accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P31831 | TACY_LISIV | Thiol-activated cytolysin | Listeria | <M><K><K><I><M><L><L><L><M><T><L><L><L><V><S><L><P><L><A><Q><E><A><Q><A><D><A><S><V><Y><S><Y><Q><G><I><I><S><H><M><A><P><P><A><S><P><P><A><K><P><K><T><P><V><E><K><K><N><A><A><Q><I><D><Q><Y><I><Q><G><L><D><Y><D><K><N><N><I><L><V><Y><D><G><E><A><V><K><N><V><P><P><K><A><G><Y><K><E><G><N><Q><Y><I><V><V><E><K><K><K><K><S><I... | A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for bind... | P31831 |
Q66I85 | YJU2B_DANRE | Coiled-coil domain-containing protein 130 | Danio | <M><G><E><R><K><G><V><N><K><W><Y><P><P><D><F><D><P><A><K><H><G><S><I><N><G><Y><Y><K><T><H><P><L><R><E><R><A><R><K><L><S><Q><G><I><L><I><I><R><F><E><M><P><Y><N><I><W><C><D><G><C><K><N><H><I><G><M><G><V><R><Y><N><A><E><K><K><K><V><G><N><Y><Y><T><T><P><I><Y><R><F><R><M><K><C><H><L><C><V><N><Y><I><E><M><Q><T><D><P><A><T><C... | May be involved in mRNA splicing.<BOP> | Q66I85 |
P59427 | TYSY_BUCBP | Thymidylate synthase | Buchnera | <M><K><S><Y><L><V><L><L><K><K><I><L><K><E><G><S><N><R><K><D><R><T><G><I><G><T><L><S><V><F><G><Y><H><M><E><F><N><L><K><L><G><F><P><L><I><T><T><K><K><C><H><F><P><A><I><V><H><E><L><L><W><F><L><K><G><D><T><N><I><K><Y><L><N><D><H><N><I><S><I><W><N><P><W><A><D><E><R><G><Y><L><G><P><I><Y><G><E><Q><W><R><S><W><K><T><K><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | P59427 |
Q2YX99 | TMCAL_STAAB | tRNA(Met) cytidine acetate ligase | Staphylococcus | <M><K><S><V><G><L><I><T><E><Y><N><P><F><H><N><G><H><Q><Y><H><I><N><Q><S><K><K><L><T><N><A><D><V><T><I><A><I><M><S><G><N><F><V><M><R><G><E><P><A><I><Y><N><K><F><T><R><A><K><M><A><L><S><T><A><D><L><V><I><E><L><P><A><T><A><S><L><S><S><G><D><H><F><A><E><L><A><V><K><V><A><D><Y><M><S><V><D><T><I><A><F><G><S><E><N><N><D><I><K... | Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.<BOP> | Q2YX99 |
Q4R963 | TCPG_MACFA | CCT-gamma | Macaca | <M><M><G><H><R><P><V><L><V><L><S><Q><N><T><K><R><E><S><G><R><K><V><Q><S><G><N><I><N><A><A><K><T><I><A><D><I><I><R><T><C><L><G><P><K><S><M><M><K><M><L><L><D><P><M><G><G><I><V><M><T><N><D><G><N><A><I><L><R><E><I><Q><V><Q><H><P><A><A><K><S><M><I><E><I><S><R><T><Q><D><E><E><V><G><G><G><T><T><S><V><I><I><L><A><G><E><M><L><S... | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a comple... | Q4R963 |
Q886N9 | UPPS_PSESM | Undecaprenyl pyrophosphate synthase | Pseudomonas | <M><E><K><I><K><S><A><G><P><S><S><V><P><R><H><V><A><I><I><M><D><G><N><N><R><W><A><R><K><R><L><L><P><G><V><A><G><H><K><A><G><V><D><A><V><R><A><V><I><E><V><C><A><E><A><K><V><E><V><L><T><L><F><A><F><S><S><E><N><W><Q><R><P><A><E><E><V><G><A><L><M><E><L><F><F><T><A><L><R><R><E><T><K><R><L><N><E><N><D><I><S><L><R><I><I><G><D... | Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide c... | Q886N9 |
Q9XFG3 | TBG_PHYPA | Gamma-tubulin | Physcomitrium | <M><P><R><E><I><I><T><L><Q><V><G><Q><C><G><N><Q><I><G><M><E><F><W><K><Q><L><C><L><E><H><G><I><S><K><D><G><I><L><E><D><F><A><T><Q><G><G><D><R><K><D><V><F><F><Y><Q><A><D><D><E><H><Y><I><P><R><A><L><L><I><D><L><E><P><R><V><I><N><S><I><Q><N><S><E><Y><R><N><L><Y><N><H><E><N><V><F><V><A><D><H><G><G><G><A><G><N><N><W><A><S><G... | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.<BOP> | Q9XFG3 |
Q5JDJ1 | TRPB2_THEKO | Tryptophan synthase beta chain 2 | Thermococcus | <M><K><A><V><L><P><D><S><K><I><P><K><R><W><Y><N><I><L><P><D><L><P><E><P><L><A><P><P><L><D><P><E><T><D><E><P><M><E><P><E><K><L><L><R><I><F><A><E><E><L><V><K><Q><E><M><S><T><D><R><Y><I><E><I><P><K><E><V><R><E><I><Y><S><K><I><G><R><P><T><P><L><F><R><A><T><N><L><E><R><A><L><G><T><P><A><R><I><Y><F><K><Y><E><G><A><T><V><T><G... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q5JDJ1 |
E1QU22 | TSR3_VULDI | 20S S rRNA accumulation protein 3 homolog | Vulcanisaeta | <M><I><P><R><V><F><I><Y><R><L><P><Q><D><D><P><R><K><N><T><A><I><K><L><V><R><F><G><F><A><Q><L><V><D><S><I><K><A><L><P><S><G><S><I><I><L><D><P><T><V><K><T><P><L><T><P><S><D><R><V><I><A><E><S><R><G><L><S><L><I><D><C><S><W><K><R><A><V><D><V><H><T><K><F><I><R><G><K><F><I><R><R><R><L><P><L><L><I><A><A><N><P><T><H><Y><G><K><P... | Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).<BOP> | E1QU22 |
Q00835 | TRI5_FUSPO | Sesquiterpene cyclase | Fusarium | <M><E><N><F><P><T><E><Y><F><L><N><T><S><V><R><L><L><E><Y><I><R><Y><R><D><S><N><Y><T><R><E><E><R><I><E><N><L><H><Y><A><Y><N><K><A><A><H><H><F><A><Q><P><R><Q><Q><Q><L><L><K><V><D><P><K><R><L><Q><A><S><L><Q><T><I><V><G><M><V><V><Y><S><W><A><K><V><S><K><E><C><M><A><D><L><S><I><H><Y><T><Y><T><L><V><L><D><D><S><S><D><D><P><Y... | TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP> | Q00835 |
B9M7R9 | YIDC_GEODF | Membrane protein YidC | Geotalea | <M><E><K><R><V><V><I><A><V><I><L><S><I><V><V><L><Y><A><F><S><Y><M><F><P><P><P><V><A><N><Q><K><E><K><A><G><P><V><A><A><V><Q><S><Q><P><S><S><A><K><L><S><A><I><D><S><V><P><A><A><A><T><P><Q><A><G><L><A><A><R><N><I><V><V><D><T><D><L><F><I><A><V><F><S><T><K><G><G><G><L><Q><S><F><Q><L><K><H><Y><K><D><K><A><G><A><V><G><R><D><I... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | B9M7R9 |
Q0WQK2 | ZDHC9_ARATH | Zinc finger DHHC domain-containing protein At3g26935 | Arabidopsis | <M><Y><V><V><P><P><P><Q><R><S><D><S><G><S><N><G><D><L><R><V><Y><Q><T><W><K><G><S><N><I><F><F><L><Q><G><R><F><V><F><G><P><D><V><R><S><L><A><L><T><I><C><L><I><A><V><P><V><T><I><F><C><I><F><V><A><R><K><L><I><D><D><F><S><D><S><W><G><V><S><I><V><A><V><A><V><V><F><T><I><Y><D><L><I><L><L><L><L><T><S><G><R><D><P><G><I><I><P><R... | Palmitoyl acyltransferase.<BOP> | Q0WQK2 |
Q39IR6 | UBID_BURL3 | Polyprenyl p-hydroxybenzoate decarboxylase | Burkholderia cepacia complex | <M><K><Y><K><D><L><R><D><F><I><Q><R><L><E><A><L><G><E><L><R><R><V><T><Q><P><V><S><P><V><L><E><M><T><E><L><C><D><R><V><L><R><A><G><G><P><A><L><L><F><N><A><P><T><G><Y><D><F><P><V><L><G><N><L><F><G><T><P><R><R><V><A><L><G><M><G><V><D><A><G><D><D><A><A><L><D><S><L><R><D><L><G><R><L><L><S><A><L><K><E><P><D><P><P><K><S><L><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q39IR6 |
Q8KGF8 | TAL_CHLTE | Probable transaldolase | Chlorobaculum | <M><K><F><F><I><D><T><A><S><L><D><E><I><K><A><A><N><E><L><G><V><L><D><G><V><T><T><N><P><S><L><I><A><K><I><V><K><D><S><T><N><F><T><Y><A><D><F><K><A><H><I><A><K><I><C><E><I><V><D><G><P><V><S><A><E><V><T><T><L><K><A><G><E><M><I><A><Q><G><E><E><L><A><A><I><H><K><N><I><V><V><K><C><P><L><T><V><D><G><L><K><A><I><K><H><F><S><S... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q8KGF8 |
Q0A5V9 | UBIA_ALKEH | 4-HB polyprenyltransferase | Alkalilimnicola | <M><E><M><T><A><D><Y><L><R><D><R><A><W><Q><Y><A><Q><L><T><R><L><N><R><P><I><G><N><F><L><L><L><W><P><M><L><W><G><L><W><I><A><A><K><G><L><P><D><L><K><V><L><V><V><F><V><L><G><V><L><I><M><R><A><A><G><C><V><I><N><D><Y><A><D><R><D><F><D><G><H><V><K><R><T><T><H><R><P><M><A><N><G><R><V><S><E><R><E><A><L><T><L><F><V><V><L><C><L... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | Q0A5V9 |
B4U3P4 | UVRB_STREM | Excinuclease ABC subunit B | Streptococcus | <M><I><D><K><R><D><F><K><A><F><K><L><V><S><K><Y><A><P><S><G><D><Q><P><Q><A><I><E><A><L><V><D><N><I><E><S><G><E><K><A><Q><I><L><L><G><A><T><G><T><G><K><T><Y><T><M><S><Q><V><I><S><K><V><N><K><P><T><L><V><I><A><H><N><K><T><L><A><G><Q><L><Y><G><E><F><K><E><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | B4U3P4 |
A1BEF7 | THIG_CHLPD | Thiazole synthase | Chlorobium | <M><D><F><L><H><L><G><S><F><V><F><S><S><R><L><I><L><G><T><G><K><F><S><N><A><D><L><M><I><E><A><I><K><A><S><G><A><Q><L><V><T><V><A><L><R><R><F><N><R><E><Q><I><A><D><D><L><F><G><P><L><S><A><L><Q><G><I><T><L><M><P><N><T><S><G><A><S><T><A><R><E><A><I><H><A><A><H><I><A><R><E><L><S><G><S><P><F><I><K><V><E><I><H><P><N><P><Q><H... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | A1BEF7 |
Q03774 | TRM82_YEAST | Transfer RNA methyltransferase 82 | Saccharomyces | <M><S><V><I><H><P><L><Q><N><L><L><T><S><R><D><G><S><L><V><F><A><I><I><K><N><C><I><L><S><F><K><Y><Q><S><P><N><H><W><E><F><A><G><K><W><S><D><D><F><D><K><I><Q><E><S><R><N><T><T><A><K><E><Q><Q><G><Q><S><S><E><N><E><N><E><N><K><K><L><K><S><N><K><G><D><S><I><K><R><T><A><A><K><V><P><S><P><G><L><G><A><P><P><I><Y><S><Y><I><R><N... | Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<BOP> | Q03774 |
A1RV13 | UPP_PYRIL | UPRTase | Pyrobaculum | <M><P><V><K><I><I><D><H><V><Y><A><Q><Y><L><L><T><Q><L><R><N><R><N><T><K><G><I><D><F><R><K><G><L><V><R><L><G><R><I><V><G><Y><E><L><V><R><Y><F><P><T><R><E><V><E><V><E><T><P><L><G><K><A><V><G><I><E><I><L><G><L><D><K><V><I><I><V><Q><I><L><R><A><A><M><P><F><V><E><G><L><L><K><A><F><P><Q><A><R><L><G><V><I><A><A><R><R><K><E><E... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | A1RV13 |
P37610 | TAUD_ECOLI | Sulfate starvation-induced protein 3 | Escherichia | <M><S><E><R><L><S><I><T><P><L><G><P><Y><I><G><A><Q><I><S><G><A><D><L><T><R><P><L><S><D><N><Q><F><E><Q><L><Y><H><A><V><L><R><H><Q><V><V><F><L><R><D><Q><A><I><T><P><Q><Q><Q><R><A><L><A><Q><R><F><G><E><L><H><I><H><P><V><Y><P><H><A><E><G><V><D><E><I><I><V><L><D><T><H><N><D><N><P><P><D><N><D><N><W><H><T><D><V><T><F><I><E><T... | Catalyzes the alpha-ketoglutarate-dependent hydroxylation of taurine yielding sulfite and aminoacetaldehyde after decomposition of an unstable intermediate . Is required for the utilization of taurine (2-aminoethanesulfonate) as an alternative sulfur source for growth in the absence of sulfate . To a lesser extent, pen... | P37610 |
B2RXF5 | ZBT42_HUMAN | Zinc finger and BTB domain-containing protein 42 | Homo | <M><E><F><P><E><H><G><G><R><L><L><G><R><L><R><Q><Q><R><E><L><G><F><L><C><D><C><T><V><L><V><G><D><A><R><F><P><A><H><R><A><V><L><A><A><C><S><V><Y><F><H><L><F><Y><R><D><R><P><A><G><S><R><D><T><V><R><L><N><G><D><I><V><T><A><P><A><F><G><R><L><L><D><F><M><Y><E><G><R><L><D><L><R><S><L><P><V><E><D><V><L><A><A><A><S><Y><L><H><M... | Transcriptional repressor. Specifically binds DNA and probably acts by recruiting chromatin remodeling multiprotein complexes.<BOP> | B2RXF5 |
Q084N8 | TRPB_SHEFN | Tryptophan synthase beta chain | Shewanella | <M><T><E><L><K><L><N><P><Y><F><G><E><Y><G><G><M><Y><V><P><Q><I><L><V><P><A><L><K><Q><L><E><T><A><F><V><E><A><Q><Q><D><E><S><F><I><A><E><F><T><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><T><R><N><L><S><P><N><P><L><V><K><I><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><K><E><I... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q084N8 |
Q4L882 | TRUA_STAHJ | tRNA-uridine isomerase I | Staphylococcus | <M><R><I><L><V><N><I><S><Y><Q><G><S><Q><F><L><G><F><Q><I><Q><Q><Q><G><R><T><V><Q><Q><Q><F><E><K><I><L><K><R><M><H><R><R><H><V><R><I><H><P><S><S><R><T><D><R><G><V><H><A><Y><E><Q><F><F><H><F><D><T><D><L><N><I><E><P><K><Q><W><K><Y><A><M><N><S><A><L><P><D><D><I><Y><V><K><E><V><Q><Q><V><D><D><H><F><H><C><R><Y><D><C><L><G><K... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q4L882 |
Q2VY69 | ZN284_HUMAN | Zinc finger protein 284 | Homo | <M><T><M><F><K><E><A><V><T><F><K><D><V><A><V><V><F><T><E><E><E><L><G><L><L><D><V><S><Q><R><K><L><Y><R><D><V><M><L><E><N><F><R><N><L><L><S><V><G><H><Q><L><S><H><R><D><T><F><H><F><Q><R><E><E><K><F><W><I><M><E><T><A><T><Q><R><E><G><N><S><G><G><K><I><Q><T><E><L><E><S><V><P><E><T><G><P><H><E><E><W><S><C><Q><Q><I><W><E><Q><T... | May be involved in transcriptional regulation.<BOP> | Q2VY69 |
B4RWG2 | Y3196_ALTMD | Nucleotide-binding protein MADE_1004170 | Alteromonas | <M><K><L><I><I><I><S><G><R><S><G><S><G><K><S><V><A><L><R><A><L><E><D><L><G><Y><Y><C><V><D><N><I><P><V><N><L><L><P><T><L><T><H><T><V><V><D><E><Y><D><Q><V><A><V><S><I><D><V><R><N><L><P><K><N><P><D><D><L><V><E><I><L><D><Y><L><P><S><S><W><S><M><T><I><V><Y><I><D><A><S><D><D><V><L><V><K><R><F><S><E><T><R><R><L><H><P><L><A><K... | Displays ATPase and GTPase activities.<BOP> | B4RWG2 |
B5GW45 | TMUUS_STRCL | Type I terpene synthase | Streptomyces | <M><S><L><N><H><S><D><L><M><F><Y><C><P><V><D><D><L><P><H><P><A><A><S><G><V><N><D><R><T><L><D><W><A><S><G><Q><G><I><P><T><A><D><R><D><A><G><R><L><R><A><M><A><P><G><L><L><A><A><R><I><A><P><D><A><R><G><P><V><L><D><A><F><A><D><H><H><T><W><L><F><A><F><D><D><E><Y><C><D><R><A><D><G><S><G><I><T><E><W><A><S><F><L><A><R><L><H><R... | Catalyzes the conversion of (2E,6E)-farnesyl diphosphate (FPP) into (+)-T-muurolol via a 1,10-cyclization, which requires isomerization of FPP to nerolidyl diphosphate (NPP) and then abstraction of the pyrophosphate from intermediate NPP leading to a (E,Z)-germacradienyl (helminthogermacradienyl) cation.<BOP> | B5GW45 |
B7LJY3 | UVRB_ESCF3 | Excinuclease ABC subunit B | Escherichia | <M><S><K><P><F><K><L><N><S><A><F><K><P><S><G><D><Q><P><E><A><I><R><R><L><E><E><G><L><E><D><G><L><A><H><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><I><A><N><V><I><A><D><L><Q><R><P><T><M><V><L><A><P><N><K><T><L><A><A><Q><L><Y><G><E><M><K><E><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><S><S><D><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | B7LJY3 |
Q8E7Q5 | TRUA_STRA3 | tRNA-uridine isomerase I | Streptococcus | <M><T><R><Y><K><A><Q><I><S><Y><D><G><S><A><F><S><G><F><Q><R><Q><P><N><C><R><T><V><Q><E><E><I><E><R><T><L><K><R><L><N><S><G><N><D><V><I><I><H><G><A><G><R><T><D><A><G><V><H><A><Y><G><Q><V><I><H><F><D><L><P><Q><A><R><D><V><E><K><L><R><F><G><L><D><T><Q><C><P><D><D><I><D><I><V><K><V><E><Q><V><S><D><D><F><H><C><R><Y><D><K><H... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q8E7Q5 |
P77288 | YFCV_ECOLI | Uncharacterized fimbrial-like protein YfcV | Escherichia | <M><S><K><F><V><K><T><A><I><A><A><A><M><V><M><G><A><F><T><S><T><A><T><I><A><A><G><N><N><G><T><A><R><F><Y><G><T><I><E><D><S><V><C><S><I><V><P><D><D><H><K><L><E><V><D><M><G><D><I><G><A><E><K><L><K><N><N><G><T><T><T><P><K><N><F><Q><I><R><L><Q><D><C><V><F><D><T><Q><E><T><M><T><T><T><F><T><G><T><V><S><S><A><N><S><G><N><Y><Y... | Part of the yfcOPQRSUV fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.<BOP> | P77288 |
Q11IP4 | XGPT_CHESB | Xanthine phosphoribosyltransferase | unclassified Chelativorans | <M><S><L><P><E><K><A><F><P><V><S><W><D><Q><F><H><R><D><A><R><A><L><A><W><R><L><A><G><T><N><G><R><W><Q><A><I><V><C><I><T><R><G><G><L><V><P><A><A><V><I><A><R><E><L><G><I><R><L><I><E><T><V><C><I><A><S><Y><H><D><Y><S><E><Q><G><E><L><K><V><L><K><E><I><S><P><S><L><L><E><E><D><G><Q><N><I><L><I><V><D><D><L><T><D><T><G><K><T><A... | Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with... | Q11IP4 |
A7FMH4 | TYPH_YERP3 | TdRPase | Yersinia | <M><F><L><A><Q><E><I><I><R><K><K><R><D><G><Q><P><L><S><E><E><E><I><R><F><F><I><N><G><I><R><D><N><V><V><S><E><G><Q><I><A><A><L><A><M><T><I><Y><F><H><D><M><S><M><P><E><R><V><A><L><T><M><A><M><R><D><S><G><T><V><L><N><W><K><S><L><N><L><N><G><P><L><V><D><K><H><S><T><G><G><V><G><D><V><T><S><L><M><L><G><P><M><V><A><A><C><G><G... | The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP> | A7FMH4 |
P44560 | TATC_HAEIN | Sec-independent protein translocase protein TatC | Haemophilus | <M><S><N><V><D><E><S><Q><P><L><I><T><H><L><V><E><L><R><N><R><L><L><R><C><V><I><C><V><V><L><V><F><V><A><L><V><Y><F><S><N><D><I><Y><H><F><V><A><A><P><L><T><A><V><M><P><K><G><A><T><M><I><A><T><N><I><Q><T><P><F><F><T><P><I><K><L><T><A><I><V><A><I><F><I><S><V><P><Y><L><L><Y><Q><I><W><A><F><I><A><P><A><L><Y><Q><H><E><K><R><M... | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP> | P44560 |
O82827 | UPPS_MICLU | Undecaprenyl pyrophosphate synthase | Micrococcus | <M><F><P><I><K><K><R><K><A><I><K><N><N><N><I><N><A><A><Q><I><P><K><H><I><A><I><I><M><D><G><N><G><R><W><A><K><Q><K><K><M><P><R><I><K><G><H><Y><E><G><M><Q><T><V><K><K><I><T><R><Y><A><S><D><L><G><V><K><Y><L><T><L><Y><A><F><S><T><E><N><W><S><R><P><K><D><E><V><N><Y><L><M><K><L><P><G><D><F><L><N><T><F><L><P><E><L><I><E><K><N... | Generates ditrans,octacis-undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP) and farnesyl diphosphate. UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.<BOP> | O82827 |
P48970 | UNIV_STRPU | Univin | Strongylocentrotus | <M><D><V><S><K><V><L><I><L><T><L><I><W><L><L><T><A><D><S><A><P><P><D><Y><V><T><L><T><R><K><M><E><S><K><I><L><R><V><M><G><L><S><E><R><P><R><P><K><P><N><A><T><A><P><Q><Y><M><W><D><L><Y><R><Q><Q><M><A><A><T><E><G><A><A><A><S><R><G><G><E><T><E><I><G><K><E><E><E><E><D><G><R><P><C><S><E><T><K><L><S><S><N><I><I><R><S><V><S><H... | Could have a critical role in early developmental decisions in the sea urchin embryo.<BOP> | P48970 |
A4YM32 | UREF_BRASO | Urease accessory protein UreF | unclassified Bradyrhizobium | <M><T><T><N><D><A><G><R><I><P><S><A><A><G><G><A><E><L><A><A><L><Y><R><L><L><T><W><L><S><P><A><F><P><I><G><G><F><S><Y><S><S><G><L><E><W><A><V><E><A><G><D><I><C><D><A><A><A><L><R><G><W><L><A><T><M><L><T><D><G><S><G><F><C><D><A><A><F><L><V><H><A><H><R><A><T><E><L><D><D><I><K><R><L><S><E><V><A><E><L><A><A><A><F><V><P><S><R... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | A4YM32 |
B6H3B2 | VEA_PENRW | Velvet complex subunit A | Penicillium chrysogenum species complex | <M><A><N><R><P><S><L><M><P><P><H><N><E><T><E><H><S><V><S><R><I><T><R><E><G><K><Q><L><T><Y><K><L><S><V><M><Q><Q><P><E><R><A><R><A><C><G><A><G><A><K><S><S><A><D><R><R><P><V><D><P><P><P><V><V><E><L><R><I><F><E><S><D><P><A><N><D><T><Q><K><T><D><I><T><F><A><Y><N><A><N><F><F><L><Y><A><T><L><E><T><A><R><P><I><A><H><G><R><V><G... | Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination . The velvet complex acts as a global regulator for secondary metabolite gene expression . Con... | B6H3B2 |
P62017 | VATD_SULTO | V-ATPase subunit D | Sulfurisphaera | <M><S><S><R><K><I><L><P><T><K><L><N><L><I><N><L><R><K><Q><I><R><L><T><R><T><I><K><R><L><L><E><N><K><R><E><V><L><L><I><Y><L><R><E><Y><A><N><E><Y><E><K><L><Y><S><E><V><S><Q><L><L><K><E><V><Y><E><T><Y><L><M><G><V><S><A><E><G><I><S><T><V><E><S><Y><A><N><S><V><P><P><S><L><Q><V><K><S><D><L><K><V><L><F><G><V><R><I><P><I><V><K... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | P62017 |
B0BSW9 | TORD_ACTPJ | Chaperone protein TorD | Actinobacillus | <M><A><H><S><Q><L><L><S><S><E><E><R><L><F><C><Y><R><W><F><H><S><L><L><A><K><E><L><S><E><P><Q><L><Q><A><L><Q><A><G><Q><F><A><S><F><F><A><F><L><A><E><L><G><F><Q><P><Q><V><T><D><L><Q><N><E><L><A><K><L><T><A><Y><D><S><P><R><L><E><L><A><A><D><F><A><Q><C><F><L><L><E><G><K><L><S><A><L><P><Y><A><S><Y><Y><L><D><E><R><D><L><S><E... | Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP> | B0BSW9 |
P0DPW9 | TX41A_SCODE | Toxin SSD219 | Scolopendra | <M><K><K><T><C><V><V><S><V><F><L><V><L><L><L><L><K><F><H><D><L><S><M><G><E><E><I><S><P><L><K><K><V><A><P><R><E><Q><I><F><P><C><P><G><F><P><C><P><K><G><Y><F><C><D><K><G><S><Q><K><C><R><E><G><T><D> | Voltage-gated potassium channel inhibitor.<BOP> | P0DPW9 |
Q8XAX1 | YDEP_ECO57 | Protein YdeP | Escherichia | <M><K><K><K><I><E><S><Y><Q><G><A><A><G><G><W><G><A><V><K><S><V><A><N><A><V><R><K><Q><M><D><I><R><Q><D><V><I><A><M><F><D><M><N><K><P><E><G><F><D><C><P><G><C><A><W><P><D><P><K><H><S><A><S><F><D><I><C><E><N><G><A><K><A><I><A><W><E><V><T><D><K><Q><V><N><A><S><F><F><A><Q><N><T><V><Q><S><L><L><T><W><G><D><H><E><L><E><A><A><G... | Probably involved in acid resistance.<BOP> | Q8XAX1 |
P63315 | TNNC1_BOVIN | Troponin C, slow skeletal and cardiac muscles | Bos | <M><D><D><I><Y><K><A><A><V><E><Q><L><T><E><E><Q><K><N><E><F><K><A><A><F><D><I><F><V><L><G><A><E><D><G><C><I><S><T><K><E><L><G><K><V><M><R><M><L><G><Q><N><P><T><P><E><E><L><Q><E><M><I><D><E><V><D><E><D><G><S><G><T><V><D><F><D><E><F><L><V><M><M><V><R><C><M><K><D><D><S><K><G><K><S><E><E><E><L><S><D><L><F><R><M><F><D><K><N... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P63315 |
B9VJ80 | UBA5_BOMMO | Ubiquitin-like modifier-activating enzyme 5 | Bombyx | <M><A><S><V><D><E><L><Q><K><K><I><K><E><L><E><A><K><L><A><A><V><E><A><K><G><G><P><M><R><Q><K><I><E><V><M><S><S><E><V><V><D><S><N><P><Y><S><R><L><M><A><L><K><R><M><G><I><V><N><N><Y><E><Q><I><R><E><K><T><V><A><V><V><G><V><G><G><V><G><S><V><T><A><E><M><L><T><R><C><G><I><G><K><L><I><L><F><D><Y><D><K><V><E><L><A><N><M><N><R... | E1-like enzyme which activates UFM1.<BOP> | B9VJ80 |
Q7V2G1 | TAL_PROMP | Transaldolase | Prochlorococcus | <M><K><S><I><L><E><Q><L><S><S><I><T><V><V><V><A><D><T><G><D><L><D><A><I><K><K><F><Q><P><R><D><A><T><T><N><P><S><L><I><L><A><A><A><K><N><P><D><Y><I><K><L><I><D><Q><A><L><E><S><S><R><K><S><L><P><A><G><F><S><E><S><E><L><I><K><E><T><I><D><Q><V><S><V><F><F><G><K><E><I><L><N><L><I><S><G><R><V><S><T><E><V><D><A><R><L><S><F><D... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q7V2G1 |
Q9BSH4 | TACO1_HUMAN | Translational activator of mitochondrially-encoded cytochrome c oxidase I | Homo | <M><S><A><W><A><A><A><S><L><S><R><A><A><A><R><C><L><L><A><R><G><P><G><V><R><A><A><P><P><R><D><P><R><P><S><H><P><E><P><R><G><C><G><A><A><P><G><R><T><L><H><F><T><A><A><V><P><A><G><H><N><K><W><S><K><V><R><H><I><K><G><P><K><D><V><E><R><S><R><I><F><S><K><L><C><L><N><I><R><L><A><V><K><E><G><G><P><N><P><E><H><N><S><N><L><A><N... | Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.<BOP> | Q9BSH4 |
A4IJS3 | UPPP_GEOTN | Undecaprenyl pyrophosphate phosphatase | Geobacillus | <M><D><W><M><E><L><L><K><A><V><I><L><G><M><V><E><G><L><T><E><F><A><P><V><S><S><T><G><H><M><I><I><V><D><D><L><W><L><K><S><T><E><F><L><G><K><Y><A><A><N><T><F><K><V><V><I><Q><L><G><S><I><L><A><A><V><V><V><F><K><D><R><F><L><E><L><L><G><I><R><G><R><H><P><G><G><K><P><R><L><T><L><L><H><V><I><I><G><L><L><P><A><G><V><L><G><V><L... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | A4IJS3 |
Q7X660 | YSL11_ORYSJ | Protein YELLOW STRIPE LIKE 11 | Oryza sativa | <M><A><S><A><A><A><N><N><S><S><S><A><A><Y><D><A><A><E><T><G><G><L><L><R><R><R><N><T><T><A><A><A><R><G><N><A><G><E><E><E><E><E><A><E><A><V><A><P><S><V><E><Q><A><F><A><D><K><P><V><P><S><W><R><E><Q><L><T><V><R><A><F><V><V><G><F><L><L><S><I><M><F><N><I><I><V><M><K><L><S><L><T><T><G><V><I><P><S><L><N><V><S><A><S><L><L><G><F... | May be involved in the transport of nicotianamine-chelated metals.<BOP> | Q7X660 |
A5F7I4 | YCIB_VIBC3 | Inner membrane-spanning protein YciB | Vibrio | <M><K><Q><L><L><D><F><I><P><L><I><I><F><F><A><L><Y><K><F><Y><D><I><Y><V><A><T><G><A><L><I><A><A><T><T><L><Q><V><I><V><T><Y><A><M><Y><K><K><V><E><K><M><Q><L><I><T><F><V><M><V><A><L><F><G><G><M><T><L><A><L><H><D><D><N><F><I><K><W><K><V><T><I><V><Y><V><V><F><A><L><G><L><T><I><S><Q><I><M><G><K><P><A><I><K><G><M><L><G><K><E... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | A5F7I4 |
Q1GR76 | UPPP_SPHAL | Undecaprenyl pyrophosphate phosphatase | Sphingopyxis | <M><H><D><L><A><T><I><I><L><L><G><I><I><E><G><L><T><E><F><L><P><V><S><S><T><G><H><L><I><L><A><S><E><M><L><G><F><T><G><E><G><S><A><A><F><K><I><A><I><Q><L><G><A><I><L><A><V><L><V><A><Y><R><A><R><F><W><G><V><G><M><G><L><L><R><A><D><P><A><A><V><A><F><T><R><N><I><L><I><G><F><L><P><A><M><L><V><G><A><V><A><Y><E><G><V><R><A><L... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q1GR76 |
Q7VRJ3 | UBID_BLOFL | Polyprenyl p-hydroxybenzoate decarboxylase | Candidatus Blochmannia | <M><T><Y><K><D><L><R><N><F><I><K><T><L><E><Y><Q><G><E><L><K><K><I><D><F><P><V><D><P><N><L><E><I><T><E><I><A><H><R><T><L><K><S><Q><G><P><A><L><L><F><T><N><P><I><G><H><S><I><P><I><L><C><N><L><F><G><T><I><S><R><I><E><L><G><I><G><I><K><N><I><L><S><L><R><D><I><G><K><L><L><A><F><L><K><E><P><Q><I><P><T><G><F><R><D><F><L><S><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q7VRJ3 |
A2BTJ3 | THIC_PROMS | Thiamine biosynthesis protein ThiC | Prochlorococcus | <M><R><S><S><W><I><K><P><R><L><G><K><D><N><V><T><Q><M><N><F><A><R><N><G><Y><I><T><E><E><M><D><F><V><A><K><K><E><N><L><P><S><S><L><I><M><E><E><V><A><R><G><R><L><I><I><P><A><N><I><N><H><L><N><L><E><P><M><S><I><G><I><A><S><R><C><K><V><N><A><N><I><G><A><S><P><N><A><S><D><I><N><E><E><V><E><K><L><K><L><A><V><K><Y><G><A><D><T... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A2BTJ3 |
C5BB78 | ZAPB_EDWI9 | Cell division protein ZapB | Edwardsiella | <M><S><F><E><V><F><E><K><L><E><A><K><V><Q><Q><A><I><D><T><I><T><L><L><Q><M><E><I><E><E><L><K><E><K><N><N><Q><L><N><Q><E><V><Q><Q><A><A><S><N><R><E><G><L><L><R><E><N><E><Q><L><K><H><E><Q><E><A><W><Q><E><R><L><R><A><L><L><G><K><M><N><E><V><N> | Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.<BOP... | C5BB78 |
Q2GS33 | VPS27_CHAGB | Vacuolar protein sorting-associated protein 27 | Chaetomium | <M><M><G><W><W><S><S><G><A><N><N><A><L><D><E><Q><I><D><K><A><T><S><S><S><L><E><D><I><A><L><N><L><E><I><S><D><I><I><R><S><K><T><V><Q><P><K><E><A><M><R><S><L><K><K><R><I><N><N><K><N><P><N><T><Q><L><S><A><L><N><L><T><D><T><C><V><K><N><G><G><A><H><F><L><A><E><I><A><S><R><E><F><M><E><S><L><V><S><L><L><K><A><V><G><P><G><T><V... | Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP> | Q2GS33 |
O43280 | TREA_HUMAN | Alpha,alpha-trehalose glucohydrolase | Homo | <M><P><G><R><T><W><E><L><C><L><L><L><L><L><G><L><G><L><G><S><Q><E><A><L><P><P><P><C><E><S><E><I><Y><C><H><G><E><L><L><N><Q><V><Q><M><A><K><L><Y><Q><D><D><K><Q><F><V><D><M><P><L><S><I><A><P><E><Q><V><L><Q><T><F><T><E><L><S><R><D><H><N><H><S><I><P><R><E><Q><L><Q><A><F><V><H><E><H><F><Q><A><K><G><Q><E><L><Q><P><W><T><P><A... | Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.<BOP> | O43280 |
Q5FL49 | TPIS_LACAC | Triose-phosphate isomerase | Lactobacillus | <M><S><R><T><P><I><I><A><G><N><W><K><L><H><M><N><P><E><Q><T><T><E><F><V><D><A><V><K><G><K><L><P><D><P><S><K><V><E><S><L><I><C><A><P><A><V><D><L><D><A><L><R><K><A><A><E><G><S><N><L><H><I><G><A><E><N><C><Y><F><E><D><E><G><A><Y><T><G><E><T><S><P><K><V><L><K><E><M><G><I><D><Y><V><I><I><G><H><S><E><R><R><G><Y><F><H><E><T><D... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q5FL49 |
P33226 | TORC_ECOLI | Cytochrome c-type protein TorC | Escherichia | <M><R><K><L><W><N><A><L><R><R><P><S><A><R><W><S><V><L><A><L><V><A><I><G><I><V><I><G><I><A><L><I><V><L><P><H><V><G><I><K><V><T><S><T><T><E><F><C><V><S><C><H><S><M><Q><P><V><Y><E><E><Y><K><Q><S><V><H><F><Q><N><A><S><G><V><R><A><E><C><H><D><C><H><I><P><P><D><I><P><G><M><V><K><R><K><L><E><A><S><N><D><I><Y><Q><T><F><I><A><H... | Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal domain of TorC, then from the N-terminus to the C-terminus, and fina... | P33226 |
A2T334 | YCF3_ANGEV | Photosystem I assembly protein Ycf3 | Angiopteris | <M><P><R><S><Q><R><N><D><N><F><I><D><K><T><F><T><I><V><A><D><I><L><L><R><V><I><P><T><T><Q><R><E><K><E><A><F><T><Y><Y><R><D><G><M><S><A><Q><S><E><G><E><Y><A><E><A><L><Q><N><Y><Y><K><A><M><R><L><E><I><D><P><Y><D><R><S><Y><I><L><Y><N><I><G><L><I><H><T><S><N><G><E><H><A><K><A><L><E><Y><Y><S><Q><A><L><E><R><N><P><S><L><P><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | A2T334 |
B0TP00 | Y1591_SHEHH | Nucleoid-associated protein Shal_1591 | Shewanella | <M><F><G><K><G><G><M><G><N><L><M><K><Q><A><Q><Q><M><Q><D><K><M><A><K><V><Q><E><E><I><A><R><M><E><V><T><G><E><A><G><A><G><L><V><K><V><T><M><T><G><S><H><S><V><R><K><V><D><I><D><A><S><L><L><E><D><D><K><E><M><L><E><D><L><I><A><A><A><C><N><D><A><A><R><R><V><E><E><N><Q><K><E><K><M><A><E><V><T><G><G><M><Q><L><P><P><G><M><K><M... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | B0TP00 |
Q4QJX4 | UVRB_HAEI8 | Excinuclease ABC subunit B | Haemophilus | <M><S><E><K><I><N><T><K><P><F><I><L><H><S><D><F><R><P><S><G><D><Q><P><Q><A><I><E><K><L><A><E><N><L><T><D><G><L><A><H><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><I><A><N><V><I><A><Q><L><N><R><P><A><M><L><L><A><P><N><K><T><L><A><A><Q><L><Y><A><E><M><K><A><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q4QJX4 |
Q3JEI2 | TYSY_NITOC | Thymidylate synthase | Nitrosococcus | <M><K><P><Y><L><E><L><I><Q><K><I><L><D><T><G><V><E><R><D><D><R><T><G><T><G><T><W><S><I><F><G><H><Q><M><R><F><D><L><R><Q><G><F><P><L><I><T><T><K><K><L><H><I><R><A><I><F><I><E><L><L><W><F><L><R><G><E><T><N><V><K><Y><L><H><D><H><G><V><T><I><W><D><E><W><A><D><E><Q><G><E><L><G><P><I><Y><G><Y><Q><W><R><S><W><P><L><P><D><G><G... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q3JEI2 |
Q43848 | TKTC_SOLTU | Transketolase, chloroplastic | Solanum | <M><A><S><S><S><S><L><T><L><S><Q><V><I><F><S><P><S><L><P><R><H><G><S><S><S><S><S><S><P><S><L><S><F><S><T><F><S><G><L><K><S><T><P><F><T><S><S><H><R><R><I><L><P><S><T><T><V><T><K><Q><Q><F><S><V><R><A><S><A><A><V><E><T><L><E><K><T><D><A><A><I><V><E><K><S><V><N><T><I><R><F><L><A><I><D><A><V><E><K><A><N><S><G><H><P><G><L><P... | Catalyzes the reversible transfer of a two-carbon ketol group from fructose-6-phosphate or sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to yield xylulose-5-phosphate and erythrose-4-phosphate or ribose-5-phosphate, respectively.<BOP> | Q43848 |
B5QYE5 | THIG_SALEP | Thiazole synthase | Salmonella | <M><L><R><I><A><D><K><T><F><D><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><A><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><A><P><L><I><E><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><Q><L><A><R><E><A><L><G><T><N><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | B5QYE5 |
P54078 | TATC_MYCLE | Sec-independent protein translocase protein TatC | Mycobacterium | <M><R><A><C><D><L><L><K><R><I><K><Q><H><Y><R><R><S><R><T><N><P><D><A><T><M><S><L><I><D><H><L><T><E><L><R><T><R><L><L><I><S><L><A><A><I><V><V><T><T><I><F><G><F><I><W><Y><S><H><S><I><F><G><L><E><S><L><G><E><W><L><R><R><P><Y><C><S><L><P><Q><S><A><R><A><D><I><S><P><D><G><Q><C><R><L><L><A><T><A><P><F><D><Q><F><M><L><R><I><K... | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP> | P54078 |
Q9V0K1 | UPP_PYRAB | UPRTase | Pyrococcus | <M><I><E><D><K><R><W><K><G><V><Y><S><F><E><D><S><P><F><I><M><E><I><L><T><Q><L><R><D><K><N><T><D><S><I><E><F><R><K><G><L><V><K><L><G><R><Y><M><G><Y><E><L><T><K><T><M><E><V><E><K><V><K><V><E><T><P><L><E><E><T><E><G><I><I><V><K><D><R><R><N><V><V><I><I><T><V><L><R><A><A><I><P><L><M><E><G><L><I><K><V><F><E><H><A><R><V><G><I... | Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP> | Q9V0K1 |
Q5XAG6 | TRMB_STRP6 | tRNA(m7G46)-methyltransferase | Streptococcus | <M><R><V><R><K><R><K><G><A><E><E><H><L><A><N><N><P><H><Y><V><I><L><N><P><E><D><A><K><G><R><W><H><D><V><F><G><N><D><R><P><I><H><I><E><V><G><S><G><K><G><G><F><I><T><G><M><A><L><K><N><P><D><I><N><Y><I><G><I><D><I><Q><L><S><V><L><S><Y><A><L><D><K><V><L><A><S><E><V><S><N><V><K><L><L><R><V><D><G><S><S><L><T><N><Y><F><E><D><G... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | Q5XAG6 |
Q8FZV9 | UREG2_BRUSU | Urease accessory protein UreG 2 | Brucella | <M><K><K><I><P><R><I><G><V><G><G><P><V><G><S><G><K><M><A><I><I><E><A><V><V><P><I><L><I><K><L><G><Y><R><I><L><V><I><T><N><D><I><V><T><T><E><D><A><K><H><V><Q><R><T><L><K><G><V><L><I><E><D><R><I><V><G><V><E><T><G><G><C><P><H><T><A><V><R><E><D><P><S><M><N><L><A><A><V><E><E><M><E><A><K><F><P><D><T><D><L><V><L><L><E><S><G><G... | Disrupting the ure2 operon has no effect on urease activity, or pathogen survival in BALB/c mice when inoculated by gavage, but confers slightly enhanced resistance to low pH killing in vitro.<BOP> | Q8FZV9 |
Q75WH3 | TX24A_MACGS | Neurotoxin magi-10 | Macrothele | <M><K><V><F><S><F><T><V><V><V><V><M><I><L><S><L><S><A><F><V><L><A><G><D><E><G><D><V><M><K><K><I><V><A><M><E><E><A><V><E><E><R><A><C><L><A><E><Y><Q><K><C><E><G><S><T><V><P><C><C><P><G><L><S><C><S><A><G><R><F><R><K><T><K><L><C><T><K> | Inhibits Kv11.1/KCNH2/ERG1, Kv1.1/KCNA1 and Kv1.3/KCNA3 voltage-gated potassium channels and Nav1.7/SCN9A voltage-gated sodium channels . In vivo, intracranial injection into mice causes lack of coordination for 10 min, followed by fast recovery.<BOP> | Q75WH3 |
P41388 | TBB_VENIN | Beta-tubulin | Venturia | <M><R><E><I><V><H><L><Q><T><G><Q><C><G><N><Q><I><G><A><A><F><W><Q><T><I><S><G><E><H><G><L><D><G><S><G><V><Y><N><G><T><S><D><L><Q><L><E><R><M><N><V><Y><F><N><E><A><S><G><N><K><F><V><P><R><A><V><L><V><D><L><E><P><G><T><M><D><A><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><V><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | P41388 |
A7I162 | THIC_CAMHC | Thiamine biosynthesis protein ThiC | Campylobacter | <M><R><S><Q><W><L><K><N><R><K><N><D><K><T><P><T><Q><M><Y><Y><A><K><N><G><I><I><T><E><E><M><R><Y><V><A><K><I><E><Q><M><D><A><E><I><L><R><S><E><V><A><R><G><K><T><I><I><P><A><N><I><N><H><T><N><L><V><P><M><G><I><G><R><S><L><K><C><K><I><N><S><N><I><G><S><S><S><V><S><S><G><V><E><E><E><V><E><K><L><K><I><S><I><K><Y><G><A><D><T... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A7I162 |
Q328K6 | ULAR_SHIDS | HTH-type transcriptional regulator UlaR | Shigella | <M><T><E><A><Q><R><H><Q><I><L><L><E><M><L><A><Q><L><G><F><V><T><V><E><K><V><V><E><R><L><G><I><S><P><A><T><A><R><R><D><I><N><K><L><D><E><S><G><K><L><K><K><V><R><N><G><A><E><A><I><T><Q><Q><R><P><R><W><T><P><M><N><L><H><Q><A><Q><N><H><D><E><K><V><R><I><A><K><A><A><S><Q><L><V><N><P><G><E><S><V><V><I><N><C><G><S><T><A><F><L... | Represses ulaG and the ulaABCDEF operon.<BOP> | Q328K6 |
C6DJE0 | YIHI_PECCP | Der GTPase-activating protein YihI | Pectobacterium | <M><N><R><P><V><K><G><A><A><D><K><A><G><K><P><K><V><K><R><K><T><R><E><E><L><E><R><E><A><R><E><R><K><K><D><K><K><H><R><G><H><V><A><G><S><R><T><Q><E><K><A><S><T><D><Q><R><S><G><Q><R><K><A><A><D><P><R><I><G><S><K><K><P><V><P><L><G><V><L><D><S><A><V><A><K><P><K><P><K><S><K><P><S><A><P><V><E><N><V><V><A><A><K><P><T><M><S><P... | A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.<BOP> | C6DJE0 |
Q0BTT3 | UPPP_GRABC | Undecaprenyl pyrophosphate phosphatase | Granulibacter | <M><R><I><E><S><M><N><A><I><Q><A><I><A><I><A><I><L><Q><G><A><T><E><L><F><P><V><S><S><L><G><H><A><V><V><L><P><A><L><L><G><W><S><L><P><Q><H><S><Q><T><F><L><P><F><L><V><F><L><H><L><G><T><A><A><A><L><L><L><Y><F><W><R><D><W><W><A><L><F><S><G><V><I><G><F><A><P><A><H><H><V><P><Q><A><R><R><I><F><M><L><L><V><V><A><T><L><P><A><I... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q0BTT3 |
P57970 | UBIA_PASMU | 4-HB polyprenyltransferase | Pasteurella | <M><P><I><S><K><Q><K><W><I><A><Y><A><Q><L><M><R><F><D><K><P><I><G><T><L><L><L><L><W><P><T><L><W><A><L><F><L><S><V><K><G><M><P><D><L><S><I><L><S><I><F><V><L><G><V><I><F><M><R><A><A><G><C><V><I><N><D><Y><A><D><R><H><I><D><G><A><V><K><R><T><S><K><R><P><L><A><T><G><A><A><T><P><E><E><A><K><W><L><F><V><L><L><V><F><C><S><F><I... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | P57970 |
A2BLE8 | TOP6A_HYPBU | Type II DNA topoisomerase VI subunit A | Hyperthermus | <M><A><E><E><Y><V><D><V><V><D><I><E><A><R><K><K><A><L><A><V><F><R><E><K><F><K><E><I><L><E><Q><V><M><R><G><E><N><P><T><I><M><L><P><K><R><T><L><S><N><T><I><Y><D><E><K><R><K><L><L><L><L><G><P><E><K><L><K><R><S><F><F><D><L><H><E><S><K><K><F><M><Q><T><L><L><M><A><R><I><I><Y><E><A><L><E><R><N><E><Y><P><T><I><R><D><L><Y><Y><R... | Relaxes both positive and negative superturns and exhibits a strong decatenase activity.<BOP> | A2BLE8 |
O15273 | TELT_HUMAN | Titin cap protein | Homo | <M><A><T><S><E><L><S><C><E><V><S><E><E><N><C><E><R><R><E><A><F><W><A><E><W><K><D><L><T><L><S><T><R><P><E><E><G><C><S><L><H><E><E><D><T><Q><R><H><E><T><Y><H><Q><Q><G><Q><C><Q><V><L><V><Q><R><S><P><W><L><M><M><R><M><G><I><L><G><R><G><L><Q><E><Y><Q><L><P><Y><Q><R><V><L><P><L><P><I><F><T><P><A><K><M><G><A><T><K><E><E><R><E... | Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.<BOP> | O15273 |
Q0HZP9 | UBIB_SHESR | Ubiquinone biosynthesis protein UbiB | Shewanella | <M><T><L><A><S><I><R><R><G><Y><H><V><I><K><T><L><L><Q><Y><G><L><D><D><V><L><P><P><K><M><T><P><W><Y><F><K><L><A><R><N><S><L><F><W><I><R><N><K><H><K><G><K><S><G><G><E><R><L><K><L><A><M><Q><E><L><G><P><V><Y><I><K><L><G><Q><M><L><S><T><R><R><D><L><L><S><D><E><W><A><N><E><L><A><M><L><Q><D><K><V><P><P><F><D><G><A><L><A><R><Q... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | Q0HZP9 |
Q15035 | TRAM2_HUMAN | Translocating chain-associated membrane protein 2 | Homo | <M><A><F><R><R><R><T><K><S><Y><P><L><F><S><Q><E><F><V><I><H><N><H><A><D><I><G><F><C><L><V><L><C><V><L><I><G><L><M><F><E><V><T><A><K><T><A><F><L><F><I><L><P><Q><Y><N><I><S><V><P><T><A><D><S><E><T><V><H><Y><H><Y><G><P><K><D><L><V><T><I><L><F><Y><I><F><I><T><I><I><L><H><A><V><V><Q><E><Y><I><L><D><K><I><S><K><R><L><H><L><S... | Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones invol... | Q15035 |
P51854 | TKTL1_HUMAN | Transketolase-related protein | Homo | <M><A><D><A><E><A><R><A><E><F><P><E><E><A><R><P><D><R><G><T><L><Q><V><L><Q><D><M><A><S><R><L><R><I><H><S><I><R><A><T><C><S><T><S><S><G><H><P><T><S><C><S><S><S><S><E><I><M><S><V><L><F><F><Y><I><M><R><Y><K><Q><S><D><P><E><N><P><D><N><D><R><F><V><L><A><K><R><L><S><F><V><D><V><A><T><G><W><L><G><Q><G><L><G><V><A><C><G><M><A... | Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.<BOP> | P51854 |
Q4L5T8 | Y1678_STAHJ | UPF0122 protein SH1678 | Staphylococcus | <M><G><K><N><D><L><V><K><T><L><R><M><N><Y><L><F><D><F><Y><Q><T><L><L><T><E><K><Q><R><N><Y><M><E><L><F><Y><L><R><D><Y><S><L><S><E><I><A><E><T><F><D><V><S><R><Q><A><V><Y><D><N><I><R><R><T><G><D><L><V><E><D><Y><E><A><K><L><N><L><Y><E><K><F><E><Q><R><R><K><I><Y><D><D><M><K><Q><T><L><N><D><S><K><K><L><E><Q><Y><I><N><Q><L><E... | Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.<BOP> | Q4L5T8 |
B9DUQ2 | TRHO_STRU0 | tRNA hydroxylation protein O | Streptococcus | <M><S><E><K><I><R><V><L><L><Y><Y><K><Y><V><P><I><E><D><A><Q><A><Y><A><A><K><H><L><E><F><C><K><S><I><G><L><K><G><R><I><I><I><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><W><V><H><S><D><E><R><F><S><D><L><W><F><K><M><D><E><E><E><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><Q><F><D... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | B9DUQ2 |
Q96WV0 | UREG_SCHPO | Uncharacterized urease accessory protein ureG-like | Schizosaccharomyces | <M><A><I><P><F><L><H><K><G><G><S><D><D><S><T><H><H><H><T><H><D><Y><D><H><H><N><H><D><H><H><G><H><D><H><H><S><H><D><S><S><S><N><S><S><S><E><A><A><R><L><Q><F><I><Q><E><H><G><H><S><H><D><A><M><E><T><P><G><S><Y><L><K><R><E><L><P><Q><F><N><H><R><D><F><S><R><R><A><F><T><I><G><V><G><G><P><V><G><S><G><K><T><A><L><L><L><Q><L><C... | Probably facilitates nickel incorporation.<BOP> | Q96WV0 |
Q4LCT2 | TXA5_ANDAU | Toxin-like peptide AaF1CA5 | Androctonus | <M><M><K><L><M><L><F><S><I><I><V><I><L><F><S><L><I><G><S><I><H><G><A><D><V><P><G><N><Y><P><L><D><S><S><D><D><T><Y><L><C><A><P><L><G><E><N><P><F><C><I><K><I><C><R><K><H><G><V><K><Y><G><L><M><L><R><L><P><C><W><C><E><Y><F><G><K><I><K><N><V><K><I> | Probable neurotoxin that inhibits ion channels.<BOP> | Q4LCT2 |
Q7W419 | UREF_BORPA | Urease accessory protein UreF | Bordetella | <M><H><L><S><S><P><A><L><P><I><G><G><F><S><Y><S><Q><G><L><E><A><A><I><E><L><G><L><V><H><D><E><A><S><T><L><A><W><I><E><S><Q><L><V><T><V><M><A><R><A><E><A><P><L><W><C><L><L><F><E><A><W><R><A><G><D><D><A><A><A><H><G><W><N><Q><W><F><H><A><S><R><E><T><R><E><L><R><Q><E><T><E><Q><M><G><R><S><L><A><R><L><A><Q><E><L><G><W><G><T... | Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP> | Q7W419 |
Q03ER2 | TGT_PEDPA | tRNA-guanine transglycosylase | Pediococcus | <M><E><P><A><I><K><Y><R><L><I><K><T><D><K><H><T><G><A><R><L><G><E><I><I><T><P><H><G><T><F><P><T><P><I><F><M><P><V><G><T><Q><A><T><V><K><A><M><S><P><E><E><L><E><D><L><G><A><D><I><I><L><S><N><T><Y><H><L><W><V><R><P><G><E><D><I><V><K><E><G><G><G><L><H><Q><F><M><N><W><K><K><G><I><L><T><D><S><G><G><F><Q><V><F><S><L><A><K><L... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q03ER2 |
P60590 | WGRTX_GRARO | Omega-grammotoxin SIA | Grammostola | <M><K><A><Q><I><F><V><V><V><L><G><L><A><A><L><S><V><L><C><Y><G><S><E><A><D><E><S><A><L><H><E><E><I><F><Q><L><L><A><A><S><D><E><V><P><K><P><Q><E><R><D><C><V><R><F><W><G><K><C><S><Q><T><S><D><C><C><P><H><L><A><C><K><S><K><W><P><R><N><I><C><V><W><D><G><S><V><G><K> | Inhibits P/Q- (Cav2.1/CACNA1A) and N-type (Cav2.2/CACNA1B) voltage-gated calcium channel by modifying voltage-dependent gating . It selectively and reversibly blocks the calcium channels coupled to glutamate release . Also inhibits potassium channels (Kv2.1/KCNB1) with lower affinity . Has also been shown to weakly inh... | P60590 |
Q0BU78 | YIDC_GRABC | Membrane protein YidC | Granulibacter | <M><D><Q><K><R><L><F><L><A><I><A><I><S><L><G><I><L><L><G><F><Q><G><L><Y><R><H><F><V><P><E><P><P><A><A><A><R><T><A><T><N><A><G><Q><G><K><P><N><N><T><L><G><A><V><P><T><D><A><T><A><S><Q><S><P><P><P><K><E><G><A><R><L><A><V><D><A><P><R><V><K><G><S><I><S><L><V><G><A><R><F><D><D><L><V><L><R><D><Y><H><E><T><V><D><K><N><S><P><L... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | Q0BU78 |
P13528 | UNC86_CAEEL | Uncoordinated protein 86 | Caenorhabditis | <M><Q><N><T><A><P><V><P><T><T><T><T><A><S><K><M><Q><P><F><N><N><S><L><F><G><S><F><D><D><P><I><L><N><A><R><A><A><Q><V><A><L><A><D><I><D><V><K><N><V><P><Q><L><T><N><P><L><M><R><P><H><D><M><F><S><Y><S><N><Y><F><S><G><I><H><D><T><S><A><A><T><N><I><Y><Q><G><L><P><S><S><S><E><P><F><D><A><S><V><V><V><P><T><S><S><D><D><Q><M><T... | Transcription factor required for correct cell fate determination and differentiation in diverse neuronal cell lineages where it plays a role in specifying the fate of daughter cells during cell divisions . Involved in sensory neuron production and function . Binds both alone and with mec-3 to the mec-3 promoter to ini... | P13528 |
O94888 | UBXN7_HUMAN | UBX domain-containing protein 7 | Homo | <M><A><A><H><G><G><S><A><A><S><S><A><L><K><G><L><I><Q><Q><F><T><T><I><T><G><A><S><E><S><V><G><K><H><M><L><E><A><C><N><N><N><L><E><M><A><V><T><M><F><L><D><G><G><G><I><A><E><E><P><S><T><S><S><A><S><V><S><T><V><R><P><H><T><E><E><E><V><R><A><P><I><P><Q><K><Q><E><I><L><V><E><P><E><P><L><F><G><A><P><K><R><R><R><P><A><R><S><I... | Ubiquitin-binding adapter that links a subset of NEDD8-associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates.<BOP> | O94888 |
Q9FNB3 | Y5360_ARATH | Putative BTB/POZ domain-containing protein At5g13600 | Arabidopsis | <M><A><S><L><K><L><G><S><K><S><E><V><F><H><L><S><G><H><T><W><L><C><K><T><G><L><K><P><D><V><M><I><Q><V><V><D><E><S><F><H><L><H><K><F><P><L><L><S><R><S><G><Y><L><E><T><L><F><S><K><A><S><E><T><T><C><V><A><Q><L><H><D><I><P><G><G><P><E><T><F><L><L><V><A><K><F><C><Y><G><V><R><I><E><V><T><P><E><N><A><V><S><L><R><C><A><A><E><Y... | May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP> | Q9FNB3 |
B1MYE1 | YBEY_LEUCK | Endoribonuclease YbeY | Leuconostoc | <M><D><L><A><I><I><D><Q><T><H><D><G><V><S><R><Y><H><H><D><L><V><E><S><V><L><N><F><A><G><E><A><L><K><L><P><V><N><T><E><M><S><V><T><F><V><N><N><D><E><I><Q><R><Y><N><R><D><Y><R><G><V><D><K><P><T><D><V><I><S><F><A><I><E><E><G><E><D><D><F><N><I><I><S><D><D><A><W><T><E><D><I><A><K><N><I><G><D><I><I><V><S><V><D><I><I><G><A><Q... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | B1MYE1 |
Q2P0V3 | TPIS_XANOM | Triose-phosphate isomerase | Xanthomonas | <M><R><R><K><I><V><A><G><N><W><K><L><H><G><S><R><A><F><A><T><E><L><V><A><K><L><A><A><H><M><P><L><E><G><I><D><V><V><I><L><P><P><L><P><Y><L><G><D><L><I><E><D><F><E><A><H><H><L><S><F><G><A><Q><D><V><S><S><N><E><K><G><A><Y><T><G><E><V><S><A><S><M><L><V><D><V><G><A><G><Y><G><L><V><G><H><S><E><R><R><Q><Y><H><Q><E><S><S><E><L... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q2P0V3 |
Q5TC79 | ZBT37_HUMAN | Zinc finger and BTB domain-containing protein 37 | Homo | <M><E><K><G><G><N><I><Q><L><E><I><P><D><F><S><N><S><V><L><S><H><L><N><Q><L><R><M><Q><G><R><L><C><D><I><V><V><N><V><Q><G><Q><A><F><R><A><H><K><V><V><L><A><A><S><S><P><Y><F><R><D><H><M><S><L><N><E><M><S><T><V><S><I><S><V><I><K><N><P><T><V><F><E><Q><L><L><S><F><C><Y><T><G><R><I><C><L><Q><L><A><D><I><I><S><Y><L><T><A><A><S... | May be involved in transcriptional regulation.<BOP> | Q5TC79 |
A1SJ31 | TYSY_NOCSJ | Thymidylate synthase | Nocardioides | <M><R><A><Y><L><D><L><L><Q><R><V><V><D><E><G><V><P><K><G><D><R><T><G><T><G><T><L><S><V><F><G><H><Q><M><R><F><D><L><R><A><G><F><P><L><V><T><T><K><K><V><H><T><R><S><V><F><G><E><L><L><W><F><L><R><G><D><T><N><V><K><W><L><Q><D><R><G><I><T><I><W><D><E><W><A><D><E><Q><G><D><L><G><P><V><Y><G><Y><Q><W><R><S><W><P><T><P><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | A1SJ31 |
Q746Q2 | YIDC_GEOSL | Membrane protein YidC | Geobacter | <M><E><K><R><A><L><I><A><V><V><L><S><I><L><F><F><Y><G><Y><T><A><L><F><S><P><P><P><K><E><T><P><K><P><V><A><T><A><T><Q><S><Q><P><A><Q><Q><V><T><A><A><P><V><P><V><A><V><P><A><Q><P><Q><P><A><V><A><A><R><D><V><S><V><D><T><P><A><Y><S><V><T><F><S><T><Q><G><G><S><I><K><R><L><D><L><K><R><Y><H><E><T><A><G><P><G><G><K><N><V><T><L... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | Q746Q2 |
B7VMM4 | YCIB_VIBA3 | Inner membrane-spanning protein YciB | Vibrio | <M><K><Q><I><L><D><F><I><P><L><I><I><F><F><A><L><Y><K><M><Y><D><I><Y><T><A><T><G><A><L><I><V><A><S><A><V><Q><I><I><L><T><Y><F><I><Y><K><K><V><E><K><M><Q><V><I><T><F><L><M><V><A><V><F><G><G><M><T><I><F><L><H><D><D><N><F><I><K><W><K><V><T><I><V><Y><A><L><F><A><I><G><L><T><V><S><H><I><M><G><K><S><A><I><K><G><M><L><G><K><E... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | B7VMM4 |
P75691 | YAHK_ECOLI | Zinc-dependent alcohol dehydrogenase YahK | Escherichia | <M><K><I><K><A><V><G><A><Y><S><A><K><Q><P><L><E><P><M><D><I><T><R><R><E><P><G><P><N><D><V><K><I><E><I><A><Y><C><G><V><C><H><S><D><L><H><Q><V><R><S><E><W><A><G><T><V><Y><P><C><V><P><G><H><E><I><V><G><R><V><V><A><V><G><D><Q><V><E><K><Y><A><P><G><D><L><V><G><V><G><C><I><V><D><S><C><K><H><C><E><E><C><E><D><G><L><E><N><Y><C... | Catalyzes the reduction of a wide range of aldehydes into their corresponding alcohols. Has a strong preference for NADPH over NADH as the electron donor. Cannot use a ketone as substrate. Is a major source of NADPH-dependent aldehyde reductase activity in E.coli. The in vivo functions of YahK has yet to be determined.... | P75691 |
Q26503 | TPM_SCHHA | Tropomyosin | Schistosoma | <M><D><G><I><K><K><K><M><I><A><M><K><L><E><K><E><N><A><M><E><R><A><V><Q><Y><E><E><L><L><K><K><K><E><E><E><R><E><K><R><E><S><E><I><A><E><L><N><T><K><M><K><Q><A><Q><I><D><C><D><E><V><Q><E><T><L><Q><E><Q><M><N><K><L><E><E><T><D><K><R><A><T><N><A><E><A><E><V><A><A><M><T><R><R><I><R><L><L><E><E><D><L><E><V><S><S><S><R><L><T... | Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.<BOP> | Q26503 |
Q31TC4 | ULAA_SHIBS | Ascorbate-specific permease IIC component UlaA | Shigella | <M><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><D><R><M><G><D><A><Y><S><W><V><G><Y><A><V><L><L><A><L><A><L><N><I... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | Q31TC4 |
Q3SYZ6 | XYLB_BOVIN | Xylulose kinase | Bos | <M><A><E><R><A><A><R><H><C><C><L><G><W><D><F><S><T><Q><Q><V><K><V><V><A><V><D><A><E><L><S><V><F><Y><E><D><S><V><H><F><D><R><D><L><V><E><F><G><T><Q><G><G><V><H><V><H><K><D><G><L><T><V><T><S><P><V><L><M><W><V><Q><A><L><D><I><I><L><E><K><M><K><A><S><G><F><D><F><S><Q><V><L><A><L><S><G><A><G><Q><Q><H><G><S><V><Y><W><K><T><G... | Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.<BOP> | Q3SYZ6 |
Q92BC5 | TPX_LISIN | Thioredoxin-dependent peroxiredoxin | Listeria | <M><T><Q><V><T><F><K><H><N><P><V><T><L><V><G><T><E><R><K><V><G><D><K><A><P><N><F><T><V><V><N><R><D><L><E><E><V><T><L><H><D><Y><D><G><K><V><R><L><I><S><V><V><P><S><I><D><T><S><V><C><S><T><Q><T><R><K><F><N><E><E><A><S><N><L><D><N><T><V><V><L><T><I><S><V><D><L><P><F><A><Q><K><K><W><C><A><A><E><G><L><P><N><A><I><T><L><S><D... | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP> | Q92BC5 |
P42461 | THIX_CORGL | Thiamine biosynthesis protein X | Corynebacterium | <M><S><I><S><R><T><V><F><G><I><A><A><T><A><A><L><S><A><A><L><V><A><C><S><P><P><H><Q><Q><D><S><P><V><Q><R><T><N><E><I><L><T><T><S><Q><N><P><T><S><A><S><S><T><S><T><S><S><A><T><T><T><S><S><A><P><V><E><E><D><V><E><I><V><V><S><P><A><A><L><V><D><G><E><Q><V><T><F><E><I><S><G><L><D><P><E><G><G><Y><Y><A><A><I><C><D><S><V><A><N... | Is necessary for biosynthesis of the 4-methyl-5-(beta-hydroxyethyl)thiazol component from which thiamine is formed.<BOP> | P42461 |
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