accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q22835
ZIP10_CAEEL
Transcription factor zip-10
Caenorhabditis
<M><T><T><M><T><N><S><L><I><S><N><S><V><S><S><V><P><E><S><L><F><S><S><A><S><I><H><R><P><V><A><I><N><P><A><M><L><A><Q><F><S><I><N><L><P><V><L><P><F><E><S><S><A><S><L><G><T><S><T><T><S><S><S><R><C><S><S><T><E><S><S><A><A><P><G><K><I><R><R><G><R><P><Q><Q><E><I><A><D><G><Q><D><A><H><S><Q><K><K><R><H><R><R><L><Y><A><R><Q><Y...
Transcription factor that regulates the expression of genes in response to changes in temperature. In particular, binds to the promoter region of genes such as asp-17 in response to severe cold to warm temperature transitions to promote gene expression. Promotes stress-induced death, particularly in older animals, foll...
Q22835
P83186
BRA_BASAL
Alpha-basrubrin
Basella
<G><A><D><F><Q><E><C><M><K><E><H><S><Q><K><Q><H><Q><H><Q><G>
Possesses antifungal activity against B.cinerea, M.arachidicola and F.oxysporum but not C.comatus and R.solani. Inhibits HIV-1 reverse transcriptase and cell-free translation.<BOP>
P83186
Q3YJT4
PT1K2_SOLTU
Patatin-1-Kuras 2
Solanum
<M><I><L><A><T><T><S><S><T><F><A><S><L><E><E><M><V><T><V><L><S><I><D><G><G><G><I><K><G><I><I><P><G><T><I><L><E><F><L><E><G><Q><L><Q><K><M><D><N><N><A><D><A><R><L><A><D><Y><F><D><V><I><G><G><T><S><T><G><G><L><L><T><A><M><I><T><T><P><N><E><N><N><R><P><F><A><A><A><N><E><I><V><P><F><Y><F><E><H><G><P><H><I><F><N><S><S><T><G...
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.<BOP>
Q3YJT4
A5VRI0
MRAY_BRUO2
UDP-MurNAc-pentapeptide phosphotransferase
Brucella
<M><L><M><F><L><T><H><F><A><E><H><V><T><P><F><N><V><F><R><Y><I><T><F><R><T><G><G><A><M><I><T><S><A><L><I><V><F><L><F><G><P><T><I><I><N><S><L><R><V><R><Q><G><K><G><Q><P><I><R><A><D><G><P><Q><T><H><F><K><K><A><G><T><P><T><M><G><G><L><M><I><M><T><G><I><L><A><S><C><L><L><W><A><N><L><A><S><V><Y><V><W><V><V><L><M><V><S><V><G...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
A5VRI0
A8WMY4
NRA1_CAEBR
Nicotinic receptor-associated protein 1
Caenorhabditis
<M><N><Q><P><I><A><A><I><G><I><S><D><S><T><R><P><K><T><N><V><R><L><T><I><S><A><E><H><L><M><D><T><D><V><F><S><K><S><D><P><I><C><L><V><Y><E><K><T><S><G><K><K><A><T><T><T><E><P><V><Q><V><P><T><W><Q><D><S><Q><W><T><E><R><G><R><T><E><V><V><M><N><N><L><N><P><Q><F><T><K><T><F><L><L><P><Y><F><F><E><E><T><Q><L><L><R><F><E><I><Y...
Exhibits calcium-dependent phospholipid binding properties. May function in membrane trafficking. Regulates synaptic levels of nicotinic acetylcholine receptor subunit lev-1 and unc-38 in the nerve cord. Involved in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine and levamisole. Affects direct...
A8WMY4
C3MZI0
PSB2_SULIA
Proteasome core protein PsmB 2
Sulfolobus
<M><E><E><L><P><A><T><A><I><G><L><K><V><N><D><G><I><V><L><A><S><E><R><R><L><S><Y><G><G><Y><V><L><S><K><Q><A><K><K><V><H><K><I><G><K><F><L><M><A><G><A><G><I><Y><G><D><L><Q><T><L><T><R><I><M><N><V><E><I><K><Y><Y><E><I><S><T><G><K><P><I><S><V><H><A><A><A><K><L><L><S><V><I><L><Y><Q><Y><K><V><M><P><F><I><S><E><I><L><F><G><G...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
C3MZI0
A5UDB0
RLMC_HAEIE
23S rRNA(m5U747)-methyltransferase
Haemophilus
<M><I><D><C><Q><Y><Y><Q><Q><N><E><C><R><S><C><Q><W><L><E><I><P><Y><D><Q><Q><I><A><E><K><Q><H><H><L><K><Q><Q><L><I><S><L><D><C><S><D><V><H><W><L><A><P><F><K><S><N><E><Q><G><F><R><N><K><A><K><M><L><V><S><G><S><V><E><R><P><I><L><G><I><L><K><N><P><N><D><P><Q><S><A><I><D><L><C><D><C><P><L><Y><P><A><H><F><S><I><I><F><S><I><L...
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.<BOP>
A5UDB0
A7ZCN3
RL11_CAMC1
50S ribosomal protein L11
Campylobacter
<M><A><K><K><V><I><G><E><I><K><L><Q><I><A><A><T><K><A><N><P><S><P><P><V><G><P><A><L><G><Q><K><G><V><N><I><M><E><F><C><K><A><F><N><E><K><T><K><D><M><V><G><F><N><I><P><V><V><I><T><V><Y><A><D><K><S><F><T><F><I><T><K><Q><P><P><A><T><D><L><I><K><K><A><A><G><I><T><K><G><T><D><N><P><L><K><N><K><V><G><K><L><T><K><A><Q><V><L><E...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
A7ZCN3
Q2JDQ7
CLPX_FRACC
ATP-dependent Clp protease ATP-binding subunit ClpX
Frankia
<M><A><R><I><G><D><G><G><D><L><L><K><C><S><F><C><G><K><S><Q><K><Q><V><K><K><L><I><A><G><P><G><V><Y><I><C><D><E><C><I><D><L><C><N><E><I><I><E><E><E><L><S><E><S><S><E><L><K><W><D><E><L><P><K><P><R><E><I><Y><E><F><L><D><S><Y><V><V><G><Q><E><T><A><K><K><T><L><S><V><A><V><Y><N><H><Y><K><R><V><Q><A><G><G><S><S><G><D><G><S><K...
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP>
Q2JDQ7
B5EBU6
TRPD_CITBB
Anthranilate phosphoribosyltransferase
Citrifermentans
<M><I><R><K><A><I><A><R><V><V><E><R><Q><D><L><S><E><A><E><M><I><E><V><M><D><Q><V><M><S><G><G><A><T><P><A><Q><I><A><S><F><I><T><A><L><R><M><K><G><E><T><V><D><E><I><T><G><A><A><R><V><M><R><D><R><A><L><P><I><R><V><G><K><S><V><L><G><I><D><R><D><D><I><N><L><D><R><E><T><I><L><D><T><C><G><T><G><G><S><G><T><N><S><F><N><I><S><T...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
B5EBU6
A0A1S4AX27
SCI1A_TOBAC
Style cell-cycle inhibitor 1-A
Nicotiana
<M><G><S><D><K><K><T><P><E><E><K><R><K><H><K><R><S><S><P><S><S><P><L><D><E><V><K><S><K><R><Q><N><I><K><G><D><E><E><R><R><K><E><K><K><D><K><S><K><K><E><K><H><K><S><H><S><S><E><E><K><K><S><G><E><K><H><K><T><K><S><H><K><H><K><D><K><S><K><N><K><F><E><E><L><S><K><D><D><Y><F><S><K><N><N><E><F><A><T><W><L><K><D><K><K><N><L><F...
Component of the auxin signaling transduction pathway that regulates cell proliferation and differentiation during flowers stigmas and styles development . Involved in the regulation of auxin-related genes .<BOP>
A0A1S4AX27
B1XAJ3
METE_ECODH
Methionine synthase, vitamin-B12 independent isozyme
Escherichia
<M><T><I><L><N><H><T><L><G><F><P><R><V><G><L><R><R><E><L><K><K><A><Q><E><S><Y><W><A><G><N><S><T><R><E><E><L><L><A><V><G><R><E><L><R><A><R><H><W><D><Q><Q><K><Q><A><G><I><D><L><L><P><V><G><D><F><A><W><Y><D><H><V><L><T><T><S><L><L><L><G><N><V><P><A><R><H><Q><N><K><D><G><S><V><D><I><D><T><L><F><R><I><G><R><G><R><A><P><T><G...
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.<BOP>
B1XAJ3
O08556
CCR5_RAT
MIP-1 alpha receptor
Rattus
<M><D><F><Q><G><S><I><P><T><Y><I><Y><D><I><D><Y><S><M><S><A><P><C><Q><K><V><N><V><K><Q><I><A><A><Q><L><L><P><P><L><Y><S><L><V><F><I><F><G><F><V><G><N><M><M><V><F><L><I><L><I><S><C><K><K><L><K><S><M><T><D><I><Y><L><F><N><L><A><I><S><D><L><L><F><L><L><T><L><P><F><W><A><H><Y><A><A><N><E><W><V><F><G><N><I><M><C><K><L><F><T...
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migrati...
O08556
B9DMC0
LUXS_STACT
Autoinducer-2 production protein LuxS
Staphylococcus
<M><P><K><M><N><V><E><S><F><N><L><D><H><T><K><V><V><A><P><F><V><R><L><A><G><T><V><E><G><A><N><G><D><V><I><K><K><Y><D><I><R><F><K><Q><P><N><K><E><H><M><K><M><P><G><L><H><S><L><E><H><L><M><A><E><N><I><R><N><H><T><D><K><V><V><D><L><S><P><M><G><C><Q><T><G><F><Y><V><S><L><I><N><H><D><D><Y><E><D><V><L><N><I><I><E><A><T><L><K...
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhom...
B9DMC0
C7MWV7
PSB_SACVD
Proteasome core protein PrcB
Saccharomonospora
<M><E><H><T><P><R><N><A><G><F><A><L><P><A><A><Y><M><S><T><M><T><S><S><F><I><D><F><L><K><A><E><A><P><D><L><L><P><R><A><R><V><E><N><M><P><A><V><P><G><G><G><S><A><F><E><P><P><H><G><T><T><I><V><A><S><T><F><N><G><G><V><L><I><A><G><D><R><R><A><T><T><G><N><T><I><A><S><R><D><L><E><K><V><Y><V><T><D><A><Y><S><A><V><G><I><A><G><T...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
C7MWV7
Q8K2B0
SC65_MOUSE
Synaptonemal complex protein SC65
Mus
<M><A><R><G><A><W><G><L><L><W><L><L><L><G><S><A><G><A><Q><Y><E><K><Y><S><F><R><G><F><P><P><E><D><L><M><P><L><A><T><A><Y><G><H><A><L><E><Q><Y><E><G><E><S><W><R><E><S><A><R><Y><L><E><A><A><L><R><L><H><R><L><L><R><D><S><E><A><F><C><H><A><N><C><S><G><P><A><T><S><Q><P><R><P><A><S><G><P><D><G><D><H><D><G><D><G><E><D><W><A><R...
Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linking of collagen fibrils . Required for normal bone density and normal skin stability via its role in hydroxylation of lysine residues in collagen ...
Q8K2B0
C4ZUV5
ALLA_ECOBW
Ureidoglycolatase
Escherichia
<M><K><L><Q><V><L><P><L><S><Q><E><A><F><S><A><Y><G><D><V><I><E><T><Q><Q><R><D><F><F><H><I><N><N><G><L><V><E><R><Y><H><D><L><A><L><V><E><I><L><E><Q><D><C><T><L><I><S><I><N><R><A><Q><P><A><N><L><P><L><T><I><H><E><L><E><R><H><P><L><G><T><Q><A><F><I><P><M><K><G><E><V><F><V><V><V><V><A><L><G><D><D><K><P><D><L><S><T><L><R><A...
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the anaerobic utilization of allantoin as sole nitrogen source. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.<BOP>
C4ZUV5
Q9U539
OCT1_CAEEL
CeOCT1
Caenorhabditis
<M><S><F><Q><A><M><E><T><F><A><E><I><S><Q><E><I><L><M><S><A><T><K><P><P><D><F><D><F><V><L><E><Q><V><G><N><Y><G><T><Y><Q><I><V><F><F><F><I><I><C><L><P><T><S><L><P><S><A><F><S><A><F><N><I><P><F><V><V><G><N><P><P><H><T><C><H><I><P><E><G><K><E><Y><L><R><P><L><T><N><D><T><Q><I><L><S><C><K><Q><Y><N><E><T><Q><I><N><V><F><R><A...
Transports organic cations such as tetraethylammonium (TEA). Displays a broad substrate specificity.<BOP>
Q9U539
O05337
PDRP_STAAU
Putative pyruvate, phosphate dikinase regulatory protein
Staphylococcus
<M><E><K><I><K><I><I><V><A><S><D><S><I><G><E><T><A><E><L><V><A><R><A><G><I><S><Q><F><N><P><K><Q><C><K><N><E><L><L><R><Y><P><Y><I><E><S><F><E><D><V><D><E><V><I><Q><V><A><K><D><T><N><A><I><I><V><Y><T><L><I><K><P><E><M><K><Q><Y><M><S><E><K><V><A><E><F><Q><L><K><S><V><D><I><M><G><P><L><M><D><L><L><S><A><S><V><E><E><K><P><Y...
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.<BOP>
O05337
P25966
ATPL_ALKAL
Lipid-binding protein
Alkalihalobacillus
<M><G><L><L><G><A><A><I><V><A><G><L><A><A><V><G><G><A><I><A><V><A><I><I><V><K><S><T><I><E><G><V><T><R><Q><P><E><L><K><G><T><L><Q><T><L><M><F><I><G><V><P><L><A><E><A><V><P><I><I><A><I><V><M><G><F><L><I><M><G><N><A>
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP>
P25966
Q89ZR7
PAND_BACTN
Aspartate 1-decarboxylase alpha chain
Bacteroides
<M><M><I><E><V><L><K><S><K><I><H><C><A><R><V><T><E><A><N><L><N><Y><M><G><S><I><T><I><D><E><D><L><L><D><A><A><N><M><I><P><G><E><K><V><Y><I><A><D><N><N><N><G><E><R><F><E><T><Y><I><I><K><G><E><R><G><S><G><K><I><C><L><N><G><A><A><A><R><K><V><Q><P><D><D><I><V><I><I><M><S><Y><A><L><M><D><F><E><E><A><K><S><F><K><P><T><V><I><F...
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.<BOP>
Q89ZR7
B3EWH2
AON_AZEFE
Azemiopsin
Azemiops
<D><N><W><W><P><K><P><P><H><Q><G><P><R><P><P><R><P><R><P><K><P>
In vitro, reversibly blocks human muscle-type nicotinic acetylcholine receptors (nAChR) alpha-1-beta-1-epsilon-delta/CHRNA1-CHRNB1-CHRNE-CHRND (EC(50)=0.44 uM) and alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND (EC(50)=1.56 uM). Binds to nAChR from T.californica (IC(50)=0.03-0.18 uM), human neuronal nAChR alpha-7...
B3EWH2
Q5LZD1
RNZ_STRT1
tRNase Z
Streptococcus
<M><E><L><Q><F><L><G><T><G><A><G><Q><P><S><K><A><R><N><V><S><S><L><V><L><K><L><L><D><E><I><N><E><V><W><M><F><D><C><G><E><G><T><Q><R><Q><I><L><E><T><T><I><K><P><R><K><V><K><K><I><F><I><T><H><M><H><G><D><H><I><F><G><L><P><G><F><L><A><S><R><S><F><Q><S><S><E><E><Q><T><D><L><E><V><Y><G><P><V><G><I><K><Q><Y><V><M><T><S><I><R...
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP>
Q5LZD1
B4SP14
OBG_STRM5
GTP-binding protein Obg
Stenotrophomonas maltophilia group
<M><K><L><V><D><E><A><E><I><E><V><F><A><G><N><G><G><N><G><C><I><G><F><R><R><E><K><F><I><P><L><G><G><P><D><G><G><D><G><G><A><G><G><S><V><Y><I><R><A><D><E><N><L><N><T><L><V><D><F><R><H><D><R><I><F><K><A><Q><R><G><E><N><G><M><G><R><Q><A><Y><G><K><G><G><E><D><L><T><I><T><V><P><V><G><T><V><I><I><N><V><A><T><D><E><I><I><G><D...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
B4SP14
A3DA26
ARGC_SHEB5
N-acetyl-glutamate semialdehyde dehydrogenase
Shewanella
<M><K><N><I><A><I><I><G><A><S><G><Y><T><G><A><Q><L><T><A><L><I><H><A><E><A><E><L><T><I><Q><G><L><Y><V><S><E><N><S><L><D><K><G><K><P><L><A><D><L><Y><P><S><Y><S><H><I><A><L><T><L><S><P><L><S><E><D><A><K><A><K><I><V><A><E><A><D><A><V><V><L><A><T><E><H><S><V><S><L><H><L><A><A><W><F><Y><S><Q><G><L><A><V><F><D><L><S><G><A><Y...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
A3DA26
A6WNN5
SERC_SHEB8
Phosphohydroxythreonine aminotransferase
Shewanella
<M><S><A><I><Y><N><F><C><A><G><P><A><M><L><P><A><A><V><M><K><K><A><Q><Q><E><L><L><D><W><N><G><Q><G><V><S><V><M><E><I><S><H><R><S><K><E><F><I><A><L><T><Q><Q><A><E><S><D><L><R><E><L><M><Q><I><P><T><N><Y><H><V><L><F><M><H><G><G><G><R><G><Q><F><S><A><V><V><N><N><F><L><G><N><H><G><R><A><L><Y><L><V><S><G><Q><W><S><S><A><A><L...
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.<BOP>
A6WNN5
A5FNY2
AROK_FLAJ1
Shikimate kinase
Flavobacterium
<M><E><K><I><V><L><L><G><Y><M><G><C><G><K><S><T><I><A><Q><N><L><S><K><I><T><Q><I><P><F><L><D><L><D><I><C><I><E><K><R><A><N><L><S><I><K><E><I><F><E><Q><H><G><E><I><Y><F><R><K><L><E><H><E><M><F><L><E><L><L><Q><S><S><E><N><A><I><I><G><L><G><G><G><T><P><C><Y><A><N><N><H><L><L><L><Q><R><D><D><I><V><S><V><Y><L><K><A><S><I><D...
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<BOP>
A5FNY2
Q5PN21
TUSC_SALPA
tRNA 2-thiouridine synthesizing protein C
Salmonella
<M><K><R><I><A><F><V><F><S><T><A><P><H><G><S><A><S><G><R><E><G><L><D><A><L><L><A><T><S><A><L><T><E><A><L><G><V><F><F><I><S><D><G><V><F><Q><L><L><P><G><Q><K><P><D><A><V><L><A><R><D><Y><I><A><T><F><K><L><F><D><L><Y><D><I><D><Q><C><W><I><C><A><A><S><L><R><E><R><G><L><E><N><V><N><F><V><V><N><A><T><P><L><E><P><V><A><L><R><R...
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.<BOP>
Q5PN21
A8GV48
RRF_RICB8
Ribosome-releasing factor
belli group
<M><D><K><V><T><L><K><K><N><L><Q><E><K><M><D><K><A><L><K><V><L><D><H><E><L><K><G><L><R><T><G><R><A><S><V><N><L><L><D><S><V><T><V><E><A><Y><G><D><R><M><P><L><S><Q><V><A><S><L><T><T><P><D><A><R><T><I><N><V><Q><V><W><D><K><S><M><V><S><S><V><E><K><A><I><T><V><A><N><L><G><L><T><P><S><S><D><G><Q><L><I><R><L><P><I><P><A><L><T...
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP>
A8GV48
O31854
CDAS_BACSU
Diadenylate cyclase
Bacillus
<M><K><A><M><R><Y><E><Q><I><S><E><N><A><F><K><G><K><I><Q><V><Y><L><E><Q><I><L><G><D><A><S><L><I><L><K><T><L><H><E><K><D><Q><C><L><L><C><E><L><D><D><L><G><H><V><F><Q><D><M><Q><G><I><A><S><S><F><Y><L><Q><S><Y><I><E><E><F><T><P><A><F><I><E><L><A><K><A><I><K><A><L><S><E><H><K><H><G><A><L><I><V><I><E><R><A><D><P><V><E><R><F...
One of 3 paralogous diadenylate cyclases (DAC) in this bacteria, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP) (Probable). Upon expression in E.coli leads to c-di-AMP synthesis . Overexpression of the hyperactive mutant (L44F) in the absence of c-di-AMP phosphodiesterase GdpP leads to gro...
O31854
P49518
RBCR_TRICV
Probable RuBisCO transcriptional regulator
Trieres
<M><T><L><P><F><T><L><Q><Q><L><R><I><L><K><A><I><A><T><E><K><S><F><T><R><A><A><E><V><L><F><V><S><Q><P><S><L><S><K><Q><I><K><T><L><E><S><R><L><N><I><S><L><L><N><R><E><N><N><I><V><S><L><T><Q><A><G><K><L><F><L><E><Y><S><E><R><I><L><A><L><C><E><E><S><C><R><V><L><N><D><L><K><T><G><D><R><G><N><L><I><V><G><A><S><Q><T><I><G><T...
Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression.<BOP>
P49518
Q9XI37
PV42A_ARATH
CBS domain-containing protein CBSCBS4
Arabidopsis
<M><Q><E><E><K><S><K><E><D><H><S><R><L><I><N><V><T><A><K><D><L><T><V><R><N><R><R><L><V><E><V><P><Y><T><A><T><L><S><H><A><M><N><T><L><V><A><N><S><I><S><A><L><P><V><A><A><P><P><G><H><W><I><G><A><G><G><S><M><I><M><E><S><D><K><Q><T><G><V><V><R><K><H><Y><I><G><I><L><T><M><L><D><I><L><A><H><I><A><G><E><D><S><N><L><S><D><L><D...
Plays redundant role with PV42b in regulating male gametogenesis and pollen tube guidance.<BOP>
Q9XI37
Q0ST16
HEM3_CLOPS
Pre-uroporphyrinogen synthase
Clostridium
<M><E><L><I><I><A><T><R><K><S><K><L><A><Q><V><Q><T><E><K><V><M><E><L><L><K><K><K><E><N><V><D><S><K><K><L><L><V><M><T><E><G><D><R><R><L><D><V><S><L><N><K><I><G><G><K><G><L><F><V><K><E><I><E><L><A><L><L><N><K><E><A><H><G><A><V><H><S><M><K><D><V><P><F><E><L><P><S><E><F><E><L><V><A><M><P><E><R><E><D><I><R><D><A><F><V><S><L...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
Q0ST16
A7HWJ3
SYT_PARL1
Threonyl-tRNA synthetase
Parvibaculum
<M><I><K><L><K><L><P><D><G><S><V><R><E><H><E><V><P><L><D><G><L><A><F><A><E><S><I><A><K><S><L><A><K><K><A><V><A><I><K><I><D><G><Q><M><K><D><L><S><T><V><I><D><R><D><A><E><V><E><I><V><T><R><E><T><P><D><G><V><D><L><L><R><H><D><A><S><H><V><M><A><E><A><V><Q><E><L><F><P><G><T><Q><V><T><I><G><P><V><I><E><N><G><F><Y><Y><D><F><A...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
A7HWJ3
O09160
FUT1_MOUSE
Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1
Mus
<M><W><T><P><S><R><R><Q><L><C><L><A><F><L><L><V><C><V><L><S><A><G><S><F><F><F><H><L><N><G><G><N><F><F><R><N><G><L><T><L><S><V><L><C><S><D><Y><H><L><L><K><S><P><V><A><M><V><C><L><P><H><P><L><Q><T><S><N><G><S><P><S><C><P><E><Q><S><S><S><L><S><G><T><W><T><I><T><P><G><G><R><F><G><N><Q><M><G><Q><Y><A><T><L><L><A><L><A><Q><L...
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens . H antigen is essential for maturation of the ...
O09160
P08281
GLNA2_PEA
Glutamate--ammonia ligase
Pisum
<M><A><Q><I><L><A><P><S><T><Q><W><Q><M><R><I><T><K><T><S><P><C><A><T><P><I><T><S><K><M><W><S><S><L><V><M><K><Q><T><K><K><V><A><H><S><A><K><F><R><V><M><A><V><N><S><E><N><G><T><I><N><R><V><E><D><L><L><N><L><D><I><T><P><F><T><D><S><I><I><A><E><Y><I><W><I><G><G><T><G><I><D><V><R><S><K><S><R><T><I><S><K><P><V><S><H><P><S><E...
The light-modulated chloroplast enzyme, encoded by a nuclear gene and expressed primarily in leaves, is responsible for the reassimilation of the ammonia generated by photorespiration.<BOP>
P08281
Q57DX4
FABH_BRUAB
3-oxoacyl-[acyl-carrier-protein] synthase III
Brucella
<M><I><R><S><V><V><R><G><I><G><S><A><L><P><K><R><V><M><K><N><T><D><F><E><G><I><V><E><T><S><D><E><W><I><V><Q><R><T><G><I><R><E><R><H><I><A><G><E><G><E><T><T><V><S><L><G><A><A><A><A><R><A><A><I><E><N><A><G><L><Q><P><S><D><I><D><L><V><L><L><A><T><S><T><P><N><N><T><F><P><A><S><A><V><A><I><Q><R><E><L><G><I><T><R><G><F><A><F...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
Q57DX4
A8YTF2
RL7_LACH4
50S ribosomal protein L7/L12
Lactobacillus
<M><A><L><D><T><D><K><I><I><E><E><L><K><G><A><S><I><L><E><L><N><D><L><V><K><A><I><E><D><E><F><D><V><T><A><A><A><P><V><A><A><A><G><A><A><D><A><G><A><A><K><S><E><F><D><V><E><L><T><E><A><G><Q><E><K><V><K><V><I><K><A><V><R><D><I><T><G><L><G><L><K><D><S><K><D><L><V><D><G><A><P><K><N><V><K><E><G><V><S><E><D><E><A><N><D><I><K...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP>
A8YTF2
Q822V6
GUAA_CHLCV
Glutamine amidotransferase
Chlamydia
<M><S><N><I><L><I><L><D><F><G><S><Q><Y><T><N><V><L><A><K><K><I><R><L><L><S><V><F><C><E><V><L><T><W><N><T><P><L><E><K><I><L><Q><I><S><P><S><G><L><I><F><S><G><G><P><H><S><V><Y><Q><E><N><S><P><K><V><D><K><E><I><Y><N><S><N><I><P><I><L><G><V><C><Y><G><M><Q><L><I><A><R><D><F><G><S><E><V><Q><G><G><K><S><E><F><G><Y><T><P><I><V...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q822V6
Q7MQZ8
RS6_WOLSU
30S ribosomal protein S6
Wolinella
<M><R><H><Y><E><T><M><F><I><V><K><P><T><L><T><P><E><E><I><V><E><K><I><N><F><Y><K><E><A><I><I><K><N><G><G><E><I><C><A><T><Q><D><M><G><M><R><N><L><A><Y><E><I><N><K><N><K><R><G><Y><Y><F><V><V><Y><F><K><S><A><P><S><L><V><I><E><L><E><R><L><Y><R><I><N><E><D><I><L><R><F><I><V><I><K><Y><E><S><K><K><E><Q><N><A><W><N><T><M><V><D...
Binds together with S18 to 16S ribosomal RNA.<BOP>
Q7MQZ8
A8MD44
METK_CALMQ
Methionine adenosyltransferase
Caldivirga
<M><A><R><N><I><V><V><S><G><I><R><R><P><P><T><E><D><L><P><V><E><L><V><E><R><K><G><L><G><H><P><D><Y><I><A><D><S><I><S><E><Y><V><S><R><E><L><S><K><Y><Y><M><E><N><F><G><T><I><L><H><H><N><V><D><K><V><L><V><I><G><G><N><A><Q><V><K><F><G><G><G><E><I><I><E><P><I><R><I><I><V><S><G><R><A><T><T><E><V><K><S><S><T><G><V><V><K><V><P...
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.<BOP>
A8MD44
Q732C1
CTAA_BACC1
Cytochrome aa3-controlling protein
Bacillus cereus group
<M><Q><R><F><I><K><W><L><A><V><I><T><S><L><D><L><L><I><V><L><L><G><G><A><L><V><T><K><T><G><S><G><Q><G><C><G><K><S><W><P><L><C><N><G><E><F><V><P><S><N><L><S><M><E><T><I><I><E><L><S><H><R><L><T><S><G><S><A><G><I><L><V><T><L><L><C><I><L><S><W><K><Y><Y><K><H><V><R><E><T><K><T><L><A><I><L><S><F><V><F><L><V><A><Q><A><L><M><G...
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.<BOP>
Q732C1
P59415
TRPD_BUCBP
Anthranilate phosphoribosyltransferase
Buchnera
<M><K><I><I><L><N><K><I><Y><Q><G><D><T><L><N><I><S><E><T><Y><T><L><F><K><S><I><M><L><K><K><I><N><N><I><E><L><S><A><I><L><I><A><L><K><I><R><G><E><S><Q><N><E><I><L><G><A><V><K><A><C><L><E><H><M><I><T><F><P><K><P><T><Y><M><F><S><D><I><V><G><T><G><G><D><N><S><N><S><I><N><I><S><T><T><S><A><L><V><G><S><A><C><G><F><K><I><A><K...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
P59415
A9M2I4
RSMH_NEIM0
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Neisseria
<M><S><G><A><E><S><Y><R><H><I><T><V><L><L><N><E><A><V><D><A><L><A><V><R><E><D><G><V><Y><V><D><G><T><F><G><R><G><G><H><S><R><L><I><L><S><R><L><G><D><A><G><R><L><I><V><F><D><K><D><P><Q><A><I><A><V><A><E><E><L><A><R><S><D><K><R><V><G><V><V><H><G><G><F><A><S><F><Q><T><A><L><D><G><L><G><I><G><K><V><D><G><A><L><F><D><L><G><I...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
A9M2I4
B1KF47
AROA_SHEWM
5-enolpyruvylshikimate-3-phosphate synthase
Shewanella
<M><K><Q><L><R><L><E><T><I><N><K><V><Q><G><T><V><N><I><P><G><S><K><S><I><S><N><R><A><L><L><L><A><T><L><A><K><G><T><T><T><L><T><N><L><L><D><S><D><D><I><R><Y><M><L><A><S><L><K><Q><L><G><V><N><Y><R><L><S><E><D><K><T><V><C><E><L><D><G><L><G><A><P><I><N><S><N><V><A><Q><T><L><F><L><G><N><A><G><T><A><M><R><P><L><C><A><A><L><T...
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP>
B1KF47
Q9JJN1
FGF21_MOUSE
Fibroblast growth factor 21
Mus
<M><E><W><M><R><S><R><V><G><T><L><G><L><W><V><R><L><L><L><A><V><F><L><L><G><V><Y><Q><A><Y><P><I><P><D><S><S><P><L><L><Q><F><G><G><Q><V><R><Q><R><Y><L><Y><T><D><D><D><Q><D><T><E><A><H><L><E><I><R><E><D><G><T><V><V><G><A><A><H><R><S><P><E><S><L><L><E><L><K><A><L><K><P><G><V><I><Q><I><L><G><V><K><A><S><R><F><L><C><Q><Q><P...
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity probably requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.<BOP>
Q9JJN1
Q1XDI6
RK5_NEOYE
50S ribosomal protein L5, chloroplastic
Neopyropia
<M><A><I><G><L><K><E><K><Y><K><T><T><V><T><Q><S><L><K><D><E><F><Q><Y><K><N><V><H><E><V><P><R><F><T><K><I><T><I><N><R><G><L><G><E><A><S><Q><N><A><K><A><L><E><S><S><I><Q><E><L><T><L><I><T><G><Q><K><P><I><V><T><K><A><K><K><S><I><A><G><F><K><I><R><E><E><V><P><I><G><I><V><V><H><L><R><K><D><K><M><Y><S><F><L><E><K><L><I><N><L...
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.<BOP>
Q1XDI6
Q8GT66
TIC40_PEA
Translocon at the inner envelope membrane of chloroplasts 40
Pisum
<M><E><N><L><N><L><A><L><V><S><S><P><K><P><L><L><L><G><H><S><S><S><K><N><V><F><S><G><R><K><S><F><T><F><G><T><F><R><V><S><A><N><S><S><S><S><H><V><T><R><A><A><S><K><S><H><Q><N><L><K><S><V><Q><G><K><V><N><A><H><D><F><A><S><I><S><S><S><N><G><Q><E><T><T><S><V><G><V><S><P><Q><L><S><P><P><P><P><S><T><V><G><S><P><L><F><W><I><G...
Involved in protein precursor import into chloroplasts. Part of the motor complex consisting of a co-chaperone (TIC40) and a chaperone (HSP93) associated with the import channel (TIC110). Causes the release of bound transit peptides from TIC110 and stimulates ATP hydrolysis by HSP93. Involved in reinsertion of proteins...
Q8GT66
O42493
NEUI_TAKRU
Neurophysin IT 1
Takifugu
<M><T><G><T><A><I><S><V><C><L><L><F><L><L><S><V><C><S><A><C><Y><I><S><N><C><P><I><G><G><K><R><S><I><M><D><A><P><Q><R><K><C><M><S><C><G><P><G><D><R><G><R><C><F><G><P><G><I><C><C><G><E><S><F><G><C><L><M><G><S><P><E><S><A><R><C><A><E><E><N><Y><L><L><T><P><C><Q><A><G><G><R><P><C><G><S><E><G><G><L><C><A><S><S><G><L><C><C><D...
Isotocin causes contraction of smooth muscles.<BOP>
O42493
Q3Z967
RS8_DEHM1
30S ribosomal protein S8
Dehalococcoides
<M><I><S><D><P><I><A><D><M><L><T><R><I><R><N><G><V><M><A><K><H><E><V><V><I><M><P><A><S><R><M><K><Q><Y><L><A><K><V><M><K><Q><E><G><F><I><A><G><Y><E><V><I><G><A><K><P><K><R><Q><L><K><I><V><L><R><Y><D><E><G><G><A><S><F><V><S><G><L><E><R><I><S><K><P><G><L><R><V><Y><V><Q><R><G><E><I><P><R><V><Y><G><G><L><G><I><A><I><V><S><T...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
Q3Z967
Q45410
EPSD_RALSL
NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase
Ralstonia
<M><D><R><A><I><E><I><D><F><R><T><I><S><V><V><G><L><G><Y><I><G><L><P><T><A><T><V><L><A><S><R><Q><R><E><L><I><G><V><D><I><N><Q><H><A><V><D><T><I><N><Q><A><R><I><H><I><V><E><P><D><L><D><M><L><V><R><A><A><V><S><Q><G><Y><L><R><A><T><T><E><P><E><P><A><D><A><F><L><I><A><V><P><T><P><F><L><E><D><K><Q><P><D><L><T><Y><I><E><A><A...
Probably involved in synthesis of sugar components of EPS I, by converting NDP-N-acetyl-D-galactosamine into NDP-N-acetyl-D-galactosaminuronic acid.<BOP>
Q45410
Q316L4
HIS6_OLEA2
ImGP synthase subunit HisF
Oleidesulfovibrio
<M><L><S><K><R><I><I><P><C><L><D><V><R><D><G><R><L><T><K><G><I><K><F><Q><G><N><V><D><I><G><D><P><V><E><S><A><R><R><Y><Y><E><Q><G><A><D><E><I><V><F><Y><D><I><T><A><S><H><E><G><R><G><I><F><L><D><I><V><E><K><V><A><S><S><I><F><I><P><F><S><V><G><G><G><I><N><T><V><D><D><M><R><D><A><L><N><A><G><A><E><K><V><S><V><N><S><G><A><V...
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP>
Q316L4
Q478V2
THIE_DECAR
Thiamine-phosphate pyrophosphorylase
Dechloromonas
<M><A><T><N><K><L><R><G><L><Y><A><I><T><P><D><R><A><D><G><A><R><L><L><A><D><V><E><A><A><L><A><G><G><C><R><V><V><Q><Y><R><D><K><L><S><T><M><P><E><Q><V><A><R><A><Q><A><L><R><E><L><T><R><R><F><A><A><T><L><L><I><N><D><D><L><A><L><A><A><L><V><Q><A><D><G><V><H><L><G><K><D><D><G><N><L><V><V><A><R><A><I><L><G><P><D><K><I><L><G...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
Q478V2
A4TEB1
XERC_MYCGI
Tyrosine recombinase XerC
Mycolicibacterium
<M><D><T><V><L><E><E><F><D><R><Y><L><E><L><E><R><G><R><S><E><H><T><R><R><A><Y><L><G><D><L><R><S><L><F><A><F><L><D><E><R><S><P><G><T><G><L><G><G><L><T><L><P><M><L><R><S><W><L><A><A><H><A><A><A><G><T><A><R><S><T><L><A><R><R><T><S><S><V><K><T><F><T><A><W><A><V><R><R><G><L><I><G><D><D><P><A><S><R><L><Q><V><P><K><A><R><R><T...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas...
A4TEB1
A3D186
APAH_SHEB5
Diadenosine tetraphosphatase
Shewanella
<M><A><H><Y><F><V><G><D><I><Q><G><C><F><A><E><L><Q><K><L><L><A><K><V><D><F><N><P><S><R><D><E><L><W><A><V><G><D><L><V><A><R><G><P><D><S><L><A><T><L><R><F><F><R><S><L><G><D><S><A><K><T><V><L><G><N><H><D><L><H><L><M><A><L><H><G><K><L><K><R><A><K><P><S><D><N><L><T><E><I><L><E><S><P><D><I><S><A><S><I><D><W><L><R><Q><Q><P><L...
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.<BOP>
A3D186
C5DGG6
ATP25_LACTC
ATPase synthesis protein 25, mitochondrial
Lachancea
<M><I><E><R><L><I><L><F><N><F><Q><S><D><K><N><T><K><H><T><R><V><R><N><M><L><L><R><R><A><A><A><A><L><P><A><R><K><T><P><L><H><C><Y><R><R><L><G><G><S><Y><R><A><L><S><G><S><L><L><L><R><D><E><E><K><R><L><P><H><R><V><Q><D><E><R><D><E><A><K><A><D><T><D><L><A><A><D><G><D><S><A><A><T><K><P><W><Y><L><N><I><V><E><R><P><A><Q><N><M...
Probable mitochondrial mRNA stabilization factor.<BOP>
C5DGG6
A0M3J8
GUAA_GRAFK
Glutamine amidotransferase
Gramella
<M><Q><N><N><V><L><I><L><D><F><G><S><Q><Y><T><Q><L><I><A><R><R><V><R><E><L><N><I><Y><C><E><I><Y><P><Y><H><K><I><P><E><D><L><S><G><F><K><A><V><I><L><S><G><S><P><F><S><V><R><A><E><D><A><P><H><P><D><L><S><Q><I><R><G><K><L><P><I><L><A><V><C><Y><G><A><Q><Y><F><A><H><F><H><G><G><K><V><E><P><S><D><T><R><E><Y><G><R><A><N><L><T...
Catalyzes the synthesis of GMP from XMP.<BOP>
A0M3J8
Q04G50
POTA_OENOB
Spermidine/putrescine import ATP-binding protein PotA
Oenococcus
<M><T><E><E><T><V><Q><P><L><I><E><F><K><N><V><S><L><D><Y><G><E><T><K><V><L><K><K><V><D><L><E><I><E><E><G><K><F><Y><T><L><L><G><P><S><G><S><G><K><S><T><I><L><S><L><I><S><G><R><L><Q><P><T><G><G><D><I><L><I><E><G><K><N><V><N><S><L><P><S><N><Q><R><K><V><N><T><V><F><Q><N><Y><A><L><F><P><N><M><N><V><Y><D><N><V><A><F><G><P><S...
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP>
Q04G50
Q9KAG5
RGMG_HALH5
Putative ribose/galactose/methyl galactoside import ATP-binding protein
Halalkalibacterium (ex Joshi et al. 2022)
<M><G><E><H><F><L><L><E><M><V><D><I><T><K><E><F><P><G><V><K><A><L><D><R><V><Q><L><K><V><R><K><G><S><V><H><A><L><M><G><E><N><G><A><G><K><S><T><L><M><K><I><L><I><G><M><Y><K><P><N><E><G><K><I><I><F><D><G><E><E><V><T><F><N><S><I><N><D><A><L><D><K><G><I><S><M><I><H><Q><E><L><S><P><I><P><E><M><T><V><A><E><N><I><F><L><G><R><E...
Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.<BOP>
Q9KAG5
C0QX60
GRPE_BRAHW
HSP-70 cofactor
Brachyspira
<M><E><E><E><I><K><E><T><S><E><D><K><E><E><E><N><T><E><A><E><A><V><E><N><N><E><K><S><E><E><N><A><G><N><V><E><E><D><E><I><T><A><L><K><K><R><I><E><E><L><E><N><E><S><A><D><M><K><N><K><Y><M><Y><A><M><A><E><A><E><N><I><R><K><R><T><A><K><E><K><A><D><S><I><K><R><A><N><K><G><L><L><L><S><L><L><T><F><M><D><N><F><E><R><A><L><K><A...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-b...
C0QX60
Q48ED3
CYSD_PSE14
Sulfate adenylate transferase
Pseudomonas
<M><V><D><K><L><T><H><L><K><Q><L><E><A><E><S><I><H><I><I><R><E><V><A><A><E><F><D><N><P><V><M><L><Y><S><I><G><K><D><S><A><V><M><L><H><L><A><R><K><A><F><F><P><G><K><L><P><F><P><V><M><H><V><D><T><R><W><K><F><Q><E><M><Y><R><F><R><D><K><M><V><E><E><M><G><L><D><L><I><T><H><I><N><P><D><G><V><A><Q><G><I><N><P><F><T><H><G><S><A...
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi...
Q48ED3
P42342
RR7_SPIMX
30S ribosomal protein S7, chloroplastic
Spirogyra
<M><S><R><R><S><N><T><V><S><R><P><T><K><P><D><P><I><Y><R><N><R><L><V><N><M><L><V><N><R><I><L><K><N><G><K><K><S><L><G><Y><R><I><L><Y><T><A><L><K><T><I><K><Q><K><T><K><K><N><P><L><S><V><L><R><Q><A><V><R><R><A><T><P><N><V><V><V><K><A><R><R><R><G><G><S><T><Y><Q><V><P><I><E><V><K><P><S><Q><G><R><A><L><A><I><R><W><L><L><S><A...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.<BOP>
P42342
A7ZSL0
RS10_ECO24
30S ribosomal protein S10
Escherichia
<M><Q><N><Q><R><I><R><I><R><L><K><A><F><D><H><R><L><I><D><Q><A><T><A><E><I><V><E><T><A><K><R><T><G><A><Q><V><R><G><P><I><P><L><P><T><R><K><E><R><F><T><V><L><I><S><P><H><V><N><K><D><A><R><D><Q><Y><E><I><R><T><H><L><R><L><V><D><I><V><E><P><T><E><K><T><V><D><A><L><M><R><L><D><L><A><A><G><V><D><V><Q><I><S><L><G>
Involved in the binding of tRNA to the ribosomes.<BOP>
A7ZSL0
B7V1F5
RBFA_PSEA8
Ribosome-binding factor A
Pseudomonas
<M><A><K><D><Y><S><R><T><Q><R><I><G><D><Q><M><Q><R><E><L><A><Q><L><I><Q><R><E><I><K><D><P><R><L><G><L><V><T><I><T><G><V><E><V><S><R><D><V><A><H><A><K><V><F><I><T><V><M><G><Q><D><D><A><G><K><I><A><L><N><M><E><I><L><N><D><A><A><G><Y><L><R><M><L><L><G><K><S><M><K><L><R><S><V><P><Q><L><H><F><H><Y><D><E><S><I><R><R><G><A><E...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
B7V1F5
B8E1E6
RS14Z_DICTD
30S ribosomal protein S14 type Z
Dictyoglomus
<M><A><K><K><S><Q><I><V><K><W><L><K><P><K><K><Y><K><V><R><E><Y><N><R><C><R><I><C><G><R><P><R><G><Y><I><R><K><F><G><L><C><R><L><C><F><R><E><L><A><L><K><G><E><I><P><G><V><R><K><A><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
B8E1E6
Q4URH2
MDH_XANC8
Malate dehydrogenase
Xanthomonas
<M><K><A><P><V><R><V><A><V><T><G><A><A><G><Q><I><G><Y><A><L><L><F><R><I><A><S><G><E><M><L><G><K><D><Q><P><V><I><L><Q><L><L><E><L><S><N><E><K><A><Q><A><A><L><K><G><V><M><M><E><L><E><D><C><A><F><P><L><L><A><G><M><V><G><T><D><D><A><E><V><A><F><K><D><I><D><V><A><L><L><V><G><A><R><P><R><G><P><G><M><E><R><K><D><L><L><L><E><N...
Catalyzes the reversible oxidation of malate to oxaloacetate.<BOP>
Q4URH2
Q0CPB0
KYNU1_ASPTN
L-kynurenine hydrolase 1
Aspergillus subgen. Circumdati
<M><G><S><R><L><H><L><R><D><I><K><H><G><P><P><L><P><Y><H><D><D><I><R><A><F><T><K><E><Y><A><E><S><L><D><A><Q><D><P><L><R><K><F><R><D><E><F><I><I><P><S><K><K><D><L><K><R><T><V><L><A><A><D><E><N><T><D><D><S><T><D><P><R><C><I><Y><L><C><G><N><S><L><G><L><Q><P><R><S><T><R><K><Y><I><D><R><Y><L><R><T><W><A><I><K><G><V><T><G><H...
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.<BOP>
Q0CPB0
Q96H86
ZN764_HUMAN
Zinc finger protein 764
Homo
<M><A><P><P><L><A><P><L><P><P><R><D><P><N><G><A><G><P><E><W><R><E><P><G><A><V><S><F><A><D><V><A><V><Y><F><C><R><E><E><W><G><C><L><R><P><A><Q><R><A><L><Y><R><D><V><M><R><E><T><Y><G><H><L><S><A><L><G><I><G><G><N><K><P><A><L><I><S><W><V><E><E><E><A><E><L><W><G><P><A><A><Q><D><P><E><V><A><K><C><Q><T><Q><T><D><P><A><D><S><R...
May be involved in transcriptional regulation.<BOP>
Q96H86
Q57HA8
KATG_SALCH
Peroxidase/catalase
Salmonella
<M><S><T><T><D><D><T><H><N><T><L><S><T><G><K><C><P><F><H><Q><G><G><H><D><R><S><A><G><A><G><T><A><S><R><D><W><W><P><N><Q><L><R><V><D><L><L><N><Q><H><S><N><R><S><N><P><L><G><E><D><F><D><Y><R><K><E><F><S><K><L><D><Y><S><A><L><K><G><D><L><K><A><L><L><T><D><S><Q><P><W><W><P><A><D><W><G><S><Y><V><G><L><F><I><R><M><A><W><H><G...
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP>
Q57HA8
A1JNR2
THII_YERE8
tRNA 4-thiouridine synthase
Yersinia
<M><K><F><I><I><K><L><F><P><E><I><T><I><K><S><Q><S><V><R><L><R><F><I><K><I><L><T><T><N><I><R><N><V><L><K><N><L><E><D><D><T><L><A><V><V><R><H><W><D><H><I><E><I><R><T><K><D><D><N><L><G><P><Q><I><C><D><A><L><T><R><V><P><G><I><H><H><I><L><E><V><E><D><R><S><Y><T><D><M><H><N><I><F><E><Q><T><L><E><A><Y><R><E><T><L><I><G><K><T...
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt...
A1JNR2
P31656
CADH_MEDSA
Probable cinnamyl alcohol dehydrogenase
Medicago
<M><G><S><I><E><A><A><E><R><T><T><V><G><L><A><A><K><D><P><S><G><I><L><T><P><Y><T><Y><T><L><R><N><T><G><P><D><D><V><Y><I><K><I><H><Y><C><G><V><C><H><S><D><L><H><Q><I><K><N><D><L><G><M><S><N><Y><P><M><V><P><G><H><E><V><V><G><E><V><L><E><V><G><S><N><V><T><R><F><K><V><G><E><I><V><G><V><G><L><L><V><G><C><C><K><S><C><R><A><C...
This protein catalyzes the final step in a branch of phenylpropanoid synthesis specific for production of lignin monomers. It acts on coniferyl-, sinapyl-, 4-coumaryl- and cinnamyl-alcohol.<BOP>
P31656
A2CC34
RL16_PROM3
50S ribosomal protein L16
Prochlorococcus
<M><L><S><P><K><R><V><K><F><R><K><Q><Q><R><G><R><M><R><G><V><A><T><R><G><N><T><I><A><F><G><E><F><A><L><Q><A><Q><E><C><G><W><I><T><S><R><Q><I><E><A><S><R><R><A><M><T><R><Y><V><K><R><G><G><K><I><W><I><R><I><F><P><D><K><P><V><T><M><R><P><A><E><T><R><M><G><S><G><K><G><N><P><E><F><W><V><A><V><I><K><P><G><R><I><L><F><E><M><G...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
A2CC34
P12112
ATPA_WHEAT
F-ATPase subunit alpha
Triticum
<M><A><T><L><R><V><D><E><I><H><K><I><L><R><E><R><I><E><Q><Y><N><R><K><V><G><I><E><N><I><G><R><V><V><Q><V><G><D><G><I><A><R><I><I><G><L><G><E><I><M><S><G><E><L><V><E><F><A><E><G><T><R><G><I><A><L><N><L><E><S><K><N><V><G><I><V><L><M><G><D><G><L><M><I><Q><E><G><S><F><V><K><A><T><G><R><I><A><Q><I><P><V><S><E><A><Y><L><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
P12112
Q8NH74
O10A6_HUMAN
Olfactory receptor OR11-96
Homo
<M><E><R><Q><N><Q><S><C><V><V><E><F><I><L><L><G><F><S><N><Y><P><E><L><Q><G><Q><L><F><V><A><F><L><V><I><Y><L><V><T><L><I><G><N><A><I><I><I><V><I><V><S><L><D><Q><S><L><H><V><P><M><Y><L><F><L><L><N><L><S><V><V><D><L><S><F><S><A><V><I><M><P><E><M><L><V><V><L><S><T><E><K><T><T><I><S><F><G><G><C><F><A><Q><M><Y><F><I><L><L><F...
Odorant receptor.<BOP>
Q8NH74
A3NQX6
LIPA_BURP0
Sulfur insertion protein LipA
pseudomallei group
<M><T><D><L><T><A><T><P><A><P><A><E><P><A><A><S><A><Y><D><P><T><A><K><Q><K><A><Q><A><K><T><A><R><I><P><I><K><I><V><P><I><E><K><L><K><K><P><E><W><I><R><V><K><A><A><T><G><S><S><R><F><N><E><I><K><T><I><L><R><E><H><N><L><H><T><V><C><E><E><A><S><C><P><N><I><G><E><C><F><G><K><G><T><A><T><F><M><I><M><G><D><K><C><T><R><R><C><P...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
A3NQX6
B8JEH9
TTCA_ANAD2
tRNA 2-thiocytidine biosynthesis protein TtcA
Anaeromyxobacter
<M><Q><Q><I><H><R><L><E><R><K><L><L><R><A><T><A><E><A><I><R><D><F><D><L><V><S><Q><G><D><R><I><M><V><A><V><S><G><G><K><D><S><Y><T><L><L><H><L><L><M><R><L><R><E><R><A><P><I><D><F><D><L><V><A><V><N><L><D><Q><G><Q><P><G><F><P><A><Q><V><V><E><D><H><L><R><S><V><G><V><P><Y><R><M><L><Q><R><D><T><Y><S><V><V><R><R><L><V><P><E><G...
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP>
B8JEH9
B5RL25
DDL_BORDL
D-alanylalanine synthetase
Borrelia
<M><K><K><N><L><M><L><I><F><G><G><V><S><F><E><H><E><I><S><L><R><S><A><Y><G><I><Y><S><S><L><L><K><L><D><K><Y><N><V><F><S><V><F><V><D><K><V><T><G><I><W><Y><L><L><D><S><V><P><S><S><A><E><L><I><K><R><H><T><T><S><I><V><N><F><I><P><G><C><G><I><F><V><N><N><K><S><L><E><I><D><V><I><F><P><I><I><H><G><R><T><G><E><D><G><A><I><Q><G...
Cell wall formation.<BOP>
B5RL25
Q5QWR3
KAD_IDILO
Adenylate monophosphate kinase
Idiomarina
<M><R><I><I><L><L><G><A><P><G><A><G><K><G><T><Q><A><Q><F><L><M><N><T><F><G><I><P><Q><I><S><T><G><D><M><L><R><S><A><I><K><S><G><S><E><L><G><K><K><A><K><Q><V><M><D><A><G><Q><L><V><S><D><D><I><I><I><E><L><V><K><E><R><I><A><E><P><D><C><Q><N><G><F><L><L><D><G><F><P><R><T><I><P><Q><A><D><A><M><R><D><N><G><I><E><I><D><Y><V><L...
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP>
Q5QWR3
Q32PD0
FCF1_BOVIN
rRNA-processing protein FCF1 homolog
Bos
<M><G><K><Q><K><K><T><R><K><Y><A><T><M><K><R><M><L><S><L><R><D><Q><R><L><K><E><K><D><R><L><K><P><K><K><K><E><K><K><D><P><S><A><L><K><E><R><E><V><P><Q><H><P><S><C><L><F><F><Q><Y><N><T><Q><L><G><P><P><Y><H><I><L><V><D><T><N><F><I><N><F><S><I><K><A><K><L><D><L><V><Q><S><M><M><D><C><L><Y><A><K><C><I><P><C><I><T><D><C><V><M...
Essential protein involved in pre-rRNA processing and 40S ribosomal subunit assembly.<BOP>
Q32PD0
Q886Q4
DAPE_PSESM
N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Pseudomonas
<M><T><A><P><A><D><L><S><P><T><L><Q><L><A><C><D><L><I><R><R><P><S><V><T><P><V><D><A><D><C><Q><T><V><M><M><Q><R><L><G><D><A><G><F><K><L><E><P><M><R><I><E><D><V><D><N><F><W><A><T><H><G><T><R><E><G><P><V><L><C><F><A><G><H><T><D><V><V><P><T><G><P><V><Q><D><W><Q><N><D><P><F><D><A><L><I><D><E><H><G><M><L><C><G><R><G><A><A><D...
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP>
Q886Q4
A4WLW1
G1PDH_PYRAR
sn-glycerol-1-phosphate dehydrogenase
Pyrobaculum
<M><K><Q><L><E><S><F><E><I><P><R><T><V><I><F><G><P><G><A><I><S><K><T><P><Q><V><V><A><K><H><K><A><E><R><I><L><I><I><S><G><K><S><V><T><A><N><Y><A><N><E><V><A><H><L><L><S><G><Y><S><V><D><V><V><R><Y><D><E><V><D><T><S><Y><S><K><Y><D><L><V><L><G><V><G><G><G><R><P><I><D><V><A><K><V><Y><S><Y><L><H><R><A><P><L><I><V><I><P><T><S...
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.<BOP>
A4WLW1
Q6D3J9
RL25_PECAS
50S ribosomal protein L25
Pectobacterium
<M><I><T><I><K><A><E><A><R><Q><G><Q><G><K><G><A><S><R><R><L><R><S><A><G><K><F><P><A><I><V><Y><G><G><S><E><A><P><V><S><I><E><L><D><H><D><S><V><K><N><Q><E><V><K><E><G><F><Y><G><E><T><L><I><L><S><I><D><G><K><E><V><Q><V><K><V><Q><A><V><Q><R><H><V><Y><K><P><K><L><T><H><I><D><F><V><R><V>
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
Q6D3J9
B4EY51
NCPP_PROMH
Nucleoside-triphosphate phosphatase
Proteus
<M><Y><H><V><I><A><A><T><T><N><P><A><K><I><N><A><I><K><L><A><F><E><Q><V><F><G><K><D><T><F><D><I><E><D><I><N><V><D><S><R><V><P><Q><Q><P><I><G><N><T><E><T><R><T><G><A><R><Q><R><V><M><A><A><R><Q><V><R><P><E><A><D><F><W><V><G><V><E><A><G><I><E><D><D><M><T><F><A><W><I><V><I><E><H><E><Q><I><R><G><E><S><R><S><A><S><L><M><L><P...
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.<BOP>
B4EY51
Q6DAV4
FPG_PECAS
DNA-(apurinic or apyrimidinic site) lyase MutM
Pectobacterium
<M><P><E><L><P><E><V><E><T><S><R><R><G><I><S><P><Y><L><V><G><H><T><I><L><Y><A><E><V><R><N><A><R><L><R><W><P><V><S><A><E><I><L><S><L><S><D><E><P><V><L><S><V><R><R><R><A><K><Y><L><L><I><E><L><T><H><G><W><I><I><V><H><L><G><M><S><G><S><L><R><I><L><P><E><Y><S><E><P><E><K><H><D><H><V><D><L><V><M><D><S><G><K><V><L><R><Y><T><D...
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ...
Q6DAV4
Q98F84
TOLB_RHILO
Tol-Pal system protein TolB
Mesorhizobium
<M><R><S><F><L><K><P><L><L><T><I><A><A><M><A><L><G><M><T><A><V><I><P><M><P><A><W><A><L><V><E><L><N><V><N><K><G><N><V><E><P><L><P><I><A><I><T><D><F><Q><G><G><D><A><L><G><A><Q><I><S><Q><I><V><T><A><D><L><K><R><S><G><L><F><A><P><I><D><K><S><A><F><I><E><K><I><S><N><P><D><A><A><P><R><F><D><D><W><K><V><I><N><A><Q><A><L><V><T...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
Q98F84
B8G1Y1
RL6_DESHD
50S ribosomal protein L6
Desulfitobacterium
<M><S><R><I><G><K><R><P><I><S><I><P><G><G><V><D><V><N><I><E><G><N><V><V><T><V><K><G><P><K><G><T><L><T><K><E><M><H><S><L><I><N><I><A><V><E><E><Q><Q><I><V><V><T><R><P><D><D><Q><P><L><S><R><S><L><H><G><L><T><R><T><L><V><A><N><M><V><E><G><V><T><K><G><F><S><K><S><L><D><M><V><G><V><G><Y><R><A><A><K><Q><G><N><K><L><V><L><S><V...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
B8G1Y1
Q5F4Z1
ATPG_NEIG1
F-ATPase gamma subunit
Neisseria
<M><A><V><G><K><E><I><L><T><K><I><R><S><V><Q><N><T><Q><K><I><T><K><A><M><Q><M><V><S><T><S><K><M><R><K><T><Q><E><R><M><S><L><A><R><P><Y><A><E><K><V><R><M><V><M><S><H><L><A><Q><T><N><T><D><H><G><I><P><L><L><E><S><H><R><E><I><R><R><V><G><F><I><L><I><T><S><D><K><G><L><C><G><G><L><N><A><N><V><L><K><K><F><L><A><Q><V><Q><E><Y...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
Q5F4Z1
Q3J7B4
RL13_NITOC
50S ribosomal protein L13
Nitrosococcus
<M><K><T><F><S><A><K><P><K><E><V><R><R><D><W><Y><L><V><D><A><N><G><V><T><L><G><R><L><A><S><E><I><A><R><R><L><R><G><K><H><K><A><I><Y><T><P><H><I><D><T><G><D><Y><I><V><V><V><N><A><E><K><I><R><A><T><G><K><K><M><A><Q><K><H><Y><Y><R><H><S><G><Y><P><G><G><I><K><S><L><T><L><E><K><L><L><E><R><A><P><E><R><A><I><E><L><A><V><K><G...
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.<BOP>
Q3J7B4
Q31L16
RS17_SYNE7
30S ribosomal protein S17
Synechococcus
<M><A><V><K><E><R><V><G><V><V><V><S><D><K><M><D><K><T><V><V><V><A><I><E><D><R><T><A><H><P><K><Y><G><K><I><V><V><R><T><K><R><Y><K><A><H><D><E><D><N><R><A><K><T><G><D><R><V><R><I><Q><E><T><R><P><L><S><R><T><K><R><W><T><V><A><E><I><L><E><S><V><G><A>
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP>
Q31L16
A5FUK7
MRAY_ACICJ
UDP-MurNAc-pentapeptide phosphotransferase
Acidiphilium
<M><L><Y><A><L><L><L><P><H><V><A><A><F><H><A><F><N><L><I><R><Y><I><T><F><R><A><G><G><A><C><L><T><A><L><V><V><S><F><L><L><G><P><R><L><I><R><W><L><K><S><L><Q><K><Q><G><Q><P><I><R><A><D><G><P><E><R><H><L><I><E><K><K><G><T><P><T><M><G><G><F><L><I><L><I><A><L><T><V><S><T><L><L><W><A><D><L><R><N><G><Y><V><W><A><V><L><M><I><T...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
A5FUK7
A1TC25
NDK_MYCVP
Nucleoside-2-P kinase
Mycolicibacterium
<M><T><E><R><T><L><V><L><I><K><P><D><G><V><Q><R><R><L><I><G><E><I><I><S><R><I><E><A><K><G><L><T><V><A><A><L><E><L><K><N><V><D><D><A><L><A><R><A><H><Y><A><E><H><E><G><K><P><F><F><A><S><L><L><E><F><I><T><S><G><P><V><V><A><A><I><L><E><G><P><R><A><I><A><A><F><R><Q><L><A><G><G><T><D><P><V><E><K><A><T><P><G><T><I><R><G><D><L...
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP>
A1TC25
A4WGA0
RHAM_ENT38
Type-3 mutarotase
Enterobacter
<M><I><R><K><A><F><V><M><Q><V><N><P><D><S><H><D><E><Y><E><R><R><H><T><P><I><W><P><E><L><E><S><V><L><K><D><H><G><A><H><H><Y><A><I><Y><L><D><K><A><R><N><L><L><F><A><T><V><E><I><E><S><E><E><R><W><N><A><V><A><H><T><D><V><C><Q><R><W><W><K><H><M><R><D><V><M><P><S><N><P><D><N><S><P><V><S><A><E><L><K><E><V><F><Y><L><D>
Involved in the anomeric conversion of L-rhamnose.<BOP>
A4WGA0
P0AAH9
SAPF_ECOL6
Peptide transport system ATP-binding protein SapF
Escherichia
<M><I><E><T><L><L><E><V><R><N><L><S><K><T><F><R><Y><R><T><G><W><F><R><R><Q><T><V><E><A><V><K><P><L><S><F><T><L><R><E><G><Q><T><L><A><I><I><G><E><N><G><S><G><K><S><T><L><A><K><M><L><A><G><M><I><E><P><T><S><G><E><L><L><I><D><D><H><P><L><H><F><G><D><Y><S><F><R><S><Q><R><I><R><M><I><F><Q><D><P><S><T><S><L><N><P><R><Q><R><I...
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.<BOP>
P0AAH9
Q94F30
ESD4_ARATH
Protein EARLY IN SHORT DAYS 4
Arabidopsis
<M><G><A><V><A><I><N><R><K><R><S><D><E><S><F><N><F><I><N><Q><Q><S><T><N><P><L><R><N><S><P><Y><F><Q><A><S><K><K><R><R><F><S><F><A><M><S><E><D><S><G><K><P><A><S><S><N><P><T><I><S><R><I><S><R><Y><P><D><A><K><A><P><L><R><R><E><I><H><A><P><S><R><G><I><L><R><Y><G><K><A><K><S><N><D><Y><C><E><K><D><A><N><F><F><V><R><K><Y><D><D...
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins. Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5. Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3. Acts predom...
Q94F30
O26542
UVRB_METTH
Excinuclease ABC subunit B
Methanothermobacter
<M><M><K><F><K><L><V><S><D><Y><R><P><L><G><D><Q><P><K><A><I><R><S><L><V><N><G><I><K><A><G><M><R><E><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><V><A><N><V><I><A><E><V><Q><K><P><T><L><V><I><S><H><N><K><T><L><A><A><Q><L><Y><E><E><F><R><E><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><F><Y><Q><P><E><A><Y><I><P><Q><T><D><T><Y...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
O26542
A8H5M1
MNMA_SHEPA
tRNA-specific 2-thiouridylase MnmA
Shewanella
<M><T><S><I><E><P><T><H><L><G><K><K><V><I><V><G><M><S><G><G><V><D><S><S><V><S><A><Y><L><L><M><K><Q><G><Y><Q><V><E><G><L><F><M><K><N><W><E><E><D><D><T><D><E><Y><C><A><A><A><D><D><L><K><D><A><Q><A><V><C><D><K><L><G><I><K><L><H><T><V><N><F><A><S><E><Y><W><D><N><V><F><E><Y><F><L><A><E><Y><K><A><G><R><T><P><N><P><D><I><M><C...
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP>
A8H5M1
Q19V65
ATPB_CHLAT
F-ATPase subunit beta
Chlorokybus
<M><T><T><T><N><A><V><K><T><K><N><I><G><Y><I><T><Q><I><I><G><P><V><M><D><V><K><F><S><P><G><K><M><P><N><I><Y><N><A><L><I><V><N><G><K><N><E><A><G><D><E><I><S><V><T><C><E><V><Q><Q><L><L><G><D><N><K><V><R><A><I><S><M><S><G><T><D><G><L><M><R><G><M><E><V><L><D><T><G><A><P><L><S><V><P><V><G><E><A><T><L><G><R><I><F><N><V><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q19V65
Q52953
MURD_RHIME
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Sinorhizobium
<M><I><P><V><T><S><F><K><G><R><K><V><A><L><F><G><L><G><G><S><G><L><A><T><A><Q><A><L><V><S><G><G><A><D><V><V><A><W><D><D><N><P><D><S><V><A><K><A><A><A><A><G><I><A><T><A><D><L><R><G><A><D><W><H><A><F><A><A><F><V><L><S><P><G><V><P><L><T><H><P><K><P><H><W><S><V><D><L><A><H><Q><A><G><V><E><I><I><G><D><V><E><L><F><V><R><E><R...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q52953
Q02U08
YQGF_PSEAB
Putative pre-16S rRNA nuclease
Pseudomonas
<M><A><S><D><K><P><L><R><L><L><L><G><F><D><Y><G><T><R><Q><I><G><V><A><V><G><Q><A><V><T><G><Q><A><R><E><L><C><V><L><K><A><Q><N><G><V><P><D><W><N><R><V><E><A><L><I><K><E><W><Q><P><D><A><I><V><V><G><L><P><L><N><M><D><G><S><P><S><E><M><S><E><R><A><E><K><F><G><R><R><L><N><G><R><F><N><L><P><V><F><T><H><D><E><R><L><T><T><Y><A...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
Q02U08
P39962
KC13_YEAST
Casein kinase I homolog 3
Saccharomyces
<M><S><Q><R><S><S><Q><H><I><V><G><I><H><Y><A><V><G><P><K><I><G><E><G><S><F><G><V><I><F><E><G><E><N><I><L><H><S><C><Q><A><Q><T><G><S><K><R><D><S><S><I><I><M><A><N><E><P><V><A><I><K><F><E><P><R><H><S><D><A><P><Q><L><R><D><E><F><R><A><Y><R><I><L><N><G><C><V><G><I><P><H><A><Y><Y><F><G><Q><E><G><M><H><N><I><L><I><I><D><L><L...
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.<BOP>
P39962