accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P60411 | KR109_HUMAN | Keratin-associated protein 18.9 | Homo | <M><A><A><S><T><M><S><I><R><S><S><A><Y><S><D><S><W><Q><V><D><D><C><P><E><S><C><C><E><P><P><C><C><A><T><S><C><C><A><P><A><P><C><L><T><L><V><C><T><P><V><S><R><V><S><S><P><C><C><Q><V><T><C><E><P><S><P><C><Q><S><G><C><T><S><S><C><T><P><S><C><C><Q><Q><S><S><C><Q><P><A><Y><C><T><S><S><P><C><Q><Q><A><C><C><V><P><V><C><C><K><P... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | P60411 |
Q14956 | GPNMB_HUMAN | Hematopoietic growth factor inducible neurokinin-1 type | Homo | <M><E><C><L><Y><Y><F><L><G><F><L><L><L><A><A><R><L><P><L><D><A><A><K><R><F><H><D><V><L><G><N><E><R><P><S><A><Y><M><R><E><H><N><Q><L><N><G><W><S><S><D><E><N><D><W><N><E><K><L><Y><P><V><W><K><R><G><D><M><R><W><K><N><S><W><K><G><G><R><V><Q><A><V><L><T><S><D><S><P><A><L><V><G><S><N><I><T><F><A><V><N><L><I><F><P><R><C><Q><K... | Could be a melanogenic enzyme.<BOP> | Q14956 |
Q6QNY0 | BL1S3_HUMAN | Biogenesis of lysosome-related organelles complex 1 subunit 3 | Homo | <M><A><S><Q><G><R><R><R><R><P><L><R><R><P><E><T><V><V><P><G><E><A><T><E><T><D><S><E><R><S><A><S><S><S><E><E><E><E><L><Y><L><G><P><S><G><P><T><R><G><R><P><T><G><L><R><V><A><G><E><A><A><E><T><D><S><E><P><E><P><E><P><E><P><T><A><A><P><R><D><L><P><P><L><V><V><Q><R><E><S><A><E><E><A><W><G><T><E><E><A><P><A><P><A><P><A><R><S... | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery ... | Q6QNY0 |
Q9NZG7 | NINJ2_HUMAN | Nerve injury-induced protein 2 | Homo | <M><E><S><A><R><E><N><I><D><L><Q><P><G><S><S><D><P><R><S><Q><P><I><N><L><N><H><Y><A><T><K><K><S><V><A><E><S><M><L><D><V><A><L><F><M><S><N><A><M><R><L><K><A><V><L><E><Q><G><P><S><S><H><Y><Y><T><T><L><V><T><L><I><S><L><S><L><L><L><Q><V><V><I><G><V><L><L><V><V><I><A><R><L><N><L><N><E><V><E><K><Q><W><R><L><N><Q><L><N><N><A... | Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues.<BOP> | Q9NZG7 |
Q13426 | XRCC4_HUMAN | Protein XRCC4, C-terminus | Homo | <M><E><R><K><I><S><R><I><H><L><V><S><E><P><S><I><T><H><F><L><Q><V><S><W><E><K><T><L><E><S><G><F><V><I><T><L><T><D><G><H><S><A><W><T><G><T><V><S><E><S><E><I><S><Q><E><A><D><D><M><A><M><E><K><G><K><Y><V><G><E><L><R><K><A><L><L><S><G><A><G><P><A><D><V><Y><T><F><N><F><S><K><E><S><C><Y><F><F><F><E><K><N><L><K><D><V><S><F><R... | Acts as an activator of the phospholipid scramblase activity of XKR4 . This form, which is generated upon caspase-3 (CASP3) cleavage, translocates into the cytoplasm and interacts with XKR4, thereby promoting phosphatidylserine scramblase activity of XKR4 and leading to phosphatidylserine exposure on apoptotic cell sur... | Q13426 |
Q96SN7 | ORAI2_HUMAN | Transmembrane protein 142B | Homo | <M><S><A><E><L><N><V><P><I><D><P><S><A><P><A><C><P><E><P><G><H><K><G><M><D><Y><R><D><W><V><R><R><S><Y><L><E><L><V><T><S><N><H><H><S><V><Q><A><L><S><W><R><K><L><Y><L><S><R><A><K><L><K><A><S><S><R><T><S><A><L><L><S><G><F><A><M><V><A><M><V><E><V><Q><L><E><T><Q><Y><Q><Y><P><R><P><L><L><I><A><F><S><A><C><T><T><V><L><V><A><V... | Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1.<BOP> | Q96SN7 |
P07919 | QCR6_HUMAN | Ubiquinol-cytochrome c reductase complex 11 kDa protein | Homo | <M><G><L><E><D><E><Q><K><M><L><T><E><S><G><D><P><E><E><E><E><E><E><E><E><E><L><V><D><P><L><T><T><V><R><E><Q><C><E><Q><L><E><K><C><V><K><A><R><E><R><L><E><L><C><D><E><R><V><S><S><R><S><H><T><E><E><D><C><T><E><E><L><F><D><F><L><H><A><R><D><H><C><V><A><H><K><L><F><N><N><L><K> | Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidor... | P07919 |
P01611 | KVD12_HUMAN | Ig kappa chain V-I region Wes | Homo | <M><D><M><M><V><P><A><Q><L><L><G><L><L><L><L><W><F><P><G><S><R><C><D><I><Q><M><T><Q><S><P><S><S><V><S><A><S><V><G><D><R><V><T><I><T><C><R><A><S><Q><G><I><S><S><W><L><A><W><Y><Q><Q><K><P><G><K><A><P><K><L><L><I><Y><A><A><S><S><L><Q><S><G><V><P><S><R><F><S><G><S><G><S><G><T><D><F><T><L><T><I><S><S><L><Q><P><E><D><F><A><T... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01611 |
P50219 | MNX1_HUMAN | Homeobox protein HB9 | Homo | <M><E><K><S><K><N><F><R><I><D><A><L><L><A><V><D><P><P><R><A><A><S><A><Q><S><A><P><L><A><L><V><T><S><L><A><A><A><A><S><G><T><G><G><G><G><G><G><G><G><A><S><G><G><T><S><G><S><C><S><P><A><S><S><E><P><P><A><A><P><A><D><R><L><R><A><E><S><P><S><P><P><R><L><L><A><A><H><C><A><L><L><P><K><P><G><F><L><G><A><G><G><G><G><G><G><T><G... | Putative transcription factor involved in pancreas development and function.<BOP> | P50219 |
O43709 | BUD23_HUMAN | rRNA methyltransferase and ribosome maturation factor | Homo | <M><A><S><R><G><R><R><P><E><H><G><G><P><P><E><L><F><Y><D><E><T><E><A><R><K><Y><V><R><N><S><R><M><I><D><I><Q><T><R><M><A><G><R><A><L><E><L><L><Y><L><P><E><N><K><P><C><Y><L><L><D><I><G><C><G><T><G><L><S><G><S><Y><L><S><D><E><G><H><Y><W><V><G><L><D><I><S><P><A><M><L><D><E><A><V><D><R><E><I><E><G><D><L><L><L><G><D><M><G><Q... | S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA . Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently ... | O43709 |
Q4G0N4 | NAKD2_HUMAN | NAD kinase domain-containing protein 1, mitochondrial | Homo | <M><T><C><Y><R><G><F><L><L><G><S><C><C><R><V><A><G><G><R><A><A><A><L><R><G><P><G><A><G><G><P><A><A><R><P><R><L><G><G><D><G><G><G><R><R><H><L><G><Q><G><Q><P><R><E><L><A><G><C><G><S><R><A><D><G><G><F><R><P><S><R><V><V><V><V><A><K><T><T><R><Y><E><F><E><Q><Q><R><Y><R><Y><A><E><L><S><E><E><D><L><K><Q><L><L><A><L><K><G><S><S... | Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. Also has weak NADH kinase activity in vitro; however NADH kinase activity is much weaker than the NAD(+) kinase activity and may not be relevant in vivo.<BOP> | Q4G0N4 |
Q8WXF8 | DEDD2_HUMAN | FADD-like anti-apoptotic molecule 3 | Homo | <M><A><L><S><G><S><T><P><A><P><C><W><E><E><D><E><C><L><D><Y><Y><G><M><L><S><L><H><R><M><F><E><V><V><G><G><Q><L><T><E><C><E><L><E><L><L><A><F><L><L><D><E><A><P><G><A><A><G><G><L><A><R><A><R><S><G><L><E><L><L><L><E><L><E><R><R><G><Q><C><D><E><S><N><L><R><L><L><G><Q><L><L><R><V><L><A><R><H><D><L><L><P><H><L><A><R><K><R><R... | May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.<BOP> | Q8WXF8 |
P43320 | CRBB2_HUMAN | Beta-crystallin Bp | Homo | <M><A><S><D><H><Q><T><Q><A><G><K><P><Q><S><L><N><P><K><I><I><I><F><E><Q><E><N><F><Q><G><H><S><H><E><L><N><G><P><C><P><N><L><K><E><T><G><V><E><K><A><G><S><V><L><V><Q><A><G><P><W><V><G><Y><E><Q><A><N><C><K><G><E><Q><F><V><F><E><K><G><E><Y><P><R><W><D><S><W><T><S><S><R><R><T><D><S><L><S><S><L><R><P><I><K><V><D><S><Q><E><H... | Crystallins are the dominant structural components of the vertebrate eye lens.<BOP> | P43320 |
Q9BSW7 | SYT17_HUMAN | Synaptotagmin XVII | Homo | <M><A><Y><I><Q><L><E><P><L><N><E><G><F><L><S><R><I><S><G><L><L><L><C><R><W><T><C><R><H><C><C><Q><K><C><Y><E><S><S><C><C><Q><S><S><E><D><E><V><E><I><L><G><P><F><P><A><Q><T><P><P><W><L><M><A><S><R><S><S><D><K><D><G><D><S><V><H><T><A><S><E><V><P><L><T><P><R><T><N><S><P><D><G><R><R><S><S><S><D><T><S><K><S><T><Y><S><L><T><R... | Plays a role in dendrite formation by melanocytes .<BOP> | Q9BSW7 |
P62072 | TIM10_HUMAN | Mitochondrial import inner membrane translocase subunit Tim10 | Homo | <M><D><P><L><R><A><Q><Q><L><A><A><E><L><E><V><E><M><M><A><D><M><Y><N><R><M><T><S><A><C><H><R><K><C><V><P><P><H><Y><K><E><A><E><L><S><K><G><E><S><V><C><L><D><R><C><V><S><K><Y><L><D><I><H><E><R><M><G><K><K><L><T><E><L><S><M><Q><D><E><E><L><M><K><R><V><Q><Q><S><S><G><P><A> | Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. ... | P62072 |
P05388 | RLA0_HUMAN | Large ribosomal subunit protein uL10 | Homo | <M><P><R><E><D><R><A><T><W><K><S><N><Y><F><L><K><I><I><Q><L><L><D><D><Y><P><K><C><F><I><V><G><A><D><N><V><G><S><K><Q><M><Q><Q><I><R><M><S><L><R><G><K><A><V><V><L><M><G><K><N><T><M><M><R><K><A><I><R><G><H><L><E><N><N><P><A><L><E><K><L><L><P><H><I><R><G><N><V><G><F><V><F><T><K><E><D><L><T><E><I><R><D><M><L><L><A><N><K><V... | Ribosomal protein P0 is the functional equivalent of E.coli protein L10.<BOP> | P05388 |
Q9H7H0 | MET17_HUMAN | Protein RSM22 homolog, mitochondrial | Homo | <M><A><A><A><L><K><C><L><L><T><L><G><R><W><C><P><G><L><G><V><A><P><Q><A><R><A><L><A><A><L><V><P><G><V><T><Q><V><D><N><K><S><G><F><L><Q><K><R><P><H><R><Q><H><P><G><I><L><K><L><P><H><V><R><L><P><Q><A><L><A><N><G><A><Q><L><L><L><L><G><S><A><G><P><T><M><E><N><Q><V><Q><T><L><T><S><Y><L><W><S><R><H><L><P><V><E><P><E><E><L><Q... | Probable S-adenosyl-L-methionine-dependent RNA methyltransferase required to stabilize the mitochondrial small ribosomal subunit (mt-SSU). Required for protein translation in mitochondria.<BOP> | Q9H7H0 |
Q16875 | F263_HUMAN | Fructose-2,6-bisphosphatase | Homo | <M><P><L><E><L><T><Q><S><R><V><Q><K><I><W><V><P><V><D><H><R><P><S><L><P><R><S><C><G><P><K><L><T><N><S><P><T><V><I><V><M><V><G><L><P><A><R><G><K><T><Y><I><S><K><K><L><T><R><Y><L><N><W><I><G><V><P><T><K><V><F><N><V><G><E><Y><R><R><E><A><V><K><Q><Y><S><S><Y><N><F><F><R><P><D><N><E><E><A><M><K><V><R><K><Q><C><A><L><A><A><L... | Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate.<BOP> | Q16875 |
Q9H361 | PABP3_HUMAN | Testis-specific poly(A)-binding protein | Homo | <M><N><P><S><T><P><S><Y><P><T><A><S><L><Y><V><G><D><L><H><P><D><V><T><E><A><M><L><Y><E><K><F><S><P><A><G><P><I><L><S><I><R><I><C><R><D><L><I><T><S><G><S><S><N><Y><A><Y><V><N><F><Q><H><T><K><D><A><E><H><A><L><D><T><M><N><F><D><V><I><K><G><K><P><V><R><I><M><W><S><Q><R><D><P><S><L><R><K><S><G><V><G><N><I><F><V><K><N><L><D... | Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Binds poly(A) with a slightly lower affinity as compared to PABPC1.<BOP> | Q9H361 |
P20827 | EFNA1_HUMAN | Ephrin-A1, secreted form | Homo | <M><E><F><L><W><A><P><L><L><G><L><C><C><S><L><A><A><A><D><R><H><T><V><F><W><N><S><S><N><P><K><F><R><N><E><D><Y><T><I><H><V><Q><L><N><D><Y><V><D><I><I><C><P><H><Y><E><D><H><S><V><A><D><A><A><M><E><Q><Y><I><L><Y><L><V><E><H><E><E><Y><Q><L><C><Q><P><Q><S><K><D><Q><V><R><W><Q><C><N><R><P><S><A><K><H><G><P><E><K><L><S><E><K... | Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into nei... | P20827 |
Q96C86 | DCPS_HUMAN | Scavenger mRNA-decapping enzyme DcpS | Homo | <M><A><D><A><A><P><Q><L><G><K><R><K><R><E><L><D><V><E><E><A><H><A><A><S><T><E><E><K><E><A><G><V><G><N><G><T><C><A><P><V><R><L><P><F><S><G><F><R><L><Q><K><V><L><R><E><S><A><R><D><K><I><I><F><L><H><G><K><V><N><E><A><S><G><D><G><D><G><E><D><A><V><V><I><L><E><K><T><P><F><Q><V><E><Q><V><A><Q><L><L><T><G><S><P><E><L><Q><L><Q... | Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonu... | Q96C86 |
Q96B36 | AKTS1_HUMAN | 40 kDa proline-rich AKT substrate | Homo | <M><A><S><G><R><P><E><E><L><W><E><A><V><V><G><A><A><E><R><F><R><A><R><T><G><T><E><L><V><L><L><T><A><A><P><P><P><P><P><R><P><G><P><C><A><Y><A><A><H><G><R><G><A><L><A><E><A><A><R><R><C><L><H><D><I><A><L><A><H><R><A><A><T><A><A><R><P><P><A><P><P><P><A><P><Q><P><P><S><P><T><P><S><P><P><R><P><T><L><A><R><E><D><N><E><E><D><E... | Subunit of mTORC1, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase t... | Q96B36 |
Q13203 | MYBPH_HUMAN | H-protein | Homo | <M><M><E><K><N><T><S><E><G><P><A><C><S><P><E><E><T><A><S><E><S><A><K><V><P><T><A><E><P><P><G><E><V><A><V><S><E><S><T><R><E><E><Q><V><P><K><P><Q><A><P><A><P><Q><A><P><T><A><S><T><A><T><K><P><A><P><P><S><E><D><V><P><S><A><P><L><L><L><T><L><D><D><V><S><S><S><S><V><T><V><S><W><E><P><P><E><R><L><G><R><L><G><L><Q><G><Y><V><L... | Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.<BOP> | Q13203 |
O14813 | PHX2A_HUMAN | Paired-like homeobox 2A | Homo | <M><D><Y><S><Y><L><N><S><Y><D><S><C><V><A><A><M><E><A><S><A><Y><G><D><F><G><A><C><S><Q><P><G><G><F><Q><Y><S><P><L><R><P><A><F><P><A><A><G><P><P><C><P><A><L><G><S><S><N><C><A><L><G><A><L><R><D><H><Q><P><A><P><Y><S><A><V><P><Y><K><F><F><P><E><P><S><G><L><H><E><K><R><K><Q><R><R><I><R><T><T><F><T><S><A><Q><L><K><E><L><E><R... | May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype.<BOP> | O14813 |
P50579 | MAP2_HUMAN | Peptidase M | Homo | <M><A><G><V><E><E><V><A><A><S><G><S><H><L><N><G><D><L><D><P><D><D><R><E><E><G><A><A><S><T><A><E><E><A><A><K><K><K><R><R><K><K><K><K><S><K><G><P><S><A><A><G><E><Q><E><P><D><K><E><S><G><A><S><V><D><E><V><A><R><Q><L><E><R><S><A><L><E><D><K><E><R><D><E><D><D><E><D><G><D><G><D><G><D><G><A><T><G><K><K><K><K><K><K><K><K><K><R... | Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.<BOP> | P50579 |
Q8NG04 | S2610_HUMAN | Putative solute carrier family 26 member 10P | Homo | <M><R><L><D><L><A><S><L><M><S><A><P><K><S><L><G><S><A><F><K><S><W><R><L><D><K><A><P><S><P><Q><H><T><F><P><S><T><S><I><P><G><M><A><F><A><L><L><A><S><V><P><P><V><F><G><L><Y><T><S><F><F><P><V><L><I><Y><S><L><L><G><T><G><R><H><L><S><T><G><T><F><A><I><L><S><L><M><T><G><S><A><V><E><R><L><V><P><E><P><L><V><G><N><L><S><G><I><E... | Chloride/bicarbonate exchanger.<BOP> | Q8NG04 |
Q6ZNG0 | ZN620_HUMAN | Zinc finger protein 620 | Homo | <M><F><Q><T><A><W><R><Q><E><P><V><T><F><E><D><V><A><V><Y><F><T><Q><N><E><W><A><S><L><D><S><V><Q><R><A><L><Y><R><E><V><M><L><E><N><Y><A><N><V><A><S><L><A><F><P><F><T><T><P><V><L><V><S><Q><L><E><Q><G><E><L><P><W><G><L><D><P><W><E><P><M><G><R><E><A><L><R><G><I><C><P><G><D><E><A><R><T><E><K><E><G><L><T><P><K><D><H><V><S><K... | May be involved in transcriptional regulation.<BOP> | Q6ZNG0 |
O75971 | SNPC5_HUMAN | snRNA-activating protein complex 19 kDa subunit | Homo | <M><L><S><R><L><Q><E><L><R><K><E><E><E><T><L><L><R><L><K><A><A><L><H><D><Q><L><N><R><L><K><V><E><E><L><A><L><Q><S><M><I><S><S><R><R><G><D><E><M><L><S><S><H><T><V><P><E><Q><S><H><D><M><L><V><H><V><D><N><E><A><S><I><N><Q><T><T><L><E><L><S><T><K><S><H><V><T><E><E><E><E><E><E><E><E><E><E><S><D><S> | Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.<BOP> | O75971 |
Q07020 | RL18_HUMAN | Large ribosomal subunit protein eL18 | Homo | <M><G><V><D><I><R><H><N><K><D><R><K><V><R><R><K><E><P><K><S><Q><D><I><Y><L><R><L><L><V><K><L><Y><R><F><L><A><R><R><T><N><S><T><F><N><Q><V><V><L><K><R><L><F><M><S><R><T><N><R><P><P><L><S><L><S><R><M><I><R><K><M><K><L><P><G><R><E><N><K><T><A><V><V><V><G><T><I><T><D><D><V><R><V><Q><E><V><P><K><L><K><V><C><A><L><R><V><T><S... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP> | Q07020 |
Q71F23 | CENPU_HUMAN | Polo-box-interacting protein 1 | Homo | <M><A><P><R><G><R><R><R><P><R><P><H><R><S><E><G><A><R><R><S><K><N><T><L><E><R><T><H><S><M><K><D><K><A><G><Q><K><C><K><P><I><D><V><F><D><F><P><D><N><S><D><V><S><S><I><G><R><L><G><E><N><E><K><D><E><E><T><Y><E><T><F><D><P><P><L><H><S><T><A><I><Y><A><D><E><E><E><F><S><K><H><C><G><L><S><L><S><S><T><P><P><G><K><E><A><K><R><S... | Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA in... | Q71F23 |
Q96IS3 | RAX2_HUMAN | Retina and anterior neural fold homeobox-like protein 1 | Homo | <M><F><L><S><P><G><E><G><P><A><T><E><G><G><G><L><G><P><G><E><E><A><P><K><K><K><H><R><R><N><R><T><T><F><T><T><Y><Q><L><H><Q><L><E><R><A><F><E><A><S><H><Y><P><D><V><Y><S><R><E><E><L><A><A><K><V><H><L><P><E><V><R><V><Q><V><W><F><Q><N><R><R><A><K><W><R><R><Q><E><R><L><E><S><G><S><G><A><V><A><A><P><R><L><P><E><A><P><A><L><P... | May be involved in modulating the expression of photoreceptor specific genes. Binds to the Ret-1 and Bat-1 element within the rhodopsin promoter.<BOP> | Q96IS3 |
Q13247 | SRSF6_HUMAN | Splicing factor, arginine/serine-rich 6 | Homo | <M><P><R><V><Y><I><G><R><L><S><Y><N><V><R><E><K><D><I><Q><R><F><F><S><G><Y><G><R><L><L><E><V><D><L><K><N><G><Y><G><F><V><E><F><E><D><S><R><D><A><D><D><A><V><Y><E><L><N><G><K><E><L><C><G><E><R><V><I><V><E><H><A><R><G><P><R><R><D><R><D><G><Y><S><Y><G><S><R><S><G><G><G><G><Y><S><S><R><R><T><S><G><R><D><K><Y><G><P><P><V><R... | Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratin... | Q13247 |
Q5R387 | PA2GC_HUMAN | Phosphatidylcholine 2-acylhydrolase-like protein GIIC | Homo | <M><K><V><I><A><I><L><T><L><L><L><F><C><S><P><T><H><S><S><F><W><Q><F><Q><R><R><V><K><H><I><T><G><R><S><A><F><F><S><Y><Y><G><Y><G><C><Y><C><G><L><G><D><K><G><I><P><V><D><D><T><D><R><H><S><P><S><S><P><S><P><Y><E><K><L><K><E><F><S><C><Q><P><V><L><N><S><Y><Q><F><H><I><V><N><G><A><V><V><C><G><C><T><L><G><P><G><A><S><C><H><C... | Inactive phospholipase.<BOP> | Q5R387 |
Q9UJW0 | DCTN4_HUMAN | Dynactin subunit p62 | Homo | <M><A><S><L><L><Q><S><D><R><V><L><Y><L><V><Q><G><E><K><K><V><R><A><P><L><S><Q><L><Y><F><C><R><Y><C><S><E><L><R><S><L><E><C><V><S><H><E><V><D><S><H><Y><C><P><S><C><L><E><N><M><P><S><A><E><A><K><L><K><K><N><R><C><A><N><C><F><D><C><P><G><C><M><H><T><L><S><T><R><A><T><S><I><S><T><Q><L><P><D><D><P><A><K><T><T><M><K><K><A><Y... | Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.<BOP> | Q9UJW0 |
P05120 | PAI2_HUMAN | Urokinase inhibitor | Homo | <M><E><D><L><C><V><A><N><T><L><F><A><L><N><L><F><K><H><L><A><K><A><S><P><T><Q><N><L><F><L><S><P><W><S><I><S><S><T><M><A><M><V><Y><M><G><S><R><G><S><T><E><D><Q><M><A><K><V><L><Q><F><N><E><V><G><A><N><A><V><T><P><M><T><P><E><N><F><T><S><C><G><F><M><Q><Q><I><Q><K><G><S><Y><P><D><A><I><L><Q><A><Q><A><A><D><K><I><H><S><S><F... | Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.<BOP> | P05120 |
P31274 | HXC9_HUMAN | Homeobox protein Hox-3B | Homo | <M><S><A><T><G><P><I><S><N><Y><Y><V><D><S><L><I><S><H><D><N><E><D><L><L><A><S><R><F><P><A><T><G><A><H><P><A><A><A><R><P><S><G><L><V><P><D><C><S><D><F><P><S><C><S><F><A><P><K><P><A><V><F><S><T><S><W><A><P><V><P><S><Q><S><S><V><V><Y><H><P><Y><G><P><Q><P><H><L><G><A><D><T><R><Y><M><R><T><W><L><E><P><L><S><G><A><V><S><F><P... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P31274 |
Q93098 | WNT8B_HUMAN | Protein Wnt-8b | Homo | <M><F><L><S><K><P><S><V><Y><I><C><L><F><T><C><V><L><Q><L><S><H><S><W><S><V><N><N><F><L><M><T><G><P><K><A><Y><L><I><Y><S><S><S><V><A><A><G><A><Q><S><G><I><E><E><C><K><Y><Q><F><A><W><D><R><W><N><C><P><E><R><A><L><Q><L><S><S><H><G><G><L><R><S><A><N><R><E><T><A><F><V><H><A><I><S><S><A><G><V><M><Y><T><L><T><R><N><C><S><L><G... | Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.<BOP> | Q93098 |
Q8NH37 | OR4C3_HUMAN | Olfactory receptor OR11-98 | Homo | <M><D><I><P><Q><N><I><T><E><F><F><M><L><G><L><S><Q><N><S><E><V><Q><R><V><L><F><V><V><F><L><L><I><Y><V><V><T><V><C><G><N><M><L><I><V><V><T><I><T><S><S><P><T><L><A><S><P><V><Y><F><F><L><A><N><L><S><F><I><D><T><F><Y><S><S><S><M><A><P><K><L><I><A><D><S><L><Y><E><G><R><T><I><S><Y><E><C><C><M><A><Q><L><F><G><A><H><F><L><G><G... | Odorant receptor.<BOP> | Q8NH37 |
P01588 | EPO_HUMAN | Erythropoietin | Homo | <M><G><V><H><E><C><P><A><W><L><W><L><L><L><S><L><L><S><L><P><L><G><L><P><V><L><G><A><P><P><R><L><I><C><D><S><R><V><L><E><R><Y><L><L><E><A><K><E><A><E><N><I><T><T><G><C><A><E><H><C><S><L><N><E><N><I><T><V><P><D><T><K><V><N><F><Y><A><W><K><R><M><E><V><G><Q><Q><A><V><E><V><W><Q><G><L><A><L><L><S><E><A><V><L><R><G><Q><A><L... | Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.<BOP> | P01588 |
Q6TDU7 | DNAI7_HUMAN | Protein phosphatase 1 regulatory subunit 54 | Homo | <M><S><G><S><K><K><K><K><V><T><K><A><E><R><L><K><L><L><Q><E><E><E><E><R><R><L><K><E><E><E><E><A><R><L><K><Y><E><K><E><E><M><E><R><L><E><I><Q><R><I><E><K><E><K><W><H><R><L><E><A><K><D><L><E><R><R><N><E><E><L><E><E><L><Y><L><L><E><R><C><F><P><E><A><E><K><L><K><Q><E><T><K><L><L><S><Q><W><K><H><Y><I><Q><C><D><G><S><P><D><P... | Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function. May also act as a cell cycle regulator.<BOP> | Q6TDU7 |
Q7Z7M8 | B3GN8_HUMAN | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 | Homo | <M><R><C><P><K><C><L><L><C><L><S><A><L><L><T><L><L><G><L><K><V><Y><I><E><W><T><S><E><S><R><L><S><K><A><Y><P><S><P><R><G><T><P><P><S><P><T><P><A><N><P><E><P><T><L><P><A><N><L><S><T><R><L><G><Q><T><I><P><L><P><F><A><Y><W><N><Q><Q><Q><W><R><L><G><S><L><P><S><G><D><S><T><E><T><G><G><C><Q><A><W><G><A><A><A><A><T><E><I><P><D... | Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans. Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.<BOP> | Q7Z7M8 |
O43464 | HTRA2_HUMAN | Serine proteinase OMI | Homo | <M><A><A><P><R><A><G><R><G><A><G><W><S><L><R><A><W><R><A><L><G><G><I><R><W><G><R><R><P><R><L><T><P><D><L><R><A><L><L><T><S><G><T><S><D><P><R><A><R><V><T><Y><G><T><P><S><L><W><A><R><L><S><V><G><V><T><E><P><R><A><C><L><T><S><G><T><P><G><P><R><A><Q><L><T><A><V><T><P><D><T><R><T><R><E><A><S><E><N><S><G><T><R><S><R><A><W><L... | Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, c... | O43464 |
Q9BRL7 | SC22C_HUMAN | SEC22 vesicle-trafficking protein-like 3 | Homo | <M><S><V><I><F><F><A><C><V><V><R><V><R><D><G><L><P><L><S><A><S><T><D><F><Y><H><T><Q><D><F><L><E><W><R><R><R><L><K><S><L><A><L><R><L><A><Q><Y><P><G><R><G><S><A><E><G><C><D><F><S><I><H><F><S><S><F><G><D><V><A><C><M><A><I><C><S><C><Q><C><P><A><A><M><A><F><C><F><L><E><T><L><W><W><E><F><T><A><S><Y><D><T><T><C><I><G><L><A><S... | May be involved in vesicle transport between the ER and the Golgi complex.<BOP> | Q9BRL7 |
P19320 | VCAM1_HUMAN | INCAM-100 | Homo | <M><P><G><K><M><V><V><I><L><G><A><S><N><I><L><W><I><M><F><A><A><S><Q><A><F><K><I><E><T><T><P><E><S><R><Y><L><A><Q><I><G><D><S><V><S><L><T><C><S><T><T><G><C><E><S><P><F><F><S><W><R><T><Q><I><D><S><P><L><N><G><K><V><T><N><E><G><T><T><S><T><L><T><M><N><P><V><S><F><G><N><E><H><S><Y><L><C><T><A><T><C><E><S><R><K><L><E><K><G... | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leuko... | P19320 |
P18428 | LBP_HUMAN | Lipopolysaccharide-binding protein | Homo | <M><G><A><L><A><R><A><L><P><S><I><L><L><A><L><L><L><T><S><T><P><E><A><L><G><A><N><P><G><L><V><A><R><I><T><D><K><G><L><Q><Y><A><A><Q><E><G><L><L><A><L><Q><S><E><L><L><R><I><T><L><P><D><F><T><G><D><L><R><I><P><H><V><G><R><G><R><Y><E><F><H><S><L><N><I><H><S><C><E><L><L><H><S><A><L><R><P><V><P><G><Q><G><L><S><L><S><I><S><D... | Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria . Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacter... | P18428 |
O43557 | TNF14_HUMAN | Tumor necrosis factor ligand superfamily member 14, soluble form | Homo | <M><E><E><S><V><V><R><P><S><V><F><V><V><D><G><Q><T><D><I><P><F><T><R><L><G><R><S><H><R><R><Q><S><C><S><V><A><R><V><G><L><G><L><L><L><L><L><M><G><A><G><L><A><V><Q><G><W><F><L><L><Q><L><H><W><R><L><G><E><M><V><T><R><L><P><D><G><P><A><G><S><W><E><Q><L><I><Q><E><R><R><S><H><E><V><N><P><A><A><H><L><T><G><A><N><S><S><L><T><G... | Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Acts as a ligand for TNFRSF14/HVEM . Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production .<BOP> | O43557 |
P14866 | HNRPL_HUMAN | Heterogeneous nuclear ribonucleoprotein L | Homo | <M><S><R><R><L><L><P><R><A><E><K><R><R><R><R><L><E><Q><R><Q><Q><P><D><E><Q><R><R><R><S><G><A><M><V><K><M><A><A><A><G><G><G><G><G><G><G><R><Y><Y><G><G><G><S><E><G><G><R><A><P><K><R><L><K><T><D><N><A><G><D><Q><H><G><G><G><G><G><G><G><G><G><A><G><A><A><G><G><G><G><G><G><E><N><Y><D><D><P><H><K><T><P><A><S><P><V><V><H><I><R... | Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements . Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts . Associates, together with A... | P14866 |
Q9BPX6 | MICU1_HUMAN | Calcium-binding atopy-related autoantigen 1 | Homo | <M><F><R><L><N><S><L><S><A><L><A><E><L><A><V><G><S><R><W><Y><H><G><G><S><Q><P><I><Q><I><R><R><R><L><M><M><V><A><F><L><G><A><S><A><V><T><A><S><T><G><L><L><W><K><R><A><H><A><E><S><P><P><C><V><D><N><L><K><S><D><I><G><D><K><G><K><N><K><D><E><G><D><V><C><N><H><E><K><K><T><A><D><L><A><P><H><P><E><E><K><K><K><K><R><S><G><F><R... | Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains . MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptak... | Q9BPX6 |
Q5GAN3 | RNS13_HUMAN | Probable inactive ribonuclease-like protein 13 | Homo | <M><A><P><A><V><T><R><L><L><F><L><Q><L><V><L><G><P><T><L><V><M><D><I><K><M><Q><I><G><S><R><N><F><Y><T><L><S><I><D><Y><P><R><V><N><Y><P><K><G><F><R><G><Y><C><N><G><L><M><S><Y><M><R><G><K><M><Q><N><S><D><C><P><K><I><H><Y><V><I><H><A><P><W><K><A><I><Q><K><F><C><K><Y><S><D><S><F><C><E><N><Y><N><E><Y><C><T><L><T><Q><D><S><L... | Does not exhibit any ribonuclease activity.<BOP> | Q5GAN3 |
Q9NT62 | ATG3_HUMAN | Protein PC3-96 | Homo | <M><Q><N><V><I><N><T><V><K><G><K><A><L><E><V><A><E><Y><L><T><P><V><L><K><E><S><K><F><K><E><T><G><V><I><T><P><E><E><F><V><A><A><G><D><H><L><V><H><H><C><P><T><W><Q><W><A><T><G><E><E><L><K><V><K><A><Y><L><P><T><G><K><Q><F><L><V><T><K><N><V><P><C><Y><K><R><C><K><Q><M><E><Y><S><D><E><L><E><A><I><I><E><E><D><D><G><D><G><G><W... | E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role o... | Q9NT62 |
Q8N7A1 | KLDC1_HUMAN | Kelch domain-containing protein 1 | Homo | <M><A><D><S><Q><L><F><C><V><A><E><E><R><S><G><H><C><A><V><V><D><G><N><F><L><Y><V><W><G><G><Y><V><S><I><E><D><N><E><V><Y><L><P><N><D><E><I><W><T><Y><D><I><D><S><G><L><W><R><M><H><L><M><E><G><E><L><P><A><S><M><S><G><S><C><G><A><C><I><N><G><K><L><Y><I><F><G><G><Y><D><D><K><G><Y><S><N><R><L><Y><F><V><N><L><R><T><R><D><E><T... | Substrate-recognition component of a Cul5-RING (CRL5) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation . The C-degron recognized by the DesCEND pat... | Q8N7A1 |
Q96JP5 | ZFP91_HUMAN | Zinc finger protein 91 homolog | Homo | <M><P><G><E><T><E><E><P><R><P><P><E><Q><Q><D><Q><E><G><G><E><A><A><K><A><A><P><E><E><P><Q><Q><R><P><P><E><A><V><A><A><A><P><A><G><T><T><S><S><R><V><L><R><G><G><R><D><R><G><R><A><A><A><A><A><A><A><A><A><V><S><R><R><R><K><A><E><Y><P><R><R><R><R><S><S><P><S><A><R><P><P><D><V><P><G><Q><Q><P><Q><A><A><K><S><P><S><P><V><Q><G... | Atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.<BOP> | Q96JP5 |
Q9Y2B0 | CNPY2_HUMAN | Transmembrane protein 4 | Homo | <M><K><G><W><G><W><L><A><L><L><L><G><A><L><L><G><T><A><W><A><R><R><S><Q><D><L><H><C><G><A><C><R><A><L><V><D><E><L><E><W><E><I><A><Q><V><D><P><K><K><T><I><Q><M><G><S><F><R><I><N><P><D><G><S><Q><S><V><V><E><V><P><Y><A><R><S><E><A><H><L><T><E><L><L><E><E><I><C><D><R><M><K><E><Y><G><E><Q><I><D><P><S><T><H><R><K><N><Y><V><R... | Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.<BOP> | Q9Y2B0 |
Q99417 | MYCBP_HUMAN | Associate of Myc 1 | Homo | <M><A><H><Y><K><A><A><D><S><K><R><E><Q><F><R><R><Y><L><E><K><S><G><V><L><D><T><L><T><K><V><L><V><A><L><Y><E><E><P><E><K><P><N><S><A><L><D><F><L><K><H><H><L><G><A><A><T><P><E><N><P><E><I><E><L><L><R><L><E><L><A><E><M><K><E><K><Y><E><A><I><V><E><E><N><K><K><L><K><A><K><L><A><Q><Y><E><P><P><Q><E><E><K><R><A><E> | May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC.<BOP> | Q99417 |
O95256 | I18RA_HUMAN | Interleukin-18 receptor beta | Homo | <M><L><C><L><G><W><I><F><L><W><L><V><A><G><E><R><I><K><G><F><N><I><S><G><C><S><T><K><K><L><L><W><T><Y><S><T><R><S><E><E><E><F><V><L><F><C><D><L><P><E><P><Q><K><S><H><F><C><H><R><N><R><L><S><P><K><Q><V><P><E><H><L><P><F><M><G><S><N><D><L><S><D><V><Q><W><Y><Q><Q><P><S><N><G><D><P><L><E><D><I><R><K><S><Y><P><H><I><I><Q><D... | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation . May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).<BOP> | O95256 |
Q9UBH6 | XPR1_HUMAN | Xenotropic and polytropic murine leukemia virus receptor X3 | Homo | <M><K><F><A><E><H><L><S><A><H><I><T><P><E><W><R><K><Q><Y><I><Q><Y><E><A><F><K><D><M><L><Y><S><A><Q><D><Q><A><P><S><V><E><V><T><D><E><D><T><V><K><R><Y><F><A><K><F><E><E><K><F><F><Q><T><C><E><K><E><L><A><K><I><N><T><F><Y><S><E><K><L><A><E><A><Q><R><R><F><A><T><L><Q><N><E><L><Q><S><S><L><D><A><Q><K><E><S><T><G><V><T><T><L... | Plays a role in phosphate homeostasis. Mediates phosphate export from the cell . Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules .<BOP> | Q9UBH6 |
Q9ULC6 | PADI1_HUMAN | Protein-arginine deiminase type I | Homo | <M><A><P><K><R><V><V><Q><L><S><L><K><M><P><T><H><A><V><C><V><V><G><V><E><A><H><V><D><I><H><S><D><V><P><K><G><A><N><S><F><R><V><S><G><S><S><G><V><E><V><F><M><V><Y><N><R><T><R><V><K><E><P><I><G><K><A><R><W><P><L><D><T><D><A><D><M><V><V><S><V><G><T><A><S><K><E><L><K><D><F><K><V><R><V><S><Y><F><G><E><Q><E><D><Q><A><L><G><R... | Catalyzes the deimination of arginine residues of proteins.<BOP> | Q9ULC6 |
P48664 | EAA4_HUMAN | Solute carrier family 1 member 6 | Homo | <M><S><S><H><G><N><S><L><F><L><R><E><S><G><Q><R><L><G><R><V><G><W><L><Q><R><L><Q><E><S><L><Q><Q><R><A><L><R><T><R><L><R><L><Q><T><M><T><L><E><H><V><L><R><F><L><R><R><N><A><F><I><L><L><T><V><S><A><V><V><I><G><V><S><L><A><F><A><L><R><P><Y><Q><L><T><Y><R><Q><I><K><Y><F><S><F><P><G><E><L><L><M><R><M><L><Q><M><L><V><L><P><L... | Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate . Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl... | P48664 |
Q96EE3 | SEH1_HUMAN | SEC13-like protein | Homo | <M><F><V><A><R><S><I><A><A><D><H><K><D><L><I><H><D><V><S><F><D><F><H><G><R><R><M><A><T><C><S><S><D><Q><S><V><K><V><W><D><K><S><E><S><G><D><W><H><C><T><A><S><W><K><T><H><S><G><S><V><W><R><V><T><W><A><H><P><E><F><G><Q><V><L><A><S><C><S><F><D><R><T><A><A><V><W><E><E><I><V><G><E><S><N><D><K><L><R><G><Q><S><H><W><V><K><R><T... | As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 .<BO... | Q96EE3 |
Q8NCN4 | RN169_HUMAN | RING-type E3 ubiquitin transferase RNF169 | Homo | <M><A><A><A><G><P><S><T><R><A><S><S><A><A><A><A><A><A><L><S><R><R><G><R><R><G><R><C><D><E><T><A><A><A><K><T><G><A><P><G><P><A><S><G><P><S><L><L><V><L><S><P><P><L><L><Q><P><P><L><P><P><R><P><E><E><S><G><C><A><G><C><L><E><P><P><G><E><A><A><A><L><P><C><G><H><S><L><C><R><G><C><A><Q><R><A><A><D><A><A><G><P><G><C><P><R><C><R... | Probable E3 ubiquitin-protein ligase that acts as a regulator of double-strand breaks (DSBs) repair following DNA damage. Functions in a non-canonical fashion to harness RNF168-mediated protein recruitment to DSB-containing chromatin, thereby contributing to regulation of DSB repair pathway utilization . Once recruited... | Q8NCN4 |
P0DN87 | CGB7_HUMAN | Choriogonadotropin subunit beta 7 | Homo | <M><E><M><F><Q><G><L><L><L><L><L><L><L><S><M><G><G><T><W><A><S><R><E><M><L><R><P><R><C><R><P><I><N><A><T><L><A><V><E><K><E><G><C><P><V><C><I><T><V><N><T><T><I><C><A><G><Y><C><P><T><M><T><R><V><L><Q><G><V><L><P><A><L><P><Q><V><V><C><N><Y><R><D><V><R><F><E><S><I><R><L><P><G><C><P><R><G><V><N><P><V><V><S><Y><A><V><A><L><S... | Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the ... | P0DN87 |
P31358 | CD52_HUMAN | Human epididymis-specific protein 5 | Homo | <M><K><R><F><L><F><L><L><L><T><I><S><L><L><V><M><V><Q><I><Q><T><G><L><S><G><Q><N><D><T><S><Q><T><S><S><P><S><A><S><S><N><I><S><G><G><I><F><L><F><F><V><A><N><A><I><I><H><L><F><C><F><S> | May play a role in carrying and orienting carbohydrate, as well as having a more specific role.<BOP> | P31358 |
A0A0C4DH41 | HV461_HUMAN | Immunoglobulin heavy variable 4-61 | Homo | <M><K><H><L><W><F><F><L><L><L><V><A><A><P><R><W><V><L><S><Q><V><Q><L><Q><E><S><G><P><G><L><V><K><P><S><E><T><L><S><L><T><C><T><V><S><G><G><S><V><S><S><G><S><Y><Y><W><S><W><I><R><Q><P><P><G><K><G><L><E><W><I><G><Y><I><Y><Y><S><G><S><T><N><Y><N><P><S><L><K><S><R><V><T><I><S><V><D><T><S><K><N><Q><F><S><L><K><L><S><S><V><T... | V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | A0A0C4DH41 |
Q9UPG8 | PLAL2_HUMAN | Pleiomorphic adenoma-like protein 2 | Homo | <M><T><T><F><F><T><S><V><P><P><W><I><Q><D><A><K><Q><E><E><E><V><G><W><K><L><V><P><R><P><R><G><R><E><A><E><S><Q><V><K><C><Q><C><E><I><S><G><T><P><F><S><N><G><E><K><L><R><P><H><S><L><P><Q><P><E><Q><R><P><Y><S><C><P><Q><L><H><C><G><K><A><F><A><S><K><Y><K><L><Y><R><H><M><A><T><H><S><A><Q><K><P><H><Q><C><M><Y><C><D><K><M><F... | Shows weak transcriptional activatory activity.<BOP> | Q9UPG8 |
Q86XN6 | ZN761_HUMAN | Zinc finger protein 761 | Homo | <M><A><F><S><Q><G><L><L><T><F><R><D><V><A><I><E><F><S><Q><E><E><W><K><C><L><D><P><A><Q><R><T><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><S><L><D><I><S><S><K><C><T><M><K><E><F><L><S><T><A><Q><G><N><R><E><V><F><H><A><G><T><L><Q><I><H><E><S><H><H><N><G><D><F><C><Y><Q><D><V><D><K><D><I><H><D><Y><E><F><Q><W><Q><E><D><E><R><N... | May be involved in transcriptional regulation.<BOP> | Q86XN6 |
Q96BR9 | ZBT8A_HUMAN | BTB/POZ and zinc-finger domains factor on chromosome 1 | Homo | <M><E><I><S><S><H><Q><S><H><L><L><Q><Q><L><N><E><Q><R><R><Q><D><V><F><C><D><C><S><I><L><V><E><G><K><V><F><K><A><H><R><N><V><L><F><A><S><S><G><Y><F><K><M><L><L><S><Q><N><S><K><E><T><S><Q><P><T><T><A><T><F><Q><A><F><S><P><D><T><F><T><V><I><L><D><F><V><Y><S><G><K><L><S><L><T><G><Q><N><V><I><E><V><M><S><A><A><S><F><L><Q><M... | May be involved in transcriptional regulation.<BOP> | Q96BR9 |
P55957 | BID_HUMAN | p11 BID | Homo | <M><D><C><E><V><N><N><G><S><S><L><R><D><E><C><I><T><N><L><L><V><F><G><F><L><Q><S><C><S><D><N><S><F><R><R><E><L><D><A><L><G><H><E><L><P><V><L><A><P><Q><W><E><G><Y><D><E><L><Q><T><D><G><N><R><S><S><H><S><R><L><G><R><I><E><A><D><S><E><S><Q><E><D><I><I><R><N><I><A><R><H><L><A><Q><V><G><D><S><M><D><R><S><I><P><P><G><L><V><N... | Induces ICE-like proteases and apoptosis.<BOP> | P55957 |
P11168 | GTR2_HUMAN | Glucose transporter type 2, liver | Homo | <M><T><E><D><K><V><T><G><T><L><V><F><T><V><I><T><A><V><L><G><S><F><Q><F><G><Y><D><I><G><V><I><N><A><P><Q><Q><V><I><I><S><H><Y><R><H><V><L><G><V><P><L><D><D><R><K><A><I><N><N><Y><V><I><N><S><T><D><E><L><P><T><I><S><Y><S><M><N><P><K><P><T><P><W><A><E><E><E><T><V><A><A><A><Q><L><I><T><M><L><W><S><L><S><V><S><S><F><A><V><G... | Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose . Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell... | P11168 |
Q8NCE0 | SEN2_HUMAN | tRNA-intron endonuclease Sen2 | Homo | <M><A><E><A><V><F><H><A><P><K><R><K><R><R><V><Y><E><T><Y><E><S><P><L><P><I><P><F><G><Q><D><H><G><P><L><K><E><F><K><I><F><R><A><E><M><I><N><N><N><V><I><V><R><N><A><E><D><I><E><Q><L><Y><G><K><G><Y><F><G><K><G><I><L><S><R><S><R><P><S><F><T><I><S><D><P><K><L><V><A><K><W><K><D><M><K><T><N><M><P><I><I><T><S><K><R><Y><Q><H><S... | Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cy... | Q8NCE0 |
Q96IY4 | CBPB2_HUMAN | Thrombin-activable fibrinolysis inhibitor | Homo | <M><K><L><C><S><L><A><V><L><V><P><I><V><L><F><C><E><Q><H><V><F><A><F><Q><S><G><Q><V><L><A><A><L><P><R><T><S><R><Q><V><Q><V><L><Q><N><L><T><T><T><Y><E><I><V><L><W><Q><P><V><T><A><D><L><I><V><K><K><K><Q><V><H><F><F><V><N><A><S><D><V><D><N><V><K><A><H><L><N><V><S><G><I><P><C><S><V><L><L><A><D><V><E><D><L><I><Q><Q><Q><I><S... | Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.<BOP> | Q96IY4 |
Q96RD0 | OR8B2_HUMAN | Olfactory receptor OR11-309 | Homo | <M><L><A><R><N><N><S><L><V><T><E><F><I><L><A><G><L><T><D><H><P><E><F><R><Q><P><L><F><F><L><F><L><V><I><Y><I><V><T><M><V><G><N><L><G><L><I><T><L><F><G><L><N><S><H><L><H><T><P><M><Y><Y><F><L><F><N><L><S><F><I><D><L><C><Y><S><S><V><F><T><P><K><M><L><M><N><F><V><S><K><K><N><I><I><S><N><V><G><C><M><T><R><L><F><F><F><L><F><F... | Odorant receptor.<BOP> | Q96RD0 |
P49763 | PLGF_HUMAN | Placenta growth factor | Homo | <M><P><V><M><R><L><F><P><C><F><L><Q><L><L><A><G><L><A><L><P><A><V><P><P><Q><Q><W><A><L><S><A><G><N><G><S><S><E><V><E><V><V><P><F><Q><E><V><W><G><R><S><Y><C><R><A><L><E><R><L><V><D><V><V><S><E><Y><P><S><E><V><E><H><M><F><S><P><S><C><V><S><L><L><R><C><T><G><C><C><G><D><E><N><L><H><C><V><P><V><E><T><A><N><V><T><M><Q><L><L... | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.<BOP> | P49763 |
P46063 | RECQ1_HUMAN | RecQ protein-like 1 | Homo | <M><A><S><V><S><A><L><T><E><E><L><D><S><I><T><S><E><L><H><A><V><E><I><Q><I><Q><E><L><T><E><R><Q><Q><E><L><I><Q><K><K><K><V><L><T><K><K><I><K><Q><C><L><E><D><S><D><A><G><A><S><N><E><Y><D><S><S><P><A><A><W><N><K><E><D><F><P><W><S><G><K><V><K><D><I><L><Q><N><V><F><K><L><E><K><F><R><P><L><Q><L><E><T><I><N><V><T><M><A><G><K... | DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.<BOP> | P46063 |
Q9H0R5 | GBP3_HUMAN | Guanine nucleotide-binding protein 3 | Homo | <M><A><P><E><I><H><M><T><G><P><M><C><L><I><E><N><T><N><G><E><L><V><A><N><P><E><A><L><K><I><L><S><A><I><T><Q><P><V><V><V><V><A><I><V><G><L><Y><R><T><G><K><S><Y><L><M><N><K><L><A><G><K><N><K><G><F><S><L><G><S><T><V><K><S><H><T><K><G><I><W><M><W><C><V><P><H><P><K><K><P><E><H><T><L><V><L><L><D><T><E><G><L><G><D><V><K><K><G... | Exhibits antiviral activity against influenza virus.<BOP> | Q9H0R5 |
Q9HBI0 | PARVG_HUMAN | Gamma-parvin | Homo | <M><E><P><E><F><L><Y><D><L><L><Q><L><P><K><G><V><E><P><P><A><E><E><E><L><S><K><G><G><K><K><K><Y><L><P><P><T><S><R><K><D><P><K><F><E><E><L><Q><K><V><L><M><E><W><I><N><A><T><L><L><P><E><H><I><V><V><R><S><L><E><E><D><M><F><D><G><L><I><L><H><H><L><F><Q><R><L><A><A><L><K><L><E><A><E><D><I><A><L><T><A><T><S><Q><K><H><K><L><T... | Probably plays a role in the regulation of cell adhesion and cytoskeleton organization.<BOP> | Q9HBI0 |
Q9BPX1 | DHB14_HUMAN | Short chain dehydrogenase/reductase family 47C member 1 | Homo | <M><A><T><G><T><R><Y><A><G><K><V><V><V><V><T><G><G><G><R><G><I><G><A><G><I><V><R><A><F><V><N><S><G><A><R><V><V><I><C><D><K><D><E><S><G><G><R><A><L><E><Q><E><L><P><G><A><V><F><I><L><C><D><V><T><Q><E><D><D><V><K><T><L><V><S><E><T><I><R><R><F><G><R><L><D><C><V><V><N><N><A><G><H><H><P><P><P><Q><R><P><E><E><T><S><A><Q><G><F... | Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).<BOP> | Q9BPX1 |
Q9H4A9 | DPEP2_HUMAN | Dipeptidase 2 | Homo | <M><Q><P><S><G><L><E><G><P><G><T><F><G><R><W><P><L><L><S><L><L><L><L><L><L><L><L><Q><P><V><T><C><A><Y><T><T><P><G><P><P><R><A><L><T><T><L><G><A><P><R><A><H><T><M><P><G><T><Y><A><P><S><T><T><L><S><S><P><S><T><Q><G><L><Q><E><Q><A><R><A><L><M><R><D><F><P><L><V><D><G><H><N><D><L><P><L><V><L><R><Q><V><Y><Q><K><G><L><Q><D><V... | Independently of its dipeptidase activity can also modulate macrophage inflammatory response by acting as a regulator of NF-kappaB inflammatory signaling pathway.<BOP> | Q9H4A9 |
Q96EY4 | TMA16_HUMAN | Translation machinery-associated protein 16 | Homo | <M><P><K><A><P><K><G><K><S><A><G><R><E><K><K><V><I><H><P><Y><S><R><K><A><A><Q><I><T><R><E><A><H><K><Q><E><K><K><E><K><L><K><N><E><K><A><L><R><L><N><L><V><G><E><K><L><Q><W><F><Q><N><H><L><D><P><Q><K><K><R><Y><S><K><K><D><A><C><E><L><I><E><R><Y><L><N><R><F><S><S><E><L><E><Q><I><E><L><H><N><S><I><R><D><R><Q><G><R><R><H><C... | Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.<BOP> | Q96EY4 |
Q9UQC2 | GAB2_HUMAN | pp100 | Homo | <M><S><G><G><G><D><V><V><C><T><G><W><L><R><K><S><P><P><E><K><K><L><R><R><Y><A><W><K><K><R><W><F><I><L><R><S><G><R><M><S><G><D><P><D><V><L><E><Y><Y><K><N><D><H><S><K><K><P><L><R><I><I><N><L><N><F><C><E><Q><V><D><A><G><L><T><F><N><K><K><E><L><Q><D><S><F><V><F><D><I><K><T><S><E><R><T><F><Y><L><V><A><E><T><E><E><D><M><N><K... | Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells acti... | Q9UQC2 |
P09016 | HXD4_HUMAN | Homeobox protein Hox-5.1 | Homo | <M><V><M><S><S><Y><M><V><N><S><K><Y><V><D><P><K><F><P><P><C><E><E><Y><L><Q><G><G><Y><L><G><E><Q><G><A><D><Y><Y><G><G><G><A><Q><G><A><D><F><Q><P><P><G><L><Y><P><R><P><D><F><G><E><Q><P><F><G><G><S><G><P><G><P><G><S><A><L><P><A><R><G><H><G><Q><E><P><G><G><P><G><G><H><Y><A><A><P><G><E><P><C><P><A><P><P><A><P><P><P><A><P><L... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | P09016 |
Q9BXI2 | ORNT2_HUMAN | Solute carrier family 25 member 2 | Homo | <M><K><S><G><P><G><I><Q><A><A><I><D><L><T><A><G><A><A><G><G><T><A><C><V><L><T><G><Q><P><F><D><T><I><K><V><K><M><Q><T><F><P><D><L><Y><K><G><L><T><D><C><F><L><K><T><Y><A><Q><V><G><L><R><G><F><Y><K><G><T><G><P><A><L><M><A><Y><V><A><E><N><S><V><L><F><M><C><Y><G><F><C><Q><Q><F><V><R><K><V><A><G><M><D><K><Q><A><K><L><S><D><L... | Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.<BOP> | Q9BXI2 |
A8MTL9 | HMSD_HUMAN | Minor histocompatibility serpin domain-containing protein | Homo | <M><S><I><S><S><A><L><A><M><V><F><M><G><A><K><G><N><T><A><A><Q><M><S><Q><A><L><C><F><S><K><I><G><G><E><D><G><D><I><H><R><G><F><Q><S><L><L><V><A><I><N><R><T><D><T><E><Y><V><L><R><T><A><N><G><L><F><G><E><K><S><Y><D><F><L><T><G><F><T><D><S><C><G><K><F><Y><Q><A><T><I><K><Q><L><D><F><V><N><D><T><E><K><S><T><T><R><V><N><S><W... | Putative serine protease inhibitor.<BOP> | A8MTL9 |
Q9Y235 | ABEC2_HUMAN | mRNA(cytosine(6666)) deaminase 2 | Homo | <M><A><Q><K><E><E><A><A><V><A><T><E><A><A><S><Q><N><G><E><D><L><E><N><L><D><D><P><E><K><L><K><E><L><I><E><L><P><P><F><E><I><V><T><G><E><R><L><P><A><N><F><F><K><F><Q><F><R><N><V><E><Y><S><S><G><R><N><K><T><F><L><C><Y><V><V><E><A><Q><G><K><G><G><Q><V><Q><A><S><R><G><Y><L><E><D><E><H><A><A><A><H><A><E><E><A><F><F><N><T><I... | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.<BOP> | Q9Y235 |
Q9NVA1 | UQCC1_HUMAN | Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog | Homo | <M><A><L><L><V><R><V><L><R><N><Q><T><S><I><S><Q><W><V><P><V><C><S><R><L><I><P><V><S><P><T><Q><G><Q><G><D><R><A><L><S><R><T><S><Q><W><P><Q><M><S><Q><S><R><A><C><G><G><S><E><Q><I><P><G><I><D><I><Q><L><N><R><K><Y><H><T><T><R><K><L><S><T><T><K><D><S><P><Q><P><V><E><E><K><V><G><A><F><T><K><I><I><E><A><M><G><F><T><G><P><L><K... | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex). Involved in cytochrome b translation and/or stability.<BOP> | Q9NVA1 |
Q8N4A0 | GALT4_HUMAN | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4 | Homo | <M><A><V><R><W><T><W><A><G><K><S><C><L><L><L><A><F><L><T><V><A><Y><I><F><V><E><L><L><V><S><T><F><H><A><S><A><G><A><G><R><A><R><E><L><G><S><R><R><L><S><D><L><Q><K><N><T><E><D><L><S><R><P><L><Y><K><K><P><P><A><D><S><R><A><L><G><E><W><G><K><A><S><K><L><Q><L><N><E><D><E><L><K><Q><Q><E><E><L><I><E><R><Y><A><I><N><I><Y><L><S... | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG.<BOP> | Q8N4A0 |
P49354 | FNTA_HUMAN | Type I protein geranyl-geranyltransferase subunit alpha | Homo | <M><A><A><T><E><G><V><G><E><A><A><Q><G><G><E><P><G><Q><P><A><Q><P><P><P><Q><P><H><P><P><P><P><Q><Q><Q><H><K><E><E><M><A><A><E><A><G><E><A><V><A><S><P><M><D><D><G><F><V><S><L><D><S><P><S><Y><V><L><Y><R><D><R><A><E><W><A><D><I><D><P><V><P><Q><N><D><G><P><N><P><V><V><Q><I><I><Y><S><D><K><F><R><D><V><Y><D><Y><F><R><A><V><L... | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-alip... | P49354 |
P16083 | NQO2_HUMAN | Quinone reductase 2 | Homo | <M><A><G><K><K><V><L><I><V><Y><A><H><Q><E><P><K><S><F><N><G><S><L><K><N><V><A><V><D><E><L><S><R><Q><G><C><T><V><T><V><S><D><L><Y><A><M><N><L><E><P><R><A><T><D><K><D><I><T><G><T><L><S><N><P><E><V><F><N><Y><G><V><E><T><H><E><A><Y><K><Q><R><S><L><A><S><D><I><T><D><E><Q><K><K><V><R><E><A><D><L><V><I><F><Q><F><P><L><Y><W><F... | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<BOP> | P16083 |
P0CH99 | Z705D_HUMAN | Zinc finger protein 705D | Homo | <M><H><S><L><E><K><V><T><F><E><D><V><A><I><D><F><T><Q><E><E><W><D><M><M><D><T><S><K><R><K><L><Y><R><D><V><M><L><E><N><I><S><H><L><V><S><L><G><Y><Q><I><S><K><S><Y><I><I><L><Q><L><E><Q><G><K><E><L><W><R><E><G><R><V><F><L><Q><D><Q><N><P><D><R><E><S><A><L><K><K><K><H><M><I><S><M><H><P><I><I><R><K><D><A><S><T><S><M><T><M><E... | May be involved in transcriptional regulation.<BOP> | P0CH99 |
P78537 | BL1S1_HUMAN | Protein RT14 | Homo | <M><A><P><G><S><R><G><E><R><S><S><F><R><S><R><R><G><P><G><V><P><S><P><Q><P><D><V><T><M><L><S><R><L><L><K><E><H><Q><A><K><Q><N><E><R><K><E><L><Q><E><K><R><R><R><E><A><I><T><A><A><T><C><L><T><E><A><L><V><D><H><L><N><V><G><V><A><Q><A><Y><M><N><Q><R><K><L><D><H><E><V><K><T><L><Q><V><Q><A><A><Q><F><A><K><Q><T><G><Q><W><I><G... | May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.<BOP> | P78537 |
Q9UJ42 | GP160_HUMAN | G-protein coupled receptor GPCR1 | Homo | <M><T><A><L><S><S><E><N><C><S><F><Q><Y><Q><L><R><Q><T><N><Q><P><L><D><V><N><Y><L><L><F><L><I><I><L><G><K><I><L><L><N><I><L><T><L><G><M><R><R><K><N><T><C><Q><N><F><M><E><Y><F><C><I><S><L><A><F><V><D><L><L><L><L><V><N><I><S><I><I><L><Y><F><R><D><F><V><L><L><S><I><R><F><T><K><Y><H><I><C><L><F><T><Q><I><I><S><F><T><Y><G><F... | Orphan receptor.<BOP> | Q9UJ42 |
Q9Y3B8 | ORN_HUMAN | Small fragment nuclease | Homo | <M><L><G><G><S><L><G><S><R><L><L><R><G><V><G><G><S><H><G><R><F><G><A><R><G><V><R><E><G><G><A><A><M><A><A><G><E><S><M><A><Q><R><M><V><W><V><D><L><E><M><T><G><L><D><I><E><K><D><Q><I><I><E><M><A><C><L><I><T><D><S><D><L><N><I><L><A><E><G><P><N><L><I><I><K><Q><P><D><E><L><L><D><S><M><S><D><W><C><K><E><H><H><G><K><S><G><L><T... | 3'-to-5'exoribonuclease that preferentially degrades DNA and RNA oligonucleotides composed of only two nucleotides.<BOP> | Q9Y3B8 |
P0C623 | OR4Q2_HUMAN | olfactory receptor OR14-21 | Homo | <M><D><K><N><Q><T><E><V><M><R><E><F><F><L><S><G><F><S><Q><T><P><S><I><E><A><G><L><F><V><L><F><L><F><F><Y><M><S><I><W><V><G><N><V><L><I><M><V><T><V><A><S><D><K><Y><L><N><S><S><P><M><Y><F><L><L><G><N><L><S><F><L><D><L><C><Y><S><T><V><T><T><P><K><L><L><A><D><F><F><N><H><E><K><L><I><S><Y><D><Q><C><I><V><Q><L><F><F><L><H><F... | Odorant receptor.<BOP> | P0C623 |
P10153 | RNAS2_HUMAN | Ribonuclease US | Homo | <M><V><P><K><L><F><T><S><Q><I><C><L><L><L><L><L><G><L><L><A><V><E><G><S><L><H><V><K><P><P><Q><F><T><W><A><Q><W><F><E><T><Q><H><I><N><M><T><S><Q><Q><C><T><N><A><M><Q><V><I><N><N><Y><Q><R><R><C><K><N><Q><N><T><F><L><L><T><T><F><A><N><V><V><N><V><C><G><N><P><N><M><T><C><P><S><N><K><T><R><K><N><C><H><H><S><G><S><Q><V><P><L... | This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.<BOP> | P10153 |
Q8N815 | CNTD1_HUMAN | Cyclin N-terminal domain-containing protein 1 | Homo | <M><D><G><P><M><R><P><R><S><A><S><L><V><D><F><Q><F><G><V><V><A><T><E><T><I><E><D><A><L><L><H><L><A><Q><Q><N><E><Q><A><V><R><E><A><S><G><R><L><G><R><F><R><E><P><Q><I><V><E><F><V><F><L><L><S><E><Q><W><C><L><E><K><S><V><S><Y><Q><A><V><E><I><L><E><R><F><M><V><K><Q><A><E><N><I><C><R><Q><A><T><I><Q><P><R><D><N><K><R><E><S><Q... | Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimulates crossover formation through the interactions with RFC3 and RFC4 and si... | Q8N815 |
Q6R6M4 | U17L2_HUMAN | Ubiquitin-specific-processing protease 17-like protein 2 | Homo | <M><E><D><D><S><L><Y><L><G><G><E><W><Q><F><N><H><F><S><K><L><T><S><S><R><P><D><A><A><F><A><E><I><Q><R><T><S><L><P><E><K><S><P><L><S><S><E><A><R><V><D><L><C><D><D><L><A><P><V><A><R><Q><L><A><P><R><K><K><L><P><L><S><S><R><R><P><A><A><V><G><A><G><L><Q><N><M><G><N><T><C><Y><E><N><A><S><L><Q><C><L><T><Y><T><P><P><L><A><N><Y... | Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Regulates cell proliferation by deubiquitinating and inhibiting RCE1 thereby controlling the small GTPases NRAS and HRAS localization and activation. In parallel, mediates deubiquitination of CDC25... | Q6R6M4 |
Q01726 | MSHR_HUMAN | null | Homo | <M><A><V><Q><G><S><Q><R><R><L><L><G><S><L><N><S><T><P><T><A><I><P><Q><L><G><L><A><A><N><Q><T><G><A><R><C><L><E><V><S><I><S><D><G><L><F><L><S><L><G><L><V><S><L><V><E><N><A><L><V><V><A><T><I><A><K><N><R><N><L><H><S><P><M><Y><C><F><I><C><C><L><A><L><S><D><L><L><V><S><G><S><N><V><L><E><T><A><V><I><L><L><L><E><A><G><A><L><V... | Receptor for MSH (alpha, beta and gamma) and ACTH . The activity of this receptor is mediated by G proteins which activate adenylate cyclase . Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes .<BOP> | Q01726 |
O95169 | NDUB8_HUMAN | NADH-ubiquinone oxidoreductase ASHI subunit | Homo | <M><A><V><A><R><A><G><V><L><G><V><Q><W><L><Q><R><A><S><R><N><V><M><P><L><G><A><R><T><A><S><H><M><T><K><D><M><F><P><G><P><Y><P><R><T><P><E><E><R><A><A><A><A><K><K><Y><N><M><R><V><E><D><Y><E><P><Y><P><D><D><G><M><G><Y><G><D><Y><P><K><L><P><D><R><S><Q><H><E><R><D><P><W><Y><S><W><D><Q><P><G><L><R><L><N><W><G><E><P><M><H><W... | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP> | O95169 |
Q96PL5 | ERMAP_HUMAN | Scianna blood group antigen | Homo | <M><E><M><A><S><S><A><G><S><W><L><S><G><C><L><I><P><L><V><F><L><R><L><S><V><H><V><S><G><H><A><G><D><A><G><K><F><H><V><A><L><L><G><G><T><A><E><L><L><C><P><L><S><L><W><P><G><T><V><P><K><E><V><R><W><L><R><S><P><F><P><Q><R><S><Q><A><V><H><I><F><R><D><G><K><D><Q><D><E><D><L><M><P><E><Y><K><G><R><T><V><L><V><R><D><A><Q><E><G... | Possible role as a cell-adhesion or receptor molecule of erythroid cells.<BOP> | Q96PL5 |
Q9GZK3 | OR2B2_HUMAN | Olfactory receptor 6-1 | Homo | <M><N><W><V><N><K><S><V><P><Q><E><F><I><L><L><V><F><S><D><Q><P><W><L><E><I><P><P><F><V><M><F><L><F><S><Y><I><L><T><I><F><G><N><L><T><I><I><L><V><S><H><V><D><F><K><L><H><T><P><M><Y><F><F><L><S><N><L><S><L><L><D><L><C><Y><T><T><S><T><V><P><Q><M><L><V><N><I><C><N><T><R><K><V><I><S><Y><G><G><C><V><A><Q><L><F><I><F><L><A><L... | Odorant receptor.<BOP> | Q9GZK3 |
Q02962 | PAX2_HUMAN | Paired box protein Pax-2 | Homo | <M><D><M><H><C><K><A><D><P><F><S><A><M><H><P><G><H><G><G><V><N><Q><L><G><G><V><F><V><N><G><R><P><L><P><D><V><V><R><Q><R><I><V><E><L><A><H><Q><G><V><R><P><C><D><I><S><R><Q><L><R><V><S><H><G><C><V><S><K><I><L><G><R><Y><Y><E><T><G><S><I><K><P><G><V><I><G><G><S><K><P><K><V><A><T><P><K><V><V><D><K><I><A><E><Y><K><R><Q><N><P... | Transcription factor that may have a role in kidney cell differentiation . Has a critical role in the development of the urogenital tract, the eyes, and the CNS.<BOP> | Q02962 |
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