accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
B0SC03 | TRUA_LEPBA | tRNA-uridine isomerase I | Leptospira | <M><P><N><Y><A><L><L><V><E><Y><D><G><T><H><F><N><G><W><Q><K><Q><K><N><L><P><T><V><Q><S><S><I><E><S><A><L><G><I><I><L><R><R><N><P><A><S><R><L><S><V><A><G><R><T><D><T><G><V><H><A><L><G><M><V><C><N><F><K><T><E><H><P><I><P><N><F><H><K><L><L><V><S><L><N><A><L><T><P><T><G><V><S><V><K><N><V><V><E><V><P><S><D><F><H><A><R><F><S... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | B0SC03 |
P0DL16 | CRVP_NAJMO | Cysteine-rich venom protein mossambin | Naja | <N><V><D><F><N><S><E><S><T><R><R><K><K><K><Q><N><E><I><V><D><L><H><N><S><L><R><R><T><V><N> | Inhibits calcium-activated potassium channels (KCa), voltage-gated potassium channel (Kv), and the calcium release channel/ryanodine receptor (RyR).<BOP> | P0DL16 |
B7JZP4 | ACCA_RIPO1 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Rippkaea orientalis | <M><S><K><N><E><R><R><T><F><L><L><D><F><E><K><P><L><W><E><L><E><A><R><I><N><Q><I><R><E><L><A><E><E><N><N><V><D><V><S><E><Q><I><A><Q><L><E><R><R><A><E><E><L><R><Q><E><I><F><S><T><L><T><P><S><Q><R><L><Q><L><A><R><H><P><R><R><P><S><T><L><D><Y><I><Q><A><I><A><D><E><W><F><E><L><H><G><D><R><G><G><Y><D><D><P><A><L><V><G><G><V... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP> | B7JZP4 |
Q3ZXS0 | NUOB_DEHMC | NDH-1 subunit B | Dehalococcoides | <M><E><L><N><F><E><K><P><L><S><L><L><T><L><D><E><I><D><Q><Q><E><G><G><V><I><Q><S><F><R><T><G><H><T><S><P><Y><P><D><P><A><D><W><L><N><G><E><E><P><P><P><G><V><F><I><T><S><V><E><K><V><L><N><W><S><R><H><Y><S><L><W><P><V><M><F><G><L><A><C><C><A><I><E><M><M><C><M><A><A><S><R><W><D><L><A><R><F><G><M><D><I><F><R><A><S><P><R><Q... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q3ZXS0 |
Q256C2 | CLPP1_CHLFF | Endopeptidase Clp 1 | Chlamydia | <M><T><L><V><P><Y><V><V><E><D><T><G><R><G><E><R><A><M><D><I><Y><S><R><L><L><K><D><R><I><V><M><I><G><Q><E><I><T><E><P><L><A><N><T><V><I><A><Q><L><L><F><L><M><S><E><D><P><Q><K><D><I><K><V><F><I><N><S><P><G><G><Y><I><T><A><G><L><A><I><Y><D><T><I><R><F><L><G><C><D><V><N><T><Y><C><I><G><Q><A><A><S><M><G><A><L><L><L><S><A><G... | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP> | Q256C2 |
Q5FA58 | RIMM_NEIG1 | Ribosome maturation factor RimM | Neisseria | <M><T><D><T><Q><N><R><V><A><M><G><Y><I><K><G><V><F><G><I><K><G><W><L><K><I><A><A><N><T><E><Y><S><D><S><L><L><D><Y><P><E><W><H><L><A><K><D><G><K><T><V><S><V><T><L><E><A><G><K><V><V><N><G><E><L><Q><V><K><F><E><G><I><D><D><R><D><S><A><F><S><L><R><G><Y><T><I><E><I><P><R><E><A><F><A><P><T><E><E><D><E><Y><Y><W><A><D><L><V><G... | An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma... | Q5FA58 |
B8DZY2 | RL25_DICTD | General stress protein CTC | Dictyoglomus | <M><E><I><T><E><I><K><V><K><K><R><D><K><I><G><K><Q><F><A><K><K><Y><R><R><S><N><L><I><P><G><V><V><Y><G><A><H><L><K><E><N><I><H><I><L><V><E><K><K><D><L><W><S><L><I><K><K><G><H><A><K><E><Q><H><L><L><R><L><I><I><E><N><G><E><N><T><I><T><E><N><A><I><L><Q><D><L><Q><I><D><P><I><K><D><E><F><L><H><V><D><F><H><A><I><T><L><E><E><L... | This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP> | B8DZY2 |
Q8BJ03 | COX15_MOUSE | Cytochrome c oxidase assembly protein COX15 homolog | Mus | <M><Q><R><L><L><L><P><S><L><R><A><L><T><G><S><R><N><V><G><L><L><V><P><R><V><A><S><R><T><Q><C><G><S><S><C><G><S><Q><R><P><L><R><P><G><Q><Y><S><T><I><T><E><V><A><L><Q><S><G><K><G><T><V><S><L><P><S><R><A><A><E><R><A><V><G><R><W><L><L><V><C><S><G><T><V><A><G><A><V><I><L><G><G><V><T><R><L><T><E><S><G><L><S><M><V><D><W><H><L... | May be involved in the biosynthesis of heme A.<BOP> | Q8BJ03 |
C1KVD5 | NADD_LISMC | Nicotinate mononucleotide adenylyltransferase | Listeria | <M><K><H><K><V><G><I><L><G><G><T><F><D><P><P><H><L><A><H><L><R><M><A><E><E><A><K><K><Q><L><G><L><E><K><I><L><F><L><P><N><K><I><P><P><H><K><H><I><S><G><M><A><S><S><D><E><R><V><E><M><L><Q><L><M><I><E><G><I><D><S><F><E><I><D><T><R><E><L><M><R><A><G><K><S><Y><T><Y><D><T><M><R><D><M><I><S><E><Q><P><D><T><D><F><Y><F><I><I><G... | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP> | C1KVD5 |
Q92AH4 | PYRK_LISIN | Dihydroorotate oxidase B, electron transfer subunit | Listeria | <M><L><Q><T><E><M><K><V><I><Q><Q><T><E><I><A><D><K><V><Y><E><L><I><L><S><G><E><C><V><A><D><M><S><P><G><Q><F><L><M><L><K><P><S><R><S><D><L><L><M><R><R><P><I><S><I><C><S><Y><D><K><T><A><K><T><C><I><L><L><Y><R><V><E><G><D><G><T><K><D><F><S><S><L><S><K><G><D><S><I><D><V><L><G><P><L><G><K><G><F><D><L><N><T><I><P><A><P><K><T... | Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).<BOP> | Q92AH4 |
P58182 | O12D2_HUMAN | Olfactory receptor OR6-28 | Homo | <M><L><N><T><T><S><V><T><E><F><L><L><L><G><V><T><D><I><Q><E><L><Q><P><F><L><F><V><V><F><L><T><I><Y><F><I><S><V><T><G><N><G><A><V><L><M><I><V><I><S><D><P><R><L><H><S><L><M><Y><F><F><L><G><N><L><S><Y><L><D><I><C><Y><S><T><V><T><L><P><K><M><L><Q><N><F><L><S><T><H><K><A><I><S><F><L><G><C><I><S><Q><L><H><F><F><H><S><L><G><S... | Odorant receptor.<BOP> | P58182 |
Q22RG7 | H34_TETTS | Minor histone H3 variant | Tetrahymena | <M><A><R><T><K><Q><T><A><R><K><S><T><S><I><K><A><P><R><K><Q><L><A><A><K><A><A><R><K><S><A><P><I><S><G><G><I><K><K><P><H><K><F><R><P><G><T><V><A><L><R><E><I><R><K><Y><Q><K><T><T><D><L><L><I><R><K><L><P><F><Q><R><L><V><R><D><I><A><M><E><M><K><S><D><I><R><F><Q><S><Q><A><I><L><A><L><Q><E><A><A><E><A><Y><L><V><G><L><F><E><D... | Macronuclear replacement variant which replaces conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replicati... | Q22RG7 |
B2JFK6 | ACPS_PARP8 | 4'-phosphopantetheinyl transferase AcpS | Paraburkholderia | <M><A><I><Y><G><I><G><T><D><I><V><Q><V><S><R><V><A><A><V><M><Q><R><T><N><G><R><F><A><E><K><V><L><G><P><D><E><L><R><V><Y><H><A><R><H><A><R><S><Q><A><R><G><L><A><F><L><A><T><R><F><S><V><K><E><A><F><S><K><A><I><G><L><G><M><R><W><P><M><T><W><R><A><L><Q><T><L><N><E><P><S><G><R><P><T><C><V><A><S><G><E><L><A><D><W><L><A><E><R... | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP> | B2JFK6 |
Q884C8 | SYE_PSESM | Glutamyl-tRNA synthetase | Pseudomonas | <M><T><T><V><R><T><R><I><A><P><S><P><T><G><D><P><H><V><G><T><A><Y><I><A><L><F><N><Y><C><F><A><K><Q><H><G><G><E><F><I><L><R><I><E><D><T><D><Q><L><R><S><T><R><E><S><E><Q><Q><I><F><D><A><L><R><W><L><G><I><E><W><S><E><G><P><D><V><G><G><P><H><G><P><Y><R><Q><S><E><R><G><D><I><Y><Q><K><Y><A><Q><Q><L><V><E><L><G><H><A><F><P><C... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | Q884C8 |
C0QWN8 | ACKA_BRAHW | Acetokinase | Brachyspira | <M><N><V><L><V><I><N><S><G><S><S><S><I><K><Y><Q><L><F><A><M><P><E><A><K><V><L><A><K><G><L><L><E><K><I><G><E><E><I><S><A><L><K><H><T><A><V><E><K><G><K><E><K><K><I><E><Q><K><V><A><D><H><K><A><G><M><S><L><I><F><S><L><L><T><D><K><E><V><G><V><I><A><D><M><N><E><I><S><A><V><G><H><R><V><V><H><G><G><E><A><F><N><K><S><I><L><I><T... | Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.<BOP> | C0QWN8 |
Q32I48 | UVRB_SHIDS | Excinuclease ABC subunit B | Shigella | <M><S><K><P><F><K><L><N><S><A><F><K><P><S><G><D><Q><P><E><A><I><R><R><L><E><E><G><L><E><D><G><L><A><H><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><I><A><N><V><I><A><D><L><Q><R><P><T><M><V><L><A><P><N><K><T><L><A><A><Q><L><Y><G><E><M><K><E><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><S><S><D><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q32I48 |
Q9V4I1 | CP9B2_DROME | CYPIXB2 | Sophophora | <M><A><L><I><E><I><C><L><A><L><V><V><I><G><Y><L><I><Y><K><W><S><T><A><T><F><K><T><F><E><E><R><K><L><Y><F><E><K><P><Y><P><F><V><G><N><M><A><A><A><A><L><Q><K><S><S><F><Q><R><Q><L><T><E><F><Y><E><R><T><R><Q><H><K><L><V><G><F><F><N><M><R><T><P><M><I><T><L><N><D><P><E><L><I><K><K><V><C><V><K><D><F><D><H><F><P><N><H><Q><P><F... | May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.<BOP> | Q9V4I1 |
Q981J9 | CH605_RHILO | Chaperonin-60 5 | Mesorhizobium | <M><A><A><K><D><V><K><F><S><R><D><A><R><E><R><M><L><R><G><V><N><I><L><A><D><A><V><K><V><T><L><G><P><K><G><R><N><V><V><I><D><K><S><F><G><A><P><R><I><T><K><D><G><V><T><V><A><K><E><I><E><L><E><D><K><F><E><N><M><G><A><Q><M><V><R><E><V><A><S><K><T><N><D><I><A><G><D><G><T><T><T><A><T><V><L><A><Q><S><I><V><Q><E><G><H><K><A><V... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q981J9 |
Q9MUS0 | PSBK_MESVI | Photosystem II reaction center protein K | Mesostigma | <M><N><I><G><F><D><M><I><L><A><K><L><P><E><A><Y><A><M><F><D><P><L><V><D><V><L><P><V><I><P><L><L><F><L><L><L><A><F><V><W><Q><A><S><V><S><F><R> | One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a... | Q9MUS0 |
P05630 | ATPD_BOVIN | F-ATPase delta subunit | Bos | <M><L><P><S><A><L><L><R><R><P><G><L><G><R><L><V><R><Q><V><R><L><Y><A><E><A><A><A><A><Q><A><P><A><A><G><P><G><Q><M><S><F><T><F><A><S><P><T><Q><V><F><F><N><S><A><N><V><R><Q><V><D><V><P><T><Q><T><G><A><F><G><I><L><A><A><H><V><P><T><L><Q><V><L><R><P><G><L><V><V><V><H><A><E><D><G><T><T><S><K><Y><F><V><S><S><G><S><V><T><V><N... | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca... | P05630 |
Q165E3 | GLGC_ROSDO | ADP-glucose synthase | Roseobacter | <M><N><R><E><E><Q><R><L><A><Q><Q><T><M><A><F><V><L><A><G><G><R><G><S><R><L><Y><E><L><T><D><R><R><A><K><P><A><M><Y><F><G><G><K><S><R><I><I><D><F><P><L><S><N><A><V><N><S><G><I><R><R><I><G><V><A><T><Q><Y><K><A><H><S><L><I><R><H><L><Q><R><G><W><S><F><F><R><A><E><R><N><E><S><L><D><I><L><P><A><S><Q><Q><M><N><D><E><N><W><Y><K... | Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.<BOP> | Q165E3 |
B1Y222 | MNMC_LEPCP | FAD-dependent cmnm(5)s(2)U34 oxidoreductase | Leptothrix | <M><R><R><S><N><P><I><T><P><A><R><L><G><R><S><A><E><G><L><P><F><S><E><D><F><G><A><P><Y><H><P><S><A><G><A><L><A><Q><A><E><Q><V><F><L><R><G><T><D><L><P><A><R><W><A><G><Q><A><R><H><V><I><L><E><T><G><F><G><L><G><H><N><F><L><A><T><W><A><A><W><R><R><D><P><R><R><C><E><R><L><V><Y><L><A><I><D><K><H><P><P><A><P><A><D><L><A><D><V... | Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s... | B1Y222 |
Q1D5J5 | NHAA1_MYXXD | Sodium/proton antiporter NhaA 1 | Myxococcus | <M><A><Q><T><P><P><T><S><E><A><R><P><R><P><P><V><P><T><L><F><R><V><A><L><A><P><I><Q><A><F><F><R><L><E><A><A><S><G><I><L><L><A><L><C><A><V><A><A><M><V><W><A><N><S><P><W><A><A><T><Y><S><A><V><F><D><A><R><M><T><V><G><L><A><G><V><H><A><G><F><T><I><R><E><F><I><N><D><G><L><M><T><L><F><F><F><V><V><G><M><E><I><K><R><E><L><S><S... | Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.<BOP> | Q1D5J5 |
Q9FJ74 | WAXS3_ARATH | Wax synthase 3 | Arabidopsis | <M><E><E><E><L><K><N><F><I><K><L><W><I><S><A><I><I><S><I><S><Y><C><Y><Y><L><S><T><G><I><K><A><G><V><F><R><L><L><S><V><L><P><V><C><A><L><F><L><V><F><P><L><F><F><S><Y><V><H><F><S><G><C><M><A><F><F><L><S><W><L><A><N><F><K><L><I><L><F><S><F><D><Q><G><P><L><S><P><L><P><R><T><L><S><R><F><I><C><I><T><C><F><P><I><K><P><Q><Q><N... | Catalyzes the final step in the synthesis of long-chain linear esters (waxes).<BOP> | Q9FJ74 |
P12018 | VPREB_HUMAN | V(pre)B protein | Homo | <M><S><W><A><P><V><L><L><M><L><F><V><Y><C><T><G><C><G><P><Q><P><V><L><H><Q><P><P><A><M><S><S><A><L><G><T><T><I><R><L><T><C><T><L><R><N><D><H><D><I><G><V><Y><S><V><Y><W><Y><Q><Q><R><P><G><H><P><P><R><F><L><L><R><Y><F><S><Q><S><D><K><S><Q><G><P><Q><V><P><P><R><F><S><G><S><K><D><V><A><R><N><R><G><Y><L><S><I><S><E><L><Q><P... | Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B-cell differentiation.<BOP> | P12018 |
A2SPS3 | COFD_METLZ | 2-phospho-L-lactate transferase | Methanocorpusculum | <M><I><T><V><F><S><G><G><T><G><T><P><K><L><I><R><G><L><R><Q><I><L><H><D><H><E><I><T><V><V><V><N><T><A><E><D><L><W><M><S><G><L><Y><V><S><P><D><I><D><T><V><Q><Y><L><F><S><G><L><L><N><T><D><S><W><W><G><I><R><G><D><S><F><E><T><F><H><A><M><E><K><L><G><Y><T><E><L><L><P><L><G><D><K><D><R><A><T><N><I><A><R><A><E><F><L><R><Q><G... | Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.<BOP> | A2SPS3 |
Q4JBV4 | LIPA_SULAC | Sulfur insertion protein LipA | Sulfolobus | <M><K><S><E><V><V><V><R><I><N><E><N><F><K><K><L><S><R><I><V><S><E><K><G><I><S><T><V><C><E><E><A><L><C><P><N><I><M><E><C><W><G><S><G><T><A><T><F><M><I><M><G><D><I><C><T><R><G><C><R><F><C><Y><V><K><K><G><K><P><V><L><L><D><H><E><E><P><I><K><V><A><E><A><V><R><E><M><G><L><D><Y><V><V><I><T><S><V><D><R><D><D><L><A><D><G><G><A... | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP> | Q4JBV4 |
B1KZM3 | ERA_CLOBM | GTPase Era | Clostridium | <M><F><K><S><G><F><V><T><I><V><G><R><P><N><V><G><K><S><T><L><L><N><A><I><M><K><E><K><L><S><I><V><S><C><R><P><Q><T><T><R><N><N><I><Q><T><I><L><T><E><D><N><Y><Q><L><V><F><V><D><T><P><G><I><H><K><P><K><H><K><L><G><E><Y><M><V><K><S><A><S><D><A><M><K><D><V><D><L><V><L><F><L><I><N><P><D><E><K><P><G><R><G><D><L><F><I><I><E><Q... | An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.<BOP> | B1KZM3 |
Q08465 | YNG1_YEAST | ING1 homolog 1 | Saccharomyces | <M><E><H><L><A><N><E><N><S><D><S><D><I><R><Y><S><F><L><S><T><L><D><H><L><P><C><E><L><I><R><S><L><R><L><M><Q><T><I><D><L><F><K><N><E><E><D><E><P><G><M><E><R><A><C><R><D><L><L><L><V><A><T><Y><I><N><D><L><V><D><D><Q><I><H><F><L><K><Q><H><K><K><E><L><E><I><Q><K><S><V><T><K><N><F><N><S><S><L><E><N><I><K><S><K><L><T><L><E><E... | Histone-binding component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. YNG1 is required for the HAT activity of NuA3 but no... | Q08465 |
C0R2E2 | PURA_BRAHW | IMP--aspartate ligase | Brachyspira | <M><A><S><V><I><I><V><G><T><Q><W><G><D><E><G><K><G><K><I><V><D><Y><L><A><E><N><C><E><Y><V><V><R><S><Q><G><G><S><N><A><G><H><T><V><V><V><D><N><I><K><Y><K><L><R><L><L><P><S><G><I><L><H><K><D><K><V><C><V><I><G><N><G><V><V><I><E><P><K><V><F><L><S><E><I><D><S><L><I><E><K><K><V><N><I><S><N><L><K><I><S><D><R><A><H><V><L><M><P... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | C0R2E2 |
P54997 | DSZB_RHOSG | Dibenzothiophene desulfurization enzyme B | Rhodococcus | <M><T><S><R><V><D><P><A><N><P><G><S><E><L><D><S><A><I><R><D><T><L><T><Y><S><N><C><P><V><P><N><A><L><L><T><A><S><E><S><G><F><L><D><A><A><G><I><E><L><D><V><L><S><G><Q><Q><G><T><V><H><F><T><Y><D><Q><P><A><Y><T><R><F><G><G><E><I><P><P><L><L><S><E><G><L><R><A><P><G><R><T><R><L><L><G><I><T><P><L><L><G><R><Q><G><F><F><V><R><D... | Catalyzes the third and final step of the '4S' desulfurization pathway that removes covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Oxidizes 2-(2'-hydroxyphenyl)benzene sulphinate (HBPS) to 2-hydroxybiphenyl (HBP) plus sulfite . The rate-limiting step of the '4S' desulfurizatio... | P54997 |
Q39255 | SKP1A_ARATH | UFO-binding protein 1 | Arabidopsis | <M><S><A><K><K><I><V><L><K><S><S><D><G><E><S><F><E><V><E><E><A><V><A><L><E><S><Q><T><I><A><H><M><V><E><D><D><C><V><D><N><G><V><P><L><P><N><V><T><S><K><I><L><A><K><V><I><E><Y><C><K><R><H><V><E><A><A><A><S><K><A><E><A><V><E><G><A><A><T><S><D><D><D><L><K><A><W><D><A><D><F><M><K><I><D><Q><A><T><L><F><E><L><I><L><A><A><N><Y... | Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends on the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-bo... | Q39255 |
Q10198 | NDC80_SCHPO | NMS complex subunit ndc80 | Schizosaccharomyces | <M><Q><D><S><S><S><Y><A><R><R><Y><S><Q><A><P><S><S><S><N><L><R><T><T><T><F><G><F><N><G><L><G><T><S><R><T><S><L><A><P><Q><R><T><L><V><N><A><R><Q><S><I><D><P><D><G><L><S><S><R><V><L><T><P><T><M><R><P><S><L><A><P><N><T><R><R><S><S><V><R><V><S><N><A><S><F><I><S><Q><T><P><N><I><T><S><I><K><D><P><R><P><L><S><D><R><R><Y><Q><Q... | Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activ... | Q10198 |
A0T0H9 | RK4_PHATC | 50S ribosomal protein L4, chloroplastic | Phaeodactylum | <M><T><I><Q><K><F><I><T><Y><T><P><L><D><L><N><G><K><Q><L><N><F><N><H><E><L><K><L><N><I><L><E><T><S><G><N><Y><L><V><H><K><D><L><I><R><H><F><G><S><Q><R><Q><A><T><S><S><S><K><T><R><S><E><V><R><G><G><G><R><K><P><W><R><Q><K><G><T><G><K><A><R><A><G><S><N><R><S><P><L><W><K><G><G><G><V><I><F><G><P><K><P><K><K><I><S><L><K><L><N... | Probably binds the 23S rRNA.<BOP> | A0T0H9 |
A5CX29 | RNH_VESOH | Ribonuclease H | Candidatus Vesicomyosocius | <M><M><N><R><I><V><I><Y><T><D><G><G><C><R><C><N><T><G><I><G><G><W><G><V><W><L><K><Y><G><D><Y><D><K><K><L><K><G><N><E><K><K><T><T><N><N><R><M><E><L><T><A><T><I><K><A><L><E><E><I><K><S><N><Q><I><G><I><D><L><F><T><D><S><K><Y><V><I><T><G><I><N><E><W><M><K><N><W><K><V><K><N><W><E><T><S><K><K><R><P><V><K><N><V><D><L><W><Q><R... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | A5CX29 |
P65861 | CRTB_MYCBO | Phytoene synthase | Mycobacterium tuberculosis complex | <M><T><E><I><E><Q><A><Y><R><I><T><E><S><I><T><R><T><A><A><R><N><F><Y><Y><G><I><R><L><L><P><R><E><K><R><A><A><L><S><A><V><Y><A><L><G><R><R><I><D><D><V><A><D><G><E><L><A><P><E><T><K><I><T><E><L><D><A><I><R><K><S><L><D><N><I><D><D><S><S><D><P><V><L><V><A><L><A><D><A><A><R><R><F><P><V><P><I><A><M><F><A><E><L><I><D><G><A><R... | Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable).<BOP> | P65861 |
A1S1K8 | AROE_SHEAM | Shikimate dehydrogenase (NADP(+)) | Shewanella | <M><T><D><R><F><A><V><F><G><N><P><I><S><H><S><K><S><P><Q><I><H><A><M><F><A><K><E><T><G><Q><T><L><T><Y><E><A><I><L><A><P><L><D><G><F><A><E><A><V><T><A><F><M><A><A><G><G><C><G><A><N><V><T><V><P><F><K><E><Q><A><F><T><L><C><D><E><L><S><D><D><A><R><I><A><G><A><V><N><T><L><I><K><L><P><D><G><R><L><R><G><D><N><T><D><G><M><G><L... | Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP> | A1S1K8 |
Q31AD1 | TRHO_PROM9 | tRNA hydroxylation protein O | Prochlorococcus | <M><K><G><K><N><Y><K><I><V><S><L><Y><S><F><F><P><F><Q><E><N><L><I><I><D><L><K><S><K><L><L><E><I><G><Y><E><N><D><L><S><G><L><L><I><F><A><S><E><G><I><N><G><T><I><C><A><E><K><N><V><I><D><I><V><I><N><L><L><N><K><Y><A><D><N><R><N><L><N><I><K><V><N><F><S><K><K><K><V><F><K><K><L><K><I><K><I><K><K><E><I><V><T><M><G><V><P><E><I... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | Q31AD1 |
P04816 | LIVK_ECOLI | Leucine-specific-binding protein | Escherichia | <M><K><R><N><A><K><T><I><I><A><G><M><I><A><L><A><I><S><H><T><A><M><A><D><D><I><K><V><A><V><V><G><A><M><S><G><P><I><A><Q><W><G><D><M><E><F><N><G><A><R><Q><A><I><K><D><I><N><A><K><G><G><I><K><G><D><K><L><V><G><V><E><Y><D><D><A><C><D><P><K><Q><A><V><A><V><A><N><K><I><V><N><D><G><I><K><Y><V><I><G><H><L><C><S><S><S><T><Q><P... | This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids in E.coli.<BOP> | P04816 |
A9IW04 | RS5_BART1 | 30S ribosomal protein S5 | Bartonella | <M><A><Q><K><E><R><G><E><R><E><E><R><D><N><E><F><V><D><R><L><V><H><I><N><R><V><A><K><V><V><K><G><G><R><R><F><G><F><A><A><L><V><V><V><G><D><Q><K><G><R><V><G><F><G><H><G><K><A><R><E><V><P><E><A><V><R><K><A><T><E><S><A><K><R><G><M><I><Y><V><P><L><R><S><G><R><T><L><H><H><D><L><E><G><R><H><G><A><G><R><V><L><L><R><S><A><S><A... | Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP> | A9IW04 |
Q5YTM8 | RPOZ_NOCFA | Transcriptase subunit omega | Nocardia | <M><S><D><T><K><T><A><P><A><Y><D><T><P><I><G><L><T><N><P><P><I><D><E><L><L><E><R><T><S><S><K><Y><A><L><V><I><Y><A><A><K><R><A><R><Q><I><N><D><Y><Y><N><Q><L><G><D><G><I><L><E><Y><V><G><P><L><V><E><P><G><L><Q><E><K><P><L><S><V><A><L><R><E><I><H><A><D><L><L><E><H><S><E><G><E> | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP> | Q5YTM8 |
Q52873 | TRA5_RHIME | Transposase for insertion sequence element ISRM5 | Sinorhizobium | <M><T><K><T><E><G><K><T><A><S><A><A><V><K><D><I><L><L><S><N><P><D><G><L><R><E><V><I><R><T><V><M><Q><E><V><L><E><A><E><M><D><E><A><L><G><A><A><K><G><E><R><T><P><E><R><L><G><Y><R><S><G><H><Y><G><R><T><L><I><T><R><V><G><K><L><E><L><R><V><P><Q><D><R><S><G><H><F><S><T><E><L><F><E><R><Y><Q><R><S><E><R><A><L><V><A><T><L><A><E... | Required for the transposition of the insertion element.<BOP> | Q52873 |
Q0AXL3 | DEF_SYNWW | Polypeptide deformylase | Syntrophomonas | <M><S><V><Y><Q><V><I><T><V><P><N><D><I><L><R><G><K><A><L><P><V><K><E><I><N><A><G><V><L><R><V><L><D><N><M><R><D><T><M><Y><A><A><D><G><V><G><L><A><A><P><Q><I><G><I><P><K><R><M><I><V><V><D><I><G><E><N><L><L><E><L><I><N><P><E><I><L><K><Q><E><G><N><Q><L><G><S><E><G><C><L><S><V><P><G><I><V><G><R><V><N><R><A><K><K><V><L><V><K... | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.<BOP> | Q0AXL3 |
Q6TH22 | DDI2_DANRE | Protein DDI1 homolog 2 | Danio | <M><L><L><T><V><F><C><A><P><R><D><R><S><E><T><T><F><A><L><D><V><S><P><E><L><E><L><R><D><F><L><A><L><C><E><L><E><S><G><I><P><A><G><E><I><Q><I><I><Y><A><E><Q><P><L><Q><D><P><T><R><A><L><G><N><Y><G><L><K><D><G><D><V><L><V><L><R><Q><A><E><R><L><R><A><P><P><Q><P><T><V><P><G><L><P><R><I><D><F><S><S><I><A><V><P><G><T><S><S><G... | Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1. Seems to act as a pr... | Q6TH22 |
P00553 | KKA4_NIACI | Neomycin-kanamycin phosphotransferase type IV | Niallia | <M><N><E><S><T><R><N><W><P><E><E><L><L><E><L><L><G><Q><T><E><L><T><V><N><K><I><G><Y><S><G><D><H><V><Y><H><V><K><E><Y><R><G><T><P><A><F><L><K><I><A><P><S><V><W><W><R><T><L><R><P><E><I><E><A><L><A><W><L><D><G><K><L><P><V><P><K><I><L><Y><T><A><E><H><G><G><M><D><Y><L><L><M><E><A><L><G><G><K><D><G><S><H><E><T><I><Q><A><K><R... | Resistance to butirosin and structurally-related aminoglycosides, including kanamycin and amikacin.<BOP> | P00553 |
A6LJ74 | RPOZ_THEM4 | Transcriptase subunit omega | Thermosipho | <M><N><P><V><I><N><Y><D><E><L><L><K><K><I><P><Y><K><F><A><I><P><I><A><V><A><K><R><A><E><N><L><K><E><F><A><H><S><Y><V><E><T><W><D><N><N><Y><V><S><I><A><L><K><E><L><S><E><G><Y><I><R><I><K><N><E><E><I><L><K><V><L><I><P><N><V><K> | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP> | A6LJ74 |
Q0TBG2 | LIGB_ECOL5 | Polydeoxyribonucleotide synthase [NAD(+)] B | Escherichia | <M><K><V><W><M><A><I><L><I><S><I><L><C><W><Q><S><S><A><W><A><V><C><P><A><W><S><P><A><R><A><Q><E><E><I><S><R><L><Q><Q><Q><I><K><Q><W><D><D><D><Y><W><K><E><G><E><S><E><I><E><D><G><V><Y><D><Q><L><S><A><R><L><T><Q><W><Q><R><C><F><G><N><E><P><R><D><A><M><M><P><P><L><A><G><T><V><M><H><P><V><A><H><T><G><V><R><K><L><A><D><K><N... | Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.<BOP> | Q0TBG2 |
Q4JBK2 | COBS_SULAC | Cobalamin-5'-phosphate synthase | Sulfolobus | <M><G><R><I><L><K><A><I><L><G><Q><L><S><F><F><T><I><I><P><S><P><S><A><S><L><E><E><I><A><E><F><S><F><I><S><P><L><M><V><G><I><I><T><G><I><I><D><W><F><V><V><L><L><G><I><R><L><I><G><S><L><G><A><L><L><L><I><P><T><V><E><I><I><R><G><F><H><H><L><D><G><L><L><D><M><G><D><A><L><M><V><G><K><E><R><R><P><Q><V><L><H><D><L><Q><T><G><S... | Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.<BOP> | Q4JBK2 |
Q5FLV7 | IXTPA_LACAC | Nucleoside-triphosphate pyrophosphatase | Lactobacillus | <M><S><Q><K><I><L><F><A><T><G><N><K><G><K><A><R><E><L><K><E><A><F><K><T><A><G><V><D><V><E><I><I><T><N><S><D><L><D><N><P><P><H><P><I><E><S><G><R><T><F><E><A><N><A><K><I><K><A><H><E><L><A><D><Y><S><K><L><P><T><I><A><D><D><S><G><L><M><V><D><A><L><N><G><E><P><G><V><R><S><A><R><Y><A><G><E><A><H><N><D><A><K><N><N><A><K><L><L... | Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical p... | Q5FLV7 |
C0HK90 | CPFB3_XENBO | Caerulein precursor fragment B3 | Xenopus | <G><L><G><S><L><L><G><S><L><F><K><F><I><P><K><L><L><P><S><I><Q><Q> | Has antibacterial and antifungal activity.<BOP> | C0HK90 |
Q589B1 | PSBK_SILLA | Photosystem II reaction center protein K | Silene sect. Melandrium | <M><L><N><I><F><S><L><I><G><L><N><S><A><L><Y><S><S><S><C><F><F><A><K><L><P><E><A><Y><A><F><L><S><P><I><V><D><F><M><P><V><I><P><L><L><F><F><L><L><A><F><V><W><Q><A><A><V><S><F><R> | One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a... | Q589B1 |
Q8Z171 | ULAB_SALTI | Ascorbate-specific phosphotransferase enzyme IIB component | Salmonella | <M><T><V><R><I><L><A><V><C><G><N><G><Q><G><S><S><M><I><M><K><M><K><V><D><Q><F><L><T><Q><S><N><I><D><H><T><V><N><S><C><A><V><G><E><Y><K><S><E><L><S><G><A><D><I><I><I><A><S><T><H><I><A><G><E><I><T><V><T><G><N><K><Y><V><V><G><V><R><N><M><L><S><P><A><D><F><G><P><K><L><L><E><V><I><K><A><H><F><P><Q><D><V><K> | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | Q8Z171 |
Q8VP65 | AROA_PHODP | 5-enolpyruvylshikimate-3-phosphate synthase | Photobacterium | <M><E><S><L><T><L><Q><P><I><N><L><I><N><G><E><V><N><L><P><G><S><K><S><V><S><N><R><A><L><L><L><A><A><L><A><Q><G><T><T><R><L><T><N><L><L><D><S><D><D><I><R><H><M><L><N><A><L><Q><Q><L><G><V><Q><Y><Q><L><S><A><D><K><T><E><C><T><V><E><G><L><G><Q><P><F><S><V><K><D><F><T><C><L><Y><L><G><N><A><G><T><A><M><R><P><L><A><A><A><L><C... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP> | Q8VP65 |
P31440 | ADEQ_ECOLI | Adenine permease AdeQ | Escherichia | <M><N><N><D><N><T><D><Y><V><S><N><E><S><G><T><L><S><R><L><F><K><L><P><Q><H><G><T><T><V><R><T><E><L><I><A><G><M><T><T><F><L><T><M><V><Y><I><V><F><V><N><P><Q><I><L><G><A><A><Q><M><D><P><K><V><V><F><V><T><T><C><L><I><A><G><I><G><S><I><A><M><G><I><F><A><N><L><P><V><A><L><A><P><A><M><G><L><N><A><F><F><A><F><V><V><V><G><A><M... | High-affinity transporter for adenine.<BOP> | P31440 |
Q1I7T2 | GLO2_PSEE4 | Glyoxalase II | Pseudomonas | <M><I><Q><I><D><A><L><P><A><F><S><D><N><Y><I><W><L><L><Q><D><T><A><N><R><R><C><A><V><V><D><P><G><D><D><A><P><V><L><A><W><L><G><K><H><P><G><W><V><L><E><A><I><L><V><T><H><H><H><H><D><H><V><G><G><V><E><A><L><K><H><A><T><G><A><Q><V><F><G><P><A><N><E><R><I><P><A><R><D><I><A><L><E><D><G><A><Q><V><H><V><L><G><L><A><F><D><V><L... | Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.<BOP> | Q1I7T2 |
Q5FFA3 | PTH_EHRRG | Peptidyl-tRNA hydrolase | Ehrlichia | <M><L><H><L><L><V><G><L><G><N><P><G><K><E><Y><E><L><T><R><H><N><V><G><F><M><I><I><D><A><I><M><H><H><F><L><F><P><D><F><K><K><K><H><N><A><L><I><S><S><G><S><I><Q><S><Y><K><V><I><L><A><K><P><Y><T><F><M><N><N><S><G><A><P><I><S><S><I><V><K><L><Y><K><I><P><L><D><N><I><I><V><F><H><D><E><T><D><I><D><F><C><T><I><R><I><K><K><G><G... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | Q5FFA3 |
Q9R061 | NUBP2_MOUSE | Nucleotide-binding protein 2 | Mus | <M><E><A><A><A><G><E><R><A><E><P><G><N><L><A><G><V><R><H><I><I><L><V><L><S><G><K><G><G><V><G><K><S><T><I><S><T><E><L><A><L><A><L><R><H><Q><G><K><K><V><G><I><L><D><V><D><L><C><G><P><S><I><P><H><M><L><R><A><Q><G><K><A><V><H><Q><C><D><N><G><W><V><P><V><F><V><D><Q><E><Q><S><I><S><L><M><S><V><G><F><L><L><E><N><P><D><E><A><V... | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium... | Q9R061 |
B1KP09 | MOAC_SHEWM | Molybdenum cofactor biosynthesis protein C | Shewanella | <M><S><N><E><F><T><H><I><N><A><D><G><N><A><H><M><V><D><V><T><E><K><A><V><T><E><R><E><A><R><A><E><A><F><I><E><M><A><P><A><T><L><E><M><I><M><S><G><S><H><H><K><G><D><V><F><A><T><A><R><I><A><G><I><Q><A><A><K><K><T><S><D><L><I><P><L><C><H><P><L><M><L><T><K><V><E><V><E><L><E><A><Q><P><E><H><S><R><V><R><I><T><S><L><C><K><L><S... | Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).<BOP> | B1KP09 |
B1LMN0 | HEM6_ECOSM | Oxygen-dependent coproporphyrinogen-III oxidase | Escherichia | <M><K><P><D><A><H><Q><V><K><Q><F><L><L><N><L><Q><D><T><I><C><Q><Q><L><S><A><V><D><G><A><E><F><V><E><D><S><W><L><R><E><A><G><G><G><G><R><S><R><V><L><R><N><G><G><V><F><E><Q><A><G><V><N><F><S><H><V><H><G><E><V><M><P><A><S><A><T><A><H><R><P><E><L><A><G><R><S><F><E><A><M><G><V><S><L><V><V><H><P><H><N><P><Y><V><P><T><S><H><A... | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP> | B1LMN0 |
Q9CQ56 | USE1_MOUSE | USE1-like protein | Mus | <M><A><Q><A><E><G><A><Y><H><R><P><L><A><T><S><R><L><E><L><N><L><V><R><L><L><C><R><C><E><S><M><A><A><E><K><R><E><P><D><E><W><R><L><E><K><Y><V><G><A><L><E><D><M><L><Q><A><L><K><V><Q><A><S><K><P><A><S><E><V><I><S><E><Y><S><R><K><V><D><F><L><K><G><M><L><Q><A><E><K><L><T><S><S><S><E><K><A><L><A><N><Q><F><L><A><P><G><R><V><P... | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.<BOP> | Q9CQ56 |
B8H6U2 | HIS6_PSECP | ImGP synthase subunit HisF | Pseudarthrobacter | <M><A><V><A><V><R><V><I><P><C><L><D><V><D><A><G><R><V><V><K><G><V><N><F><E><G><L><R><D><A><G><D><P><V><E><L><A><H><R><Y><D><N><A><G><A><D><E><L><T><F><L><D><V><T><A><S><S><G><N><R><E><T><T><F><D><V><V><R><R><T><A><E><E><V><F><I><P><L><C><V><G><G><G><V><R><G><V><A><E><V><D><K><L><L><R><F><G><A><D><K><A><A><I><N><T><A><A... | IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP> | B8H6U2 |
P21916 | NEU2_STRCA | MSEL-neurophysin | Struthio | <A><L><A><D><A><A><L><R><Q><C><M><P><C><G><P><G><D><R><G><N><C><F><G><P><S><I><C><C><G><A><E><L><G><C><Y><V><G><T><A><E><T><L><R><C><A><E><E><N><Y><L><P><S><P><C><R><A><G><G><Q><P><C><G><A><G><G><R><C><A><A><P><G><I><C><C><S><D><E><T><C><S><L><E><P><A><C><L><E><E><A><G><E><R><G><G><E><P><A><Q><K><N><L><T><G><L><D><A><S... | Neurophysin 2 specifically binds vasopressin.<BOP> | P21916 |
Q6ZN68 | D19P2_HUMAN | Protein dpy-19 homolog 2-like 2 | Homo | <M><A><D><S><R><R><V><I><I><A><S><W><Y><R><T><F><M><G><I><V><N><L><F><G><L><E><T><K><T><C><W><N><V><T><R><I><E><P><L><N><E><V><Q><S><C><E><G><L><R><D><P><A><C><F><Y><V><G><V><I><F><I><L><N><G><L><M><M><G><L><F><F><I><Y><G><T><Y><L><S><G><T><E><L><G><G><L><I><T><V><L><C><F><F><F><N><H><G><E><A><T><C><V><M><W><T><P><P><L... | Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.<BOP> | Q6ZN68 |
P02707 | LECH_CHICK | Hepatic lectin | Gallus | <M><D><E><E><R><L><S><D><N><V><R><L><Y><K><G><G><S><I><R><Q><G><L><R><S><F><A><A><V><Y><V><L><L><A><L><S><F><L><L><L><T><L><L><S><S><V><S><L><A><R><I><A><A><L><S><S><K><L><S><T><L><Q><S><E><P><K><H><N><F><S><S><R><D><S><L><L><F><P><C><G><A><Q><S><R><Q><W><E><Y><F><E><G><R><C><Y><Y><F><S><L><S><R><M><S><W><H><K><A><K><A... | Hepatic lectin is a membrane receptor protein that recognizes and binds exposed N-acetylglucosamine moieties of plasma glycoproteins, thus mediating their clearance (from the circulation) and endocytosis.<BOP> | P02707 |
B2U9Q0 | ACCA_RALPJ | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Ralstonia | <M><K><T><T><F><L><E><F><E><Q><P><I><A><E><L><E><A><K><I><E><E><L><R><F><V><Q><D><D><S><A><V><D><I><S><E><E><I><S><R><L><A><S><K><S><Q><Q><L><T><K><D><L><Y><A><N><L><T><P><W><Q><V><A><Q><I><A><R><H><P><Q><R><P><Y><T><L><D><Y><V><R><E><I><F><T><D><F><H><E><L><H><G><D><R><T><F><A><D><D><L><S><I><V><G><G><L><A><R><F><N><G... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP> | B2U9Q0 |
P37451 | PDUF_SALTY | Propanediol uptake facilitator PduF | Salmonella | <M><N><D><S><L><K><A><Q><C><G><A><E><F><L><G><T><G><L><F><L><F><F><G><I><G><C><L><S><A><L><K><V><A><G><A><S><L><G><L><W><E><I><C><I><I><W><G><L><G><I><S><L><A><V><Y><L><T><A><G><I><S><G><G><H><L><N><P><A><V><T><I><A><L><W><L><F><A><C><F><P><K><Q><K><V><L><P><Y><I><I><A><Q><F><A><G><A><F><G><G><A><L><L><A><Y><V><L><Y><S... | The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.<BOP> | P37451 |
Q5HUF2 | TGT_CAMJR | tRNA-guanine transglycosylase | Campylobacter | <M><E><F><K><L><K><H><K><D><G><M><A><R><V><C><E><I><T><T><A><H><S><T><F><L><T><P><V><F><M><P><V><G><T><V><G><A><V><K><S><L><D><A><N><D><M><K><N><E><L><D><A><K><I><I><L><A><N><T><Y><H><M><Y><L><R><P><T><S><K><V><V><K><D><F><G><G><L><H><G><F><T><K><F><D><R><S><F><L><T><D><S><G><G><F><Q><A><F><S><L><S><K><N><S><K><H><F><N... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q5HUF2 |
Q5LC42 | PYRG_BACFN | UTP--ammonia ligase | Bacteroides | <M><G><E><T><K><Y><I><F><V><T><G><G><V><A><S><S><L><G><K><G><I><I><S><S><S><I><G><K><L><L><Q><A><R><G><Y><K><V><T><I><Q><K><F><D><P><Y><I><N><I><D><P><G><T><L><N><P><Y><E><H><G><E><C><Y><V><T><V><D><G><H><E><A><D><L><D><L><G><H><Y><E><R><F><L><G><I><Q><T><T><K><A><N><N><I><T><T><G><R><I><Y><K><S><V><I><D><K><E><R><R><G... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP> | Q5LC42 |
Q75D30 | ERI1_ASHGO | Endoplasmic reticulum-associated Ras inhibitor protein 1 | Eremothecium | <M><N><D><K><V><A><A><T><L><V><L><V><V><T><Y><S><I><V><G><A><S><L><W><C><L><T><Y><A><W><H><D><E><T><K><L><Y><Y><W><C><I><V><Q><L><L><P><V><M><L><W><V><W><C><V><I><S><W><C><G><A><Q><L><F><G><Y><A><K><R><G><K><A><D> | Probable component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI-anchors for cell surface proteins.<BOP> | Q75D30 |
B5XWP0 | SYY_KLEP3 | Tyrosyl-tRNA synthetase | Klebsiella | <M><A><S><S><N><L><I><K><Q><L><Q><E><R><G><L><V><A><Q><V><T><D><E><E><A><L><A><E><R><L><A><Q><G><P><I><A><L><Y><C><G><F><D><P><T><A><D><S><L><H><L><G><H><L><V><P><L><L><C><L><K><R><F><Q><Q><A><G><H><K><P><V><A><L><V><G><G><A><T><G><L><I><G><D><P><S><F><K><A><A><E><R><K><L><N><T><E><D><T><V><Q><E><W><V><D><K><I><R><K><Q... | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<BOP> | B5XWP0 |
A1USB4 | GATB_BARBK | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Bartonella | <M><Q><M><I><D><I><R><P><P><D><P><R><H><F><I><S><G><S><T><G><D><W><E><V><V><I><G><M><E><V><H><A><Q><I><V><S><D><S><K><L><F><S><G><A><S><T><K><F><G><A><E><P><N><N><H><V><S><L><I><D><A><A><M><P><G><M><L><P><V><V><N><Q><E><C><I><R><Q><A><I><R><T><G><L><G><L><K><A><Q><I><N><L><K><S><V><F><D><R><K><N><Y><F><Y><P><D><L><P><Q... | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | A1USB4 |
A6SZM5 | GUAA_JANMA | Glutamine amidotransferase | Janthinobacterium | <M><H><S><K><I><L><I><L><D><F><G><S><Q><V><T><Q><L><I><A><R><R><V><R><D><S><G><V><F><S><E><V><F><P><Y><D><V><S><D><E><F><V><R><N><Y><G><A><A><G><V><I><L><S><G><G><P><N><S><V><I><E><G><D><E><S><P><R><V><P><Q><A><V><F><E><L><G><V><P><V><M><G><I><C><Y><G><M><Q><A><M><A><E><Q><L><G><G><K><V><E><N><G><K><V><R><E><F><G><Y><A... | Catalyzes the synthesis of GMP from XMP.<BOP> | A6SZM5 |
Q1G9R3 | DNAJ_LACDA | Chaperone protein DnaJ | Lactobacillus | <M><A><A><N><R><D><Y><Y><D><V><L><G><V><S><R><D><A><S><D><A><E><I><S><K><A><Y><R><K><L><A><K><K><Y><H><P><D><L><N><H><E><A><G><A><E><E><K><Y><K><E><V><N><E><A><Y><E><V><L><H><D><P><Q><K><R><Q><Q><Y><D><Q><F><G><Q><A><G><M><N><G><Q><G><G><F><G><G><Q><Y><G><G><Q><G><F><G><G><A><D><F><G><D><F><G><D><I><F><S><S><F><F><G><G... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | Q1G9R3 |
B1Z181 | SELD_BURA4 | Selenophosphate synthase | Burkholderia cepacia complex | <M><T><E><A><T><L><T><P><P><A><V><P><R><L><T><S><L><S><H><G><G><G><C><G><C><K><I><A><P><G><V><L><S><E><L><L><K><R><A><T><P><P><A><L><F><P><D><L><L><V><G><T><E><T><S><D><D><A><A><V><Y><R><L><N><D><E><Q><A><I><V><A><T><T><D><F><F><M><P><I><V><D><D><P><F><D><F><G><R><I><A><A><T><N><A><L><S><D><V><Y><A><M><G><G><K><P><I><L... | Synthesizes selenophosphate from selenide and ATP.<BOP> | B1Z181 |
P66878 | COBIJ_MYCBO | S-adenosyl-L-methionine--precorrin-3B methyltransferase | Mycobacterium tuberculosis complex | <M><S><A><R><G><T><L><W><G><V><G><L><G><P><G><D><P><E><L><V><T><V><K><A><A><R><V><I><G><E><A><D><V><V><A><Y><H><S><A><P><H><G><H><S><I><A><R><G><I><A><E><P><Y><L><R><P><G><Q><L><E><E><H><L><V><Y><P><V><T><T><E><A><T><N><H><P><G><G><Y><A><G><A><L><E><D><F><Y><A><D><A><T><E><R><I><A><T><H><L><D><A><G><R><N><V><A><L><L><A... | Methylates precorrin-2 at the C-20 position to produce precorrin-3A.<BOP> | P66878 |
B7JYV9 | RF3_RIPO1 | Peptide chain release factor 3 | Rippkaea orientalis | <M><S><S><E><L><Q><T><E><I><Q><E><A><V><E><K><R><R><N><F><A><I><I><S><H><P><D><A><G><K><T><T><L><T><E><K><L><L><L><Y><G><G><A><I><H><Q><A><G><A><V><K><A><R><R><D><Q><R><K><A><T><S><D><W><M><E><M><E><K><Q><R><G><I><S><I><T><S><T><V><L><Q><F><E><Y><R><N><F><Q><I><N><L><L><D><T><P><G><H><Q><D><F><S><E><D><T><Y><R><T><L><A... | Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP> | B7JYV9 |
Q08A71 | ANM6_ARATH | Probable protein arginine N-methyltransferase 6 | Arabidopsis | <M><Q><S><G><G><D><F><S><N><G><F><H><G><D><H><H><R><E><L><E><L><E><D><K><Q><G><P><S><L><S><S><F><G><R><A><K><K><R><S><H><A><G><A><R><D><P><R><G><G><L><A><N><V><L><R><V><S><D><Q><L><G><E><H><K><S><L><E><T><S><E><S><S><P><P><P><C><T><D><F><D><V><A><Y><F><H><S><Y><A><H><V><G><I><H><E><E><M><I><K><D><R><A><R><T><E><T><Y><R... | Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).<BOP> | Q08A71 |
A1KVS7 | MTGA_NEIMF | Peptidoglycan glycosyltransferase MtgA | Neisseria | <M><F><R><I><V><K><W><L><I><A><L><P><V><G><I><F><I><F><F><N><A><Y><V><Y><G><N><I><I><T><Y><R><A><V><A><P><H><R><T><A><F><M><S><M><R><M><K><Q><F><E><Q><E><G><R><D><V><A><L><D><Y><R><W><V><P><Y><N><R><I><S><V><N><L><K><K><A><L><I><A><S><E><D><A><H><F><A><G><H><G><G><F><D><W><G><G><I><Q><N><A><I><R><R><N><R><N><S><G><K><V... | Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.<BOP> | A1KVS7 |
Q8DPQ5 | PYRC_STRR6 | Dihydroorotase | Streptococcus | <M><L><L><I><K><N><G><R><V><M><D><P><K><S><G><L><D><Q><V><C><D><V><L><V><Q><D><G><K><I><I><K><I><A><P><E><I><T><E><E><G><A><E><T><I><D><A><T><G><H><V><V><A><P><G><L><V><D><I><H><V><H><F><R><E><P><G><Q><T><H><K><E><D><I><H><T><G><A><L><A><A><A><A><G><G><F><T><T><V><V><M><M><A><N><T><S><P><T><I><S><D><V><E><T><L><Q><A><V... | Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.<BOP> | Q8DPQ5 |
P13582 | EAST_DROME | Serine protease easter | Sophophora | <M><L><K><P><S><I><I><C><L><F><L><G><I><L><A><K><S><S><A><G><Q><F><Y><F><P><N><E><A><A><Q><V><P><N><Y><G><R><C><I><T><P><N><R><E><R><A><L><C><I><H><L><E><D><C><K><Y><L><Y><G><L><L><T><T><T><P><L><R><D><T><D><R><L><Y><L><S><R><S><Q><C><G><Y><T><N><G><K><V><L><I><C><C><P><D><R><Y><R><E><S><S><S><E><T><T><P><P><P><K><P><N... | Component of the extracellular signaling pathway that establishes the dorsal-ventral pathway of the embryo . Three proteases; ndl, gd and snk process easter to create active easter . Active easter defines cell identities along the dorsal-ventral continuum by activating the spz ligand for the Tl receptor in the ventral ... | P13582 |
Q8NQV2 | DDL_CORGL | D-alanylalanine synthetase | Corynebacterium | <M><S><N><S><N><S><G><K><V><R><V><A><V><V><Y><G><G><R><S><S><E><H><S><V><S><C><V><S><A><G><A><I><M><A><H><L><D><P><E><K><Y><D><V><I><P><V><G><I><T><V><D><G><A><W><V><V><G><E><T><D><P><Q><K><L><T><L><I><D><R><T><M><P><E><V><E><H><H><E><E><V><R><P><S><L><D><P><A><H><R><G><E><F><H><F><S><D><G><S><L><Y><A><T><A><D><V><I><F... | Cell wall formation.<BOP> | Q8NQV2 |
Q8VTT5 | HYDA_RALPI | D-hydantoinase | Ralstonia | <M><D><I><I><I><K><N><G><T><I><V><T><A><D><G><I><S><R><A><D><L><G><I><K><D><G><K><I><T><Q><I><G><G><A><L><G><P><A><E><R><T><I><D><A><A><G><R><Y><V><F><P><G><G><I><D><V><H><T><H><V><E><T><V><S><F><N><T><Q><S><A><D><T><F><A><T><A><T><V><A><A><A><C><G><G><T><T><T><I><V><D><F><C><Q><Q><D><R><G><H><S><L><A><E><A><V><A><K><W... | Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives.<BOP> | Q8VTT5 |
D5FM34 | NAS35_HAECO | Procollagen C-proteinase | Haemonchus | <M><S><L><L><R><S><A><S><L><L><L><V><V><V><T><A><A><L><P><P><C><T><L><G><Y><S><L><H><D><G><S><R><L><D><D><V><I><A><E><F><T><A><E><R><R><P><R><R><L><A><T><P><A><Q><R><R><L><M><G><L><T><E><E><Q><H><K><T><V><Q><F><Y><L><D><K><L><R><E><L><G><N><R><R><H><P><E><S><Y><N><K><D><S><P><K><N><E><A><Y><K><W><R><K><Q><M><R><D><D><L... | Metalloprotease which cleaves the carboxyl terminus of procollagens to mature collagens. Probably involved in cuticular collagen maturation.<BOP> | D5FM34 |
Q6C093 | UBC2_YARLI | Ubiquitin-protein ligase UBC2 | Yarrowia | <M><S><T><T><A><R><R><R><L><M><R><D><F><K><R><M><Q><Q><D><P><P><Q><G><V><S><A><S><P><V><A><D><N><V><L><T><W><N><A><V><I><I><G><P><A><E><T><P><F><E><D><G><T><F><R><M><V><L><Q><F><D><E><Q><Y><P><N><K><P><P><A><V><K><F><V><S><Q><M><F><H><P><N><V><Y><S><S><G><E><L><C><L><D><I><L><Q><N><R><W><S><P><T><Y><D><V><A><A><I><L><T... | Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also i... | Q6C093 |
Q51463 | FLIF_PSEAE | Flagellar M-ring protein | Pseudomonas | <M><A><D><A><L><I><D><S><Q><V><P><A><K><S><G><G><A><G><M><L><K><K><S><F><P><G><L><S><F><L><D><N><L><S><E><M><T><M><L><R><Q><I><G><L><L><V><G><L><A><A><S><V><A><I><G><F><A><V><V><L><W><S><Q><Q><P><D><Y><K><P><L><Y><G><S><L><N><G><V><D><A><N><R><V><V><E><A><L><T><A><A><D><I><P><Y><K><V><E><P><N><S><G><A><L><L><V><K><A><D... | The M ring may be actively involved in energy transduction.<BOP> | Q51463 |
P36053 | ELF1_YEAST | Transcription elongation factor 1 | Saccharomyces | <M><G><K><R><K><K><S><T><R><K><P><T><K><R><L><V><Q><K><L><D><T><K><F><N><C><L><F><C><N><H><E><K><S><V><S><C><T><L><D><K><K><N><S><I><G><T><L><S><C><K><I><C><G><Q><S><F><Q><T><R><I><N><S><L><S><Q><P><V><D><V><Y><S><D><W><F><D><A><V><E><E><V><N><S><G><R><G><S><D><T><D><D><G><D><E><G><S><D><S><D><Y><E><S><D><S><E><Q><D><A... | Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.<BOP> | P36053 |
P07947 | YES_HUMAN | p61-Yes | Homo | <M><G><C><I><K><S><K><E><N><K><S><P><A><I><K><Y><R><P><E><N><T><P><E><P><V><S><T><S><V><S><H><Y><G><A><E><P><T><T><V><S><P><C><P><S><S><S><A><K><G><T><A><V><N><F><S><S><L><S><M><T><P><F><G><G><S><S><G><V><T><P><F><G><G><A><S><S><S><F><S><V><V><P><S><S><Y><P><A><G><L><T><G><G><V><T><I><F><V><A><L><Y><D><Y><E><A><R><T><T... | Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR leads to recruitment of YES1 to the phosphorylated recep... | P07947 |
Q8DSG3 | SYDND_STRMU | Non-discriminating aspartyl-tRNA synthetase | Streptococcus | <M><K><E><L><F><I><G><N><Y><G><L><E><Q><V><G><Q><K><V><T><A><K><G><W><V><A><N><I><R><N><H><G><K><L><A><F><I><E><L><R><D><R><E><G><L><L><Q><V><F><V><D><S><A><V><A><D><F><D><K><L><H><D><L><H><K><E><S><I><L><A><V><T><G><E><I><V><A><R><D><E><R><F><V><N><P><H><I><K><S><G><Q><V><E><L><R><A><E><T><I><E><I><I><A><S><S><K><L><L... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP> | Q8DSG3 |
Q2GHV0 | ISPF_EHRCR | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Ehrlichia | <M><N><Q><H><P><N><K><P><I><F><K><V><G><I><G><Y><D><V><H><K><F><D><N><T><C><Y><N><D><A><N><T><F><I><T><I><C><G><I><K><I><N><Y><H><K><K><I><I><A><H><S><D><G><D><V><G><L><H><A><L><T><D><A><I><L><G><A><V><G><C><G><S><I><G><Q><H><F><P><N><T><D><N><T><W><K><N><I><K><S><D><Y><F><L><I><E><A><Q><K><K><A><Q><E><K><G><Y><S><I><S... | Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond... | Q2GHV0 |
A1UCA4 | ADD_MYCSK | Adenosine aminohydrolase | unclassified Mycobacterium | <M><T><T><P><L><T><L><E><N><I><S><Q><A><P><K><A><L><L><H><D><H><L><D><G><G><L><R><P><S><T><V><L><E><L><A><G><Q><Y><G><Y><D><D><L><P><A><D><D><V><D><E><L><A><T><F><F><R><T><A><A><H><S><G><S><L><V><R><Y><L><E><P><F><A><H><T><V><G><V><M><Q><T><A><E><A><L><H><R><V><A><F><E><C><V><E><D><L><A><G><D><N><V><V><Y><A><E><V><R><F... | Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.<BOP> | A1UCA4 |
B6YVT5 | RNH2_THEON | Ribonuclease HII | Thermococcus | <M><K><L><A><G><I><D><E><A><G><R><G><P><V><L><G><P><M><V><I><A><A><V><V><V><D><E><G><N><V><P><K><L><E><E><L><G><V><K><D><S><K><K><L><T><P><K><R><R><E><R><L><F><D><E><I><V><Q><L><L><D><D><Y><V><I><L><E><L><W><P><E><E><I><D><S><R><E><G><T><L><N><E><F><E><V><E><N><F><V><K><A><L><N><S><L><K><V><K><P><D><V><V><Y><I><D><A><A... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | B6YVT5 |
Q4L7U0 | LEU1_STAHJ | Alpha-isopropylmalate synthase | Staphylococcus | <M><E><S><H><I><Q><I><F><D><T><T><L><R><D><G><E><Q><T><P><G><V><N><F><S><F><D><E><R><L><K><I><A><K><Q><L><E><T><W><G><V><D><I><L><E><A><G><F><P><A><S><S><A><G><S><F><K><S><V><Q><A><I><S><N><T><L><T><K><T><A><V><C><G><L><A><R><C><K><K><S><D><I><D><A><V><Y><E><A><T><K><D><A><V><K><P><V><I><H><V><F><I><A><T><S><P><I><H><L... | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP> | Q4L7U0 |
Q96EH3 | MASU1_HUMAN | Mitochondrial assembly of ribosomal large subunit protein 1 | Homo | <M><G><P><G><G><R><V><A><R><L><L><A><P><L><M><W><R><R><A><V><S><S><V><A><G><S><A><V><G><A><E><P><G><L><R><L><L><A><V><Q><R><L><P><V><G><A><A><F><C><R><A><C><Q><T><P><N><F><V><R><G><L><H><S><E><P><G><L><E><E><R><A><E><G><T><V><N><E><G><R><P><E><S><D><A><A><D><H><T><G><P><K><F><D><I><D><M><M><V><S><L><L><R><Q><E><N><A><R... | Required for normal mitochondrial ribosome function and mitochondrial translation . May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge... | Q96EH3 |
P0DN22 | ALMA1_DURXX | Symbiodinium-A1 | Symbiodinium | <M><P><L><I><L><G><G><L><A><G><A><A><A><G><Y><G><A><A><A><W><L><E><R><R><K><P><P><P><G><K><D><P><N><I><K><H><A><S><L><G><V><V><R><L><D><W><H><Y><H><P><L><P><G><D><V><G><S><P><D><S><F><E><Y><P><V><Y><Y><R><A><V><P><G><L><T><F><E><I><C><Q><S><G><K><M><S><P><E><I><Q><Q><N><F><K><D><A><I><E><F><L><D><K><E><R><G><V><S><V><I... | Mediates cleavage of dimethylsulfonioproprionate (DMSP) into dimethyl sulfide (DMS) and acrylate. DMS is the principal form by which sulfur is transported from oceans to the atmosphere and is a key component of the ocean sulfur cycle.<BOP> | P0DN22 |
Q63AJ1 | KYNB_BACCZ | N-formylkynurenine formamidase | Bacillus cereus group | <M><K><T><S><E><W><I><D><I><S><Q><P><L><N><N><D><I><A><T><W><P><G><D><T><P><F><S><Y><E><V><S><W><S><K><E><E><S><G><S><V><N><V><G><K><L><T><M><S><I><H><T><G><T><H><I><D><A><P><F><H><F><D><N><E><G><K><K><V><I><D><L><D><V><Q><V><Y><V><G><P><A><R><I><I><D><V><S><N><L><E><S><I><G><K><K><E><L><E><N><F><H><L><E><G><V><E><R><L... | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.<BOP> | Q63AJ1 |
O82139 | CAS1_PANGI | Phytosterol synthase | Panax | <M><W><K><L><K><I><A><E><G><G><N><P><W><L><R><T><L><N><D><H><V><G><R><Q><I><W><E><F><D><P><N><I><G><S><P><E><E><L><A><E><V><E><K><V><R><E><N><F><R><N><H><R><F><E><K><K><H><S><A><D><L><L><M><R><I><Q><F><A><N><E><N><P><G><S><V><V><L><P><Q><V><K><V><N><D><G><E><D><I><S><E><D><K><V><T><V><T><L><K><R><A><M><S><F><Y><S><T><L... | Component of the phytosterols biosynthetic pathways (Probable). Oxidosqualene cyclase converting oxidosqualene to cycloartenol .<BOP> | O82139 |
Q9NYL5 | CP39A_HUMAN | Oxysterol 7-alpha-hydroxylase | Homo | <M><E><L><I><S><P><T><V><I><I><I><L><G><C><L><A><L><F><L><L><L><Q><R><K><N><L><R><R><P><P><C><I><K><G><W><I><P><W><I><G><V><G><F><E><F><G><K><A><P><L><E><F><I><E><K><A><R><I><K><Y><G><P><I><F><T><V><F><A><M><G><N><R><M><T><F><V><T><E><E><E><G><I><N><V><F><L><K><S><K><K><V><D><F><E><L><A><V><Q><N><I><V><Y><R><T><A><S><I... | A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis . Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and r... | Q9NYL5 |
B0BWS2 | DDL_RICRO | D-alanylalanine synthetase | spotted fever group | <M><H><K><Y><Q><T><H><W><V><E><H><S><I><V><K><I><L><S><S><T><G><K><K><H><I><A><L><M><A><G><G><M><S><A><E><R><E><V><S><L><V><S><S><E><G><V><S><K><A><L><I><E><L><G><Y><R><V><T><F><I><D><M><G><A><D><I><A><V><R><L><Q><E><I><K><P><D><I><V><F><N><C><L><H><G><T><Y><G><E><D><G><G><L><P><G><L><L><N><I><M><R><I><P><Y><T><H><S><G... | Cell wall formation.<BOP> | B0BWS2 |
Q0SWX6 | DNAA_CLOPS | Chromosomal replication initiator protein DnaA | Clostridium | <M><D><A><Q><L><N><N><L><W><E><Q><A><L><N><I><I><K><G><E><I><S><E><I><S><F><N><T><W><I><K><S><C><T><P><I><S><I><S><D><N><I><L><K><L><S><V><P><N><E><F><T><K><G><I><L><D><T><R><Y><K><D><L><L><I><Q><A><L><K><I><V><T><S><R><K><F><K><I><E><F><Y><L><E><S><D><L><E><E><E><K><E><N><E><E><K><Q><K><E><E><K><K><D><N><T><N><D><V><D... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | Q0SWX6 |
P29540 | T2EB_XENLA | Transcription initiation factor IIE subunit beta | Xenopus | <M><D><P><A><L><L><R><D><R><E><L><F><K><K><R><A><L><T><T><P><A><V><E><K><R><P><S><A><S><S><E><S><S><K><K><K><R><A><K><L><E><L><S><S><T><S><G><S><K><P><S><S><D><G><S><N><G><S><F><N><L><K><S><L><S><G><S><S><G><Y><K><F><G><V><L><A><K><I><V><N><Y><M><K><T><R><H><Q><R><G><D><T><Y><P><L><T><L><E><E><I><L><D><E><T><Q><H><L><D... | Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.<BOP> | P29540 |
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