accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q3ZC10
SMD1_BOVIN
snRNP core protein D1
Bos
<M><K><L><V><R><F><L><M><K><L><S><H><E><T><V><T><I><E><L><K><N><G><T><Q><V><H><G><T><I><T><G><V><D><V><S><M><N><T><H><L><K><A><V><K><M><T><L><K><N><R><E><P><V><Q><L><E><T><L><S><I><R><G><N><N><I><R><Y><F><I><L><P><D><S><L><P><L><D><T><L><L><V><D><V><E><P><K><V><K><S><K><K><R><E><A><V><A><G><R><G><R><G><R><G><R><G><R><G...
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome...
Q3ZC10
C1DNF9
RNPA_AZOVD
Protein C5
Azotobacter
<M><V><S><R><D><F><G><R><E><K><R><L><L><I><P><R><Q><F><K><A><V><F><D><S><P><T><A><K><V><P><G><K><H><V><L><L><L><A><R><P><N><A><L><D><H><P><R><L><G><L><V><I><G><K><K><S><V><K><L><S><V><G><R><N><R><L><K><R><L><I><R><E><S><F><R><L><N><Q><D><S><L><A><G><W><D><I><V><V><V><A><R><K><G><L><G><E><L><E><N><T><E><V><T><Q><Q><F><G...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
C1DNF9
Q9C6L5
KCS5_ARATH
Very long-chain fatty acid condensing enzyme 5
Arabidopsis
<M><S><D><F><S><S><S><V><K><L><K><Y><V><K><L><G><Y><Q><Y><L><I><N><N><F><L><T><L><L><L><I><P><V><I><A><T><V><A><I><E><L><L><R><M><G><P><E><E><I><L><S><V><L><N><S><L><H><F><E><L><L><H><I><L><C><S><S><F><L><I><I><F><V><S><T><V><Y><F><M><S><K><P><R><T><V><Y><L><V><D><Y><S><C><Y><K><P><P><V><T><C><R><V><P><F><S><S><F><M><E...
Mediates mostly the synthesis of VLCFAs from 26 to 30 carbons in length (e.g. C20:1, C26, C28, C30).<BOP>
Q9C6L5
A3PNF6
TRUB_CERS1
tRNA-uridine isomerase
Cereibacter
<M><G><R><T><R><K><G><R><A><I><S><G><W><L><V><V><D><K><P><A><G><M><T><S><T><A><V><V><N><K><V><R><W><A><L><E><A><Q><K><A><G><H><A><G><T><L><D><P><D><A><T><G><V><L><A><V><A><L><G><E><A><T><K><T><V><P><Y><I><T><D><A><L><K><C><Y><R><F><M><V><R><L><G><L><S><T><R><T><D><D><A><S><G><E><V><I><A><T><S><E><A><R><P><T><D><A><E><I...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
A3PNF6
Q4QLH8
DEOC_HAEI8
Phosphodeoxyriboaldolase
Haemophilus
<M><T><S><N><Q><L><A><Q><Y><I><D><H><T><A><L><T><A><E><K><N><E><Q><D><I><S><T><L><C><N><E><A><I><E><H><G><F><Y><S><V><C><I><N><S><G><Y><I><P><L><A><K><E><K><L><A><G><S><N><V><K><I><C><T><V><V><G><F><P><L><G><A><N><L><T><S><V><K><A><F><E><T><Q><E><A><I><K><A><G><A><N><E><I><D><M><V><I><N><V><G><W><I><K><S><Q><K><W><D><A...
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP>
Q4QLH8
A9IJ97
MNME_BORPD
tRNA modification GTPase MnmE
Bordetella
<M><A><S><S><T><H><V><P><I><A><A><I><A><T><A><P><G><R><G><G><I><G><V><V><R><I><S><G><P><D><L><S><A><L><A><R><R><L><F><G><R><E><L><T><P><R><H><A><H><Y><L><P><F><T><A><E><T><G><E><H><L><D><E><G><I><A><L><Y><F><R><A><P><Q><S><Y><T><G><E><D><V><L><E><L><Q><G><H><G><G><P><A><V><L><R><R><I><L><E><R><C><L><Q><A><G><A><D><L><G...
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
A9IJ97
Q8Z9J5
RLUA_SALTI
tRNA pseudouridine(32) synthase
Salmonella
<M><G><M><E><N><Y><N><P><P><Q><E><P><W><L><V><I><L><Y><Q><D><E><H><I><M><V><V><N><K><P><S><G><L><L><S><V><P><G><R><L><E><A><H><K><D><S><I><M><T><R><I><Q><R><D><Y><P><Q><A><E><S><V><H><R><L><D><M><A><T><S><G><V><I><V><V><A><L><T><K><A><A><E><R><E><L><K><R><Q><F><R><E><R><E><P><K><K><Q><Y><V><A><R><V><W><G><H><P><S><P><A...
Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs.<BOP>
Q8Z9J5
Q1MPK3
FABZ_LAWIP
Beta-hydroxyacyl-ACP dehydratase
Lawsonia
<M><S><H><P><L><P><P><N><I><Q><E><I><L><Q><L><L><P><H><R><Y><P><F><L><L><V><D><R><V><I><E><F><N><A><G><K><Y><I><K><A><Y><K><N><V><S><I><N><E><P><F><F><Q><G><H><F><P><G><F><P><V><M><P><G><V><L><I><L><E><A><M><A><Q><S><G><G><I><T><V><L><Q><S><F><P><I><N><E><L><Q><G><K><V><F><L><F><A><G><I><E><N><V><K><F><R><Q><Q><V><I><P...
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.<BOP>
Q1MPK3
Q8EGH4
EFTS_SHEON
Elongation factor Ts
Shewanella
<M><A><I><S><A><A><Q><V><K><E><L><R><E><R><T><G><A><G><M><M><D><C><K><K><A><L><E><E><T><N><G><D><M><E><L><A><I><D><N><M><R><K><S><G><A><A><K><A><A><K><K><A><G><N><I><A><A><D><G><T><I><L><I><K><N><G><E><G><F><A><V><L><L><E><V><N><C><Q><T><D><F><V><A><K><D><A><N><F><L><G><F><A><N><A><V><L><D><V><A><A><A><S><K><V><T><L><E...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
Q8EGH4
Q9AMJ9
CH10_ANASL
Chaperonin-10
unclassified Anabaena
<M><A><A><V><S><L><S><V><S><T><V><K><P><L><G><D><R><V><F><V><K><V><S><A><S><E><K><R><P><R><R><L><Y><F><P><D><T><A><K><E><K><P><Q><V><G><E><V><V><A><L><G><A><G><K><R><N><D><D><G><S><R><Q><E><L><E><V><K><V><G><D><L><L><L><Y><S><K><Y><A><G><T><D><V><K><L><G><T><E><E><Y><V><L><L><S><E><K><D><I><L><A><M><V><G>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
Q9AMJ9
P17245
EFTU_CYAPA
Elongation factor Tu, cyanelle
Cyanophora
<M><A><R><Q><K><F><D><G><N><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><T><A><L><A><S><Q><G><K><G><K><A><R><K><Y><D><E><I><D><A><A><P><E><E><K><A><R><G><I><T><I><N><T><A><H><V><E><Y><E><T><E><K><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
P17245
Q94A73
Y5656_ARATH
BTB/POZ domain-containing protein At5g66560
Arabidopsis
<M><A><S><E><K><S><T><S><K><G><Q><A><W><F><C><T><T><G><L><P><S><D><I><E><I><E><V><D><D><M><T><F><H><L><H><K><F><P><L><M><S><K><S><R><K><L><H><R><L><I><T><E><Q><E><T><R><S><S><S><S><M><A><L><I><T><V><I><D><P><K><V><E><E><T><D><K><K><G><K><G><H><E><I><E><D><D><K><E><E><E><E><V><E><E><Q><E><I><E><E><N><G><Y><P><H><I><K><L...
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP>
Q94A73
P45268
Y1604_HAEIN
Putative phosphate permease HI_1604
Haemophilus
<M><E><I><I><S><Q><Y><G><S><W><L><V><W><I><T><A><V><F><G><F><F><M><A><F><G><I><G><A><N><D><V><S><N><S><M><G><T><S><V><G><S><G><T><I><T><A><K><Q><A><I><I><I><A><L><I><F><E><S><A><G><A><Y><L><A><G><G><E><V><T><Q><T><I><K><S><G><V><I><E><P><I><Q><F><V><D><T><P><D><I><L><A><L><G><M><L><S><T><L><F><A><S><G><A><W><L><F><I><A...
Potential transporter for phosphate.<BOP>
P45268
Q9LCJ2
NQRF_COLPS
NQR-1 subunit F
Colwellia
<G><G><S><C><G><Q><C><R><V><E><V><H><S><G><G><G><D><I><L><P><T><E><E><G><H><I><N><K><R><E><A><K><S><G><C><R><L><A><C><Q><V><A><V><K><Q><D><M><E><I><E><V><E><D><E><I><F><G><V><Q><Q><W><E><C><E><V><I><S><N><D><N><Q><A><T><F><I><K><E><L><K><L><Q><I><P><N><G><E><S><V><P><F><K><A><G><G><Y><I><Q><I><E><A><P><A><H><H><V><K><Y...
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway...
Q9LCJ2
A1UUD5
IF3_BARBK
Translation initiation factor IF-3
Bartonella
<M><T><P><N><Q><K><D><G><P><R><S><N><Q><E><I><R><V><P><C><I><Q><L><I><N><D><E><G><Q><N><Q><G><I><V><S><T><Q><E><A><L><A><M><A><A><N><I><G><L><D><L><V><E><I><V><P><N><A><E><P><P><V><C><K><I><V><D><L><G><K><L><K><Y><Q><N><Q><K><K><A><A><E><T><R><K><K><Q><K><I><I><E><I><K><E><I><K><L><R><P><N><V><D><V><H><D><Y><G><V><K><L...
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP>
A1UUD5
C5C0R4
NUON_BEUC1
NDH-1 subunit N
Beutenbergia
<M><N><F><V><Q><P><V><I><Q><W><A><S><L><A><P><I><L><I><V><L><G><A><A><V><L><G><V><L><I><E><A><F><A><P><R><R><V><R><R><P><V><Q><V><T><L><A><L><L><A><A><A><G><A><F><G><A><I><A><W><R><W><A><E><V><I><G><G><G><G><G><A><P><S><T><V><V><V><G><Q><L><V><E><D><G><P><A><L><A><A><Q><G><I><I><A><I><L><A><F><V><G><I><L><V><I><A><E><R...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar...
C5C0R4
Q475M4
RECA_CUPPJ
Recombinase A
Cupriavidus
<M><D><D><K><K><A><G><A><G><L><S><A><E><K><Q><K><A><L><A><A><A><L><S><Q><I><E><K><Q><F><G><K><G><S><I><M><R><M><G><D><G><E><V><E><K><D><I><Q><V><V><S><T><G><S><L><G><L><D><I><A><L><G><V><G><G><L><P><R><G><R><V><V><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><Q><V><V><A><E><M><Q><K><L><G><G><T><C><A><F><I><D><A><E><H><A...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
Q475M4
B4RSL8
SYT_ALTMD
Threonyl-tRNA synthetase
Alteromonas
<M><P><V><I><T><L><P><D><G><S><Q><R><A><F><D><N><P><V><S><V><L><D><V><A><N><D><I><G><P><G><L><A><K><A><T><I><A><G><K><V><N><G><E><L><V><D><A><V><D><M><I><D><A><D><A><Q><L><Q><I><I><T><A><K><D><E><E><G><L><E><I><L><R><H><S><C><A><H><L><L><G><H><A><I><K><Q><L><W><P><N><T><K><M><A><I><G><P><V><I><D><N><G><F><Y><Y><D><V><D...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
B4RSL8
Q698K8
VM2L4_GLOBR
Disintegrin halystatin
Gloydius
<E><D><E><A><P><K><M><C><G><V><T><Q><N><W><E><S><Y><E><P><I><K><K><A><S><Q><S><N><L><T><P><A><H><Q><R><Y><I><E><L><V><I><V><A><D><H><G><M><F><T><K><Y><N><G><D><S><D><K><I><R><E><W><V><R><Q><M><V><N><T><V><D><E><I><Y><S><Y><M><Y><I><D><V><A><L><A><G><L><E><I><W><S><N><E><D><L><I><N><V><Q><P><A><A><P><H><T><L><D><S><F><G...
Inhibits platelet aggregation induced by ADP (IC(50) is 100 nM), collagen (IC(50) is 500 nM), thrombin and epinephrin (IC(50) is 300 nM). Does not inhibit aggregation induced by ristocetin. Significantly inhibits angiogenesis both in vivo and in vitro.<BOP>
Q698K8
P32826
SCP49_ARATH
Serine carboxypeptidase-like 49
Arabidopsis
<M><E><K><L><T><F><L><S><L><L><L><H><F><V><V><F><I><A><S><T><I><P><S><S><S><F><L><L><N><D><R><T><F><E><R><S><N><L><P><S><T><R><A><E><K><L><I><R><E><L><N><L><F><P><Q><Q><D><L><N><V><I><D><V><A><D><L><P><L><T><A><A><E><G><P><G><I><V><E><R><K><F><V><F><P><N><I><L><A><D><G><G><P><T><V><D><D><L><G><H><H><A><G><Y><Y><K><L><P...
Probable carboxypeptidase.<BOP>
P32826
Q07981
FAR1_CORAP
NDPYLRF-amide
Cornu
<M><T><S><L><C><L><T><I><A><P><A><V><L><S><L><I><C><L><S><S><Y><G><W><A><E><G><D><T><T><D><N><E><Y><L><R><F><G><R><E><N><N><N><G><Y><I><R><F><G><R><N><D><P><F><L><R><F><G><K><K><S><D><P><F><L><R><F><G><K><Q><D><P><F><L><R><I><G><R><Q><D><P><F><L><R><F><G><K><Q><D><P><F><L><R><F><G><K><Q><D><P><F><L><R><I><G><K><Q><D><P...
Can function as both cardioregulatory hormones and transmitters and may regulate cardiovascular function.<BOP>
Q07981
C1D5E0
RECR_LARHH
Recombination protein RecR
Laribacter
<M><K><T><P><A><S><L><E><S><L><I><T><A><L><R><V><L><P><G><V><G><P><K><T><A><Q><R><M><A><Y><H><L><M><Q><R><D><P><G><G><A><D><R><L><A><R><A><I><D><H><A><R><S><H><L><K><H><C><A><R><C><N><T><F><S><E><T><E><L><C><V><L><C><A><D><D><Q><R><R><Q><D><V><L><C><V><V><E><M><P><A><D><A><L><M><I><E><Q><T><H><S><Y><D><G><L><Y><F><V><L...
May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP>
C1D5E0
B0S230
PFKA_FINM2
Phosphohexokinase
Finegoldia
<M><K><T><I><A><I><L><T><S><G><G><D><A><P><G><M><N><A><C><I><R><S><I><A><R><T><C><I><Y><N><G><I><R><V><M><G><I><R><S><G><Y><D><G><L><M><N><G><N><I><Y><E><M><N><V><S><S><V><A><D><I><I><H><R><G><G><T><I><L><G><S><A><R><C><P><E><F><K><T><E><E><G><Q><K><K><G><A><Q><I><L><K><D><F><G><I><D><G><L><V><V><L><G><G><D><G><S><F><K...
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.<BOP>
B0S230
P16497
KINA_BACSU
Stage II sporulation protein J
Bacillus
<M><E><Q><D><T><Q><H><V><K><P><L><Q><T><K><T><D><I><H><A><V><L><A><S><N><G><R><I><I><Y><I><S><A><N><S><K><L><H><L><G><Y><L><Q><G><E><M><I><G><S><F><L><K><T><F><L><H><E><E><D><Q><F><L><V><E><S><Y><F><Y><N><E><H><H><L><M><P><C><T><F><R><F><I><K><K><D><H><T><I><V><W><V><E><A><A><V><E><I><V><T><T><R><A><E><R><T><E><R><E><I...
Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP.<BOP>
P16497
P58393
GLGA1_RHIME
Starch [bacterial glycogen] synthase 1
Sinorhizobium
<M><N><I><L><S><V><A><S><E><V><Y><P><L><V><K><T><G><G><L><A><D><V><V><G><A><L><P><S><A><L><L><P><H><G><V><R><T><R><T><L><V><P><G><Y><P><S><V><L><K><K><L><K><K><K><K><P><V><G><R><F><D><N><L><F><G><H><P><A><T><V><L><A><A><E><V><N><G><V><D><L><L><V><L><D><Q><P><A><L><Y><A><R><D><G><G><P><Y><L><D><S><T><G><R><D><Y><P><D><N...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
P58393
Q9H3J6
MTRFR_HUMAN
Mitochondrial translation release factor in rescue
Homo
<M><S><T><V><G><L><F><H><F><P><T><P><L><T><R><I><C><P><A><P><W><G><L><R><L><W><E><K><L><T><L><L><S><P><G><I><A><V><T><P><V><Q><M><A><G><K><K><D><Y><P><A><L><L><S><L><D><E><N><E><L><E><E><Q><F><V><K><G><H><G><P><G><G><Q><A><T><N><K><T><S><N><C><V><V><L><K><H><I><P><S><G><I><V><V><K><C><H><Q><T><R><S><V><D><Q><N><R><K><L...
Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation . As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis f...
Q9H3J6
P40649
SOX13_XENLA
Transcription factor Sox-12
Xenopus
<M><D><T><I><Q><G><E><L><V><Y><C><P><A><N><E><Q><E><C><R><I><S><A><K><I><P><I><S><P><S><E><D><T><G><G><P><C><L><K><V><E><E><D><Y><E><E><V><S><L><Q><T><G><I><V><P><V><F><I><K><Q><D><Y><E><S><S><S><Q><D><A><N><D><L><C><K><P><Q><G><D><A><P><A><S><D><R><K><E><E><N><L><K><L><S><K><T><V><S><D><A><M><P><A><L><E><K><F><L><S><N...
Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3'.<BOP>
P40649
A6VGV3
RS12_METM7
30S ribosomal protein S12
Methanococcus
<M><A><G><S><K><S><P><K><G><E><F><A><G><R><K><L><L><L><K><R><R><A><S><R><W><H><H><Y><K><Y><V><N><K><A><L><S><L><K><L><K><A><D><P><L><E><G><A><P><M><G><R><G><I><V><V><E><K><V><G><L><E><A><K><Q><P><N><S><A><I><R><K><C><V><R><V><Q><L><I><K><N><G><R><Q><V><T><A><F><A><P><G><N><H><A><I><N><F><I><D><E><H><D><E><V><V><I><E><G...
With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.<BOP>
A6VGV3
P03919
NU5M_HYLLA
NADH dehydrogenase subunit 5
Hylobates
<M><A><M><Y><T><T><M><A><I><L><T><L><T><S><L><I><P><P><I><T><A><T><L><I><N><P><N><K><K><N><L><Y><P><H><Y><V><K><M><T><I><A><S><T><F><M><I><S><L><F><P><T><M><M><F><M><C><T><D><Q><E><T><I><I><S><N><W><H><W><T><A><T><Q><T><L><E><L><S><L><S><F><K><L><D><Y><F><S><M><M><F><I><P><I><A><L><F><V><T><W><S><I><M><E><F><S><L><W><Y...
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP>
P03919
Q57HL7
SRKA_SALCH
Serine/threonine-protein kinase SrkA
Salmonella
<M><N><D><N><A><F><T><F><Q><T><L><H><P><E><T><I><M><D><A><L><F><E><Q><G><I><R><V><D><S><G><L><T><P><L><N><S><Y><E><N><R><V><Y><Q><F><Q><D><E><D><R><R><R><F><V><V><K><F><Y><R><P><E><R><W><S><V><D><Q><I><R><E><E><H><Q><F><A><L><E><L><V><K><D><E><V><P><V><A><A><P><L><A><F><N><G><Q><T><L><L><A><H><Q><G><Y><H><Y><A><I><F><P...
A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.<BOP>
Q57HL7
P54799
NIFH1_METBA
Nitrogenase reductase
Methanosarcina
<M><T><R><K><I><A><F><Y><G><K><G><G><I><G><K><S><T><T><Q><Q><N><T><A><A><A><M><A><Y><Y><H><G><K><K><I><F><I><H><G><C><D><P><K><A><D><C><T><R><L><V><L><G><G><V><A><Q><T><T><I><M><D><T><L><R><E><L><G><E><D><A><V><T><A><E><N><V><I><N><T><G><F><D><G><I><K><C><V><E><S><G><G><P><E><P><G><V><G><C><A><G><R><G><V><I><T><A><I><N...
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.<BOP>
P54799
B0B9Q4
DNLJ_CHLT2
Polydeoxyribonucleotide synthase [NAD(+)]
Chlamydia
<M><G><A><V><S><R><D><D><Y><I><A><L><C><T><E><L><V><E><H><D><R><R><Y><Y><A><L><N><Q><P><T><I><S><D><Y><S><Y><D><M><K><M><R><E><L><Q><E><I><E><V><Q><H><P><E><W><K><V><S><W><S><P><T><M><Y><L><G><D><R><P><S><G><Q><F><P><V><V><P><H><S><S><P><M><L><S><I><A><N><V><Y><S><L><Q><E><L><E><E><F><F><S><R><T><E><K><L><L><G><Y><S><P...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
B0B9Q4
A0A455LLW0
ATNJ_ARTSZ
Arthripenoid biosynthesis cluster protein J
unclassified Arthrinium
<M><S><T><T><K><P><I><C><L><V><P><L><H><V><V><I><V><G><A><G><I><G><G><L><S><A><A><V><A><L><A><N><R><G><H><S><V><L><I><L><E><S><T><S><E><L><S><H><V><G><A><G><V><A><L><P><P><T><T><R><K><W><Y><E><S><E><G><V><L><Q><V><D><D><T><A><C><V><P><L><E><G><I><E><I><T><K><W><D><T><G><E><L><V><T><R><T><A><A><N><P><A><G><K><Q><T><A><I...
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids arthripenoids . The pathway begins with the HR-PKS atnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS atnG to initiate three more cycles of ex...
A0A455LLW0
Q8H6Q1
DEF1_PETHY
PhD1
Petunia
<M><A><R><S><I><C><F><F><A><V><A><I><L><A><L><M><L><F><A><A><Y><D><A><E><A><A><T><C><K><A><E><C><P><T><W><D><S><V><C><I><N><K><K><P><C><V><A><C><C><K><K><A><K><F><S><D><G><H><C><S><K><I><L><R><R><C><L><C><T><K><E><C><V><F><E><K><T><E><A><T><Q><T><E><T><F><T><K><D><V><N><T><L><A><E><A><L><L><E><A><D><M><M><V>
Plant defense peptide with antifungal activity against F.oxysporum and B.cinerea.<BOP>
Q8H6Q1
O80920
PYL4_ARATH
Regulatory components of ABA receptor 10
Arabidopsis
<M><L><A><V><H><R><P><S><S><A><V><S><D><G><D><S><V><Q><I><P><M><M><I><A><S><F><Q><K><R><F><P><S><L><S><R><D><S><T><A><A><R><F><H><T><H><E><V><G><P><N><Q><C><C><S><A><V><I><Q><E><I><S><A><P><I><S><T><V><W><S><V><V><R><R><F><D><N><P><Q><A><Y><K><H><F><L><K><S><C><S><V><I><G><G><D><G><D><N><V><G><S><L><R><Q><V><H><V><V><S...
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA . Can be activated by both (-)-ABA and (+)-ABA .<BOP>
O80920
Q046I4
XPT_LACGA
Xanthine phosphoribosyltransferase
Lactobacillus
<M><K><L><L><E><E><R><I><R><K><D><G><E><V><L><D><G><D><V><L><K><I><N><S><F><L><N><H><Q><V><D><P><E><L><M><M><Q><V><G><E><E><F><K><R><L><F><E><N><E><K><I><T><K><V><L><T><C><E><A><S><G><I><A><P><G><I><M><A><A><Y><Q><L><G><V><P><M><V><F><A><R><K><K><K><P><S><T><L><N><D><A><V><Y><W><A><D><V><F><S><Y><T><K><K><V><N><N><K><I...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
Q046I4
P13106
FER_BUMFI
Ferredoxin
Bumilleriopsis
<E><T><Y><S><V><T><L><V><N><E><E><K><N><I><N><A><V><I><K><C><P><D><D><Q><F><I><L><D><A><A><E><E><Q><G><I><E><L><P><Y><S><C><R><A><G><A><C><S><T><C><A><G><K><V><L><S><G><T><I><D><Q><S><E><Q><S><F><L><D><D><D><Q><M><G><A><G><F><L><L><T><C><V><A><Y><P><T><S><D><C><K><V><Q><T><H><A><E><D><D><L><Y>
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP>
P13106
O76616
PID3_CAEEL
piRNA-induced silencing defective protein 3
Caenorhabditis
<M><V><A><H><Q><K><A><D><F><K><S><K><W><A><M><V><V><T><V><N><N><L><N><D><K><K><R><A><D><L><R><E><F><S><E><W><F><I><E><T><L><R><L><E><G><A><F><I><G><H><Y><F><N><Y><E><A><A><P><V><T><I><V><E><T><L><P><G><N><F><D><S><C><T><N><A><Y><Q><K><I><H><K><E><H><P><Q><V><V><L><V><V><H><I><L><P><Q><S><Q><S><N><E><Y><E><W><M><K><V><L...
Component of the pid-1 and tost-1 variants of the PETISCO complexes, which have roles in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) and embryogenesis, respectively . Within the pid-1 variant of the PETISCO complex may stab...
O76616
B8GUJ5
RUVA_THISH
Holliday junction ATP-dependent DNA helicase RuvA
Thioalkalivibrio
<M><I><G><R><L><R><G><E><L><V><S><K><Q><P><P><F><L><L><L><D><V><Q><G><V><G><Y><E><I><E><A><P><L><S><T><F><Y><D><L><P><E><P><G><G><Q><V><T><L><H><T><H><L><H><V><R><E><D><A><H><V><L><Y><G><F><A><S><E><S><E><R><A><L><F><R><S><L><I><K><V><T><G><V><G><A><K><M><A><L><A><I><L><S><G><M><T><A><S><E><F><S><R><C><V><M><D><G><D><V...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA...
B8GUJ5
P0ADR2
YGDD_ECOLI
UPF0382 inner membrane protein YgdD
Escherichia
<M><T><S><R><F><M><L><I><F><A><A><I><S><G><F><I><F><V><A><L><G><A><F><G><A><H><V><L><S><K><T><M><G><A><V><E><M><G><W><I><Q><T><G><L><E><Y><Q><A><F><H><T><L><A><I><L><G><L><A><V><A><M><Q><R><R><I><S><I><W><F><Y><W><S><S><V><F><L><A><L><G><T><V><L><F><S><G><S><L><Y><C><L><A><L><S><H><L><R><L><W><A><F><V><T><P><V><G><G><V...
May be a peptide transporter or a protein that facilitates peptide internalization .<BOP>
P0ADR2
B1L108
LGT_CLOBM
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Clostridium
<M><N><P><I><A><F><H><V><G><N><L><A><I><R><W><Y><G><V><I><I><S><I><G><A><A><L><G><L><L><L><A><M><Y><N><C><K><I><R><E><A><S><Y><D><E><F><I><N><M><F><L><I><A><F><P><S><A><I><I><G><A><R><L><Y><Y><V><I><F><E><F><E><D><Y><R><D><N><L><I><N><I><F><N><T><R><Q><G><G><L><A><I><H><G><G><I><I><F><G><V><L><A><V><Y><I><Y><L><K><Y><R...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
B1L108
Q8TS71
MTBC2_METAC
Dimethylamine corrinoid protein 2
Methanosarcina
<M><A><S><K><E><E><L><L><Q><E><L><S><D><A><I><V><S><C><K><K><D><R><V><I><A><A><V><E><K><A><K><E><V><M><E><P><A><E><I><I><E><K><G><L><A><A><G><M><N><Q><V><G><T><L><F><E><R><G><K><L><F><L><P><H><V><M><M><A><A><D><S><M><T><A><G><V><N><I><L><E><A><E><M><P><A><G><T><E><T><K><K><L><G><V><I><V><N><G><T><V><E><G><D><V><H><D><I...
Acts as a methyl group carrier between MtbB and MtbA.<BOP>
Q8TS71
B3EFY2
RL13_CHLL2
50S ribosomal protein L13
Chlorobium
<M><S><K><T><L><S><F><K><T><Y><S><A><K><P><A><E><V><E><R><K><W><Y><V><I><D><A><E><D><Q><I><L><G><R><M><A><A><E><I><A><K><V><L><R><G><K><H><K><P><Q><F><T><P><H><I><D><T><G><D><F><I><V><V><T><N><A><E><K><V><A><L><S><G><K><K><I><E><Y><K><T><Y><F><H><H><S><N><Y><P><G><G><G><K><F><D><H><V><K><D><L><L><K><K><K><P><E><K><V><I...
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.<BOP>
B3EFY2
A0A411PQN4
AGN8_PAEDI
Agnestins biosynthesis cluster protein L8
Paecilomyces
<M><A><K><D><P><T><F><E><E><V><T><G><C><Q><R><A><L><F><E><W><A><D><S><Y><D><T><K><D><W><E><R><L><K><K><C><V><A><P><T><L><R><I><D><Y><R><S><F><L><D><K><L><W><E><A><M><P><S><D><E><F><I><L><M><A><S><D><P><R><F><L><G><N><P><L><L><K><T><Q><H><F><V><G><L><S><T><W><Q><K><I><S><P><D><E><I><E><G><T><H><Q><L><R><V><P><H><Q><R><Y...
Dehydratase; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites . The pathway begins with the assembly and cyclization of atrochrysone thioester by the non-reducing polyketide synthase Agnpks1 . The atrochrysone carboxyl ACP thioesterase AgnL7 then breaks the thioester ...
A0A411PQN4
A5F0H9
ECTC_VIBC3
N-acetyldiaminobutyrate dehydratase
Vibrio
<M><I><V><R><T><L><E><E><C><R><Q><S><E><R><R><V><V><A><E><N><W><E><S><V><R><M><L><L><K><D><D><H><M><G><F><S><F><H><I><T><T><I><Y><A><N><T><Q><T><H><I><H><Y><R><N><H><L><E><S><V><Y><C><M><S><G><E><G><E><I><E><V><V><G><G><K><T><Y><P><I><Q><P><G><T><L><Y><I><L><D><Q><H><D><E><H><Y><L><R><A><F><S><S><E><M><V><M><A><C><V><F...
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.<BOP>
A5F0H9
B5YDV7
RS8_DICT6
30S ribosomal protein S8
Dictyoglomus
<M><T><V><T><D><P><I><A><D><M><L><V><R><I><K><N><A><S><M><R><R><H><P><T><V><D><V><P><Y><S><K><M><K><E><K><I><L><E><I><L><L><R><E><G><Y><I><A><R><Y><E><V><I><G><E><I><P><Q><K><Y><I><R><V><Y><L><K><Y><K><G><K><T><P><V><I><Q><D><V><K><R><V><S><K><P><G><R><R><Y><Y><V><N><K><E><E><I><P><R><V><L><G><G><L><G><I><A><I><L><S><T...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
B5YDV7
Q18H64
FLPA_HALWD
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
Haloquadratum
<M><K><A><S><S><S><L><P><D><G><V><Q><R><R><Q><F><D><N><R><S><R><L><T><T><H><G><T><T><V><Y><G><E><P><R><D><T><D><G><W><R><L><W><D><A><G><R><S><K><L><G><A><M><F><K><L><D><I><E><T><G><L><T><G><G><E><S><I><L><Y><L><G><A><A><S><G><T><T><V><S><H><V><A><D><F><A><G><P><T><Y><A><I><E><F><A><P><R><P><V><R><D><L><L><E><V><A><T><T...
Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the ...
Q18H64
B2V847
DXR_SULSY
2-C-methyl-D-erythritol 4-phosphate synthase
unclassified Sulfurihydrogenibium
<M><L><K><V><G><I><L><G><S><T><G><S><V><G><S><Q><A><L><D><V><I><R><K><Y><K><D><Q><I><K><V><E><L><L><G><A><S><K><L><S><E><N><L><I><N><Q><I><K><E><F><K><P><S><Y><V><Y><V><E><N><A><E><E><K><S><I><D><D><I><K><V><L><V><G><E><D><G><L><R><R><A><V><N><L><D><L><D><L><F><I><N><A><I><A><G><I><K><G><I><L><P><T><Y><L><L><L><K><Y><N...
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
B2V847
B3QQD1
APT_CHLP8
Adenine phosphoribosyltransferase
Chlorobaculum
<M><P><I><K><S><R><I><R><T><V><P><D><Y><P><K><K><G><I><M><F><R><D><I><T><T><L><I><K><D><P><V><G><F><R><L><V><I><D><N><M><T><Q><H><Y><L><S><N><G><I><D><F><D><V><I><V><G><I><E><A><R><G><F><I><I><G><G><A><L><S><Y><T><L><G><K><G><F><V><P><V><R><K><P><G><K><L><P><A><D><V><V><Q><L><E><Y><D><L><E><Y><G><S><D><K><I><E><M><H><T...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
B3QQD1
A9IHE2
SYDND_BORPD
Non-discriminating aspartyl-tRNA synthetase
Bordetella
<M><R><T><C><Y><T><G><E><V><C><R><D><H><L><G><Q><T><V><T><L><Y><G><W><V><N><R><R><R><D><H><G><G><V><I><F><I><D><L><R><D><R><A><G><L><A><Q><I><V><F><D><P><D><N><A><A><F><A><T><A><E><R><L><R><N><E><F><C><I><R><V><T><G><L><V><R><P><R><P><E><G><T><A><N><P><E><L><A><S><G><E><V><E><V><L><C><K><E><V><E><I><L><N><A><S><I><T><P...
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP>
A9IHE2
Q4K6J1
MURD_PSEF5
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Pseudomonas
<M><S><L><I><A><S><D><H><F><R><I><V><V><G><L><G><K><S><G><M><S><L><V><R><F><L><A><S><R><G><V><A><F><A><V><A><D><T><R><E><N><P><P><E><L><A><T><L><R><R><D><Y><P><Q><V><E><V><R><C><G><E><L><D><V><D><F><L><C><R><A><D><E><L><Y><V><S><P><G><L><A><L><A><T><P><A><L><Q><A><A><A><A><R><G><V><K><L><S><G><D><I><E><L><F><A><R><N><A...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q4K6J1
P9WMD2
CHLER_MYCTO
HTH-type transcriptional repressor MT1396
Mycobacterium tuberculosis complex
<M><Q><T><T><P><G><K><R><Q><R><R><Q><R><G><S><I><N><P><E><D><I><I><S><G><A><F><E><L><A><Q><Q><V><S><I><D><N><L><S><M><P><L><L><G><K><H><L><G><V><G><V><T><S><I><Y><W><Y><F><R><K><K><D><D><L><L><N><A><M><T><D><R><A><L><S><K><Y><V><F><A><T><P><Y><I><E><A><G><D><W><R><E><T><L><R><N><H><A><R><S><M><R><K><T><F><A><D><N><P><V...
Negatively regulates the expression of the efflux pump MT0201 upon chloramphenicol exposure. Acts by binding to the MT0201 promoter region.<BOP>
P9WMD2
A5CRA6
HRCA_CLAM3
Heat-inducible transcription repressor HrcA
Clavibacter
<M><V><S><E><R><G><L><D><V><L><R><V><I><V><Q><D><Y><V><S><S><R><E><P><V><G><S><K><S><I><V><E><R><H><A><F><G><V><S><A><A><T><I><R><N><D><M><A><L><L><E><E><E><E><L><I><A><A><P><H><T><S><S><G><R><V><P><T><D><K><G><Y><R><L><F><V><D><Q><L><A><D><V><R><P><L><T><P><A><Q><R><Q><A><I><H><V><F><L><G><E><S><V><D><L><D><D><V><L><A...
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP>
A5CRA6
D3E3N9
EF2_METRM
Elongation factor 2
Methanobrevibacter
<M><S><R><R><D><K><M><I><A><K><I><K><E><L><M><Y><K><P><E><Y><I><R><N><I><G><I><C><A><H><I><D><H><G><K><T><T><L><S><D><N><L><L><A><G><A><G><L><I><S><E><D><L><A><G><E><A><L><G><M><D><T><K><K><D><E><Q><E><R><G><I><T><I><D><A><A><N><A><S><M><V><Q><E><Y><E><G><E><Q><Y><L><I><N><L><I><D><T><P><G><H><V><D><F><G><G><D><V><T><R...
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective...
D3E3N9
B3QQS6
RL11_CHLP8
50S ribosomal protein L11
Chlorobaculum
<M><A><K><K><I><T><G><F><I><K><L><Q><I><P><A><G><G><A><N><P><A><P><P><V><G><P><A><L><G><Q><K><G><V><N><I><M><E><F><C><K><Q><F><N><A><K><T><Q><S><E><A><G><M><I><I><P><V><V><I><T><V><F><S><D><K><S><F><T><F><V><T><K><T><P><P><A><A><V><L><L><L><K><E><A><K><L><Q><K><G><S><G><E><P><N><R><N><K><V><G><T><V><T><M><E><Q><V><R><K...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
B3QQS6
A6LTK6
ILVD_CLOB8
Dihydroxy-acid dehydratase
Clostridium
<M><R><S><D><V><I><T><K><G><S><K><S><A><P><Q><R><S><L><L><S><A><L><G><L><T><K><E><E><M><E><R><P><L><V><G><I><V><S><S><Q><N><D><I><V><P><G><H><M><N><L><D><K><I><V><E><A><V><K><M><G><V><S><M><A><G><G><T><P><I><V><F><P><A><I><A><V><C><D><G><I><A><M><G><H><E><G><M><K><Y><S><L><V><T><R><D><L><I><A><D><S><T><E><A><M><A><M><A...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
A6LTK6
C1DSX5
KAD_AZOVD
Adenylate monophosphate kinase
Azotobacter
<M><R><V><I><L><L><G><A><P><G><A><G><K><G><T><Q><A><R><F><I><T><E><R><F><G><I><P><Q><I><S><T><G><D><M><L><R><A><A><V><K><A><G><S><P><L><G><L><K><V><K><G><V><M><D><S><G><G><L><V><S><D><D><I><I><I><D><L><I><R><E><R><I><A><Q><P><D><C><A><R><G><F><L><F><D><G><F><P><R><T><I><P><Q><A><E><A><L><R><D><A><G><V><S><I><D><H><V><L...
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP>
C1DSX5
A3CRB1
MNMG_STRSV
Glucose-inhibited division protein A
Streptococcus
<M><S><H><N><F><T><E><S><Y><D><I><I><V><I><G><A><G><H><A><G><V><E><A><S><L><A><A><S><R><M><G><C><K><V><L><L><A><T><I><N><I><E><M><L><A><F><M><P><C><N><P><S><I><G><G><S><A><K><G><I><V><V><R><E><V><D><A><L><G><G><E><M><A><K><N><I><D><K><S><Y><I><Q><M><K><M><L><N><T><G><K><G><P><A><V><R><A><L><R><A><Q><A><D><K><E><L><Y><S...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
A3CRB1
B1A923
ATPI_CARPA
F-ATPase subunit IV
Carica
<M><D><V><I><S><C><S><S><N><T><L><K><G><L><Y><D><I><S><G><V><E><V><G><Q><H><L><Y><W><Q><I><G><G><L><Q><V><H><A><Q><V><L><I><T><S><W><V><V><I><A><I><L><L><G><S><A><I><I><A><V><R><N><P><Q><T><I><P><T><A><G><Q><N><F><F><E><Y><V><L><E><F><I><R><D><V><S><K><T><Q><I><G><E><E><Y><G><P><W><V><P><F><I><G><T><M><F><L><F><I><F><V...
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP>
B1A923
Q2K7G6
COBT_RHIEC
N(1)-alpha-phosphoribosyltransferase
Rhizobium
<M><S><V><S><G><L><P><F><D><D><F><R><T><L><L><R><E><L><P><G><P><D><A><R><A><L><A><A><A><R><E><R><D><A><Q><L><T><K><P><P><G><A><L><G><R><L><E><E><I><A><F><W><L><A><A><W><T><G><R><A><P><A><V><N><R><P><L><V><A><I><F><A><G><N><H><G><V><T><R><H><G><I><T><P><F><P><P><A><V><T><Q><Q><M><V><E><N><F><A><A><G><G><A><A><I><N><Q><I...
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP>
Q2K7G6
A9IZA2
TRMD_BART1
tRNA [GM37] methyltransferase
Bartonella
<M><K><F><Q><A><R><V><L><T><L><Y><P><E><M><F><P><G><F><L><G><Y><S><L><A><G><H><A><L><E><R><G><I><W><S><L><E><T><V><Q><I><R><D><F><A><L><D><K><H><H><S><V><D><D><T><P><A><G><G><G><A><G><M><V><M><R><A><D><V><L><A><A><A><L><D><H><C><P><Q><D><S><P><R><L><L><M><S><P><R><G><R><P><F><D><Q><A><Y><A><R><R><L><A><D><D><S><G><I><T...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
A9IZA2
B0SXB0
THIG_CAUSK
Thiazole synthase
unclassified Caulobacter
<M><N><A><H><V><P><P><E><S><V><S><A><A><E><D><S><W><T><V><A><G><R><T><F><R><S><R><L><I><V><G><T><G><K><Y><K><D><Y><A><T><N><A><A><A><A><K><A><A><G><A><E><I><V><T><V><A><V><R><R><V><N><L><T><D><P><T><Q><P><L><L><I><D><Y><V><K><P><T><E><F><T><Y><L><P><N><T><A><G><C><F><T><G><E><D><A><V><R><T><L><R><L><A><R><E><A><G><G><W...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
B0SXB0
Q93Z29
ALMT5_ARATH
Aluminum-activated malate transporter 5
Arabidopsis
<M><G><G><K><M><G><S><V><P><E><Q><N><T><E><K><L><L><W><Q><S><S><D><V><A><D><S><R><D><S><K><F><R><C><C><S><W><R><A><L><Y><E><A><P><A><K><L><Y><A><L><G><H><S><D><R><R><K><L><Y><F><S><I><K><M><G><I><A><L><A><L><C><S><F><V><I><F><L><K><E><P><L><Q><D><A><S><K><F><A><V><W><A><I><L><T><V><V><L><I><F><E><Y><Y><V><G><A><T><L><V...
Malate transporter.<BOP>
Q93Z29
C6E4P3
RS8_GEOSM
30S ribosomal protein S8
unclassified Geobacter
<M><C><M><T><D><P><V><A><D><M><L><T><R><I><R><N><A><G><M><A><K><H><Q><K><V><D><I><P><S><S><N><L><K><V><S><L><A><T><V><L><R><A><E><G><F><I><K><N><F><K><V><I><A><D><N><K><Q><G><I><L><R><V><Y><L><K><F><I><D><E><K><E><P><V><I><N><E><I><K><R><I><S><K><P><G><G><R><V><Y><V><N><S><D><K><I><K><Q><V><K><N><G><L><G><V><A><I><L><S...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
C6E4P3
Q8DEC6
OBG_VIBVU
GTP-binding protein Obg
Vibrio
<M><K><F><V><D><E><A><V><I><K><V><Q><A><G><D><G><G><N><G><V><V><S><F><W><R><E><K><F><V><T><K><G><G><P><D><G><G><D><G><G><D><G><G><D><V><Y><I><Q><A><D><E><N><L><N><T><L><I><D><Y><R><F><Q><R><F><Y><E><A><E><R><G><Q><N><G><S><G><G><N><C><T><G><K><R><G><K><D><I><T><L><R><V><P><V><G><T><R><A><V><D><I><H><T><N><E><I><V><A><E...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
Q8DEC6
A9XFZ7
DEF_COPTR
Defensin coprisin
Copris
<M><A><K><L><I><A><F><A><L><V><A><S><L><C><L><S><M><V><L><C><N><P><L><P><E><E><V><Q><E><E><G><L><V><R><Q><K><R><V><T><C><D><V><L><S><F><E><A><K><G><I><A><V><N><H><S><A><C><A><L><H><C><I><A><L><R><K><K><G><G><S><C><Q><N><G><V><C><V><C><R><N>
Potent broad-spectrum antibacterial peptide against both Gram-positive (B.subtilis, S.epidermidis, and S.aureus) and Gram-negative bacteria (E.coli, S.typhimurium, and P.aeruginosa) . Is also active against all antibiotic-resistant bacterial strains tested . Induces apoptosis in C.albicans, but does not disrupt the fun...
A9XFZ7
Q8VUS8
QADG_PARDE
Quinohemoprotein amine dehydrogenase catalytic subunit
Paracoccus
<M><N><A><L><V><G><C><T><T><S><F><D><P><G><W><E><V><D><A><F><G><A><V><S><N><L><C><Q><P><M><E><A><D><L><Y><G><C><A><D><P><C><W><W><P><A><Q><V><A><D><T><L><N><T><Y><P><N><W><S><A><G><A><D><D><V><M><Q><D><W><R><K><L><Q><S><V><F><P><E><T><K><G><S><S>
Catalyzes the oxidative deamination of a wide range of primary aliphatic and aromatic amines . The physiological electron acceptor is the constitutive cytochrome c550 .<BOP>
Q8VUS8
P19237
TNNI1_HUMAN
Troponin I, slow-twitch isoform
Homo
<M><P><E><V><E><R><K><P><K><I><T><A><S><R><K><L><L><L><K><S><L><M><L><A><K><A><K><E><C><W><E><Q><E><H><E><E><R><E><A><E><K><V><R><Y><L><A><E><R><I><P><T><L><Q><T><R><G><L><S><L><S><A><L><Q><D><L><C><R><E><L><H><A><K><V><E><V><V><D><E><E><R><Y><D><I><E><A><K><C><L><H><N><T><R><E><I><K><D><L><K><L><K><V><M><D><L><R><G><K...
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.<BOP>
P19237
A8AA22
RNP1_IGNH4
Rpp29
Ignicoccus
<M><K><H><T><P><K><N><V><I><Y><H><N><L><V><G><L><R><V><E><V><L><A><H><P><D><P><S><M><K><G><L><K><G><R><I><I><D><E><S><K><S><F><L><T><I><E><K><D><N><G><E><L><V><K><V><Q><K><L><G><T><F><V><L><V><L><P><S><G><R><K><V><E><V><R><G><E><L><L><R><G><R><P><E><E><R><L><K><K><F><L><K><A>
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.<BOP>
A8AA22
Q54K91
ACH1_DICDI
Acetyl-CoA deacylase
Dictyostelium
<M><H><K><I><V><Q><Q><G><S><K><S><L><I><E><S><R><I><K><R><K><S><L><L><S><K><V><V><T><D><V><S><Q><L><I><P><Y><F><Q><N><G><H><Y><V><S><M><G><G><F><A><G><T><G><Y><P><K><V><V><P><I><A><L><A><D><H><V><E><K><N><G><L><Q><G><K><L><K><M><N><L><F><V><G><A><S><V><G><P><E><T><E><D><R><W><A><M><L><D><M><I><D><K><R><Y><P><H><Q><N><G...
Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.<BOP>
Q54K91
A1C777
EIF3D_ASPCL
Eukaryotic translation initiation factor 3 subunit D
Aspergillus subgen. Fumigati
<M><A><P><V><S><I><A><D><L><V><A><A><L><P><S><E><D><S><W><G><P><A><T><P><S><D><N><M><L><E><G><V><P><Y><A><P><F><S><K><G><D><K><L><G><R><M><A><D><W><T><S><D><S><K><D><R><D><R><A><G><R><Q><A><Y><N><R><N><Y><R><D><Q><Q><V><Y><G><A><G><T><S><S><L><F><N><V><Q><V><A><E><D><E><S><S><F><S><V><V><D><N><T><R><T><T><T><K><R><T><F...
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically target...
A1C777
O94295
PUS2_SCHPO
tRNA-uridine isomerase 2
Schizosaccharomyces
<M><T><S><I><S><K><R><K><N><Q><Q><E><H><I><P><A><E><D><L><E><T><P><K><L><P><K><R><E><K><I><E><G><T><K><E><S><N><K><V><R><I><I><I><L><L><G><Y><S><G><Y><G><Y><H><G><I><Q><I><N><N><P><L><K><T><I><E><G><D><V><V><A><V><L><K><K><L><G><Y><L><K><T><N><N><I><D><A><E><H><L><C><I><A><R><A><A><R><T><D><K><G><V><H><T><L><R><N><L><I...
Formation of pseudouridine at positions 27 and 28 in the anticodon stem and loop of transfer RNAs; at positions 34 and 36 of intron-containing precursor tRNA(Ile) and at position 35 in the intron-containing tRNA(Tyr).<BOP>
O94295
O64896
TPPA_ARATH
Trehalose 6-phosphate phosphatase
Arabidopsis
<M><D><M><K><S><G><H><S><S><P><V><M><T><D><S><P><P><I><S><N><S><R><L><T><I><R><Q><N><R><L><P><Y><S><S><A><A><A><T><A><I><S><Q><N><N><N><L><L><L><T><V><P><R><K><K><T><G><I><L><D><D><V><K><S><N><G><W><L><D><A><M><K><S><S><S><P><P><P><T><I><L><N><K><D><N><L><S><N><D><A><T><D><M><T><Y><R><E><W><M><Q><L><K><Y><P><S><A><L><T...
Removes the phosphate from trehalose 6-phosphate to produce free trehalose. Trehalose accumulation in plant may improve abiotic stress tolerance.<BOP>
O64896
Q11CM8
DCUP_CHESB
Uroporphyrinogen decarboxylase
unclassified Chelativorans
<M><A><E><R><K><L><L><E><A><L><N><G><R><T><V><F><P><P><P><I><W><L><M><R><Q><A><G><R><Y><L><P><E><Y><R><E><T><R><K><K><A><G><S><F><L><D><L><C><Y><N><P><E><L><A><V><E><V><T><L><Q><P><I><R><R><F><G><F><D><A><A><I><L><F><S><D><I><L><V><I><P><H><A><L><G><R><D><L><R><F><E><E><G><A><G><P><L><M><S><P><I><Q><A><N><E><I><P><G><L...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
Q11CM8
Q8AVR4
PDC10_XENLA
Programmed cell death protein 10
Xenopus
<M><R><M><T><M><E><E><M><K><N><E><A><E><T><T><S><M><V><S><M><P><L><Y><A><V><M><Y><P><V><F><N><E><L><E><R><V><N><L><S><A><A><Q><T><L><R><A><A><F><I><K><A><E><K><E><N><P><G><L><T><Q><D><I><I><T><K><I><L><E><K><K><S><V><E><V><N><F><T><E><S><L><L><R><M><A><A><D><D><V><E><E><Y><M><V><E><R><P><E><P><E><F><Q><E><L><N><E><K><A...
Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal cardiovascular development. Required for normal angiogenesis, ...
Q8AVR4
Q92C06
GCST_LISIN
Glycine cleavage system T protein
Listeria
<M><T><E><L><L><K><T><P><I><H><P><L><Y><A><K><Y><G><A><K><T><I><D><F><G><G><W><D><L><P><V><Q><F><A><G><I><K><A><E><H><E><A><V><R><T><D><A><G><L><F><D><V><S><H><M><G><E><I><L><V><E><G><P><D><S><T><S><Y><L><Q><Y><L><L><S><N><D><I><E><K><I><K><I><G><K><A><Q><Y><N><I><M><C><Y><E><T><G><G><T><V><D><D><L><V><V><Y><K><K><S><E...
The glycine cleavage system catalyzes the degradation of glycine.<BOP>
Q92C06
O31149
PT1_LISMO
Phosphotransferase system, enzyme I
Listeria
<M><A><K><E><L><K><G><I><A><A><S><D><G><I><A><I><A><K><A><Y><L><L><V><E><P><D><L><S><Y><E><K><T><E><V><T><D><V><E><S><E><V><K><R><F><E><S><A><L><E><V><S><R><T><E><L><S><M><I><R><E><K><A><A><K><D><L><G><E><D><K><A><Q><I><F><D><A><H><L><L><V><L><N><D><P><E><L><T><G><P><I><E><E><S><I><K><N><S><K><T><N><A><E><T><A><L><Q><E...
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phos...
O31149
B0BQ46
PURT_ACTPJ
Phosphoribosylglycinamide formyltransferase 2
Actinobacillus
<M><T><T><I><G><T><P><L><R><P><N><A><T><K><V><M><M><L><G><S><G><E><L><G><K><E><V><V><I><E><L><Q><R><L><G><V><E><V><I><A><V><D><R><Y><E><N><A><P><A><Q><Q><V><A><H><R><A><Y><T><I><S><M><L><D><G><A><A><L><R><A><L><A><E><K><E><K><P><D><F><I><V><P><E><V><E><A><I><A><T><A><T><L><V><E><L><E><Q><E><G><Y><N><V><V><P><T><A><K><A...
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP>
B0BQ46
Q4UMR4
RL6_RICFE
50S ribosomal protein L6
spotted fever group
<M><S><R><V><G><K><L><P><I><T><I><P><E><G><V><K><V><G><L><N><D><L><E><V><K><I><S><G><P><K><G><E><L><S><K><T><F><K><G><N><I><A><I><S><L><E><E><N><K><L><L><V><K><P><L><A><A><N><K><N><A><R><A><M><W><G><T><A><R><S><I><I><S><N><M><V><T><G><V><K><E><G><F><K><L><K><L><E><I><N><G><V><G><Y><R><A><M><V><K><G><K><Y><L><N><L><M><L...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q4UMR4
Q9Z6T0
DEGPL_CHLPN
Protease Do
Chlamydia
<M><I><T><K><Q><L><R><S><W><L><A><V><L><V><G><S><S><L><L><A><L><P><L><S><G><Q><A><V><G><K><K><E><S><R><V><S><E><L><P><Q><D><V><L><L><K><E><I><S><G><G><F><S><K><V><A><T><K><A><T><P><A><V><V><Y><I><E><S><F><P><K><S><Q><A><V><T><H><P><S><P><G><R><R><G><P><Y><E><N><P><F><D><Y><F><N><D><E><F><F><N><R><F><F><G><L><P><S><Q><R...
Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.<BOP>
Q9Z6T0
Q03QU1
DNAK_LEVBA
Heat shock protein 70
Levilactobacillus
<M><A><S><N><K><I><I><G><I><D><L><G><T><T><N><S><A><V><A><V><L><E><G><S><T><P><K><I><I><A><N><K><E><G><A><R><T><T><P><S><V><V><A><F><K><D><G><E><T><Q><V><G><E><V><A><K><R><Q><A><I><T><N><P><N><T><I><S><S><I><K><S><H><M><G><E><A><G><Y><K><V><S><V><D><G><K><D><Y><T><P><Q><Q><V><S><A><M><I><L><Q><H><L><K><A><F><A><E><D><Y...
Acts as a chaperone.<BOP>
Q03QU1
B2USG1
ILVC_HELPS
Ketol-acid reductoisomerase type I
Helicobacter
<M><A><L><P><V><Y><Y><D><K><D><I><D><L><G><V><I><Q><S><L><Q><V><G><I><I><G><Y><G><A><Q><G><E><A><Q><A><L><N><L><R><D><S><K><V><K><V><R><I><G><L><Y><Q><G><S><L><S><V><P><K><A><K><A><E><G><F><E><V><L><E><V><K><E><L><V><Q><Q><S><D><L><I><M><A><L><L><P><D><E><L><H><K><E><V><L><E><K><E><V><I><P><F><L><K><E><G><Q><I><V><G><F...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
B2USG1
A1SDP0
ARAA_NOCSJ
L-arabinose isomerase
Nocardioides
<M><T><H><H><P><D><E><L><E><I><W><F><L><T><G><S><Q><H><L><Y><G><P><E><V><I><D><Q><V><A><E><H><A><A><R><I><V><A><A><L><D><A><S><P><H><L><P><V><R><V><V><S><K><P><V><L><T><E><T><D><S><I><R><R><A><L><L><D><A><T><A><T><D><S><C><V><G><V><I><A><W><M><H><T><F><S><P><A><K><M><W><I><T><G><L><D><A><L><R><K><P><L><L><H><L><H><T><Q...
Catalyzes the conversion of L-arabinose to L-ribulose.<BOP>
A1SDP0
A6TM76
TRPB_ALKMQ
Tryptophan synthase beta chain
Alkaliphilus
<M><M><K><V><K><E><L><P><K><K><F><G><K><F><G><G><Q><F><V><P><E><T><L><M><N><A><L><I><E><L><E><R><Q><F><I><Q><T><K><E><D><D><E><F><Q><E><M><Y><R><Y><Y><V><R><E><Y><S><G><R><P><T><P><L><Y><Y><A><E><N><L><T><K><K><L><G><G><G><K><I><Y><L><K><R><E><D><L><N><H><T><G><A><H><K><I><N><N><V><I><G><Q><V><L><L><A><R><K><M><K><K><K...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
A6TM76
Q0KBK6
MNMC_CUPNH
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Cupriavidus
<M><P><R><A><L><E><P><A><E><P><I><L><S><A><E><G><I><P><Y><S><P><R><Y><D><D><V><Y><H><S><T><E><G><G><L><A><Q><A><A><H><V><F><L><G><G><N><G><L><P><Q><A><W><A><G><Q><R><Q><F><V><I><V><E><T><G><F><G><L><G><L><N><F><L><A><T><W><Q><A><W><R><A><D><P><Q><R><C><G><T><L><H><F><V><S><I><E><K><H><P><F><T><R><E><G><L><A><Q><L><H><A...
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s...
Q0KBK6
Q5JHS5
PAN_THEKO
Proteasome regulatory particle
Thermococcus
<M><S><I><E><N><T><D><V><H><P><E><G><Y><D><D><Y><V><T><F><L><K><R><R><I><R><Q><L><E><L><Q><V><R><T><L><E><A><D><K><E><R><L><E><R><E><L><S><R><L><R><M><E><M><S><R><L><R><Q><P><P><A><F><A><G><N><V><I><E><V><L><D><D><E><R><A><I><V><Q><N><Y><N><G><P><R><F><V><V><R><I><A><P><W><I><E><R><D><K><L><K><P><G><A><R><V><A><L><D><Q...
ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. ...
Q5JHS5
A9N514
ULAF_SALPB
Phosphoribulose isomerase
Salmonella
<M><Q><K><L><K><Q><Q><V><F><D><A><N><M><D><L><P><R><Y><G><L><V><T><F><T><W><G><N><V><S><A><I><D><R><E><R><G><L><V><V><I><K><P><S><G><V><A><Y><E><T><M><K><V><D><D><M><V><V><V><D><M><D><G><K><V><V><E><G><R><Y><R><P><S><S><D><T><A><T><H><L><A><L><Y><Q><R><Y><P><S><L><G><G><V><V><H><T><H><S><T><H><A><T><A><W><A><Q><A><G><M...
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization.<BOP>
A9N514
Q7VKU5
DUSC_HAEDU
tRNA-dihydrouridine synthase C
Haemophilus
<M><I><K><S><I><P><R><I><M><L><A><P><M><Q><G><V><L><D><P><F><M><R><K><L><L><T><A><Y><N><D><Y><D><L><C><V><S><E><F><V><R><V><V><D><Q><R><L><P><K><K><T><F><Y><R><L><A><P><E><L><L><Q><G><G><L><T><D><S><G><T><P><I><R><V><Q><L><L><G><Q><Y><P><Q><W><L><A><E><N><A><Q><L><A><I><E><L><G><S><Y><G><I><D><F><N><C><G><C><P><S><K><T...
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.<BOP>
Q7VKU5
C0R4Y2
NUOB_WOLWR
NDH-1 subunit B
unclassified Wolbachia
<M><T><N><Q><I><L><S><N><D><D><W><G><R><Y><K><K><E><G><F><L><V><T><K><F><G><D><L><T><D><Y><V><M><N><W><A><R><S><G><S><L><W><P><M><T><F><G><L><A><C><C><A><V><E><M><M><H><T><A><S><S><R><Y><D><L><D><R><Y><G><I><M><F><R><A><S><P><R><Q><S><D><V><M><I><V><A><G><T><L><T><N><K><M><A><A><A><L><R><K><V><Y><D><Q><M><A><D><P><K><Y...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
C0R4Y2
O13924
HASP_SCHPO
Serine/threonine-protein kinase haspin homolog hrk1
Schizosaccharomyces
<M><E><S><R><S><K><V><K><T><Y><G><K><N><R><R><Y><I><N><K><D><I><E><I><W><A><S><L><D><E><R><P><C><A><L><K><P><R><N><I><E><N><F><N><N><Q><E><R><S><D><L><E><H><I><H><S><K><P><K><K><D><S><L><L><S><W><N><I><L><L><K><K><G><S><Y><K><E><N><E><L><L><A><K><R><N><Q><N><L><V><P><T><V><I><I><P><A><S><P><R><D><N><A><S><K><S><V><V><S...
Serine/threonine haspin-like protein kinase involved in cell cycle regulation. Acts in chromosomal passenger complex (CPC) targeting to centromeres by phosphorylating histone H3 at 'Thr3' (H3T3ph).<BOP>
O13924
B1IAU3
RLMN_STRPI
tRNA m2A37 methyltransferase
Streptococcus
<M><K><P><S><I><H><S><L><T><H><Q><T><M><Q><E><W><V><L><E><Q><G><E><K><K><F><R><A><D><Q><I><W><E><W><L><Y><R><K><R><V><Q><S><F><E><E><M><T><N><L><S><K><D><L><I><A><K><L><N><D><Q><F><V><V><N><P><L><K><Q><R><I><V><Q><E><S><A><D><G><T><V><K><Y><L><F><E><L><P><D><G><M><L><I><E><T><V><L><M><R><Q><H><Y><G><L><S><V><C><V><T><T...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.<BOP>
B1IAU3
C3L062
THIM1_CLOB6
4-methyl-5-beta-hydroxyethylthiazole kinase 1
Clostridium
<M><E><N><K><N><V><I><Q><K><M><R><E><K><T><P><L><I><H><C><I><T><N><Y><V><T><I><N><D><C><A><N><I><L><L><S><F><G><A><S><P><A><M><C><E><A><Y><D><E><V><Y><D><F><V><S><I><S><S><A><L><Y><I><N><L><G><T><L><T><K><E><Q><E><T><A><A><V><L><A><S><I><S><A><K><N><H><N><V><P><V><V><I><D><P><V><G><C><P><A><I><K><R><K><V><E><V><I><N><R...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
C3L062
A6TKT6
HIS6_ALKMQ
ImGP synthase subunit HisF
Alkaliphilus
<M><I><T><K><R><I><I><P><C><L><D><V><R><K><G><R><V><V><K><G><V><N><F><V><D><I><K><D><A><G><D><P><V><A><L><A><R><A><Y><N><D><Q><G><A><D><E><I><V><F><L><D><I><T><A><S><H><E><E><R><Y><I><L><L><D><V><V><K><K><T><S><E><E><I><F><I><P><L><T><V><G><G><G><I><R><T><V><E><D><M><R><Q><I><I><K><S><G><A><D><K><V><S><I><N><S><S><A><V...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP>
A6TKT6
Q5NQ50
RL6_ZYMMO
50S ribosomal protein L6
Zymomonas
<M><S><R><I><G><K><K><P><V><A><I><P><T><G><V><T><A><N><I><A><D><G><V><L><S><V><K><G><P><K><G><E><L><S><M><P><L><S><S><E><V><T><Y><S><L><E><D><G><Q><L><S><V><Q><P><V><N><D><T><K><R><A><R><S><F><W><G><M><Q><R><T><L><V><Q><N><L><I><D><G><V><T><Q><G><Y><S><K><T><L><Q><I><T><G><V><G><Y><R><A><A><S><Q><G><K><T><L><K><L><Q><L...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q5NQ50
Q64687
SIA8A_MOUSE
Sialyltransferase St8Sia I
Mus
<M><S><P><C><G><R><A><L><H><T><S><R><G><A><M><A><M><L><A><R><K><F><P><R><T><R><L><P><V><G><A><S><A><L><C><V><V><V><L><C><W><L><Y><I><F><P><V><Y><R><L><P><N><E><K><E><I><V><Q><G><V><L><A><Q><R><T><A><W><R><T><N><Q><T><S><A><S><L><F><R><R><Q><M><E><D><C><C><D><P><A><H><L><F><A><M><T><K><M><N><S><P><M><G><K><S><L><W><Y><D...
Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid . Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form G...
Q64687
Q65SS8
NRDR_MANSM
Transcriptional repressor NrdR
Basfia
<M><H><C><P><F><C><S><T><E><E><T><K><V><I><D><S><R><L><V><S><D><G><Y><Q><V><R><R><R><R><E><C><T><K><C><H><E><R><F><T><T><F><E><T><A><E><L><V><V><P><K><I><I><K><N><N><G><M><R><E><P><F><N><E><D><K><L><R><R><G><I><Q><H><A><L><E><K><R><P><V><S><A><D><D><V><E><K><A><I><S><H><I><T><H><Q><L><R><A><T><G><E><R><E><V><P><S><K><L...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
Q65SS8
Q3ARQ5
COBT_CHLCH
N(1)-alpha-phosphoribosyltransferase
Chlorobium
<M><K><E><K><L><E><T><L><L><A><A><I><Q><P><A><D><Q><T><L><R><Q><A><I><Q><A><H><L><D><D><L><T><K><P><Q><G><S><L><G><R><L><E><E><I><A><Q><Q><Y><I><L><A><T><G><Q><I><H><P><S><L><P><K><K><K><I><C><C><F><A><G><D><H><G><V><A><A><E><G><V><S><A><F><P><A><E><V><T><P><Q><M><V><Y><N><M><L><H><G><G><A><A><I><N><V><L><S><R><H><V><G...
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP>
Q3ARQ5
Q43309
1A14_ARATH
S-adenosyl-L-methionine methylthioadenosine-lyase 4
Arabidopsis
<M><V><Q><L><S><R><K><A><T><C><N><S><H><G><Q><V><S><S><Y><F><L><G><W><E><E><Y><E><K><N><P><Y><D><V><T><K><N><P><Q><G><I><I><Q><M><G><L><A><E><N><Q><L><C><F><D><L><L><E><S><W><L><A><Q><N><T><D><A><A><C><F><K><R><D><G><Q><S><V><F><R><E><L><A><L><F><Q><D><Y><H><G><L><S><S><F><K><N><A><F><A><D><F><M><S><E><N><R><G><N><R><V...
1-aminocyclopropane-1-carboxylate synthase (ACS) enzymes catalyze the conversion of S-adenosyl-L-methionine (SAM) into 1-aminocyclopropane-1-carboxylate (ACC), a direct precursor of ethylene.<BOP>
Q43309
B0U659
FTSB_XYLFM
Cell division protein FtsB
Xylella
<M><R><N><W><R><W><L><L><L><V><L><A><A><L><L><A><W><L><Q><H><R><F><W><F><G><P><G><N><S><G><E><V><R><M><L><Q><V><Q><I><V><Q><Q><H><Q><E><N><E><R><L><R><Q><R><N><A><S><L><A><A><E><V><K><N><L><K><D><G><D><A><A><I><E><E><R><A><R><S><E><L><G><M><I><K><P><G><E><I><F><Y><R><V><V><E><D><I><P><A><P><L><P><N><D><T><S><A><D><H><G...
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.<BOP>
B0U659
Q9EST2
HNMT_CAVPO
Histamine N-methyltransferase
Cavia
<M><A><S><S><M><R><S><L><F><S><D><H><G><R><Y><F><E><A><F><R><R><F><L><N><N><S><T><E><Y><Q><C><M><R><E><F><M><D><K><Q><L><P><G><I><I><A><R><I><G><G><S><K><S><E><I><K><V><L><S><I><G><G><G><A><G><E><M><D><L><H><I><L><S><K><V><K><A><Q><Y><P><G><V><H><I><I><N><E><V><V><E><P><S><A><E><Q><I><T><K><Y><K><E><L><V><A><K><T><S><N...
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.<BOP>
Q9EST2