accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P21673 | SAT1_HUMAN | Spermidine/spermine N(1)-acetyltransferase 1 | Homo | <M><A><K><F><V><I><R><P><A><T><A><A><D><C><S><D><I><L><R><L><I><K><E><L><A><K><Y><E><Y><M><E><E><Q><V><I><L><T><E><K><D><L><L><E><D><G><F><G><E><H><P><F><Y><H><C><L><V><A><E><V><P><K><E><H><W><T><P><E><G><H><S><I><V><G><F><A><M><Y><Y><F><T><Y><D><P><W><I><G><K><L><L><Y><L><E><D><F><F><V><M><S><D><Y><R><G><F><G><I><G><S... | Enzyme which catalyzes the acetylation of polyamines . Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine . This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines . Also involved in the regulation of polyamine transport out of cells . Als... | P21673 |
P17735 | ATTY_HUMAN | L-tyrosine:2-oxoglutarate aminotransferase | Homo | <M><D><P><Y><M><I><Q><M><S><S><K><G><N><L><P><S><I><L><D><V><H><V><N><V><G><G><R><S><S><V><P><G><K><M><K><G><R><K><A><R><W><S><V><R><P><S><D><M><A><K><K><T><F><N><P><I><R><A><I><V><D><N><M><K><V><K><P><N><P><N><K><T><M><I><S><L><S><I><G><D><P><T><V><F><G><N><L><P><T><D><P><E><V><T><Q><A><M><K><D><A><L><D><S><G><K><Y><N... | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.<BOP> | P17735 |
Q96FT7 | ASIC4_HUMAN | Amiloride-sensitive cation channel 4, pituitary | Homo | <M><P><I><E><I><V><C><K><I><K><F><A><E><E><D><A><K><P><K><E><K><E><A><G><D><E><Q><S><L><L><G><A><V><A><P><G><A><A><P><R><D><L><A><T><F><A><S><T><S><T><L><H><G><L><G><R><A><C><G><P><G><P><H><G><L><R><R><T><L><W><A><L><A><L><L><T><S><L><A><A><F><L><Y><Q><A><A><G><L><A><R><G><Y><L><T><R><P><H><L><V><A><M><D><P><A><A><P><A... | Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.<BOP> | Q96FT7 |
Q9Y6J8 | STYL1_HUMAN | Map kinase phosphatase-like protein MK-STYX | Homo | <M><P><G><L><L><L><C><E><P><T><E><L><Y><N><I><L><N><Q><A><T><K><L><S><R><L><T><D><P><N><Y><L><C><L><L><D><V><R><S><K><W><E><Y><D><E><S><H><V><I><T><A><L><R><V><K><K><K><N><N><E><Y><L><L><P><E><S><V><D><L><E><C><V><K><Y><C><V><V><Y><D><N><N><S><S><T><L><E><I><L><L><K><D><D><D><D><D><S><D><S><D><G><D><G><K><D><L><V><P><Q... | Catalytically inactive phosphatase . By binding to G3BP1, inhibits the formation of G3BP1-induced stress granules . Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149' . Inhibits PTPMT1 phosphatase activity . By inhibiting PTPMT1, positively regulates intrinsic apoptosis . May play a role in the form... | Q9Y6J8 |
Q96FL9 | GLT14_HUMAN | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 | Homo | <M><R><R><L><T><R><R><L><V><L><P><V><F><G><V><L><W><I><T><V><L><L><F><F><W><V><T><K><R><K><L><E><V><P><T><G><P><E><V><Q><T><P><K><P><S><D><A><D><W><D><D><L><W><D><Q><F><D><E><R><R><Y><L><N><A><K><K><W><R><V><G><D><D><P><Y><K><L><Y><A><F><N><Q><R><E><S><E><R><I><S><S><N><R><A><I><P><D><T><R><H><L><R><C><T><L><L><V><Y><C... | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation... | Q96FL9 |
Q9Y689 | ARL5A_HUMAN | ADP-ribosylation factor-like protein 5A | Homo | <M><G><I><L><F><T><R><I><W><R><L><F><N><H><Q><E><H><K><V><I><I><V><G><L><D><N><A><G><K><T><T><I><L><Y><Q><F><S><M><N><E><V><V><H><T><S><P><T><I><G><S><N><V><E><E><I><V><I><N><N><T><R><F><L><M><W><D><I><G><G><Q><E><S><L><R><S><S><W><N><T><Y><Y><T><N><T><E><F><V><I><V><V><V><D><S><T><D><R><E><R><I><S><V><T><R><E><E><L><Y... | Lacks ADP-ribosylation enhancing activity.<BOP> | Q9Y689 |
P10515 | ODP2_HUMAN | Pyruvate dehydrogenase complex component E2 | Homo | <M><W><R><V><C><A><R><R><A><Q><N><V><A><P><W><A><G><L><E><A><R><W><T><A><L><Q><E><V><P><G><T><P><R><V><T><S><R><S><G><P><A><P><A><R><R><N><S><V><T><T><G><Y><G><G><V><R><A><L><C><G><W><T><P><S><S><G><A><T><P><R><N><R><L><L><L><Q><L><L><G><S><P><G><R><R><Y><Y><S><L><P><P><H><Q><K><V><P><L><P><S><L><S><P><T><M><Q><A><G><T... | The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.<BOP> | P10515 |
Q96GV9 | MACIR_HUMAN | Macrophage immunometabolism regulator | Homo | <M><E><V><D><I><N><G><E><S><R><S><T><L><T><T><L><P><F><P><G><A><E><A><N><S><P><G><K><A><E><A><E><K><P><R><C><S><S><T><P><C><S><P><M><R><R><T><V><S><G><Y><Q><I><L><H><M><D><S><N><Y><L><V><G><F><T><T><G><E><E><L><L><K><L><A><Q><K><C><T><G><G><E><E><S><K><A><E><A><M><P><S><L><R><S><K><Q><L><D><A><G><L><A><R><S><S><R><L><Y... | Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages . The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis . May also play a role in trafficking of proteins via its interaction with UNC119 an... | Q96GV9 |
A0A0A0MTA7 | TJB21_HUMAN | T cell receptor beta joining 2-1 | Homo | <S><Y><N><E><Q><F><F><G><P><G><T><R><L><T><V><L> | J region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0A0MTA7 |
Q9Y4A9 | O10H1_HUMAN | Olfactory receptor OR19-27 | Homo | <M><Q><R><A><N><H><S><T><V><T><Q><F><I><L><V><G><F><S><V><F><P><H><L><Q><L><M><L><F><L><L><F><L><L><M><Y><L><F><T><L><L><G><N><L><L><I><M><A><T><V><W><S><E><R><S><L><H><T><P><M><Y><L><F><L><C><A><L><S><V><S><E><I><L><Y><T><V><A><I><I><P><R><M><L><A><D><L><L><S><T><Q><R><S><I><A><F><L><A><C><A><S><Q><M><F><F><S><F><S><F... | Odorant receptor.<BOP> | Q9Y4A9 |
Q8NBW4 | S38A9_HUMAN | Up-regulated in lung cancer 11 | Homo | <M><A><N><M><N><S><D><S><R><H><L><G><T><S><E><V><D><H><E><R><D><P><G><P><M><N><I><Q><F><E><P><S><D><L><R><S><K><R><P><F><C><I><E><P><T><N><I><V><N><V><N><H><V><I><Q><R><V><S><D><H><A><S><A><M><N><K><R><I><H><Y><Y><S><R><L><T><T><P><A><D><K><A><L><I><A><P><D><H><V><V><P><A><P><E><E><C><Y><V><Y><S><P><L><G><S><A><Y><K><L... | Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth f... | Q8NBW4 |
A0A494C1R9 | TSPY9_HUMAN | Testis-specific Y-encoded protein 9 | Homo | <M><R><P><E><G><S><L><T><Y><R><V><P><E><R><L><R><Q><G><F><C><G><V><G><R><A><A><Q><A><L><V><C><A><S><A><K><E><G><T><A><F><R><M><E><A><V><Q><E><G><A><A><G><V><E><S><E><Q><A><A><L><G><E><E><A><V><L><L><L><D><D><I><M><A><E><V><E><V><V><A><E><V><E><V><V><A><E><E><E><G><L><V><E><R><R><E><E><A><Q><R><A><Q><Q><A><V><P><G><P><G... | May be involved in sperm differentiation and proliferation.<BOP> | A0A494C1R9 |
Q9H295 | DCSTP_HUMAN | Transmembrane 7 superfamily member 4 | Homo | <M><G><I><W><T><S><G><T><D><I><F><L><S><L><W><E><I><Y><V><S><P><R><S><P><G><W><M><D><F><I><Q><H><L><G><V><C><C><L><V><A><L><I><S><V><G><L><L><S><V><A><A><C><W><F><L><P><S><I><I><A><A><A><A><S><W><I><I><T><C><V><L><L><C><C><S><K><H><A><R><C><F><I><L><L><V><F><L><S><C><G><L><R><E><G><R><N><A><L><I><A><A><G><T><G><I><V><I... | Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast ... | Q9H295 |
Q9BY08 | EBPL_HUMAN | Emopamil-binding-related protein | Homo | <M><G><A><E><W><E><L><G><A><E><A><G><G><S><L><L><L><C><A><A><L><L><A><A><G><C><A><L><G><L><R><L><G><R><G><Q><G><A><A><D><R><G><A><L><I><W><L><C><Y><D><A><L><V><H><F><A><L><E><G><P><F><V><Y><L><S><L><V><G><N><V><A><N><S><D><G><L><I><A><S><L><W><K><E><Y><G><K><A><D><A><R><W><V><Y><F><D><P><T><I><V><S><V><E><I><L><T><V><A... | Does not possess sterol isomerase activity and does not bind sigma ligands.<BOP> | Q9BY08 |
Q13769 | THOC5_HUMAN | hTREX90 | Homo | <M><S><S><E><S><S><K><K><R><K><P><K><V><I><R><S><D><G><A><P><A><E><G><K><R><N><R><S><D><T><E><Q><E><G><K><Y><Y><S><E><E><A><E><V><D><L><R><D><P><G><R><D><Y><E><L><Y><K><Y><T><C><Q><E><L><Q><R><L><M><A><E><I><Q><D><L><K><S><R><G><G><K><D><V><A><I><E><I><E><E><R><R><I><Q><S><C><V><H><F><M><T><L><K><K><L><N><R><L><A><H><I... | Regulates the expression of myeloid transcription factors CEBPA, CEBPB and GAB2 by enhancing the levels of phosphatidylinositol 3,4,5-trisphosphate. May be involved in the differentiation of granulocytes and adipocytes. Essential for hematopoietic primitive cell survival and plays an integral role in monocytic developm... | Q13769 |
P50221 | MEOX1_HUMAN | Mesenchyme homeobox 1 | Homo | <M><D><P><A><A><S><S><C><M><R><S><L><Q><P><P><A><P><V><W><G><C><L><R><N><P><H><S><E><G><N><G><A><S><G><L><P><H><Y><P><P><T><P><F><S><F><H><Q><K><P><D><F><L><A><T><A><T><A><A><Y><P><D><F><S><A><S><C><L><A><A><T><P><H><S><L><P><Q><E><E><H><I><F><T><E><Q><H><P><A><F><P><Q><S><P><N><W><H><F><P><V><S><D><A><R><R><R><P><N><S... | Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints . Binds specifically to the promoter of target genes and regulates their expression. Activates e... | P50221 |
Q92959 | SO2A1_HUMAN | Solute carrier family 21 member 2 | Homo | <M><G><L><L><P><K><L><G><A><S><Q><G><S><D><T><S><T><S><R><A><G><R><C><A><R><S><V><F><G><N><I><K><V><F><V><L><C><Q><G><L><L><Q><L><C><Q><L><L><Y><S><A><Y><F><K><S><S><L><T><T><I><E><K><R><F><G><L><S><S><S><S><S><G><L><I><S><S><L><N><E><I><S><N><A><I><L><I><I><F><V><S><Y><F><G><S><R><V><H><R><P><R><L><I><G><I><G><G><L><F... | Transports PGD2, as well as PGE1, PGE2 and PGF2A. Mediates the clearance of prostaglandins from the circulation through uptake across cell membrane which allows cytoplasmic oxidation and prostaglandin signal termination . May mediate the release of newly synthesized prostaglandins from cells and the transepithelial tra... | Q92959 |
P0DP57 | SLUR2_HUMAN | Secreted Ly-6/uPAR-related protein 2 | Homo | <M><Q><L><G><T><G><L><L><L><A><A><V><L><S><L><Q><L><A><A><A><E><A><I><W><C><H><Q><C><T><G><F><G><G><C><S><H><G><S><R><C><L><R><D><S><T><H><C><V><T><T><A><T><R><V><L><S><N><T><E><D><L><P><L><V><T><K><M><C><H><I><G><C><P><D><I><P><S><L><G><L><G><P><Y><V><S><I><A><C><C><Q><T><S><L><C><N><H><D> | Binds and may modulate the functional properties of nicotinic and muscarinic acetylcholine receptors. May regulate keratinocytes proliferation, differentiation and apoptosis. In vitro moderately inhibits ACh-evoked currents of alpha-3:beta-2-containing nAChRs and strongly these of alpha-4:beta-2-containing nAChRs, modu... | P0DP57 |
Q96A73 | P33MX_HUMAN | Flavin monooxygenase motif-containing protein of 33 kDa | Homo | <M><A><S><R><Q><P><E><V><P><A><L><E><A><S><A><P><L><G><K><M><S><L><P><I><G><I><Y><R><R><A><V><S><Y><D><D><T><L><E><D><P><A><P><M><T><P><P><P><S><D><M><G><S><V><P><W><K><P><V><I><P><E><R><K><Y><Q><H><L><A><K><V><E><E><G><E><A><S><L><P><S><P><A><M><T><L><S><S><A><I><D><S><V><D><K><V><P><V><V><K><A><K><A><T><H><V><I><M><N... | Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.<BOP> | Q96A73 |
P12829 | MYL4_HUMAN | Myosin light chain alkali GT-1 isoform | Homo | <M><A><P><K><K><P><E><P><K><K><E><A><A><K><P><A><P><A><P><A><P><A><P><A><P><A><P><A><P><A><P><E><A><P><K><E><P><A><F><D><P><K><S><V><K><I><D><F><T><A><D><Q><I><E><E><F><K><E><A><F><S><L><F><D><R><T><P><T><G><E><M><K><I><T><Y><G><Q><C><G><D><V><L><R><A><L><G><Q><N><P><T><N><A><E><V><L><R><V><L><G><K><P><K><P><E><E><M><N... | Regulatory light chain of myosin. Does not bind calcium.<BOP> | P12829 |
A0A286YEY9 | SCGR1_HUMAN | Keratin-associated protein 28-1 | Homo | <M><G><C><C><G><C><G><G><C><G><G><C><G><G><C><G><G><G><C><G><G><G><C><G><R><C><T><T><C><R><C><Y><R><V><G><C><C><S><S><C><C><P><C><C><R><G><C><C><G><G><C><C><S><T><P><V><I><C><C><C><R><R><T><C><S><S><C><G><Y><S><C><G><K><G><C><C><Q><Q><K><C><C><C><Q><K><Q><C><C><C> | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | A0A286YEY9 |
Q9BSA4 | TTYH2_HUMAN | Protein tweety homolog 2 | Homo | <M><Q><A><A><R><V><D><Y><I><A><P><W><W><V><V><W><L><H><S><V><P><H><V><G><L><R><L><Q><P><V><N><S><T><F><S><P><G><D><E><S><Y><Q><E><S><L><L><F><L><G><L><V><A><A><V><C><L><G><L><N><L><I><F><L><V><A><Y><L><V><C><A><C><H><C><R><R><D><D><A><V><Q><T><K><Q><H><H><S><C><C><I><T><W><T><A><V><V><A><G><L><I><C><C><A><A><V><G><V><G... | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.<BOP> | Q9BSA4 |
Q9H7P6 | MB12B_HUMAN | Protein FAM125B | Homo | <M><R><S><C><F><C><V><R><R><S><R><D><P><P><P><P><Q><P><P><P><P><P><P><Q><R><G><T><D><Q><S><T><M><P><E><V><K><D><L><S><E><A><L><P><E><T><S><M><D><P><I><T><G><V><G><V><V><A><S><R><N><R><A><P><T><G><Y><D><V><V><A><Q><T><A><D><G><V><D><A><D><L><W><K><D><G><L><F><K><S><K><V><T><R><Y><L><C><F><T><R><S><F><S><K><E><N><S><H><L... | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.<BOP> | Q9H7P6 |
Q8WVV5 | BT2A2_HUMAN | Butyrophilin subfamily 2 member A2 | Homo | <M><E><P><A><A><A><L><H><F><S><L><P><A><S><L><L><L><L><L><L><L><L><L><L><S><L><C><A><L><V><S><A><Q><F><T><V><V><G><P><A><N><P><I><L><A><M><V><G><E><N><T><T><L><R><C><H><L><S><P><E><K><N><A><E><D><M><E><V><R><W><F><R><S><Q><F><S><P><A><V><F><V><Y><K><G><G><R><E><R><T><E><E><Q><M><E><E><Y><R><G><R><I><T><F><V><S><K><D><I... | Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.<BOP> | Q8WVV5 |
Q8NGS7 | O13C8_HUMAN | Olfactory receptor 13C8 | Homo | <M><E><R><T><N><D><S><T><S><T><E><F><F><L><V><G><L><S><A><H><P><K><L><Q><T><V><F><F><V><L><I><L><W><M><Y><L><M><I><L><L><G><N><G><V><L><I><S><V><I><I><F><D><S><H><L><H><T><P><M><Y><F><F><L><C><N><L><S><F><L><D><V><C><Y><T><S><S><S><V><P><L><I><L><A><S><F><L><A><V><K><K><K><V><S><F><S><G><C><M><V><Q><M><F><I><S><F><A><M... | Odorant receptor.<BOP> | Q8NGS7 |
Q9NP31 | SH22A_HUMAN | VEGF receptor-associated protein | Homo | <M><E><F><P><L><A><Q><I><C><P><Q><G><S><H><E><A><P><I><P><T><F><S><T><F><Q><I><T><D><M><T><R><R><S><C><Q><N><L><G><Y><T><A><A><S><P><Q><A><P><E><A><A><S><N><T><G><N><A><E><R><A><E><E><V><P><G><E><G><S><L><F><L><Q><A><E><T><R><A><W><F><Q><K><T><Q><A><H><W><L><L><Q><H><G><A><A><P><A><W><F><H><G><F><I><T><R><R><E><A><E><R... | Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with... | Q9NP31 |
Q8TDT2 | GP152_HUMAN | G-protein coupled receptor PGR5 | Homo | <M><D><T><T><M><E><A><D><L><G><A><T><G><H><R><P><R><T><E><L><D><D><E><D><S><Y><P><Q><G><G><W><D><T><V><F><L><V><A><L><L><L><L><G><L><P><A><N><G><L><M><A><W><L><A><G><S><Q><A><R><H><G><A><G><T><R><L><A><L><L><L><L><S><L><A><L><S><D><F><L><F><L><A><A><A><A><F><Q><I><L><E><I><R><H><G><G><H><W><P><L><G><T><A><A><C><R><F><Y... | Orphan receptor.<BOP> | Q8TDT2 |
P17677 | NEUM_HUMAN | pp46 | Homo | <M><L><C><C><M><R><R><T><K><Q><V><E><K><N><D><D><D><Q><K><I><E><Q><D><G><I><K><P><E><D><K><A><H><K><A><A><T><K><I><Q><A><S><F><R><G><H><I><T><R><K><K><L><K><G><E><K><K><D><D><V><Q><A><A><E><A><E><A><N><K><K><D><E><A><P><V><A><D><G><V><E><K><K><G><E><G><T><T><T><A><E><A><A><P><A><T><G><S><K><P><D><E><P><G><K><A><G><E><T... | This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.<BOP> | P17677 |
Q8WW43 | APH1B_HUMAN | Presenilin-stabilization factor-like | Homo | <M><T><A><A><V><F><F><G><C><A><F><I><A><F><G><P><A><L><A><L><Y><V><F><T><I><A><T><E><P><L><R><I><I><F><L><I><A><G><A><F><F><W><L><V><S><L><L><I><S><S><L><V><W><F><M><A><R><V><I><I><D><N><K><D><G><P><T><Q><K><Y><L><L><I><F><G><A><F><V><S><V><Y><I><Q><E><M><F><R><F><A><Y><Y><K><L><L><K><K><A><S><E><G><L><K><S><I><N><P><G... | Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable com... | Q8WW43 |
Q496M5 | PLK5_HUMAN | Polo-like kinase 5 | Homo | <M><Y><T><V><L><T><G><T><P><P><F><M><A><S><P><L><S><E><M><Y><Q><N><I><R><E><G><H><Y><P><E><P><A><H><L><S><A><N><A><R><R><L><I><V><H><L><L><A><P><N><P><A><E><R><P><S><L><D><H><L><L><Q><D><D><F><F><T><Q><G><F><T><P><D><R><L><P><A><H><S><C><H><S><P><P><I><F><A><I><P><P><P><L><G><R><I><F><R><K><V><G><Q><R><L><L><T><Q><C><R... | Inactive serine/threonine-protein kinase that plays a role in cell cycle progression and neuronal differentiation.<BOP> | Q496M5 |
Q9H3M9 | ATX3L_HUMAN | Machado-Joseph disease protein 1-like | Homo | <M><D><F><I><F><H><E><K><Q><E><G><F><L><C><A><Q><H><C><L><N><N><L><L><Q><G><E><Y><F><S><P><V><E><L><A><S><I><A><H><Q><L><D><E><E><E><R><M><R><M><A><E><G><G><V><T><S><E><E><Y><L><A><F><L><Q><Q><P><S><E><N><M><D><D><T><G><F><F><S><I><Q><V><I><S><N><A><L><K><F><W><G><L><E><I><I><H><F><N><N><P><E><Y><Q><K><L><G><I><D><P><I... | Deubiquitinating enzyme that cleaves both 'Lys-48'-linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro).<BOP> | Q9H3M9 |
Q6ZNG1 | ZN600_HUMAN | Zinc finger protein 600 | Homo | <M><M><K><E><V><L><S><T><G><Q><G><N><T><E><V><I><H><T><G><T><L><Q><R><Y><Q><S><Y><H><I><G><D><F><C><F><Q><E><I><E><K><E><I><H><D><I><E><F><Q><C><Q><E><D><E><R><N><G><H><E><A><P><M><T><K><I><K><K><L><T><G><S><T><D><Q><H><D><H><R><H><A><G><N><K><P><I><K><D><Q><L><G><S><S><F><Y><S><H><L><P><E><L><H><I><I><Q><I><K><G><K><I... | May be involved in transcriptional regulation.<BOP> | Q6ZNG1 |
P82909 | KGD4_HUMAN | Alpha-ketoglutarate dehydrogenase component 4 | Homo | <M><M><G><S><K><M><A><S><A><S><R><V><V><Q><V><V><K><P><H><T><P><L><I><R><F><P><D><R><R><D><N><P><K><P><N><V><S><E><A><L><R><S><A><G><L><P><S><H><S><S><V><I><S><Q><H><S><K><G><S><K><S><P><D><L><L><M><Y><Q><G><P><P><D><T><A><E><I><I><K><T><L><P><Q><K><Y><R><R><K><L><V><S><Q><E><E><M><E><F><I><Q><R><G><G><P><E> | May be necessary to recruit DLD/E3 to the mitochondrial 2-oxoglutarate dehydrogenase complex (OGDC) core composed of OGDH/E1-DLST/E2, hence stabilizes the complex.<BOP> | P82909 |
A0A087WSY4 | HV432_HUMAN | Immunoglobulin heavy variable 4-30-2 | Homo | <M><K><H><L><W><F><F><L><L><L><V><A><A><P><R><W><V><L><S><Q><L><Q><L><Q><E><S><G><S><G><L><V><K><P><S><Q><T><L><S><L><T><C><A><V><S><G><G><S><I><S><S><G><G><Y><S><W><S><W><I><R><Q><P><P><G><K><G><L><E><W><I><G><Y><I><Y><H><S><G><S><T><Y><Y><N><P><S><L><K><S><R><V><T><I><S><V><D><R><S><K><N><Q><F><S><L><K><L><S><S><V><T... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A087WSY4 |
Q6ZNC4 | ZN704_HUMAN | Zinc finger protein 704 | Homo | <M><T><F><T><F><Q><S><E><D><L><K><R><D><C><G><K><K><M><S><H><Q><H><V><F><S><L><A><M><E><E><D><V><K><T><A><D><T><K><K><A><S><R><I><L><D><H><E><K><E><N><T><R><S><I><C><L><L><E><Q><K><R><K><V><V><S><S><N><I><D><V><P><P><A><R><K><S><S><E><E><L><D><M><D><K><V><T><A><A><M><V><L><T><S><L><S><T><S><P><L><V><R><S><P><P><V><R><P... | Transcription factor which binds to RE2 sequence elements in the MYOD1 enhancer.<BOP> | Q6ZNC4 |
P0C617 | O5AL1_HUMAN | Olfactory receptor OR11-184 | Homo | <M><C><A><L><K><G><F><L><E><E><N><F><Y><T><Y><S><V><A><K><G><N><H><S><T><V><Y><E><F><I><L><L><G><L><T><D><N><A><E><L><Q><V><T><L><F><G><I><F><L><V><V><Y><L><A><S><F><M><G><N><F><G><L><I><M><L><I><Q><I><S><P><Q><L><H><T><P><M><Y><F><F><L><S><H><L><A><F><V><D><F><S><F><T><S><S><V><A><P><N><T><L><V><N><F><L><C><E><V><K><S... | Odorant receptor.<BOP> | P0C617 |
P21953 | ODBB_HUMAN | Branched-chain alpha-keto acid dehydrogenase E1 component beta chain | Homo | <M><A><V><V><A><A><A><A><G><W><L><L><R><L><R><A><A><G><A><E><G><H><W><R><R><L><P><G><A><G><L><A><R><G><F><L><H><P><A><A><T><V><E><D><A><A><Q><R><R><Q><V><A><H><F><T><F><Q><P><D><P><E><P><R><E><Y><G><Q><T><Q><K><M><N><L><F><Q><S><V><T><S><A><L><D><N><S><L><A><K><D><P><T><A><V><I><F><G><E><D><V><A><F><G><G><V><F><R><C><T... | The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).<BOP> | P21953 |
Q8IUR6 | CRERF_HUMAN | Luman recruitment factor | Homo | <M><P><Q><P><S><V><S><G><M><D><P><P><F><G><D><A><F><R><S><H><T><F><S><E><Q><T><L><M><S><T><D><L><L><A><N><S><S><D><P><D><F><M><Y><E><L><D><R><E><M><N><Y><Q><Q><N><P><R><D><N><F><L><S><L><E><D><C><K><D><I><E><N><L><E><S><F><T><D><V><L><D><N><E><G><A><L><T><S><N><W><E><Q><W><D><T><Y><C><E><D><L><T><K><Y><T><K><L><T><S><C... | Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.<BOP> | Q8IUR6 |
P02745 | C1QA_HUMAN | Complement C1q subcomponent subunit A | Homo | <M><E><G><P><R><G><W><L><V><L><C><V><L><A><I><S><L><A><S><M><V><T><E><D><L><C><R><A><P><D><G><K><K><G><E><A><G><R><P><G><R><R><G><R><P><G><L><K><G><E><Q><G><E><P><G><A><P><G><I><R><T><G><I><Q><G><L><K><G><D><Q><G><E><P><G><P><S><G><N><P><G><K><V><G><Y><P><G><P><S><G><P><L><G><A><R><G><I><P><G><I><K><G><T><K><G><S><P><G... | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions o... | P02745 |
Q96K80 | ZC3HA_HUMAN | Zinc finger CCCH domain-containing protein 10 | Homo | <M><P><D><R><D><S><Y><A><N><G><T><G><S><S><G><G><G><P><G><G><G><G><S><E><E><A><S><G><A><G><V><G><S><G><G><A><S><S><D><A><I><C><R><D><F><L><R><N><V><C><K><R><G><K><R><C><R><Y><R><H><P><D><M><S><E><V><S><N><L><G><V><S><K><N><E><F><I><F><C><H><D><F><Q><N><K><E><C><S><R><P><N><C><R><F><I><H><G><S><K><E><D><E><D><G><Y><K><K... | Specific regulator of miRNA biogenesis. Binds, via the C3H1-type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA.<BOP> | Q96K80 |
O60637 | TSN3_HUMAN | Transmembrane 4 superfamily member 8 | Homo | <M><G><Q><C><G><I><T><S><S><K><T><V><L><V><F><L><N><L><I><F><W><G><A><A><G><I><L><C><Y><V><G><A><Y><V><F><I><T><Y><D><D><Y><D><H><F><F><E><D><V><Y><T><L><I><P><A><V><V><I><I><A><V><G><A><L><L><F><I><I><G><L><I><G><C><C><A><T><I><R><E><S><R><C><G><L><A><T><F><V><I><I><L><L><L><V><F><V><T><E><V><V><V><V><V><L><G><Y><V><Y... | Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.<BOP> | O60637 |
Q9Y2Q1 | ZN257_HUMAN | Bone marrow zinc finger 4 | Homo | <M><G><P><L><T><I><R><D><V><T><V><E><F><S><L><E><E><W><H><C><L><D><T><A><Q><Q><N><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><F><L><G><I><A><V><S><K><P><D><L><I><T><C><L><E><Q><G><K><E><P><C><N><M><K><R><H><E><M><V><A><K><P><P><V><M><C><S><H><I><A><E><D><L><C><P><E><R><D><I><K><Y><F><F><Q><K><V><I><L><R><R><Y><D><K><C><E... | May be involved in transcriptional regulation.<BOP> | Q9Y2Q1 |
Q8N8U3 | RTL3_HUMAN | Zinc finger CCHC domain-containing protein 5 | Homo | <M><V><E><D><L><A><A><S><Y><I><V><L><K><L><E><N><E><I><R><Q><A><Q><V><Q><W><L><M><E><E><N><A><A><L><Q><A><Q><I><P><E><L><Q><K><S><Q><A><A><K><E><Y><D><L><L><R><K><S><S><E><A><K><E><P><Q><K><L><P><E><H><M><N><P><P><A><A><W><E><A><Q><K><T><P><E><F><K><E><P><Q><K><P><P><E><P><Q><D><L><L><P><W><E><P><P><A><A><W><E><L><Q><E... | May function as a transcriptional regulator. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal.<BOP> | Q8N8U3 |
O15371 | EIF3D_HUMAN | eIF3 p66 | Homo | <M><A><K><F><M><T><P><V><I><Q><D><N><P><S><G><W><G><P><C><A><V><P><E><Q><F><R><D><M><P><Y><Q><P><F><S><K><G><D><R><L><G><K><V><A><D><W><T><G><A><T><Y><Q><D><K><R><Y><T><N><K><Y><S><S><Q><F><G><G><G><S><Q><Y><A><Y><F><H><E><E><D><E><S><S><F><Q><L><V><D><T><A><R><T><Q><K><T><A><Y><Q><R><N><R><M><R><F><A><Q><R><N><L><R><R... | (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 .<BOP> | O15371 |
Q86WR0 | CCD25_HUMAN | Coiled-coil domain-containing protein 25 | Homo | <M><V><F><Y><F><T><S><S><S><V><N><S><S><A><Y><T><I><Y><M><G><K><D><K><Y><E><N><E><D><L><I><K><H><G><W><P><E><D><I><W><F><H><V><D><K><L><S><S><A><H><V><Y><L><R><L><H><K><G><E><N><I><E><D><I><P><K><E><V><L><M><D><C><A><H><L><V><K><A><N><S><I><Q><G><C><K><M><N><N><V><N><V><V><Y><T><P><W><S><N><L><K><K><T><A><D><M><D><V><G... | Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility . NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation . Formation of NETs is also associated with cancer metastasis, NET-DNA actin... | Q86WR0 |
Q99439 | CNN2_HUMAN | Neutral calponin | Homo | <M><S><S><T><Q><F><N><K><G><P><S><Y><G><L><S><A><E><V><K><N><R><L><L><S><K><Y><D><P><Q><K><E><A><E><L><R><T><W><I><E><G><L><T><G><L><S><I><G><P><D><F><Q><K><G><L><K><D><G><T><I><L><C><T><L><M><N><K><L><Q><P><G><S><V><P><K><I><N><R><S><M><Q><N><W><H><Q><L><E><N><L><S><N><F><I><K><A><M><V><S><Y><G><M><N><P><V><D><L><F><E... | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.<BOP> | Q99439 |
Q9HCU5 | PREB_HUMAN | Mammalian guanine nucleotide exchange factor mSec12 | Homo | <M><G><R><R><R><A><P><E><L><Y><R><A><P><F><P><L><Y><A><L><Q><V><D><P><S><T><G><L><L><I><A><A><G><G><G><G><A><A><K><T><G><I><K><N><G><V><H><F><L><Q><L><E><L><I><N><G><R><L><S><A><S><L><L><H><S><H><D><T><E><T><R><A><T><M><N><L><A><L><A><G><D><I><L><A><A><G><Q><D><A><H><C><Q><L><L><R><F><Q><A><H><Q><Q><Q><G><N><K><A><E><K... | Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.<BOP> | Q9HCU5 |
P51809 | VAMP7_HUMAN | Tetanus-insensitive VAMP | Homo | <M><A><I><L><F><A><V><V><A><R><G><T><T><I><L><A><K><H><A><W><C><G><G><N><F><L><E><V><T><E><Q><I><L><A><K><I><P><S><E><N><N><K><L><T><Y><S><H><G><N><Y><L><F><H><Y><I><C><Q><D><R><I><V><Y><L><C><I><T><D><D><D><F><E><R><S><R><A><F><N><F><L><N><E><I><K><K><R><F><Q><T><T><Y><G><S><R><A><Q><T><A><L><P><Y><A><M><N><S><E><F><S... | Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in t... | P51809 |
Q6IQ21 | ZN770_HUMAN | Zinc finger protein 770 | Homo | <M><M><A><E><N><N><L><K><M><L><K><I><Q><Q><C><V><V><A><N><K><L><P><R><N><R><P><Y><V><C><N><I><C><F><K><H><F><E><T><P><S><K><L><A><R><H><Y><L><I><H><T><G><Q><K><P><F><E><C><D><V><C><H><K><T><F><R><Q><L><V><H><L><E><R><H><Q><L><T><H><S><L><P><F><K><C><S><I><C><Q><R><H><F><K><N><L><K><T><F><V><K><H><Q><Q><L><H><N><E><T><Y... | May be involved in transcriptional regulation.<BOP> | Q6IQ21 |
Q9P2W9 | STX18_HUMAN | Cell growth-inhibiting gene 9 protein | Homo | <M><A><V><D><I><T><L><L><F><R><A><S><V><K><T><V><K><T><R><N><K><A><L><G><V><A><V><G><G><G><V><D><G><S><R><D><E><L><F><R><R><S><P><R><P><K><G><D><F><S><S><R><A><R><E><V><I><S><H><I><G><K><L><R><D><F><L><L><E><H><R><K><D><Y><I><N><A><Y><S><H><T><M><S><E><Y><G><R><M><T><D><T><E><R><D><Q><I><D><Q><D><A><Q><I><F><M><R><T><C... | Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.<BOP> | Q9P2W9 |
Q7L1T6 | NB5R4_HUMAN | cb5/cb5R | Homo | <M><L><N><V><P><S><Q><S><F><P><A><P><R><S><Q><Q><R><V><A><S><G><G><R><S><K><V><P><L><K><Q><G><R><S><L><M><D><W><I><R><L><T><K><S><G><K><D><L><T><G><L><K><G><R><L><I><E><V><T><E><E><E><L><K><K><H><N><K><K><D><D><C><W><I><C><I><R><G><F><V><Y><N><V><S><P><Y><M><E><Y><H><P><G><G><E><D><E><L><M><R><A><A><G><S><D><G><T><E><L... | NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, ... | Q7L1T6 |
O60687 | SRPX2_HUMAN | Sushi-repeat protein upregulated in leukemia | Homo | <M><A><S><Q><L><T><Q><R><G><A><L><F><L><L><F><F><L><T><P><A><V><T><P><T><W><Y><A><G><S><G><Y><Y><P><D><E><S><Y><N><E><V><Y><A><E><E><V><P><Q><A><P><A><L><D><Y><R><V><P><R><W><C><Y><T><L><N><I><Q><D><G><E><A><T><C><Y><S><P><K><G><G><N><Y><H><S><S><L><G><T><R><C><E><L><S><C><D><R><G><F><R><L><I><G><R><R><S><V><Q><C><L><P... | Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogen... | O60687 |
Q8N2F6 | ARM10_HUMAN | Splicing variant involved in hepatocarcinogenesis protein | Homo | <M><G><G><P><R><G><A><G><W><V><A><A><G><L><L><L><G><A><G><A><C><Y><C><I><Y><R><L><T><R><G><R><R><R><G><D><R><E><L><G><I><R><S><S><K><S><A><G><A><L><E><E><G><T><S><E><G><Q><L><C><G><R><S><A><R><P><Q><T><G><G><T><W><E><S><Q><W><S><K><T><S><Q><P><E><D><L><T><D><G><S><Y><D><D><V><L><N><A><E><Q><L><Q><K><L><L><Y><L><L><E><S... | May play a role in cell survival and cell growth. May suppress the transcriptional activity of p53/TP53.<BOP> | Q8N2F6 |
P63129 | VPK24_HUMAN | Proteinase | Homo | <W><A><S><Q><V><S><E><N><R><P><V><C><K><A><I><I><Q><G><K><Q><F><E><G><L><V><D><T><G><A><D><V><S><I><I><A><L><N><Q><W><P><K><N><W><P><K><Q><K><A><V><T><G><L><V><G><I><G><T><A><S><E><V><Y><Q><S><T><E><I><L><H><C><L><G><P><D><N><Q><E><S><T><V><Q><P><M><I><T><S><I><P><L><N><L><W><G><R><D><L><L><Q><Q><W><G><A><E><I><T><M><P... | Retroviral proteases have roles in processing of the primary translation products and the maturation of the viral particle. Endogenous Pro proteins may have kept, lost or modified their original function during evolution. This endogenous protein has retained most of the characteristics of retroviral proteases.<BOP> | P63129 |
Q9HBE5 | IL21R_HUMAN | Novel interleukin receptor | Homo | <M><P><R><G><W><A><A><P><L><L><L><L><L><L><Q><G><G><W><G><C><P><D><L><V><C><Y><T><D><Y><L><Q><T><V><I><C><I><L><E><M><W><N><L><H><P><S><T><L><T><L><T><W><Q><D><Q><Y><E><E><L><K><D><E><A><T><S><C><S><L><H><R><S><A><H><N><A><T><H><A><T><Y><T><C><H><M><D><V><F><H><F><M><A><D><D><I><F><S><V><N><I><T><D><Q><S><G><N><Y><S><Q... | This is a receptor for interleukin-21.<BOP> | Q9HBE5 |
P05981 | HEPS_HUMAN | Serine protease hepsin catalytic chain | Homo | <M><A><Q><K><E><G><G><R><T><V><P><C><C><S><R><P><K><V><A><A><L><T><A><G><T><L><L><L><L><T><A><I><G><A><A><S><W><A><I><V><A><V><L><L><R><S><D><Q><E><P><L><Y><P><V><Q><V><S><S><A><D><A><R><L><M><V><F><D><K><T><E><G><T><W><R><L><L><C><S><S><R><S><N><A><R><V><A><G><L><S><C><E><E><M><G><F><L><R><A><L><T><H><S><E><L><D><V><R... | Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL . Plays a role in cell growth and maintenance of cell morphology . Plays a role in the proteolytic processing of ACE2 . Mediates the proteolytic cleavage of urinary UMOD that... | P05981 |
Q96CF2 | CHM4C_HUMAN | Vacuolar protein sorting-associated protein 32-3 | Homo | <M><S><K><L><G><K><F><F><K><G><G><G><S><S><K><S><R><A><A><P><S><P><Q><E><A><L><V><R><L><R><E><T><E><E><M><L><G><K><K><Q><E><Y><L><E><N><R><I><Q><R><E><I><A><L><A><K><K><H><G><T><Q><N><K><R><A><A><L><Q><A><L><K><R><K><K><R><F><E><K><Q><L><T><Q><I><D><G><T><L><S><T><I><E><F><Q><R><E><A><L><E><N><S><H><T><N><T><E><V><L><R... | Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membr... | Q96CF2 |
Q8NGK1 | O51G1_HUMAN | Olfactory receptor OR11-29 | Homo | <M><T><I><L><L><N><S><S><L><Q><R><A><T><F><F><L><T><G><F><Q><G><L><E><G><L><H><G><W><I><S><I><P><F><C><F><I><Y><L><T><V><I><L><G><N><L><T><I><L><H><V><I><C><T><D><A><T><L><H><G><P><M><Y><Y><F><L><G><M><L><A><V><T><D><L><G><L><C><L><S><T><L><P><T><V><L><G><I><F><W><F><D><T><R><E><I><G><I><P><A><C><F><T><Q><L><F><F><I><H... | Odorant receptor.<BOP> | Q8NGK1 |
O75143 | ATG13_HUMAN | Autophagy-related protein 13 | Homo | <M><E><T><D><L><N><S><Q><D><R><K><D><L><D><K><F><I><K><F><F><A><L><K><T><V><Q><V><I><V><Q><A><R><L><G><E><K><I><C><T><R><S><S><S><S><P><T><G><S><D><W><F><N><L><A><I><K><D><I><P><E><V><T><H><E><A><K><K><A><L><A><G><Q><L><P><A><V><G><R><S><M><C><V><E><I><S><L><K><T><S><E><G><D><S><M><E><L><E><I><W><C><L><E><M><N><E><K><C... | Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the ... | O75143 |
Q8TAG6 | VEXIN_HUMAN | Vexin | Homo | <M><M><H><Q><I><Y><S><C><S><D><E><N><I><E><V><F><T><T><V><I><P><S><K><V><S><S><P><A><R><R><R><A><K><S><S><Q><H><L><L><T><K><N><V><V><I><E><S><D><L><Y><T><H><Q><P><L><E><L><L><P><H><R><G><D><R><R><D><P><G><D><R><R><R><F><G><R><L><Q><T><A><R><P><P><T><A><H><P><A><K><A><S><A><R><P><V><G><I><S><E><P><K><T><S><N><L><C><G><N... | Required for neurogenesis in the neural plate and retina. Strongly cooperates with neural bHLH factors to promote neurogenesis.<BOP> | Q8TAG6 |
Q86UR1 | NOXA1_HUMAN | p51-nox | Homo | <M><A><S><L><G><D><L><V><R><A><W><H><L><G><A><Q><A><V><D><R><G><D><W><A><R><A><L><H><L><F><S><G><V><P><A><P><P><A><R><L><C><F><N><A><G><C><V><H><L><L><A><G><D><P><E><A><A><L><R><A><F><D><Q><A><V><T><K><D><T><C><M><A><V><G><F><F><Q><R><G><V><A><N><F><Q><L><A><R><F><Q><E><A><L><S><D><F><W><L><A><L><E><Q><L><R><G><H><A><A... | Functions as an activator of NOX1, a superoxide-producing NADPH oxidase. Functions in the production of reactive oxygen species (ROS) which participate in a variety of biological processes including host defense, hormone biosynthesis, oxygen sensing and signal transduction. May also activate CYBB/gp91phox and NOX3.<BOP... | Q86UR1 |
Q96P31 | FCRL3_HUMAN | SH2 domain-containing phosphatase anchor protein 2 | Homo | <M><L><L><W><L><L><L><L><I><L><T><P><G><R><E><Q><S><G><V><A><P><K><A><V><L><L><L><N><P><P><W><S><T><A><F><K><G><E><K><V><A><L><I><C><S><S><I><S><H><S><L><A><Q><G><D><T><Y><W><Y><H><D><E><K><L><L><K><I><K><H><D><K><I><Q><I><T><E><P><G><N><Y><Q><C><K><T><R><G><S><S><L><S><D><A><V><H><V><E><F><S><P><D><W><L><I><L><Q><A><L... | Promotes TLR9-induced B-cell proliferation, activation and survival but inhibits antibody production and suppresses plasma cell differentiation. Enhances activation of NF-kappa-B and MAPK signaling pathways in TLR9 stimulated B-cells . Has inhibitory potentional on B-cell receptor (BCR)-mediated signaling, possibly thr... | Q96P31 |
Q86UQ0 | ZN589_HUMAN | Stem cell zinc finger protein 1 | Homo | <M><W><A><P><R><E><Q><L><L><G><W><T><A><E><A><L><P><A><K><D><S><A><W><P><W><E><E><K><P><R><Y><L><G><P><V><T><F><E><D><V><A><V><L><F><T><E><A><E><W><K><R><L><S><L><E><Q><R><N><L><Y><K><E><V><M><L><E><N><L><R><N><L><V><S><L><A><E><S><K><P><E><V><H><T><C><P><S><C><P><L><A><F><G><S><Q><Q><F><L><S><Q><D><E><L><H><N><H><P><I... | May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.<BOP> | Q86UQ0 |
P01222 | TSHB_HUMAN | Thyrotropin beta chain | Homo | <M><T><A><L><F><L><M><S><M><L><F><G><L><T><C><G><Q><A><M><S><F><C><I><P><T><E><Y><T><M><H><I><E><R><R><E><C><A><Y><C><L><T><I><N><T><T><I><C><A><G><Y><C><M><T><R><D><I><N><G><K><L><F><L><P><K><Y><A><L><S><Q><D><V><C><T><Y><R><D><F><I><Y><R><T><V><E><I><P><G><C><P><L><H><V><A><P><Y><F><S><Y><P><V><A><L><S><C><K><C><G><K... | Indispensable for the control of thyroid structure and metabolism.<BOP> | P01222 |
Q6DD87 | ZN787_HUMAN | TTF-I-interacting peptide 20 | Homo | <M><E><L><R><E><E><A><W><S><P><G><P><L><D><S><E><D><Q><Q><M><A><S><H><E><N><P><V><D><I><L><I><M><D><D><D><D><V><P><S><W><P><P><T><K><L><S><P><P><Q><S><A><P><P><A><G><P><P><P><R><P><R><P><P><A><P><Y><I><C><N><E><C><G><K><S><F><S><H><W><S><K><L><T><R><H><Q><R><T><H><T><G><E><R><P><N><A><C><A><D><C><G><K><T><F><S><Q><S><S... | May be involved in transcriptional regulation.<BOP> | Q6DD87 |
P09488 | GSTM1_HUMAN | GTH4 | Homo | <M><P><M><I><L><G><Y><W><D><I><R><G><L><A><H><A><I><R><L><L><L><E><Y><T><D><S><S><Y><E><E><K><K><Y><T><M><G><D><A><P><D><Y><D><R><S><Q><W><L><N><E><K><F><K><L><G><L><D><F><P><N><L><P><Y><L><I><D><G><A><H><K><I><T><Q><S><N><A><I><L><C><Y><I><A><R><K><H><N><L><C><G><E><T><E><E><E><K><I><R><V><D><I><L><E><N><Q><T><M><D><N... | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) . Participates in the formation of novel hepoxilin regioisomers .<BOP> | P09488 |
Q6ZPB5 | SDIM1_HUMAN | Stress-responsive DNAJB4-interacting membrane protein 1 | Homo | <M><W><P><A><P><C><S><V><G><R><L><L><I><F><F><M><C><S><S><S><G><Y><V><V><Q><G><C><G><P><S><P><G><A><R><T><T><L><G><S><P><L><S><L><W><S><I><K><T><P><S><H><I><F><C><T><R><R><A><I><N><L><G><F><P><S><P><P><L><V><Q><L><I><F><W><S><L><N><A><G><L><D><L><Y><L><C><L><I><S><S><C><G><F><S><Q><V><F><W><P><V><E><A><F><C><S><F><S><L... | Promotes neuronal cells survival to stress conditions.<BOP> | Q6ZPB5 |
P0C7V7 | SC11B_HUMAN | SEC11-like protein 2 | Homo | <M><N><K><W><R><L><Y><Y><Q><V><L><N><F><G><M><I><V><S><S><A><L><M><I><W><K><G><L><M><V><I><T><G><S><E><S><P><I><V><L><L><S><G><S><M><E><P><A><F><H><R><G><Y><L><L><F><L><T><N><R><V><E><D><P><I><R><V><G><E><I><A><V><L><R><I><E><G><R><K><I><P><I><V><H><R><V><L><K><I><H><E><K><Q><N><G><H><I><K><F><L><T><K><G><D><N><N><A><V... | Putative component of some signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.<BOP> | P0C7V7 |
P60852 | ZP1_HUMAN | Processed zona pellucida sperm-binding protein 1 | Homo | <M><A><G><G><S><A><T><T><W><G><Y><P><V><A><L><L><L><L><V><A><T><L><G><L><G><R><W><L><Q><P><D><P><G><L><P><G><L><R><H><S><Y><D><C><G><I><K><G><M><Q><L><L><V><F><P><R><P><G><Q><T><L><R><F><K><V><V><D><E><F><G><N><R><F><D><V><N><N><C><S><I><C><Y><H><W><V><T><S><R><P><Q><E><P><A><V><F><S><A><D><Y><R><G><C><H><V><L><E><K><D... | Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellu... | P60852 |
P60014 | KR10A_HUMAN | Keratin-associated protein 18.10 | Homo | <M><A><A><S><T><M><S><I><C><S><S><A><C><T><D><S><W><R><V><V><D><C><P><E><S><C><C><E><P><C><C><C><A><P><A><P><S><L><T><L><V><C><T><P><V><S><C><V><S><S><P><C><C><Q><T><A><C><E><P><S><A><C><Q><S><G><Y><T><S><S><C><T><T><P><C><Y><Q><Q><S><S><C><Q><P><D><C><C><T><S><S><P><C><Q><Q><A><C><C><V><P><V><C><C><V><P><V><C><C><V><P... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60014 |
Q92688 | AN32B_HUMAN | Silver-stainable protein SSP29 | Homo | <M><D><M><K><R><R><I><H><L><E><L><R><N><R><T><P><A><A><V><R><E><L><V><L><D><N><C><K><S><N><D><G><K><I><E><G><L><T><A><E><F><V><N><L><E><F><L><S><L><I><N><V><G><L><I><S><V><S><N><L><P><K><L><P><K><L><K><K><L><E><L><S><E><N><R><I><F><G><G><L><D><M><L><A><E><K><L><P><N><L><T><H><L><N><L><S><G><N><K><L><K><D><I><S><T><L><E... | (Microbial infection) Plays an essential role in influenza A and B viral genome replication . Also plays a role in foamy virus mRNA export from the nucleus to the cytoplasm .<BOP> | Q92688 |
A6NNE9 | MARHB_HUMAN | RING-type E3 ubiquitin transferase MARCHF11 | Homo | <M><S><F><E><G><G><H><G><G><S><R><C><R><G><A><E><S><G><D><A><E><P><P><P><Q><P><P><P><P><P><P><P><T><P><P><P><G><E><P><A><P><V><P><A><A><P><R><Y><L><P><P><L><P><A><S><P><E><T><P><E><R><A><A><G><P><S><E><P><L><G><E><V><A><P><R><C><R><G><A><D><E><L><P><P><P><P><L><P><L><Q><P><A><G><Q><E><V><A><A><A><G><D><S><G><E><G><P><R... | E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermati... | A6NNE9 |
Q9P2M4 | TBC14_HUMAN | TBC1 domain family member 14 | Homo | <M><T><D><G><K><L><S><T><S><T><N><G><V><A><F><M><G><I><L><D><G><R><P><G><N><P><L><Q><N><L><Q><H><V><N><L><K><A><P><R><L><L><S><A><P><E><Y><G><P><K><L><K><L><R><A><L><E><D><R><H><S><L><Q><S><V><D><S><G><I><P><T><L><E><I><G><N><P><E><P><V><P><C><S><A><V><H><V><R><R><K><Q><S><D><S><D><L><I><P><E><R><A><F><Q><S><A><C><A><L... | Plays a role in the regulation of starvation-induced autophagosome formation . Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy.<BOP> | Q9P2M4 |
Q9BTE7 | DCNL5_HUMAN | Squamous cell carcinoma-related oncogene 5 | Homo | <M><P><V><K><K><K><R><K><S><P><G><V><A><A><A><V><A><E><D><G><G><L><K><K><C><K><I><S><S><Y><C><R><S><Q><P><P><A><R><L><I><S><G><E><E><H><F><S><S><K><K><C><L><A><W><F><Y><E><Y><A><G><P><D><E><V><V><G><P><E><G><M><E><K><F><C><E><D><I><G><V><E><P><E><N><I><I><M><L><V><L><A><W><K><L><E><A><E><S><M><G><F><F><T><K><E><E><W><L... | Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) . May play a role in DNA damage response and may participate ... | Q9BTE7 |
Q8IWB1 | IPRI_HUMAN | Protein DANGER | Homo | <M><A><M><G><L><F><R><V><C><L><V><V><V><T><A><I><I><N><H><P><L><L><F><P><R><E><N><A><T><V><P><E><N><E><E><E><I><I><R><K><M><Q><A><H><Q><E><K><L><Q><L><E><Q><L><R><L><E><E><E><V><A><R><L><A><A><E><K><E><A><L><E><Q><V><A><E><E><G><R><Q><Q><N><E><T><R><V><A><W><D><L><W><S><T><L><C><M><I><L><F><L><M><I><E><V><W><R><Q><D><H... | Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.<BOP> | Q8IWB1 |
A0A0A0MRZ8 | KVD11_HUMAN | Immunoglobulin kappa variable 3D-11 | Homo | <M><E><A><P><A><Q><L><L><F><L><L><L><L><W><L><P><D><T><T><G><E><I><V><L><T><Q><S><P><A><T><L><S><L><S><P><G><E><R><A><T><L><S><C><R><A><S><Q><S><V><S><S><Y><L><A><W><Y><Q><Q><K><P><G><Q><A><P><R><L><L><I><Y><D><A><S><N><R><A><T><G><I><P><A><R><F><S><G><S><G><P><G><T><D><F><T><L><T><I><S><S><L><E><P><E><D><F><A><V><Y><Y... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0A0MRZ8 |
Q8NFP7 | NUD10_HUMAN | hAps2 | Homo | <M><K><C><K><P><N><Q><T><R><T><Y><D><P><E><G><F><K><K><R><A><A><C><L><C><F><R><S><E><R><E><D><E><V><L><L><V><S><S><S><R><Y><P><D><R><W><I><V><P><G><G><G><M><E><P><E><E><E><P><G><G><A><A><V><R><E><V><Y><E><E><A><G><V><K><G><K><L><G><R><L><L><G><V><F><E><Q><N><Q><D><P><K><H><R><T><Y><V><Y><V><L><T><V><T><E><L><L><E><D><W... | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP ... | Q8NFP7 |
P01860 | IGHG3_HUMAN | Ig gamma-3 chain C region | Homo | <A><S><T><K><G><P><S><V><F><P><L><A><P><C><S><R><S><T><S><G><G><T><A><A><L><G><C><L><V><K><D><Y><F><P><E><P><V><T><V><S><W><N><S><G><A><L><T><S><G><V><H><T><F><P><A><V><L><Q><S><S><G><L><Y><S><L><S><S><V><V><T><V><P><S><S><S><L><G><T><Q><T><Y><T><C><N><V><N><H><K><P><S><N><T><K><V><D><K><R><V><E><L><K><T><P><L><G><D><T... | Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the cl... | P01860 |
Q5T2D2 | TRML2_HUMAN | Triggering receptor expressed on myeloid cells-like protein 2 | Homo | <M><A><P><A><F><L><L><L><L><L><L><W><P><Q><G><C><V><S><G><P><S><A><D><S><V><Y><T><K><V><R><L><L><E><G><E><T><L><S><V><Q><C><S><Y><K><G><Y><K><N><R><V><E><G><K><V><W><C><K><I><R><K><K><K><C><E><P><G><F><A><R><V><W><V><K><G><P><R><Y><L><L><Q><D><D><A><Q><A><K><V><V><N><I><T><M><V><A><L><K><L><Q><D><S><G><R><Y><W><C><M><R... | Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.<BOP> | Q5T2D2 |
Q8TAD4 | ZNT5_HUMAN | ZnT-like transporter 1 | Homo | <M><E><E><K><Y><G><G><D><V><L><A><G><P><G><G><G><G><G><L><G><P><V><D><V><P><S><A><R><L><T><K><Y><I><V><L><L><C><F><T><K><F><L><K><A><V><G><L><F><E><S><Y><D><L><L><K><A><V><H><I><V><Q><F><I><F><I><L><K><L><G><T><A><F><F><M><V><L><F><Q><K><P><F><S><S><G><K><T><I><T><K><H><Q><W><I><K><I><F><K><H><A><V><A><G><C><I><I><S><L... | Zinc ion:proton antiporter mediating influx and efflux of zinc at the plasma membrane.<BOP> | Q8TAD4 |
Q96CT7 | CC124_HUMAN | Coiled-coil domain-containing protein 124 | Homo | <M><P><K><K><F><Q><G><E><N><T><K><S><A><A><A><R><A><R><R><A><E><A><K><A><A><A><D><A><K><K><Q><K><E><L><E><D><A><Y><W><K><D><D><D><K><H><V><M><R><K><E><Q><R><K><E><E><K><E><K><R><R><L><D><Q><L><E><R><K><K><E><T><Q><R><L><L><E><E><E><D><S><K><L><K><G><G><K><A><P><R><V><A><T><S><S><K><V><T><R><A><Q><I><E><D><T><L><R><R><D... | Required for proper progression of late cytokinetic stages.<BOP> | Q96CT7 |
Q6UUV7 | CRTC3_HUMAN | Transducer of regulated cAMP response element-binding protein 3 | Homo | <M><A><A><S><P><G><S><G><S><A><N><P><R><K><F><S><E><K><I><A><L><H><T><Q><R><Q><A><E><E><T><R><A><F><E><Q><L><M><T><D><L><T><L><S><R><V><Q><F><Q><K><L><Q><Q><L><R><L><T><Q><Y><H><G><G><S><L><P><N><V><S><Q><L><R><S><S><A><S><E><F><Q><P><S><F><H><Q><A><D><N><V><R><G><T><R><H><H><G><L><V><E><R><P><S><R><N><R><F><H><P><L><H... | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CR... | Q6UUV7 |
Q6UWP2 | DHR11_HUMAN | Short-chain dehydrogenase/reductase family 24C member 1 | Homo | <M><A><R><P><G><M><E><R><W><R><D><R><L><A><L><V><T><G><A><S><G><G><I><G><A><A><V><A><R><A><L><V><Q><Q><G><L><K><V><V><G><C><A><R><T><V><G><N><I><E><E><L><A><A><E><C><K><S><A><G><Y><P><G><T><L><I><P><Y><R><C><D><L><S><N><E><E><D><I><L><S><M><F><S><A><I><R><S><Q><H><S><G><V><D><I><C><I><N><N><A><G><L><A><R><P><D><T><L><L... | Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity t... | Q6UWP2 |
Q16342 | PDCD2_HUMAN | Zinc finger protein Rp-8 | Homo | <M><A><A><A><G><A><R><P><V><E><L><G><F><A><E><S><A><P><A><W><R><L><R><S><E><Q><F><P><S><K><V><G><G><R><P><A><W><L><G><A><A><G><L><P><G><P><Q><A><L><A><C><E><L><C><G><R><P><L><S><F><L><L><Q><V><Y><A><P><L><P><G><R><P><D><A><F><H><R><C><I><F><L><F><C><C><R><E><Q><P><C><C><A><G><L><R><V><F><R><N><Q><L><P><R><K><N><D><F><Y... | May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.<BOP> | Q16342 |
O15315 | RA51B_HUMAN | RAD51-like protein 1 | Homo | <M><G><S><K><K><L><K><R><V><G><L><S><Q><E><L><C><D><R><L><S><R><H><Q><I><L><T><C><Q><D><F><L><C><L><S><P><L><E><L><M><K><V><T><G><L><S><Y><R><G><V><H><E><L><L><C><M><V><S><R><A><C><A><P><K><M><Q><T><A><Y><G><I><K><A><Q><R><S><A><D><F><S><P><A><F><L><S><T><T><L><S><A><L><D><E><A><L><H><G><G><V><A><C><G><S><L><T><E><I><T... | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Pa... | O15315 |
A0A087WT03 | TVAZ1_HUMAN | T cell receptor alpha variable 26-1 | Homo | <M><R><L><V><A><R><V><T><V><F><L><T><F><G><T><I><I><D><A><K><T><T><Q><P><T><S><M><D><C><A><E><G><R><A><A><N><L><P><C><N><H><S><T><I><S><G><N><E><Y><V><Y><W><Y><R><Q><I><H><S><Q><G><P><Q><Y><I><I><H><G><L><K><N><N><E><T><N><E><M><A><S><L><I><I><T><E><D><R><K><S><S><T><L><I><L><P><H><A><T><L><R><D><T><A><V><Y><Y><C><I><V... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A087WT03 |
O95388 | CCN4_HUMAN | Wnt-1-induced secreted protein | Homo | <M><R><W><F><L><P><W><T><L><A><A><V><T><A><A><A><A><S><T><V><L><A><T><A><L><S><P><A><P><T><T><M><D><F><T><P><A><P><L><E><D><T><S><S><R><P><Q><F><C><K><W><P><C><E><C><P><P><S><P><P><R><C><P><L><G><V><S><L><I><T><D><G><C><E><C><C><K><M><C><A><Q><Q><L><G><D><N><C><T><E><A><A><I><C><D><P><H><R><G><L><Y><C><D><Y><S><G><D><R... | Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs... | O95388 |
Q6P988 | NOTUM_HUMAN | hNOTUM | Homo | <M><G><R><G><V><R><V><L><L><L><L><S><L><L><H><C><A><G><G><S><E><G><R><K><T><W><R><R><R><G><Q><Q><P><P><P><P><P><R><T><E><A><A><P><A><A><G><Q><P><V><E><S><F><P><L><D><F><T><A><V><E><G><N><M><D><S><F><M><A><Q><V><K><S><L><A><Q><S><L><Y><P><C><S><A><Q><Q><L><N><E><D><L><R><L><H><L><L><L><N><T><S><V><T><C><N><D><G><S><P><A... | Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors .<BOP> | Q6P988 |
Q9NPF2 | CHSTB_HUMAN | Chondroitin 4-sulfotransferase 1 | Homo | <M><K><P><A><L><L><E><V><M><R><M><N><R><I><C><R><M><V><L><A><T><C><L><G><S><F><I><L><V><I><F><Y><F><Q><S><M><L><H><P><V><M><R><R><N><P><F><G><V><D><I><C><C><R><K><G><S><R><S><P><L><Q><E><L><Y><N><P><I><Q><L><E><L><S><N><T><A><V><L><H><Q><M><R><R><D><Q><V><T><D><T><C><R><A><N><S><A><T><S><R><K><R><R><V><L><T><P><N><D><L... | Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermata... | Q9NPF2 |
P78346 | RPP30_HUMAN | RNase P subunit 2 | Homo | <M><A><V><F><A><D><L><D><L><R><A><G><S><D><L><K><A><L><R><G><L><V><E><T><A><A><H><L><G><Y><S><V><V><A><I><N><H><I><V><D><F><K><E><K><K><Q><E><I><E><K><P><V><A><V><S><E><L><F><T><T><L><P><I><V><Q><G><K><S><R><P><I><K><I><L><T><R><L><T><I><I><V><S><D><P><S><H><C><N><V><L><R><A><T><S><S><R><A><R><L><Y><D><V><V><A><V><F><P... | Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends . Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences .<BOP> | P78346 |
Q86VR8 | FJX1_HUMAN | Four-jointed protein homolog | Homo | <M><G><R><R><M><R><G><A><A><A><T><A><G><L><W><L><L><A><L><G><S><L><L><A><L><W><G><G><L><L><P><P><R><T><E><L><P><A><S><R><P><P><E><D><R><L><P><R><R><P><A><R><S><G><G><P><A><P><A><P><R><F><P><L><P><P><P><L><A><W><D><A><R><G><G><S><L><K><T><F><R><A><L><L><T><L><A><A><G><A><D><G><P><P><R><Q><S><R><S><E><P><R><W><H><V><S><A... | Acts as an inhibitor of dendrite extension and branching.<BOP> | Q86VR8 |
Q15726 | KISS1_HUMAN | Kisspeptin-10 | Homo | <M><N><S><L><V><S><W><Q><L><L><L><F><L><C><A><T><H><F><G><E><P><L><E><K><V><A><S><V><G><N><S><R><P><T><G><Q><Q><L><E><S><L><G><L><L><A><P><G><E><Q><S><L><P><C><T><E><R><K><P><A><A><T><A><R><L><S><R><R><G><T><S><L><S><P><P><P><E><S><S><G><S><P><Q><Q><P><G><L><S><A><P><H><S><R><Q><I><P><A><P><Q><G><A><V><L><V><Q><R><E><K... | Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Ac... | Q15726 |
P01705 | LV223_HUMAN | Ig lambda chain V-II region NEI | Homo | <M><A><W><A><L><L><L><L><T><L><L><T><Q><D><T><G><S><W><A><Q><S><A><L><T><Q><P><A><S><V><S><G><S><P><G><Q><S><I><T><I><S><C><T><G><T><S><S><D><V><G><S><Y><N><L><V><S><W><Y><Q><Q><H><P><G><K><A><P><K><L><M><I><Y><E><G><S><K><R><P><S><G><V><S><N><R><F><S><G><S><K><S><G><N><T><A><S><L><T><I><S><G><L><Q><A><E><D><E><A><D><Y... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01705 |
P60368 | KR102_HUMAN | Keratin-associated protein 18.2 | Homo | <M><A><A><S><T><M><S><I><C><S><S><A><C><T><N><S><W><Q><V><D><D><C><P><E><S><C><C><E><L><P><C><G><T><P><S><C><C><A><P><A><P><C><L><T><L><V><C><T><P><V><S><C><V><S><S><P><C><C><Q><A><A><C><E><P><S><A><C><Q><S><G><C><T><S><S><C><T><P><S><C><C><Q><Q><S><S><C><Q><P><A><C><C><T><S><S><P><C><Q><Q><A><C><C><V><P><V><C><C><K><P... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60368 |
P35268 | RL22_HUMAN | Large ribosomal subunit protein eL22 | Homo | <M><A><P><V><K><K><L><V><V><K><G><G><K><K><K><K><Q><V><L><K><F><T><L><D><C><T><H><P><V><E><D><G><I><M><D><A><A><N><F><E><Q><F><L><Q><E><R><I><K><V><N><G><K><A><G><N><L><G><G><G><V><V><T><I><E><R><S><K><S><K><I><T><V><T><S><E><V><P><F><S><K><R><Y><L><K><Y><L><T><K><K><Y><L><K><K><N><N><L><R><D><W><L><R><V><V><A><N><S><K... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP> | P35268 |
Q9H6T0 | ESRP2_HUMAN | RNA-binding protein 35B | Homo | <M><T><P><P><P><P><P><P><P><P><P><G><P><D><P><A><A><D><P><A><A><D><P><C><P><W><P><G><S><L><V><V><L><F><G><A><T><A><G><A><L><G><R><D><L><G><S><D><E><T><D><L><I><L><L><V><W><Q><V><V><E><P><R><S><R><Q><V><G><T><L><H><K><S><L><V><R><A><E><A><A><A><L><S><T><Q><C><R><E><A><S><G><L><S><A><D><S><L><A><R><A><E><P><L><D><K><V><L... | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchyma... | Q9H6T0 |
Q9H0K4 | RSH6A_HUMAN | Radial spoke head-like protein 1 | Homo | <M><G><D><L><P><P><Y><P><E><R><P><A><Q><Q><P><P><G><R><R><T><S><Q><A><S><Q><R><R><H><S><R><D><Q><A><Q><A><L><A><A><D><P><E><E><R><Q><Q><I><P><P><D><A><Q><R><N><A><P><G><W><S><Q><R><G><S><L><S><Q><Q><E><N><L><L><M><P><Q><V><F><Q><A><E><E><A><R><L><G><G><M><E><Y><P><S><V><N><T><G><F><P><S><E><F><Q><P><Q><P><Y><S><D><E><S... | Essential for sperm flagellar assembly and male fertility.<BOP> | Q9H0K4 |
Q8NG78 | OR8G5_HUMAN | Olfactory receptor OR11-298 | Homo | <M><I><I><Y><K><Q><G><I><T><F><L><Q><K><E><N><N><N><T><I><H><L><N><T><M><F><F><L><S><P><A><E><T><H><Q><R><M><A><A><E><N><H><S><F><V><T><K><F><I><L><V><G><L><T><E><K><S><E><L><Q><L><P><L><F><L><V><F><L><G><I><Y><V><V><T><V><L><G><N><L><G><M><I><T><L><I><G><L><S><S><H><L><H><T><P><M><Y><C><F><L><S><S><L><S><F><I><D><F><C... | Odorant receptor.<BOP> | Q8NG78 |
Q7Z7D3 | VTCN1_HUMAN | T-cell costimulatory molecule B7x | Homo | <M><A><S><L><G><Q><I><L><F><W><S><I><I><S><I><I><I><I><L><A><G><A><I><A><L><I><I><G><F><G><I><S><G><R><H><S><I><T><V><T><T><V><A><S><A><G><N><I><G><E><D><G><I><L><S><C><T><F><E><P><D><I><K><L><S><D><I><V><I><Q><W><L><K><E><G><V><L><G><L><V><H><E><F><K><E><G><K><D><E><L><S><E><Q><D><E><M><F><R><G><R><T><A><V><F><A><D><Q... | Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated anti... | Q7Z7D3 |
P49419 | AL7A1_HUMAN | Delta1-piperideine-6-carboxylate dehydrogenase | Homo | <M><W><R><L><P><R><A><L><C><V><H><A><A><K><T><S><K><L><S><G><P><W><S><R><P><A><A><F><M><S><T><L><L><I><N><Q><P><Q><Y><A><W><L><K><E><L><G><L><R><E><E><N><E><G><V><Y><N><G><S><W><G><G><R><G><E><V><I><T><T><Y><C><P><A><N><N><E><P><I><A><R><V><R><Q><A><S><V><A><D><Y><E><E><T><V><K><K><A><R><E><A><W><K><I><W><A><D><I><P><A... | Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism.<BOP> | P49419 |
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