accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q161G7 | YBEY_ROSDO | Endoribonuclease YbeY | Roseobacter | <M><D><I><D><I><L><I><E><D><D><R><W><A><A><M><D><L><D><V><L><V><R><D><V><L><R><A><I><S><D><T><L><T><L><D><L><A><A><A><E><V><S><Y><L><A><C><D><D><A><R><I><A><L><L><N><A><D><F><R><E><K><A><T><A><T><N><V><L><S><W><P><A><A><D><L><A><P><V><V><A><G><A><V><P><T><T><P><T><V><D><V><T><G><A><L><T><L><G><D><V><A><I><A><Y><E><T><C... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q161G7 |
Q82VF0 | TGT_NITEU | tRNA-guanine transglycosylase | Nitrosomonas | <M><K><F><Q><L><H><C><R><D><H><E><A><R><R><G><T><L><T><L><A><H><G><T><V><E><T><P><A><F><M><P><V><G><T><Y><G><A><V><K><G><L><S><P><D><E><L><H><T><L><G><A><G><I><I><L><G><N><T><F><H><L><W><L><R><P><G><L><E><V><I><G><A><H><G><G><L><H><R><L><M><N><W><D><G><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><G><A><L><R><K><I><C><E><E... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q82VF0 |
P21797 | TNNC1_BALNU | Troponin C, isoform 1 | Balanus | <S><P><D><G><E><Y><A><E><E><T><G><L><E><K><E><Q><I><V><V><L><R><R><A><F><D><S><F><D><R><D><K><K><G><Y><I><S><P><E><T><V><S><D><I><L><R><M><M><G><I><K><V><S><S><T><S><F><K><Q><I><I><E><E><I><D><E><D><G><S><G><Q><I><E><F><S><E><F><L><Q><L><A><A><K><F><L><I><E><E><D><E><E><A><M><M><K><E><L><K><E><A><F><R><L><Y><D><K><E><G... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P21797 |
B3CLX6 | TSAD_WOLPP | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | unclassified Wolbachia | <M><K><T><I><L><A><I><E><T><S><C><D><E><T><A><V><A><I><V><N><S><D><K><Q><V><L><A><N><E><I><L><S><Q><V><E><H><K><K><C><G><G><V><I><P><E><I><A><S><R><A><H><M><K><H><L><S><G><L><I><K><S><A><M><E><K><S><N><L><N><F><C><D><L><D><A><I><A><A><T><S><G><P><G><L><I><G><G><L><I><I><G><T><M><M><A><K><A><I><A><H><V><T><Q><K><P><F><I... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | B3CLX6 |
Q6G1R3 | TSAD_BARHE | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Bartonella | <M><R><L><L><G><I><E><T><S><C><D><E><T><A><T><A><V><I><E><H><T><I><G><G><N><S><Q><I><L><S><N><I><V><W><S><Q><T><D><H><H><A><P><Y><G><G><V><V><P><E><I><A><A><R><A><H><V><E><I><L><D><E><L><I><L><K><A><L><R><D><A><H><T><K><L><K><D><I><D><A><I><A><V><T><N><G><P><G><L><I><G><G><L><L><V><G><V><M><S><A><K><A><L><S><L><A><T><G... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q6G1R3 |
A1R8Y7 | TYSY_PAEAT | Thymidylate synthase | Paenarthrobacter | <M><S><I><P><T><P><Y><E><D><L><L><R><D><V><M><A><N><G><T><H><K><S><D><R><T><G><T><G><T><R><S><V><F><G><R><Q><L><R><F><D><L><A><E><S><F><P><L><I><T><T><K><R><V><H><F><K><S><V><A><V><E><L><L><W><F><L><R><G><D><S><N><V><K><W><M><Q><D><Q><G><V><S><I><W><D><E><W><A><D><A><D><G><E><L><G><P><V><Y><G><V><Q><W><R><S><W><P><T><P... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | A1R8Y7 |
Q73S85 | Y4191_MYCPA | Putative S-adenosyl-L-methionine-dependent methyltransferase MAP_4191c | Mycobacterium avium complex (MAC) | <M><T><S><T><R><Y><E><G><D><T><W><D><L><A><S><S><V><G><V><T><A><T><M><V><A><A><A><R><A><M><A><T><R><A><D><N><P><L><I><N><D><L><F><A><E><P><L><V><K><A><V><G><V><D><L><L><S><R><L><A><G><G><E><L><D><P><A><E><L><N><D><V><H><D><G><A><A><G><S><A><G><A><M><S><R><M><A><D><N><M><A><V><R><T><K><F><F><D><E><F><F><L><N><A><T><K><A... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | Q73S85 |
A9MVX4 | TREA_SALPB | Alpha,alpha-trehalose glucohydrolase | Salmonella | <M><I><P><P><E><I><R><R><S><V><L><L><Q><K><A><I><K><L><A><L><A><G><T><L><L><T><F><A><S><F><S><A><T><A><A><D><P><S><S><D><T><E><T><P><Q><P><P><D><I><L><L><G><P><L><F><N><D><V><Q><N><A><K><L><F><P><D><Q><K><T><F><A><D><A><I><P><N><S><D><P><L><M><I><L><A><D><Y><R><M><Q><R><N><Q><S><G><F><D><L><R><H><F><V><D><V><N><F><T><L... | Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system.<BOP> | A9MVX4 |
G4ZHR2 | XEG1_PHYSP | Glycoside hydrolase family 12 protein XEG1 | Phytophthora | <M><K><G><F><F><A><G><V><V><A><A><A><T><L><A><V><A><S><A><G><D><Y><C><G><Q><W><D><W><A><K><S><T><N><Y><I><V><Y><N><N><L><W><N><K><N><A><A><A><S><G><S><Q><C><T><G><V><D><K><I><S><G><S><T><I><A><W><H><T><S><Y><T><W><T><G><G><A><A><T><E><V><K><S><Y><S><N><A><A><L><V><F><S><K><K><Q><I><K><N><I><K><S><I><P><T><K><M><K><Y><S... | Glycoside hydrolase that exhibits xyloglucanase activity . Acts as an important virulence factor during P.sojae infection but also acts as a pathogen-associated molecular pattern (PAMP) in soybean and solanaceous species, where it can trigger defense responses including cell death. XEG1-induced cell death can be suppre... | G4ZHR2 |
Q6KZ89 | UPPS_PICTO | Undecaprenyl pyrophosphate synthase | Picrophilus | <M><S><D><I><G><N><F><V><S><R><I><Y><E><S><K><L><L><E><E><I><K><K><H><P><V><P><G><H><L><G><I><I><T><D><G><N><R><R><Y><A><R><S><I><G><I><S><E><N><E><G><H><V><K><G><K><E><K><L><E><E><V><L><N><W><S><M><E><V><G><I><H><M><V><T><V><Y><A><F><S><T><E><N><F><K><R><K><S><D><E><V><N><F><L><F><N><L><I><N><D><A><F><I><D><L><L><N><D... | Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.<BOP> | Q6KZ89 |
Q78XR0 | TPC6A_MOUSE | Trafficking protein particle complex subunit 6A | Mus | <M><A><D><A><V><L><F><E><F><L><H><T><E><M><V><A><E><L><W><A><P><D><P><D><P><G><S><G><G><K><R><R><S><L><S><V><L><E><G><L><G><F><R><V><G><Q><A><L><G><E><R><L><P><L><E><T><P><A><F><R><E><E><L><D><A><L><K><F><L><C><R><D><L><W><A><A><M><F><Q><K><H><M><D><G><L><R><T><N><H><Q><G><T><Y><V><L><Q><D><N><S><F><P><L><L><V><T><M><G... | May play a role in vesicular transport during the biogenesis of melanosomes.<BOP> | Q78XR0 |
Q5L3H7 | UPPP_GEOKA | Undecaprenyl pyrophosphate phosphatase | Geobacillus thermoleovorans group | <M><H><W><M><E><L><W><K><A><I><I><L><G><M><V><E><G><L><T><E><F><A><P><V><S><S><T><G><H><M><I><M><V><D><D><L><W><L><K><S><T><E><F><L><G><K><Y><A><A><N><T><F><K><V><V><I><Q><L><G><S><I><L><A><A><V><V><V><F><K><D><R><F><L><D><L><L><G><V><R><G><R><H><P><G><G><H><P><R><L><N><L><I><H><V><I><I><G><L><L><P><A><G><V><L><G><V><L... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q5L3H7 |
Q1AUH8 | TPIS_RUBXD | Triose-phosphate isomerase | Rubrobacter | <M><A><G><E><R><R><P><L><M><A><A><N><W><K><M><N><K><T><V><R><E><A><Q><D><Y><M><A><A><L><L><P><R><V><A><D><L><A><G><E><V><D><V><A><V><F><A><P><F><T><C><L><S><E><V><A><R><M><A><E><G><S><G><V><L><A><G><A><Q><N><F><F><Y><E><D><S><G><A><Y><T><G><E><V><S><A><P><M><L><L><D><V><G><A><R><A><S><I><V><G><H><S><E><R><R><E><L><F><C... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q1AUH8 |
A8MK92 | THIE_ALKOO | Thiamine-phosphate pyrophosphorylase | Alkaliphilus | <M><K><Y><N><H><T><V><D><Y><G><L><Y><L><V><S><D><R><D><V><L><K><G><R><D><F><I><K><S><L><E><E><A><I><L><G><G><A><T><I><V><Q><L><R><E><K><E><A><S><S><L><E><F><Y><Q><L><A><L><K><A><K><A><L><T><E><K><Y><N><V><P><L><I><I><N><D><R><V><D><I><A><L><A><V><D><A><D><G><V><H><V><G><Q><S><D><L><P><A><H><I><V><R><S><M><I><G><Q><N><K... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A8MK92 |
G5CV46 | TPS31_SOLLC | Viridiflorene synthase TPS31 | Solanum subgen. Lycopersicon | <M><A><P><A><A><A><L><M><S><K><C><Q><E><E><E><E><I><V><R><P><V><A><D><F><S><P><S><L><W><G><D><R><F><H><S><F><S><L><D><N><Q><V><A><E><K><Y><V><E><E><I><E><T><L><K><E><Q><T><R><S><M><L><M><S><G><K><T><L><A><E><K><L><N><L><I><D><I><V><E><R><L><G><I><A><Y><H><F><E><K><Q><I><D><D><M><L><N><H><I><F><N><I><D><P><N><F><E><A><H... | Sesquiterpene synthase involved in the production of viridiflorene from (E,E)-farnesyl diphosphate (FPP) . Has no activity with (Z,Z)-FPP . Can act with a low efficiency as a monoterpene synthase with geranyl diphosphate as substrate .<BOP> | G5CV46 |
P35723 | YET1_YEAST | Endoplasmic reticulum transmembrane protein 1 | Saccharomyces | <M><S><L><Y><F><T><T><L><F><L><L><L><T><V><E><M><V><M><L><F><I><F><V><L><P><L><P><F><R><I><R><R><G><I><F><S><T><Y><N><Q><L><T><A><K><Q><Q><I><K><T><I><I><F><I><T><G><C><L><V><G><L><L><F><I><D><S><W><K><R><S><Q><I><R><V><S><L><Y><H><N><D><N><S><G><S><I><G><S><S><A><V><T><P><I><Q><A><L><A><S><R><A><Y><N><Q><R><N><M><Y><I... | May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.<BOP> | P35723 |
Q9TS87 | TAGL_BOVIN | Smooth muscle protein 22-alpha | Bos | <M><A><N><K><G><P><S><Y><G><M><S><R><E><V><Q><S><K><I><E><K><K><Y><D><E><E><L><E><E><R><L><V><E><W><I><V><M><Q><C><G><P><D><V><G><R><P><D><R><G><R><L><G><F><Q><V><W><L><K><N><G><V><I><L><S><K><L><V><N><S><L><Y><P><D><G><S><K><P><V><K><V><P><E><N><P><P><S><M><V><F><K><Q><M><E><Q><V><A><Q><F><L><K><A><A><E><D><Y><G><V><T... | Actin cross-linking/gelling protein.<BOP> | Q9TS87 |
B7GP48 | TILS_BIFLS | tRNA(Ile)-lysidine synthetase | Bifidobacterium | <M><A><Y><S><A><R><L><R><K><A><V><G><A><V><R><A><T><L><S><A><V><E><L><C><D><V><Q><A><P><E><F><A><Q><H><G><D><H><A><V><A><A><D><A><P><L><V><L><V><A><C><S><G><G><R><D><S><M><A><L><A><A><V><S><H><I><V><C><T><S><M><G><V><R><C><G><A><V><I><V><D><H><G><L><Q><E><G><S><E><Q><V><A><G><E><A><A><N><R><C><R><A><L><G><L><G><P><V><I... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | B7GP48 |
Q27987 | TSHR_BOVIN | Thyroid-stimulating hormone receptor | Bos | <M><R><P><T><P><L><L><R><L><A><L><F><L><V><L><P><S><S><L><G><G><E><R><C><P><S><P><P><C><E><C><R><Q><E><D><D><F><R><V><T><C><K><D><I><Q><S><I><P><S><L><P><P><S><T><Q><T><L><K><F><I><E><T><H><L><K><T><I><P><S><R><A><F><S><N><L><P><N><I><S><R><I><Y><L><S><I><D><A><T><L><Q><Q><L><E><S><H><S><F><Y><N><L><S><K><V><T><H><I><E... | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.<BOP... | Q27987 |
Q9NP84 | TNR12_HUMAN | Tweak-receptor | Homo | <M><A><R><G><S><L><R><R><L><L><R><L><L><V><L><G><L><W><L><A><L><L><R><S><V><A><G><E><Q><A><P><G><T><A><P><C><S><R><G><S><S><W><S><A><D><L><D><K><C><M><D><C><A><S><C><R><A><R><P><H><S><D><F><C><L><G><C><A><A><A><P><P><A><P><F><R><L><L><W><P><I><L><G><G><A><L><S><L><T><F><V><L><G><L><L><S><G><F><L><V><W><R><R><C><R><R><R... | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.<BOP> | Q9NP84 |
Q3IRZ2 | URED_NATPD | Urease accessory protein UreD | Natronomonas | <M><S><A><V><P><D><A><F><Q><R><Y><G><A><E><S><L><A><Q><A><P><A><F><G><P><G><K><D><G><V><F><E><A><T><L><A><R><T><G><D><R><D><T><R><L><L><R><D><Y><T><K><V><P><Y><H><L><T><G><T><L><D><T><D><P><A><P><G><L><T><T><L><C><L><Q><E><P><T><G><G><V><A><Q><G><D><R><H><S><I><T><V><T><A><R><E><G><A><R><A><R><V><T><T><Q><S><A><T><K><V... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | Q3IRZ2 |
B1LQ65 | TRUD_ECOSM | tRNA-uridine isomerase D | Escherichia | <M><I><E><F><D><N><L><T><Y><L><H><G><K><P><Q><G><T><G><L><L><K><A><N><P><E><D><F><V><V><V><E><D><L><G><F><E><P><D><G><E><G><E><H><I><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><L><C><A><R><V><P><G><K><E><M><P><D><L><S><A><F><Q><L><E... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | B1LQ65 |
Q9I750 | TSSA1_PSEAE | Type VI secretion system component TssA1 | Pseudomonas | <M><L><D><V><P><V><L><L><A><A><V><S><P><D><S><P><C><G><D><D><L><E><Y><D><A><A><F><L><E><L><E><R><I><A><Q><G><Q><P><E><R><Q><M><G><D><A><V><L><P><A><E><P><P><E><W><P><R><V><R><A><L><A><S><E><L><F><G><R><S><K><D><L><R><V><A><N><L><L><L><Q><S><N><V><A><L><D><G><L><D><G><L><A><D><G><L><L><L><V><R><E><L><L><G><Q><Y><W><D><G... | Core component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species. Forms a dodecameric ring-shaped structure located at one end of the T6SS sheath. May properly attach the pre-assembled sheath onto the baseplate and/or stabilize the ... | Q9I750 |
Q5DP50 | TEX24_MOUSE | Testis-specific factor 1 | Mus | <M><G><S><Q><S><L><N><S><T><F><L><K><V><R><R><L><S><L><I><S><S><N><E><R><L><L><G><Q><T><S><G><L><A><T><G><S><R><L><V><T><Q><E><V><D><D><L><R><V><I><P><G><S><R><P><D><L><D><D><H><Q><P><Q><C><S><L><A><E><L><P><S><T><A><H><G><K><R><K><P><G><H><L><P><R><L><R><S><S><A><V><K><G><H><A><P><D><P><N><P><S><L><S><I><V><S><K><R><I... | Nuclear factor which might have a role in spermatogenesis.<BOP> | Q5DP50 |
Q5P6J5 | THIE_AROAE | Thiamine-phosphate pyrophosphorylase | Aromatoleum | <M><P><D><T><R><L><R><G><L><Y><L><I><T><P><D><S><P><D><T><T><T><L><V><A><Q><V><E><R><A><L><R><G><Q><P><A><L><L><Q><Y><R><S><K><Q><R><D><A><A><L><R><L><G><Q><A><R><Q><I><A><A><L><C><R><E><A><G><V><P><F><I><V><N><D><S><L><E><L><A><L><A><T><D><A><D><G><V><H><L><G><R><E><D><G><D><L><D><A><A><R><R><A><L><G><P><G><R><I><L><G... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q5P6J5 |
Q9JLT2 | TREA_MOUSE | Alpha,alpha-trehalose glucohydrolase | Mus | <M><T><W><E><L><H><L><L><L><L><L><G><L><G><L><R><S><Q><E><A><L><P><P><P><C><E><S><Q><I><Y><C><H><G><E><L><L><H><Q><V><Q><M><A><Q><L><Y><Q><D><D><K><Q><F><V><D><M><S><L><A><T><S><P><D><E><V><L><Q><K><F><S><E><L><A><T><V><H><N><H><S><I><P><K><E><Q><L><Q><E><F><V><Q><S><H><F><Q><P><V><G><Q><E><L><Q><S><W><T><P><E><D><W><K... | Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.<BOP> | Q9JLT2 |
D7PI00 | VRTR1_PENAE | Viridicatumtoxin synthesis protein R1 | Penicillium | <M><E><D><T><T><E><T><T><E><T><T><D><T><T><A><V><S><R><L><V><P><L><A><P><A><P><A><R><A><P><S><M><D><A><V><N><G><S><F><D><S><E><L><T><T><A><R><R><F><N><C><Q><S><C><V><R><K><K><I><K><C><N><R><A><V><P><T><C><A><S><C><S><K><A><K><L><H><C><V><Y><Q><S><R><P><P><R><K><R><K><R><S><R><G><E><E><D><V><Y><E><R><L><A><Q><Y><E><R><I... | Probable transcription factor that regulates expression of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system .<BOP> | D7PI00 |
B4RE94 | YIDD_PHEZH | Putative membrane protein insertion efficiency factor | Phenylobacterium | <M><N><L><Y><E><S><C><V><R><G><A><L><R><A><Y><K><L><T><L><S><P><L><I><G><R><Q><C><R><F><F><P><T><C><S><E><Y><A><A><E><A><L><I><G><H><G><P><V><R><G><S><W><L><T><V><R><R><L><C><R><C><H><P><W><G><P><S><G><W><D><P><P><P><P><P><R><R><K><G><A><K><W><T><C><E><T> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | B4RE94 |
Q15629 | TRAM1_HUMAN | Translocating chain-associated membrane protein 1 | Homo | <M><A><I><R><K><K><S><T><K><S><P><P><V><L><S><H><E><F><V><L><Q><N><H><A><D><I><V><S><C><V><A><M><V><F><L><L><G><L><M><F><E><I><T><A><K><A><S><I><I><F><V><T><L><Q><Y><N><V><T><L><P><A><T><E><E><Q><A><T><E><S><V><S><L><Y><Y><Y><G><I><K><D><L><A><T><V><F><F><Y><M><L><V><A><I><I><I><H><A><V><I><Q><E><Y><M><L><D><K><I><N><R... | (Microbial infection) In case of cytomegalovirus infection, participates in US2- and US11-mediated ER-to-cytosol retrotranslocation and subsequent degradation of major histocompatibility complex (MHC) class I heavy chains, thereby decreasing the immune detection by cytotoxic T-cells.<BOP> | Q15629 |
B8D9V4 | TUSC_BUCA5 | tRNA 2-thiouridine synthesizing protein C | Buchnera | <M><K><M><V><A><F><V><F><S><H><A><P><H><G><I><S><L><G><R><E><G><L><D><A><I><F><S><I><S><L><I><F><K><K><I><S><V><F><F><I><G><D><G><V><L><Q><L><I><K><N><Q><Q><P><E><H><I><L><A><R><N><Y><T><S><S><F><S><I><L><S><L><Y><N><I><K><D><L><Y><C><C><K><A><S><L><L><E><R><G><L><N><N><N><N><N><F><I><L><N><I><D><V><L><D><S><Y><N><L><R... | Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.<BOP> | B8D9V4 |
A3N3S3 | TATA_ACTP2 | Sec-independent protein translocase protein TatA | Actinobacillus | <M><G><G><I><S><I><W><Q><L><L><I><I><V><A><I><I><V><L><L><F><G><T><K><K><L><R><T><L><G><T><D><L><G><E><S><V><K><G><F><K><K><A><M><A><D><D><K><S><Q><P><Q><D><A><S><F><E><K><V><E><A><K><E><A><A><S><T><E><Q><K><A><K><E><K><E><Q><A> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | A3N3S3 |
Q14AK4 | ZDH11_MOUSE | Zinc finger DHHC domain-containing protein 11 | Mus | <M><K><E><M><N><I><C><G><I><N><K><N><W><V><L><P><E><A><Q><E><N><N><V><K><K><F><L><P><R><P><L><S><R><V><N><G><W><S><P><P><L><H><S><F><Q><A><I><S><W><I><T><Y><L><A><M><S><I><V><T><F><G><I><F><I><P><F><L><P><Y><S><W><K><Y><A><A><N><I><V><M><G><G><V><F><I><F><H><L><I><V><H><L><I><A><I><T><I><D><P><A><D><T><N><V><R><L><K><K... | Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response . Functions as an adapter that recruits IRF3 to STING1 to promote the activation of that key transcriptional regulator of type I interferon (IFN)-dependent immune response .<BOP> | Q14AK4 |
P12458 | TBB2_PHYPO | Tubulin beta-major chain | Physarum | <M><R><E><I><V><H><V><Q><V><G><Q><C><G><N><Q><V><G><A><K><F><W><E><V><V><S><E><E><H><G><I><D><S><A><G><T><Y><K><G><D><T><D><L><Q><L><E><R><I><N><V><Y><Y><N><E><V><A><G><S><K><Y><V><P><R><A><V><L><V><D><L><E><P><G><V><L><D><S><I><R><A><S><S><I><G><S><M><F><R><P><D><N><F><T><H><A><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | This is the major beta tubulin of mitotic spindle.<BOP> | P12458 |
Q5WH87 | THIE_ALKCK | Thiamine-phosphate pyrophosphorylase | Alkalihalobacillus | <M><K><P><F><R><L><Y><A><I><T><G><E><E><F><H><P><G><R><D><V><V><E><V><M><E><E><A><I><Q><G><G><V><D><I><I><Q><L><R><D><K><T><S><S><K><K><A><V><L><E><K><A><R><R><L><K><K><L><A><A><D><Y><G><I><P><F><I><V><N><D><H><I><D><V><A><L><A><V><D><A><S><G><V><H><V><G><Q><D><D><L><P><L><P><E><V><R><K><L><L><G><P><D><K><I><I><G><V><S... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q5WH87 |
P27156 | XYLB_STRRU | Xylulose kinase | Streptomyces pseudogriseolus group | <M><S><A><A><E><G><P><L><V><V><G><V><D><T><S><T><Q><S><T><K><A><L><V><V><D><V><A><T><G><R><V><V><A><S><G><Q><A><P><H><T><V><T><S><G><A><G><R><E><S><D><P><R><Q><W><W><D><A><L><C><E><A><L><R><Q><C><G><E><A><A><H><E><A><A><A><V><S><I><G><G><Q><Q><H><G><L><V><T><L><D><G><H><G><E><P><V><R><P><A><L><L><W><N><D><V><R><S><A><P... | Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.<BOP> | P27156 |
A7ZIN1 | YBAB_ECO24 | Nucleoid-associated protein YbaB | Escherichia | <M><F><G><K><G><G><L><G><N><L><M><K><Q><A><Q><Q><M><Q><E><K><M><Q><K><M><Q><E><E><I><A><Q><L><E><V><I><G><E><S><G><A><G><L><V><K><V><T><I><N><G><A><H><N><C><R><R><V><E><I><D><P><S><L><L><E><D><D><K><E><M><L><E><D><L><V><A><A><A><F><N><D><A><A><R><R><I><E><E><T><Q><K><E><K><M><A><S><V><S><S><G><M><Q><L><P><P><G><F><K><M... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | A7ZIN1 |
Q2T7H3 | TRUA_BURTA | tRNA-uridine isomerase I | pseudomallei group | <M><R><I><A><L><G><I><Q><Y><D><G><A><A><F><C><G><W><Q><S><Q><P><H><G><K><T><V><Q><D><A><L><E><R><A><L><A><E><F><A><Q><T><S><L><H><T><T><V><A><G><R><T><D><T><G><V><H><G><L><G><Q><V><V><H><F><D><T><D><L><D><R><A><D><F><S><W><V><R><G><T><N><A><F><L><P><S><T><V><A><V><Q><W><A><K><P><M><P><D><T><F><H><A><R><F><A><A><F><E><R... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q2T7H3 |
Q8XXC7 | UPP_RALSO | UPRTase | Ralstonia | <M><T><Q><D><P><R><F><P><N><L><F><I><L><N><H><P><L><I><Q><H><K><L><T><H><M><R><D><K><D><T><S><T><R><T><F><R><E><L><L><R><E><I><T><L><L><M><G><Y><E><I><T><R><N><L><P><L><T><T><R><H><I><E><T><P><M><G><P><M><D><A><P><V><I><A><G><R><K><L><A><V><V><P><V><L><R><A><G><V><G><M><S><D><G><L><L><E><L><I><P><S><A><R><V><G><H><I><G... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | Q8XXC7 |
A6TTD6 | XPT_ALKMQ | Xanthine phosphoribosyltransferase | Alkaliphilus | <M><E><L><L><K><E><Q><I><R><E><V><A><R><V><E><K><G><N><V><L><K><V><D><S><F><L><N><H><Q><L><D><I><P><L><L><N><E><I><G><K><E><L><K><K><R><F><Q><G><E><K><V><D><K><I><L><T><A><E><V><S><G><I><A><I><A><A><I><A><A><Q><Y><F><N><V><P><V><V><F><A><K><K><T><Q><S><K><N><L><D><Q><D><T><Y><E><G><E><V><Y><S><Y><T><K><G><Q><A><Y><K><I... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | A6TTD6 |
B9JEG8 | TATA_AGRRK | null | Agrobacterium tumefaciens complex | <M><G><S><L><S><I><W><H><W><L><I><V><L><A><I><A><L><L><L><F><G><R><G><K><I><P><E><L><M><G><D><V><A><K><G><I><K><S><F><K><K><G><M><N><D><D><E><E><T><P><P><P><A><Q><S><T><T><S><R><T><V><E><H><K><A><D><E><S><K> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | B9JEG8 |
Q5KVB5 | UVRB_GEOKA | Excinuclease ABC subunit B | Geobacillus thermoleovorans group | <M><E><G><R><F><Q><L><V><A><P><Y><E><P><Q><G><D><Q><P><Q><A><I><A><K><L><V><D><G><L><R><R><G><V><K><H><Q><T><L><L><G><A><T><G><T><G><K><T><F><T><I><S><N><V><I><A><Q><V><N><K><P><T><L><V><I><A><H><N><K><T><L><A><G><Q><L><Y><S><E><L><K><E><F><F><P><H><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><Q><T><D><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q5KVB5 |
O20030 | YCF4_CHLRE | Photosystem I assembly protein Ycf4 | Chlamydomonas | <M><T><Q><N><N><I><L><I><R><R><Y><I><I><V><G><E><R><R><F><S><N><Y><W><W><A><I><V><I><F><L><G><S><C><G><F><L><A><T><G><I><C><S><Y><L><G><I><P><N><W><L><S><L><L><N><I><G><T><T><F><S><S><E><T><E><T><L><A><S><G><I><V><P><F><F><P><Q><G><L><L><M><S><F><Y><G><S><L><G><F><L><L><S><I><Y><W><S><L><L><I><F><W><N><V><G><G><G><F><N... | Seems to be required for the assembly of the photosystem I complex.<BOP> | O20030 |
Q8Z3H9 | TRUB_SALTI | tRNA-uridine isomerase | Salmonella | <M><S><R><P><R><R><R><G><R><D><I><H><G><V><L><L><L><D><K><P><Q><G><M><S><S><N><D><V><L><Q><K><V><K><R><I><Y><N><A><N><R><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><Y><L><L><D><S><D><K><R><Y><R><V><I><A><R><L><G><Q><R><T><D><T><S><D><A><D><G><Q><I><V><Q><E><R><P><V><T><F><S><A><E><Q... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q8Z3H9 |
Q9BGN4 | TSHR_FELCA | Thyroid-stimulating hormone receptor | Felis | <M><R><Q><T><P><L><L><Q><L><A><L><L><L><S><L><P><R><S><L><G><G><K><G><C><P><S><P><P><C><E><C><H><Q><E><D><D><F><R><V><T><C><K><D><I><H><R><I><P><S><L><P><P><S><T><Q><T><L><K><F><I><E><T><H><L><K><T><I><P><S><R><A><F><S><N><L><P><N><I><S><R><I><Y><L><S><I><D><A><T><L><Q><R><L><E><S><H><S><F><Y><N><L><S><K><M><T><H><I><E... | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.<BOP... | Q9BGN4 |
P27679 | TRI5_GIBPU | Sesquiterpene cyclase | Fusarium | <M><E><N><F><P><T><E><Y><F><L><N><T><S><V><R><L><L><E><Y><I><R><Y><R><D><S><N><Y><T><R><E><E><R><I><E><N><L><H><Y><A><Y><N><K><A><A><H><H><F><A><Q><P><R><Q><Q><Q><L><L><K><V><D><P><K><R><L><Q><A><S><L><Q><T><I><V><G><M><V><V><Y><S><W><A><K><V><S><K><E><C><M><A><D><L><S><I><H><Y><T><Y><T><L><V><L><D><D><S><S><D><D><P><Y... | TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP> | P27679 |
Q39PQ8 | YIDC_GEOMG | Membrane protein YidC | Geobacter | <M><E><K><R><A><L><I><A><V><I><L><S><I><V><F><F><Y><G><Y><S><A><L><F><P><P><P><K><K><E><A><P><A><P><S><A><Q><Q><A><V><T><G><S><Q><P><G><A><P><Q><A><S><V><A><A><V><P><A><P><S><P><V><P><A><A><A><V><K><A><Q><Q><K><E><I><A><V><E><T><P><D><Y><T><A><V><F><S><T><Q><G><G><S><L><T><R><L><V><L><K><K><Y><R><E><T><A><D><L><T><G><K... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | Q39PQ8 |
Q328K4 | ULAA_SHIDS | null | Shigella | <M><E><I><L><Y><N><I><F><T><V><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><N><Y><A><S><M><M><A><T><I><D><R><M><G><D><A><Y><S><W><V><G><Y><A... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | Q328K4 |
A1KB60 | THIE_AZOSB | Thiamine-phosphate pyrophosphorylase | Azoarcus | <M><G><E><R><I><R><G><L><Y><L><V><T><P><D><A><A><D><S><A><T><L><L><A><S><V><E><R><V><L><P><A><R><P><A><L><L><Q><Y><R><N><K><L><A><D><P><L><R><Q><L><D><E><A><R><S><L><R><Q><L><C><S><S><A><G><V><P><L><I><I><N><D><D><V><A><L><A><R><A><V><A><A><D><G><V><H><L><G><R><D><D><G><S><P><A><A><A><R><A><V><L><G><A><D><A><L><I><G><V... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A1KB60 |
Q880X7 | UVRC_PSESM | Excinuclease ABC subunit C | Pseudomonas | <M><T><Q><T><F><D><P><S><A><F><L><A><T><C><S><G><R><P><G><V><Y><R><M><F><D><A><D><A><T><L><L><Y><V><G><K><A><K><N><L><K><K><R><L><A><S><Y><F><R><K><T><G><H><A><P><K><T><G><A><L><V><A><R><I><A><Q><I><E><T><T><I><T><N><N><E><T><E><A><L><L><L><E><Q><T><L><I><K><E><W><R><P><P><Y><N><I><L><L><R><D><D><K><S><Y><P><Y><V><F><L... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q880X7 |
P28274 | URA7_YEAST | UTP--ammonia ligase 1 | Saccharomyces | <M><K><Y><V><V><V><S><G><G><V><I><S><G><I><G><K><G><V><L><A><S><S><T><G><M><L><M><K><T><L><G><L><K><V><T><S><I><K><I><D><P><Y><M><N><I><D><A><G><T><M><S><P><L><E><H><G><E><C><F><V><L><D><D><G><G><E><T><D><L><D><L><G><N><Y><E><R><Y><L><G><V><T><L><T><K><D><H><N><I><T><T><G><K><I><Y><S><H><V><I><A><K><E><R><K><G><D><Y><L... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.<BOP> | P28274 |
A4JCS0 | UVRC_BURVG | Excinuclease ABC subunit C | Burkholderia cepacia complex | <M><T><S><P><E><A><A><D><T><P><F><E><P><K><K><I><L><A><Q><L><P><H><M><P><G><V><Y><R><Y><Y><D><A><T><G><A><V><L><Y><V><G><K><A><R><D><L><K><K><R><V><S><S><Y><F><T><K><T><Q><L><S><P><R><I><A><M><M><V><T><R><I><A><R><I><E><T><T><V><T><R><S><E><A><E><A><L><L><L><E><N><N><L><I><K><A><L><A><P><R><Y><N><I><L><F><R><D><D><K><S... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | A4JCS0 |
C5A338 | VATD_THEGJ | V-ATPase subunit D | Thermococcus | <M><A><E><L><L><N><V><K><P><T><R><M><E><L><L><N><L><K><R><R><I><Q><L><A><K><K><G><H><K><L><L><K><D><K><Q><D><A><L><I><M><E><F><F><T><I><Y><D><E><A><L><Q><L><R><R><E><L><N><E><K><M><G><V><A><F><E><T><L><T><R><A><Q><I><E><A><G><T><L><P><L><R><E><A><A><L><A><V><K><P><N><K><E><V><E><I><K><R><R><N><V><M><G><V><S><V><P><L><I... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | C5A338 |
A3CK49 | VATB_STRSV | V-ATPase subunit B | Streptococcus | <M><S><V><I><K><E><Y><R><T><V><S><E><V><V><G><P><L><M><I><V><D><Q><V><A><G><V><H><F><N><E><L><V><E><I><Q><L><H><D><G><S><K><R><Q><G><Q><V><L><E><V><Q><E><D><K><A><M><V><Q><L><F><E><G><S><S><G><I><N><L><E><K><A><K><V><R><F><T><G><R><P><L><E><L><P><V><S><E><D><M><V><G><R><I><F><N><G><M><G><K><P><I><D><G><G><P><A><I><L><P... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.<BOP> | A3CK49 |
P43348 | TCTP_RABIT | Translationally-controlled tumor protein | Oryctolagus | <M><I><I><Y><R><D><L><I><S><H><D><E><M><F><S><D><I><Y><K><I><R><E><I><A><G><G><L><C><L><E><V><E><G><K><M><V><S><R><T><E><G><N><I><D><D><S><L><I><G><G><N><A><S><A><E><G><P><E><G><E><G><T><E><S><T><V><I><T><G><V><D><I><V><M><N><H><H><L><Q><E><T><S><F><T><K><E><A><Y><K><K><Y><I><K><D><Y><M><K><S><I><K><G><K><L><E><E><Q><R... | Involved in calcium binding and microtubule stabilization.<BOP> | P43348 |
O59490 | XERA_PYRHO | Tyrosine recombinase XerA | Pyrococcus | <M><K><E><R><E><E><I><V><N><S><D><I><L><E><E><F><A><T><Y><L><E><L><E><G><K><S><K><N><T><I><R><M><Y><T><Y><Y><L><S><K><F><F><E><E><G><Y><S><P><T><A><R><D><A><L><K><F><L><A><K><L><R><K><S><G><Y><S><I><R><S><L><N><L><V><I><Q><A><L><K><S><Y><F><K><F><E><G><L><D><S><E><A><E><K><L><K><N><P><K><I><P><K><S><L><P><K><S><L><T><E... | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.<BOP> | O59490 |
Q28VU8 | UPPP_JANSC | Undecaprenyl pyrophosphate phosphatase | unclassified Jannaschia | <M><S><L><F><T><L><F><L><L><A><L><V><Q><G><I><T><E><F><L><P><I><S><S><S><G><H><L><I><L><L><P><N><L><L><G><I><E><D><Q><G><Q><A><I><D><V><A><V><H><V><G><T><L><G><A><V><I><L><Y><F><W><R><D><V><K><A><A><I><A><G><T><P><R><L><L><T><G><R><I><D><T><P><G><A><K><L><A><F><L><L><I><I><A><T><I><P><V><I><I><F><G><L><F><L><E><V><T><G... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q28VU8 |
Q8IN42 | TOTZ_DROME | Protein Turandot Z | Sophophora | <M><Y><F><A><I><R><L><S><F><V><L><A><V><L><I><C><L><T><G><N><G><S><A><R><M><L><D><A><D><R><N><R><L><Q><Q><L><Q><I><R><S><Q><Q><S><A><D><A><N><T><Q><V><D><I><A><Y><E><V><I><G><I><Y><D><K><Y><K><G><Q><G><G><S><N><V><L><R><E><A><Q><L><N><S><Q><V><N><D><F><K><R><K><T><M><V><I><D><G><V><P><A><Q><G><G><V><W><G><I><L><G><A><I... | A humoral factor that may play a role in stress tolerance.<BOP> | Q8IN42 |
B8NM70 | USTYB_ASPFN | Ustiloxin B biosynthesis protein Yb | Aspergillus subgen. Circumdati | <M><P><S><D><G><N><H><L><T><R><S><T><G><G><N><G><F><I><A><V><N><Q><T><E><R><Y><T><L><P><P><P><I><K><Q><L><A><L><E><G><Q><D><P><R><T><D><N><P><G><T><D><G><T><G><A><V><H><I><C><K><D><F><D><G><I><L><A><W><A><D><S><R><R><L><V><D><A><K><H><N> | Oxidase; part of the gene cluster that mediates the biosynthesis of the secondary metabolite ustiloxin B, an antimitotic tetrapeptide . First, ustA is processed by the subtilisin-like endoprotease Kex2 that is outside the ustiloxin B gene cluster, at the C-terminal side of Arg-Lys, after transfer to Golgi apparatus thr... | B8NM70 |
Q3KP31 | ZN791_HUMAN | Zinc finger protein 791 | Homo | <M><D><S><V><A><F><E><D><V><S><V><S><F><S><Q><E><E><W><A><L><L><A><P><S><Q><K><K><L><Y><R><D><V><M><Q><E><T><F><K><N><L><A><S><I><G><E><K><W><E><D><P><N><V><E><D><Q><H><K><N><Q><G><R><N><L><R><S><H><T><G><E><R><L><C><E><G><K><E><G><S><Q><C><A><E><N><F><S><P><N><L><S><V><T><K><K><T><A><G><V><K><P><Y><E><C><T><I><C><G><K... | May be involved in transcriptional regulation.<BOP> | Q3KP31 |
B0Y4Q5 | TVP38_ASPFC | Golgi apparatus membrane protein tvp38 | Aspergillus subgen. Fumigati | <M><P><A><D><Y><T><S><T><A><R><A><L><S><L><P><M><S><P><A><E><S><L><S><P><A><E><E><D><T><R><P><L><W><S><H><L><A><S><S><R><R><N><T><A><S><P><S><V><R><E><S><T><G><L><R><D><Q><V><V><N><Q><A><T><K><M><L><R><R><T><K><K><T><W><R><R><L><T><F><W><Q><R><I><G><A><I><G><A><A><L><L><A><I><L><L><G><L><S><F><M><I><F><T><G><Q><V><F><F... | Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP> | B0Y4Q5 |
Q96493 | UFOG_GENTR | UDP-glucose flavonoid 3-O-glucosyltransferase | Gentiana | <M><S><P><V><S><H><V><A><V><L><A><F><P><F><G><T><H><A><A><P><L><L><T><L><V><N><R><L><A><A><S><A><P><D><I><I><F><S><F><F><S><T><S><S><S><I><T><T><I><F><S><P><T><N><L><I><S><I><G><S><N><I><K><P><Y><A><V><W><D><G><S><P><E><G><F><V><F><S><G><N><P><R><E><P><I><E><Y><F><L><N><A><A><P><D><N><F><D><K><A><M><K><K><A><V><E><D><T... | In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments . Anthocyanidins are the preferred substrates, while flavonols are only a minor substrate in vitro .<BOP> | Q96493 |
Q2SUI1 | TRPD_BURTA | Anthranilate phosphoribosyltransferase | pseudomallei group | <M><T><I><T><P><Q><E><A><L><Q><R><T><I><E><H><R><E><I><F><H><D><E><M><L><H><L><M><R><L><I><M><R><G><D><M><S><P><V><M><A><A><A><I><I><T><G><L><R><V><K><K><E><T><I><G><E><I><T><A><A><A><T><V><M><R><E><F><A><R><H><V><E><V><E><D><N><A><N><F><V><D><I><V><G><T><G><G><D><G><S><H><T><F><N><I><S><T><A><T><M><F><V><A><A><A><A><G... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q2SUI1 |
P38669 | TBA2_NEUCR | Tubulin alpha-B chain | Neurospora | <M><R><E><I><I><S><L><N><V><G><Q><A><G><C><Q><I><A><N><S><C><W><E><L><Y><C><L><E><H><G><I><Q><P><D><G><Y><L><T><E><E><R><K><A><A><D><P><D><H><G><F><S><T><F><F><S><E><T><G><N><G><K><Y><V><P><R><T><I><Y><A><D><L><E><P><N><V><I><D><E><V><R><T><G><A><Y><R><G><L><F><H><P><E><H><M><I><S><G><K><E><D><A><S><N><N><Y><A><R><G><H... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | P38669 |
B4STS7 | TRMB_STRM5 | tRNA(m7G46)-methyltransferase | Stenotrophomonas maltophilia group | <M><T><N><P><F><D><S><A><G><S><K><A><P><P><K><P><F><T><V><S><E><G><R><R><E><V><R><S><F><V><L><R><Q><G><R><F><T><P><A><Q><Q><R><A><F><D><E><R><W><P><R><F><G><I><D><Y><N><G><Q><P><R><D><L><D><A><T><F><G><R><P><A><H><K><V><L><E><I><G><F><G><N><G><A><A><M><R><F><A><A><Q><H><D><P><S><R><D><Y><I><G><I><E><V><H><A><P><G><V><G... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | B4STS7 |
P61410 | THIE_BACC1 | Thiamine-phosphate pyrophosphorylase | Bacillus cereus group | <M><S><R><I><S><K><A><E><M><S><R><L><L><S><V><Y><F><I><M><G><S><N><N><C><T><K><D><P><L><Q><I><L><K><D><A><L><E><G><G><I><T><I><F><Q><F><R><E><K><G><E><G><A><L><T><G><E><E><R><I><C><F><A><K><E><L><Q><A><I><C><K><E><Y><G><V><P><F><I><V><N><D><D><V><E><L><A><L><E><L><D><A><D><G><V><H><V><G><Q><E><D><E><G><I><T><S><V><R><E... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | P61410 |
Q07402 | UREF_BACSB | Urease accessory protein UreF | Bacillus | <M><N><R><L><L><S><L><F><Q><L><C><D><S><N><F><P><S><G><S><F><S><H><S><F><G><L><E><T><Y><I><Q><E><K><V><I><T><D><K><E><S><F><K><N><A><I><S><V><Y><I><R><K><Q><L><F><F><T><E><G><L><A><C><I><L><A><Y><E><A><M><E><K><N><E><P><S><A><L><V><E><L><D><H><I><L><F><A><S><N><V><A><Q><E><T><R><S><G><N><Q><R><M><G><E><R><M><A><K><L><C... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | Q07402 |
Q5L5I5 | TAL_CHLAB | Transaldolase | Chlamydia | <M><S><S><Q><F><E><Q><L><K><L><L><S><V><L><V><C><D><T><G><D><P><E><L><V><K><S><S><E><S><Q><D><A><T><T><N><P><S><L><I><L><K><V><A><Q><E><P><K><Y><Q><E><L><L><T><E><A><I><A><W><G><I><R><Q><N><G><D><D><V><Q><T><L><T><F><V><L><D><K><I><Q><V><N><F><G><L><E><I><L><K><H><I><P><G><R><V><S><L><E><I><D><A><R><L><S><F><N><T><E><A... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q5L5I5 |
P9WIZ6 | Y3131_MYCTO | Putative NAD(P)H nitroreductase MT3217 | Mycobacterium tuberculosis complex | <M><T><A><A><V><D><G><K><G><P><A><A><M><N><T><H><F><P><D><A><E><T><V><R><T><V><L><T><L><A><V><R><A><P><S><I><H><N><T><Q><P><W><R><W><R><V><C><P><T><S><L><E><L><F><S><R><P><D><M><Q><L><R><S><T><D><P><D><G><R><E><L><I><L><S><C><G><V><A><L><H><H><C><V><V><A><L><A><S><L><G><W><Q><A><K><V><N><R><F><P><D><P><K><D><R><C><H><L... | Stimulates pro-inflammatory cytokine expression via TLR2 signaling pathway. Activation of TLR2 results in the phosphorylation and activation of NF-kappa-B. Also induces TLR2 expression. May influence the innate immune responses to facilitate the survival of M.tuberculosis in the granulomatous microenvironment.<BOP> | P9WIZ6 |
Q07748 | THI13_YEAST | Thiamine pyrimidine synthase | Saccharomyces | <M><S><T><D><K><I><T><F><L><L><N><W><Q><P><T><P><Y><H><I><P><I><F><L><A><Q><T><K><G><Y><F><K><E><Q><G><L><D><I><A><I><L><E><P><T><N><P><S><D><V><T><E><L><I><G><S><G><K><V><D><M><G><L><K><A><M><I><H><T><L><A><A><K><A><R><G><F><P><V><T><S><V><A><S><L><L><D><E><P><F><T><G><V><L><Y><L><K><G><S><G><I><T><E><D><F><Q><S><L><K... | Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme... | Q07748 |
Q9ZRX0 | TCTP_PSEMZ | Translationally-controlled tumor protein homolog | Pseudotsuga | <M><I><V><Y><Q><D><L><L><S><G><D><E><L><L><S><D><S><F><P><Y><K><E><L><Y><N><G><V><L><W><E><V><E><G><K><W><V><V><Q><G><A><V><D><V><D><I><G><A><N><P><S><A><E><G><G><D><E><E><G><V><K><I><R><L><V><K><V><V><D><I><V><D><T><F><R><L><Q><E><Q><P><P><F><D><K><K><Q><F><L><G><F><I><K><R><Y><I><K><N><L><A><T><K><L><S><E><E><R><Q><A... | Involved in calcium binding and microtubule stabilization.<BOP> | Q9ZRX0 |
Q03LR5 | TRHO_STRTD | tRNA hydroxylation protein O | Streptococcus | <M><A><K><P><I><R><V><L><L><Y><Y><K><Y><V><P><I><E><N><A><E><Q><F><A><A><D><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><V><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><Y><V><H><S><L><P><G><M><E><D><L><W><F><K><I><D><E><E><E><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><N><F><D... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | Q03LR5 |
Q3SQ36 | TYSY_NITWN | Thymidylate synthase | Nitrobacter | <M><N><Q><Y><H><D><L><L><E><R><I><L><G><E><G><T><E><K><H><D><R><T><G><T><G><T><L><S><V><F><G><H><Q><M><R><F><D><L><A><S><G><F><P><M><L><T><T><K><K><L><P><F><R><S><I><V><H><E><L><L><W><F><L><R><G><E><T><N><I><K><Y><L><K><D><N><G><V><S><I><W><D><E><W><A><D><A><N><G><D><L><G><P><V><Y><G><S><Q><W><R><S><W><P><A><R><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q3SQ36 |
C6E4K4 | TRUD_GEOSM | tRNA-uridine isomerase D | unclassified Geobacter | <M><S><I><Y><L><T><A><E><V><P><G><T><G><G><V><I><K><A><T><P><E><D><F><L><V><E><E><I><P><A><Y><L><P><S><G><Q><G><E><H><C><F><A><V><L><E><K><R><G><I><A><T><L><E><A><L><R><R><L><A><K><A><L><G><V><Q><E><R><D><L><G><Y><A><G><M><K><D><A><I><G><I><T><R><Q><T><I><S><I><P><R><V><A><P><E><K><V><L><A><L><E><I><P><G><I><T><V><L><S... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | C6E4K4 |
B0TQA0 | TRUB_SHEHH | tRNA-uridine isomerase | Shewanella | <M><A><R><R><S><R><G><R><F><I><D><G><I><L><L><L><D><K><D><T><G><M><S><S><N><F><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><Q><R><T><D><T><S><D><S><D><G><E><I><V><Q><T><R><E><V><N><F><T><Q><E><Q><L... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | B0TQA0 |
P82959 | TXH21_CYRSC | Huwentoxin-II | Cyriopagopus | <M><K><V><T><L><I><A><I><L><T><C><A><A><V><L><V><L><H><T><T><A><A><E><E><L><E><A><E><S><Q><L><M><E><V><G><M><P><D><T><E><L><A><A><V><D><E><E><R><L><F><E><C><S><F><S><C><E><I><E><K><E><G><D><K><P><C><K><K><K><K><C><K><G><G><W><K><C><K><F><N><M><C><V><K><V> | Lethal neurotoxin that blocks neuromuscular transmission. Acts cooperatively to potentiate the activity of huwentoxin-I. This toxin is active against insects.<BOP> | P82959 |
Q4QML9 | TRUD_HAEI8 | tRNA-uridine isomerase D | Haemophilus | <M><L><E><Q><L><P><Y><L><A><L><K><T><P><P><K><T><T><A><L><L><K><A><E><C><A><D><F><I><V><K><E><H><L><G><Y><E><M><S><G><D><G><E><F><V><A><L><Y><V><R><K><T><D><C><N><T><L><F><V><G><E><K><L><A><K><F><A><G><V><S><E><R><N><M><G><Y><A><G><L><K><D><R><R><A><V><T><E><Q><W><F><C><L><Q><M><P><G><M><E><T><P><D><F><S><Q><F><E><L><D... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | Q4QML9 |
B3R8A8 | ZAPD_CUPTR | Z ring-associated protein D | Cupriavidus | <M><I><L><Y><E><Y><P><F><N><E><R><I><R><T><L><L><R><L><E><D><L><F><D><R><L><E><Y><F><L><G><Q><D><H><A><Q><Q><H><H><V><A><L><T><T><L><F><E><I><I><D><V><A><G><R><A><D><L><K><T><D><L><I><K><E><L><E><R><Q><R><Q><A><L><A><P><L><R><A><N><P><Q><I><D><Q><D><A><L><D><S><V><I><G><E><I><E><Q><G><I><A><M><L><N><Q><T><V><G><K><A><G... | Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.<BOP> | B3R8A8 |
Q9K6X9 | UVRB_HALH5 | Excinuclease ABC subunit B | Halalkalibacterium (ex Joshi et al. 2022) | <M><S><Q><S><F><E><L><V><S><Q><Y><K><P><Q><G><D><Q><P><N><A><I><R><Q><L><V><A><G><I><N><E><G><K><K><H><Q><T><L><L><G><A><T><G><T><G><K><T><F><T><M><S><N><V><I><Q><Q><V><N><K><P><T><L><V><I><A><H><N><K><T><L><A><G><Q><L><Y><S><E><F><K><E><F><F><P><N><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><Q><S><D><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q9K6X9 |
Q41738 | THI41_MAIZE | Thiazole biosynthetic enzyme 1 | Zea | <M><A><T><A><A><A><S><S><L><L><K><S><S><F><A><G><S><R><L><P><A><A><T><R><T><T><P><A><S><L><V><V><A><T><G><P><R><G><A><G><A><G><P><I><C><A><S><M><S><M><S><S><S><N><P><P><Y><D><L><T><S><F><R><F><S><P><I><K><E><S><I><V><S><R><E><M><T><R><R><Y><M><T><D><M><I><T><Y><A><D><T><D><V><V><I><V><G><A><G><S><A><G><L><S><C><A><Y><E... | Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue o... | Q41738 |
O94266 | THI22_SCHPO | Hydroxymethylpyrimidine phosphate kinase 2 | Schizosaccharomyces | <M><P><Y><N><P><L><Y><E><S><L><S><N><Q><F><D><P><S><R><I><E><T><V><L><D><P><M><G><Y><T><I><K><R><R><A><L><P><V><S><L><T><I><A><G><S><D><C><S><G><G><A><G><I><Q><A><D><L><K><T><M><T><S><L><G><V><Y><G><M><S><A><I><T><C><L><V><A><E><N><A><G><G><V><D><S><V><E><E><M><S><P><A><F><V><E><S><Q><I><D><C><C><I><R><D><I><P><C><H><V... | Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.<BOP> | O94266 |
A7ZNQ8 | YEGS_ECO24 | Probable lipid kinase YegS | Escherichia | <M><A><E><F><P><A><S><L><L><I><L><N><G><K><S><T><D><N><L><P><L><R><E><A><I><M><L><L><R><E><E><G><M><T><I><H><V><R><V><T><W><E><K><G><D><A><A><R><Y><V><E><E><A><R><K><L><G><V><A><T><V><I><A><G><G><G><D><G><T><I><N><E><V><S><T><A><L><I><Q><C><A><G><D><D><I><P><A><L><G><I><L><P><L><G><T><A><N><D><F><A><T><S><V><G><I><P><E... | Probably phosphorylates lipids; the in vivo substrate is unknown.<BOP> | A7ZNQ8 |
P29501 | TBB2_PEA | Beta-2-tubulin | Pisum | <E><I><V><H><I><Q><G><G><Q><C><G><N><Q><I><G><A><K><F><W><E><V><V><C><A><E><H><G><I><D><P><T><G><R><Y><G><G><D><T><D><L><Q><L><E><R><I><N><V><Y><Y><N><E><A><S><C><G><R><Y><V><P><R><A><V><L><M><D><L><E><P><G><T><M><D><S><V><R><S><G><P><Y><G><Q><I><F><R><P><D><N><F><V><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T><E><G... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | P29501 |
Q9I163 | Y2418_PSEAE | Pirin-like protein PA2418 | Pseudomonas | <M><K><K><V><L><G><I><Y><G><N><A><N><R><H><W><V><G><D><G><F><P><V><R><S><L><F><S><Y><N><T><L><G><Q><H><I><S><P><F><L><L><L><D><Y><A><G><P><A><D><F><P><P><A><Q><Q><R><R><G><V><G><Q><H><P><H><R><G><F><E><T><V><T><I><V><Y><Q><G><E><V><E><H><H><D><S><T><G><A><G><G><R><I><G><P><G><D><V><Q><W><M><T><A><A><S><G><I><L><H><E><E... | Putative quercetin 2,3-dioxygenase.<BOP> | Q9I163 |
Q2TA17 | ZN668_BOVIN | Zinc finger protein 668 | Bos | <M><E><V><E><S><P><E><E><R><S><P><A><P><G><Y><K><R><S><G><R><R><Y><K><C><L><S><C><T><K><T><F><P><N><A><P><R><A><A><R><H><A><A><T><H><G><L><A><D><C><T><E><E><M><A><E><A><K><L><K><P><E><T><D><P><K><A><E><D><A><S><G><D><K><V><S><G><A><A><A><K><P><R><P><Y><A><C><P><L><C><P><K><A><Y><K><T><A><P><E><L><R><S><H><G><R><S><H><T... | May be involved in transcriptional regulation.<BOP> | Q2TA17 |
B8I0U9 | TRPD_RUMCH | Anthranilate phosphoribosyltransferase | Ruminiclostridium | <M><I><Q><E><A><I><Y><Q><V><I><N><K><Q><D><L><D><L><D><K><T><I><Q><V><M><E><E><I><M><E><G><R><A><T><N><A><Q><I><G><S><F><L><T><A><M><R><M><K><G><E><T><I><D><E><I><T><A><C><A><T><V><M><R><Q><K><C><K><R><I><H><P><E><K><D><V><L><D><I><V><G><T><G><G><D><E><A><N><T><F><N><I><S><T><V><S><S><F><V><V><S><A><G><G><V><P><V><A><K... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | B8I0U9 |
Q91053 | VSP1_GLOUS | Snake venom serine protease | Gloydius | <M><V><L><I><S><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><S><S><E><L><V><I><G><G><D><E><C><N><I><N><E><H><R><F><L><V><A><L><Y><N><S><R><S><R><T><L><F><C><G><G><T><L><I><N><Q><E><W><V><L><T><A><A><H><C><E><R><K><N><F><R><I><K><L><G><I><H><S><K><K><V><P><N><E><D><E><Q><T><R><V><P><K><E><K><F><F><C><L><S><S><K><N><Y><T... | Thrombin-like snake venom serine protease. Has a coagulant activity. Acts on alpha-chains of fibrinogen (FGA) generating fibrinopeptide A.<BOP> | Q91053 |
Q4FUL2 | TRPA_PSYA2 | Tryptophan synthase alpha chain | Psychrobacter | <M><T><R><I><E><S><T><F><E><I><L><K><A><Q><N><K><K><A><L><I><P><Y><V><M><A><G><D><P><N><P><S><N><F><V><G><L><L><H><D><L><V><K><H><G><A><D><M><I><E><V><G><L><P><F><S><D><P><M><A><D><G><P><T><V><A><L><A><G><E><R><A><L><A><A><G><T><S><T><R><D><A><L><K><M><V><A><E><F><R><Q><Q><D><T><Q><T><P><I><I><L><M><G><Y><L><N><P><V><E... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q4FUL2 |
P18732 | ZG64_XENLA | Gastrula zinc finger protein XlCGF64.1 | Xenopus | <P><S><G><K><Q><Y><E><C><P><E><C><G><K><T><F><K><Y><K><N><S><L><T><I><H><Q><R><G><H><T><E><E><K><P><F><M><C><T><Q><C><G><K><C><F><R><Q><K><K><A><L><R><R><H><Q><F><I><H><T><G><E><K><P><Y><V><C><T><E><C><E><K><R><F><L><E><K><S><Q><L><I><L><H><Q><R><G><H><T><G><E><K><P><F><T><C><T><E><C><G><E><S><F><R><H><K><Q><V><L><M><R... | May be involved in transcriptional regulation.<BOP> | P18732 |
Q0S3C4 | TSAD_RHOJR | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Rhodococcus | <M><I><V><M><G><I><E><S><S><C><D><E><T><G><V><G><I><V><R><W><N><G><D><G><T><C><E><L><L><A><D><E><V><A><S><S><V><E><E><H><A><R><Y><G><G><V><V><P><E><V><A><S><R><A><H><L><E><A><I><V><P><T><M><R><R><A><L><A><V><A><G><I><A><K><P><D><A><L><A><V><T><I><G><P><G><L><A><G><A><L><L><V><G><V><A><A><A><K><A><Y><A><A><A><W><D><V><P... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q0S3C4 |
P09123 | THRC_BACSL | Threonine synthase | Bacillus | <M><Y><K><G><L><L><K><Q><Y><A><S><Y><L><P><V><N><E><K><T><P><D><V><S><L><M><E><G><N><T><P><L><I><P><L><L><N><I><S><K><Q><L><G><V><Q><L><Y><G><K><Y><E><G><A><N><P><T><G><S><F><K><D><R><G><M><V><M><A><V><A><K><A><K><E><E><G><S><E><A><I><I><C><A><S><T><G><N><T><S><A><S><A><A><A><Y><A><A><R><L><G><M><K><C><I><I><V><I><P><E... | Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP> | P09123 |
P70904 | VLP23_BORHE | Variable large protein 23 | Borrelia | <M><R><K><R><I><S><A><I><I><M><T><L><F><M><V><L><V><S><C><N><S><G><G><V><A><E><D><P><K><T><V><Y><L><T><S><I><A><N><L><G><K><G><F><L><D><V><F><V><T><F><G><D><M><V><A><G><A><F><G><I><K><A><D><T><K><K><S><D><I><G><K><Y><F><N><D><I><E><K><T><M><T><T><V><K><K><R><L><Q><D><E><V><A><K><N><G><N><Y><V><K><V><K><E><V><V><D><K><F... | The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.<BOP> | P70904 |
O48559 | UNI_PEA | Protein UNIFOLIATA | Pisum | <M><D><P><D><A><F><T><A><S><L><F><K><W><D><P><R><T><V><L><S><T><A><P><S><P><R><P><Q><L><L><D><Y><A><V><T><P><T><T><A><P><M><T><Y><H><P><A><R><L><P><R><E><L><G><G><L><E><E><L><F><Q><A><Y><G><I><R><Y><Y><T><A><A><K><I><A><E><L><G><F><T><V><S><T><L><V><D><M><K><D><D><E><L><D><D><M><M><N><S><L><S><Q><I><F><R><W><D><L><L><V... | May regulate indeterminacy during leaf and flower development.<BOP> | O48559 |
Q148G8 | UQCC3_BOVIN | Ubiquinol-cytochrome-c reductase complex assembly factor 3 | Bos | <M><T><T><L><R><K><L><L><L><V><G><A><L><L><G><A><G><A><G><V><G><T><A><L><F><A><L><V><T><P><G><E><E><R><K><Q><A><M><L><K><E><M><P><E><Q><Y><P><Q><R><R><D><E><A><A><R><T><K><E><L><L><L><A><T><L><Q><E><A><A><A><T><Q><E><N><V><A><W><R><K><N><W><M><S><G><G><G><G><G><G><G><G><G><G><R><S><A> | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding pr... | Q148G8 |
Q9FL26 | WRKY8_ARATH | WRKY DNA-binding protein 8 | Arabidopsis | <M><S><H><E><I><K><D><L><N><N><Y><H><Y><T><S><S><Y><N><H><Y><N><I><N><N><Q><N><M><I><N><L><P><Y><V><S><G><P><S><A><Y><N><A><N><M><I><S><S><S><Q><V><G><F><D><L><P><S><K><N><L><S><P><Q><G><A><F><E><L><G><F><E><L><S><P><S><S><S><D><F><F><N><P><S><L><D><Q><E><N><G><L><Y><N><A><Y><N><Y><N><S><S><Q><K><S><H><E><V><V><G><D><G... | Transcription factor. Interacts specifically with the W box (5'-TTGAC[CT]-3'), a frequently occurring stress-responsive cis-acting element. Functions as positive regulator of salt stress response. Binds the W box of LTI78/RD29A stress-response gene and directly regulates its transcription under salt stress. Functions a... | Q9FL26 |
Q8NHX9 | TPC2_HUMAN | Two pore calcium channel protein 2 | Homo | <M><A><E><P><Q><A><E><S><E><P><L><L><G><G><A><R><G><G><G><G><D><W><P><A><G><L><T><T><Y><R><S><I><Q><V><G><P><G><A><A><A><R><W><D><L><C><I><D><Q><A><V><V><F><I><E><D><A><I><Q><Y><R><S><I><N><H><R><V><D><A><S><S><M><W><L><Y><R><R><Y><Y><S><N><V><C><Q><R><T><L><S><F><T><I><F><L><I><L><F><L><A><F><I><E><T><P><S><S><L><T><S... | (Microbial infection) Required for cell entry of coronaviruses SARS-CoV and SARS-CoV-2, as well as human coronavirus EMC (HCoV-EMC), by endocytosis.<BOP> | Q8NHX9 |
P25295 | TBG_SCHPO | Gamma-tubulin | Schizosaccharomyces | <M><G><R><E><I><I><T><L><Q><A><G><Q><C><G><N><Q><I><G><S><Q><F><W><Q><Q><L><C><L><E><H><G><I><G><P><D><G><T><L><E><S><F><A><T><E><G><V><D><R><K><D><V><F><F><Y><Q><S><D><D><T><R><Y><I><P><R><A><I><L><I><D><L><E><P><R><V><V><N><N><I><L><S><D><T><Y><G><S><L><Y><N><P><E><N><I><L><I><T><K><N><G><G><G><A><G><N><N><W><A><N><G... | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.<BOP> | P25295 |
Q8U1G7 | UPP_PYRFU | UPRTase | Pyrococcus | <M><I><E><D><K><R><W><G><G><V><Y><S><F><E><D><S><P><Y><I><M><E><I><L><T><E><L><R><D><K><D><T><D><S><I><K><F><R><K><G><L><V><K><L><G><R><Y><M><G><Y><E><I><T><K><T><M><D><V><E><K><V><K><V><E><T><P><L><E><E><T><E><G><I><I><V><K><D><R><R><N><V><V><I><I><T><V><L><R><A><A><I><P><F><M><E><G><L><I><K><V><F><E><H><A><R><V><G><I... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | Q8U1G7 |
Q5R7Z3 | TRAM1_PONAB | Translocating chain-associated membrane protein 1 | Pongo | <M><A><I><R><K><K><S><T><K><S><P><P><V><L><S><H><E><F><V><L><Q><N><H><A><D><I><V><S><C><V><A><M><V><F><L><L><G><L><M><F><E><I><T><A><K><A><S><I><I><F><V><T><L><Q><Y><N><V><T><L><P><A><T><E><E><Q><A><T><E><S><A><S><L><Y><Y><Y><G><I><K><D><L><A><T><V><F><F><Y><M><L><V><A><I><I><I><H><A><V><I><Q><E><Y><M><L><D><K><I><N><R... | Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilaye... | Q5R7Z3 |
O32036 | TRMR_BACSU | ho5U methyltransferase | Bacillus | <M><T><D><R><Y><E><Q><I><N><D><Y><I><E><A><L><L><K><P><R><P><D><N><V><K><R><L><E><A><Y><A><E><E><H><H><V><P><I><M><E><K><A><G><M><E><V><L><L><Q><I><L><S><V><K><Q><P><K><K><I><L><E><I><G><T><A><I><G><Y><S><A><I><R><M><A><L><E><L><P><S><A><E><I><Y><T><I><E><R><N><E><K><R><H><E><E><A><V><N><N><I><K><E><F><Q><L><D><D><R><I... | Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.<BOP> | O32036 |
Q86ZP5 | TBB_UNCNE | Beta-tubulin | Erysiphe | <M><R><E><I><V><H><L><Q><T><G><Q><C><G><N><Q><I><G><A><A><F><W><Q><T><I><S><G><E><H><G><L><D><G><S><G><V><Y><N><G><T><S><D><L><Q><L><E><R><T><N><V><Y><F><N><E><A><S><G><N><K><Y><V><P><R><A><V><L><V><D><L><E><P><G><T><M><D><A><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><V><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | Q86ZP5 |
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