlighted microvessels by CD105 in tumor tissues. C, Diffuse positive sinusoidal segments found in the surrounding of tumor. D, Diffuse positive HSECs in the surrounding of draining vei...
PMC1941740_F1_12803.jpg
What is the central feature of this picture?
Distribution of CD105 antigen in normal, non-tumor (TF and AT), and tumor tissues. A, Immunostaining for CD105 in normal tissues. B, Highlighted microvessels by CD105 in tumor tissues. C, Diffuse positive sinusoidal segments found in the surrounding of tumor. D, Diffuse positive HSECs in the surrounding of draining vei...
PMC1941740_F4_12806.jpg
What is the dominant medical problem in this image?
Distribution of HIF-1alpha antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for HIF-1alpha in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941740_F4_12805.jpg
Can you identify the primary element in this image?
Distribution of HIF-1alpha antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for HIF-1alpha in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941740_F4_12807.jpg
What key item or scene is captured in this photo?
Distribution of HIF-1alpha antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for HIF-1alpha in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941740_F5_12812.jpg
What's the most prominent thing you notice in this picture?
Distribution of VEGF antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for VEGF in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941740_F5_12809.jpg
What does this image primarily show?
Distribution of VEGF antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for VEGF in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941740_F5_12810.jpg
What is shown in this image?
Distribution of VEGF antigen in normal, non-tumor (TF and AT), and tumor tissues. Immunostaining for VEGF in HC (A), tumor tissues (B), the surrounding of tumor (C), and portal area of non-tumor tissues (D). The signals were detected by DAB staining. Magnification: ×200.
PMC1941749_ppat-0030112-g007_12813.jpg
What is the main focus of this visual representation?
Detection of IFN-β and Phosphorylated STAT1 in Lung of SARS-CoV–Infected Macaques Using Immunohistochemistry(A) Lack of IFN-β expression in lungs of mock-infected macaques (magnification 40×) and (B, C) expression of IFN-β (red) in lungs of SARS-CoV–infected macaques at day 1 post infection (40× [B] and 100× [C], arrow...
PMC1941749_ppat-0030112-g007_12815.jpg
What's the most prominent thing you notice in this picture?
Detection of IFN-β and Phosphorylated STAT1 in Lung of SARS-CoV–Infected Macaques Using Immunohistochemistry(A) Lack of IFN-β expression in lungs of mock-infected macaques (magnification 40×) and (B, C) expression of IFN-β (red) in lungs of SARS-CoV–infected macaques at day 1 post infection (40× [B] and 100× [C], arrow...
PMC1941749_ppat-0030112-g007_12817.jpg
What is the core subject represented in this visual?
Detection of IFN-β and Phosphorylated STAT1 in Lung of SARS-CoV–Infected Macaques Using Immunohistochemistry(A) Lack of IFN-β expression in lungs of mock-infected macaques (magnification 40×) and (B, C) expression of IFN-β (red) in lungs of SARS-CoV–infected macaques at day 1 post infection (40× [B] and 100× [C], arrow...
PMC1941749_ppat-0030112-g007_12816.jpg
What is the core subject represented in this visual?
Detection of IFN-β and Phosphorylated STAT1 in Lung of SARS-CoV–Infected Macaques Using Immunohistochemistry(A) Lack of IFN-β expression in lungs of mock-infected macaques (magnification 40×) and (B, C) expression of IFN-β (red) in lungs of SARS-CoV–infected macaques at day 1 post infection (40× [B] and 100× [C], arrow...
PMC1941749_ppat-0030112-g007_12818.jpg
What is the focal point of this photograph?
Detection of IFN-β and Phosphorylated STAT1 in Lung of SARS-CoV–Infected Macaques Using Immunohistochemistry(A) Lack of IFN-β expression in lungs of mock-infected macaques (magnification 40×) and (B, C) expression of IFN-β (red) in lungs of SARS-CoV–infected macaques at day 1 post infection (40× [B] and 100× [C], arrow...
PMC1941751_pgen-0030132-g002_12820.jpg
What is the dominant medical problem in this image?
Hypersensitivity of Atmus81 Mutants to MMS, Cisplatin, and Gamma Radiation(A) Wild-type Col-0 (rows one and three) and mutant Atmus81/Atmus81 (rows two and four) were subjected to a gradient (0–75 ppm) of MMS. The photograph was taken after 20 d. The wild-type plants can grow at each concentration tested while the muta...
PMC1941751_pgen-0030132-g002_12819.jpg
What is the dominant medical problem in this image?
Hypersensitivity of Atmus81 Mutants to MMS, Cisplatin, and Gamma Radiation(A) Wild-type Col-0 (rows one and three) and mutant Atmus81/Atmus81 (rows two and four) were subjected to a gradient (0–75 ppm) of MMS. The photograph was taken after 20 d. The wild-type plants can grow at each concentration tested while the muta...
PMC1941754_pgen-0030130-g003_12827.jpg
What is the principal component of this image?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12825.jpg
What does this image primarily show?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12839.jpg
What is the focal point of this photograph?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12832.jpg
What is the main focus of this visual representation?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12826.jpg
What is being portrayed in this visual content?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12824.jpg
What is the main focus of this visual representation?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12829.jpg
What is the core subject represented in this visual?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12834.jpg
Describe the main subject of this image.
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12837.jpg
What is the principal component of this image?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12830.jpg
What is the central feature of this picture?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12836.jpg
What is the principal component of this image?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12822.jpg
What does this image primarily show?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941754_pgen-0030130-g003_12838.jpg
What is being portrayed in this visual content?
Histology of Mutant GonadsAll are hematoxylin/eosin-stained paraffin sections. Testes are from 6-wk-old males, except as indicated below.(A) Wild-type 25-d-old ovary.(B) Trip13Gt /Gt 25-d-old ovary, showing dysgenesis from an absence of oocytes.(C) Trip13Gt/+ 2-d-old control ovary. Arrows point to oocytes in newly form...
PMC1941843_F7_12843.jpg
What is the focal point of this photograph?
Visualization of interaction between DNA and cell membrane. Visualization of interaction between DNA and cell membrane after single polarity electric field protocol (a) and both polarities electric field protocol (b). Photos of phase contrast (1) and fluorescence (2) images were taken under inverted fluorescence micros...
PMC1941843_F7_12844.jpg
What can you see in this picture?
Visualization of interaction between DNA and cell membrane. Visualization of interaction between DNA and cell membrane after single polarity electric field protocol (a) and both polarities electric field protocol (b). Photos of phase contrast (1) and fluorescence (2) images were taken under inverted fluorescence micros...
PMC1941843_F8_12850.jpg
What is the focal point of this photograph?
Shading effect. Photos of phase contrast (a) and fluorescence (b) images were taken under inverted fluorescence microscope. Symbolic picture (c) was made for better representation of the observed shading effect. Drawn shapes represent cells and black areas represent regions of permeabilized membrane where DNA interacts...
PMC1941843_F8_12848.jpg
What is the dominant medical problem in this image?
Shading effect. Photos of phase contrast (a) and fluorescence (b) images were taken under inverted fluorescence microscope. Symbolic picture (c) was made for better representation of the observed shading effect. Drawn shapes represent cells and black areas represent regions of permeabilized membrane where DNA interacts...
PMC1942081_pone-0000765-g006_12854.jpg
What is the core subject represented in this visual?
Structure of the nanoparticles.Transmission electron microscopy pictures of (A) VLPs, (B) in vitro packaged nanoparticles, and (C) wild type SV40. Samples were adsorbed onto formvar-carbon-coated copper grids and stained with 1% sodium phosphotungstate, pH 7.0. The samples were viewed in a Philips CM-12 electron micros...
PMC1942081_pone-0000765-g006_12852.jpg
What does this image primarily show?
Structure of the nanoparticles.Transmission electron microscopy pictures of (A) VLPs, (B) in vitro packaged nanoparticles, and (C) wild type SV40. Samples were adsorbed onto formvar-carbon-coated copper grids and stained with 1% sodium phosphotungstate, pH 7.0. The samples were viewed in a Philips CM-12 electron micros...
PMC1942081_pone-0000765-g006_12853.jpg
What is the dominant medical problem in this image?
Structure of the nanoparticles.Transmission electron microscopy pictures of (A) VLPs, (B) in vitro packaged nanoparticles, and (C) wild type SV40. Samples were adsorbed onto formvar-carbon-coated copper grids and stained with 1% sodium phosphotungstate, pH 7.0. The samples were viewed in a Philips CM-12 electron micros...
PMC1945014_pone-0000779-g003_12859.jpg
What can you see in this picture?
Double staining images after spectral imaging.A: FOXP3 (green) and CD3 (red) in atherosclerotic intima. Nuclei are depicted in blue. Inset shows double stained cell. Note nuclear staining of transcription factor FOXP3 and cytoplasmatic CD3 positivity; B: GITR (green) and CD3 (red) in atherosclerotic intima. Inset shows...
PMC1945014_pone-0000779-g003_12857.jpg
What does this image primarily show?
Double staining images after spectral imaging.A: FOXP3 (green) and CD3 (red) in atherosclerotic intima. Nuclei are depicted in blue. Inset shows double stained cell. Note nuclear staining of transcription factor FOXP3 and cytoplasmatic CD3 positivity; B: GITR (green) and CD3 (red) in atherosclerotic intima. Inset shows...
PMC1945014_pone-0000779-g003_12860.jpg
What is the central feature of this picture?
Double staining images after spectral imaging.A: FOXP3 (green) and CD3 (red) in atherosclerotic intima. Nuclei are depicted in blue. Inset shows double stained cell. Note nuclear staining of transcription factor FOXP3 and cytoplasmatic CD3 positivity; B: GITR (green) and CD3 (red) in atherosclerotic intima. Inset shows...
PMC1945014_pone-0000779-g003_12855.jpg
Can you identify the primary element in this image?
Double staining images after spectral imaging.A: FOXP3 (green) and CD3 (red) in atherosclerotic intima. Nuclei are depicted in blue. Inset shows double stained cell. Note nuclear staining of transcription factor FOXP3 and cytoplasmatic CD3 positivity; B: GITR (green) and CD3 (red) in atherosclerotic intima. Inset shows...
PMC1945014_pone-0000779-g003_12856.jpg
What is shown in this image?
Double staining images after spectral imaging.A: FOXP3 (green) and CD3 (red) in atherosclerotic intima. Nuclei are depicted in blue. Inset shows double stained cell. Note nuclear staining of transcription factor FOXP3 and cytoplasmatic CD3 positivity; B: GITR (green) and CD3 (red) in atherosclerotic intima. Inset shows...
PMC1945015_pone-0000772-g010_12861.jpg
What's the most prominent thing you notice in this picture?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12868.jpg
What is shown in this image?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12862.jpg
What's the most prominent thing you notice in this picture?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12866.jpg
What is the dominant medical problem in this image?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12865.jpg
What stands out most in this visual?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12867.jpg
What key item or scene is captured in this photo?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945015_pone-0000772-g010_12863.jpg
What does this image primarily show?
Eye Pathology.Light micrographs showing pathology from normal (A, F, H) and MPS IIIB (B–D, E, G, I) mouse retinas (A–E), sclera (F, G), and ciliary bodies (H, I). (A) Normal histology from a 4-week old wild type mouse retina is shown and is indistinguishable from older wild type retinas at 45 weeks. (B) In the 8-week o...
PMC1945016_pone-0000763-g003_12878.jpg
Can you identify the primary element in this image?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945016_pone-0000763-g003_12870.jpg
What's the most prominent thing you notice in this picture?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945016_pone-0000763-g003_12877.jpg
What is the principal component of this image?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945016_pone-0000763-g003_12879.jpg
What can you see in this picture?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945016_pone-0000763-g003_12871.jpg
What is being portrayed in this visual content?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945016_pone-0000763-g003_12881.jpg
What's the most prominent thing you notice in this picture?
Variation in histone H4 acetylation and methylation in mouse epidermis and effects of Myc activation.(A–C, E–G, I–K) Immunofluorescence staining of whole mounts of wild-type (A–C, F, G, K) and 4OHT treated K14MycER transgenic (E,I, J) epidermis with antibodies to (green) H4Ac (A–C, E), H4monoK20 (F, G, I, J) and H4triK...
PMC1945019_F5_12884.jpg
What is shown in this image?
LCNK SCC, A- Fibres cells (arrow) and koilocytes (arrow head), Pap stain, × 400. B- Marked nuclear pleomorphism and hyperchromasia and heavy neutrophilic infiltrate, Pap stain, × 400. C- Corresponding biopsy: islands of neoplastic cells surrounded by heavy neutrophilic infiltrate, H&E, ×10
PMC1945019_F5_12886.jpg
What is being portrayed in this visual content?
LCNK SCC, A- Fibres cells (arrow) and koilocytes (arrow head), Pap stain, × 400. B- Marked nuclear pleomorphism and hyperchromasia and heavy neutrophilic infiltrate, Pap stain, × 400. C- Corresponding biopsy: islands of neoplastic cells surrounded by heavy neutrophilic infiltrate, H&E, ×10
PMC1945019_F5_12885.jpg
What stands out most in this visual?
LCNK SCC, A- Fibres cells (arrow) and koilocytes (arrow head), Pap stain, × 400. B- Marked nuclear pleomorphism and hyperchromasia and heavy neutrophilic infiltrate, Pap stain, × 400. C- Corresponding biopsy: islands of neoplastic cells surrounded by heavy neutrophilic infiltrate, H&E, ×10
PMC1945019_F7_12888.jpg
What is the dominant medical problem in this image?
EGD, A- EGD, ISH, pan HPV probe, ×10. B- Higher power magnification showing variable degree of intensity with severe intensity in the middle zone, ×40.
PMC1945025_F2_12892.jpg
What is the principal component of this image?
(a). Plain radiograph of a 74-year-old woman. The radiograph reveals a pathologic fracture at the diaphysis of the left tibia due to an osteolytic lesion in the medullary cavity. (b). T1-weighted magnetic resonance image showing several tibial lesions that are eccentric, oval and associated with clinically significant ...
PMC1945025_F3_12889.jpg
What is the core subject represented in this visual?
Magnetic resonance image of lumbosacral spine showing a compression fracture of L5 of posterior bulging contour with enhancement and epidural soft tissue mass over the anterior epidural space with marked compression of the thecal sac.
PMC1945027_F1_12930.jpg
What is the core subject represented in this visual?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F1_12936.jpg
What is the main focus of this visual representation?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F1_12935.jpg
What is the focal point of this photograph?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F1_12934.jpg
What is being portrayed in this visual content?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F1_12931.jpg
What is the focal point of this photograph?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F1_12932.jpg
What is the focal point of this photograph?
MRI of normal mouse prostate. Prostates from year old C57/BL6 mice were imaged (FOV = 35 mm2, 256 × 256 pixels). A: Images of b3m3 on three different days (A1, A2, A3). B: b3m2, C: b4m1, D: b2m3. Second column (A1'-D') shows the prostate outlined in white. Each image is the central 8.75 mm square (64 × 64 pixels) porti...
PMC1945027_F2_12898.jpg
What object or scene is depicted here?
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F2_12895.jpg
What is the principal component of this image?
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F2_12894.jpg
What's the most prominent thing you notice in this picture?
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F2_12901.jpg
Describe the main subject of this image.
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F2_12897.jpg
What can you see in this picture?
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F2_12899.jpg
What stands out most in this visual?
MRI of prostate following castration. Mouse b2m3. A: 1 day; B: 3 days; C: 8 days; and D: 10 days. The second column (A'-D') shows the prostate outlined in white as in Figure 1. E: Regression of the prostates of three individual mice. Square symbols represent the volume of the prostate of b2m3, circles represent b5m1, a...
PMC1945027_F3_12905.jpg
What's the most prominent thing you notice in this picture?
CHESS suppresses fat signal artifact and facilitates discrimination between ventral and dorsal-lateral lobes. A: T2- weighted MRI. A': Magnification of the central 64 × 64 pixel square, indicated by the white box in A. White arrow in A and black arrows in A' illustrate the shift of the signal derived from fat. The loca...
PMC1945027_F3_12903.jpg
What is the core subject represented in this visual?
CHESS suppresses fat signal artifact and facilitates discrimination between ventral and dorsal-lateral lobes. A: T2- weighted MRI. A': Magnification of the central 64 × 64 pixel square, indicated by the white box in A. White arrow in A and black arrows in A' illustrate the shift of the signal derived from fat. The loca...
PMC1945027_F3_12904.jpg
What is the core subject represented in this visual?
CHESS suppresses fat signal artifact and facilitates discrimination between ventral and dorsal-lateral lobes. A: T2- weighted MRI. A': Magnification of the central 64 × 64 pixel square, indicated by the white box in A. White arrow in A and black arrows in A' illustrate the shift of the signal derived from fat. The loca...
PMC1945027_F3_12906.jpg
What's the most prominent thing you notice in this picture?
CHESS suppresses fat signal artifact and facilitates discrimination between ventral and dorsal-lateral lobes. A: T2- weighted MRI. A': Magnification of the central 64 × 64 pixel square, indicated by the white box in A. White arrow in A and black arrows in A' illustrate the shift of the signal derived from fat. The loca...
PMC1945027_F4_12913.jpg
What is shown in this image?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12910.jpg
What can you see in this picture?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12914.jpg
What is the dominant medical problem in this image?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12907.jpg
What object or scene is depicted here?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12915.jpg
What is the principal component of this image?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12909.jpg
What is the principal component of this image?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F4_12911.jpg
What is the central feature of this picture?
MR-CHESS imaging of prostate involution. Prostate of b6m1 following castration A: 1 day; B: 3 days; C: 8 days; D: 10 days. Second column (A'-D') shows the VP outlined in white and the DLP outlined in black. Each image is the central 7.5 mm square (64 × 64 pixels) portion of the complete MRI image (FOV = 30 mm2, 256 × 2...
PMC1945027_F5_12925.jpg
Describe the main subject of this image.
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12921.jpg
What is being portrayed in this visual content?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12926.jpg
What is the dominant medical problem in this image?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12919.jpg
What object or scene is depicted here?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12918.jpg
What is shown in this image?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12924.jpg
What is being portrayed in this visual content?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12922.jpg
What is the core subject represented in this visual?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12927.jpg
What is the core subject represented in this visual?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945027_F5_12923.jpg
What is the main focus of this visual representation?
MR-CHESS imaging of prostate re-growth during androgen supplementation of castrated mice. Prostate from b7m1 following castration and DHT treatment. A: day 0 (16 days following castration); B: 2 days DHT treatment; C: 4 days DHT treatment; D: 9 days DHT treatment; E: 12 days DHT treatment; F: 16 days DHT treatment. Sec...
PMC1945040_pbio-0050220-g001_12938.jpg
What is the main focus of this visual representation?
FHV Protein A Is Localized in Virus-Induced Mitochondrial Spherules(A and B) Examples of anti-protein A immunogold labeling of mitochondrial spherules in FHV-infected cells. Cells were fixed in 4% paraformaldehyde and 0.2% glutaraldehyde, postfixed in 0.1% osmium, dehydrated and embedded in LR Gold resin, sectioned and...
PMC1945040_pbio-0050220-g001_12937.jpg
What's the most prominent thing you notice in this picture?
FHV Protein A Is Localized in Virus-Induced Mitochondrial Spherules(A and B) Examples of anti-protein A immunogold labeling of mitochondrial spherules in FHV-infected cells. Cells were fixed in 4% paraformaldehyde and 0.2% glutaraldehyde, postfixed in 0.1% osmium, dehydrated and embedded in LR Gold resin, sectioned and...
PMC1945040_pbio-0050220-g007_12940.jpg
Can you identify the primary element in this image?
Modeling of FHV Transmembrane Protein A into a Spherule(A) 3-D map of a single spherule where half of the membrane has been removed to show the interior. As in Figure 4, the spherule membrane is white and the contiguous outer mitochondrial membrane is blue.(B) Schematic of likely protein A organization within a spherul...
PMC1945040_pbio-0050220-g007_12942.jpg
Can you identify the primary element in this image?
Modeling of FHV Transmembrane Protein A into a Spherule(A) 3-D map of a single spherule where half of the membrane has been removed to show the interior. As in Figure 4, the spherule membrane is white and the contiguous outer mitochondrial membrane is blue.(B) Schematic of likely protein A organization within a spherul...
PMC1945041_pbio-0050221-g003_12954.jpg
What is the main focus of this visual representation?
Hem-1 Waves Result from Propagated Recruitment and Release of Hem-1, Not a Moving Front of Translocated Protein(A) Control Hem-1-YFP–expressing cells (pre-polarized in uniform chemoattractant) rapidly recover fluorescence intensity following photobleaching, indicating rapid exchange of membrane-bound Hem-1 with the cyt...
PMC1945041_pbio-0050221-g003_12957.jpg
What object or scene is depicted here?
Hem-1 Waves Result from Propagated Recruitment and Release of Hem-1, Not a Moving Front of Translocated Protein(A) Control Hem-1-YFP–expressing cells (pre-polarized in uniform chemoattractant) rapidly recover fluorescence intensity following photobleaching, indicating rapid exchange of membrane-bound Hem-1 with the cyt...
PMC1945041_pbio-0050221-g003_12953.jpg
What is the focal point of this photograph?
Hem-1 Waves Result from Propagated Recruitment and Release of Hem-1, Not a Moving Front of Translocated Protein(A) Control Hem-1-YFP–expressing cells (pre-polarized in uniform chemoattractant) rapidly recover fluorescence intensity following photobleaching, indicating rapid exchange of membrane-bound Hem-1 with the cyt...