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PMC1937017_pcbi-0030155-g010_12639.jpg
What can you see in this picture?
No Decondensation of Chromatin following 5 Gy of Low LETHeLa cells transfected with H1.2-GFP (see Materials and Methods) were imaged before and after exposure to 5 Gy of X-rays (A). Control cells that were not exposed to X-rays were also monitored (B). Intensity correlation within the nucleus (contour shown in blue on ...
PMC1937022_pone-0000754-g002_12662.jpg
What is the core subject represented in this visual?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12648.jpg
What is the dominant medical problem in this image?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12661.jpg
What is the dominant medical problem in this image?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12647.jpg
Can you identify the primary element in this image?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12664.jpg
What can you see in this picture?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12651.jpg
What is the core subject represented in this visual?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12660.jpg
Can you identify the primary element in this image?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12649.jpg
What can you see in this picture?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12654.jpg
What key item or scene is captured in this photo?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1937022_pone-0000754-g002_12656.jpg
What is the principal component of this image?
Expression of Hoxd genes in catshark pectoral fins.Stages of development indicated in lower right corners of each panel. (A–D) Whole mount in situ hybridizations showing expression of Hoxd9 (A), Hoxd10 (B), Hoxd12 (C) and Hoxd13 (D). Pect, Pectoral fin bud; Cl, cloaca. Note anterior expansion of Hoxd12 and Hoxd13 in di...
PMC1939707_F1_12669.jpg
What's the most prominent thing you notice in this picture?
CECT (top left), early(top right) and delayed phase (bottom) FDG-PET/CT fusion images of a 46 year old male with lung carcinoma showing delayed accumulation of FDG in a segment 7 metastatic lesion.
PMC1939707_F1_12667.jpg
What can you see in this picture?
CECT (top left), early(top right) and delayed phase (bottom) FDG-PET/CT fusion images of a 46 year old male with lung carcinoma showing delayed accumulation of FDG in a segment 7 metastatic lesion.
PMC1939707_F2_12672.jpg
What is being portrayed in this visual content?
Early (top left) and delayed phase (top right) FDG-PET/CT of a 54 year old female with metastatic colorectal carcinoma showing a segment 6 lesion not seen on CECT performed on the same date (bottom left) but surfacing 6 months later (bottom right).
PMC1939707_F2_12673.jpg
What object or scene is depicted here?
Early (top left) and delayed phase (top right) FDG-PET/CT of a 54 year old female with metastatic colorectal carcinoma showing a segment 6 lesion not seen on CECT performed on the same date (bottom left) but surfacing 6 months later (bottom right).
PMC1939707_F2_12670.jpg
Describe the main subject of this image.
Early (top left) and delayed phase (top right) FDG-PET/CT of a 54 year old female with metastatic colorectal carcinoma showing a segment 6 lesion not seen on CECT performed on the same date (bottom left) but surfacing 6 months later (bottom right).
PMC1939707_F2_12671.jpg
What is the dominant medical problem in this image?
Early (top left) and delayed phase (top right) FDG-PET/CT of a 54 year old female with metastatic colorectal carcinoma showing a segment 6 lesion not seen on CECT performed on the same date (bottom left) but surfacing 6 months later (bottom right).
PMC1939707_F3_12665.jpg
What is the main focus of this visual representation?
CECT (left) and delayed phase FDG-PET/CT fusion images (right) of a 42 year old female with lung carcinoma showing FDG uptake in periportal/peripancreatic lymph nodes not clearly demonstrated on CECT.
PMC1939707_F3_12666.jpg
Can you identify the primary element in this image?
CECT (left) and delayed phase FDG-PET/CT fusion images (right) of a 42 year old female with lung carcinoma showing FDG uptake in periportal/peripancreatic lymph nodes not clearly demonstrated on CECT.
PMC1939711_F6_12675.jpg
What is the core subject represented in this visual?
Detection of RASSF1A protein in clear cell RCC and control cell lines. Paraffin-embedded tissue samples obtained from renal tumor and paired normal tissues were analyzed for presence of RASSF1A protein using immunohistochemistry (counterstaining hematoxylin). a. Immunohistochemical positive control: CaSki cell line dem...
PMC1939711_F6_12679.jpg
What is being portrayed in this visual content?
Detection of RASSF1A protein in clear cell RCC and control cell lines. Paraffin-embedded tissue samples obtained from renal tumor and paired normal tissues were analyzed for presence of RASSF1A protein using immunohistochemistry (counterstaining hematoxylin). a. Immunohistochemical positive control: CaSki cell line dem...
PMC1939711_F6_12674.jpg
What is the main focus of this visual representation?
Detection of RASSF1A protein in clear cell RCC and control cell lines. Paraffin-embedded tissue samples obtained from renal tumor and paired normal tissues were analyzed for presence of RASSF1A protein using immunohistochemistry (counterstaining hematoxylin). a. Immunohistochemical positive control: CaSki cell line dem...
PMC1939711_F6_12678.jpg
What object or scene is depicted here?
Detection of RASSF1A protein in clear cell RCC and control cell lines. Paraffin-embedded tissue samples obtained from renal tumor and paired normal tissues were analyzed for presence of RASSF1A protein using immunohistochemistry (counterstaining hematoxylin). a. Immunohistochemical positive control: CaSki cell line dem...
PMC1939711_F6_12677.jpg
What can you see in this picture?
Detection of RASSF1A protein in clear cell RCC and control cell lines. Paraffin-embedded tissue samples obtained from renal tumor and paired normal tissues were analyzed for presence of RASSF1A protein using immunohistochemistry (counterstaining hematoxylin). a. Immunohistochemical positive control: CaSki cell line dem...
PMC1939715_F1_12681.jpg
What stands out most in this visual?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F1_12687.jpg
What is the principal component of this image?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F1_12685.jpg
What is the dominant medical problem in this image?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F1_12680.jpg
What key item or scene is captured in this photo?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F1_12686.jpg
What is being portrayed in this visual content?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F1_12684.jpg
What key item or scene is captured in this photo?
The localization of prolactin receptor in the liver was evaluated by immunohistochemistry (scale bar = 50 μm) in liver sections from normal and BDL female and male rats. Bile ducts from normal and BDL female and male rats express these receptors (arrows). No immunohistochemical reaction was observed when a consecutive ...
PMC1939715_F8_12690.jpg
What does this image primarily show?
Immunohistochemistry for prolactin in liver sections of normal and BDL female rats shows that intrahepatic bile ducts express the protein for prolactin (arrows). Bar = 50 μm.
PMC1939715_F8_12689.jpg
Describe the main subject of this image.
Immunohistochemistry for prolactin in liver sections of normal and BDL female rats shows that intrahepatic bile ducts express the protein for prolactin (arrows). Bar = 50 μm.
PMC1939715_F8_12688.jpg
What does this image primarily show?
Immunohistochemistry for prolactin in liver sections of normal and BDL female rats shows that intrahepatic bile ducts express the protein for prolactin (arrows). Bar = 50 μm.
PMC1939831_F1_12696.jpg
Can you identify the primary element in this image?
HIFU exposure system and B-mode guidance. (A) Diagram of the in vivo HIFU exposure setup. (B) Alignment of the mouse tumor with the focus of the HIFU transducer was aided by B-mode ultrasound imaging.
PMC1939831_F3_12693.jpg
What's the most prominent thing you notice in this picture?
Ultrasound imaging of HIFU-induced cavitation. Time progression of a mechanical HIFU-exposure with B-mode ultrasound imaging. Bright hyperechoic spots generated by HIFU indicate regions of cavitation.
PMC1939831_F3_12692.jpg
What is the focal point of this photograph?
Ultrasound imaging of HIFU-induced cavitation. Time progression of a mechanical HIFU-exposure with B-mode ultrasound imaging. Bright hyperechoic spots generated by HIFU indicate regions of cavitation.
PMC1939831_F3_12695.jpg
What is the dominant medical problem in this image?
Ultrasound imaging of HIFU-induced cavitation. Time progression of a mechanical HIFU-exposure with B-mode ultrasound imaging. Bright hyperechoic spots generated by HIFU indicate regions of cavitation.
PMC1939849_F1_12698.jpg
What is the core subject represented in this visual?
(A) Abdominal computed tomography (CT) revealed enhanced thickness of the gastric wall and multiple liver metastases. (B) Gastroscopy revealed a Borrmann type III tumor on the lesser curvature in the midportion of the stomach.
PMC1939849_F1_12699.jpg
What is the focal point of this photograph?
(A) Abdominal computed tomography (CT) revealed enhanced thickness of the gastric wall and multiple liver metastases. (B) Gastroscopy revealed a Borrmann type III tumor on the lesser curvature in the midportion of the stomach.
PMC1939849_F3_12701.jpg
What is the central feature of this picture?
(A) Enhanced CT revealed that liver metastases had decreased in size following initial therapy. (B) After 5 months of treatment, multiple liver metastases reappeared in segments 1, 3, and 5. (C) Following second-line treatment with 5-FU/paclitaxel and paclitaxel monotherapy, liver metastases either regressed or disappe...
PMC1939849_F3_12700.jpg
What is the main focus of this visual representation?
(A) Enhanced CT revealed that liver metastases had decreased in size following initial therapy. (B) After 5 months of treatment, multiple liver metastases reappeared in segments 1, 3, and 5. (C) Following second-line treatment with 5-FU/paclitaxel and paclitaxel monotherapy, liver metastases either regressed or disappe...
PMC1939849_F3_12702.jpg
What stands out most in this visual?
(A) Enhanced CT revealed that liver metastases had decreased in size following initial therapy. (B) After 5 months of treatment, multiple liver metastases reappeared in segments 1, 3, and 5. (C) Following second-line treatment with 5-FU/paclitaxel and paclitaxel monotherapy, liver metastases either regressed or disappe...
PMC1939867_F2_12704.jpg
What stands out most in this visual?
The left panel shows an overlay of two left ventricular angiography images taken at end diastole and end systole. The light contrasted area shows the end-diastolic volume, whereas the dark shaded area corresponds to end-systole. Apical akinesia and inferior hypokinesia due to remote myocardial infarction can be identif...
PMC1939868_F1_12705.jpg
What is the focal point of this photograph?
The left panel shows a MRI cardiac short axis scan (slice thickness 6mm). The middle panel shows a triangulated and remeshed surface model of individual cardiac anatomy (LV=left ventricle; RV=right ventricle; RVOT=right ventricular outflow tract). The right panel shows the fusion of MRI data and the individual cardiac ...
PMC1939868_F1_12707.jpg
What is shown in this image?
The left panel shows a MRI cardiac short axis scan (slice thickness 6mm). The middle panel shows a triangulated and remeshed surface model of individual cardiac anatomy (LV=left ventricle; RV=right ventricle; RVOT=right ventricular outflow tract). The right panel shows the fusion of MRI data and the individual cardiac ...
PMC1939872_F2_12709.jpg
What does this image primarily show?
Parasternal transthoracic echocardiographic view demonstrating and confirming the ventricular pacing lead going from the right atrium to the right ventricle with its tip located in the apical position.
PMC1939878_pone-0000749-g006_12710.jpg
What key item or scene is captured in this photo?
Chloroplast.(A) 7.2-nm thick slice through a non-dividing cell. The starch granule (white arrow) has suffered damage from the electron beam. Besides it are two dark granules (white arrowhead). (B) Above: Enlarged view of the boxed area in panel A. The three thylakoid membranes (black arrowhead) can be seen forming a st...
PMC1939878_pone-0000749-g006_12711.jpg
What does this image primarily show?
Chloroplast.(A) 7.2-nm thick slice through a non-dividing cell. The starch granule (white arrow) has suffered damage from the electron beam. Besides it are two dark granules (white arrowhead). (B) Above: Enlarged view of the boxed area in panel A. The three thylakoid membranes (black arrowhead) can be seen forming a st...
PMC1939878_pone-0000749-g006_12713.jpg
Can you identify the primary element in this image?
Chloroplast.(A) 7.2-nm thick slice through a non-dividing cell. The starch granule (white arrow) has suffered damage from the electron beam. Besides it are two dark granules (white arrowhead). (B) Above: Enlarged view of the boxed area in panel A. The three thylakoid membranes (black arrowhead) can be seen forming a st...
PMC1939878_pone-0000749-g006_12712.jpg
What stands out most in this visual?
Chloroplast.(A) 7.2-nm thick slice through a non-dividing cell. The starch granule (white arrow) has suffered damage from the electron beam. Besides it are two dark granules (white arrowhead). (B) Above: Enlarged view of the boxed area in panel A. The three thylakoid membranes (black arrowhead) can be seen forming a st...
PMC1939878_pone-0000749-g013_12716.jpg
What object or scene is depicted here?
Ribosome-like complexes.(A) Three cells (shown in panels D–F of Figure 3) were searched for ribosome-like particles, and the resulting local-normalized cross-correlation coefficients are plotted from best to worst from left to right. There were fewer total positions ranked in cell “3D” because its cytoplasm was smaller...
PMC1939878_pone-0000749-g013_12714.jpg
What stands out most in this visual?
Ribosome-like complexes.(A) Three cells (shown in panels D–F of Figure 3) were searched for ribosome-like particles, and the resulting local-normalized cross-correlation coefficients are plotted from best to worst from left to right. There were fewer total positions ranked in cell “3D” because its cytoplasm was smaller...
PMC1939883_pbio-0050210-g001_12728.jpg
What object or scene is depicted here?
Myosin VI Constructs and Their Association with UCV(A) Cartoon depictions of the sequences for full-length myosin VI with TD in blue and CBD in orange, the myosin VI CBD containing 17 amino acids of the myosin VI TD (denoted simply as the CBD), and CBD with the addition of an N-terminal leucine zipper (GCN4-CBD).(B) Ca...
PMC1939883_pbio-0050210-g001_12732.jpg
What's the most prominent thing you notice in this picture?
Myosin VI Constructs and Their Association with UCV(A) Cartoon depictions of the sequences for full-length myosin VI with TD in blue and CBD in orange, the myosin VI CBD containing 17 amino acids of the myosin VI TD (denoted simply as the CBD), and CBD with the addition of an N-terminal leucine zipper (GCN4-CBD).(B) Ca...
PMC1940036_fig4_12761.jpg
Describe the main subject of this image.
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12749.jpg
What is being portrayed in this visual content?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12754.jpg
What is the central feature of this picture?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12752.jpg
What does this image primarily show?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12763.jpg
What is the central feature of this picture?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12750.jpg
What is the central feature of this picture?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12764.jpg
What is the focal point of this photograph?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12751.jpg
What is being portrayed in this visual content?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig4_12756.jpg
What is the core subject represented in this visual?
mbl Mutants Have Parapineal Migration Defects and Bilaterally Symmetric Habenulae(A–H and A′–H′) Dorsal or frontal views of the epithalamus (anterior to the top) of (A, A′, D, and D′) 2-day-, (B and B′) 2.5-day-, (F and F′) 3-day-, and (E, E′, G, G′, H, and H′) 4-day-old wild-type and mbl mutant embryos. All markers us...
PMC1940036_fig5_12734.jpg
What key item or scene is captured in this photo?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12741.jpg
What is the principal component of this image?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12743.jpg
What is being portrayed in this visual content?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12744.jpg
Describe the main subject of this image.
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12746.jpg
What stands out most in this visual?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12736.jpg
What is the central feature of this picture?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12735.jpg
Describe the main subject of this image.
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12733.jpg
What stands out most in this visual?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12740.jpg
What object or scene is depicted here?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12738.jpg
Describe the main subject of this image.
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12739.jpg
What is the principal component of this image?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940036_fig5_12742.jpg
What is the central feature of this picture?
Epithalamic Asymmetries Are Largely Uncoupled in mbl Embryos(A–P) Dorsal views of (A–L) 4-day-old embryos derived from a mbltm213 × Tg(foxD3:GFP);Tg(lft1:GFP) incross were analyzed for (A, D, G, and J) parapineal migration and projections. The labeling performed and the genotype of the embryos analyzed are indicated on...
PMC1940315_F2_12768.jpg
What is the focal point of this photograph?
Intravitreal bevacizumab for proliferative diabetic retinopathy. A patient presented with proliferative diabetic retinopathy. Fundus photography (a) and fluorescein angiography (b) are shown. The patient was treated with intravitreal bevacizumab. Followup fluorescein angiography demonstrated improvement in angiographic...
PMC1940315_F2_12767.jpg
What does this image primarily show?
Intravitreal bevacizumab for proliferative diabetic retinopathy. A patient presented with proliferative diabetic retinopathy. Fundus photography (a) and fluorescein angiography (b) are shown. The patient was treated with intravitreal bevacizumab. Followup fluorescein angiography demonstrated improvement in angiographic...
PMC1940315_F2_12770.jpg
What is the main focus of this visual representation?
Intravitreal bevacizumab for proliferative diabetic retinopathy. A patient presented with proliferative diabetic retinopathy. Fundus photography (a) and fluorescein angiography (b) are shown. The patient was treated with intravitreal bevacizumab. Followup fluorescein angiography demonstrated improvement in angiographic...
PMC1940316_F2_12772.jpg
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Landmark-constrained conformal surface mapping of the cortex onto a sphere and construction of finite surface elements. (a) Cortical surface of a brain with defined landmarks showing the bilateral central sulci. (b) Landmark-constrained conformal mapping (CM) of the cortical mantel to the surface of a sphere. Constrain...
PMC1940316_F8_12773.jpg
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(a) Surface rendering of a patient's brain with an epileptic focus in the right temporal lobe. Finite cortical elements which represent abnormally decreased FDG PET tracer uptake are rendered as blue areas with dark blue representing the most severe decrease and with light blue representing the least severe decrease. T...
PMC1940316_F8_12774.jpg
What does this image primarily show?
(a) Surface rendering of a patient's brain with an epileptic focus in the right temporal lobe. Finite cortical elements which represent abnormally decreased FDG PET tracer uptake are rendered as blue areas with dark blue representing the most severe decrease and with light blue representing the least severe decrease. T...
PMC1940317_pone-0000669-g004_12777.jpg
What is the focal point of this photograph?
Extrusion of dsDNA produced by RT from ssDNA-NCp7 co-aggregates.Progression of DNA synthesis analyzed by TEM after 2 min. (A), 10 min. (B) and 40 min. (C) from reactions with ssDNA (5 nM), RT (50 nM) and NCp7 (3.4 µM). Disaggregation after 10 min. (B) appeared both at the periphery and within the aggregates. A few indi...
PMC1940317_pone-0000669-g004_12776.jpg
What is the main focus of this visual representation?
Extrusion of dsDNA produced by RT from ssDNA-NCp7 co-aggregates.Progression of DNA synthesis analyzed by TEM after 2 min. (A), 10 min. (B) and 40 min. (C) from reactions with ssDNA (5 nM), RT (50 nM) and NCp7 (3.4 µM). Disaggregation after 10 min. (B) appeared both at the periphery and within the aggregates. A few indi...
PMC1940317_pone-0000669-g004_12778.jpg
Describe the main subject of this image.
Extrusion of dsDNA produced by RT from ssDNA-NCp7 co-aggregates.Progression of DNA synthesis analyzed by TEM after 2 min. (A), 10 min. (B) and 40 min. (C) from reactions with ssDNA (5 nM), RT (50 nM) and NCp7 (3.4 µM). Disaggregation after 10 min. (B) appeared both at the periphery and within the aggregates. A few indi...
PMC1940317_pone-0000669-g004_12775.jpg
What can you see in this picture?
Extrusion of dsDNA produced by RT from ssDNA-NCp7 co-aggregates.Progression of DNA synthesis analyzed by TEM after 2 min. (A), 10 min. (B) and 40 min. (C) from reactions with ssDNA (5 nM), RT (50 nM) and NCp7 (3.4 µM). Disaggregation after 10 min. (B) appeared both at the periphery and within the aggregates. A few indi...
PMC1940319_pone-0000769-g003_12781.jpg
What's the most prominent thing you notice in this picture?
Validation of amplicons by FISH analysis on cell lines.Identification of increased copies of signals of the BAC clone RP11-165H19 mapped to 9p13.3 amplicon in cell line CWR22 and CWR22-Rv1 (A and B). C Optimal signal and lack of cross hybridization was verified using normal metaphase spreads showing two signals for eac...
PMC1941723_F1_12789.jpg
What is the main focus of this visual representation?
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941723_F1_12783.jpg
What stands out most in this visual?
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941723_F1_12787.jpg
What is being portrayed in this visual content?
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941723_F1_12788.jpg
What's the most prominent thing you notice in this picture?
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941723_F1_12784.jpg
What is the central feature of this picture?
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941723_F1_12785.jpg
Describe the main subject of this image.
Expression of pERK in the ipsilateral L4/5 dorsal horn after electrical stimuli was frequency-dependent. A-D: Photomicrographs show pERK expression in spinal cord of rats that received sham operations without electrical stimulation (A), or 16 pulses of 3 mA electrical stimulation at frequencies of 0.05 Hz (B), 0.5 Hz (...
PMC1941735_F2_12790.jpg
Can you identify the primary element in this image?
PET/CT fusion image on transaxial section demonstrates a hypermetabolic lesion (SUVmax : 8.2, Patient number 14) in the segment 6 of the liver (arrow) which could not be detected by GP. Final pathology was consistent with CRC metastasis.
PMC1941737_F1_12794.jpg
What is the focal point of this photograph?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941737_F1_12791.jpg
What is the principal component of this image?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941737_F1_12796.jpg
What is the core subject represented in this visual?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941737_F1_12793.jpg
What is the central feature of this picture?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941737_F1_12792.jpg
What's the most prominent thing you notice in this picture?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941737_F1_12795.jpg
What is the central feature of this picture?
Determination of the development stages enriched in immature precursors. Upper panel: Temporal evolution of lmo2 expression from the OB to LHF stages: initially expressed by most extra-embryonic mesodermal cells (A), lmo2 expression rapidly restricts to a smaller cell number at the EB stage (B). Lmo2 expression subsequ...
PMC1941740_F1_12802.jpg
What is the core subject represented in this visual?
Distribution of CD105 antigen in normal, non-tumor (TF and AT), and tumor tissues. A, Immunostaining for CD105 in normal tissues. B, Highlighted microvessels by CD105 in tumor tissues. C, Diffuse positive sinusoidal segments found in the surrounding of tumor. D, Diffuse positive HSECs in the surrounding of draining vei...