accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q65WC1 | TSAC_MANSM | tRNA threonylcarbamoyladenosine biosynthesis protein TsaC | Basfia | <M><E><L><A><Q><I><V><E><R><L><K><K><N><E><V><V><A><Y><P><T><E><A><V><F><G><L><G><C><N><P><N><S><K><S><A><V><E><K><L><L><I><L><K><Q><R><P><V><E><K><G><L><I><L><V><A><H><K><L><D><L><L><L><P><F><I><D><E><S><R><L><K><Q><S><H><W><Q><L><L><T><Q><Q><Y><D><C><P><T><T><W><V><V><P><A><K><L><S><V><P><K><F><I><T><G><Q><F><D><S><V... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP> | Q65WC1 |
A6TFL2 | TDH_KLEP7 | L-threonine 3-dehydrogenase | Klebsiella | <M><K><A><L><S><K><L><K><A><E><E><G><I><W><M><T><D><V><P><E><P><E><V><G><H><N><D><L><L><I><K><I><R><K><T><A><I><C><G><T><D><V><H><I><Y><N><W><D><E><W><S><Q><K><T><I><P><V><P><M><V><V><G><H><E><Y><V><G><E><V><V><G><I><G><Q><E><V><R><G><F><K><I><G><D><R><V><S><G><E><G><H><I><T><C><G><H><C><R><N><C><R><A><G><R><T><H><L><C... | Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.<BOP> | A6TFL2 |
Q223B1 | UBID_ALBFT | Polyprenyl p-hydroxybenzoate decarboxylase | Rhodoferax | <M><A><Y><R><D><L><R><D><F><I><T><Q><L><E><H><L><G><E><L><K><R><V><Q><A><E><V><S><P><Y><L><E><M><T><A><L><C><D><R><T><L><R><A><G><G><P><A><L><L><F><E><N><P><T><G><H><N><T><P><V><L><G><N><L><F><G><T><T><R><R><V><A><L><G><M><G><V><N><D><V><S><E><L><R><Q><F><G><H><V><L><A><S><L><K><E><P><E><A><P><K><G><F><K><E><L><M><G><L... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q223B1 |
Q2FKX5 | TRPD_METHJ | Anthranilate phosphoribosyltransferase | Methanospirillum | <M><I><Q><D><T><I><R><K><V><V><S><M><Q><D><L><A><P><D><E><A><R><D><L><M><T><S><I><A><D><G><K><V><T><D><A><Q><I><G><S><I><L><T><A><L><S><M><K><G><V><T><A><H><E><I><T><A><F><A><H><V><L><R><D><R><A><V><Q><L><K><T><D><T><S><G><T><F><V><D><T><C><G><T><G><G><D><G><A><H><T><F><N><I><S><T><A><A><A><L><V><A><A><A><A><G><V><R><V... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q2FKX5 |
A6ZVR0 | URM1_YEAS7 | Ubiquitin-related modifier 1 | Saccharomyces | <M><V><N><V><K><V><E><F><L><G><G><L><D><A><I><F><G><K><Q><R><V><H><K><I><K><M><D><K><E><D><P><V><T><V><G><D><L><I><D><H><I><V><S><T><M><I><N><N><P><N><D><V><S><I><F><I><E><D><D><S><I><R><P><G><I><I><T><L><I><N><D><T><D><W><E><L><E><G><E><K><D><Y><I><L><E><D><G><D><I><I><S><F><T><S><T><L><H><G><G> | Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2... | A6ZVR0 |
P43349 | TCTP_SOLTU | p23 | Solanum | <M><L><V><Y><Q><D><L><L><T><G><D><E><L><L><S><D><S><F><P><Y><K><E><I><Q><N><G><M><L><W><E><V><Q><G><K><W><V><V><Q><G><A><V><D><V><N><I><G><A><N><P><S><A><E><G><G><G><E><D><E><G><V><D><D><Q><A><V><K><V><V><D><I><V><D><T><F><R><L><Q><E><Q><P><A><F><D><K><K><Q><F><V><T><Y><I><K><R><Y><I><K><N><L><T><P><K><L><E><G><E><A><Q... | Involved in calcium binding and microtubule stabilization.<BOP> | P43349 |
A6UWW4 | TRM56_META3 | tRNA ribose 2'-O-methyltransferase aTrm56 | Methanococcus | <M><V><V><E><V><L><R><L><G><H><R><W><G><R><D><K><R><I><S><T><H><V><A><L><T><S><R><A><L><G><A><D><K><I><L><F><V><S><N><D><D><H><V><K><D><S><V><N><R><I><V><E><Q><W><G><G><D><F><K><F><D><V><V><D><S><W><K><Q><Y><I><W><S><F><K><K><N><N><G><I><V><I><H><L><T><M><Y><G><E><N><I><N><E><I><M><K><K><I><I><E><K><R><Q><E><G><K><D><S... | Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.<BOP> | A6UWW4 |
Q491V9 | UBID_BLOPB | Polyprenyl p-hydroxybenzoate decarboxylase | Candidatus Blochmannia | <M><K><Y><K><D><L><R><D><F><I><K><I><L><E><H><R><G><D><L><K><R><I><K><F><P><I><N><P><D><L><E><I><T><E><I><A><D><R><T><I><K><S><G><G><P><A><L><F><F><E><N><P><T><G><Y><T><I><P><V><L><C><N><L><F><G><T><P><N><R><I><A><L><G><M><G><K><E><S><I><L><S><L><R><D><V><G><K><L><L><A><F><L><R><E><P><E><L><P><T><G><V><H><D><F><F><S><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q491V9 |
O95801 | TTC4_HUMAN | Tetratricopeptide repeat protein 4 | Homo | <M><E><Q><P><G><Q><D><P><T><S><D><D><V><M><D><S><F><L><E><K><F><Q><S><Q><P><Y><R><G><G><F><H><E><D><Q><W><E><K><E><F><E><K><V><P><L><F><M><S><R><A><P><S><E><I><D><P><R><E><N><P><D><L><A><C><L><Q><S><I><I><F><D><E><E><R><S><P><E><E><Q><A><K><T><Y><K><D><E><G><N><D><Y><F><K><E><K><D><Y><K><K><A><V><I><S><Y><T><E><G><L><K... | May act as a co-chaperone for HSP90AB1 . Promotes Sendai virus (SeV)-induced host cell innate immune responses .<BOP> | O95801 |
P0CD94 | UQCC3_RAT | Ubiquinol-cytochrome-c reductase complex assembly factor 3 | Rattus | <M><E><A><A><R><K><A><L><A><V><V><A><V><L><G><A><G><G><G><V><G><S><I><L><F><A><L><V><T><P><G><E><L><Q><K><Q><L><M><L><Q><E><M><P><E><R><D><S><R><R><R><D><E><A><V><R><T><K><E><L><V><M><A><T><L><K><D><A><A><A><T><K><E><N><V><A><W><R><R><N><W><T><V><R><G><D><G><R><S><A> | Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding pr... | P0CD94 |
A2RI47 | THIT_LACLM | Thiamine ECF transporter S component ThiT | Lactococcus cremoris subsp. cremoris | <M><S><N><S><K><F><N><V><R><L><L><T><E><I><A><F><M><A><A><L><A><F><I><I><S><L><I><P><N><T><V><Y><G><W><I><I><V><E><I><A><C><I><P><I><L><L><L><S><L><R><R><G><L><T><A><G><L><V><G><G><L><I><W><G><I><L><S><M><I><T><G><H><A><Y><I><L><S><L><S><Q><A><F><L><E><Y><L><V><A><P><V><S><L><G><I><A><G><L><F><R><Q><K><T><A><P><L><K><L... | Probably a thiamine-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic s... | A2RI47 |
Q6YQR9 | YQGF_ONYPE | Putative pre-16S rRNA nuclease | Candidatus Phytoplasma asteris | <M><L><K><C><Q><N><N><A><S><L><G><L><D><L><G><E><K><T><L><G><I><A><L><S><Q><T><G><I><I><A><Q><N><L><K><T><I><F><F><A><T><H><K><Y><D><R><L><I><A><P><L><Q><E><I><I><F><Q><Y><Q><I><K><T><I><V><L><G><Y><P><K><H><M><N><N><D><I><G><I><K><A><K><I><S><S><D><F><K><K><T><L><E><N><K><F><E><Q><V><K><V><I><L><W><D><E><R><L><S><T><V... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | Q6YQR9 |
P24421 | VSDF_SALDU | Virulence protein VsdF | Salmonella | <M><L><R><A><T><K><V><C><I><Y><P><T><P><E><Q><A><E><H><L><N><A><Q><F><G><A><V><R><F><V><Y><S><K><S><L><H><I><K><K><H><A><Y><Q><R><H><G><V><S><L><T><P><R><K><D><I><K><P><L><L><A><V><A><K><K><F><R><K><F><R><K><F><R><K><Y><A><W><L><K><E><Y><D><S><I><A><L><Q><Q><A><V><I><N><L><D><V><A><F><S><N><C><F><N><P><K><L><K><A><R><F... | Expressed but non-essential protein, involved in the virulence of Salmonellas.<BOP> | P24421 |
Q5FNP1 | UVRC_GLUOX | Excinuclease ABC subunit C | Gluconobacter | <M><T><D><L><P><P><H><S><S><H><H><P><A><D><Q><G><E><P><L><V><P><A><E><K><K><Q><G><V><E><A><I><R><E><A><L><K><T><I><P><Y><S><P><G><V><Y><R><M><L><S><E><K><G><E><V><L><Y><V><G><K><A><L><S><L><K><K><R><V><S><S><Y><I><R><I><N><Q><L><P><E><R><L><R><R><M><V><S><M><T><V><S><M><E><I><V><I><T><R><T><E><A><D><A><L><L><L><E><A><N... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q5FNP1 |
K7WDC8 | TS21I_MAIZE | Terpene synthase 21 | Zea | <M><G><E><R><A><N><F><L><K><G><E><V><R><K><K><F><E><A><A><A><M><S><A><I><D><A><A><M><L><V><D><A><V><V><H><L><G><I><D><H><C><F><R><E><E><I><A><T><A><L><R><S><V><H><E><D><E><E><G><E><F><G><S><C><D><D><L><H><T><V><A><V><R><F><L><V><L><R><Q><H><G><L><W><V><S><A><D><V><F><D><K><F><R><D><D><K><G><S><F><S><K><S><L><L><C><S><N... | Inactive selinene synthase.<BOP> | K7WDC8 |
P06708 | TNNC2_ASTLP | Troponin C, isotype gamma | Astacus | <M><D><T><L><D><E><E><Q><L><S><A><L><K><K><A><F><D><S><F><D><T><D><S><K><G><F><I><T><P><E><T><V><G><V><I><L><R><M><M><G><V><K><I><S><E><K><N><L><Q><Q><V><I><A><E><T><D><E><D><G><S><G><E><L><E><F><E><E><F><V><E><L><A><A><K><F><L><I><E><E><D><E><E><A><L><K><A><E><L><K><E><A><F><R><I><Y><D><K><G><G><D><G><Y><I><T><T><D><V... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P06708 |
Q03QE7 | TRMB_LEVBA | tRNA(m7G46)-methyltransferase | Levilactobacillus | <M><R><V><R><N><K><P><W><A><K><G><Y><M><A><D><H><L><D><R><L><V><V><E><P><E><P><L><K><G><N><W><Q><S><R><F><P><S><N><Q><P><L><F><V><E><I><G><T><G><K><G><Q><F><I><I><E><M><A><R><Q><H><P><D><R><N><F><I><G><I><E><I><Q><T><S><V><I><A><V><A><L><K><G><V><V><N><S><G><L><T><N><I><Q><L><V><H><T><D><G><E><A><I><N><T><F><F><E><A><G... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | Q03QE7 |
Q0KEH6 | UBIE_CUPNH | Demethylmenaquinone methyltransferase | Cupriavidus | <M><S><E><T><H><F><G><F><E><K><V><D><E><A><E><K><A><D><K><V><A><G><V><F><H><S><V><A><S><K><Y><D><V><M><N><D><L><M><S><G><G><M><H><R><L><W><K><M><F><T><I><A><Q><A><G><V><R><P><G><H><K><V><L><D><I><A><G><G><T><G><D><L><A><K><A><F><A><K><Q><A><G><P><T><G><E><V><W><L><T><D><I><N><E><S><M><L><R><V><G><R><D><R><L><L><N><K><G... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | Q0KEH6 |
Q9CFG8 | XYLB_LACLA | Xylulose kinase | Lactococcus | <M><T><Y><V><L><G><I><D><L><G><T><S><S><L><K><G><I><L><M><D><E><V><G><N><L><I><T><T><K><S><A><E><Y><Q><I><D><T><P><K><Q><G><Y><S><E><Q><R><P><E><Y><W><I><V><A><L><E><S><V><L><T><G><L><S><V><E><I><S><D><F><G><Q><Q><L><A><G><I><S><F><S><G><Q><M><H><S><L><V><V><L><D><D><N><N><K><P><V><Y><P><A><I><L><W><N><D><V><R><T><S><K... | Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.<BOP> | Q9CFG8 |
Q65JH8 | TRUB_BACLD | tRNA-uridine isomerase | Bacillus | <M><Y><N><G><V><L><L><L><H><K><P><V><G><M><T><S><H><D><C><V><M><K><I><R><K><L><L><K><T><K><K><V><G><H><T><G><T><L><D><P><E><V><S><G><V><L><P><I><C><V><G><R><A><T><K><I><V><E><Y><L><T><E><K><S><K><T><Y><D><A><E><V><T><L><G><C><S><T><E><T><E><D><Q><T><G><E><V><T><E><K><K><P><V><L><A><P><P><D><E><Q><T><V><Q><S><V><L><R><S... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q65JH8 |
Q06417 | TDA5_YEAST | Topoisomerase I damage affected protein 5 | Saccharomyces | <M><N><I><D><C><L><C><R><W><V><V><L><P><L><L><R><Y><P><L><L><V><A><L><V><L><R><W><S><L><S><D><S><I><S><I><C><L><T><I><Y><T><L><L><I><N><A><F><L><I><A><N><S><Y><I><K><R><S><G><Q><V><A><W><K><S><L><R><E><F><K><N><G><I><V><L><I><T><G><G><S><K><G><L><G><R><A><I><V><S><Q><L><L><Q><D><Y><S><N><L><T><I><L><N><V><D><I><C><P><S... | Involved in the resistance to DNA-damaging agents.<BOP> | Q06417 |
Q4L4I5 | UVRB_STAHJ | Excinuclease ABC subunit B | Staphylococcus | <M><V><E><H><Y><P><F><K><L><N><S><E><F><D><P><Q><G><D><Q><P><Q><A><I><E><K><I><V><K><G><V><K><E><G><K><R><H><Q><T><L><L><G><A><T><G><T><G><K><T><F><T><M><S><N><V><I><K><E><V><G><K><P><T><L><I><I><A><H><N><K><T><L><A><G><Q><L><Y><S><E><F><K><E><F><F><P><E><N><R><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><S><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q4L4I5 |
P06015 | VSA1_TRYBB | Expression-linked copy | Trypanosoma | <M><V><T><K><E><R><N><A><A><L><K><I><V><M><L><V><A><S><A><L><T><L><H><P><Q><Q><A><L><A><Q><T><A><G><R><P><L><A><D><V><V><G><K><T><L><C><T><Y><S><K><T><A><K><R><Q><A><A><N><L><A><Q><T><L><Q><R><A><S><S><A><A><K><Q><S><R><Q><A><Q><Q><L><A><A><L><A><L><A><K><L><P><D><Y><K><E><A><A><A><T><L><L><I><Y><A><T><H><K><I><Q><D><A... | VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.<BOP> | P06015 |
P05471 | YKP5_KLULA | Uncharacterized killer plasmid pGKl-2 protein 5 | Kluyveromyces | <M><I><Y><D><K><I><D><T><K><L><I><K><L><G><K><T><N><K><F><S><G><E><E><E><K><S><I><T><S><L><Y><Y><E><D><E><S><F><E><F><S><F><K><N><K><Y><V><K><I><T><K><I><E><T><N><A><Y><G><K><K><F><V><T><I><K><S><K><L><Y><A><D><I><V><E><K><V><A><K><E><L><D><A><V><S><P><I><L><S><D><G><S><F><R><A><T><I><N><D><A><T><S><F><S><K><D><V><G><E... | The presence of the two linear plasmids, termed pGKL1 and pGKL2, in strains of Kluyveromyces lactis confers the killer phenotype to the host cell, by promoting the secretion of a toxin able to inhibit the growth of sensitive strains.<BOP> | P05471 |
Q5HQX0 | UVRB_STAEQ | Excinuclease ABC subunit B | Staphylococcus | <M><V><E><H><V><P><F><K><L><K><S><E><F><E><P><Q><G><D><Q><P><Q><A><I><Q><K><I><V><D><G><V><N><E><G><K><R><H><Q><T><L><L><G><A><T><G><T><G><K><T><F><T><M><S><N><V><I><K><E><V><G><K><P><T><L><I><I><A><H><N><K><T><L><A><G><Q><L><Y><S><E><F><K><E><F><F><P><E><N><R><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><S><T... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q5HQX0 |
Q9RJ68 | TATA_STRCO | Sec-independent protein translocase protein TatA | Streptomyces albidoflavus group | <M><F><G><R><L><G><A><P><E><I><I><L><I><L><V><V><I><I><L><L><F><G><A><K><K><L><P><D><M><A><R><S><L><G><K><S><A><R><I><L><K><S><E><A><K><A><M><K><S><E><A><K><A><D><D><A><A><P><A><D><P><P><N><P><E><Q><S><A><A><Q><R><T><I><Q><A><A><P><G><D><V><T><S><S><R><P><V><T><E><P><T><D><T><T><K><R> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | Q9RJ68 |
Q7PYU6 | ZGPAT_ANOGA | Zinc finger CCCH-type with G patch domain-containing protein | Anopheles | <M><S><V><D><E><L><N><Q><S><I><L><Q><Y><K><E><Q><L><E><Q><I><A><Q><A><L><Q><L><T><R><D><E><T><E><R><S><E><L><N><K><L><K><S><D><L><I><E><L><L><E><L><T><V><E><S><L><A><A><T><S><D><D><D><D><A><P><D><T><A><G><R><A><P><P><A><T><A><D><N><P><I><D><D><E><F><A><L><F><M><R><E><I><K><E><L><Q><T><E><D><S><A><A><G><E><Q><A><G><E><Q... | Transcription repressor.<BOP> | Q7PYU6 |
Q4V7E0 | TRMO_RAT | tRNA methyltransferase O | Rattus | <M><R><G><L><E><K><Q><G><P><S><A><T><A><A><P><C><G><C><A><Q><P><A><L><E><T><G><N><L><L><T><E><P><I><G><Y><L><E><S><C><F><S><A><K><I><G><T><P><R><Q><P><S><I><C><S><Q><S><R><A><C><L><K><I><R><K><S><I><F><N><N><P><E><H><S><L><M><G><L><E><Q><F><S><H><V><W><I><L><F><V><F><H><K><N><G><H><L><N><Y><K><A><K><V><Q><P><P><R><L><N... | S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding abil... | Q4V7E0 |
A4SGX9 | TAL_CHLPM | Probable transaldolase | Chlorobium | <M><K><F><F><I><D><T><A><D><L><D><E><I><R><S><A><A><E><L><G><M><L><D><G><V><T><T><N><P><S><L><I><A><K><I><V><K><D><P><S><N><F><T><R><T><D><F><F><D><H><I><A><A><I><C><D><L><V><D><G><P><V><S><A><E><V><T><S><L><D><T><A><S><M><I><K><E><G><E><A><L><A><A><I><H><D><N><V><V><V><K><C><P><L><T><I><D><G><L><K><A><I><R><H><L><S><E... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | A4SGX9 |
F1R013 | ZDHC9_DANRE | Zinc finger DHHC domain-containing protein 9 | Danio | <M><S><A><V><M><I><T><R><K><I><T><R><K><W><E><K><L><P><G><K><N><T><F><C><C><D><G><R><V><M><M><A><R><Q><K><G><V><F><Y><L><T><L><F><L><I><V><G><T><C><S><L><F><F><A><F><E><C><P><Y><L><A><V><H><L><S><P><A><I><P><V><F><A><V><L><L><F><V><F><V><M><A><M><L><L><R><T><S><F><S><D><P><G><V><L><P><R><A><L><P><E><E><A><N><F><I><E><M... | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates.<BOP> | F1R013 |
P20005 | VSP1_OVOOK | Snake venom serine protease | Ovophis | <V><I><G><G><D><E><C><N><I><N><E><H><R><F><L><A><A><L><Y><D> | Thrombin-like snake venom serine protease that releases specifically fibrinopeptide B from fibrinogen (FGB) to form fibrin clots. Shows a preferential cleavage at Arg-|-Gly bonds in fibrinogen beta chains. Cleaves fibrinogen beta chains preferentially to alpha chains.<BOP> | P20005 |
B7HH02 | TRPA_BACC4 | Tryptophan synthase alpha chain | Bacillus cereus group | <M><G><V><E><K><I><K><A><A><F><E><N><G><K><K><A><F><I><P><Y><V><M><G><G><D><G><G><F><E><K><L><K><E><R><I><R><F><L><D><E><A><G><A><S><I><V><E><I><G><I><P><F><S><D><P><V><A><D><G><P><T><I><Q><R><A><G><K><R><A><L><D><S><G><V><T><V><K><G><I><F><Q><A><L><I><E><V><R><K><E><V><Q><I><P><F><V><L><M><T><Y><L><N><P><V><L><A><F><G... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B7HH02 |
Q57637 | Y173_METJA | Putative transcriptional regulatory protein MJ0173 | Methanocaldococcus | <M><V><E><D><S><F><L><T><D><T><Q><I><K><V><L><K><L><R><K><K><G><L><T><Q><E><E><I><A><K><M><L><G><T><S><R><A><N><I><S><M><I><E><K><R><A><K><E><N><I><K><K><A><Y><N><T><I><K><I><Y><N><R><I><M><A><P><L><S><I><E><I><E><E><G><T><D><V><L><E><I><P><D><I><V><F><K><K><A><D><E><E><G><I><K><V><K><Y><N><T><L><E><L><I><E><L><I><K><E... | Putative transcriptional regulator.<BOP> | Q57637 |
Q8E4B4 | TARI_STRA3 | Ribitol-5-phosphate cytidylyltransferase | Streptococcus | <M><N><I><G><V><I><F><A><G><G><V><G><R><R><M><N><T><K><G><K><P><K><Q><F><L><E><V><H><G><K><P><I><I><V><H><T><I><D><I><F><Q><N><T><E><A><I><D><A><V><V><V><V><C><V><S><D><W><L><D><Y><M><N><N><L><V><E><R><F><N><L><T><K><V><K><A><V><V><A><G><G><E><T><G><Q><M><S><I><F><K><G><L><E><A><A><E><Q><L><A><T><D><D><A><V><V><L><I><H... | Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP> | Q8E4B4 |
A2T736 | ZKSC8_PANTR | Zinc finger protein 192 | Pan | <M><A><E><E><S><R><K><P><S><A><P><S><P><P><D><Q><T><P><E><E><D><L><V><I><V><K><V><E><E><D><H><G><W><D><Q><E><S><S><L><H><E><N><N><P><L><G><Q><E><V><F><R><L><R><F><R><Q><L><C><Y><Q><E><T><L><G><P><R><E><A><L><I><Q><L><R><A><L><C><H><Q><W><L><R><P><D><L><N><T><K><E><Q><I><L><E><L><L><V><L><E><Q><F><L><T><I><L><P><E><E><L... | May be involved in transcriptional regulation.<BOP> | A2T736 |
P58034 | YMGF_ECOLI | Inner membrane protein YmgF | Escherichia | <M><N><N><S><N><N><L><D><Y><F><T><L><Y><I><I><F><S><I><A><F><M><L><I><T><L><L><V><I><L><I><A><K><P><S><T><G><L><G><E><V><L><V><T><I><N><L><L><N><A><L><V><W><L><A><I><N><L><V><N><R><L><R><E><R><L><V><N><H><R><D><Q><Q> | Could be involved in cell division. May participate in the stabilization of the cell divisome under specific conditions.<BOP> | P58034 |
B3PVV3 | TRPA_RHIE6 | Tryptophan synthase alpha chain | Rhizobium | <M><T><A><R><M><D><K><R><F><A><E><L><K><A><E><G><R><P><A><L><V><T><Y><F><M><G><G><D><P><D><Y><D><T><S><L><G><I><M><K><A><L><P><E><A><G><S><D><I><I><E><L><G><M><P><F><S><D><P><M><A><D><G><P><A><I><Q><L><A><G><Q><R><A><L><K><G><G><Q><T><L><K><K><T><L><Q><L><A><A><D><F><R><K><T><D><D><A><T><P><I><V><M><M><G><Y><Y><N><P><I... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B3PVV3 |
B2VHS0 | THII_ERWT9 | tRNA 4-thiouridine synthase | Erwinia | <M><K><F><I><I><K><L><F><P><E><I><T><I><K><S><Q><S><V><R><L><R><F><I><K><I><L><T><G><N><I><R><N><V><L><K><P><Y><D><E><T><L><A><V><V><R><H><W><D><N><I><E><V><R><A><K><D><E><S><K><R><A><A><I><V><A><E><L><T><R><I><P><G><I><H><H><I><L><A><V><E><D><R><P><Y><T><D><V><H><H><I><F><E><Q><T><L><E><M><N><R><E><R><I><E><G><K><T><F... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | B2VHS0 |
E7CQW6 | UGTA1_STABO | UDP-glucosyltransferase A1 | Starmerella | <M><S><P><S><S><H><K><P><L><I><L><A><C><G><L><P><L><S><G><H><I><M><P><V><L><S><L><V><H><G><L><T><D><D><G><Y><E><A><T><V><V><T><G><R><A><F><E><Q><K><V><R><D><V><G><A><D><F><V><P><L><E><G><N><A><D><F><D><D><H><T><L><D><D><L><V><P><G><R><K><D><M><A><P><S><F><D><R><T><V><Q><D><V><E><H><M><M><V><A><T><L><P><E><Q><F><A><A><I... | Catalyzes the first glycosylation step of sophorolipid biosynthesis, the coupling of glucose to a hydroxylated fatty acid to give rise to a glucolipid . Can glycosylate all hydroxyl fatty acids generated by cytochrome P450 monooxygenases CYP52M1, CYP52N1 and CYP52E3 into their corresponding glucolipids. Main products a... | E7CQW6 |
G3Y417 | YANB_ASPNA | Yanuthone D biosynthesis cluster protein B | Aspergillus subgen. Circumdati | <M><D><R><I><D><V><H><H><H><F><I><P><P><A><Y><V><E><A><F><K><T><T><G><G><D><P><S><G><W><H><L><P><Q><W><T><P><E><S><S><L><S><L><M><D><S><H><N><T><R><T><A><I><L><S><L><T><A><P><G><T><S><I><L><A><H><S><P><G><A><S><A><T><L><A><R><E><I><N><L><Y><A><A><K><L><H><N><E><N><P><T><R><F><G><F><F><A><S><L><P><H><L><T><P><D><T><I><P... | Decarboxylase; part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria . The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase yanA . 6-MSA is then converted... | G3Y417 |
C3NGV3 | VATD_SULIN | V-ATPase subunit D | Sulfolobus | <M><S><Q><K><V><L><P><T><K><I><N><L><I><Q><F><R><R><Q><L><R><L><I><T><V><I><K><R><L><L><E><N><K><R><E><V><L><L><L><Y><L><R><T><Y><A><S><E><Y><E><K><I><Y><N><E><V><N><E><E><M><K><K><V><Y><E><S><Y><L><Q><A><V><A><S><E><G><I><S><N><I><E><E><I><A><L><S><Q><K><P><S><L><E><V><S><S><S><I><K><V><I><F><G><V><K><V><P><T><I><K><L... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | C3NGV3 |
P0DMW8 | VKT33_ACTEQ | Kunitz-type proteinase inhibitor AEPI-III | Actinia | <N><S><F><C><N><L><P><A><V><V><G><R><C><K><G><Y><F><P><R><Y><F><Y><N><T><E><A><G><K><C><Q><R><F><I><Y><G> | Dual-function toxin that inhibits both the serine protease trypsin and voltage-gated potassium channels (Kv).<BOP> | P0DMW8 |
Q9X2T1 | THIO_PSEAE | Thioredoxin | Pseudomonas | <M><S><E><H><I><V><N><V><T><D><A><S><F><E><Q><D><V><L><K><A><D><G><P><V><L><V><D><Y><W><A><E><W><C><G><P><C><K><M><I><A><P><V><L><D><E><V><A><R><D><Y><Q><G><K><L><K><V><C><K><L><N><I><D><E><N><Q><D><T><P><P><K><Y><G><V><R><G><I><P><T><L><M><L><F><K><D><G><N><V><E><A><T><K><V><G><A><L><S><K><S><Q><L><A><A><F><L><D><A><N... | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.<BOP> | Q9X2T1 |
G3FIN9 | UGTK5_MANES | Cyanohydrin UDP-glucosyltransferase UGT85K5 | Manihot | <M><G><S><L><A><S><E><I><P><P><H><A><V><L><V><P><Y><P><A><Q><G><H><V><N><P><L><M><Q><L><G><K><L><L><H><S><R><G><F><Y><I><T><F><V><N><T><E><H><N><H><R><R><L><I><R><S><R><G><Q><E><F><I><D><G><L><P><D><F><K><F><E><A><I><P><D><G><L><P><Y><T><D><R><D><A><T><Q><H><V><P><S><L><S><D><S><T><R><K><H><C><L><A><P><F><I><D><L><I><A... | UDP-glucosyltransferase catalyzing in planta synthesis of cyanogenic glucosides. Able to glucosylate acetone cyanohydrin and 2-hydroxy-2-methylbutyronitrile, forming linamarin and lotaustralin. Accepts also to some extent, a wide range of potential acceptor substrates, including simple alcohols, flavonoids, isoflavonoi... | G3FIN9 |
Q5M5E1 | TRHO_STRT2 | tRNA hydroxylation protein O | Streptococcus | <M><A><K><P><I><R><V><L><L><Y><Y><K><Y><V><P><I><E><N><A><E><Q><F><A><A><D><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><V><A><D><E><G><I><N><G><T><V><S><G><E><Y><E><T><T><Q><K><Y><M><D><Y><V><H><S><L><P><G><M><E><D><L><W><F><K><I><D><E><E><E><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><N><F><D... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | Q5M5E1 |
P84152 | TCTP_PLAKN | Translationally-controlled tumor protein homolog | Plasmodium (Plasmodium) | <M><K><V><Y><K><D><V><F><T><N><D><E><V><C><S><D><S><Y><N><Q><E><D><P><F><G><I><A><D><F><R><E><I><A><F><E><V><K><S><N><K><R><I><K><G><N><D><D><Y><G><I><A><D><N><S><E><E><A><V><D><G><M><G><A><D><V><E><Q><V><I><D><I><V><D><S><F><Q><L><T><S><T><S><L><S><K><K><E><Y><S><V><Y><I><K><N><Y><M><Q><K><I><L><K><Y><L><E><E><K><K><P... | Involved in calcium binding and microtubule stabilization.<BOP> | P84152 |
O75348 | VATG1_HUMAN | Vacuolar proton pump subunit M16 | Homo | <M><A><S><Q><S><Q><G><I><Q><Q><L><L><Q><A><E><K><R><A><A><E><K><V><S><E><A><R><K><R><K><N><R><R><L><K><Q><A><K><E><E><A><Q><A><E><I><E><Q><Y><R><L><Q><R><E><K><E><F><K><A><K><E><A><A><A><L><G><S><R><G><S><C><S><T><E><V><E><K><E><T><Q><E><K><M><T><I><L><Q><T><Y><F><R><Q><N><R><D><E><V><L><D><N><L><L><A><F><V><C><D><I><R... | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types... | O75348 |
B8DNP8 | TATA_DESVM | Sec-independent protein translocase protein TatA | Desulfovibrio | <M><F><G><I><G><I><Q><E><L><L><V><V><L><V><L><V><L><L><V><F><G><A><N><K><L><P><E><I><G><G><G><L><G><R><A><I><R><N><F><K><R><A><T><S><E><P><D><E><I><D><I><T><P><G><K><K><N><G><K><T><D><K><D><D><K><Q><A> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | B8DNP8 |
Q5M7U7 | VSTM5_RAT | V-set and transmembrane domain-containing protein 5 | Rattus | <M><R><P><P><R><C><V><G><R><T><Q><G><I><P><L><G><L><L><A><F><W><V><A><T><A><R><C><L><Q><S><Q><G><V><S><L><Y><I><P><R><S><A><I><N><A><T><V><Q><E><D><I><L><L><S><V><D><Y><I><C><H><G><V><P><T><I><E><W><E><Y><T><P><N><W><G><V><Q><K><I><V><E><W><K><P><G><T><P><A><N><V><S><Q><S><H><R><D><R><V><C><T><F><D><N><G><S><I><Q><L><F... | Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates syna... | Q5M7U7 |
Q6G547 | TRUA_BARHE | tRNA-uridine isomerase I | Bartonella | <M><P><R><F><K><L><T><L><E><Y><D><G><S><N><Y><A><G><W><Q><R><Q><A><E><L><R><T><I><Q><S><A><L><E><Q><A><L><F><H><F><S><G><Q><Q><L><T><I><T><T><A><G><R><T><D><A><G><V><H><A><T><G><Q><V><A><H><V><D><F><E><K><N><W><R><T><H><T><V><R><D><A><L><N><A><H><L><Q><K><Q><G><D><N><I><A><I><L><H><V><Q><N><V><P><D><S><F><D><A><R><F><S... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q6G547 |
A1CQN6 | YPI1_ASPCL | Type 1 phosphatases regulator ypi1 | Aspergillus subgen. Fumigati | <M><S><R><T><Q><Q><A><P><M><N><A><G><S><A><S><G><V><Q><V><A><S><P><L><S><Q><D><N><S><T><I><R><V><S><G><T><L><R><L><R><G><D><N><G><T><R><N><N><G><E><D><L><T><T><T><R><H><I><R><W><S><E><D><V><V><D><N><E><G><M><G><K><K><S><S><K><V><C><C><I><Y><H><K><D><R><P><V><G><E><S><S><S><E><S><D><D><T><D><S><S><S><D><D><C><S><D><C><D... | Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.<BOP> | A1CQN6 |
Q8NJA1 | TRI5_FUSMI | Sesquiterpene cyclase | Fusarium | <M><E><N><F><P><T><E><Y><F><L><N><T><S><V><R><L><L><E><Y><I><R><Y><R><D><S><N><Y><T><R><E><E><R><I><E><N><L><H><Y><A><Y><N><K><A><A><H><H><F><A><Q><P><R><Q><Q><Q><M><L><K><V><D><P><K><R><L><Q><A><S><L><Q><T><I><V><G><M><V><V><Y><S><W><A><K><V><S><K><E><C><M><A><D><L><S><I><H><Y><T><Y><T><L><V><L><D><D><S><S><D><D><P><H... | TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP> | Q8NJA1 |
Q8S4P9 | VCL_CORAV | Vicilin HZ.1 | Corylus | <M><L><P><K><E><D><P><E><L><K><K><C><K><H><K><C><R><D><E><R><Q><F><D><E><Q><Q><R><R><D><G><K><Q><I><C><E><E><K><A><R><E><R><Q><Q><E><E><G><N><S><S><E><E><S><Y><G><K><E><Q><E><E><N><P><Y><V><F><Q><D><E><H><F><E><S><R><V><K><T><E><E><G><R><V><Q><V><L><E><N><F><T><K><R><S><R><L><L><S><G><I><E><N><F><R><L><A><I><L><E><A><N... | Seed storage protein . Does not have superoxide dismutase (SOD) activity .<BOP> | Q8S4P9 |
P30288 | TX23A_AGEAP | Omega-agatoxin-4A | Agelenopsis | <K><K><K><C><I><A><K><D><Y><G><R><C><K><W><G><G><T><P><C><C><R><G><R><G><C><I><C><S><I><M><G><T><N><C><E><C><K><P><R><L><I><M><E><G><L><G><L><A> | Omega-agatoxins inhibit neuronal voltage-gated calcium channels. This toxin acts by modifying the gating of the high voltage activated P-type Cav2.1/CACNA1A channel. Is a potent blocker in both insect and mammalian central neurons.<BOP> | P30288 |
A5EPD3 | TYSY_BRASB | Thymidylate synthase | unclassified Bradyrhizobium | <M><H><Q><Y><H><D><L><L><E><R><I><L><S><D><G><A><E><K><H><D><R><T><G><T><G><T><L><S><V><F><G><H><Q><M><R><F><N><L><G><A><G><F><P><L><V><T><T><K><R><L><P><L><K><A><I><V><H><E><L><L><W><F><L><R><G><D><T><N><I><K><Y><L><H><D><H><G><V><T><I><W><D><E><W><A><D><A><N><G><D><L><G><P><V><Y><G><Y><Q><W><R><S><W><P><T><P><D><G><G... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | A5EPD3 |
P18737 | ZG8_XENLA | Gastrula zinc finger protein XlCGF8.2DB | Xenopus | <T><G><E><K><P><F><T><C><K><E><C><G><K><G><F><T><Q><K><R><N><L><A><S><H><M><T><I><H><T><G><E><K><P><F><S><C><T><E><C><G><K><G><F><T><Q><K><R><N><L><A><S><H><L><T><I><H><T><G><E><K><P><F><P><C><T><E><C><G><K><G><F><T><Q><K><S><N><L><V><S><H><M><K><I><H><T><G><E><K><P><F><T><C><T><E><C><G><K><E><F><A><H><K><H><R><L><L><G... | May be involved in transcriptional regulation.<BOP> | P18737 |
Q3B151 | TAL_CHLL3 | Probable transaldolase | Pelodictyon | <M><K><F><F><I><D><T><A><N><L><D><E><I><R><A><A><E><S><L><G><V><L><D><G><V><T><T><N><P><S><L><I><A><K><I><V><E><D><P><A><S><F><T><R><K><D><F><M><D><H><I><K><R><I><C><E><I><V><D><G><P><V><N><A><E><V><T><T><L><D><A><A><S><M><V><R><E><G><E><E><L><A><A><I><H><N><N><V><V><V><K><C><P><L><T><I><D><G><L><K><A><I><R><S><L><S><E... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q3B151 |
B4T5K4 | YQGF_SALNS | Putative pre-16S rRNA nuclease | Salmonella | <M><S><G><T><L><L><A><F><D><F><G><T><K><S><I><G><V><A><I><G><Q><R><I><T><G><T><A><R><P><L><P><A><I><K><A><Q><D><G><T><P><D><W><T><L><I><E><R><L><L><K><E><W><Q><P><D><E><I><I><V><G><L><P><L><N><M><D><G><T><E><Q><P><L><T><A><R><A><R><K><F><A><N><R><I><H><G><R><F><G><V><T><V><T><L><H><D><E><R><L><S><T><V><E><A><R><S><G><L... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | B4T5K4 |
Q60369 | TSAC_METJA | tRNA threonylcarbamoyladenosine biosynthesis protein MJ0062 | Methanocaldococcus | <M><G><L><K><N><K><I><I><K><I><Y><E><L><N><E><E><E><R><K><K><V><L><E><F><L><K><K><E><I><L><N><G><K><I><V><I><C><G><T><D><T><L><Y><G><I><S><A><N><A><L><N><E><K><A><V><R><K><V><Y><N><I><K><R><R><E><F><N><K><P><L><S><I><C><V><R><D><K><N><E><I><E><K><Y><A><Y><V><N><D><L><A><K><K><I><I><D><K><F><L><P><G><P><L><T><I><I><L><K... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP> | Q60369 |
Q9BVG3 | TRI62_HUMAN | Tripartite motif-containing protein 62 | Homo | <M><A><C><S><L><K><D><E><L><L><C><S><I><C><L><S><I><Y><Q><D><P><V><S><L><G><C><E><H><Y><F><C><R><R><C><I><T><E><H><W><V><R><Q><E><A><Q><G><A><R><D><C><P><E><C><R><R><T><F><A><E><P><A><L><A><P><S><L><K><L><A><N><I><V><E><R><Y><S><S><F><P><L><D><A><I><L><N><A><R><R><A><A><R><P><C><Q><A><H><D><K><V><K><L><F><C><L><T><D><R... | E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways . E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating e... | Q9BVG3 |
A7NRW4 | YBEY_ROSCS | Endoribonuclease YbeY | Roseiflexus | <M><D><D><A><E><I><L><V><D><V><Q><V><V><P><Q><Y><A><A><V><V><D><A><T><L><V><E><R><A><V><A><Q><T><L><R><T><D><D><V><A><G><P><V><E><I><S><I><L><I><T><D><D><A><D><V><H><R><L><N><Q><T><Y><R><G><V><D><A><P><T><D><V><L><S><F><A><E><D><D><D><H><S><F><V><R><P><P><D><A><P><R><Y><L><G><D><I><A><I><S><W><D><R><V><V><A><Q><A><A><E... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | A7NRW4 |
A9RHX1 | THI41_PHYPA | Thiazole biosynthetic enzyme 1 | Physcomitrium | <M><S><I><S><A><A><G><V><A><T><G><L><G><A><N><V><E><L><K><S><N><V><G><S><S><S><S><S><V><A><G><V><R><L><F><T><S><R><K><A><Q><L><R><R><C><A><A><P><A><T><S><A><S><L><Y><S><D><A><N><Y><D><L><N><N><Y><K><F><A><P><I><K><E><S><I><V><A><R><E><M><T><R><R><Y><M><T><D><M><I><T><H><A><D><T><D><V><V><V><V><G><A><G><S><A><G><L><S><C... | Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue o... | A9RHX1 |
B3QMD7 | THIG_CHLP8 | Thiazole synthase | Chlorobaculum | <M><N><A><L><R><L><G><S><Y><T><F><S><S><R><L><I><L><G><T><G><K><F><S><S><V><S><A><M><I><E><A><V><R><A><S><G><S><Q><L><V><T><V><A><L><R><R><F><N><R><E><Q><A><E><D><D><L><F><G><P><L><S><E><I><E><G><L><T><L><M><P><N><T><S><G><A><A><T><A><K><E><A><V><K><A><A><H><I><S><R><E><L><S><G><S><P><F><I><K><V><E><I><H><P><N><P><H><H... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | B3QMD7 |
Q97JI7 | YBEY_CLOAB | Endoribonuclease YbeY | Clostridium | <M><I><Y><I><D><N><R><Q><N><S><I><T><V><D><E><N><L><Q><N><T><I><R><E><V><I><D><Y><A><L><K><E><E><G><M><K><I><S><Y><E><V><S><V><I><F><V><D><N><E><T><I><R><E><I><N><R><E><N><R><E><V><D><K><V><T><D><V><L><S><F><P><M><L><E><Y><G><E><G><K><V><F><K><D><I><Y><E><E><C><D><F><E><D><E><Y><F><D><E><G><N><L><V><L><G><D><I><A><L><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q97JI7 |
Q8BWC0 | TPC2_MOUSE | Voltage-dependent calcium channel protein TPC2 | Mus | <M><A><A><E><E><Q><P><L><L><G><R><D><R><G><S><G><Q><V><H><S><G><A><A><A><D><Q><E><L><C><I><D><Q><A><V><V><F><I><E><D><A><I><K><Y><R><S><I><Y><H><R><M><D><A><G><S><L><W><L><Y><R><W><Y><Y><S><N><V><C><Q><R><V><L><G><F><I><I><F><L><I><L><I><L><A><F><V><E><V><P><S><S><F><T><K><T><A><D><V><R><Y><R><S><Q><P><W><Q><P><P><C><G... | (Microbial infection) During Ebola virus (EBOV) infection, controls the movement of endosomes containing virus particles and is required by EBOV to escape from the endosomal network into the cell cytoplasm.<BOP> | Q8BWC0 |
Q1QEI9 | UBIG_PSYCK | 3-demethylubiquinone 3-O-methyltransferase | Psychrobacter | <M><A><D><D><T><I><N><A><I><N><V><D><P><S><E><V><E><K><F><N><K><L><A><G><E><W><W><N><K><T><G><A><F><A><T><L><H><E><I><N><P><L><R><L><N><W><I><E><E><N><V><K><R><G><Y><V><S><A><D><S><Q><K><T><A><E><M><G><L><A><G><K><K><V><L><D><V><G><C><G><G><G><I><L><S><E><S><M><A><R><R><G><A><D><V><T><G><I><D><L><G><T><E><N><L><K><A><A... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q1QEI9 |
P04652 | TSHB_RAT | Thyrotropin beta chain | Rattus | <M><N><A><V><V><L><F><S><V><L><F><A><L><A><C><G><Q><V><S><S><F><C><I><P><T><E><Y><M><M><Y><V><D><R><R><E><C><A><Y><C><L><T><I><N><T><T><I><C><A><G><Y><C><M><T><R><D><I><N><G><K><L><F><L><P><K><Y><A><L><S><Q><D><V><C><T><Y><R><D><F><T><Y><R><T><V><E><I><P><G><C><P><H><H><V><A><P><Y><F><S><Y><P><V><A><L><S><C><K><C><G><K... | Indispensable for the control of thyroid structure and metabolism.<BOP> | P04652 |
B8DH80 | TMCAL_LISMH | tRNA(Met) cytidine acetate ligase | Listeria | <M><K><A><T><G><I><V><V><E><Y><N><P><F><H><N><G><H><K><L><H><L><N><K><A><R><E><L><T><Q><A><D><V><V><I><A><V><M><S><G><S><F><V><Q><R><G><E><P><A><I><I><P><K><W><E><R><A><K><M><A><L><A><A><G><V><D><M><V><I><E><L><P><V><S><F><A><T><Q><H><A><T><I><F><A><E><E><A><V><R><I><L><D><A><I><H><V><D><T><L><F><F><G><S><E><H><G><V><A... | Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.<BOP> | B8DH80 |
Q9UZQ5 | THIE_PYRAB | Thiamine-phosphate pyrophosphorylase | Pyrococcus | <M><G><F><R><E><K><L><K><L><Y><V><I><T><D><R><R><L><K><P><E><V><K><S><V><R><Q><A><L><E><G><G><A><T><S><I><Q><L><R><I><K><D><A><S><T><K><E><M><Y><E><V><G><K><E><I><R><R><L><T><Q><E><Y><D><A><L><F><F><V><D><D><R><I><D><V><A><L><A><V><N><A><D><G><V><Q><L><G><P><E><D><M><P><I><E><V><A><R><E><I><A><P><N><L><I><I><G><A><S><V... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q9UZQ5 |
Q8KZ93 | TRPA_BACNA | Tryptophan synthase alpha chain | Bacillus | <M><F><K><L><D><L><Q><P><T><E><K><L><F><I><P><F><I><T><A><G><D><P><V><P><E><V><S><I><E><L><A><K><S><L><Q><K><A><G><A><T><A><L><E><L><G><V><A><Y><S><D><P><L><A><D><G><P><V><I><Q><R><A><S><K><R><A><L><D><Q><G><M><N><I><V><K><A><I><E><L><G><G><E><M><K><K><N><G><V><N><I><P><I><I><L><F><T><Y><Y><N><P><V><L><Q><L><N><K><E><Y... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q8KZ93 |
O15178 | TBXT_HUMAN | Protein T | Homo | <M><S><S><P><G><T><E><S><A><G><K><S><L><Q><Y><R><V><D><H><L><L><S><A><V><E><N><E><L><Q><A><G><S><E><K><G><D><P><T><E><R><E><L><R><V><G><L><E><E><S><E><L><W><L><R><F><K><E><L><T><N><E><M><I><V><T><K><N><G><R><R><M><F><P><V><L><K><V><N><V><S><G><L><D><P><N><A><M><Y><S><F><L><L><D><F><V><A><A><D><N><H><R><W><K><Y><V><N><G... | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site.<BOP> | O15178 |
Q7NG92 | UPPP_GLOVI | Undecaprenyl pyrophosphate phosphatase | Gloeobacter | <M><Q><Q><Q><I><G><I><F><E><A><I><V><L><G><F><V><Q><G><I><T><E><Y><F><P><I><S><S><T><A><H><L><R><V><V><P><A><L><L><G><W><A><D><P><G><T><A><Y><S><A><V><I><Q><L><G><S><L><L><A><V><L><T><Y><F><Y><K><D><L><V><E><I><L><S><G><T><V><R><A><L><R><T><G><D><T><Q><S><R><E><V><R><L><F><W><G><I><I><L><G><T><I><P><I><V><I><A><G><L><A... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q7NG92 |
Q5L2C9 | Y616_GEOKA | Putative metal-dependent hydrolase GK0616 | Geobacillus thermoleovorans group | <M><A><T><V><D><P><I><R><Y><P><I><G><T><F><Q><A><P><Q><Q><F><E><A><G><E><V><Q><E><W><I><A><A><I><R><G><L><P><S><D><L><R><T><A><V><S><G><L><N><D><E><Q><L><N><T><P><Y><R><E><G><G><W><T><V><A><Q><V><V><H><H><L><A><D><A><S><M><N><A><F><L><R><T><K><W><G><V><T><E><D><G><P><T><V><K><P><F><A><E><S><E><W><A><K><T><A><D><A><C><L... | Possible metal-dependent hydrolase.<BOP> | Q5L2C9 |
B4U545 | TRUA_STREM | tRNA-uridine isomerase I | Streptococcus | <M><T><R><Y><K><A><I><I><S><Y><D><G><T><L><F><S><G><F><Q><R><Q><S><Q><A><R><T><V><Q><E><E><I><E><K><T><L><Q><K><L><T><G><G><Q><G><I><Q><I><H><G><A><G><I><T><D><A><G><V><H><A><Y><G><Q><V><I><H><F><D><L><E><Q><K><R><D><P><E><K><L><R><F><A><L><D><T><Q><T><P><D><D><I><D><V><I><S><L><E><I><A><A><D><D><F><H><A><R><Y><H><K><H... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | B4U545 |
B7GXE2 | UPPP_ACIB3 | Undecaprenyl pyrophosphate phosphatase | Acinetobacter calcoaceticus/baumannii complex | <M><E><N><F><E><V><I><K><A><L><F><L><G><F><V><E><G><L><T><E><F><L><P><I><S><S><T><G><H><L><I><L><F><G><H><I><I><D><F><H><S><D><G><G><R><V><F><E><V><V><I><Q><L><G><A><I><L><A><V><C><W><L><Y><R><Q><K><I><I><N><L><I><K><G><F><F><S><G><D><V><E><S><R><H><F><A><I><S><V><L><I><A><F><S><P><A><V><I><I><G><V><L><A><V><D><F><I><K... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | B7GXE2 |
B7KUV9 | TRPD_METC4 | Anthranilate phosphoribosyltransferase | Methylorubrum | <M><D><A><F><K><T><H><L><A><I><V><A><S><G><A><P><L><S><R><E><Q><A><R><A><A><F><D><D><L><L><S><G><E><V><T><P><I><Q><A><G><A><F><L><T><A><L><S><V><R><G><E><S><E><D><E><I><V><G><A><V><S><A><M><R><A><R><M><L><P><V><A><A><P><E><G><A><I><D><I><V><G><T><G><G><D><H><S><G><S><Y><N><V><S><T><L><A><A><I><L><T><A><A><C><G><V><P><V... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | B7KUV9 |
Q93GB7 | TPIS_LACDL | Triose-phosphate isomerase | Lactobacillus | <M><S><R><T><P><I><I><A><G><N><W><K><L><N><M><N><P><K><E><T><V><E><F><V><N><A><V><K><D><Q><L><P><D><P><S><K><V><E><S><V><I><C><A><P><A><V><D><L><D><A><L><L><K><A><A><E><G><S><N><L><H><V><G><A><E><N><C><Y><W><E><N><S><G><A><F><T><G><E><T><S><P><A><V><L><K><E><M><G><V><Q><Y><V><I><I><G><H><S><E><R><R><D><Y><F><H><E><T><D... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q93GB7 |
Q8NIC1 | TRI5_FUSCE | Sesquiterpene cyclase | Fusarium | <M><E><N><F><P><T><E><Y><F><L><N><T><S><V><R><L><L><E><Y><I><R><Y><R><D><S><N><Y><T><R><E><E><R><I><E><N><L><H><Y><A><Y><N><K><A><A><H><H><F><A><Q><P><R><Q><Q><K><M><L><K><V><D><P><K><R><L><Q><A><S><L><Q><T><I><V><G><M><V><V><Y><S><W><A><K><V><S><K><E><C><M><A><D><L><S><I><H><Y><T><Y><T><L><V><L><D><D><S><S><D><D><P><H... | TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP> | Q8NIC1 |
P60979 | TX13_KUKHI | Toxin DW13.3 | Kukulcania | <A><E><C><L><M><I><G><D><T><S><C><V><P><R><L><G><R><R><C><C><Y><G><A><W><C><Y><C><D><Q><Q><L><S><C><R><R><V><G><R><K><R><E><C><G><W><V><E><V><N><C><K><C><G><W><S><W><S><Q><R><I><D><D><W><R><A><D><Y><S><C><K><C><P><E><D><Q> | Potently blocks vertebrate calcium channels Cav1 and Cav2. Is the most active on Cav2.2/CACNA1B (from HEK) (IC(50)=2.3 nM), followed by Cav2.1/CACNA1A (IC(50)=4.3 nM), Cav2.2/CACNA1B (from oocyte) (IC(50)=14.4 nM), Cav1.2/CACNA1C (IC(50)=26.8 nM), and Cav2.3/CACNA1E (IC(50)=96.4 nM).<BOP> | P60979 |
Q1QE85 | TSAD_PSYCK | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Psychrobacter | <M><K><V><L><G><L><E><T><S><C><D><E><T><G><L><A><I><F><D><S><E><Q><V><T><S><D><N><K><G><L><L><G><Q><V><L><Y><S><Q><I><E><L><H><A><L><Y><G><G><V><V><P><E><L><A><S><R><D><H><I><R><K><L><V><P><L><F><N><E><L><L><Q><Q><C><N><I><T><K><D><E><I><D><A><V><A><Y><T><K><G><P><G><L><I><G><A><L><M><T><G><A><L><F><G><R><S><L><A><Y><G... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q1QE85 |
A7WNV7 | TP1A_LITPA | Temporin-1PLa | Lithobates | <M><F><T><S><K><K><S><L><L><L><L><F><F><L><G><T><I><N><L><S><L><C><E><E><E><R><D><A><D><E><E><E><R><R><D><D><P><D><E><M><N><V><E><V><E><K><R><F><L><P><L><V><G><K><I><L><S><G><L><I><G><K> | Antimicrobial activity against the Gram-positive bacterium S.aureus.<BOP> | A7WNV7 |
Q98QQ2 | TMCAL_MYCPU | tRNA(Met) cytidine acetate ligase | Mycoplasmopsis | <M><A><I><A><I><I><A><E><Y><N><P><F><H><N><G><H><I><Y><Q><I><N><Y><V><K><E><K><F><P><G><E><K><I><H><I><I><L><S><G><N><Y><V><Q><R><G><E><I><A><I><A><S><F><E><K><R><K><K><I><A><L><E><Y><G><A><D><Y><V><H><E><L><E><F><E><Y><A><S><Q><A><A><H><I><F><A><K><G><A><L><A><K><I><N><S><L><Q><I><D><K><L><I><F><G><S><E><T><N><D><I><N... | Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.<BOP> | Q98QQ2 |
C6AN26 | TORD_AGGAN | Chaperone protein TorD | Aggregatibacter | <M><L><H><H><N><Q><M><V><L><M><G><L><L><N><M><L><K><I><S><I><Q><E><R><Q><F><V><Y><S><W><I><C><S><L><L><S><K><E><L><T><Q><D><Q><L><A><H><Y><Q><R><G><D><F><D><S><L><F><A><F><L><K><E><L><G><F><T><E><Q><T><E><Q><L><I><A><T><L><R><P><M><E><F><Q><Q><L><E><L><A><A><D><F><A><H><T><F><L><L><E><G><N><I><S><A><I><P><Y><M><S><A><Y... | Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP> | C6AN26 |
A4Y5U9 | TOLB_SHEPC | Tol-Pal system protein TolB | Shewanella | <M><K><I><L><A><K><W><L><A><L><A><V><L><L><C><T><T><P><T><K><A><A><L><D><I><V><I><T><E><G><I><D><A><A><R><P><I><A><V><M><P><F><V><W><Q><G><T><G><A><P><P><Q><A><I><A><D><V><V><M><S><D><L><V><R><S><G><T><F><K><P><L><D><E><L><G><L><P><Q><R><N><I><G><A><V><A><Q><F><Q><A><S><A><W><G><S><V><G><A><E><A><L><V><L><G><S><V><K><P... | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP> | A4Y5U9 |
Q4QLR0 | YIDC_HAEI8 | Membrane protein YidC | Haemophilus | <M><D><S><R><R><S><L><L><V><L><A><L><I><F><I><S><F><L><V><Y><Q><Q><W><Q><L><D><K><N><P><P><V><Q><T><E><Q><T><T><S><I><T><A><T><S><D><V><P><A><S><S><P><S><N><S><Q><A><I><A><D><S><Q><T><R><G><R><I><I><T><L><E><N><D><V><F><R><L><K><I><D><T><L><G><G><D><V><I><S><S><E><L><L><K><Y><D><A><E><L><D><S><K><T><P><F><E><L><L><K><D... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | Q4QLR0 |
C3MCT9 | UPPP_SINFN | Undecaprenyl pyrophosphate phosphatase | Sinorhizobium | <M><A><D><Q><S><I><I><S><A><L><V><L><G><L><I><E><G><L><T><E><F><I><P><V><S><S><T><A><H><V><L><L><A><G><H><F><L><G><F><K><S><P><G><N><T><F><A><V><L><I><Q><L><G><A><I><L><A><I><L><L><V><Y><F><Q><K><L><L><S><I><A><L><A><L><P><T><S><V><K><A><R><R><F><V><F><S><V><L><I><A><F><L><P><A><A><L><I><G><A><A><A><H><G><F><I><K><A><V... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | C3MCT9 |
P81660 | TNNC2_ANGAN | Troponin C, skeletal muscle | Anguilla | <P><T><D><A><Q><T><D><A><R><S><F><L><S><E><E><M><I><A><E><F><K><A><A><F><D><M><F><D><T><D><G><G><G><D><I><S><T><K><E><L><G><T><V><M><R><M><L><G><Q><N><P><T><R><E><E><L><D><A><I><I><E><E><V><D><E><D><G><S><G><T><I><D><F><E><E><F><L><V><M><M><V><R><Q><L><K><E><D><Q><A><G><K><S><E><E><E><L><A><E><F><F><R><V><F><D><K><N><G... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding EF-hand for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P81660 |
Q5PK87 | THIG_SALPA | Thiazole synthase | Salmonella | <M><L><R><I><A><D><K><T><F><D><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><A><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><A><P><L><I><E><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><Q><L><A><R><E><A><L><G><T><H><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | Q5PK87 |
O34522 | TRMB_BACSU | tRNA(m7G46)-methyltransferase | Bacillus | <M><R><M><R><H><K><P><W><A><D><D><F><L><A><E><N><A><D><I><A><I><S><N><P><A><D><Y><K><G><K><W><N><T><V><F><G><N><D><N><P><I><H><I><E><V><G><T><G><K><G><Q><F><I><S><G><M><A><K><Q><N><P><D><I><N><Y><I><G><I><E><L><F><K><S><V><I><V><T><A><V><Q><K><V><K><D><S><E><A><Q><N><V><K><L><L><N><I><D><A><D><T><L><T><D><V><F><E><P><G... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | O34522 |
Q9D806 | VSTM5_MOUSE | V-set and transmembrane domain-containing protein 5 | Mus | <M><R><P><L><R><C><G><E><R><T><Q><G><I><P><L><G><L><L><A><F><W><V><T><A><A><R><C><L><Q><S><Q><G><V><S><L><Y><I><P><Q><S><A><I><N><A><T><V><Q><Q><D><I><L><L><S><V><D><Y><I><C><H><G><V><P><T><I><E><W><K><Y><T><P><N><W><G><V><Q><R><I><V><E><W><K><P><G><T><P><A><N><V><S><Q><S><H><R><D><R><V><C><T><F><D><N><G><S><I><Q><L><F... | Cell adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and complexity of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions including dendritic filopodia. In synaptogenesis, regulates syna... | Q9D806 |
Q1LSM0 | TSAD_BAUCH | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Candidatus Baumannia | <M><R><V><L><G><I><E><T><S><C><D><D><T><G><V><A><I><Y><D><D><Q><H><G><L><L><T><N><Q><I><Y><S><Q><A><K><I><H><A><N><Y><G><G><V><V><P><E><L><A><S><R><D><H><L><R><K><I><V><P><L><I><Q><A><A><L><S><E><A><R><L><Q><A><K><N><I><D><G><V><A><Y><T><A><G><P><G><L><I><S><S><L><M><V><G><A><T><V><G><C><A><L><A><Y><A><W><K><V><P><N><I... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q1LSM0 |
B7GW49 | XPT_ACIB3 | Xanthine phosphoribosyltransferase | Acinetobacter calcoaceticus/baumannii complex | <M><H><A><L><E><Q><K><I><L><T><E><G><I><V><L><S><D><Q><V><L><K><V><D><A><F><L><N><H><Q><I><D><P><V><L><M><Q><Q><I><G><K><E><F><A><A><R><F><K><D><A><G><I><T><K><I><I><T><I><E><A><S><G><I><A><P><A><I><M><A><G><L><E><L><G><V><P><V><I><F><A><R><K><Y><Q><S><L><T><L><K><D><D><L><Y><R><A><K><V><F><S><F><T><K><Q><T><E><S><T><I... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | B7GW49 |
Q92BX6 | YIDC1_LISIN | Membrane protein YidC 1 | Listeria | <M><K><K><K><N><I><I><L><I><S><V><L><L><G><A><L><L><L><I><T><G><C><S><M><D><P><S><Q><N><T><D><G><F><F><S><T><Y><L><I><Q><P><F><T><S><F><I><M><F><V><A><K><F><V><G><G><N><Y><G><I><A><I><I><I><T><T><L><L><I><R><A><L><I><M><P><L><N><L><R><T><A><K><A><Q><M><G><M><Q><S><K><M><A><V><A><K><P><E><I><D><E><I><Q><A><R><L><K><R><A... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.<BOP> | Q92BX6 |
Q6LN28 | UPPS_PHOPR | Undecaprenyl pyrophosphate synthase | Photobacterium | <M><A><E><R><T><I><E><T><E><L><S><A><E><C><L><P><K><H><V><A><V><I><M><D><G><N><G><R><W><A><K><A><K><G><K><A><R><V><F><G><H><K><A><G><V><E><A><V><R><K><S><V><T><T><A><N><R><L><G><V><K><V><L><T><L><F><A><F><S><S><E><N><W><R><R><P><E><D><E><V><S><L><L><M><E><L><F><M><T><V><L><T><R><E><V><K><R><L><H><K><N><N><I><Q><L><R><I... | Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide c... | Q6LN28 |
A0ALT4 | TRUA_LISW6 | tRNA-uridine isomerase I | Listeria | <M><T><R><Y><K><A><I><I><S><Y><D><G><S><G><F><Y><G><Y><Q><I><Q><P><N><A><R><T><V><Q><A><E><I><E><K><A><L><K><K><M><H><K><G><K><N><V><R><I><T><A><S><G><R><T><D><T><G><V><H><A><K><G><Q><V><I><H><F><D><S><D><L><D><I><T><A><D><K><F><Q><K><A><L><Q><V><M><T><P><F><D><I><S><F><L><T><V><D><E><A><P><A><D><F><H><A><R><F><G><T><V... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | A0ALT4 |
Q2YJ75 | VIRB5_BRUA2 | Type IV secretion system protein virB5 | Brucella | <M><K><K><I><I><L><S><F><A><F><A><L><T><V><T><S><T><A><H><A><Q><L><P><V><T><D><A><G><S><I><A><Q><N><L><A><N><H><L><E><Q><M><V><K><F><A><Q><Q><I><E><Q><L><K><Q><Q><F><E><Q><Q><K><M><Q><F><D><A><L><T><G><N><R><G><L><G><D><I><L><R><D><P><T><L><R><S><Y><L><P><H><N><W><R><D><L><Y><E><A><V><M><S><G><G><Y><L><A><A><A><G><E><T... | The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.<BOP> | Q2YJ75 |
G3Y424 | YANF_ASPNA | Yanuthone D biosynthesis cluster protein F | Aspergillus subgen. Circumdati | <M><S><S><S><A><E><C><R><P><I><G><W><G><G><W><G><P><D><P><N><T><S><P><T><R><A><A><I><K><W><F><A><D><P><R><S><L><H><H><Q><Q><C><A><C><G><L><W><N><A><R><R><A><M><Q><W><V><I><P><A><P><P><R><I><W><I><D><D><Q><P><R><M><V><K><L><A><Y><I><L><G><A><V><T><V><F><L><T><S><G><N><A><A><D><V><S><P><T><S><S><V><A><A><S><T><T><P><S><A... | FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria . The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase yanA . 6-MSA is ... | G3Y424 |
Q3KQV3 | ZN792_HUMAN | Zinc finger protein 792 | Homo | <M><A><A><A><A><L><R><D><P><A><Q><G><C><V><T><F><E><D><V><T><I><Y><F><S><Q><E><E><W><V><L><L><D><E><A><Q><R><L><L><Y><C><D><V><M><L><E><N><F><A><L><I><A><S><L><G><L><I><S><F><R><S><H><I><V><S><Q><L><E><M><G><K><E><P><W><V><P><D><S><V><D><M><T><S><A><M><A><R><G><A><Y><G><R><P><G><S><D><F><C><H><G><T><E><G><K><D><L><P><S... | May be involved in transcriptional regulation.<BOP> | Q3KQV3 |
Q9KN48 | VASH_VIBCH | Transcriptional regulator VasH | Vibrio | <M><S><Q><W><L><A><F><A><T><Q><L><V><G><V><R><K><S><H><Q><L><A><L><Q><F><V><D><L><L><T><Q><G><L><D><L><S><D><S><L><L><L><L><P><S><S><D><G><R><L><L><V><P><H><D><P><Q><R><Q><F><A><W><S><V><T><D><F><D><V><P><F><A><H><V><L><Q><S><S><N><A><M><H><L><T><A><E><E><L><V><F><W><Q><S><N><R><T><F><S><Q><L><T><S><R><V><G><M><F><D><S... | Transcriptional regulator of the type VI secretion system.<BOP> | Q9KN48 |
B6J3P6 | UBIE_COXB2 | Demethylmenaquinone methyltransferase | Coxiella | <M><N><E><T><E><K><S><T><H><F><G><Y><Q><T><V><P><T><D><Q><K><T><D><K><V><K><H><V><F><E><S><V><A><A><K><Y><D><L><M><N><D><L><M><S><L><G><I><H><R><W><W><K><D><F><A><I><T><Q><C><R><L><R><T><G><Q><R><I><L><D><L><A><G><G><T><G><D><L><A><K><R><I><S><P><L><V><G><D><E><G><E><V><V><I><A><D><I><N><A><A><M><L><N><V><G><R><R><R><L... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | B6J3P6 |
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