question stringlengths 84 268 | answer stringlengths 6 879 | reference_sequence stringlengths 4.1k 4.1k | mutated_sequence stringlengths 4.1k 4.1k | cleaned_pathogenicity stringclasses 2
values | __index_level_0__ int64 67 343k |
|---|---|---|---|---|---|
Gene MSH6 (mutS homolog 6) variant at chromosome position 47800812 on chromosome 2: benign or pathogenic? If pathogenic, what disease(s) is it associated with? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | TCTGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCA... | TCTGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCA... | pathogenic | 36,505 |
The genetic variant at chromosome 2, position 47800812, affecting gene MSH6 (mutS homolog 6): benign or pathogenic? Disease name(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | TCTGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCA... | TCTGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCA... | pathogenic | 36,506 |
Variant in gene MSH6 (mutS homolog 6), located at chromosome 2 position 47800814: benign or pathogenic? What disease(s) does it cause if pathogenic? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5', 'MSH6-related_disorder'] | TGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATG... | TGATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATG... | pathogenic | 36,507 |
Mutation at chromosome 2, position 47800815, within MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, indicate the disease(s). | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | GATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGA... | GATGTGGAATTTAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGA... | pathogenic | 36,508 |
Does the variant impacting MSH6 (mutS homolog 6) on chromosome 2, position 47800826, classify as benign or pathogenic? If pathogenic, what disease(s) is it associated with? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | TAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAAT... | TAAGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAAT... | pathogenic | 36,512 |
Does the chromosome 2 mutation at position 47800828 within gene MSH6 (mutS homolog 6) classify as benign or pathogenic? If pathogenic, indicate the related illness(es). | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | AGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGG... | AGCCAGACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGG... | pathogenic | 36,514 |
Does the chromosome 2 mutation at position 47800833 within gene MSH6 (mutS homolog 6) classify as benign or pathogenic? If pathogenic, indicate the related illness(es). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | GACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAA... | GACACTAAGGAGGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAA... | pathogenic | 36,516 |
Regarding the variant at chromosome 2 and position 47800844, affecting gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the associated illness(es)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGA... | GGAAGGAAGCAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGA... | pathogenic | 36,522 |
Benign or pathogenic: chromosome 2, position 47800853, gene MSH6 (mutS homolog 6) variant? Disease(s) if pathogenic? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATG... | CAGTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATG... | pathogenic | 36,526 |
Variant on chromosome 2, at position 47800855, affecting MSH6 (mutS homolog 6): is it benign or pathogenic? If pathogenic, specify the associated disease(s). | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAG... | GTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAG... | pathogenic | 36,529 |
Assess the variant on chromosome 2, position 47800855, impacting MSH6 (mutS homolog 6): is it benign or pathogenic? If pathogenic, specify the associated condition(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_1', 'Lynch_syndrome_5'] | GTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAG... | GTGATGAAATAAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAG... | pathogenic | 36,530 |
Evaluate if the mutation on chromosome 2 at position 47800865 in MSH6 (mutS homolog 6) is benign or pathogenic. Disease name(s) if pathogenic? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGA... | AAGCAGTGGAGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGA... | pathogenic | 36,534 |
Is the variant located on chromosome 2 at position 47800874, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, specify the disease(s) linked. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | AGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATC... | AGTGGGGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATC... | pathogenic | 36,537 |
A genetic variant on chromosome 2, position 47800879, affects the gene MSH6 (mutS homolog 6). Is this variant benign or pathogenic? If pathogenic, what disease(s) does it cause? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCC... | GGGATAGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCC... | pathogenic | 36,539 |
Is the genetic change at chromosome 2, position 47800884, within gene MSH6 (mutS homolog 6) benign or pathogenic? Name the disease(s) if pathogenic. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome'] | AGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTT... | AGTGAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTT... | pathogenic | 36,543 |
A genetic variant at chromosome 2, position 47800887, affecting gene MSH6 (mutS homolog 6)—is it benign or pathogenic? If pathogenic, identify the associated disorder(s). | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | GAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGA... | GAGAGTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGA... | pathogenic | 36,547 |
Clinically, how would you classify the variant at chromosome 2, position 47800891, gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, specify the associated illness(es). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Inherited_MMR_deficiency_(Lynch_syndrome)', 'Lynch_syndrome_5'] | GTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCA... | GTGAAGGCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCA... | pathogenic | 36,550 |
Variant chromosome 2, position 47800897, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACA... | GCCTGAACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACA... | pathogenic | 36,554 |
Considering the genetic mutation at chromosome 2, position 47800902, impacting MSH6 (mutS homolog 6): is it clinically benign or pathogenic? Name the associated disease(s) if pathogenic. | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTA... | AACAGCCCTGTCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTA... | pathogenic | 36,556 |
Regarding the variant found on chromosome 2 at position 47800912 in gene MSH6 (mutS homolog 6): is it benign or pathogenic? If pathogenic, identify the disease(s). | pathogenic; ['Lynch_syndrome_5'] | TCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAG... | TCAAAGTTGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAG... | pathogenic | 36,560 |
The mutation in gene MSH6 (mutS homolog 6) at chromosome 2, position 47800919—clinically benign or pathogenic? If pathogenic, identify the related disease(s). | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCC... | TGCTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCC... | pathogenic | 36,564 |
A genetic variant at chromosome 2, position 47800921, affecting gene MSH6 (mutS homolog 6)—is it benign or pathogenic? If pathogenic, identify the associated disorder(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTC... | CTCGAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTC... | pathogenic | 36,566 |
Clinical impact (benign or pathogenic) of the variant at chromosome 2, location 47800924, gene MSH6 (mutS homolog 6): what disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAAT... | GAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAAT... | pathogenic | 36,568 |
Variant in gene MSH6 (mutS homolog 6), located at chromosome 2 position 47800924: benign or pathogenic? What disease(s) does it cause if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | GAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAAT... | GAAAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAAT... | pathogenic | 36,569 |
Does the chromosome 2 mutation at position 47800926 within gene MSH6 (mutS homolog 6) classify as benign or pathogenic? If pathogenic, indicate the related illness(es). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | AAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTC... | AAGCGGAAGAGAATGGTGACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTC... | pathogenic | 36,571 |
Determine if the mutation at chromosome 2, position 47800943 in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, what disease(s) is associated? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGA... | GACTGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGA... | pathogenic | 36,576 |
Is the genetic variant on chromosome 2, position 47800946, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, what disease(s) is indicated? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5', 'MSH6-related_disorder'] | TGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGA... | TGGAAATGGCTCTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGA... | pathogenic | 36,578 |
Considering the variant on chromosome 2, location 47800957, involving gene MSH6 (mutS homolog 6), would you classify it as benign or pathogenic? What disease(s), if any, does a pathogenic variant indicate? | pathogenic; ['Lynch_syndrome'] | CTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAG... | CTCTTAAAAGGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAG... | pathogenic | 36,585 |
Is the variant located on chromosome 2 at position 47800966, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, specify the disease(s) linked. | pathogenic; ['Lynch_syndrome', 'Lynch_syndrome_5'] | GGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCT... | GGAAAAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCT... | pathogenic | 36,593 |
Regarding the variant at chromosome 2 and position 47800970, affecting gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the associated illness(es)? | pathogenic; ['Lynch_syndrome_5'] | AAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGA... | AAGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGA... | pathogenic | 36,595 |
Chromosome 2, position 47800971, gene MSH6 (mutS homolog 6): benign or pathogenic variant? If pathogenic, what are the linked illness(es)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAA... | AGCTCTAGGAAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAA... | pathogenic | 36,597 |
Mutation at chromosome 2, position 47800980, within MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, indicate the disease(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | AAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCT... | AAGGAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCT... | pathogenic | 36,602 |
Evaluate if the mutation on chromosome 2 at position 47800983 in MSH6 (mutS homolog 6) is benign or pathogenic. Disease name(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | GAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGT... | GAAACGCCCTCAGCCACCAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGT... | pathogenic | 36,603 |
Determine if the mutation at chromosome 2, position 47801000 in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, what disease(s) is associated? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGG... | CAAACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGG... | pathogenic | 36,610 |
A mutation at chromosome position 47801002 on chromosome 2 in gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, which disease(s) is it linked to? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGG... | AACAAGCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGG... | pathogenic | 36,614 |
Is the genetic variant on chromosome 2, position 47801007, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, what disease(s) is indicated? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATT... | GCAACTAGCATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATT... | pathogenic | 36,619 |
A genetic variant at chromosome 2, position 47801016, affecting gene MSH6 (mutS homolog 6)—is it benign or pathogenic? If pathogenic, identify the associated disorder(s). | pathogenic; ['Carcinoma_of_colon', 'Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | ATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCT... | ATTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCT... | pathogenic | 36,622 |
Evaluate this variant at chromosome 2, position 47801017, gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the disease connection(s)? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTG... | TTTCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTG... | pathogenic | 36,623 |
A genetic variant on chromosome 2, position 47801019, affects the gene MSH6 (mutS homolog 6). Is this variant benign or pathogenic? If pathogenic, what disease(s) does it cause? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | TCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTA... | TCATCAGAAACCAAGAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTA... | pathogenic | 36,625 |
The mutation in gene MSH6 (mutS homolog 6) at chromosome 2, position 47801033—clinically benign or pathogenic? If pathogenic, identify the related disease(s). | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | GAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTC... | GAATACTTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTC... | pathogenic | 36,628 |
Is the variant located on chromosome 2 at position 47801039, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, specify the disease(s) linked. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | TTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTG... | TTTGAGAGCTTTCTCTGCCCCTCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTG... | pathogenic | 36,631 |
Assess the clinical significance (benign or pathogenic) of the variant at chromosome 2, position 47801060, gene MSH6 (mutS homolog 6). What disease(s) is it linked to if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | TCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGG... | TCAAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGG... | pathogenic | 36,639 |
Variant chromosome 2, position 47801062, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | AAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTA... | AAAATTCTGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTA... | pathogenic | 36,640 |
Clinical impact (benign or pathogenic) of the variant at chromosome 2, location 47801069, gene MSH6 (mutS homolog 6): what disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | TGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGA... | TGAATCCCAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGA... | pathogenic | 36,645 |
Is the genetic variant on chromosome 2, position 47801076, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, what disease(s) is indicated? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAA... | CAAGCCCACGTTAGTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAA... | pathogenic | 36,649 |
Does the variant impacting MSH6 (mutS homolog 6) on chromosome 2, position 47801089, classify as benign or pathogenic? If pathogenic, what disease(s) is it associated with? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | GTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCT... | GTGGAGGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCT... | pathogenic | 36,653 |
Is the variant located on chromosome 2 at position 47801094, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, specify the disease(s) linked. | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | GGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTT... | GGTGGTGATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTT... | pathogenic | 36,657 |
Considering the genetic mutation at chromosome 2, position 47801100, impacting MSH6 (mutS homolog 6): is it clinically benign or pathogenic? Name the associated disease(s) if pathogenic. | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | GATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGA... | GATGACAGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGA... | pathogenic | 36,660 |
Variant in gene MSH6 (mutS homolog 6), located at chromosome 2 position 47801106: benign or pathogenic? What disease(s) does it cause if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | AGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGC... | AGTAGTCGCCCTACTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGC... | pathogenic | 36,663 |
Evaluate the clinical significance of the mutation at chromosome 2, position 47801119 in gene MSH6 (mutS homolog 6): benign or pathogenic? What disease(s) does a pathogenic variant suggest? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTAT... | CTGTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTAT... | pathogenic | 36,667 |
Clinical significance of chromosome 2, position 47801121, gene MSH6 (mutS homolog 6): benign or pathogenic? Name the disease(s) if pathogenic. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTC... | GTTTGGTATCATGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTC... | pathogenic | 36,669 |
Chromosome 2, position 47801132, gene MSH6 (mutS homolog 6): Is this mutation clinically benign or pathogenic? If pathogenic, identify the related disease(s). | pathogenic; ['Carcinoma_of_colon', 'Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGG... | TGAAACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGG... | pathogenic | 36,675 |
Clinical classification of chromosome 2, position 47801135, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s) if pathogenic? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | AACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGC... | AACTTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGC... | pathogenic | 36,677 |
Gene MSH6 (mutS homolog 6) variant at chromosome position 47801138 on chromosome 2: benign or pathogenic? If pathogenic, what disease(s) is it associated with? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGA... | TTTAGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGA... | pathogenic | 36,680 |
Regarding the variant at chromosome 2 and position 47801141, affecting gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the associated illness(es)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGG... | AGAATGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGG... | pathogenic | 36,682 |
Benign or pathogenic: chromosome 2, position 47801145, gene MSH6 (mutS homolog 6) variant? Disease(s) if pathogenic? | pathogenic; ['Carcinoma_of_colon', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGGGCTA... | TGGCTTAAGGAGGAAAAGAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGGGCTA... | pathogenic | 36,685 |
Chromosome 2, position 47801162, gene MSH6 (mutS homolog 6): benign or pathogenic variant? If pathogenic, what are the linked illness(es)? | benign | GAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGGGCTATAAAGTAGCACGAGTGG... | GAGAAGAGATGAGCACAGGAGGAGGCCTGATCACCCCGATTTTGATGCATCTACACTCTATGTGCCTGAGGATTTCCTCAATTCTTGTACTCCTGGGATGAGGAAGTGGTGGCAGATTAAGTCTCAGAACTTTGATCTTGTCATCTGTTACAAGGTGGGGAAATTTTATGAGCTGTACCACATGGATGCTCTTATTGGAGTCAGTGAACTGGGGCTGGTATTCATGAAAGGCAACTGGGCCCATTCTGGCTTTCCTGAAATTGCATTTGGCCGTTATTCAGATTCCCTGGTGCAGAAGGGCTATAAAGTAGCACGAGTGG... | benign | 36,697 |
Does the genetic variant at chromosome 2, position 47803404, impacting gene MSH6 (mutS homolog 6), appear benign or pathogenic? If pathogenic, name the associated disease(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | CTTCAGTTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTT... | CTTCAGTTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTT... | pathogenic | 36,711 |
Variant at chromosome position 47803405, chromosome 2, gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what condition(s) does it relate to? | benign | TTCAGTTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTC... | TTCAGTTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTC... | benign | 36,712 |
Determine whether the variant at chromosome 2, position 47803410, in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, identify the relevant disease(s). | benign | TTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCT... | TTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCT... | benign | 36,715 |
Is the variant located on chromosome 2 at position 47803410, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, specify the disease(s) linked. | benign | TTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCT... | TTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCT... | benign | 36,716 |
Located at chromosome 2 position 47803417, the variant affecting gene MSH6 (mutS homolog 6)—benign or pathogenic? If pathogenic, which disease(s) does it relate to? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | TTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAA... | TTTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAA... | pathogenic | 36,718 |
Considering the variant on chromosome 2, location 47803418, involving gene MSH6 (mutS homolog 6), would you classify it as benign or pathogenic? What disease(s), if any, does a pathogenic variant indicate? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | TTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAAT... | TTTTTTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAAT... | pathogenic | 36,720 |
Evaluate this variant at chromosome 2, position 47803422, gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the disease connection(s)? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | TTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAA... | TTTTTTTTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAA... | pathogenic | 36,723 |
Located at chromosome 2 position 47803428, the variant affecting gene MSH6 (mutS homolog 6)—benign or pathogenic? If pathogenic, which disease(s) does it relate to? | pathogenic; ['Lynch_syndrome'] | TTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAG... | TTTTTTTGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAG... | pathogenic | 36,725 |
Variant in gene MSH6 (mutS homolog 6), located at chromosome 2 position 47803434: benign or pathogenic? What disease(s) does it cause if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | TGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTT... | TGAGACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTT... | pathogenic | 36,729 |
Benign or pathogenic: chromosome 2, position 47803437, gene MSH6 (mutS homolog 6) variant? Disease(s) if pathogenic? | pathogenic; ['Lynch_syndrome_5'] | GACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTT... | GACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTT... | pathogenic | 36,732 |
Does the genetic variant at chromosome 2, position 47803437, impacting gene MSH6 (mutS homolog 6), appear benign or pathogenic? If pathogenic, name the associated disease(s). | pathogenic; ['Gastric_cancer', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms'] | GACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTT... | GACATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTT... | pathogenic | 36,733 |
Chromosome 2, position 47803440, gene MSH6 (mutS homolog 6): Is this mutation clinically benign or pathogenic? If pathogenic, identify the related disease(s). | pathogenic; ['Endometrial_carcinoma', 'Lynch_syndrome'] | ATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTT... | ATGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTT... | pathogenic | 36,734 |
Is the genetic variant on chromosome 2, position 47803441, gene MSH6 (mutS homolog 6), benign or pathogenic? If pathogenic, what disease(s) is indicated? | pathogenic; ['Lynch_syndrome'] | TGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTA... | TGGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTA... | pathogenic | 36,735 |
Is the genetic change at chromosome 2, position 47803442, within gene MSH6 (mutS homolog 6) benign or pathogenic? Name the disease(s) if pathogenic. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | GGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAG... | GGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAG... | pathogenic | 36,736 |
Regarding the variant found on chromosome 2 at position 47803442 in gene MSH6 (mutS homolog 6): is it benign or pathogenic? If pathogenic, identify the disease(s). | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAG... | GGTCTTGCTCTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAG... | pathogenic | 36,737 |
Gene mutation in MSH6 (mutS homolog 6) at chromosome 2, position 47803451—is it benign or pathogenic? If pathogenic, specify the disease(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCT... | CTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCT... | pathogenic | 36,743 |
Clinical classification of chromosome 2, position 47803451, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCT... | CTGTTGCCCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCT... | pathogenic | 36,746 |
Chromosome 2, position 47803458, gene MSH6 (mutS homolog 6): benign or pathogenic variant? If pathogenic, what are the linked illness(es)? | pathogenic; ['Endometrial_carcinoma', 'Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTG... | CCAGGCTAGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTG... | pathogenic | 36,748 |
Benign or pathogenic: chromosome 2, position 47803465, gene MSH6 (mutS homolog 6) variant? Disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | AGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCA... | AGAATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCA... | pathogenic | 36,752 |
A genetic variant on chromosome 2, position 47803467, affects the gene MSH6 (mutS homolog 6). Is this variant benign or pathogenic? If pathogenic, what disease(s) does it cause? | pathogenic; ['Lynch_syndrome'] | AATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGG... | AATATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGG... | pathogenic | 36,753 |
The mutation impacting MSH6 (mutS homolog 6) on chromosome 2 at position 47803469: benign or pathogenic? Name the associated disease(s) if pathogenic. | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGAC... | TATGGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGAC... | pathogenic | 36,754 |
Considering the genetic mutation at chromosome 2, position 47803472, impacting MSH6 (mutS homolog 6): is it clinically benign or pathogenic? Name the associated disease(s) if pathogenic. | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | GGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGA... | GGTGACACAACCATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGA... | pathogenic | 36,755 |
Does the genetic variant at chromosome 2, position 47803483, impacting gene MSH6 (mutS homolog 6), appear benign or pathogenic? If pathogenic, name the associated disease(s). | pathogenic; ['Gastric_cancer', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5'] | CATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTC... | CATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTC... | pathogenic | 36,761 |
Regarding the variant found on chromosome 2 at position 47803484 in gene MSH6 (mutS homolog 6): is it benign or pathogenic? If pathogenic, identify the disease(s). | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | ATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCA... | ATGGCTACTGCAGCCTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCA... | pathogenic | 36,762 |
Variant in gene MSH6 (mutS homolog 6), located at chromosome 2 position 47803498: benign or pathogenic? What disease(s) does it cause if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGC... | CTCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGC... | pathogenic | 36,770 |
Clinical classification of chromosome 2, position 47803499, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCT... | TCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCT... | pathogenic | 36,772 |
Variant at chromosome 2, position 47803499, gene MSH6 (mutS homolog 6): clinically benign or pathogenic? If pathogenic, specify the disease(s) involved. | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colon_cancer', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | TCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCT... | TCGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCT... | pathogenic | 36,773 |
Benign or pathogenic: chromosome 2, position 47803500, gene MSH6 (mutS homolog 6) variant? Disease(s) if pathogenic? | pathogenic; ['Breast_and/or_ovarian_cancer', 'Endometrial_carcinoma', 'Gastric_cancer', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Inherited_MMR_deficiency_(Lynch_syndrome)', 'Lynch-like_syndrome', 'Lynch_syndrome', 'Lynch_syndrome_5', 'MSH6-related_disorder', 'Mismatch_... | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | pathogenic | 36,774 |
A genetic alteration at chromosome 2, position 47803500, in gene MSH6 (mutS homolog 6)—benign or pathogenic? If pathogenic, which disease(s) is involved? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | pathogenic | 36,775 |
Is the genetic change at chromosome 2, position 47803500, within gene MSH6 (mutS homolog 6) benign or pathogenic? Name the disease(s) if pathogenic. | pathogenic; ['Carcinoma_of_colon', 'Endometrial_carcinoma', 'Gastric_cancer', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch-like_syndrome', 'Lynch_syndrome', 'Lynch_syndrome_5', 'MSH6-related_disorder', 'Mismatch_repair_cancer_syndrome_3'] | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | pathogenic | 36,776 |
Clinical impact (benign or pathogenic) of the variant at chromosome 2, location 47803500, gene MSH6 (mutS homolog 6): what disease(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | CGACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTA... | pathogenic | 36,777 |
Considering the genetic mutation at chromosome 2, position 47803501, impacting MSH6 (mutS homolog 6): is it clinically benign or pathogenic? Name the associated disease(s) if pathogenic. | pathogenic; ['Hereditary_cancer-predisposing_syndrome'] | GACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAG... | GACCTCCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAG... | pathogenic | 36,778 |
Gene MSH6 (mutS homolog 6) variant at chromosome 2, position 47803506—is it benign or pathogenic? If pathogenic, what are the associated condition(s)? | pathogenic; ['Lynch_syndrome'] | CCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTT... | CCCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTT... | pathogenic | 36,785 |
Evaluate if the mutation on chromosome 2 at position 47803507 in MSH6 (mutS homolog 6) is benign or pathogenic. Disease name(s) if pathogenic? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | CCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTA... | CCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTA... | pathogenic | 36,786 |
Variant chromosome 2, position 47803507, gene MSH6 (mutS homolog 6): benign or pathogenic? Disease(s)? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch-like_syndrome', 'Lynch_syndrome'] | CCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTA... | CCAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTA... | pathogenic | 36,787 |
Considering the variant on chromosome 2, location 47803508, involving gene MSH6 (mutS homolog 6), would you classify it as benign or pathogenic? What disease(s), if any, does a pathogenic variant indicate? | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome'] | CAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTAC... | CAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTAC... | pathogenic | 36,789 |
Does the chromosome 2 mutation at position 47803508 within gene MSH6 (mutS homolog 6) classify as benign or pathogenic? If pathogenic, indicate the related illness(es). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTAC... | CAGGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTAC... | pathogenic | 36,792 |
Evaluate this variant at chromosome 2, position 47803510, gene MSH6 (mutS homolog 6): benign or pathogenic? If pathogenic, what are the disease connection(s)? | pathogenic; ['Carcinoma_of_colon', 'Hereditary_cancer-predisposing_syndrome', 'Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome', 'Lynch_syndrome_5', 'Mismatch_repair_cancer_syndrome_3'] | GGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAG... | GGCTTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAG... | pathogenic | 36,793 |
Variant at chromosome 2, position 47803513, gene MSH6 (mutS homolog 6): clinically benign or pathogenic? If pathogenic, specify the disease(s) involved. | pathogenic; ['Lynch_syndrome_5'] | TTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTA... | TTAAGTGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTA... | pathogenic | 36,797 |
Determine if the mutation at chromosome 2, position 47803518 in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, what disease(s) is associated? | pathogenic; ['Lynch_syndrome'] | TGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCAC... | TGATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCAC... | pathogenic | 36,799 |
Classify the chromosome 2 variant at position 47803520 affecting gene MSH6 (mutS homolog 6) as benign or pathogenic. If pathogenic, which disease(s) is associated? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | ATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCG... | ATCTTTCCACCTCAGCCTCCCAAGTAGCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCG... | pathogenic | 36,800 |
Determine whether the variant at chromosome 2, position 47803546, in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, identify the relevant disease(s). | pathogenic; ['Hereditary_cancer-predisposing_syndrome', 'Lynch_syndrome_5'] | GCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCGGCGTGCCCTGCTTTATTTTTTTGGTG... | GCTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCGGCGTGCCCTGCTTTATTTTTTTGGTG... | pathogenic | 36,809 |
Determine if the mutation at chromosome 2, position 47803547 in gene MSH6 (mutS homolog 6) is benign or pathogenic. If pathogenic, what disease(s) is associated? | pathogenic; ['Hereditary_nonpolyposis_colorectal_neoplasms', 'Lynch_syndrome_5'] | CTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCGGCGTGCCCTGCTTTATTTTTTTGGTGG... | CTGAGATTACAGATATGCACCACCATGCATGGCTAATATTTAAATGTTTGTAGAGAGATGGGGTCTCACTGTGTTGCCAGGACTGGTCTTGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCGGCTTCCCAAAGTGCTGAGGTTACAGGCATGACCCATTGCGCCTGGCCCTTTCTTCAGTCTTTAATAATCGAACAAAAGGTTTTTGTTTTTAGACAGTGTCTTGCTCTGTTACCCAGGACAGACCTCTCGTGTCAGCCTCTTAGGTAGCTAGGATTTACAGGTAAGCACCGGCGTGCCCTGCTTTATTTTTTTGGTGG... | pathogenic | 36,813 |
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