accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
A9B496 | DNAA_HERA2 | Chromosomal replication initiator protein DnaA | Herpetosiphon | <M><D><T><K><Q><I><W><F><T><T><L><G><T><L><Q><N><Q><I><L><R><Y><D><Y><D><T><W><L><K><T><T><A><L><V><S><V><A><N><D><L><A><V><I><G><A><P><N><V><T><T><K><Q><V><I><E><D><R><F><M><S><V><L><R><R><A><L><G><E><V><L><G><Y><Q><V><N><V><R><V><I><I><S><S><A><T><P><A><P><S><E><P><V><A><V><T><P><S><E><P><S><P><T><T><E><V><A><E><P><S... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | A9B496 |
P51142 | DVL2_XENLA | Xdsh | Xenopus | <M><A><E><T><K><V><I><Y><H><L><D><E><E><E><T><P><Y><L><V><K><V><P><V><P><A><T><D><I><R><L><R><D><F><K><A><A><L><G><R><G><H><A><K><Y><F><F><K><A><M><D><Q><D><F><G><V><V><K><E><E><I><S><D><D><N><A><K><L><P><C><F><N><D><R><V><V><S><W><L><A><S><S><E><G><S><Q><P><D><S><A><P><P><A><P><A><T><E><V><R><P><E><P><P><P><P><V><P><P... | Involved in at least 2 independent signaling cascades, controlling cell fate via canonical Wnt signaling and cell polarity via a planar cell polarity (PCP) cascade. Acts synergistically with dal/dapple-like to activate Wnt signaling, stabilizing ctnnb1/beta-catenin and leading to dorsal axis formation. Also prevents de... | P51142 |
A6WKM0 | ERPA_SHEB8 | Iron-sulfur cluster insertion protein ErpA | Shewanella | <M><T><D><Q><A><D><T><A><M><P><I><Q><F><T><D><A><A><A><A><K><V><K><G><L><L><E><E><E><Q><N><P><A><L><K><L><R><V><Y><V><T><G><G><G><C><S><G><F><Q><Y><G><F><T><F><D><E><K><V><N><D><G><D><F><T><I><E><K><Q><G><V><L><L><V><V><D><P><M><S><L><Q><Y><L><V><G><G><E><V><D><Y><T><S><G><L><E><G><S><R><F><F><V><K><N><P><N><A><T><T><T... | Required for insertion of 4Fe-4S clusters for at least IspG.<BOP> | A6WKM0 |
Q861R7 | KANL2_CAPHI | Non-specific lethal 2 homolog | Capra | <M><N><R><I><R><I><H><V><L><P><T><N><R><G><R><I><T><P><V><P><R><S><Q><E><P><L><S><C><S><F><T><H><R><P><C><S><Q><P><R><L><E><G><Q><E><F><C><I><K><H><I><L><E><D><K><N><A><P><F><K><Q><C><S><Y><I><S><T><K><N><G><K><R><C><P><S><A><A><P><K><P><E><K><K><D><G><V><S><F><C><A><E><H><A><R><R><N><A><L><A><L><H><A><Q><M><K><K><T><N... | As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.<BOP> | Q861R7 |
A1W445 | HIS3_ACISJ | Phosphoribosyl-AMP cyclohydrolase | unclassified Acidovorax | <M><D><T><M><N><W><L><D><Q><V><K><W><D><A><Q><G><L><V><P><V><I><A><Q><E><A><A><T><G><D><V><L><M><F><A><W><M><N><R><E><A><L><A><K><T><A><E><L><G><R><A><V><Y><Y><S><R><S><R><G><K><L><W><F><K><G><E><E><S><G><H><V><Q><Q><V><H><D><I><R><L><D><C><D><S><D><V><V><L><L><K><V><T><Q><L><G><H><E><P><G><I><A><C><H><T><G><R><H><S><C... | Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.<BOP> | A1W445 |
Q0SN27 | RL23_BORAP | 50S ribosomal protein L23 | Borreliella | <M><K><A><Y><D><I><I><V><S><P><M><L><T><E><K><T><N><T><Q><R><E><S><I><N><V><Y><V><F><K><V><N><K><R><A><N><K><K><E><V><G><A><A><I><K><E><L><F><N><V><T><P><V><S><C><N><L><L><N><I><K><S><K><A><K><V><V><V><S><R><K><G><Y><P><I><G><K><G><K><T><S><S><W><K><K><A><Y><V><Y><L><K><K><E><D><K><I><D><I><F> | One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP> | Q0SN27 |
O52338 | RS3_MYCGA | 30S ribosomal protein S3 | Mycoplasma | <M><G><Q><K><V><N><S><N><G><L><R><F><G><I><N><K><N><W><Q><S><R><W><V><A><K><T><N><Q><Q><T><G><D><W><I><V><Q><D><E><K><I><R><N><Y><L><F><K><K><F><H><S><A><F><I><S><N><V><D><I><E><R><T><Q><T><S><I><R><V><F><I><Y><A><S><Q><P><G><I><I><L><G><K><E><A><A><N><I><K><V><I><L><L><A><I><N><K><I><V><G><R><H><I><K><V><D><V><D><V><L... | Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP> | O52338 |
Q830Y9 | NADE_ENTFA | NH(3)-dependent NAD(+) synthetase | Enterococcus | <M><T><T><L><Q><E><K><I><I><Q><E><L><G><V><L><P><T><I><D><P><K><E><E><V><R><K><S><I><D><F><L><K><A><Y><L><T><K><H><P><F><L><K><T><F><V><L><G><I><S><G><G><Q><D><S><T><L><A><G><R><L><A><Q><L><A><M><T><E><M><R><E><E><T><G><D><M><S><Y><Q><F><I><A><I><R><L><P><Y><G><E><Q><A><D><E><A><D><A><Q><A><A><L><A><F><I><Q><P><D><V><S... | Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.<BOP> | Q830Y9 |
P53685 | HST1_YEAST | Regulatory protein SIR2 homolog 1 | Saccharomyces | <M><N><I><L><L><M><Q><R><I><V><S><F><I><L><V><V><S><Q><G><R><Y><F><H><V><G><E><L><T><M><T><M><L><K><R><P><Q><E><E><E><S><D><N><N><A><T><K><K><L><K><T><R><L><T><Y><P><C><I><L><G><K><D><K><V><T><G><K><F><I><F><P><A><I><T><K><D><D><V><M><N><A><R><L><F><L><K><D><N><D><L><K><T><F><L><E><Y><F><L><P><V><E><V><N><S><I><Y><I><Y... | NAD-dependent histone deacetylase involved in telomeric silencing. Histone deacetylase proteins act via the formation of large multiprotein complexes that are responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epi... | P53685 |
Q7NGL0 | RF3_GLOVI | Peptide chain release factor 3 | Gloeobacter | <M><S><N><P><T><L><A><A><E><V><G><R><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><L><T><E><K><L><L><L><Y><G><G><A><I><D><M><A><G><S><V><R><A><R><R><N><Q><R><H><A><T><S><D><W><M><A><M><E><Q><Q><R><G><I><S><I><T><S><T><V><L><Q><F><V><Y><R><D><C><Q><I><N><L><L><D><T><P><G><H><Q><D><F><S><E><D><T><Y><R><T><L><A><A><A><D... | Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP> | Q7NGL0 |
A9MFE4 | CEDA_SALAR | Cell division activator CedA | Salmonella | <M><M><K><P><L><R><Q><Q><N><R><Q><I><I><S><Y><I><P><R><V><E><P><A><P><P><E><H><A><I><K><M><D><A><F><R><D><V><W><I><L><R><G><K><Y><V><A><F><V><L><M><G><E><S><F><Q><R><S><P><A><F><S><V><P><E><S><A><Q><R><W><A><N><Q><V><R><Q><E><N><E><I><A><D> | Activates the cell division inhibited by chromosomal DNA over-replication.<BOP> | A9MFE4 |
Q6MCT6 | RISB_PARUW | 6,7-dimethyl-8-ribityllumazine synthase | Candidatus Protochlamydia | <M><K><E><Y><K><G><K><L><N><I><S><K><A><R><I><G><I><V><I><S><R><F><N><E><T><I><T><K><N><L><L><E><G><S><L><D><E><L><E><R><Y><G><I><S><T><Q><N><L><P><V><A><W><V><P><G><A><F><E><I><P><L><I><A><K><Q><M><A><L><S><G><E><F><D><A><I><I><C><L><G><A><I><I><R><G><T><T><P><H><F><D><Y><V><A><S><Q><S><A><A><G><I><L><N><V><S><L><E><I... | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP> | Q6MCT6 |
Q00873 | CYT2_YEAST | Cytochrome c1 heme lyase | Saccharomyces | <M><M><S><S><D><Q><Q><G><K><C><P><V><D><E><E><T><K><K><L><W><L><R><E><H><G><N><E><A><H><P><G><A><T><A><P><G><N><Q><L><E><C><S><A><N><P><Q><D><N><D><K><T><P><E><Y><H><T><T><V><D><L><S><Q><S><R><E><V><S><T><I><P><R><T><N><S><D><R><N><W><I><Y><P><S><E><K><Q><F><Y><E><A><M><M><K><K><N><W><D><P><N><S><D><D><M><K><V><V><V><P... | Lyase that catalyzes the covalent linking of the heme group to the cytochrome C1 apoprotein to produce the mature functional cytochrome.<BOP> | Q00873 |
A8A4U6 | KBAZ_ECOHS | D-tagatose-1,6-bisphosphate aldolase subunit KbaZ | Escherichia | <M><K><H><L><T><E><M><V><R><Q><H><K><A><G><K><T><N><A><I><Y><A><V><C><S><A><H><P><L><V><L><E><A><A><I><R><Y><A><S><A><N><Q><T><P><L><L><I><E><A><T><S><N><Q><V><D><Q><F><G><G><Y><T><G><M><T><P><A><D><F><R><G><F><V><C><Q><L><A><D><S><L><N><F><P><Q><D><A><L><I><L><G><G><D><H><L><G><P><N><R><W><Q><N><L><P><A><A><Q><A><M><A... | Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity.<BOP> | A8A4U6 |
Q8ECV2 | TRPD_SHEON | Anthranilate phosphoribosyltransferase | Shewanella | <M><S><E><T><S><I><Q><P><L><L><D><I><L><F><Q><G><K><A><L><T><R><E><Q><T><A><S><L><F><S><V><L><I><Q><G><E><M><N><E><T><V><M><A><G><M><L><M><A><L><K><I><R><G><E><T><I><E><E><I><S><G><A><A><D><A><M><R><A><A><A><K><P><F><P><Y><P><E><S><S><R><S><Q><G><V><I><D><I><V><G><T><G><G><D><G><F><N><T><I><N><I><S><T><T><A><A><F><V><A... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q8ECV2 |
A0RQM9 | RIMO_CAMFF | Ribosome maturation factor RimO | Campylobacter | <M><P><N><L><Y><L><V><S><L><G><C><N><K><N><L><V><D><S><E><I><M><L><G><R><L><S><S><Y><N><I><V><D><K><P><N><N><A><D><V><M><I><V><N><T><C><G><F><I><E><S><A><K><E><E><S><V><R><T><I><L><E><L><A><S><Y><K><K><E><N><S><V><L><V><V><T><G><C><L><M><Q><R><Y><R><D><E><L><M><K><E><L><P><E><V><D><I><F><T><G><V><G><D><Y><A><S><I><D><E... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP> | A0RQM9 |
Q3KI09 | Y854_PSEPF | Nucleotide-binding protein Pfl01_0854 | Pseudomonas | <M><R><L><I><I><V><S><G><R><S><G><S><G><K><S><T><A><L><D><V><L><E><D><N><G><Y><Y><C><I><D><N><L><P><A><G><L><L><P><E><L><A><E><R><A><L><I><H><T><E><L><A><Q><P><L><V><A><V><S><I><D><A><R><N><L><P><S><H><L><S><R><F><P><E><L><L><E><D><V><R><A><K><H><I><Q><C><D><V><L><Y><L><D><A><D><E><E><T><L><L><K><R><F><S><E><T><R><R><R... | Displays ATPase and GTPase activities.<BOP> | Q3KI09 |
Q8J0N2 | SODC_CORMI | Superoxide dismutase [Cu-Zn] | Cordyceps | <M><V><K><A><V><C><V><L><R><G><D><A><K><V><A><G><T><V><T><F><E><Q><E><S><E><S><A><P><T><T><I><T><W><D><I><T><G><N><D><P><N><A><E><R><G><F><H><I><H><T><F><G><D><N><T><N><G><C><T><S><A><G><P><H><F><N><P><H><G><K><T><H><G><A><P><T><D><A><A><R><H><V><G><D><L><G><N><I><K><T><D><G><Q><G><N><A><K><G><S><V><Q><D><S><H><V><K><L... | Destroys radicals which are normally produced within the cells and which are toxic to biological systems.<BOP> | Q8J0N2 |
B7LN84 | MUKF_ESCF3 | Chromosome partition protein MukF | Escherichia | <M><S><E><F><S><Q><T><V><P><E><L><V><A><W><A><R><K><N><D><F><S><I><S><L><P><V><D><R><L><S><F><L><L><A><V><A><T><L><N><G><E><R><L><D><G><E><M><S><E><G><E><L><V><D><A><F><R><H><V><S><D><A><F><E><Q><T><S><E><T><I><G><V><R><A><N><N><A><I><N><D><M><V><R><Q><R><L><L><N><R><F><T><S><E><Q><A><E><G><N><A><I><Y><R><L><T><P><L><G... | Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and Muk... | B7LN84 |
B4LUA5 | EIF3I_DROVI | TRIP-1 homolog | Drosophila | <M><L><Q><G><H><E><R><S><I><T><Q><I><K><Y><N><R><E><G><D><L><L><F><S><S><S><K><D><Q><K><P><N><V><W><Y><S><L><N><G><E><R><L><G><T><Y><D><G><H><Q><G><A><V><W><C><L><D><V><D><W><E><S><R><K><L><I><T><G><A><G><D><M><T><T><K><I><W><D><V><E><Y><G><T><V><I><A><S><I><P><T><K><S><S><V><R><T><S><N><F><S><F><S><G><N><Q><A><A><Y><S... | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t... | B4LUA5 |
Q39785 | CHI2_GOSHI | Endochitinase 2 | Gossypium | <E><Q><C><G><R><Q><A><G><G><A><L><C><P><G><G><L><C><C><S><Q><F><G><W><C><G><S><T><A><D><Y><C><T><V><P><G><C><Q><S><Q><C><S><G><S><G><P><A><P><G><P><G><G><L><T><N><L><I><S><R><E><T><F><N><Q><M><L><L><H><R><N><D><G><A><C><P><A><R><G><F><Y><T><Y><D><A><F><I><A><A><A><R><S><F><P><A><F><A><T><T><G><D><Q><A><T><R><K><R><E><I... | Defense against chitin-containing fungal pathogens.<BOP> | Q39785 |
Q61754 | K1B24_MOUSE | Tissue kallikrein 24 | null | <M><W><F><L><I><L><F><L><A><L><S><L><G><G><I><D><A><A><P><P><V><Q><S><R><V><V><G><G><F><K><C><E><K><N><S><Q><P><W><H><V><A><V><F><R><Y><N><K><Y><I><C><G><G><V><L><L><N><P><N><W><V><L><T><A><A><H><C><Y><G><N><A><T><S><Q><Y><N><V><W><L><G><K><N><K><L><F><Q><R><E><P><S><A><Q><H><R><W><V><S><K><S><F><P><H><P><D><Y><N><M><S... | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.<BOP> | Q61754 |
P57314 | MRAY_BUCAI | UDP-MurNAc-pentapeptide phosphotransferase | Buchnera | <M><L><I><F><F><N><K><Y><L><H><I><N><L><N><I><L><S><Y><I><P><Y><R><A><I><F><S><L><L><T><S><F><F><I><N><L><Y><I><G><P><Y><F><I><Y><Y><F><K><K><L><Q><T><Y><Q><I><I><R><N><N><G><P><K><T><H><Y><S><K><K><N><T><P><T><M><G><G><I><F><I><I><F><S><I><L><F><S><T><I><L><Y><C><N><L><S><N><I><Y><I><W><Y><V><I><S><I><L><I><G><Y><G><L... | Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I... | P57314 |
A6RC73 | NOP16_AJECN | Nucleolar protein 16 | unclassified Histoplasma | <M><G><R><I><L><Q><K><K><K><N><R><S><G><A><P><R><V><K><Q><K><S><N><R><L><K><N><G><N><K><K><I><N><V><L><G><N><A><I><I><A><Q><N><W><D><K><K><L><T><L><T><Q><N><Y><R><R><L><G><L><A><S><Q><L><N><A><P><T><G><G><A><E><N><K><P><D><D><P><S><N><G><R><Q><E><A><D><S><L><H><L><L><P><S><L><A><S><V><K><M><I><K><P><A><E><M><R><V><E><R... | Involved in the biogenesis of the 60S ribosomal subunit.<BOP> | A6RC73 |
Q9I4P4 | FLGJ_PSEAE | Muramidase FlgJ | Pseudomonas | <M><D><S><R><L><L><S><G><I><G><A><G><P><D><S><G><S><Y><T><D><L><N><R><L><N><Q><L><K><V><G><K><D><R><D><G><E><A><N><I><R><K><V><A><Q><E><F><E><S><L><F><L><N><E><M><L><K><S><M><R><S><A><N><E><A><L><G><D><G><N><F><M><N><S><Q><T><T><K><Q><Y><Q><D><M><Y><D><Q><Q><L><S><V><S><L><S><K><N><A><G><G><I><G><L><A><D><V><L><V><R><Q... | Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.<BOP> | Q9I4P4 |
Q1GCM3 | NTPP_RUEST | Nucleotide pyrophosphatase | unclassified Ruegeria | <M><S><T><H><I><L><L><A><S><G><S><E><I><R><A><K><L><L><R><Q><A><G><V><D><F><R><V><E><V><A><R><V><D><E><D><A><I><K><T><A><L><E><A><D><G><A><S><P><R><D><I><A><D><T><L><A><E><A><K><A><R><K><V><S><G><K><F><P><E><E><M><V><L><G><C><D><Q><V><L><D><F><E><G><T><L><L><S><K><P><K><D><K><N><Q><A><L><Q><Q><L><K><A><M><R><G><K><R><H... | Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP> | Q1GCM3 |
A1SMA5 | DNLJ_NOCSJ | Polydeoxyribonucleotide synthase [NAD(+)] | Nocardioides | <M><K><R><N><G><F><V><P><S><N><S><V><G><R><R><G><I><P><S><N><S><T><S><S><A><I><A><S><A><G><G><A><V><V><W><T><G><A><G><A><G><R><V><R><A><R><P><E><Q><V><S><V><G><P><G><T><M><S><C><V><T><D><P><R><E><E><H><R><L><I><A><E><E><I><E><E><A><R><W><R><Y><Y><V><L><D><S><P><T><I><D><D><A><D><F><D><R><R><M><R><R><L><E><A><L><E><E><E... | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP> | A1SMA5 |
Q9FHZ1 | SCL23_ARATH | GRAS family protein 28 | Arabidopsis | <M><T><T><K><R><I><D><R><D><L><P><S><S><D><D><P><S><S><A><K><R><R><I><E><F><P><E><E><T><L><E><N><D><G><A><A><A><I><K><L><L><S><L><L><L><Q><C><A><E><Y><V><A><T><D><H><L><R><E><A><S><T><L><L><S><E><I><S><E><I><C><S><P><F><G><S><S><P><E><R><V><V><A><Y><F><A><Q><A><L><Q><T><R><V><I><S><S><Y><L><S><G><A><C><S><P><L><S><E><K... | Probable transcription factor involved in plant development.<BOP> | Q9FHZ1 |
A8F8L8 | DAPH_PSELT | Tetrahydrodipicolinate N-acetyltransferase | Pseudothermotoga | <M><N><N><D><L><T><A><D><S><I><I><E><M><I><S><S><S><K><K><K><T><P><V><I><A><Y><V><K><G><H><L><S><D><I><D><M><S><G><V><Q><F><F><G><T><D><N><F><G><I><I><F><A><D><Y><E><D><L><R><Q><F><L><E><K><N><G><N><K><I><H><D><V><H><I><E><A><K><A><R><N><S><A><L><P><M><A><D><I><T><K><F><N><A><R><V><E><P><G><A><V><I><R><D><L><V><K><I><G... | Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.<BOP> | A8F8L8 |
Q9L4U5 | AKNT_STRGJ | Protein AknT | Streptomyces | <M><Q><T><Q><N><A><P><E><T><A><E><N><Q><Q><T><D><S><E><L><G><R><H><L><L><T><A><R><G><F><H><W><I><Y><G><T><S><G><D><P><Y><A><L><T><L><R><A><E><S><D><D><P><A><L><L><T><R><R><I><R><E><A><G><T><P><L><W><Q><S><T><T><G><A><W><V><T><G><R><H><G><V><A><A><E><A><L><A><D><P><R><L><A><L><R><H><A><D><L><P><G><P><Q><R><H><V><F><S><D... | Involved in the biosynthesis of the anthracycline antitumor agent aclacinomycin A. AknT is required for the glycosylation of aklavinone aglycone by AknS to yield aclacinomycin T (rhodosaminyl-aklavinone).<BOP> | Q9L4U5 |
B8CX03 | MTAD_HALOH | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | Halothermothrix | <M><K><I><L><I><K><N><V><D><V><I><Y><T><A><D><S><N><R><S><I><I><K><N><G><Y><I><I><I><Q><D><N><K><I><K><E><I><N><D><M><D><N><L><V><Y><Q><S><N><D><F><D><D><V><I><S><G><K><G><K><M><A><L><P><G><L><V><N><A><H><T><H><S><A><M><T><L><L><R><G><F><A><D><D><M><P><L><H><K><W><L><Q><E><K><I><W><P><F><E><K><T><L><I><P><E><D><I><Y><W... | Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.<BOP> | B8CX03 |
B5XRA3 | MDCG_KLEP3 | Malonate decarboxylase holo-[acyl-carrier-protein] synthase | Klebsiella | <M><S><S><T><P><R><P><H><D><L><V><W><L><N><H><A><S><A><L><E><A><I><A><E><P><W><V><A><Q><Q><W><R><A><A><L><P><V><V><V><R><R><D><V><D><D><Q><A><R><I><P><V><G><V><R><G><M><K><R><E><Q><R><A><A><G><W><V><Q><A><H><N><I><V><R><C><V><T><P><E><M><L><V><E><R><E><R><L><L><G><S><P><F><V><S><Q><P><P><V><Q><A><A><I><A><L><T><L><H><P... | Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].<BOP> | B5XRA3 |
Q02K17 | RECR_PSEAB | Recombination protein RecR | Pseudomonas | <M><S><F><S><P><L><I><R><Q><L><I><E><S><L><R><I><L><P><G><V><G><Q><K><S><A><Q><R><M><A><L><M><L><L><E><R><D><R><S><G><G><L><K><L><A><Q><A><L><T><A><A><M><E><G><V><G><H><C><R><R><C><R><T><L><S><E><E><E><L><C><P><Q><C><A><D><P><R><R><D><D><S><L><L><C><V><V><E><G><P><L><D><V><F><A><V><E><Q><T><G><Y><R><G><R><Y><F><V><L><K... | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.<BOP> | Q02K17 |
Q7U317 | CH60_HELHP | Chaperonin-60 | Helicobacter | <M><A><S><K><E><I><N><F><S><D><S><A><R><N><K><L><Y><E><G><I><K><Q><L><S><D><A><V><K><V><T><M><G><P><K><G><R><N><V><L><I><Q><K><S><Y><G><A><P><T><I><T><K><D><G><V><S><V><A><K><E><I><E><L><A><D><P><I><A><N><M><G><A><Q><L><V><K><E><V><A><S><K><T><A><D><A><A><G><D><G><T><T><T><A><T><V><L><A><Y><S><I><Y><K><E><G><L><R><N><I... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q7U317 |
A5IEA1 | AROC_LEGPC | 5-enolpyruvylshikimate-3-phosphate phospholyase | Legionella | <M><S><G><N><T><F><G><A><L><F><T><V><T><T><F><G><E><S><H><G><P><A><I><G><C><V><V><D><G><C><P><P><G><M><S><L><T><E><A><D><I><Q><P><F><L><D><K><R><K><P><G><Q><S><K><Y><T><T><Q><R><R><E><E><D><K><V><Q><I><L><S><G><V><F><D><G><K><T><T><G><A><P><I><A><L><L><I><Q><N><T><D><Q><R><S><R><D><Y><E><D><I><K><N><L><F><R><P><G><H><A... | Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s... | A5IEA1 |
Q01882 | RAG2_ORYSJ | Seed allergenic protein RA14 | Oryza sativa | <M><A><S><N><K><V><V><F><S><A><L><L><L><I><I><V><S><V><L><A><A><T><A><T><M><A><D><H><H><K><D><Q><V><V><Y><S><L><G><E><R><C><Q><P><G><M><G><Y><P><M><Y><S><L><P><R><C><R><A><V><V><K><R><Q><C><V><G><H><G><A><P><G><G><A><V><D><E><Q><L><R><Q><D><C><C><R><Q><L><A><A><V><D><D><S><W><C><R><C><S><A><L><N><H><M><V><G><G><I><Y><R... | Seed storage protein.<BOP> | Q01882 |
Q9SCX9 | GPDA1_ARATH | Glycerol-3-phosphate dehydrogenase [NAD(+)] 1, chloroplastic | Arabidopsis | <M><R><F><R><S><F><F><F><S><S><S><I><F><S><L><S><H><S><R><S><P><S><L><S><S><S><R><F><S><S><L><S><A><A><M><S><P><A><L><E><K><S><R><Q><G><N><G><G><C><N><D><D><S><K><S><K><V><T><V><V><G><S><G><N><W><G><S><V><A><A><K><L><I><A><S><N><A><L><K><L><P><S><F><H><D><E><V><R><M><W><V><F><E><E><V><L><P><N><G><E><K><L><N><D><V><I><N... | Involved in glycerolipid metabolism.<BOP> | Q9SCX9 |
B0KA56 | YBEY_THEP3 | Endoribonuclease YbeY | Thermoanaerobacter | <M><N><I><L><I><D><N><R><Q><D><K><V><D><A><I><N><L><E><E><L><V><E><K><V><I><K><T><V><L><E><V><E><E><V><I><D><N><V><E><V><S><V><S><F><V><D><N><E><E><I><R><K><L><N><K><Y><Y><R><G><I><D><K><P><T><D><V><L><S><F><P><L><A><E><F><E><D><T><Y><G><E><V><E><E><I><E><E><D><S><E><E><V><Q><P><I><G><D><I><V><I><S><L><E><K><A><L><E><Q... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | B0KA56 |
B0K682 | HPRK_THEPX | HPr(Ser) kinase/phosphorylase | unclassified Thermoanaerobacter | <M><D><K><I><P><V><E><T><L><I><K><D><L><N><L><E><V><I><V><E><A><K><N><N><K><I><D><I><T><T><S><D><V><N><R><P><G><L><Q><F><S><G><F><Y><E><H><F><A><Y><E><R><V><Q><I><I><G><K><V><E><T><T><F><I><E><Q><L><P><D><D><V><L><A><E><R><A><D><R><F><F><N><Y><P><I><P><C><L><I><V><T><R><D><L><N><I><R><Q><E><I><I><D><A><A><Q><K><H><D><R... | Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphor... | B0K682 |
Q254T8 | GUAA_CHLFF | Glutamine amidotransferase | Chlamydia | <M><S><K><I><L><I><L><D><F><G><S><Q><Y><T><N><V><L><A><K><K><I><R><L><L><S><V><F><C><E><V><L><P><W><N><T><P><L><E><D><I><L><Q><E><S><P><S><G><L><I><F><S><G><G><P><H><S><V><Y><Q><E><N><S><P><K><V><D><R><E><I><Y><N><A><N><I><P><I><L><G><V><C><Y><G><M><Q><L><I><A><R><D><F><G><S><E><V><R><G><G><E><N><E><F><G><Y><T><P><I><V... | Catalyzes the synthesis of GMP from XMP.<BOP> | Q254T8 |
Q6ME71 | FMT_PARUW | Methionyl-tRNA formyltransferase | Candidatus Protochlamydia | <M><R><N><R><K><M><K><V><I><F><F><G><T><P><L><F><A><A><Q><V><L><E><F><L><L><Q><N><Q><V><E><V><V><A><V><I><S><K><P><D><R><P><K><G><R><S><S><I><P><V><P><T><P><V><K><L><I><A><Q><S><Y><H><L><P><L><Y><Q><P><E><V><V><S><S><L><D><F><A><P><V><L><K><N><Y><E><A><D><L><F><V><V><V><A><Y><G><E><I><I><K><Q><H><L><L><D><M><P><K><R><A... | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP> | Q6ME71 |
Q6EVZ5 | NU1C_NYMAL | NADH-plastoquinone oxidoreductase subunit 1 | Nymphaea | <M><I><I><E><E><A><Q><A><I><N><S><F><F><R><S><E><S><S><K><E><V><Y><G><L><I><W><L><L><V><P><I><L><T><L><V><L><G><I><T><I><G><V><L><V><I><V><W><L><E><R><K><I><S><A><G><I><Q><R><R><I><G><P><E><Y><A><G><P><L><G><I><L><Q><A><L><A><D><G><V><K><L><L><F><K><E><D><L><L><P><S><R><G><D><I><R><L><F><S><V><G><P><S><V><A><V><V><S><I... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | Q6EVZ5 |
Q8MTX2 | NDB42_OPIMA | Cytotoxic linear peptide IsCT2f | Opisthacanthus | <M><K><T><Q><F><A><I><L><L><V><A><L><V><L><F><Q><M><F><A><Q><S><E><A><I><F><G><A><I><W><N><G><I><K><S><L><F><G><R><R><A><L><N><N><D><L><D><L><D><G><L><D><E><L><F><D><G><E><I><S><Q><A><D><V><D><F><L><K><E><L><M><R> | IsCT2f shows neither hemolytic, nor antibacterial activities, surely due to the fact that it cannot apply amphipathic alpha-helical structure.<BOP> | Q8MTX2 |
Q08H50 | NU4LM_PHOFA | NADH dehydrogenase subunit 4L | Phoca | <M><S><M><V><Y><A><N><I><F><L><A><F><I><M><S><L><M><G><L><L><M><Y><R><S><H><L><M><S><S><L><L><C><L><E><G><M><M><L><S><L><F><V><M><M><T><V><T><I><L><N><N><H><F><T><L><A><N><M><A><P><I><I><L><L><V><F><A><A><C><E><A><A><L><G><L><S><L><L><V><M><V><S><N><T><Y><G><T><D><Y><V><Q><N><L><N><L><L><Q><C> | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.<BOP> | Q08H50 |
P60973 | LGT_RHOPA | Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase | Rhodopseudomonas | <M><P><F><F><A><V><A><F><P><V><F><D><P><V><A><V><A><I><G><P><F><A><I><R><W><Y><A><L><A><Y><I><A><G><I><V><I><G><W><L><Y><A><R><M><L><L><Q><R><Q><R><L><W><G><G><P><S><P><I><S><L><E><A><F><D><D><F><I><L><W><V><T><I><G><I><I><L><G><G><R><T><G><Y><V><L><F><Y><N><L><D><F><F><I><R><H><P><A><E><I><F><E><L><W><K><G><G><M><S><F... | Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP> | P60973 |
Q2NAK3 | RSMI_ERYLH | rRNA (cytidine-2'-O-)-methyltransferase RsmI | Erythrobacter | <M><Q><H><D><H><S><A><E><P><L><S><P><G><L><Y><I><V><A><T><P><I><G><N><L><G><D><I><T><L><R><A><I><E><T><L><R><R><C><D><A><V><A><C><E><D><T><R><M><T><G><K><L><L><K><H><L><G><I><S><K><S><L><W><R><Y><D><D><H><S><D><A><K><A><R><E><K><I><V><A><A><I><S><E><K><A><V><A><L><V><S><D><A><G><T><P><L><I><S><D><P><G><Y><R><L><V><R><D... | Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.<BOP> | Q2NAK3 |
Q9D291 | DESI2_MOUSE | Protein FAM152A | Mus | <M><G><A><N><Q><L><V><V><L><N><V><Y><D><M><Y><W><M><N><E><Y><T><S><S><I><G><I><G><V><F><H><S><G><I><E><V><Y><G><R><E><F><A><Y><G><G><H><P><Y><P><F><S><G><I><F><E><I><S><P><G><N><A><S><E><L><G><E><T><F><K><F><K><E><A><V><V><L><G><S><T><D><F><L><E><D><D><I><E><K><I><V><E><E><L><G><K><E><Y><K><G><N><A><Y><H><L><M><H><K><N... | Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization.<BOP> | Q9D291 |
Q2QQ99 | SP1L3_ORYSJ | Protein SPIRAL1-like 3 | Oryza sativa | <M><G><R><G><V><S><S><G><G><G><Q><S><S><L><G><Y><L><F><G><G><G><E><A><P><K><S><A><E><K><P><A><P><V><Q><K><P><A><P><S><S><S><A><E><K><L><K><E><I><P><A><G><I><Q><S><S><K><A><N><N><Y><M><R><A><E><G><Q><N><C><G><N><F><L><T><D><R><P><S><T><K><V><Q><A><A><P><G><G><G><S><S><L><D><Y><L><F><S><G><N><K><D><G><K> | Acts in maintaining the cortical microtubules organization essential for anisotropic cell growth.<BOP> | Q2QQ99 |
Q493C8 | DXR_BLOPB | 2-C-methyl-D-erythritol 4-phosphate synthase | Candidatus Blochmannia | <M><Q><S><L><T><I><L><G><S><T><G><S><I><G><K><A><T><L><S><V><I><Q><Q><H><T><D><K><F><F><V><H><A><L><V><A><K><N><N><V><A><I><M><T><E><Q><C><I><A><M><S><P><K><Y><A><C><M><I><S><E><D><A><A><R><I><L><K><K><N><L><I><T><A><G><K><Y><D><I><E><V><L><S><G><V><M><H><A><C><E><L><A><S><T><N><D><V><D><M><V><M><S><A><I><V><G><I><A><G... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP> | Q493C8 |
Q2IWG4 | TATB_RHOP2 | Sec-independent protein translocase protein TatB | Rhodopseudomonas | <M><F><D><I><G><W><S><E><L><V><V><I><G><V><V><A><L><V><A><I><G><P><K><E><L><P><G><V><L><R><M><V><G><Q><W><M><G><K><A><R><K><L><A><S><E><F><Q><G><Q><F><Q><E><A><M><R><E><A><E><M><A><D><L><K><K><S><F><D><E><V><K><E><A><T><A><G><L><S><T><N><N><M><L><T><K><L><G><S><E><L><S><E><A><A><A><I><D><K><S><A><L><D><S><P><P><V><E><P... | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that... | Q2IWG4 |
B2WMJ3 | MKAR_PYRTR | Microsomal beta-keto-reductase | Pyrenophora | <M><A><N><I><L><E><P><F><G><I><R><I><D><A><D><N><S><F><V><Q><A><A><V><T><G><F><L><L><V><G><I><A><S><F><A><A><P><L><I><S><T><I><R><V><L><L><S><L><F><V><L><P><G><K><S><L><T><T><F><G><P><R><G><T><W><A><L><I><T><G><A><S><D><G><I><G><K><E><F><A><L><S><L><A><A><K><G><Y><N><L><I><L><V><S><R><T><Q><S><K><L><D><S><L><S><A><D><I... | Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingol... | B2WMJ3 |
P0DPT4 | KAX47_TITST | T.sigmurus alpha-KTx | Tityus | <M><K><A><F><Y><G><I><L><I><I><F><I><L><I><S><M><L><D><L><S><Q><Q><V><F><I><N><A><K><C><R><G><S><P><E><C><L><P><K><C><K><E><A><I><G><K><A><A><G><K><C><M><N><G><K><C><K><C><Y><P> | Potently blocks Kv1.1/KCNA1 (85%), Kv1.2/KCNA2 (91%), Kv1.3/KCNA3 (89%), Kv1.6/KCNA6 (94%), and Shaker (97%).<BOP> | P0DPT4 |
B9WEC5 | RSSA_CANDC | 40S ribosomal protein S0 | Candida | <M><S><L><P><A><S><F><D><L><T><P><E><D><A><K><L><L><L><A><A><N><V><H><L><G><A><K><N><V><Q><V><H><N><K><P><Y><V><Y><K><T><R><P><D><G><M><N><I><I><N><I><G><K><T><W><E><K><I><V><L><A><A><R><I><I><A><A><V><P><N><A><S><D><V><A><V><C><S><S><R><T><F><G><Q><R><A><V><L><K><F><A><A><H><T><G><A><T><A><I><A><G><R><F><T><P><G><N><F... | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.<BOP> | B9WEC5 |
Q9EP95 | RETNA_MOUSE | RELMalpha | Mus | <M><K><T><T><T><C><S><L><L><I><C><I><S><L><L><Q><L><M><V><P><V><N><T><D><E><T><I><E><I><I><V><E><N><K><V><K><E><L><L><A><N><P><A><N><Y><P><S><T><V><T><K><T><L><S><C><T><S><V><K><T><M><N><R><W><A><S><C><P><A><G><M><T><A><T><G><C><A><C><G><F><A><C><G><S><W><E><I><Q><S><G><D><T><C><N><C><L><C><L><L><V><D><W><T><T><A><R><C... | Probable hormone. Plays a role in pulmonary vascular remodeling.<BOP> | Q9EP95 |
C3P3V9 | SELO_BACAA | Protein adenylyltransferase SelO | Bacillus cereus group | <M><T><K><N><N><E><A><G><W><N><L><D><H><S><Y><T><T><L><P><Q><S><F><Y><T><E><I><P><P><T><P><V><S><S><P><E><L><V><K><L><N><H><S><L><A><I><S><L><G><F><N><P><E><E><L><K><K><E><A><E><I><A><I><F><A><G><N><A><L><P><E><G><A><H><P><L><A><Q><A><Y><A><G><H><Q><F><G><H><F><N><M><L><G><D><G><R><A><L><L><I><G><E><Q><M><T><P><S><G><K... | Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).<BOP> | C3P3V9 |
Q4UUM0 | DER_XANC8 | GTP-binding protein EngA | Xanthomonas | <M><L><P><L><V><A><L><V><G><R><P><N><V><G><K><S><T><I><F><N><A><L><T><R><T><R><D><A><L><V><H><D><Q><P><G><V><T><R><D><R><N><Y><G><V><C><R><L><D><E><Q><Q><P><F><I><V><V><D><T><G><G><I><A><G><D><E><E><G><L><A><G><A><T><A><R><Q><A><R><A><A><A><G><E><A><D><L><V><L><F><V><V><D><G><R><E><G><A><S><S><L><D><D><E><I><L><A><W><L... | GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP> | Q4UUM0 |
B2HDI5 | ENO_MYCMM | 2-phosphoglycerate dehydratase | Mycobacterium | <M><P><I><I><E><Q><V><G><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><E><V><A><L><I><D><G><T><F><A><R><A><A><V><P><S><G><A><S><T><G><E><H><E><A><V><E><L><R><D><G><G><D><R><Y><G><G><K><G><V><K><K><A><V><E><A><V><L><D><E><I><G><P><A><V><I><G><L><N><A><D><D><Q><R><L><V><D><Q><A><L><V><D><L><D><G><T><P><D><K><S><R><L><G><G... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP> | B2HDI5 |
Q7NQF9 | RL16_CHRVO | 50S ribosomal protein L16 | Chromobacterium | <M><L><Q><P><T><R><L><K><Y><R><K><Q><H><K><G><R><N><T><G><I><A><T><R><G><N><K><V><S><F><G><D><F><G><L><K><A><I><G><R><G><R><L><T><A><R><Q><I><E><A><A><R><R><A><M><T><R><H><I><K><R><G><G><R><I><W><I><R><I><F><P><D><K><P><I><T><S><K><P><A><E><V><R><M><G><G><G><K><G><S><P><E><Y><Y><V><A><E><I><Q><P><G><K><M><L><Y><E><M><D... | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP> | Q7NQF9 |
P59463 | CYAY_BUCBP | Iron-sulfur cluster assembly protein CyaY | Buchnera | <M><K><K><N><N><S><N><P><L><K><I><N><E><Y><H><T><L><V><N><K><L><F><L><L><I><E><E><N><I><D><K><N><Q><E><K><C><D><I><D><C><E><L><H><H><N><M><L><I><I><N><L><N><N><T><N><Q><V><I><I><N><K><Q><E><S><L><K><Q><I><W><L><A><T><K><K><N><G><Y><H><F><E><Y><I><N><K><Q><W><I><C><N><R><T><K><K><D><F><W><N><V><L><Q><E><S><C><V><Y><Q><T... | Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.<BOP> | P59463 |
Q5HKB0 | COPB_STAEQ | Probable copper-transporting P-type ATPase B | Staphylococcus | <M><N><H><S><N><Q><M><H><H><D><N><H><E><S><H><N><H><H><S><G><H><A><H><H><H><G><N><F><K><V><K><F><F><V><S><L><I><F><A><I><P><I><I><L><L><S><P><L><M><G><V><N><L><P><F><Q><F><T><F><P><G><S><E><W><V><V><L><I><L><S><T><I><L><F><F><Y><G><G><K><P><F><L><S><G><G><K><D><E><I><A><T><K><K><P><G><M><M><T><L><V><A><L><G><I><S><V><A... | Involved in copper transport.<BOP> | Q5HKB0 |
Q0ID14 | RS17_SYNS3 | 30S ribosomal protein S17 | unclassified Synechococcus | <M><A><L><K><E><R><V><G><T><V><V><S><D><K><M><D><K><T><V><V><V><A><V><E><N><R><F><P><H><P><I><Y><Q><K><T><V><S><R><T><T><R><Y><K><A><H><D><E><D><N><A><C><R><V><G><D><R><V><R><I><T><E><T><R><P><L><S><R><H><K><R><W><A><I><A><E><V><L><S><Q><S><P><K><A><E><E><V><T><K> | One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP> | Q0ID14 |
Q5YQ76 | GLYA_NOCFA | Serine hydroxymethyltransferase | Nocardia | <M><T><Q><T><T><A><S><V><N><T><Q><S><L><G><E><L><D><P><E><L><A><A><A><M><A><G><E><L><A><R><E><R><D><T><L><E><M><I><A><S><E><N><F><V><P><R><A><V><L><Q><A><Q><G><S><V><L><T><N><K><Y><A><E><G><Y><P><G><R><R><Y><Y><G><G><C><E><N><V><D><V><V><E><N><L><A><R><E><R><A><K><E><L><F><G><A><E><F><A><N><V><Q><P><H><S><G><A><Q><A><N... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | Q5YQ76 |
Q9ZMA9 | ILVC_HELPJ | Ketol-acid reductoisomerase type I | Helicobacter | <M><A><L><P><V><Y><Y><D><K><D><I><D><L><G><V><I><Q><S><L><Q><V><G><I><I><G><Y><G><V><Q><G><E><A><Q><A><L><N><L><R><D><S><K><V><K><V><R><I><G><L><Y><Q><G><S><L><S><V><S><K><A><K><K><E><G><F><E><V><L><G><V><K><E><L><V><Q><Q><S><D><V><I><M><A><L><L><P><D><E><L><H><K><E><V><L><E><K><E><V><I><P><F><L><K><E><G><Q><I><I><G><F... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | Q9ZMA9 |
P46914 | COTS_BACSU | Coat protein 40 kDa component 2 | Bacillus | <M><Y><Q><K><E><H><E><E><Q><I><V><S><E><I><L><S><Y><Y><P><F><H><I><D><H><V><A><L><K><S><N><K><S><G><R><K><I><W><E><V><E><T><D><H><G><P><K><L><L><K><E><A><Q><M><K><P><E><R><M><L><F><I><T><Q><A><H><A><H><L><Q><E><K><G><L><P><I><A><P><I><H><Q><T><K><N><G><G><S><C><L><G><T><D><Q><V><S><Y><S><L><Y><D><K><V><T><G><K><E><M><I... | Seems to be required for the assembly of the CotSA protein in spores.<BOP> | P46914 |
B0U7Z5 | TRPD_METS4 | Anthranilate phosphoribosyltransferase | Methylobacterium | <M><D><S><F><K><P><Y><L><A><K><V><A><T><G><A><A><L><T><R><E><E><A><R><T><A><F><D><H><L><L><S><G><E><V><T><H><A><Q><A><G><A><F><L><M><A><L><R><V><R><G><E><A><Q><D><E><I><V><G><A><A><G><A><L><R><E><R><M><V><R><V><V><A><P><A><G><A><I><D><I><V><G><T><G><G><D><H><S><G><S><Y><N><V><S><T><L><A><S><I><L><T><A><A><C><G><V><P><V... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | B0U7Z5 |
C0HLV9 | MP31_MOUSE | Micropeptide 31 | Mus | <M><W><R><D><S><L><C><T><A><A><G><Y><A><L><G><R><R><D><A><A><A><L><S><S><L><L><S><E><A><A><A><M><M><E><V> | Inhibits lactate dehydrogenase (LDH)-mediated conversion of lactate to pyruvate in mitochondria by competing with mitochondrial LDH for binding to NAD(+). Also inhibits cellular lactate utilization.<BOP> | C0HLV9 |
A4TE84 | RNH2_MYCGI | Ribonuclease HII | Mycolicibacterium | <M><P><A><V><W><P><P><R><T><V><I><R><K><S><S><G><L><R><T><L><E><S><A><L><Y><R><A><G><L><G><P><V><A><G><V><D><E><V><G><R><G><A><C><A><G><P><L><V><V><A><A><C><I><L><G><P><N><R><L><E><S><L><S><A><L><D><D><S><K><K><L><N><E><S><E><R><E><R><L><F><P><L><I><R><R><Y><A><V><A><F><H><V><V><F><I><P><S><V><E><V><D><R><R><G><V><H><V... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | A4TE84 |
A9KQ75 | GAHP1_LACP7 | D-galactosyl-1,4-L-rhamnose phosphorylase | Lachnospiraceae | <M><S><E><K><L><T><G><R><V><T><V><P><T><D><V><D><M><I><Q><E><T><K><E><I><A><E><R><W><G><A><D><A><L><R><D><C><D><G><T><D><M><P><D><E><L><K><K><M><P><A><K><I><Y><S><T><Y><Y><T><T><R><K><D><N><A><W><A><N><A><N><P><D><E><V><Q><Q><V><Y><L><M><T><E><F><Y><T><A><M><S><Q><G><E><L><R><I><P><L><M><K><H><L><Y><K><D><Q><L><K><P><N... | Reversibly phosphorolyzes beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine to form alpha-D-galactopyranose 1-phosphate and acetyl-D-glucosamine. Active towards galacto-N-biose and lacto-N-biose. Does not phosphorolyze galacto-N-tetraose or lacto-N-tetraose. In the reverse reaction has activity toward N-acetyl-D-gl... | A9KQ75 |
A9KU74 | RECF_SHEB9 | DNA replication and repair protein RecF | Shewanella | <M><S><L><T><R><L><N><I><E><A><F><R><N><I><Q><S><A><Q><L><I><P><A><P><G><I><N><L><I><Y><G><Q><N><G><S><G><K><T><S><I><L><E><A><I><Y><F><L><G><M><G><R><S><F><R><S><H><L><S><Q><R><V><I><N><N><D><D><D><K><L><T><L><F><A><T><L><N><L><A><R><G><D><S><K><I><G><L><R><R><F><R><S><G><E><T><E><V><R><I><D><G><E><K><V><K><R><L><S><T... | The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.<BOP> | A9KU74 |
P00847 | ATP6_BOVIN | F-ATPase protein 6 | Bos | <M><N><E><N><L><F><T><S><F><I><T><P><V><I><L><G><L><P><L><V><T><L><I><V><L><F><P><S><L><L><F><P><T><S><N><R><L><V><S><N><R><F><V><T><L><Q><Q><W><M><L><Q><L><V><S><K><Q><M><M><S><I><H><N><S><K><G><Q><T><W><T><L><M><L><M><S><L><I><L><F><I><G><S><T><N><L><L><G><L><L><P><H><S><F><T><P><T><T><Q><L><S><M><N><L><G><M><A><I><P... | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca... | P00847 |
P83658 | DIDS_ECHCA | Disintegrin schistatin | Echis | <N><S><V><H><P><C><C><D><P><V><I><C><E><P><R><E><G><E><H><C><I><S><G><P><C><C><E><N><C><Y><F><L><N><S><G><T><I><C><K><R><A><R><G><D><G><N><Q><D><Y><C><T><G><I><T><P><D><C><P><R><N><R><Y><N><V> | May bind to both alpha-IIb/beta-3 (ITGA2B/ITGB3) and alpha-V/beta-3 (ITGAV/ITGB3) integrins, and may inhibit platelet aggregation.<BOP> | P83658 |
B1P1G1 | JZ38D_CHIGU | Peptide F4-25.19 | Chilobrachys | <M><K><V><S><V><L><I><T><L><A><V><L><G><V><M><F><L><L><T><S><A><E><E><R><G><S><D><Q><M><D><S><P><A><W><L><K><S><M><E><I><I><F><Q><S><E><E><R><E><C><R><W><L><F><G><G><C><E><K><D><S><D><C><C><E><H><L><G><C><R><R><A><K><P><S><W><C><G><W><D><F><T><V><G><K><W><E><M><L><I><N><M><N><I><F><R><I><V><F><S><Y><S><M><C><T><V> | Probable ion channel inhibitor.<BOP> | B1P1G1 |
Q8DI68 | ACSF2_THEVB | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 | Thermosynechococcus | <M><V><A><I><A><P><N><P><H><S><G><Q><S><V><K><T><I><R><E><N><L><L><T><P><R><F><Y><T><T><D><F><E><Q><A><A><K><L><D><L><S><R><Q><Q><E><Q><L><E><A><M><L><A><E><M><R><A><D><Y><N><R><H><H><F><V><R><D><D><S><F><K><G><T><W><D><L><L><D><A><Q><T><R><K><A><F><I><D><Y><L><E><R><S><C><V><S><E><F><S><G><F><L><L><F><K><E><L><S><R><K... | Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).<BOP> | Q8DI68 |
E7CLN1 | SCX4_RHOJU | Putative beta-neurotoxin RjAa4 | Rhopalurus | <K><E><G><Y><P><M><G><R><D><G><C><K><I><S><C><V><I><N><N><N><F><C><K><V><E><C><Q><A><K><W><R><Q><S><D><G><Y><C><Y><F><W><G><L><S><C><Y><C><T><N><L><P><D><D><A><Q><V><W><D><S><S><T><N><K><C><G><G> | Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.<BOP> | E7CLN1 |
Q6G3K0 | YIDD_BARHE | Putative membrane protein insertion efficiency factor | Bartonella | <M><F><N><P><Y><P><Q><K><K><K><R><Q><T><R><N><Y><T><G><P><W><R><K><T><P><G><R><L><L><G><L><L><L><I><R><F><Y><Q><I><T><L><S><G><F><I><G><N><Q><C><R><H><L><P><T><C><S><E><Y><T><Y><E><A><I><A><R><H><G><L><W><A><G><A><W><M><G><F><F><R><I><I><R><C><G><P><F><G><T><H><G><F><E><P><V><P><T><S><L><G><N><S><Y><C><F><Y><K><P><W><C... | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | Q6G3K0 |
Q6MS94 | ATPB_MYCMS | F-ATPase subunit beta | Mycoplasma | <M><V><S><K><N><T><T><D><K><K><K><N><Q><S><I><G><K><V><I><Q><V><L><G><S><V><V><D><V><K><F><S><E><N><S><I><P><K><I><Y><D><A><L><I><V><D><N><N><G><K><K><L><V><L><E><V><E><Q><N><I><G><D><E><I><V><R><T><I><A><M><G><P><T><E><G><L><K><R><G><L><D><V><I><N><T><N><S><P><I><T><A><P><T><G><M><E><V><L><G><R><M><F><N><V><L><G><D><P... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP> | Q6MS94 |
A5D178 | LSPA_PELTS | Signal peptidase II | Pelotomaculum | <M><F><L><F><I><I><I><A><V><V><L><L><V><D><Q><A><T><K><A><A><V><Q><M><L><M><C><Q><G><E><S><I><P><V><V><P><P><A><F><Y><L><T><Y><I><M><N><P><G><A><A><F><G><L><L><P><H><K><K><M><L><F><V><T><V><T><V><I><I><I><A><G><V><L><V><G><Y><F><K><I><R><P><R><K><P><V><L><D><Y><G><L><G><L><V><A><G><G><A><L><G><N><L><A><D><R><L><R><Y><G... | This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP> | A5D178 |
Q8K9C4 | DCDA_BUCAP | Diaminopimelate decarboxylase | Buchnera | <M><P><E><L><L><N><K><T><K><T><N><L><N><F><E><N><I><K><I><L><I><K><K><F><Q><S><P><F><W><V><Y><D><S><N><I><I><H><K><K><I><N><L><L><K><E><F><D><I><V><R><F><A><Q><K><A><C><S><N><I><H><I><L><R><L><M><K><Q><K><N><I><K><V><D><A><V><S><L><G><E><I><E><R><A><L><V><A><G><F><K><P><N><S><N><E><I><I><F><T><A><D><L><F><D><E><E><T><L... | Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.<BOP> | Q8K9C4 |
A6SM77 | EIF3E_BOTFB | Eukaryotic translation initiation factor 3 subunit E | Botrytis | <M><A><D><N><T><P><T><T><A><N><D><L><L><N><D><A><T><Q><A><A><A><K><S><P><E><E><I><A><K><E><N><D><L><L><P><K><L><I><T><H><L><D><R><H><L><I><F><P><L><L><Q><F><V><G><D><Q><D><D><E><P><S><P><E><I><T><K><A><K><F><E><L><L><K><K><T><N><M><T><D><Y><V><A><S><L><H><C><E><I><E><G><V><D><E><A><P><K><E><Y><A><N><K><R><Q><E><I><L><Q... | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t... | A6SM77 |
Q1H004 | NRDR_METFK | Transcriptional repressor NrdR | Methylobacillus | <M><K><C><P><F><C><G><A><D><D><T><Q><V><I><D><S><R><V><N><E><E><G><D><S><I><R><R><R><R><R><C><N><A><C><D><K><R><F><T><T><Y><E><T><A><E><L><H><L><P><Q><V><V><K><Q><N><G><K><R><E><E><F><N><R><D><K><L><R><L><S><F><T><R><P><L><H><K><R><P><V><P><T><E><Y><V><D><R><A><L><E><H><I><V><Q><K><I><L><A><K><G><E><R><E><I><M><A><R><D... | Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP> | Q1H004 |
P76393 | YEGI_ECOLI | Protein kinase YegI | Escherichia | <M><K><T><N><I><K><V><F><T><S><T><G><E><L><T><T><L><G><R><E><L><G><K><G><G><E><G><A><V><Y><D><I><E><E><F><V><D><S><V><A><K><I><Y><H><T><P><P><P><A><L><K><Q><D><K><L><A><F><M><A><A><T><A><D><A><Q><L><L><N><Y><V><A><W><P><Q><A><T><L><H><G><G><R><G><G><K><V><I><G><F><M><M><P><K><V><S><G><K><E><P><I><H><M><I><Y><S><P><A><H... | Probable serine/threonine kinase.<BOP> | P76393 |
P02257 | H1_ECHCR | Histone H1, gonadal | Echinolampas | <A><A><S><P><Q><K><R><A><A><S><P><R><K><S><P><K><K><S><P><R><K><S><P><K><K><K><S><P><R><K><R><K><A><R><S><A><A><H><P><P><V><I><D><M><I><T><A><A><I><A><A><Q><K><E><R><R><G><S><S><V><A><K><I><Q><S><Y><I><A><A><K><Y><R><C><D><I><N><A><L><N><P><H><I><R><R><A><L><K><N><Q><V><K><S><G><A><L><K><Q><V><S><G><V><G><A><T><G><R><F... | Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.<BOP> | P02257 |
P32014 | CTRB_NEIMB | Capsule polysaccharide export inner-membrane protein CtrB | Neisseria | <M><S><E><Q><L><P><V><A><V><A><T><E><T><K><A><E><R><K><K><P><K><K><K><S><W><I><K><K><L><S><P><L><F><W><V><T><V><I><I><P><T><V><I><S><L><V><Y><F><G><F><F><A><S><D><R><F><T><S><Q><S><S><F><V><V><R><S><P><K><S><Q><S><S><L><N><G><L><G><A><I><L><Q><G><T><G><F><A><R><A><Q><D><D><I><Y><T><V><G><E><Y><M><R><S><R><S><S><L><D><E... | May form an ATP-driven capsule polysaccharide export apparatus, in association with the CtrC and CtrD proteins.<BOP> | P32014 |
P69755 | O16C_CONMA | Delta-conotoxin-like MVIC | Pionoconus | <M><K><L><T><C><V><M><I><V><A><V><L><F><L><T><T><W><T><F><V><T><A><D><D><S><R><Y><G><L><K><N><L><F><P><K><A><R><H><E><M><K><N><P><E><A><S><K><L><N><K><R><D><E><C><Y><P><P><G><T><F><C><G><I><K><P><G><L><C><C><S><A><I><C><L><S><F><V><C><I><S><F><D><F> | Delta-conotoxins bind to site 6 of voltage-gated sodium channels (Nav) and inhibit the inactivation process.<BOP> | P69755 |
Q9YI19 | VM2MC_GLOBR | Disintegrin | Gloydius | <M><I><Q><V><L><L><V><I><I><C><L><A><D><F><P><Y><Q><G><T><S><I><I><L><E><S><G><N><V><N><D><Y><E><V><V><Y><P><R><K><V><T><A><L><P><K><G><A><V><Q><P><K><Y><E><D><A><M><Q><Y><E><F><K><V><N><G><E><P><V><V><L><H><L><E><K><N><K><G><L><F><S><K><G><Y><S><E><T><H><Y><S><P><D><G><R><K><I><T><T><N><P><P><V><E><D><H><C><Y><Y><H><G... | Inhibits ADP-induced platelet aggregation.<BOP> | Q9YI19 |
A7MIG6 | LPLA_CROS8 | Lipoate--protein ligase | Cronobacter | <M><S><S><L><R><L><L><I><S><D><S><Y><D><P><W><F><N><L><A><V><E><E><C><I><F><R><Q><M><P><A><T><Q><R><V><L><F><L><W><R><N><A><D><T><V><V><I><G><R><A><Q><N><P><W><K><E><C><N><T><R><R><M><E><E><D><N><V><R><L><A><R><R><S><S><G><G><G><A><V><F><H><D><L><G><N><T><C><F><T><F><M><A><G><K><P><E><Y><D><K><S><V><S><T><A><I><V><I><N... | Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.<BOP> | A7MIG6 |
Q21Y67 | CLPP_ALBFT | Endopeptidase Clp | Rhodoferax | <M><G><A><M><Q><T><Q><A><L><G><M><V><P><M><V><I><E><Q><S><G><R><G><E><R><S><Y><D><I><Y><S><R><L><L><K><E><R><V><I><F><L><V><G><P><V><N><D><Y><V><A><N><L><V><V><A><Q><L><L><F><L><E><S><D><N><P><D><K><D><I><S><F><Y><I><N><S><P><G><G><S><V><S><A><G><M><A><I><F><D><T><M><N><F><V><K><P><D><V><S><T><L><C><T><G><M><A><A><S><M... | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP> | Q21Y67 |
P44620 | LEP4_HAEIN | N-methyltransferase | Haemophilus | <M><I><Y><F><T><M><F><L><L><G><G><I><L><G><I><A><L><W><F><Y><L><S><G><F><I><T><R><L><Q><Q><N><I><Y><A><I><Y><V><E><L><F><P><Q><N><R><S><P><F><Q><P><H><F><A><S><I><Q><Q><K><K><C><G><H><I><L><R><Y><F><F><S><I><G><V><G><F><I><F><L><Q><I><A><F><K><D><S><I><F><T><V><W><I><G><L><T><L><I><I><L><W><T><I><S><Y><L><D><W><H><Y><Q... | Plays a role in type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. Substrates include proteins required for biogenesis of the type II general secretory apparatus.<BOP> | P44620 |
Q9HYL1 | NOSD_PSEAE | Probable ABC transporter binding protein NosD | Pseudomonas | <M><I><H><A><A><R><S><L><A><G><S><R><A><G><P><L><L><A><L><L><L><L><G><L><A><T><A><R><A><E><P><V><D><G><L><P><L><R><A><D><G><D><G><R><W><S><L><A><A><G><R><Y><A><G><N><F><V><I><D><R><P><L><H><L><R><C><E><A><G><A><E><L><D><G><G><G><H><G><S><L><L><T><L><T><S><P><G><I><T><V><E><G><C><R><L><R><N><W><G><R><N><L><T><E><L><D><A... | Required for the assembly of the copper chromophores of nitrous oxide reductase. Could be part of the ABC transporter complex NosDFY.<BOP> | Q9HYL1 |
A8FK14 | ARGC_CAMJ8 | N-acetyl-glutamate semialdehyde dehydrogenase | Campylobacter | <M><K><I><K><V><G><I><L><G><A><S><G><Y><A><G><N><E><L><V><R><I><L><L><N><H><P><K><V><E><I><S><Y><L><G><S><S><S><S><V><G><Q><N><Y><Q><D><L><Y><P><N><T><P><L><N><L><C><F><E><N><K><N><L><D><E><L><E><L><D><L><L><F><L><A><T><P><H><E><F><S><A><K><L><L><N><E><N><L><L><K><K><M><K><I><I><D><L><S><A><D><F><R><L><K><N><P><K><D><Y... | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP> | A8FK14 |
C0HLR8 | TX1_OCUSU | Kappa-lycotoxin-Os1a | Oculicosa | <R><L><A><L><P><P><G><A><V><C><N><G><H><K><S><D><C><Q><C><F><G><A><K><Y><K><C><S><C><P><F><F><W><R><F><R><K><S><A><E><C><H><C><K><K><G><W><A><W><T><A><I><K><K><R><S><C><H><N><R><Y><Q><W><S><D> | Insecticidal to house crickets . It induces an excitatory slow-onset impact that leads to irreversible spastic paralysis . It also modifies human voltage-gated potassium channel Kv1.5/KCNA5 . Most likely, it binds to the voltage-sensing domain of the channel, suggesting it does not block the pore but prevents its openi... | C0HLR8 |
Q53WI0 | HOA_THET8 | 4-hydroxy-2-oxopentanoate aldolase | Thermus | <M><S><W><D><L><S><T><A><K><P><P><V><V><V><D><T><T><L><R><D><G><S><H><A><H><R><H><Q><Y><T><V><E><E><A><R><A><I><A><Q><A><L><D><E><A><G><V><Y><A><I><E><V><S><H><G><D><G><L><G><G><S><S><L><Q><Y><G><F><S><R><T><D><E><M><E><L><I><R><A><V><R><E><T><V><R><R><A><K><V><A><A><L><L><L><P><G><I><G><T><R><K><E><L><K><E><A><V><E><A... | Catalyzes the retro-aldol cleavage of both 4-hydroxy-2-oxopentanoate (HOPA) and 4-hydroxy-2-oxohexanoate (HOHA) to pyruvate and acetaldehyde or propanaldehyde, respectively. The aldehydes produced by this reaction are directly channeled to the dehydrogenase TTHB247, ensuring that these toxic aldehydes are sequestered f... | Q53WI0 |
Q65RT1 | HSCB_MANSM | Co-chaperone protein HscB homolog | Basfia | <M><N><N><P><F><A><L><F><D><L><P><I><E><F><Q><L><D><Q><N><R><L><S><E><R><Y><L><A><L><Q><K><A><L><H><P><D><N><F><A><N><S><S><A><Q><E><Q><R><L><A><M><Q><K><S><A><E><V><N><D><A><L><Q><I><L><K><D><P><I><L><R><A><D><C><I><I><A><L><N><T><G><E><Q><Q><N><T><E><E><K><S><T><Q><D><M><A><F><L><M><Q><Q><M><Q><W><R><E><Q><L><E><E><I... | Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.<BOP> | Q65RT1 |
B6EJ04 | KTHY_ALISL | dTMP kinase | Aliivibrio | <M><S><K><F><I><V><I><E><G><L><E><G><A><G><K><S><T><A><I><K><N><V><L><A><T><L><A><K><H><G><I><T><A><P><V><T><T><R><E><P><G><G><T><P><L><A><E><K><M><R><E><L><V><K><Q><G><H><P><D><E><P><L><T><D><M><A><E><L><L><L><L><Y><A><A><R><A><Q><L><V><G><N><V><I><K><P><A><L><A><A><G><N><W><V><V><G><D><R><H><D><L><S><S><Q><A><Y><Q><G... | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP> | B6EJ04 |
O16259 | STIP1_CAEEL | Hsc70/Hsp90-organizing protein | Caenorhabditis | <M><T><D><A><A><I><A><E><K><D><L><G><N><A><A><Y><K><Q><K><D><F><E><K><A><H><V><H><Y><D><K><A><I><E><L><D><P><S><N><I><T><F><Y><N><N><K><A><A><V><Y><F><E><E><K><K><F><A><E><C><V><Q><F><C><E><K><A><V><E><V><G><R><E><T><R><A><D><Y><K><L><I><A><K><A><M><S><R><A><G><N><A><F><Q><K><Q><N><D><L><S><L><A><V><Q><W><F><H><R><S><L... | Plays a role in gonad development. Up-regulates longevity and thermotolerance. Binds daf-21/hsp90 and inhibits its ATPase activity.<BOP> | O16259 |
Q1CSC6 | FMT_HELPH | Methionyl-tRNA formyltransferase | Helicobacter | <M><R><I><V><F><M><G><T><P><G><F><A><E><V><I><L><R><A><L><V><E><N><K><N><N><H><I><E><V><V><G><L><F><T><Q><M><D><K><P><F><G><R><K><K><E><L><K><A><P><E><T><K><T><Y><I><L><E><N><H><L><N><I><P><I><F><Q><P><Q><S><L><K><E><P><E><V><Q><I><L><K><D><L><K><P><D><F><I><V><V><V><A><Y><G><K><I><L><P><K><E><V><L><T><I><A><P><C><I><N... | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP> | Q1CSC6 |
A9H3S4 | RL7_GLUDA | 50S ribosomal protein L7/L12 | Gluconacetobacter | <M><A><D><L><T><K><L><V><D><E><L><S><A><L><T><V><L><E><A><A><E><L><S><K><L><L><E><E><K><W><G><V><S><A><A><A><P><V><A><V><A><A><A><P><A><A><G><A><A><A><A><P><A><E><E><Q><T><E><F><T><V><V><L><A><K><A><G><D><K><K><I><N><V><I><K><E><I><R><G><I><T><G><L><G><L><K><E><A><K><D><L><V><E><G><A><P><K><T><V><K><E><G><V><N><K><D><E... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP> | A9H3S4 |
B5F6A8 | MUG_SALA4 | Mismatch-specific uracil DNA-glycosylase | Salmonella | <M><V><K><D><I><L><A><P><G><L><R><V><V><F><C><G><I><N><P><G><L><S><S><A><N><T><G><F><P><F><A><H><P><A><N><R><F><W><K><V><I><H><L><A><G><F><T><D><R><Q><L><K><P><E><E><A><E><K><L><L><D><F><R><C><G><V><T><K><L><V><D><R><P><T><V><Q><A><T><E><V><K><L><H><E><L><R><S><G><G><R><N><L><I><E><K><I><E><D><Y><Q><P><A><A><L><A><V><L... | Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanin... | B5F6A8 |
Q9TLY2 | CFXQ1_CYACA | Protein CfxQ homolog | Cyanidium | <M><G><I><T><P><T><A><L><E><K><T><D><K><H><T><L><V><N><L><Q><E><E><F><N><K><T><K><I><Q><E><V><L><D><D><L><N><Q><E><L><I><G><L><K><P><V><K><N><R><I><R><E><I><A><A><L><L><L><V><D><R><L><R><Q><K><V><G><L><S><S><S><N><P><G><L><H><M><S><F><T><G><P><P><G><T><G><K><T><T><V><A><T><K><M><A><D><I><L><Y><K><L><N><Y><I><K><K><G><H... | Necessary for the expression of RuBisCO.<BOP> | Q9TLY2 |
Q9M2R1 | GIG1_ARATH | Protein UV-B-INSENSITIVE 4-like | Arabidopsis | <M><P><E><A><R><D><R><T><E><R><P><V><D><Y><S><T><I><F><A><N><R><R><R><H><G><I><L><L><D><E><P><D><S><R><L><S><L><I><E><S><P><V><N><P><D><I><G><S><I><G><G><T><G><G><L><V><R><G><N><F><T><T><W><R><P><G><N><G><R><G><G><H><T><P><F><R><L><P><Q><G><R><E><N><M><P><I><V><T><A><R><R><G><R><G><G><G><L><L><P><S><W><Y><P><R><T><P><L... | Negative regulator of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase required for proper mitotic and meiotic progression and cell fate determination. Involved in entry into both meiosis I and meiosis II. Prevents endomitosis by preferentially inhibiting APC/C(CDC20). Required for megagametophyte and ... | Q9M2R1 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.