accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P28908 | TNR8_HUMAN | Lymphocyte activation antigen CD30 | Homo | <M><R><V><L><L><A><A><L><G><L><L><F><L><G><A><L><R><A><F><P><Q><D><R><P><F><E><D><T><C><H><G><N><P><S><H><Y><Y><D><K><A><V><R><R><C><C><Y><R><C><P><M><G><L><F><P><T><Q><Q><C><P><Q><R><P><T><D><C><R><K><Q><C><E><P><D><Y><Y><L><D><E><A><D><R><C><T><A><C><V><T><C><S><R><D><D><L><V><E><K><T><P><C><A><W><N><S><S><R><V><C><E... | Receptor for TNFSF8/CD30L . May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B .<BOP> | P28908 |
Q9BPZ3 | PAIP2_HUMAN | Polyadenylate-binding protein-interacting protein 2 | Homo | <M><K><D><P><S><R><S><S><T><S><P><S><I><I><N><E><D><V><I><I><N><G><H><S><H><E><D><D><N><P><F><A><E><Y><M><W><M><E><N><E><E><E><F><N><R><Q><I><E><E><E><L><W><E><E><E><F><I><E><R><C><F><Q><E><M><L><E><E><E><E><E><H><E><W><F><I><P><A><R><D><L><P><Q><T><M><D><Q><I><Q><D><Q><F><N><D><L><V><I><S><D><G><S><S><L><E><D><L><V><V... | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption ... | Q9BPZ3 |
O14950 | ML12B_HUMAN | SHUJUN-1 | Homo | <M><S><S><K><K><A><K><T><K><T><T><K><K><R><P><Q><R><A><T><S><N><V><F><A><M><F><D><Q><S><Q><I><Q><E><F><K><E><A><F><N><M><I><D><Q><N><R><D><G><F><I><D><K><E><D><L><H><D><M><L><A><S><L><G><K><N><P><T><D><A><Y><L><D><A><M><M><N><E><A><P><G><P><I><N><F><T><M><F><L><T><M><F><G><E><K><L><N><G><T><D><P><E><D><V><I><R><N><A><F... | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion.<BOP> | O14950 |
Q9Y6E0 | STK24_HUMAN | Mammalian STE20-like protein kinase 3 C-terminal | Homo | <M><D><S><R><A><Q><L><W><G><L><A><L><N><K><R><R><A><T><L><P><H><P><G><G><S><T><N><L><K><A><D><P><E><E><L><F><T><K><L><E><K><I><G><K><G><S><F><G><E><V><F><K><G><I><D><N><R><T><Q><K><V><V><A><I><K><I><I><D><L><E><E><A><E><D><E><I><E><D><I><Q><Q><E><I><T><V><L><S><Q><C><D><S><P><Y><V><T><K><Y><Y><G><S><Y><L><K><D><T><K><L... | Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative... | Q9Y6E0 |
Q53H82 | LACB2_HUMAN | Beta-lactamase-like protein 2 | Homo | <M><A><A><V><L><Q><R><V><E><R><L><S><N><R><V><V><R><V><L><G><C><N><P><G><P><M><T><L><Q><G><T><N><T><Y><L><V><G><T><G><P><R><R><I><L><I><D><T><G><E><P><A><I><P><E><Y><I><S><C><L><K><Q><A><L><T><E><F><N><T><A><I><Q><E><I><V><V><T><H><W><H><R><D><H><S><G><G><I><G><D><I><C><K><S><I><N><N><D><T><T><Y><C><I><K><K><L><P><R><N... | Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.<BOP> | Q53H82 |
O75689 | ADAP1_HUMAN | Putative MAPK-activating protein PM25 | Homo | <M><A><K><E><R><R><R><A><V><L><E><L><L><Q><R><P><G><N><A><R><C><A><D><C><G><A><P><D><P><D><W><A><S><Y><T><L><G><V><F><I><C><L><S><C><S><G><I><H><R><N><I><P><Q><V><S><K><V><K><S><V><R><L><D><A><W><E><E><A><Q><V><E><F><M><A><S><H><G><N><D><A><A><R><A><R><F><E><S><K><V><P><S><F><Y><Y><R><P><T><P><S><D><C><Q><L><L><R><E><Q... | GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<BOP> | O75689 |
A0A1B0GX49 | TVB64_HUMAN | T cell receptor beta variable 6-4 | Homo | <M><S><I><R><L><L><C><C><V><A><F><S><L><L><W><A><G><P><V><T><A><G><I><T><Q><A><P><T><S><Q><I><L><A><A><G><R><S><M><T><L><R><C><T><Q><D><M><R><H><N><A><M><Y><W><Y><R><Q><D><L><G><L><G><L><R><L><I><H><Y><S><N><T><A><G><T><T><G><K><G><E><V><P><D><G><Y><S><V><S><R><A><N><T><D><D><F><P><L><T><L><A><S><A><V><P><S><Q><T><S><V... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A1B0GX49 |
P31949 | S10AB_HUMAN | Protein S100-A11, N-terminally processed | Homo | <M><A><K><I><S><S><P><T><E><T><E><R><C><I><E><S><L><I><A><V><F><Q><K><Y><A><G><K><D><G><Y><N><Y><T><L><S><K><T><E><F><L><S><F><M><N><T><E><L><A><A><F><T><K><N><Q><K><D><P><G><V><L><D><R><M><M><K><K><L><D><T><N><S><D><G><Q><L><D><F><S><E><F><L><N><L><I><G><G><L><A><M><A><C><H><D><S><F><L><K><A><V><P><S><Q><K><R><T> | Facilitates the differentiation and the cornification of keratinocytes.<BOP> | P31949 |
Q9UHI5 | LAT2_HUMAN | Solute carrier family 7 member 8 | Homo | <M><E><E><G><A><R><H><R><N><N><T><E><K><K><H><P><G><G><G><E><S><D><A><S><P><E><A><G><S><G><G><G><G><V><A><L><K><K><E><I><G><L><V><S><A><C><G><I><I><V><G><N><I><I><G><S><G><I><F><V><S><P><K><G><V><L><E><N><A><G><S><V><G><L><A><L><I><V><W><I><V><T><G><F><I><T><V><V><G><A><L><C><Y><A><E><L><G><V><T><I><P><K><S><G><G><D><Y... | Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affi... | Q9UHI5 |
P29373 | RABP2_HUMAN | Cellular retinoic acid-binding protein II | Homo | <M><P><N><F><S><G><N><W><K><I><I><R><S><E><N><F><E><E><L><L><K><V><L><G><V><N><V><M><L><R><K><I><A><V><A><A><A><S><K><P><A><V><E><I><K><Q><E><G><D><T><F><Y><I><K><T><S><T><T><V><R><T><T><E><I><N><F><K><V><G><E><E><F><E><E><Q><T><V><D><G><R><P><C><K><S><L><V><K><W><E><S><E><N><K><M><V><C><E><Q><K><L><L><K><G><E><G><P><K... | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.<BOP> | P29373 |
Q9BQ90 | KLDC3_HUMAN | Testis intracellular mediator protein | Homo | <M><L><R><W><T><V><H><L><E><G><G><P><R><R><V><N><H><A><A><V><A><V><G><H><R><V><Y><S><F><G><G><Y><C><S><G><E><D><Y><E><T><L><R><Q><I><D><V><H><I><F><N><A><V><S><L><R><W><T><K><L><P><P><V><K><S><A><I><R><G><Q><A><P><V><V><P><Y><M><R><Y><G><H><S><T><V><L><I><D><D><T><V><L><L><W><G><G><R><N><D><T><E><G><A><C><N><V><L><Y><A... | Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation . The C-degron recognized by the DesCEND pat... | Q9BQ90 |
Q8N4P3 | MESH1_HUMAN | Penta-phosphate guanosine-3'-pyrophosphohydrolase | Homo | <M><G><S><E><A><A><Q><L><L><E><A><A><D><F><A><A><R><K><H><R><Q><Q><R><R><K><D><P><E><G><T><P><Y><I><N><H><P><I><G><V><A><R><I><L><T><H><E><A><G><I><T><D><I><V><V><L><Q><A><A><L><L><H><D><T><V><E><D><T><D><T><T><L><D><E><V><E><L><H><F><G><A><Q><V><R><R><L><V><E><E><V><T><D><D><K><T><L><P><K><L><E><R><K><R><L><Q><V><E><Q... | ppGpp hydrolyzing enzyme involved in starvation response.<BOP> | Q8N4P3 |
Q7Z4H4 | ADM2_HUMAN | Intermedin-short | Homo | <M><A><R><I><P><T><A><A><L><G><C><I><S><L><L><C><L><Q><L><P><G><S><L><S><R><S><L><G><G><D><P><R><P><V><K><P><R><E><P><P><A><R><S><P><S><S><S><L><Q><P><R><H><P><A><P><R><P><V><V><W><K><L><H><R><A><L><Q><A><Q><R><G><A><G><L><A><P><V><M><G><Q><P><L><R><D><G><G><R><Q><H><S><G><P><R><R><H><S><G><P><R><R><T><Q><A><Q><L><L><R... | May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.<BOP> | Q7Z4H4 |
P38571 | LICH_HUMAN | Sterol esterase | Homo | <M><K><M><R><F><L><G><L><V><V><C><L><V><L><W><T><L><H><S><E><G><S><G><G><K><L><T><A><V><D><P><E><T><N><M><N><V><S><E><I><I><S><Y><W><G><F><P><S><E><E><Y><L><V><E><T><E><D><G><Y><I><L><C><L><N><R><I><P><H><G><R><K><N><H><S><D><K><G><P><K><P><V><V><F><L><Q><H><G><L><L><A><D><S><S><N><W><V><T><N><L><A><N><S><S><L><G><F><I... | Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol.<BOP> | P38571 |
O14718 | OPSX_HUMAN | Visual pigment-like receptor peropsin | Homo | <M><L><R><N><N><L><G><N><S><S><D><S><K><N><E><D><G><S><V><F><S><Q><T><E><H><N><I><V><A><T><Y><L><I><M><A><G><M><I><S><I><I><S><N><I><I><V><L><G><I><F><I><K><Y><K><E><L><R><T><P><T><N><A><I><I><I><N><L><A><V><T><D><I><G><V><S><S><I><G><Y><P><M><S><A><A><S><D><L><Y><G><S><W><K><F><G><Y><A><G><C><Q><V><Y><A><G><L><N><I><F... | May play a role in rpe physiology either by detecting light directly or by monitoring the concentration of retinoids or other photoreceptor-derived compounds.<BOP> | O14718 |
P54105 | ICLN_HUMAN | Reticulocyte pICln | Homo | <M><S><F><L><K><S><F><P><P><P><G><P><A><E><G><L><L><R><Q><Q><P><D><T><E><A><V><L><N><G><K><G><L><G><T><G><T><L><Y><I><A><E><S><R><L><S><W><L><D><G><S><G><L><G><F><S><L><E><Y><P><T><I><S><L><H><A><L><S><R><D><R><S><D><C><L><G><E><H><L><Y><V><M><V><N><A><K><F><E><E><E><S><K><E><P><V><A><D><E><E><E><E><D><S><D><D><D><V><E... | Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins . Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs .... | P54105 |
Q01638 | ILRL1_HUMAN | Protein ST2 | Homo | <M><G><F><W><I><L><A><I><L><T><I><L><M><Y><S><T><A><A><K><F><S><K><Q><S><W><G><L><E><N><E><A><L><I><V><R><C><P><R><Q><G><K><P><S><Y><T><V><D><W><Y><Y><S><Q><T><N><K><S><I><P><T><Q><E><R><N><R><V><F><A><S><G><Q><L><L><K><F><L><P><A><A><V><A><D><S><G><I><Y><T><C><I><V><R><S><P><T><F><N><R><T><G><Y><A><N><V><T><I><Y><K><K... | Inhibits IL-33 signaling.<BOP> | Q01638 |
Q9P270 | SLAI2_HUMAN | SLAIN motif-containing protein 2 | Homo | <M><E><D><V><N><S><N><V><N><A><D><Q><E><V><R><K><L><Q><E><L><V><K><K><L><E><K><Q><N><E><Q><L><R><S><R><S><G><A><V><Q><G><A><G><S><L><G><P><G><S><P><V><R><A><G><A><S><I><P><S><S><G><A><A><S><P><R><G><F><P><L><G><L><S><A><K><S><G><G><G><P><G><S><G><P><R><R><T><S><S><E><E><L><R><D><A><T><S><L><L><A><A><G><E><G><G><L><L><D... | Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase.<BOP> | Q9P270 |
Q99929 | ASCL2_HUMAN | Mash2 | Homo | <M><D><G><G><T><L><P><R><S><A><P><P><A><P><P><V><P><V><G><C><A><A><R><R><R><P><A><S><P><E><L><L><R><C><S><R><R><R><R><P><A><T><A><E><T><G><G><G><A><A><A><V><A><R><R><N><E><R><E><R><N><R><V><K><L><V><N><L><G><F><Q><A><L><R><Q><H><V><P><H><G><G><A><S><K><K><L><S><K><V><E><T><L><R><S><A><V><E><Y><I><R><A><L><Q><R><L><L><A... | AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.<BOP> | Q99929 |
Q0VDF9 | HSP7E_HUMAN | Heat shock protein HSP60 | Homo | <M><A><A><I><G><V><H><L><G><C><T><S><A><C><V><A><V><Y><K><D><G><R><A><G><V><V><A><N><D><A><G><D><R><V><T><P><A><V><V><A><Y><S><E><N><E><E><I><V><G><L><A><A><K><Q><S><R><I><R><N><I><S><N><T><V><M><K><V><K><Q><I><L><G><R><S><S><S><D><P><Q><A><Q><K><Y><I><A><E><S><K><C><L><V><I><E><K><N><G><K><L><R><Y><E><I><D><T><G><E><E... | Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.<BOP> | Q0VDF9 |
Q8NH48 | OR5B3_HUMAN | Olfactory receptor OR11-239 | Homo | <M><E><N><K><T><E><V><T><Q><F><I><L><L><G><L><T><N><D><S><E><L><Q><V><P><L><F><I><T><F><P><F><I><Y><I><I><T><L><V><G><N><L><G><I><I><V><L><I><F><W><D><S><C><L><H><N><P><M><Y><F><F><L><S><N><L><S><L><V><D><F><C><Y><S><S><A><V><T><P><I><V><M><A><G><F><L><I><E><D><K><V><I><S><Y><N><A><C><A><A><Q><M><Y><I><F><V><A><F><A><T... | Odorant receptor.<BOP> | Q8NH48 |
A0A0J9YX75 | TVB69_HUMAN | T cell receptor beta variable 6-9 | Homo | <M><S><I><G><L><L><C><C><V><A><F><S><L><L><W><A><G><P><V><N><A><G><V><T><Q><T><P><K><F><H><I><L><K><T><G><Q><S><M><T><L><Q><C><A><Q><D><M><N><H><G><Y><L><S><W><Y><R><Q><D><P><G><M><G><L><R><R><I><H><Y><S><V><A><A><G><I><T><D><K><G><E><V><P><D><G><Y><N><V><S><R><S><N><T><E><D><F><P><L><R><L><E><S><A><A><P><S><Q><T><S><V... | V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (p... | A0A0J9YX75 |
Q502X0 | MORN2_HUMAN | MORN motif protein in testis | Homo | <M><N><G><F><G><R><L><E><H><F><S><G><A><V><Y><E><G><Q><F><K><D><N><M><F><H><G><L><G><T><Y><T><F><P><N><G><A><K><Y><T><G><N><F><N><E><N><R><V><E><G><E><G><E><Y><T><D><I><Q><G><L><E><W><S><G><N><F><H><F><T><A><A><P><D><L><K><L><K><L><H><M> | Might have a role in spermatogenesis.<BOP> | Q502X0 |
Q5GJ75 | TP8L3_HUMAN | Tumor necrosis factor alpha-induced protein 8-like protein 3 | Homo | <M><G><K><P><R><Q><N><P><S><T><L><V><S><T><L><C><E><A><E><P><K><G><K><L><W><V><N><G><Y><A><G><T><Q><G><T><R><D><A><T><L><Q><T><R><L><I><P><L><S><F><H><L><Q><R><G><K><G><L><A><A><P><L><S><A><L><S><A><P><R><L><P><E><R><P><A><D><G><R><V><A><V><D><A><Q><P><A><A><R><S><M><D><S><D><S><G><E><Q><S><E><G><E><P><V><T><A><A><G><P... | Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the ac... | Q5GJ75 |
Q00325 | MPCP_HUMAN | Solute carrier family 25 member 3 | Homo | <M><F><S><S><V><A><H><L><A><R><A><N><P><F><N><T><P><H><L><Q><L><V><H><D><G><L><G><D><L><R><S><S><S><P><G><P><T><G><Q><P><R><R><P><R><N><L><A><A><A><A><V><E><E><Q><Y><S><C><D><Y><G><S><G><R><F><F><I><L><C><G><L><G><G><I><I><S><C><G><T><T><H><T><A><L><V><P><L><D><L><V><K><C><R><M><Q><V><D><P><Q><K><Y><K><G><I><F><N><G><F... | Transport of phosphate groups from the cytosol to the mitochondrial matrix. Phosphate is cotransported with H(+). May play a role regulation of the mitochondrial permeability transition pore (mPTP).<BOP> | Q00325 |
A6NNF4 | ZN726_HUMAN | Zinc finger protein 726 | Homo | <M><G><L><L><T><F><R><D><V><A><I><E><F><S><L><E><E><W><Q><C><L><D><T><A><Q><K><N><L><Y><R><N><V><M><L><E><N><Y><R><N><L><A><F><L><G><I><A><V><S><K><P><D><L><I><I><C><L><E><K><E><K><E><P><W><N><M><K><R><D><E><M><V><D><E><P><P><G><I><C><P><H><F><A><Q><D><I><W><P><E><Q><G><V><E><D><S><F><Q><K><V><I><L><R><R><F><E><K><C><G... | May be involved in transcriptional regulation.<BOP> | A6NNF4 |
O60774 | FMO6_HUMAN | Flavin-containing monooxygenase 6 | Homo | <M><S><K><R><V><G><I><I><G><A><G><V><S><G><L><A><A><I><W><C><C><L><E><E><G><L><E><P><T><C><F><E><R><S><D><D><V><G><G><L><W><K><F><S><D><H><T><E><E><G><R><A><S><I><Y><Q><S><V><F><T><N><S><S><K><E><M><M><C><F><P><D><F><P><Y><P><D><D><Y><P><N><Y><I><H><H><S><K><L><Q><E><Y><I><K><T><Y><A><Q><K><K><D><L><L><R><Y><I><Q><F><E... | It is probable that this protein is only produced in very small quantity or not at all as the gene coding for it seems to be unable to produce full-length transcripts.<BOP> | O60774 |
Q8IW45 | NNRD_HUMAN | NAD(P)HX dehydratase | Homo | <M><V><T><R><A><G><A><G><T><A><V><A><G><A><V><V><V><A><L><L><S><A><A><L><A><L><Y><G><P><P><L><D><A><V><L><E><R><A><F><S><L><R><K><A><H><S><I><K><D><M><E><N><T><L><Q><L><V><R><N><I><I><P><P><L><S><S><T><K><H><K><G><Q><D><G><R><I><G><V><V><G><G><C><Q><E><Y><T><G><A><P><Y><F><A><A><I><S><A><L><K><V><G><A><D><L><S><H><V><F... | Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-depen... | Q8IW45 |
A6NKX4 | S22AV_HUMAN | Putative solute carrier family 22 member 31 | Homo | <M><E><Q><E><A><R><V><L><R><A><A><G><G><F><G><R><A><R><R><L><L><A><S><A><S><W><V><P><C><I><V><L><G><L><V><L><S><S><E><E><L><L><T><A><Q><P><A><P><H><C><R><P><D><P><T><L><L><P><P><A><L><R><A><L><R><G><P><A><L><L><D><A><A><I><P><R><L><G><P><T><R><A><P><A><E><A><L><G><V><L><S><P><S><Y><L><A><P><L><T><R><A><P><R><P><S><S><W... | Organic anion transporter that mediates the uptake of ions.<BOP> | A6NKX4 |
Q13425 | SNTB2_HUMAN | Syntrophin-like | Homo | <M><R><V><A><A><A><T><A><A><A><G><A><G><P><A><M><A><V><W><T><R><A><T><K><A><G><L><V><E><L><L><L><R><E><R><W><V><R><V><V><A><E><L><S><G><E><S><L><S><L><T><G><D><A><A><A><A><E><L><E><P><A><L><G><P><A><A><A><A><F><N><G><L><P><N><G><G><G><A><G><D><S><L><P><G><S><P><S><R><G><L><G><P><P><S><P><P><A><P><P><R><G><P><A><G><E><A... | Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.<BOP> | Q13425 |
Q8N4P2 | TT30B_HUMAN | Tetratricopeptide repeat protein 30B | Homo | <M><A><G><L><S><G><A><Q><I><P><D><G><E><F><T><A><V><V><Y><R><L><I><R><N><A><R><Y><A><E><A><V><Q><L><L><G><G><E><L><Q><R><S><P><R><S><R><A><G><L><S><L><L><G><Y><C><Y><Y><R><L><Q><E><F><A><L><A><A><E><C><Y><E><Q><L><G><Q><L><H><P><E><L><E><Q><Y><R><L><Y><Q><A><Q><A><L><Y><K><A><C><L><Y><A><E><A><T><R><V><A><F><L><L><L><D... | Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.<BOP> | Q8N4P2 |
Q8N187 | CARTF_HUMAN | Testis development protein NYD-SP24 | Homo | <M><E><Q><S><N><D><S><L><R><V><N><H><N><D><G><E><E><S><K><T><S><A><Q><V><F><E><H><L><I><C><M><D><S><R><D><S><S><F><G><Q><N><D><S><P><T><V><L><P><I><T><T><R><E><A><N><N><S><L><I><S><Q><N><I><P><G><P><L><T><Q><T><Q><T><L><S><A><E><Q><F><H><L><V><D><Q><N><G><Q><A><I><Q><Y><E><L><Q><S><L><G><E><S><N><A><Q><M><M><I><V><A><S... | Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.<BOP> | Q8N187 |
P23677 | IP3KA_HUMAN | Inositol 1,4,5-trisphosphate 3-kinase A | Homo | <M><T><L><P><G><G><P><T><G><M><A><R><P><G><G><A><R><P><C><S><P><G><L><E><R><A><P><R><R><S><V><G><E><L><R><L><L><F><E><A><R><C><A><A><V><A><A><A><A><A><A><G><E><P><R><A><R><G><A><K><R><R><G><G><Q><V><P><N><G><L><P><R><A><P><P><A><P><V><I><P><Q><L><T><V><T><A><E><E><P><D><V><P><P><T><S><P><G><P><P><E><R><E><R><D><C><L><P... | Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis.<BOP> | P23677 |
C9JN71 | ZN878_HUMAN | Zinc finger protein 878 | Homo | <M><D><S><V><A><F><E><D><V><A><V><N><F><T><Q><E><E><W><A><L><L><D><P><S><Q><K><N><L><Y><R><E><V><M><Q><E><T><L><R><N><L><T><S><I><G><K><K><W><N><N><Q><Y><I><E><D><E><H><Q><N><P><R><R><N><L><R><R><L><I><G><E><R><L><S><E><S><K><E><S><H><Q><H><G><E><V><L><T><Q><V><P><D><D><T><L><K><K><K><T><P><G><V><Q><S><Y><E><S><S><V><C... | May be involved in transcriptional regulation.<BOP> | C9JN71 |
Q969G2 | LHX4_HUMAN | LIM/homeobox protein Lhx4 | Homo | <M><M><Q><S><A><T><V><P><A><E><G><A><V><K><G><L><P><E><M><L><G><V><P><M><Q><Q><I><P><Q><C><A><G><C><N><Q><H><I><L><D><K><F><I><L><K><V><L><D><R><H><W><H><S><S><C><L><K><C><A><D><C><Q><M><Q><L><A><D><R><C><F><S><R><A><G><S><V><Y><C><K><E><D><F><F><K><R><F><G><T><K><C><T><A><C><Q><Q><G><I><P><P><T><Q><V><V><R><K><A><Q><D... | May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA .<BOP> | Q969G2 |
A0A087WXM9 | MEIKN_HUMAN | Meiosis-specific kinetochore protein | Homo | <M><W><P><L><R><V><Y><T><R><K><K><R><E><G><Q><R><L><N><L><T><P><T><P><D><L><G><S><P><A><K><A><E><A><P><P><G><S><K><R><K><G><K><V><H><G><L><S><K><I><A><E><K><A><E><R><S><R><Q><G><G><S><G><S><G><P><F><S><P><R><L><G><V><T><G><E><K><S><L><Q><E><N><R><S><S><E><D><T><Q><D><E><K><I><A><S><L><R><E><S><V><T><D><D><L><Q><V><D><S... | Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the sam... | A0A087WXM9 |
O14770 | MEIS2_HUMAN | Meis1-related protein 1 | Homo | <M><A><Q><R><Y><D><E><L><P><H><Y><G><G><M><D><G><V><G><V><P><A><S><M><Y><G><D><P><H><A><P><R><P><I><P><P><V><H><H><L><N><H><G><P><P><L><H><A><T><Q><H><Y><G><A><H><A><P><H><P><N><V><M><P><A><S><M><G><S><A><V><N><D><A><L><K><R><D><K><D><A><I><Y><G><H><P><L><F><P><L><L><A><L><V><F><E><K><C><E><L><A><T><C><T><P><R><E><P><G... | Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in t... | O14770 |
P0DOX4 | IGE_HUMAN | Immunoglobulin epsilon heavy chain ND | Homo | <Q><V><Q><L><V><Q><S><G><A><E><V><R><K><P><G><A><S><V><R><V><S><C><K><A><S><G><Y><T><F><I><D><S><Y><V><G><W><I><R><Q><A><P><G><H><G><L><E><W><I><H><W><I><N><P><N><S><G><G><T><N><Y><A><P><R><F><Q><G><R><V><T><M><T><R><D><A><S><F><S><T><A><Y><M><D><L><R><S><L><R><S><D><D><S><A><V><F><Y><C><A><K><S><D><P><F><W><S><D><Y><N... | Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocy... | P0DOX4 |
P49585 | PCY1A_HUMAN | Phosphorylcholine transferase A | Homo | <M><D><A><Q><C><S><A><K><V><N><A><R><K><R><R><K><E><A><P><G><P><N><G><A><T><E><E><D><G><V><P><S><K><V><Q><R><C><A><V><G><L><R><Q><P><A><P><F><S><D><E><I><E><V><D><F><S><K><P><Y><V><R><V><T><M><E><E><A><S><R><G><T><P><C><E><R><P><V><R><V><Y><A><D><G><I><F><D><L><F><H><S><G><H><A><R><A><L><M><Q><A><K><N><L><F><P><N><T><Y... | Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.<BOP> | P49585 |
Q9UHK0 | NUFP1_HUMAN | Nuclear FMRP-interacting protein 1 | Homo | <M><A><E><P><T><S><D><F><E><T><P><I><G><W><H><A><S><P><E><L><T><P><T><L><G><P><L><S><D><T><A><P><P><R><D><S><W><M><F><W><A><M><L><P><P><P><P><P><P><L><T><S><S><L><P><A><A><G><S><K><P><S><S><E><S><Q><P><P><M><E><A><Q><S><L><P><G><A><P><P><P><F><D><A><Q><I><L><P><G><A><Q><P><P><F><D><A><Q><S><P><L><D><S><Q><P><Q><P><S><G... | Binds RNA.<BOP> | Q9UHK0 |
Q9NP95 | FGF20_HUMAN | Fibroblast growth factor 20 | Homo | <M><A><P><L><A><E><V><G><G><F><L><G><G><L><E><G><L><G><Q><Q><V><G><S><H><F><L><L><P><P><A><G><E><R><P><P><L><L><G><E><R><R><S><A><A><E><R><S><A><R><G><G><P><G><A><A><Q><L><A><H><L><H><G><I><L><R><R><R><Q><L><Y><C><R><T><G><F><H><L><Q><I><L><P><D><G><S><V><Q><G><T><R><Q><D><H><S><L><F><G><I><L><E><F><I><S><V><A><V><G><L... | Neurotrophic factor that regulates central nervous development and function.<BOP> | Q9NP95 |
Q9UHQ9 | NB5R1_HUMAN | NAD(P)H:quinone oxidoreductase type 3 polypeptide A2 | Homo | <M><G><I><Q><T><S><P><V><L><L><A><S><L><G><V><G><L><V><T><L><L><G><L><A><V><G><S><Y><L><V><R><R><S><R><R><P><Q><V><T><L><L><D><P><N><E><K><Y><L><L><R><L><L><D><K><T><T><V><S><H><N><T><K><R><F><R><F><A><L><P><T><A><H><H><T><L><G><L><P><V><G><K><H><I><Y><L><S><T><R><I><D><G><S><L><V><I><R><P><Y><T><P><V><T><S><D><E><D><Q... | NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.<BOP> | Q9UHQ9 |
P17987 | TCPA_HUMAN | CCT-alpha | Homo | <M><E><G><P><L><S><V><F><G><D><R><S><T><G><E><T><I><R><S><Q><N><V><M><A><A><A><S><I><A><N><I><V><K><S><S><L><G><P><V><G><L><D><K><M><L><V><D><D><I><G><D><V><T><I><T><N><D><G><A><T><I><L><K><L><L><E><V><E><H><P><A><A><K><V><L><C><E><L><A><D><L><Q><D><K><E><V><G><D><G><T><T><S><V><V><I><I><A><A><E><L><L><K><N><A><D><E><L... | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis . The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance . As part of the TRiC complex may play a role in the assembly of BBSome, a comp... | P17987 |
P60370 | KR105_HUMAN | Keratin-associated protein 18.5 | Homo | <M><A><A><C><T><M><S><V><C><S><S><A><C><S><D><S><W><R><V><D><D><C><P><E><S><C><C><E><P><P><C><G><T><A><P><C><L><T><L><V><C><T><P><V><S><C><V><S><S><P><C><C><Q><A><A><C><E><P><S><P><C><Q><S><G><C><T><S><S><C><T><P><S><C><C><Q><P><A><C><C><A><S><S><P><C><Q><Q><A><C><C><V><P><V><C><C><K><P><V><C><C><L><P><T><C><S><K><D><S... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60370 |
Q16585 | SGCB_HUMAN | A3b | Homo | <M><A><A><A><A><A><A><A><A><E><Q><Q><S><S><N><G><P><V><K><K><S><M><R><E><K><A><V><E><R><R><S><V><N><K><E><H><N><S><N><F><K><A><G><Y><I><P><I><D><E><D><R><L><H><K><T><G><L><R><G><R><K><G><N><L><A><I><C><V><I><I><L><L><F><I><L><A><V><I><N><L><I><I><T><L><V><I><W><A><V><I><R><I><G><P><N><G><C><D><S><M><E><F><H><E><S><G><L... | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.<BOP> | Q16585 |
O60669 | MOT2_HUMAN | Solute carrier family 16 member 7 | Homo | <M><P><P><M><P><S><A><P><P><V><H><P><P><P><D><G><G><W><G><W><I><V><V><G><A><A><F><I><S><I><G><F><S><Y><A><F><P><K><A><V><T><V><F><F><K><E><I><Q><Q><I><F><H><T><T><Y><S><E><I><A><W><I><S><S><I><M><L><A><V><M><Y><A><G><G><P><V><S><S><V><L><V><N><K><Y><G><S><R><P><V><V><I><A><G><G><L><L><C><C><L><G><M><V><L><A><S><F><S><S... | Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate . Dimerization is functionally required and both subunits work cooperatively in transporting substrate .<BO... | O60669 |
Q05952 | STP2_HUMAN | Nuclear transition protein 2 | Homo | <M><D><T><Q><T><H><S><L><P><I><T><H><T><Q><L><H><S><N><S><Q><P><Q><S><R><T><C><T><R><H><C><Q><T><F><S><Q><S><C><R><Q><S><H><R><G><S><R><S><Q><S><S><S><Q><S><P><A><S><H><R><N><P><T><G><A><H><S><S><S><G><H><Q><S><Q><S><P><N><T><S><P><P><P><K><R><H><K><K><T><M><N><S><H><H><S><P><M><R><P><T><I><L><H><C><R><C><P><K><N><R><K... | Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.<BOP> | Q05952 |
Q9H3H1 | MOD5_HUMAN | tRNA isopentenyltransferase 1 | Homo | <M><A><S><V><A><A><A><R><A><V><P><V><G><S><G><L><R><G><L><Q><R><T><L><P><L><V><V><I><L><G><A><T><G><T><G><K><S><T><L><A><L><Q><L><G><Q><R><L><G><G><E><I><V><S><A><D><S><M><Q><V><Y><E><G><L><D><I><I><T><N><K><V><S><A><Q><E><Q><R><I><C><R><H><H><M><I><S><F><V><D><P><L><V><T><N><Y><T><V><V><D><F><R><N><R><A><T><A><L><I><E... | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37) . Mediates modification of a limited subset of tRNAs: tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification... | Q9H3H1 |
Q8TAC9 | SCAM5_HUMAN | Secretory carrier-associated membrane protein 5 | Homo | <M><A><E><K><V><N><N><F><P><P><L><P><K><F><I><P><L><K><P><C><F><Y><Q><D><F><E><A><D><I><P><P><Q><H><V><S><M><T><K><R><L><Y><Y><L><W><M><L><N><S><V><T><L><A><V><N><L><V><G><C><L><A><W><L><I><G><G><G><G><A><T><N><F><G><L><A><F><L><W><L><I><L><F><T><P><C><S><Y><V><C><W><F><R><P><I><Y><K><A><F><K><T><D><S><S><F><S><F><M><A... | Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis path... | Q8TAC9 |
Q8NHQ9 | DDX55_HUMAN | DEAD box protein 55 | Homo | <M><E><H><V><T><E><G><S><W><E><S><L><P><V><P><L><H><P><Q><V><L><G><A><L><R><E><L><G><F><P><Y><M><T><P><V><Q><S><A><T><I><P><L><F><M><R><N><K><D><V><A><A><E><A><V><T><G><S><G><K><T><L><A><F><V><I><P><I><L><E><I><L><L><R><R><E><E><K><L><K><K><S><Q><V><G><A><I><I><I><T><P><T><R><E><L><A><I><Q><I><D><E><V><L><S><H><F><T><K... | Probable ATP-binding RNA helicase.<BOP> | Q8NHQ9 |
Q9H1B4 | NXF5_HUMAN | TAP-like protein 1 | Homo | <M><R><R><N><T><Q><D><E><N><M><R><K><W><F><K><V><T><I><P><Y><G><I><K><Y><D><K><A><W><L><M><N><S><I><Q><S><N><C><S><V><P><F><T><P><V><D><F><H><Y><I><R><N><R><A><C><F><F><V><Q><V><A><S><A><A><S><A><L><K><D><V><S><Y><K><I><Y><D><D><E><N><Q><K><I><C><I><F><V><S><H><F><T><A><P><Y><S><V><K><N><K><L><K><P><G><Q><M><E><M><L><K... | Could be involved in the export of mRNA from the nucleus to the cytoplasm. Could also have a role in polarized cytoplasmic transport and localization of mRNA in neurons.<BOP> | Q9H1B4 |
Q9H1Y0 | ATG5_HUMAN | Apoptosis-specific protein | Homo | <M><T><D><D><K><D><V><L><R><D><V><W><F><G><R><I><P><T><C><F><T><L><Y><Q><D><E><I><T><E><R><E><A><E><P><Y><Y><L><L><L><P><R><V><S><Y><L><T><L><V><T><D><K><V><K><K><H><F><Q><K><V><M><R><Q><E><D><I><S><E><I><W><F><E><Y><E><G><T><P><L><K><W><H><Y><P><I><G><L><L><F><D><L><L><A><S><S><S><A><L><P><W><N><I><T><V><H><F><K><S><F... | (Microbial infection) May act as a proviral factor. In association with ATG12, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection . Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for... | Q9H1Y0 |
Q8N9N2 | ASCC1_HUMAN | Trip4 complex subunit p50 | Homo | <M><E><V><L><R><P><Q><L><I><R><I><D><G><R><N><Y><R><K><N><P><V><Q><E><Q><T><Y><Q><H><E><E><D><E><E><D><F><Y><Q><G><S><M><E><C><A><D><E><P><C><D><A><Y><E><V><E><Q><T><P><Q><G><F><R><S><T><L><R><A><P><S><L><L><Y><N><L><I><H><L><N><T><S><N><D><C><G><F><Q><K><I><T><L><D><C><Q><N><I><Y><T><W><K><S><R><H><I><V><G><K><R><G><D... | Plays a role in DNA damage repair as component of the ASCC complex . Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation . In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of... | Q8N9N2 |
Q14137 | BOP1_HUMAN | Block of proliferation 1 protein | Homo | <M><A><G><S><R><G><A><G><R><T><A><A><P><S><V><R><P><E><K><R><R><S><E><P><E><L><E><P><E><P><E><P><E><P><P><L><L><C><T><S><P><L><S><H><S><T><G><S><D><S><G><V><S><D><S><E><E><S><V><F><S><G><L><E><D><S><G><S><D><S><S><E><D><D><D><E><G><D><E><E><G><E><D><G><A><L><D><D><E><G><H><S><G><I><K><K><T><T><E><E><Q><V><Q><A><S><T><P... | Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.<BOP> | Q14137 |
P52954 | LBX1_HUMAN | Ladybird homeobox protein homolog 1 | Homo | <M><T><S><K><E><D><G><K><A><A><P><G><E><E><R><R><R><S><P><L><D><H><L><P><P><P><A><N><S><N><K><P><L><T><P><F><S><I><E><D><I><L><N><K><P><S><V><R><R><S><Y><S><L><C><G><A><A><H><L><L><A><A><A><D><K><H><A><Q><G><G><L><P><L><A><G><R><A><L><L><S><Q><T><S><P><L><C><A><L><E><E><L><A><S><K><T><F><K><G><L><E><V><S><V><L><Q><A><A... | Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.<BOP> | P52954 |
A0A075B6Y9 | TJA42_HUMAN | T cell receptor alpha joining 42 | Homo | <Y><G><G><S><Q><G><N><L><I><F><G><K><G><T><K><L><S><V><K><P> | J region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A075B6Y9 |
P55899 | FCGRN_HUMAN | Neonatal Fc receptor | Homo | <M><G><V><P><R><P><Q><P><W><A><L><G><L><L><L><F><L><L><P><G><S><L><G><A><E><S><H><L><S><L><L><Y><H><L><T><A><V><S><S><P><A><P><G><T><P><A><F><W><V><S><G><W><L><G><P><Q><Q><Y><L><S><Y><N><S><L><R><G><E><A><E><P><C><G><A><W><V><W><E><N><Q><V><S><W><Y><W><E><K><E><T><T><D><L><R><I><K><E><K><L><F><L><E><A><F><K><A><L><G><G... | (Microbial infection) Acts as an uncoating receptor for a panel of echoviruses including Echovirus 5, 6, 7, 9, 11, 13, 25 and 29.<BOP> | P55899 |
Q9NRG4 | SMYD2_HUMAN | SET and MYND domain-containing protein 2 | Homo | <M><R><A><E><G><L><G><G><L><E><R><F><C><S><P><G><K><G><R><G><L><R><A><L><Q><P><F><Q><V><G><D><L><L><F><S><C><P><A><Y><A><Y><V><L><T><V><N><E><R><G><N><H><C><E><Y><C><F><T><R><K><E><G><L><S><K><C><G><R><C><K><Q><A><F><Y><C><N><V><E><C><Q><K><E><D><W><P><M><H><K><L><E><C><S><P><M><V><V><F><G><E><N><W><N><P><S><E><T><V><R... | Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of... | Q9NRG4 |
Q8N5S1 | S2541_HUMAN | Solute carrier family 25 member 41 | Homo | <M><G><A><Q><P><G><E><P><Q><N><T><C><S><R><I><Q><T><L><F><R><R><V><K><T><L><L><I><K><A><P><P><P><P><Q><P><P><P><P><P><P><S><W><N><P><G><C><T><H><V><Y><G><Y><A><F><G><H><M><H><D><N><N><L><E><H><L><P><S><Q><Q><V><L><D><T><G><E><Q><L><M><V><P><V><E><V><L><E><V><D><N><K><E><A><L><W><K><F><L><L><S><G><A><M><A><G><A><V><S><R... | Calcium-independent ATP-Mg/Pi exchanger that catalyzes the electroneutral exchange of Mg-ATP or free ADP against an hydrogenphosphate and participates in the net transport of adenine nucleotides across the mitochondria inner membrane.<BOP> | Q8N5S1 |
Q9NWS1 | PARI_HUMAN | PARP1-binding protein | Homo | <M><A><V><F><N><Q><K><S><V><S><D><M><I><K><E><F><R><K><N><W><R><A><L><C><N><S><E><R><T><T><L><C><G><A><D><S><M><L><L><A><L><Q><L><S><M><A><E><N><N><K><Q><H><S><G><E><F><T><V><S><L><S><D><V><L><L><T><W><K><Y><L><L><H><E><K><L><N><L><P><V><E><N><M><D><V><T><D><H><Y><E><D><V><R><K><I><Y><D><D><F><L><K><N><S><N><M><L><D><L... | Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers... | Q9NWS1 |
O95007 | OR6B1_HUMAN | Olfactory receptor OR7-9 | Homo | <M><E><L><E><N><Q><T><R><V><T><K><F><I><L><V><G><F><P><G><S><L><S><M><R><A><A><M><F><L><I><F><L><V><A><Y><I><L><T><V><A><E><N><V><I><I><I><L><L><V><L><Q><N><R><P><L><H><K><P><M><Y><F><F><L><A><N><L><S><F><L><E><T><W><Y><I><S><V><T><V><P><K><L><L><F><S><F><W><S><V><N><N><S><I><S><F><T><L><C><M><I><Q><L><Y><F><F><I><A><L... | Odorant receptor.<BOP> | O95007 |
Q9GZT4 | SRR_HUMAN | L-serine dehydratase | Homo | <M><C><A><Q><Y><C><I><S><F><A><D><V><E><K><A><H><I><N><I><R><D><S><I><H><L><T><P><V><L><T><S><S><I><L><N><Q><L><T><G><R><N><L><F><F><K><C><E><L><F><Q><K><T><G><S><F><K><I><R><G><A><L><N><A><V><R><S><L><V><P><D><A><L><E><R><K><P><K><A><V><V><T><H><S><S><G><N><H><G><Q><A><L><T><Y><A><A><K><L><E><G><I><P><A><Y><I><V><V><P... | Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.<BOP> | Q9GZT4 |
P22830 | HEMH_HUMAN | Protoheme ferro-lyase | Homo | <M><R><S><L><G><A><N><M><A><A><A><L><R><A><A><G><V><L><L><R><D><P><L><A><S><S><S><W><R><V><C><Q><P><W><R><W><K><S><G><A><A><A><A><A><V><T><T><E><T><A><Q><H><A><Q><G><A><K><P><Q><V><Q><P><Q><K><R><K><P><K><T><G><I><L><M><L><N><M><G><G><P><E><T><L><G><D><V><H><D><F><L><L><R><L><F><L><D><R><D><L><M><T><L><P><I><Q><N><K><L... | Catalyzes the ferrous insertion into protoporphyrin IX.<BOP> | P22830 |
Q6PI73 | LIRA6_HUMAN | Leukocyte Ig-like receptor | Homo | <M><T><P><A><L><T><A><L><L><C><L><G><L><S><L><G><P><R><T><R><V><Q><A><G><P><F><P><K><P><T><L><W><A><E><P><G><S><V><I><S><W><G><S><P><V><T><I><W><C><Q><G><S><L><E><A><Q><E><Y><Q><L><D><K><E><G><S><P><E><P><L><D><R><N><N><P><L><E><P><K><N><K><A><R><F><S><I><P><S><M><T><Q><H><H><A><G><R><Y><R><C><H><Y><Y><S><S><A><G><W><S... | May act as receptor for class I MHC antigens.<BOP> | Q6PI73 |
O75419 | CDC45_HUMAN | PORC-PI-1 | Homo | <M><F><V><S><D><F><R><K><E><F><Y><E><V><V><Q><S><Q><R><V><L><L><F><V><A><S><D><V><D><A><L><C><A><C><K><I><L><Q><A><L><F><Q><C><D><H><V><Q><Y><T><L><V><P><V><S><G><W><Q><E><L><E><T><A><F><L><E><H><K><E><Q><F><H><Y><F><I><L><I><N><C><G><A><N><V><D><L><L><D><I><L><Q><P><D><E><D><T><I><F><F><V><C><D><T><H><R><P><V><N><V><V... | Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.<BOP> | O75419 |
A6NJB7 | PRR19_HUMAN | Proline-rich protein 19 | Homo | <M><D><T><Q><G><P><V><S><Q><P><F><Q><Q><P><E><K><P><G><R><V><R><R><R><K><T><R><R><E><R><N><K><A><L><V><G><S><R><R><P><L><A><H><H><D><P><P><V><A><I><R><D><P><P><V><V><P><T><A><S><K><L><V><V><I><T><Q><G><R><L><S><R><E><H><R><G><L><F><N><H><E><V><K><S><L><D><V><A><R><L><L><S><S><G><T><L><V><P><G><S><P><T><L><P><A><K><P><S... | Promotes meiotic crossing over formation through its interaction with CNTD1 by participating in the crossover differentiation step of crossover-specific recombination intermediates.<BOP> | A6NJB7 |
O95396 | MOCS3_HUMAN | Sulfurtransferase MOCS3 | Homo | <M><A><S><R><E><E><V><L><A><L><Q><A><E><V><A><Q><R><E><E><E><L><N><S><L><K><Q><K><L><A><S><A><L><L><A><E><Q><E><P><Q><P><E><R><L><V><P><V><S><P><L><P><P><K><A><A><L><S><R><D><E><I><L><R><Y><S><R><Q><L><V><L><P><E><L><G><V><H><G><Q><L><R><L><G><T><A><C><V><L><I><V><G><C><G><G><L><G><C><P><L><A><Q><Y><L><A><A><A><G><V><G... | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS... | O95396 |
Q8N687 | DB125_HUMAN | Defensin, beta 125 | Homo | <M><N><I><L><M><L><T><F><I><I><C><G><L><L><T><R><V><T><K><G><S><F><E><P><Q><K><C><W><K><N><N><V><G><H><C><R><R><R><C><L><D><T><E><R><Y><I><L><L><C><R><N><K><L><S><C><C><I><S><I><I><S><H><E><Y><T><R><R><P><A><F><P><V><I><H><L><E><D><I><T><L><D><Y><S><D><V><D><S><F><T><G><S><P><V><S><M><L><N><D><L><I><T><F><D><T><T><K><F... | Has antibacterial activity.<BOP> | Q8N687 |
Q92535 | PIGC_HUMAN | Phosphatidylinositol-glycan biosynthesis class C protein | Homo | <M><Y><A><Q><P><V><T><N><T><K><E><V><K><W><Q><K><V><L><Y><E><R><Q><P><F><P><D><N><Y><V><D><R><R><F><L><E><E><L><R><K><N><I><H><A><R><K><Y><Q><Y><W><A><V><V><F><E><S><S><V><V><I><Q><Q><L><C><S><V><C><V><F><V><V><I><W><W><Y><M><D><E><G><L><L><A><P><H><W><L><L><G><T><G><L><A><S><S><L><I><G><Y><V><L><F><D><L><I><D><G><G><E... | Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.<BOP> | Q92535 |
P55344 | LMIP_HUMAN | MP20 | Homo | <M><Y><S><F><M><G><G><G><L><F><C><A><W><V><G><T><I><L><L><V><V><A><M><A><T><D><H><W><M><Q><Y><R><L><S><G><S><F><A><H><Q><G><L><W><R><Y><C><L><G><N><K><C><Y><L><Q><T><D><S><I><A><Y><W><N><A><T><R><A><F><M><I><L><S><A><L><C><A><I><S><G><I><I><M><G><I><M><A><F><A><H><Q><P><T><F><S><R><I><S><R><P><F><S><A><G><I><M><F><F><S... | Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.<BOP> | P55344 |
Q13875 | MOBP_HUMAN | Myelin-associated oligodendrocyte basic protein | Homo | <M><S><Q><K><P><A><K><E><G><P><R><L><S><K><N><Q><K><Y><S><E><H><F><S><I><H><C><C><P><P><F><T><F><L><N><S><K><K><E><I><V><D><R><K><Y><S><I><C><K><S><G><C><F><Y><Q><K><K><E><E><D><W><I><C><C><A><C><Q><K><T><R><T><S><R><R><A><K><S><P><Q><R><P><K><Q><Q><P><A><A><P><P><A><V><V><R><A><P><A><K><P><R><S><P><P><R><S><E><R><Q><P... | May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.<BOP> | Q13875 |
O15198 | SMAD9_HUMAN | SMAD family member 9 | Homo | <M><H><S><T><T><P><I><S><S><L><F><S><F><T><S><P><A><V><K><R><L><L><G><W><K><Q><G><D><E><E><E><K><W><A><E><K><A><V><D><S><L><V><K><K><L><K><K><K><K><G><A><M><D><E><L><E><R><A><L><S><C><P><G><Q><P><S><K><C><V><T><I><P><R><S><L><D><G><R><L><Q><V><S><H><R><K><G><L><P><H><V><I><Y><C><R><V><W><R><W><P><D><L><Q><S><H><H><E><L... | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).<BOP> | O15198 |
P05549 | AP2A_HUMAN | Activator protein 2 | Homo | <M><L><W><K><L><T><D><N><I><K><Y><E><D><C><E><D><R><H><D><G><T><S><N><G><T><A><R><L><P><Q><L><G><T><V><G><Q><S><P><Y><T><S><A><P><P><L><S><H><T><P><N><A><D><F><Q><P><P><Y><F><P><P><P><Y><Q><P><I><Y><P><Q><S><Q><D><P><Y><S><H><V><N><D><P><Y><S><L><N><P><L><H><A><Q><P><Q><P><Q><H><P><G><W><P><G><Q><R><Q><S><Q><E><S><G><L... | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, ... | P05549 |
Q5H9I0 | TFDP3_HUMAN | Hepatocellular carcinoma-associated antigen 661 | Homo | <M><A><K><Y><V><S><L><T><E><A><N><E><E><L><K><V><L><M><D><E><N><Q><T><S><R><P><V><A><V><H><T><S><T><V><N><P><L><G><K><Q><L><L><P><K><T><F><G><Q><S><S><V><N><I><D><Q><Q><V><V><I><G><M><P><Q><R><P><A><A><S><N><I><P><V><V><G><S><P><N><P><P><S><T><H><F><A><S><Q><N><Q><H><S><Y><S><S><P><P><W><A><G><Q><H><N><R><K><G><E><K><N... | Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.<BOP> | Q5H9I0 |
O00566 | MPP10_HUMAN | M phase phosphoprotein 10 | Homo | <M><A><P><Q><V><W><R><R><R><T><L><E><R><C><L><T><E><V><G><K><A><T><G><R><P><E><C><F><L><T><I><Q><E><G><L><A><S><K><F><T><S><L><T><K><V><L><Y><D><F><N><K><I><L><E><N><G><R><I><H><G><S><P><L><Q><K><L><V><I><E><N><F><D><D><E><Q><I><W><Q><Q><L><E><L><Q><N><E><P><I><L><Q><Y><F><Q><N><A><V><S><E><T><I><N><D><E><D><I><S><L><L... | Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.<BOP> | O00566 |
Q6NXT2 | H3C_HUMAN | Histone H3.5 | Homo | <M><A><R><T><K><Q><T><A><R><K><S><T><G><G><K><A><P><R><K><Q><L><A><T><K><A><A><R><K><S><T><P><S><T><C><G><V><K><P><H><R><Y><R><P><G><T><V><A><L><R><E><I><R><R><Y><Q><K><S><T><E><L><L><I><R><K><L><P><F><Q><R><L><V><R><E><I><A><Q><D><F><N><T><D><L><R><F><Q><S><A><A><V><G><A><L><Q><E><A><S><E><A><Y><L><V><G><L><L><E><D><T... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | Q6NXT2 |
P27695 | APEX1_HUMAN | DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial | Homo | <M><P><K><R><G><K><K><G><A><V><A><E><D><G><D><E><L><R><T><E><P><E><A><K><K><S><K><T><A><A><K><K><N><D><K><E><A><A><G><E><G><P><A><L><Y><E><D><P><P><D><Q><K><T><S><P><S><G><K><P><A><T><L><K><I><C><S><W><N><V><D><G><L><R><A><W><I><K><K><K><G><L><D><W><V><K><E><E><A><P><D><I><L><C><L><Q><E><T><K><C><S><E><N><K><L><P><A><E... | Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions i... | P27695 |
Q9H306 | MMP27_HUMAN | Matrix metalloproteinase-27 | Homo | <M><K><R><L><L><L><L><F><L><F><F><I><T><F><S><S><A><F><P><L><V><R><M><T><E><N><E><E><N><M><Q><L><A><Q><A><Y><L><N><Q><F><Y><S><L><E><I><E><G><N><H><L><V><Q><S><K><N><R><S><L><I><D><D><K><I><R><E><M><Q><A><F><F><G><L><T><V><T><G><K><L><D><S><N><T><L><E><I><M><K><T><P><R><C><G><V><P><D><V><G><Q><Y><G><Y><T><L><P><G><W><R... | Matrix metalloproteinases degrade protein components of the extracellular matrix such as fibronectin, laminin, gelatins and/or collagens.<BOP> | Q9H306 |
Q9H790 | EXO5_HUMAN | Defects in morphology protein 1 homolog | Homo | <M><A><E><T><R><E><E><E><T><V><S><A><E><A><S><G><F><S><D><L><S><D><S><E><F><L><E><F><L><D><L><E><D><A><Q><E><S><K><A><L><V><N><M><P><G><P><S><S><E><S><L><G><K><D><D><K><P><I><S><L><Q><N><W><K><R><G><L><D><I><L><S><P><M><E><R><F><H><L><K><Y><L><Y><V><T><D><L><A><T><Q><N><W><C><E><L><Q><T><A><Y><G><K><E><L><P><G><F><L><A... | Single-stranded DNA (ssDNA) bidirectional exonuclease involved in DNA repair. Probably involved in DNA repair following ultraviolet (UV) irradiation and interstrand cross-links (ICLs) damage. Has both 5'-3' and 3'-5' exonuclease activities with a strong preference for 5'-ends. Acts as a sliding exonuclease that loads a... | Q9H790 |
O60909 | B4GT2_HUMAN | UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2 | Homo | <M><S><R><L><L><G><G><T><L><E><R><V><C><K><A><V><L><L><L><C><L><L><H><F><L><V><A><V><I><L><Y><F><D><V><Y><A><Q><H><L><A><F><F><S><R><F><S><A><R><G><P><A><H><A><L><H><P><A><A><S><S><S><S><S><S><S><N><C><S><R><P><N><A><T><A><S><S><S><G><L><P><E><V><P><S><A><L><P><G><P><T><A><P><T><L><P><P><C><P><D><S><P><P><G><L><V><G><R... | Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids . Can produce lactose .<BOP> | O60909 |
A6NJ78 | MET15_HUMAN | Methyltransferase-like protein 15 | Homo | <M><L><R><Y><P><Y><F><C><R><M><Y><K><E><C><L><S><C><W><L><E><S><G><I><P><N><L><G><V><W><P><N><R><I><H><T><T><A><E><K><Y><R><E><Y><E><A><R><E><Q><T><D><Q><T><Q><A><Q><E><L><H><R><S><Q><D><R><D><F><E><T><M><A><K><L><H><I><P><V><M><V><D><E><V><V><H><C><L><S><P><Q><K><G><Q><I><F><L><D><M><T><F><G><S><G><G><H><T><K><A><I><L... | N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA . Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits .<BOP> | A6NJ78 |
Q5T013 | HYI_HUMAN | Endothelial cell apoptosis protein E-CE1 | Homo | <M><A><P><L><R><F><S><A><N><L><S><W><L><F><P><E><L><S><G><L><P><A><R><V><R><A><A><G><S><S><G><F><E><A><V><E><V><A><W><P><Y><A><E><T><P><E><A><L><A><R><A><A><R><E><A><G><L><R><L><V><L><I><N><T><P><P><G><D><Q><E><K><G><E><M><G><L><G><A><V><P><G><R><Q><A><A><F><R><E><G><L><E><Q><A><V><R><Y><A><K><A><L><G><C><P><R><I><H><L... | Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).<BOP> | Q5T013 |
Q2T9L4 | INSY1_HUMAN | Inhibitory synaptic factor 1 | Homo | <M><N><I><R><G><A><P><D><L><G><Q><P><S><D><D><P><S><S><G><G><E><R><E><R><I><R><Q><R><M><K><M><V><I><G><Q><L><E><G><I><L><R><E><L><K><E><V><A><K><E><L><R><E><V><V><S><Q><I><D><K><L><T><S><D><F><D><F><E><L><E><P><D><D><W><T><T><A><T><V><S><S><T><S><S><S><D><K><A><G><M><G><G><P><F><D><L><G><H><L><D><F><M><T><A><D><I><L><S... | Component of the protein machinery at the inhibitory synapses, probably acting as a scaffold. Inhibitory synapses dampen neuronal activity through postsynaptic hyperpolarization. This synaptic inhibition is fundamental for the functioning of the central nervous system, shaping and orchestrating the flow of information ... | Q2T9L4 |
O43889 | CREB3_HUMAN | Processed cyclic AMP-responsive element-binding protein 3 | Homo | <M><E><L><E><L><D><A><G><D><Q><D><L><L><A><F><L><L><E><E><S><G><D><L><G><T><A><P><D><E><A><V><R><A><P><L><D><W><A><L><P><L><S><E><V><P><S><D><W><E><V><D><D><L><L><C><S><L><L><S><P><P><A><S><L><N><I><L><S><S><S><N><P><C><L><V><H><H><D><H><T><Y><S><L><P><R><E><T><V><S><M><D><L><E><S><E><S><C><R><K><E><G><T><Q><M><T><P><Q... | (Microbial infection) It's transcriptional activity is inhibited by CREBZF in a HCFC1-dependent manner, by the viral transactivator HCV core protein.<BOP> | O43889 |
Q9BUI4 | RPC3_HUMAN | RNA polymerase III 62 kDa subunit | Homo | <M><T><Q><A><E><I><K><L><C><S><L><L><L><Q><E><H><F><G><E><I><V><E><K><I><G><V><H><L><I><R><T><G><S><Q><P><L><R><V><I><A><H><D><T><G><T><S><L><D><Q><V><K><K><A><L><C><V><L><V><Q><H><N><L><V><S><Y><Q><V><H><K><R><G><V><V><E><Y><E><A><Q><C><S><R><V><L><R><M><L><R><Y><P><R><Y><I><Y><T><T><K><T><L><Y><S><D><T><G><E><L><I><V... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA... | Q9BUI4 |
Q15019 | SEPT2_HUMAN | Neural precursor cell expressed developmentally down-regulated protein 5 | Homo | <M><S><K><Q><Q><P><T><Q><F><I><N><P><E><T><P><G><Y><V><G><F><A><N><L><P><N><Q><V><H><R><K><S><V><K><K><G><F><E><F><T><L><M><V><V><G><E><S><G><L><G><K><S><T><L><I><N><S><L><F><L><T><D><L><Y><P><E><R><V><I><P><G><A><A><E><K><I><E><R><T><V><Q><I><E><A><S><T><V><E><I><E><E><R><G><V><K><L><R><L><T><V><V><D><T><P><G><Y><G><D... | Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation . Required for normal organization of the actin cytoskeleton. Pla... | Q15019 |
O75469 | NR1I2_HUMAN | Steroid and xenobiotic receptor | Homo | <M><E><V><R><P><K><E><S><W><N><H><A><D><F><V><H><C><E><D><T><E><S><V><P><G><K><P><S><V><N><A><D><E><E><V><G><G><P><Q><I><C><R><V><C><G><D><K><A><T><G><Y><H><F><N><V><M><T><C><E><G><C><K><G><F><F><R><R><A><M><K><R><N><A><R><L><R><C><P><F><R><K><G><A><C><E><I><T><R><K><T><R><R><Q><C><Q><A><C><R><L><R><K><C><L><E><S><G><M... | Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the antibiotic rifampicin and ... | O75469 |
P08263 | GSTA1_HUMAN | Glutathione S-transferase A1, N-terminally processed | Homo | <M><A><E><K><P><K><L><H><Y><F><N><A><R><G><R><M><E><S><T><R><W><L><L><A><A><A><G><V><E><F><E><E><K><F><I><K><S><A><E><D><L><D><K><L><R><N><D><G><Y><L><M><F><Q><Q><V><P><M><V><E><I><D><G><M><K><L><V><Q><T><R><A><I><L><N><Y><I><A><S><K><Y><N><L><Y><G><K><D><I><K><E><R><A><L><I><D><M><Y><I><E><G><I><A><D><L><G><E><M><I><L... | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) . It also catal... | P08263 |
Q9BQ83 | SLX1_HUMAN | GIY-YIG domain-containing protein 1 | Homo | <M><G><P><A><G><V><A><A><R><P><G><R><F><F><G><V><Y><L><L><Y><C><L><N><P><R><Y><R><G><R><V><Y><V><G><F><T><V><N><T><A><R><R><V><Q><Q><H><N><G><G><R><K><K><G><G><A><W><R><T><S><G><R><G><P><W><E><M><V><L><V><V><H><G><F><P><S><S><V><A><A><L><R><F><E><W><A><W><Q><H><P><H><A><S><R><R><L><A><H><V><G><P><R><L><R><G><E><T><A><F... | Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap st... | Q9BQ83 |
Q8WUM9 | S20A1_HUMAN | Solute carrier family 20 member 1 | Homo | <M><A><T><L><I><T><S><T><T><A><A><T><A><A><S><G><P><L><V><D><Y><L><W><M><L><I><L><G><F><I><I><A><F><V><L><A><F><S><V><G><A><N><D><V><A><N><S><F><G><T><A><V><G><S><G><V><V><T><L><K><Q><A><C><I><L><A><S><I><F><E><T><V><G><S><V><L><L><G><A><K><V><S><E><T><I><R><K><G><L><I><D><V><E><M><Y><N><S><T><Q><G><L><L><M><A><G><S><V... | (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).<BOP> | Q8WUM9 |
Q5J5C9 | DB121_HUMAN | Defensin, beta 121 | Homo | <M><K><L><L><L><L><L><L><T><V><T><L><L><L><A><Q><V><T><P><V><M><K><C><W><G><K><S><G><R><C><R><T><T><C><K><E><S><E><V><Y><Y><I><L><C><K><T><E><A><K><C><C><V><D><P><K><Y><V><P><V><K><P><K><L><T><D><T><N><T><S><L><E><S><T><S><A><V> | Has antibacterial activity.<BOP> | Q5J5C9 |
P15882 | CHIN_HUMAN | Rho GTPase-activating protein 2 | Homo | <M><A><L><T><L><F><D><T><D><E><Y><R><P><P><V><W><K><S><Y><L><Y><Q><L><Q><Q><E><A><P><H><P><R><R><I><T><C><T><C><E><V><E><N><R><P><K><Y><Y><G><R><E><F><H><G><M><I><S><R><E><A><A><D><Q><L><L><I><V><A><E><G><S><Y><L><I><R><E><S><Q><R><Q><P><G><T><Y><T><L><A><L><R><F><G><S><Q><T><R><N><F><R><L><Y><Y><D><G><K><H><F><V><G><E... | GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.<BOP> | P15882 |
Q5JNZ3 | ZN311_HUMAN | Zinc finger protein zfp-31 | Homo | <M><Q><E><V><V><L><L><D><E><S><S><G><P><P><S><Q><L><L><W><T><R><Q><D><T><Q><L><P><Q><E><S><A><L><L><P><A><P><Y><P><A><F><T><K><D><G><S><Q><G><N><L><P><Q><A><D><I><T><L><M><S><Q><A><Q><E><S><V><T><F><E><D><V><A><V><N><F><T><N><R><E><W><Q><C><L><T><Y><A><Q><R><H><L><Y><K><D><V><M><L><E><N><Y><G><N><M><V><S><L><G><F><P><F... | May be involved in transcriptional regulation.<BOP> | Q5JNZ3 |
O95476 | CNEP1_HUMAN | Serine/threonine-protein phosphatase dullard | Homo | <M><M><R><T><Q><C><L><L><G><L><R><T><F><V><A><F><A><A><K><L><W><S><F><F><I><Y><L><L><R><R><Q><I><R><T><V><I><Q><Y><Q><T><V><R><Y><D><I><L><P><L><S><P><V><S><R><N><R><L><A><Q><V><K><R><K><I><L><V><L><D><L><D><E><T><L><I><H><S><H><H><D><G><V><L><R><P><T><V><R><P><G><T><P><P><D><F><I><L><K><V><V><I><D><K><H><P><V><R><F><F... | Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels... | O95476 |
Q8N4G2 | ARL14_HUMAN | ADP-ribosylation factor 7 | Homo | <M><G><S><L><G><S><K><N><P><Q><T><K><Q><A><Q><V><L><L><L><G><L><D><S><A><G><K><S><T><L><L><Y><K><L><K><L><A><K><D><I><T><T><I><P><T><I><G><F><N><V><E><M><I><E><L><E><R><N><L><S><L><T><V><W><D><V><G><G><Q><E><K><M><R><T><V><W><G><C><Y><C><E><N><T><D><G><L><V><Y><V><V><D><S><T><D><K><Q><R><L><E><E><S><Q><R><Q><F><E><H><I... | GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.<BOP> | Q8N4G2 |
Q9BPW9 | DHRS9_HUMAN | Tracheobronchial epithelial cell-specific retinol dehydrogenase | Homo | <M><L><F><W><V><L><G><L><L><I><L><C><G><F><L><W><T><R><K><G><K><L><K><I><E><D><I><T><D><K><Y><I><F><I><T><G><C><D><S><G><F><G><N><L><A><A><R><T><F><D><K><K><G><F><H><V><I><A><A><C><L><T><E><S><G><S><T><A><L><K><A><E><T><S><E><R><L><R><T><V><L><L><D><V><T><D><P><E><N><V><K><R><T><A><Q><W><V><K><N><Q><V><G><E><K><G><L><W... | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone . Also plays a role in the biosynthesis of retinoic acid from retinaldehyde . Can utilize both NADH and NADPH.<BOP> | Q9BPW9 |
P38567 | HYALP_HUMAN | Sperm surface protein PH-20 | Homo | <M><G><V><L><K><F><K><H><I><F><F><R><S><F><V><K><S><S><G><V><S><Q><I><V><F><T><F><L><L><I><P><C><C><L><T><L><N><F><R><A><P><P><V><I><P><N><V><P><F><L><W><A><W><N><A><P><S><E><F><C><L><G><K><F><D><E><P><L><D><M><S><L><F><S><F><I><G><S><P><R><I><N><A><T><G><Q><G><V><T><I><F><Y><V><D><R><L><G><Y><Y><P><Y><I><D><S><I><T><G... | Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulu... | P38567 |
Q9Y5Z0 | BACE2_HUMAN | Theta-secretase | Homo | <M><G><A><L><A><R><A><L><L><L><P><L><L><A><Q><W><L><L><R><A><A><P><E><L><A><P><A><P><F><T><L><P><L><R><V><A><A><A><T><N><R><V><V><A><P><T><P><G><P><G><T><P><A><E><R><H><A><D><G><L><A><L><A><L><E><P><A><L><A><S><P><A><G><A><A><N><F><L><A><M><V><D><N><L><Q><G><D><S><G><R><G><Y><Y><L><E><M><L><I><G><T><P><P><Q><K><L><Q><I... | Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also b... | Q9Y5Z0 |
Q9BWV2 | SPAT9_HUMAN | Testis development protein NYD-SP16 | Homo | <M><P><I><K><P><V><G><W><I><C><G><Q><V><L><K><N><F><S><G><R><I><E><G><I><Q><K><A><I><M><D><L><V><D><E><F><K><D><E><F><P><T><I><L><R><L><S><Q><S><N><Q><K><R><E><P><A><Q><K><T><S><K><I><R><M><A><I><A><L><A><K><I><N><R><A><T><L><I><R><G><L><N><S><I><S><R><S><S><K><S><V><A><K><L><L><H><P><Q><L><A><C><R><L><L><E><L><R><D><I... | May play a role in testicular development/spermatogenesis and may be an important factor in male infertility.<BOP> | Q9BWV2 |
Q9NPJ6 | MED4_HUMAN | Vitamin D3 receptor-interacting protein complex 36 kDa component | Homo | <M><A><A><S><S><S><G><E><K><E><K><E><R><L><G><G><G><L><G><V><A><G><G><N><S><T><R><E><R><L><L><S><A><L><E><D><L><E><V><L><S><R><E><L><I><E><M><L><A><I><S><R><N><Q><K><L><L><Q><A><G><E><E><N><Q><V><L><E><L><L><I><H><R><D><G><E><F><Q><E><L><M><K><L><A><L><N><Q><G><K><I><H><H><E><M><Q><V><L><E><K><E><V><E><K><R><D><S><D><I... | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters... | Q9NPJ6 |
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