accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q4UKQ3 | RLUC_RICFE | rRNA-uridine isomerase C | spotted fever group | <M><I><I><D><V><N><T><P><I><S><S><R><L><D><K><Y><L><K><R><L><Y><P><L><L><T><Q><G><V><I><E><K><A><L><R><Q><K><Q><I><T><V><N><S><Q><K><A><E><A><S><L><R><V><K><G><G><D><K><I><F><I><N><D><K><F><N><L><P><V><K><Q><P><E><K><L><V><F><T><D><A><E><I><K><L><A><K><K><I><T><T><D><Y><L><I><Y><E><D><D><N><L><I><A><I><N><K><P><A><G><L... | Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.<BOP> | Q4UKQ3 |
P49524 | PETL_TRICV | Cytochrome b6-f complex subunit VI | Trieres | <M><T><I><A><I><D><Y><F><L><L><V><G><F><C><F><A><F><T><S><G><L><Y><L><G><L><K><S><I><K><L><I> | Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex... | P49524 |
Q8IZ81 | ELMD2_HUMAN | ELMO domain-containing protein 2 | Homo | <M><F><I><S><L><W><E><F><F><Y><G><H><F><F><R><F><W><M><K><W><L><L><R><Q><M><T><G><K><C><E><L><Q><R><I><F><D><T><Y><V><G><A><Q><R><T><H><R><I><E><N><S><L><T><Y><S><K><N><K><V><L><Q><K><A><T><H><V><V><Q><S><E><V><D><K><Y><V><D><D><I><M><K><E><K><N><I><N><P><E><K><D><A><S><F><K><I><C><M><K><M><C><L><L><Q><I><T><G><Y><K><Q... | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.<BOP> | Q8IZ81 |
Q0HLN0 | DNAK_SHESM | Heat shock protein 70 | Shewanella | <M><G><K><I><I><G><I><D><L><G><T><T><N><S><C><V><A><V><L><D><G><G><K><A><R><V><L><E><N><A><E><G><D><R><T><T><P><S><I><I><A><Y><T><D><D><E><T><I><V><G><Q><P><A><K><R><Q><A><V><T><N><P><N><N><T><F><F><A><I><K><R><L><I><G><R><R><F><K><D><D><E><V><Q><R><D><V><N><I><M><P><F><K><I><I><Q><A><D><N><G><D><A><W><V><E><S><R><G><N... | Acts as a chaperone.<BOP> | Q0HLN0 |
Q39V47 | SSRP_GEOMG | Small protein B | Geobacter | <M><G><E><K><L><I><C><N><N><K><K><A><F><H><D><Y><F><I><E><E><R><F><E><A><G><M><V><L><K><G><T><E><V><K><S><L><R><M><G><K><A><N><L><N><D><S><F><A><L><V><R><D><G><E><I><F><L><H><N><L><H><I><N><P><Y><D><F><G><N><R><Q><N><H><D><P><D><R><L><R><K><L><L><M><H><K><S><E><I><E><K><L><F><G><K><I><R><E><K><G><Y><S><V><V><P><L><R><L... | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | Q39V47 |
Q9BT49 | THAP7_HUMAN | THAP domain-containing protein 7 | Homo | <M><P><R><H><C><S><A><A><G><C><C><T><R><D><T><R><E><T><R><N><R><G><I><S><F><H><R><L><P><K><K><D><N><P><R><R><G><L><W><L><A><N><C><Q><R><L><D><P><S><G><Q><G><L><W><D><P><A><S><E><Y><I><Y><F><C><S><K><H><F><E><E><D><C><F><E><L><V><G><I><S><G><Y><H><R><L><K><E><G><A><V><P><T><I><F><E><S><F><S><K><L><R><R><T><T><K><T><K><G... | Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.<BOP> | Q9BT49 |
Q7ZYZ7 | PCGF1_DANRE | Polycomb group RING finger protein 1 | Danio | <M><A><E><Q><G><P><M><A><I><A><M><R><L><R><N><Q><L><Q><N><V><Y><K><L><D><P><L><R><N><E><E><E><V><K><I><K><I><K><D><L><N><E><H><I><V><C><Y><L><C><A><G><Y><F><I><D><A><T><T><I><T><E><C><L><H><T><F><C><K><S><C><I><V><K><Y><L><Q><T><S><K><Y><C><P><M><C><N><I><K><I><H><E><T><Q><P><L><L><N><L><K><L><D><R><V><M><Q><D><I><V><Y... | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histo... | Q7ZYZ7 |
P55004 | PHYE_IPONI | Phytochrome E | Ipomoea | <M><E><N><Y><G><K><A><V><T><F><S><S><S><A><T><S><N><L><N><T><G><K><A><I><A><Q><Y><N><A><D><A><K><L><M><A><E><F><E><Q><S><R><E><S><G><K><S><F><D><Y><S><R><S><V><I><H><A><P><Q><N><V><T><E><E><E><M><T><A><Y><L><S><R><I><Q><R><G><G><L><I><Q><P><F><G><C><M><L><A><I><E><E><P><S><F><K><I><V><G><F><S><E><N><C><F><D><L><L><G><L... | Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversi... | P55004 |
Q92ME6 | AROK_RHIME | Shikimate kinase | Sinorhizobium | <M><N><D><V><T><E><P><V><S><A><T><L><A><E><R><A><K><R><T><L><G><K><R><N><L><V><F><I><G><L><M><G><A><G><K><S><A><I><G><R><L><T><A><Q><A><L><G><V><P><F><V><D><S><D><H><E><I><E><R><V><S><R><M><T><V><S><D><L><F><A><T><Y><G><E><E><E><F><R><A><L><E><A><R><V><L><K><R><L><L><R><S><G><P><R><V><V><S><T><G><G><G><A><Y><I><N><E><R... | Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<BOP> | Q92ME6 |
P18207 | GLBL_TYLHE | Giant extracellular hemoglobin linker 1 chain | Tylorrhynchus | <G><A><L><G><D><R><N><G><D><C><A><C><D><R><P><S><P><R><G><Y><W><G><G><G><M><T><G><R><S><A><F><A><D><P><H><I><A><E><G><R><L><A><N><Q><D><A><R><L><G><T><L><E><E><E><V><D><K><L><Q><H><K><Y><D><D><F><I><A><G><K><T><A><R><R><E><R><F><A><Q><L><K><D><R><V><W><G><L><E><A><H><H><C><D><D><D><H><L><S><C><K><D><V><A><F><T><C><I><G... | Acts as a linker for the assembly of heme-containing chains in the construction of giant hemoglobin.<BOP> | P18207 |
B0XP71 | XYND_ASPFC | Xylobiase xlnD | Aspergillus subgen. Fumigati | <M><S><V><A><K><S><I><A><A><V><L><V><A><L><L><P><G><A><L><A><Q><A><N><T><S><Y><V><D><Y><N><V><E><A><N><P><N><L><T><P><Q><S><V><A><T><I><D><L><S><F><P><D><C><E><N><G><P><L><S><K><T><L><V><C><D><T><S><A><R><P><H><D><R><A><A><A><L><V><S><M><F><T><F><E><E><L><V><N><N><T><G><N><T><S><P><G><V><P><R><L><G><L><P><P><Y><Q><V><W... | Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.<BOP> | B0XP71 |
Q2H3I7 | SHO1_CHAGB | Osmosensor SHO1 | Chaetomium | <M><E><Y><S><R><P><Q><Y><G><R><K><R><M><S><L><G><N><I><I><G><D><P><F><A><L><A><T><T><S><I><A><T><L><A><W><L><I><S><F><V><A><T><I><I><A><H><I><Q><Y><P><V><K><F><P><L><F><A><Y><W><A><L><V><F><Y><F><G><L><I><I><G><V><F><V><V><V><A><S><D><S><T><Q><T><Y><H><V><A><L><V><G><Y><L><G><C><G><L><V><L><S><T><S><S><V><N><N><L><I><H... | Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.<BOP> | Q2H3I7 |
A1AWT6 | SYT_RUTMC | Threonyl-tRNA synthetase | Candidatus Ruthia | <M><P><I><I><T><L><P><D><G><T><Q><K><I><F><E><Q><V><V><S><V><T><Q><V><A><K><S><I><G><L><S><L><A><K><A><A><L><A><G><E><V><D><G><Q><L><V><D><T><S><F><L><I><K><T><D><A><N><L><A><I><I><T><A><N><D><D><K><G><L><E><I><I><R><H><S><T><A><H><L><L><A><Q><A><T><Q><M><L><Y><P><K><A><Q><V><T><I><G><P><V><I><D><N><G><F><Y><Y><D><F><V... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP> | A1AWT6 |
B0T872 | YIDC_CAUSK | Membrane protein YidC | unclassified Caulobacter | <M><Q><N><D><S><N><K><N><T><L><M><F><L><V><C><A><F><A><I><L><I><G><Y><Q><F><L><V><M><G><P><Q><Q><K><Q><R><E><A><E><L><R><A><K><K><A><A><E><A><Q><V><A><V><Q><P><G><M><T><I><G><A><D><G><T><P><Q><P><L><K><L><S><R><D><E><A><K><A><Q><S><P><R><I><A><V><D><T><P><A><L><S><G><S><I><A><L><K><G><A><R><I><D><D><L><W><L><K><R><Y><T... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | B0T872 |
Q0KA02 | DAPE_CUPNH | N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase | Cupriavidus | <M><T><A><T><L><A><L><T><E><D><L><I><R><R><R><S><V><T><P><A><D><E><G><C><Q><A><I><L><E><T><R><L><K><A><L><G><F><D><C><E><A><L><V><S><G><P><D><D><F><R><V><T><N><L><W><A><V><R><R><G><T><Q><G><K><D><G><K><L><L><V><F><A><G><H><T><D><V><V><P><T><G><P><L><E><Q><W><H><S><D><P><F><A><P><T><H><R><D><G><K><L><Y><G><R><G><A><A><D... | Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP> | Q0KA02 |
Q53B48 | 3SX7_OPHHA | Three-finger toxin | Ophiophagus | <M><K><N><L><L><L><T><F><L><V><V><T><I><V><C><L><D><L><G><Y><T><L><I><C><H><Q><V><H><G><L><Q><T><C><E><P><A><Q><K><F><C><Q><I><R><T><T><M><F><F><P><N><H><P><V><L><L><M><G><C><T><Y><N><C><P><T><E><R><Y><S><V><C><C><S><T><D><K><C><N><K> | This three-finger toxin binds and inhibits the nicotinic acetylcholine receptor (nAChR).<BOP> | Q53B48 |
A1JKK3 | RNC_YERE8 | Ribonuclease III | Yersinia | <M><N><P><I><V><I><N><R><L><Q><R><K><L><G><Y><T><F><Q><Q><Q><E><L><L><L><Q><A><L><T><H><R><S><A><S><S><K><H><N><E><R><L><E><F><L><G><D><S><I><L><S><F><V><I><A><N><E><L><Y><R><R><F><P><R><V><D><E><G><D><M><S><R><M><R><A><T><L><V><R><G><N><T><L><A><E><M><A><R><E><F><D><L><G><E><C><L><R><L><G><P><G><E><L><K><S><G><G><F><R... | Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.<B... | A1JKK3 |
A8LIT9 | NUOD_DINSH | NDH-1 subunit D | Dinoroseobacter | <M><M><D><G><T><N><F><D><D><A><L><T><G><E><Q><K><I><R><N><F><N><I><N><F><G><P><Q><H><P><A><A><H><G><V><L><R><L><V><L><E><L><D><G><E><I><V><E><R><C><D><P><H><I><G><L><L><H><R><G><T><E><K><L><M><E><S><R><T><Y><L><Q><N><L><P><Y><F><D><R><L><D><Y><V><A><P><M><N><Q><E><H><A><W><C><L><A><I><E><K><L><T><G><T><V><V><P><R><R><G... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | A8LIT9 |
A2RN27 | FMT_LACLM | Methionyl-tRNA formyltransferase | Lactococcus cremoris subsp. cremoris | <M><T><K><T><K><I><I><F><M><G><T><P><Q><F><A><A><T><V><L><K><G><L><I><D><S><N><K><Y><E><I><L><A><V><V><T><Q><P><D><R><K><V><G><R><K><Q><E><L><R><M><T><P><V><K><E><L><A><L><T><V><N><L><P><V><L><Q><P><E><K><L><S><G><S><V><E><M><T><Q><I><M><T><L><L><E><S><G><E><V><G><I><V><T><A><A><F><G><Q><F><L><P><G><K><L><L><V><V><A><R... | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP> | A2RN27 |
Q32LP2 | RADI_BOVIN | Radixin | Bos | <M><P><K><P><I><N><V><R><V><T><T><M><D><A><E><L><E><F><A><I><Q><P><N><T><T><G><K><Q><L><F><D><Q><V><V><K><T><V><G><L><R><E><V><W><F><F><G><L><Q><Y><V><D><S><K><G><Y><S><T><W><L><K><L><N><K><K><V><T><Q><Q><D><V><K><K><E><N><P><L><Q><F><K><F><R><A><K><F><F><P><E><D><V><S><E><E><L><I><Q><E><I><T><Q><R><L><F><F><L><Q><V><K... | Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.<BOP> | Q32LP2 |
Q9PDX7 | A2MG_XYLFA | Alpha-2-macroglobulin | Xylella | <M><R><D><R><V><A><M><M><L><R><P><L><V><R><G><W><I><P><R><A><V><L><L><L><T><V><A><F><S><F><G><C><N><R><N><H><N><G><Q><L><P><Q><S><S><G><E><P><V><A><V><A><K><E><P><V><K><G><F><V><L><V><R><A><Y><P><D><Q><H><D><G><E><L><A><L><A><L><E><F><S><Q><P><L><A><A><T><Q><E><F><D><T><L><V><R><L><E><Q><D><S><G><N><H><D><G><G><W><S><L... | Protects the bacterial cell from host peptidases.<BOP> | Q9PDX7 |
Q03QT1 | RIMP_LEVBA | Ribosome maturation factor RimP | Levilactobacillus | <M><S><T><V><V><E><T><V><T><A><L><A><Q><P><I><V><A><Q><H><Q><F><E><L><V><D><V><E><F><V><K><E><G><K><S><W><Y><L><R><L><Y><I><D><K><P><G><G><I><N><I><E><E><C><A><L><V><S><D><E><V><S><E><K><M><D><A><L><D><P><D><P><I><P><Q><A><Y><F><L><E><V><S><S><P><G><A><E><R><P><L><K><K><P><A><D><F><E><K><A><V><G><D><Y><I><H><V><S><L><Y... | Required for maturation of 30S ribosomal subunits.<BOP> | Q03QT1 |
Q65M01 | NSRR_BACLD | HTH-type transcriptional regulator NsrR | Bacillus | <M><K><L><T><N><Y><T><D><Y><S><L><R><V><L><I><F><L><A><T><K><N><S><N><E><L><V><N><I><K><D><I><A><D><S><Y><S><I><S><K><N><H><L><M><K><V><I><Y><E><L><G><K><L><G><Y><V><E><T><I><R><G><R><N><G><G><I><R><L><G><K><A><P><E><L><I><N><I><G><E><V><I><R><H><T><E><D><D><F><N><L><V><E><C><F><N><G><E><K><N><H><C><I><L><S><P><I><C><G... | Nitric oxide-responsive transcriptional regulator.<BOP> | Q65M01 |
P02804 | MT1_CRIGR | Metallothionein-I | Cricetulus | <M><D><P><N><C><S><C><S><T><G><S><T><C><T><C><S><S><S><C><G><C><K><D><C><K><C><T><S><C><K><K><S><C><C><S><C><C><P><V><G><C><S><K><C><A><Q><G><C><V><C><K><G><A><S><D><K><C><T><C><C><A> | Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.<BOP> | P02804 |
Q757F0 | COX9_ASHGO | Cytochrome c oxidase polypeptide VIIA | Eremothecium | <M><S><A><I><A><P><I><T><G><S><L><K><K><R><I><M><K><D><I><A><V><G><M><G><L><G><T><V><L><G><S><Y><W><W><W><G><F><H><K><P><K><I><A><A><R><E><N><Y><Y><T><Q><L><A><E><Q><K><A><A><E><E> | Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII... | Q757F0 |
Q1D764 | RL24_MYXXD | 50S ribosomal protein L24 | Myxococcus | <M><Q><K><L><K><V><G><D><T><I><Q><V><M><A><G><A><E><A><S><E><K><N><P><A><T><K><R><G><K><V><L><K><I><D><R><E><A><E><R><V><T><V><E><G><L><R><L><V><K><R><H><M><K><K><T><P><Q><S><P><E><G><G><I><V><E><K><P><G><T><I><A><L><A><N><V><Q><V><V><C><A><K><C><D><K><P><T><R><V><G><I><R><T><E><G><E><E><G><K><K><K><R><F><C><K><N><C><D... | One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP> | Q1D764 |
Q8PLY9 | MSRQ_XANAC | Flavocytochrome MsrQ | Xanthomonas | <M><A><K><T><S><T><S><V><I><A><A><K><T><L><V><H><A><A><A><L><A><P><I><A><L><L><G><W><Q><F><W><Q><V><W><Q><S><G><S><D><A><L><G><A><D><P><V><A><E><I><E><H><R><T><G><L><W><A><L><R><L><L><L><I><T><L><A><I><T><P><L><R><Q><L><T><G><Q><A><V><V><I><R><F><R><R><M><L><G><L><Y><A><F><F><Y><A><T><V><H><L><A><A><Y><L><T><L><D><L><R... | Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essentia... | Q8PLY9 |
A9CB34 | SFI1_PAPAN | Protein SFI1 homolog | Papio | <M><S><S><R><W><L><N><F><H><E><K><M><I><K><Q><R><M><E><K><K><V><D><S><R><Y><F><R><D><G><A><V><K><K><P><Y><S><A><K><T><L><S><N><K><K><S><S><A><S><F><G><I><R><R><E><L><P><S><T><S><H><L><V><Q><Y><R><G><T><H><T><C><T><R><Q><G><R><L><R><E><L><R><I><R><C><V><A><R><K><F><L><Y><L><W><I><R><M><T><F><G><R><V><F><P><S><K><A><R><F... | Plays a role in the dynamic structure of centrosome-associated contractile fibers via its interaction with CETN2.<BOP> | A9CB34 |
A8ZV69 | RL5_DESOH | 50S ribosomal protein L5 | Desulfosudis | <M><S><S><F><K><E><F><Y><T><T><E><V><V><P><K><L><Q><E><T><F><G><Y><K><N><V><M><Q><I><P><K><L><E><K><I><V><L><N><M><G><L><G><E><A><I><S><N><I><K><I><I><D><S><A><V><E><E><L><K><L><I><S><G><Q><Q><P><V><I><R><R><A><R><K><S><I><A><A><F><K><L><R><Q><G><M><P><V><G><C><M><V><T><L><R><H><E><R><M><Y><D><F><F><N><K><L><V><N><I><A... | This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement... | A8ZV69 |
A5FNE6 | LPXK_FLAJ1 | Lipid A 4'-kinase | Flavobacterium | <M><N><L><L><R><K><I><L><F><P><F><A><I><L><Y><G><L><I><T><S><I><R><N><F><L><F><D><K><G><I><L><K><S><T><S><F><D><L><P><V><I><A><V><G><N><L><S><V><G><G><T><G><K><T><P><Q><I><E><Y><L><I><R><L><L><S><N><K><Y><R><A><A><T><L><S><R><G><Y><K><R><K><S><E><G><F><V><L><A><D><E><N><S><N><A><E><I><L><G><D><E><P><F><Q><F><Y><Q><K><F... | Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).<BOP> | A5FNE6 |
B2A449 | PURA_NATTJ | IMP--aspartate ligase | Natranaerobius | <M><S><S><V><I><V><V><G><S><Q><W><G><D><E><G><K><G><K><V><T><D><Y><L><A><E><D><S><G><V><I><V><R><Y><Q><G><G><N><N><A><G><H><T><V><S><I><G><D><K><V><Y><K><L><H><L><I><P><S><G><I><F><H><G><N><K><T><C><V><L><G><N><G><M><V><I><D><P><K><S><L><I><E><E><L><E><Y><L><K><N><H><G><I><T><S><F><E><L><I><I><S><D><R><A><H><V><I><M><P... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | B2A449 |
B2RLM4 | KDSB_PORG3 | CMP-2-keto-3-deoxyoctulosonic acid synthase | Porphyromonas | <M><N><T><E><V><I><A><I><I><P><A><R><F><A><S><S><R><F><P><G><K><P><L><A><D><M><L><G><K><S><M><I><Q><R><V><H><E><R><I><A><G><V><V><P><R><A><V><V><A><T><D><D><E><R><I><R><Q><A><V><E><D><F><G><G><E><V><V><M><T><S><P><E><C><S><S><G><T><E><R><C><R><E><A><F><D><K><V><G><R><G><E><K><I><V><L><N><L><Q><G><D><E><P><F><I><Q><K><E... | Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.<BOP> | B2RLM4 |
Q6HCX2 | RNH3_BACHK | Ribonuclease HIII | Bacillus cereus group | <M><S><N><S><I><V><I><Q><T><N><S><T><V><I><E><D><M><K><Q><Q><Y><K><H><S><L><S><P><K><T><P><Q><G><G><I><F><M><A><K><V><P><S><C><T><I><T><A><Y><K><S><G><K><V><M><F><Q><G><G><R><A><E><A><E><A><A><R><W><Q><T><V><S><Q><T><P><K><T><A><V><K><K><S><V><D><S><H><R><Y><A><P><P><A><S><I><G><T><M><S><I><V><G><S><D><E><V><G><T><G><D... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q6HCX2 |
Q8A3C0 | COAD_BACTN | Pantetheine-phosphate adenylyltransferase | Bacteroides | <M><R><K><A><I><F><P><G><T><F><D><P><F><T><I><G><H><Y><S><V><V><E><R><A><L><T><F><M><D><E><I><I><I><G><I><G><I><N><E><N><K><N><T><Y><F><P><I><E><K><R><E><E><M><I><R><N><L><Y><K><D><N><P><R><I><K><V><M><S><Y><D><C><L><T><I><D><F><A><Q><Q><V><E><A><Q><F><I><V><R><G><I><R><T><V><K><D><F><E><Y><E><E><T><I><A><D><I><N><R><K... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | Q8A3C0 |
A0LZ02 | RL19_GRAFK | 50S ribosomal protein L19 | Gramella | <M><E><S><L><V><K><Y><V><Q><D><E><F><V><D><R><K><D><L><P><E><F><S><A><G><D><T><I><T><V><Y><Y><E><I><K><E><G><Q><K><T><R><T><Q><F><F><R><G><V><V><I><Q><K><R><G><T><G><S><S><Q><T><F><T><I><R><K><M><S><G><T><V><G><V><E><R><I><F><P><I><N><L><P><A><I><Q><K><I><E><I><N><K><K><G><S><V><R><R><A><R><I><F><Y><F><R><G><L><T><G><K... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | A0LZ02 |
Q6L135 | OTC_PICTO | Ornithine carbamoyltransferase | Picrophilus | <M><K><R><D><I><I><S><V><Y><D><M><K><D><D><L><E><D><I><I><E><L><S><I><K><L><K><K><D><R><T><I><K><F><S><E><K><K><I><L><A><M><I><F><E><K><P><S><T><R><T><R><N><S><L><E><V><A><M><E><Q><L><N><G><H><A><I><Y><L><N><P><N><D><M><Q><I><G><R><G><E><T><I><A><D><T><A><R><V><L><S><R><F><V><D><I><I><S><Y><R><A><F><N><H><D><D><V><V><E... | Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP> | Q6L135 |
Q9H4G0 | E41L1_HUMAN | Neuronal protein 4.1 | Homo | <M><T><T><E><T><G><P><D><S><E><V><K><K><A><Q><E><E><A><P><Q><Q><P><E><A><A><A><A><V><T><T><P><V><T><P><A><G><H><G><H><P><E><A><N><S><N><E><K><H><P><S><Q><Q><D><T><R><P><A><E><Q><S><L><D><M><E><E><K><D><Y><S><E><A><D><G><L><S><E><R><T><T><P><S><K><A><Q><K><S><P><Q><K><I><A><K><K><Y><K><S><A><I><C><R><V><T><L><L><D><A><S... | May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.<BOP> | Q9H4G0 |
Q9CDW9 | RL16_LACLA | 50S ribosomal protein L16 | Lactococcus | <M><L><V><P><K><R><V><K><H><R><R><E><F><R><G><K><M><R><G><Y><A><K><G><G><D><T><I><S><F><G><E><Y><G><L><Q><A><T><T><S><H><W><I><T><N><R><Q><I><E><A><A><R><I><A><M><T><R><Y><M><K><R><N><G><Q><V><W><I><K><I><F><P><H><K><S><Y><T><A><K><A><I><G><V><R><M><G><S><G><K><G><A><P><E><G><W><V><A><P><V><K><R><G><V><V><M><F><E><L><G... | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP> | Q9CDW9 |
A4WEQ9 | LSRG_ENT38 | Phospho-AI-2 isomerase | Enterobacter | <M><N><V><T><L><V><E><I><N><I><K><P><E><R><V><D><E><F><L><D><V><F><R><A><N><H><E><G><A><I><Q><E><P><G><N><L><R><F><D><V><L><Q><D><P><R><V><K><T><R><F><F><I><Y><E><A><Y><K><D><E><E><A><V><M><A><H><K><K><T><P><H><Y><L><A><C><V><D><K><L><E><A><L><M><S><E><P><R><K><K><R><C><F><V><G><L><M><P><E> | Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).<BOP> | A4WEQ9 |
Q9PKE2 | LGT_CHLMU | Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase | Chlamydia | <M><I><H><W><E><Q><S><R><T><L><L><S><F><P><Q><V><G><L><H><L><S><W><Y><G><I><F><F><S><L><G><I><F><L><S><S><F><A><G><I><R><L><A><T><V><L><C><K><D><P><N><M><R><K><E><L><K><T><G><L><E><N><F><A><L><G><A><L><L><V><I><V><I><G><A><R><A><F><Y><V><L><F><Y><G><G><S><F><Y><F><E><N><P><S><E><I><I><K><I><W><K><G><G><L><S><S><H><G><A... | Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP> | Q9PKE2 |
Q6F9R8 | PSRP_ACIAD | Pyruvate, water dikinase regulatory protein | Acinetobacter | <M><S><E><G><K><L><I><K><R><S><V><F><F><I><S><D><G><T><A><I><T><A><E><T><L><G><H><S><L><L><A><Q><F><P><N><V><D><F><D><I><H><I><M><P><Y><I><T><T><E><E><A><A><M><N><I><V><E><E><I><N><Q><C><Q><S><R><D><G><T><L><P><L><V><F><D><T><L><V><D><P><N><V><R><E><I><I><N><T><S><K><A><V><N><L><D><V><F><E><G><L><I><S><K><L><E><Q><V><L... | Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.<BOP> | Q6F9R8 |
A6W2U5 | HSLV_MARMS | ATP-dependent protease subunit HslV | Marinomonas | <M><T><T><I><L><T><V><R><K><G><N><Q><V><V><V><G><G><D><G><Q><V><S><L><G><N><T><V><M><K><G><N><A><R><K><V><R><R><L><Y><R><G><E><V><I><A><G><F><A><G><G><T><A><D><A><F><T><L><F><E><R><F><E><G><Q><L><E><K><H><Q><G><H><L><V><R><A><A><V><D><L><A><K><D><W><R><S><D><R><A><L><R><K><L><E><A><M><L><I><V><A><N><K><E><S><T><L><I><I... | Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.<BOP> | A6W2U5 |
Q5JI21 | APGM_THEKO | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Thermococcus | <M><K><K><R><K><G><L><L><I><I><L><D><G><L><G><D><R><P><I><K><E><F><G><G><K><T><P><L><E><Y><A><N><T><P><N><M><D><R><L><A><K><M><G><I><L><G><Q><Q><D><P><I><K><P><G><Q><P><A><G><S><D><T><A><H><L><S><I><F><G><Y><D><P><Y><K><V><Y><R><G><R><G><F><L><E><A><L><G><V><G><L><D><L><N><E><D><D><L><A><F><R><V><N><F><A><T><I><E><N><G... | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP> | Q5JI21 |
A0RPR5 | RL19_CAMFF | 50S ribosomal protein L19 | Campylobacter | <M><R><N><K><Y><I><E><A><F><E><N><A><Q><I><E><N><K><S><V><P><D><F><R><A><G><D><T><L><R><I><A><I><R><I><K><E><G><D><K><T><R><V><Q><N><F><E><G><I><C><I><A><R><R><G><S><G><S><G><E><T><F><I><I><R><K><I><G><A><N><S><V><G><V><E><R><I><F><P><I><Y><S><E><S><L><E><S><I><T><V><L><R><R><G><R><I><R><R><S><K><L><F><Y><L><R><D><R><R... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | A0RPR5 |
Q96P56 | CTSR2_HUMAN | Cation channel sperm-associated protein 2 | Homo | <M><A><A><Y><Q><Q><E><E><Q><M><Q><L><P><R><A><D><A><I><R><S><R><L><I><D><T><F><S><L><I><E><H><L><Q><G><L><S><Q><A><V><P><R><H><T><I><R><E><L><L><D><P><S><R><Q><K><K><L><V><L><G><D><Q><H><Q><L><V><R><F><S><I><K><P><Q><R><I><E><Q><I><S><H><A><Q><R><L><L><S><R><L><H><V><R><C><S><Q><R><P><P><L><S><L><W><A><G><W><V><L><E><C... | Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte.<BOP> | Q96P56 |
Q9MI64 | CYB_LIPVE | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Lipotes | <M><T><N><I><R><K><T><H><P><L><M><K><I><L><N><K><T><F><I><D><L><P><T><P><S><N><I><S><S><W><W><N><F><G><S><L><L><G><L><C><L><T><V><Q><I><L><T><G><L><F><L><A><M><H><Y><T><P><D><T><S><T><A><F><S><S><I><T><H><I><C><R><D><V><N><Y><G><W><M><I><R><H><L><H><A><N><G><A><S><M><F><F><I><C><L><Y><I><H><I><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q9MI64 |
C0MBC3 | XERS_STRE4 | Tyrosine recombinase XerS | Streptococcus | <M><K><R><D><L><L><L><T><K><I><E><E><Y><K><N><I><M><P><W><Y><V><L><D><Y><Y><Q><S><K><L><S><V><P><Y><S><F><T><T><L><Y><E><Y><L><K><E><Y><K><R><F><F><E><W><L><I><D><S><D><L><S><K><A><A><R><I><A><D><V><D><L><T><T><L><E><H><L><S><K><K><D><M><E><A><F><I><L><Y><L><R><E><R><P><S><L><N><I><Y><S><T><K><K><G><V><S><Q><T><T><I><N... | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.<BOP> | C0MBC3 |
Q977V3 | SECY_HALVD | Protein transport protein SEC61 subunit alpha homolog | Haloferax | <M><G><W><K><D><A><A><E><P><V><L><S><R><M><P><A><V><A><R><P><E><G><H><V><P><F><R><R><K><L><G><W><T><G><G><I><L><V><L><Y><F><F><L><T><N><V><T><L><F><G><L><D><A><A><T><A><N><D><L><F><G><Q><F><R><S><I><L><A><G><Q><Q><G><S><V><L><Q><L><G><I><G><P><I><V><T><A><S><I><V><L><Q><L><L><G><G><A><D><L><L><G><L><D><T><D><N><N><P><R... | The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydr... | Q977V3 |
Q8RCY5 | TDXH1_CALS4 | Thioredoxin-dependent peroxiredoxin 1 | Caldanaerobacter | <M><K><L><L><G><E><K><F><P><S><M><E><V><M><T><T><H><G><V><K><R><L><P><E><D><Y><A><G><K><W><F><V><L><F><S><H><P><A><D><F><T><P><V><C><T><T><E><F><V><E><F><A><R><K><A><E><E><F><K><Q><L><N><T><E><L><I><G><L><S><V><D><Q><V><F><S><H><I><K><W><V><E><W><I><K><D><N><T><G><V><Q><I><P><F><P><V><I><A><D><E><L><G><R><V><S><N><Q><L... | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP> | Q8RCY5 |
Q1GIN9 | NUOD_RUEST | NDH-1 subunit D | unclassified Ruegeria | <M><D><G><S><K><F><D><D><A><Q><T><G><E><Q><K><I><R><N><F><N><I><N><F><G><P><Q><H><P><A><A><H><G><V><L><R><L><V><L><E><L><D><G><E><I><V><E><R><C><D><P><H><I><G><L><L><H><R><G><T><E><K><L><M><E><S><R><T><Y><L><Q><N><L><P><Y><F><D><R><L><D><Y><V><A><P><M><N><Q><E><H><A><W><C><L><A><I><E><K><L><T><G><V><E><V><P><R><R><A><Q... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q1GIN9 |
Q6L046 | FOLD_PICTO | Methenyltetrahydrofolate cyclohydrolase | Picrophilus | <M><I><I><D><G><V><K><I><S><E><T><K><M><E><R><L><K><N><E><I><E><K><I><K><N><T><G><I><N><P><K><M><K><I><I><L><I><G><N><D><Y><G><S><V><V><Y><S><K><A><K><M><R><R><G><S><K><L><G><I><D><V><D><L><D><R><Y><D><S><I><S><R><E><D><L><I><K><L><L><K><R><Y><S><Q><S><D><D><I><H><G><I><M><I><E><T><P><V><P><G><I><N><Y><Y><D><V><V><N><E... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q6L046 |
Q27YU0 | RSP1_CHLRE | Flagellar radial spoke protein 1 | Chlamydomonas | <M><A><L><G><P><F><V><L><P><F><R><G><D><Q><Y><S><F><G><I><N><F><K><S><S><P><E><E><K><L><N><F><D><L><S><C><V><A><F><D><V><K><G><Q><L><H><D><T><L><H><A><R><K><P><T><A><L><D><G><A><L><V><K><G><F><E><K><Q><A><L><P><E><E><T><V><Q><V><E><G><D><D><V><I><Y><M><F><P><K><K><F><E><R><Q><V><E><V><L><L><F><V><A><S><A><P><S><I><P><G... | Flagellar radial spokes contribute to the regulation of dynein arm activity and thus the pattern of flagellar bending. They consist of a thin stalk, which is attached to the a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from ... | Q27YU0 |
Q634V6 | GCST_BACCZ | Glycine cleavage system T protein | Bacillus cereus group | <M><I><T><L><Q><R><T><P><L><F><D><V><Y><A><K><Y><G><G><K><T><I><D><F><G><G><W><E><L><P><V><Q><F><S><S><I><K><E><E><H><E><A><V><R><T><A><A><G><L><F><D><V><S><H><M><G><E><V><E><V><K><G><V><D><S><L><A><F><L><Q><R><V><V><T><N><D><V><S><T><L><K><V><G><G><A><Q><Y><T><A><M><C><Y><E><N><G><G><T><V><D><D><L><L><I><Y><K><R><G><E... | The glycine cleavage system catalyzes the degradation of glycine.<BOP> | Q634V6 |
Q325P7 | FRSA_SHIBS | Esterase FrsA | Shigella | <M><T><Q><A><N><L><S><E><T><L><F><K><P><R><F><K><H><P><E><T><S><T><L><V><R><R><F><N><H><G><A><Q><P><P><V><Q><S><A><L><D><G><K><T><I><P><H><W><Y><R><M><I><N><R><L><M><W><I><W><R><G><I><D><P><R><E><I><L><D><V><Q><A><R><I><V><M><S><D><A><E><R><T><D><D><D><L><Y><D><T><V><I><G><Y><R><G><G><N><W><I><Y><E><W><A><T><Q><A><M><V... | Catalyzes the hydrolysis of esters.<BOP> | Q325P7 |
Q88YK7 | PSTB2_LACPL | Phosphate-transporting ATPase 2 | Lactiplantibacillus | <M><S><T><I><L><T><T><E><N><L><S><L><F><Y><G><K><K><E><A><L><K><G><I><N><I><D><F><D><D><K><G><I><T><A><L><I><G><P><S><G><C><G><K><S><T><F><L><R><C><L><N><R><M><N><D><L><I><P><N><V><T><I><T><G><E><V><N><F><N><G><H><N><I><Y><A><P><T><T><D><T><V><Q><L><R><K><E><I><G><M><V><F><Q><Q><P><N><P><F><P><F><S><I><Y><E><N><V><I><Y... | Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q88YK7 |
B1MX68 | PROA_LEUCK | Glutamyl-gamma-semialdehyde dehydrogenase | Leuconostoc | <M><V><V><S><V><Q><E><I><G><Q><R><A><K><T><A><A><T><D><V><A><G><L><T><I><T><T><R><N><D><L><L><R><Q><M><S><Q><A><L><L><D><N><Q><S><A><I><M><A><A><N><K><E><D><I><A><A><Y><A><N><T><L><S><Q><P><M><I><K><R><L><T><L><D><Q><P><T><I><K><A><I><A><T><S><L><L><A><V><V><A><L><P><D><P><L><A><G><P><F><D><T><W><Q><T><H><V><D><L><K><I... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP> | B1MX68 |
Q9CHF9 | ACP_LACLA | Acyl carrier protein | Lactococcus | <M><A><V><F><E><K><V><Q><D><I><I><V><D><E><L><G><K><E><K><E><E><V><T><L><E><T><S><F><E><E><L><D><A><D><S><L><D><L><F><Q><I><I><N><D><I><E><D><E><F><D><V><E><V><D><T><E><A><D><M><K><T><V><A><D><L><V><K><Y><V><E><N><N><K> | Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP> | Q9CHF9 |
B2K3M9 | ISPH_YERPB | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | Yersinia | <M><Q><I><L><L><A><N><P><R><G><F><C><A><G><V><D><R><A><I><S><I><V><E><R><A><I><E><M><Y><G><A><P><I><Y><V><R><H><E><V><V><H><N><R><Y><V><V><E><S><L><C><E><R><G><A><I><F><I><E><E><I><S><E><V><P><D><G><S><I><L><I><F><S><A><H><G><V><S><Q><A><V><R><A><E><A><R><S><R><N><L><T><M><L><F><D><A><T><C><P><L><V><T><K><V><H><M><E><V... | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.<BOP> | B2K3M9 |
Q7NTK9 | IHFB_CHRVO | Integration host factor subunit beta | Chromobacterium | <M><T><K><S><E><L><I><A><R><L><S><E><R><L><A><E><R><N><S><Q><L><V><Y><K><D><A><E><L><A><V><K><T><I><L><D><A><M><A><N><N><L><A><Q><G><S><R><I><E><I><R><G><F><G><S><F><D><L><N><Y><R><P><P><R><V><G><R><N><P><K><S><G><A><S><V><S><V><P><E><K><Y><V><P><H><F><K><A><G><K><E><L><R><E><R><V><D><L><S><L><L><E><Q><T><Q><A> | This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP> | Q7NTK9 |
A9L8T6 | RHDF1_PAPAN | Rhomboid family member 1 | Papio | <M><S><E><A><R><R><D><S><T><S><S><L><Q><R><K><K><P><P><W><L><K><L><D><I><P><S><A><V><P><P><T><A><E><E><P><S><F><L><Q><P><L><R><R><Q><A><F><L><R><S><V><S><M><P><A><E><T><A><H><I><S><S><P><H><H><E><L><R><R><S><V><L><Q><R><Q><T><S><I><T><Q><T><I><R><R><G><T><A><D><W><F><G><V><S><K><D><S><D><S><T><Q><K><W><Q><R><K><S><I><R... | Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.<BOP> | A9L8T6 |
B7UFZ9 | FADI_ECO27 | Fatty acid oxidation complex subunit beta | Escherichia | <M><G><Q><V><L><P><L><V><T><R><Q><G><D><R><I><A><I><V><S><G><L><R><T><P><F><A><R><Q><A><T><A><F><H><G><I><P><A><G><D><L><G><K><M><V><V><G><E><L><L><A><R><T><E><I><P><A><E><V><I><E><Q><L><V><F><G><Q><V><V><Q><M><P><E><A><P><N><I><A><R><E><I><V><L><G><T><G><M><N><V><H><T><D><A><Y><S><V><S><R><A><C><A><T><S><F><Q><A><V><A... | Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.<BOP> | B7UFZ9 |
Q8TD46 | MO2R1_HUMAN | Cell surface glycoprotein OX2 receptor 1 | Homo | <M><L><C><P><W><R><T><A><N><L><G><L><L><L><I><L><T><I><F><L><V><A><A><S><S><S><L><C><M><D><E><K><Q><I><T><Q><N><Y><S><K><V><L><A><E><V><N><T><S><W><P><V><K><M><A><T><N><A><V><L><C><C><P><P><I><A><L><R><N><L><I><I><I><T><W><E><I><I><L><R><G><Q><P><S><C><T><K><A><Y><K><K><E><T><N><E><T><K><E><T><N><C><T><D><E><R><I><T><W... | Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinit... | Q8TD46 |
Q28MG0 | GLMU_JANSC | Glucosamine-1-phosphate N-acetyltransferase | unclassified Jannaschia | <M><Q><A><T><P><R><P><L><A><L><I><V><L><A><A><G><A><G><T><R><M><N><S><D><L><P><K><P><L><H><T><L><G><S><A><P><L><V><A><H><T><I><A><A><G><A><S><L><E><P><A><R><L><V><V><I><T><G><H><G><A><D><E><V><E><A><V><L><Q><D><I><A><P><E><A><V><T><A><R><Q><T><P><Q><L><G><T><G><H><A><V><L><Q><A><A><A><A><L><E><G><F><E><G><D><A><M><V><L... | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ... | Q28MG0 |
O51236 | PSTB_BORBU | Phosphate-transporting ATPase | Borreliella | <M><I><K><E><K><D><T><P><K><N><E><V><I><I><E><T><E><N><L><N><L><F><Y><T><D><F><K><A><L><N><K><I><N><M><K><I><L><K><N><S><I><T><A><L><I><G><P><S><G><C><G><K><S><T><F><L><R><T><L><N><R><M><N><D><L><V><E><G><I><K><I><E><G><N><V><I><Y><E><G><K><N><I><Y><S><N><N><F><D><I><L><E><L><R><R><K><I><G><M><V><F><Q><T><P><N><P><F><L... | Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.<BOP> | O51236 |
Q8K305 | NSL1_MOUSE | Kinetochore-associated protein NSL1 homolog | Mus | <M><A><A><V><S><E><T><V><L><V><S><A><P><Q><D><H><D><A><Q><A><A><S><D><P><Q><A><T><A><A><D><S><P><L><E><D><F><R><V><R><C><T><L><K><R><A><V><M><E><V><M><E><M><C><G><R><F><V><Q><E><L><G><A><V><L><P><E><D><V><R><E><L><A><L><R><D><A><Q><W><T><F><E><S><A><V><Q><E><N><V><S><F><N><G><Q><A><W><E><E><A><K><E><H><G><L><M><D><S><D... | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.<BOP> | Q8K305 |
A1UD94 | NUOK_MYCSK | NDH-1 subunit K | unclassified Mycobacterium | <M><N><P><D><N><Y><L><H><L><S><A><L><L><F><T><I><G><A><A><G><V><L><L><R><R><N><V><I><V><V><F><M><C><V><E><L><M><L><N><A><A><N><L><A><F><V><A><F><S><R><M><H><G><Q><L><D><G><Q><V><V><A><F><F><T><M><V><V><A><A><C><E><V><V><I><G><L><A><I><I><M><T><I><Y><R><A><R><R><S><A><S><V><D><D><A><N><L><L><K><H> | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar... | A1UD94 |
A1UTX8 | CH10_BARBK | Chaperonin-10 | Bartonella | <M><A><N><T><K><F><R><P><L><H><D><R><V><V><V><R><R><V><E><S><E><N><K><T><A><G><G><I><I><I><P><D><T><A><Q><E><K><P><Q><E><G><E><V><I><A><V><G><N><G><V><L><N><D><N><G><Q><R><V><S><L><E><V><K><E><G><D><R><I><L><F><G><K><W><S><G><T><E><V><K><I><N><G><E><E><L><L><I><M><K><E><S><D><I><M><G><I><L><A> | Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ... | A1UTX8 |
Q7NA81 | RAVA_PHOLL | Regulatory ATPase variant A | Photorhabdus | <M><V><R><I><M><L><L><A><E><K><I><V><C><L><S><H><Y><L><E><S><G><L><Y><E><R><Q><Q><T><I><R><L><C><L><L><A><A><L><C><G><E><S><V><F><L><L><G><P><P><G><I><A><K><S><L><I><A><R><R><L><K><F><A><F><R><D><A><R><A><F><E><Y><L><M><T><R><F><S><T><P><E><E><I><F><G><P><L><S><I><Q><A><L><K><E><E><G><R><Y><Q><R><L><T><N><G><Y><L><P><E... | Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone.<BOP> | Q7NA81 |
B0UWF2 | MNMA_HISS2 | tRNA-specific 2-thiouridylase MnmA | Histophilus | <M><K><S><I><V><Y><E><K><K><L><P><K><L><T><A><L><E><I><A><K><N><S><K><K><K><V><I><C><G><M><S><G><G><V><D><S><S><V><S><A><F><I><L><Q><Q><Q><G><Y><Q><V><E><G><L><F><M><K><N><W><E><E><D><D><D><T><D><Y><C><T><A><A><N><D><L><A><D><A><Q><A><V><C><D><K><L><G><I><K><L><H><K><I><N><F><A><A><E><Y><W><D><N><V><F><E><H><F><L><A><E... | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP> | B0UWF2 |
C0H3X4 | YEZG_BACSU | Immunity protein YezG | Bacillus | <M><Q><D><L><Y><Q><L><I><G><E><K><L><N><D><I><I><P><G><E><W><T><K><I><Y><L><Y><A><E><V><L><D><D><S><T><M><V><L><F><H><F><R><T><P><E><N><N><Q><I><I><Y><S><Q><D><I><P><S><H><Y><N><V><S><K><D><I><F><K><T><L><L><R><E><L><R><E><L><F><E><E><L><R><T><E><H><R><N><N><N><D><D><V><W><T><N><L><T><L><T><L><D><R><S><G><E><F><Q><L><D... | Immunity component of one of 6 LXG toxin-immunity modules in this strain. They promote kin selection, mediate competition in biofilms, and drive spatial segregation of different strains, indicating that LXG toxins may help avoid warfare between strains in biofilms. Mediates intercellular competition during biofilm form... | C0H3X4 |
Q89ZI8 | PURNU_BACTN | S-methyl-5'-thioadenosine phosphorylase BT_4389 | Bacteroides | <M><I><S><I><T><K><D><K><R><M><L><G><Y><E><S><L><S><S><Y><S><N><I><S><H><F><V><T><T><R><Q><G><G><C><S><E><G><N><Y><A><S><F><N><C><T><P><Y><S><G><D><E><A><E><K><V><R><R><N><Q><T><L><L><M><E><G><M><S><Q><I><P><E><E><L><V><I><P><V><Q><T><H><E><T><N><Y><L><L><I><G><D><A><Y><L><S><A><S><S><Q><Q><R><Q><E><M><L><H><G><V><D><A... | Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has ade... | Q89ZI8 |
O67564 | RL18_AQUAE | 50S ribosomal protein L18 | Aquifex | <M><P><R><L><K><T><R><R><E><K><R><L><R><R><H><K><R><I><R><K><K><V><F><G><T><P><E><R><P><R><L><C><V><Y><R><S><L><K><H><F><Y><A><Q><I><I><D><D><T><I><G><H><T><L><V><S><A><S><T><L><D><P><E><F><E><K><I><T><G><K><R><G><G><K><S><I><K><D><A><E><V><V><A><E><I><I><A><R><R><A><L><E><K><G><I><K><K><V><V><F><D><R><G><G><F><K><Y><H... | This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP> | O67564 |
B8E9D5 | HSCB_SHEB2 | Co-chaperone protein HscB homolog | Shewanella | <M><N><Y><F><E><L><F><K><F><S><P><A><F><D><I><D><T><A><L><L><A><E><R><Y><R><E><L><Q><R><A><V><H><P><D><K><F><A><N><D><T><E><Q><Q><K><L><L><S><V><Q><R><T><A><Q><V><N><D><G><F><Q><T><L><K><D><P><I><R><R><A><E><H><M><L><S><L><R><G><I><E><L><S><H><E><T><T><T><V><K><D><T><G><F><L><M><Q><Q><M><E><W><R><E><A><L><E><D><I><R><D... | Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.<BOP> | B8E9D5 |
P09620 | KEX1_YEAST | Killer expression defective protein 1 | Saccharomyces | <M><F><Y><N><R><W><L><G><T><W><L><A><M><S><A><L><I><R><I><S><V><S><L><P><S><S><E><E><Y><K><V><A><Y><E><L><L><P><G><L><S><E><V><P><D><P><S><N><I><P><Q><M><H><A><G><H><I><P><L><R><S><E><D><A><D><E><Q><D><S><S><D><L><E><Y><F><F><W><K><F><T><N><N><D><S><N><G><N><V><D><R><P><L><I><I><W><L><N><G><G><P><G><C><S><S><M><D><G><A... | Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from the precursors of K1, K2 and K28 killer toxins and a-factor (mating pheromone). Involved in the programmed cell death caused by defective N-glycosylation and contributes also to the active cel... | P09620 |
C5C0J2 | RS10_BEUC1 | 30S ribosomal protein S10 | Beutenbergia | <M><A><G><Q><K><I><R><I><R><L><K><S><Y><D><H><E><V><I><D><S><S><A><R><K><I><V><D><T><V><T><R><A><G><A><T><V><V><G><P><V><P><L><P><T><E><K><N><V><F><C><V><I><R><S><P><H><K><Y><K><D><S><R><D><H><F><E><M><R><T><H><K><R><L><I><D><I><I><D><P><T><P><K><A><V><D><S><L><M><R><L><D><L><P><A><D><V><N><I><E><I><K><L> | Involved in the binding of tRNA to the ribosomes.<BOP> | C5C0J2 |
B8NSP6 | PFF1_ASPFN | FXNA-related family protease 1 | Aspergillus subgen. Circumdati | <M><A><S><L><R><L><P><R><A><N><P><L><A><F><T><R><W><P><V><T><V><I><T><A><I><V><Y><L><A><L><L><I><P><L><L><V><V><H><H><V><V><P><S><A><P><S><S><P><P><S><G><L><N><I><S><E><A><W><A><D><L><Q><V><L><T><N><G><F><H><P><Y><N><S><R><R><N><D><V><I><H><S><W><L><L><R><R><I><N><E><I><L><D><S><T><P><L><E><Q><E><Y><R><A><L><D><E><E><K... | May be involved in vacuolar sorting and osmoregulation.<BOP> | B8NSP6 |
P02001 | HBAD_CHICK | Hemoglobin alpha-D chain | Gallus | <M><L><T><A><E><D><K><K><L><I><Q><Q><A><W><E><K><A><A><S><H><Q><E><E><F><G><A><E><A><L><T><R><M><F><T><T><Y><P><Q><T><K><T><Y><F><P><H><F><D><L><S><P><G><S><D><Q><V><R><G><H><G><K><K><V><L><G><A><L><G><N><A><V><K><N><V><D><N><L><S><Q><A><M><A><E><L><S><N><L><H><A><Y><N><L><R><V><D><P><V><N><F><K><L><L><S><Q><C><I><Q><V... | Involved in oxygen transport from the lung to the various peripheral tissues.<BOP> | P02001 |
C3KVF0 | LDH_CLOB6 | L-lactate dehydrogenase | Clostridium | <M><I><K><K><R><N><T><T><K><I><S><V><I><G><A><G><S><V><G><A><T><T><A><Y><A><L><M><L><S><G><V><A><T><E><I><V><L><V><D><V><N><K><A><K><T><E><G><E><A><M><D><L><S><H><G><A><D><F><V><Q><P><V><N><I><L><S><G><D><Y><K><D><T><E><S><S><D><I><V><V><I><T><A><G><A><A><Q><K><V><G><E><T><R><L><Q><L><I><N><K><N><I><N><I><F><K><S><I><I... | Catalyzes the conversion of lactate to pyruvate.<BOP> | C3KVF0 |
Q3E798 | MIM2_YEAST | Mitochondrial import protein 2 | Saccharomyces | <M><A><D><S><E><D><T><S><V><I><L><Q><G><I><D><T><I><N><S><V><E><G><L><E><E><D><G><Y><L><S><D><E><D><T><S><L><S><N><E><L><A><D><A><Q><R><Q><W><E><E><S><L><Q><Q><L><N><K><L><L><N><W><V><L><L><P><L><L><G><K><Y><I><G><R><R><M><A><K><T><L><W><S><R><F><I><E><H><F><V> | Component of the MIM complex required for outer membrane protein import . Involved in import of the subset of proteins with multiple alpha-helical transmembrane segments, including UGO1, TOM20 and FZO1 .<BOP> | Q3E798 |
Q4ZM83 | GLYA2_PSEU2 | Serine hydroxymethyltransferase 2 | Pseudomonas syringae | <M><F><S><K><Q><D><Q><I><Q><G><Y><D><D><A><L><L><S><A><M><N><A><E><E><Q><R><Q><E><D><H><I><E><L><I><A><S><E><N><Y><T><S><K><R><V><M><Q><A><Q><G><S><G><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><H><V><D><K><V><E><Q><L><A><I><E><R><A><R><Q><L><F><G><A><D><Y><A><N><V><Q><P><H><S><G><S><Q><A><N><A><A><V><Y><L... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | Q4ZM83 |
A4SUW1 | RL3_POLAQ | 50S ribosomal protein L3 | Polynucleobacter | <M><S><L><G><L><I><G><R><K><V><G><M><T><R><L><F><T><D><E><G><D><S><I><P><V><T><V><I><D><V><S><D><N><R><I><A><Q><I><K><T><Q><A><T><D><G><Y><D><A><I><Q><L><A><H><G><T><R><R><A><T><R><V><T><K><A><M><A><G><H><F><A><K><A><G><V><M><A><G><N><G><L><N><E><F><Q><L><D><A><A><K><I><A><E><M><T><P><G><Q><V><I><P><A><D><T><A><F><T><A... | One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP> | A4SUW1 |
P22188 | MURE_ECOLI | UDP-N-acetylmuramyl-tripeptide synthetase | Escherichia | <M><A><D><R><N><L><R><D><L><L><A><P><W><V><P><D><A><P><S><R><A><L><R><E><M><T><L><D><S><R><V><A><A><A><G><D><L><F><V><A><V><V><G><H><Q><A><D><G><R><R><Y><I><P><Q><A><I><A><Q><G><V><A><A><I><I><A><E><A><K><D><E><A><T><D><G><E><I><R><E><M><H><G><V><P><V><I><Y><L><S><Q><L><N><E><R><L><S><A><L><A><G><R><F><Y><H><E><P><S><D... | Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analogs as substrates, although much less efficiently, but not L-lysine.<BOP> | P22188 |
P63678 | ATPB_MYCBO | F-ATPase subunit beta | Mycobacterium tuberculosis complex | <M><T><T><T><A><E><K><T><D><R><P><G><K><P><G><S><S><D><T><S><G><R><V><V><R><V><T><G><P><V><V><D><V><E><F><P><R><G><S><I><P><E><L><F><N><A><L><H><A><E><I><T><F><E><S><L><A><K><T><L><T><L><E><V><A><Q><H><L><G><D><N><L><V><R><T><I><S><L><Q><P><T><D><G><L><V><R><G><V><E><V><I><D><T><G><R><S><I><S><V><P><V><G><E><G><V><K><G... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP> | P63678 |
P14961 | RBS_OLILU | Ribulose bisphosphate carboxylase small subunit | Olisthodiscus | <M><R><L><T><Q><G><A><F><S><Y><L><P><D><L><T><D><A><Q><I><I><K><Q><I><D><Y><C><L><S><R><G><W><S><V><G><V><E><W><T><D><D><P><H><P><R><N><A><Y><W><E><L><W><G><L><P><L><F><D><V><K><D><S><S><A><I><L><Y><E><V><N><E><C><R><R><L><N><P><E><G><Y><I><K><L><V><A><F><N><A><A><R><G><T><E><S><S><A><S><A><F><I><V><Q><R><P><K><S><E><P... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Although the s... | P14961 |
P55351 | HPNC_SINFN | Hydroxysqualene synthase | Sinorhizobium | <M><T><S><G><S><G><P><R><S><D><A><M><H><R><E><K><N><F><P><V><A><S><W><I><I><H><P><R><H><R><A><L><I><L><A><F><Y><R><F><V><R><M><A><D><D><I><A><D><H><A><T><L><A><P><D><E><K><L><L><Y><L><D><L><L><E><A><E><L><L><G><K><G><E><T><R><A><E><A><V><H><L><R><T><A><L><D><R><R><G><M><P><P><R><H><A><L><D><L><L><T><A><F><R><M><D><V><T... | Involved in the biosynthesis of the hopanoid precursor squalene (SQ) from farnesyl diphosphate (FPP). Catalyzes the second step, the conversion of presqualene diphosphate (PSPP) to hydroxysqualene (HSQ).<BOP> | P55351 |
Q97BA1 | PRIL_THEVO | DNA primase large subunit PriL | Thermoplasma | <M><R><F><P><P><L><L><F><F><Q><D><S><E><A><V><K><R><I><A><N><S><V><R><G><T><K><D><D><D><A><E><I><K><D><H><S><M><R><F><I><R><N><A><I><S><G><D><Q><Q><K><E><I><L><N><V><D><M><L><R><Y><I><A><W><V><L><V><A><L><N><E><N><I><V><T><A><R><T><V><I><R><E><R><D><A><V><E><D><A><L><K><N><Q><Q><P><E><D><I><E><N><F><A><D><D><L><K><I><N... | Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymeras... | Q97BA1 |
A5UQR2 | MOAC_ROSS1 | Molybdenum cofactor biosynthesis protein C | Roseiflexus | <M><S><D><L><T><H><L><D><E><S><G><R><A><R><M><V><D><V><G><A><K><D><D><T><L><R><E><A><V><A><R><G><E><V><R><M><R><P><E><T><L><Q><R><L><A><A><G><D><M><P><K><G><D><V><L><A><T><A><R><I><A><G><I><M><A><A><K><R><A><P><D><L><I><P><L><C><H><P><L><L><L><T><H><V><A><V><D><A><R><L><D><V><A><T><S><T><V><Q><I><E><A><T><V><R><T><V><G... | Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).<BOP> | A5UQR2 |
A9VU81 | BSHC_BACMK | Putative cysteine ligase BshC | Bacillus cereus group | <M><E><I><K><E><I><S><V><P><L><Q><G><V><V><A><D><Y><M><N><G><K><K><E><I><Q><S><C><F><D><Y><L><L><T><E><D><A><F><K><Q><R><L><H><D><L><R><E><R><E><F><F><R><Q><D><L><V><T><H><L><L><E><Y><N><T><Q><L><Q><A><G><E><F><T><I><Q><N><I><K><A><L><E><D><E><N><T><Y><V><V><I><A><G><Q><Q><A><G><L><L><T><G><P><L><Y><T><V><H><K><I><I><S... | Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.<BOP> | A9VU81 |
P0DG68 | UDG_STRP3 | UDP-glucose 6-dehydrogenase | Streptococcus | <M><K><I><A><V><A><G><S><G><Y><V><G><L><S><L><G><V><L><L><S><L><Q><N><E><V><T><I><V><D><I><L><P><S><K><V><D><K><I><N><N><G><L><S><P><I><Q><D><E><Y><I><E><Y><Y><L><K><S><K><Q><L><S><I><K><A><T><L><D><S><K><A><A><Y><K><E><A><E><L><V><I><I><A><T><P><T><N><Y><N><S><R><I><N><Y><F><D><T><Q><H><V><E><T><V><I><K><E><V><L><S><V... | Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis.<BOP> | P0DG68 |
P25756 | MNMG_PSEPU | Glucose-inhibited division protein A | Pseudomonas | <M><D><F><P><S><R><F><D><V><I><V><I><G><G><G><H><A><G><T><E><A><A><L><A><S><A><R><M><G><V><K><T><L><L><L><T><H><N><V><E><T><L><G><H><M><S><C><N><P><A><I><G><G><I><G><K><S><H><L><V><K><E><I><D><A><L><G><G><A><M><A><L><A><T><D><K><S><G><I><Q><F><R><V><L><N><N><R><K><G><P><A><V><R><A><T><R><A><Q><A><D><R><A><I><Y><K><A><V... | NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP> | P25756 |
A7FCT2 | DUT_YERP3 | dUTP pyrophosphatase | Yersinia | <M><K><K><I><D><I><K><I><L><D><P><R><V><G><N><E><F><P><L><P><T><Y><A><T><E><G><S><A><G><L><D><L><R><A><C><L><D><H><A><V><E><L><Q><P><G><Q><T><T><L><L><P><T><G><L><A><I><H><I><G><D><S><A><L><A><A><V><I><L><P><R><S><G><L><G><H><K><H><G><I><V><L><G><N><L><V><G><L><I><D><S><D><Y><Q><G><Q><L><M><V><S><V><W><N><R><G><Q><Q><P... | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP> | A7FCT2 |
A4WL16 | SUCC_PYRAR | Succinyl-CoA synthetase subunit beta | Pyrobaculum | <M><K><L><H><E><Y><E><A><K><E><L><F><S><K><Y><G><V><K><I><P><P><G><R><V><A><T><T><P><E><E><V><R><K><I><A><E><E><I><G><G><P><V><V><L><K><A><Q><V><V><V><A><G><R><G><K><A><G><G><I><K><V><A><K><T><P><E><E><A><Y><E><L><A><T><K><M><F><G><M><N><I><K><G><L><V><V><K><K><I><Y><V><T><K><Y><V><E><V><E><R><E><M><Y><L><S><L><I><I><D... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | A4WL16 |
Q5F4W4 | YIDD_NEIG1 | Putative membrane protein insertion efficiency factor | Neisseria | <M><N><F><L><L><S><K><L><L><L><G><L><I><R><F><Y><Q><Y><C><I><S><P><L><I><P><P><R><C><R><Y><T><P><T><C><S><Q><Y><A><V><E><A><V><K><K><Y><G><A><F><K><G><L><R><L><A><I><K><R><I><A><R><C><H><P><F><G><G><H><G><H><D><P><V><P> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | Q5F4W4 |
A7I2V7 | DXS_CAMHC | 1-deoxyxylulose-5-phosphate synthase | Campylobacter | <M><D><I><K><N><K><N><L><T><E><L><N><E><L><C><K><Q><I><R><E><R><I><L><E><V><V><S><Q><N><G><G><H><L><S><S><N><M><G><A><V><E><L><I><V><A><M><H><Y><V><F><D><P><D><S><D><P><F><I><F><D><V><S><H><Q><S><Y><A><H><K><L><L><T><G><R><W><D><E><F><S><S><L><R><Q><L><G><G><I><S><G><Y><T><K><P><K><E><S><K><F><D><Y><F><V><A><G><H><S><S... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | A7I2V7 |
Q8G340 | PNCB_BRUSU | Nicotinate phosphoribosyltransferase | Brucella | <M><A><K><T><D><L><A><R><R><V><Y><N><H><T><W><K><L><D><P><I><I><R><S><L><L><D><T><D><F><Y><K><L><L><M><L><Q><M><I><W><G><L><Y><P><R><V><D><A><T><F><S><L><I><N><R><T><S><S><V><R><L><A><D><E><I><D><E><G><E><L><R><A><Q><L><D><H><A><R><T><L><R><F><S><K><K><E><M><I><W><L><A><G><N><T><F><Y><G><R><K><Q><I><F><Q><P><E><F><L><A... | Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.<BOP> | Q8G340 |
Q2W158 | PLSY_MAGSA | Lysophosphatidic acid synthase | Magnetospirillum | <M><L><E><L><V><A><A><T><L><G><G><Y><L><L><G><S><V><P><F><G><L><V><L><T><R><L><A><G><L><G><D><I><R><Q><I><G><S><G><N><I><G><A><T><N><V><L><R><T><G><R><K><G><L><A><L><A><T><L><L><L><D><G><G><K><G><A><I><A><V><G><L><V><W><V><L><L><G><R><E><M><V><P><V><A><G><F><A><A><V><L><G><H><N><F><P><V><W><L><G><F><K><G><G><K><G><V><A... | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP> | Q2W158 |
Q92GH4 | END3_RICCN | DNA-(apurinic or apyrimidinic site) lyase | spotted fever group | <M><Q><A><Q><I><V><N><K><I><F><E><I><F><S><K><N><N><P><N><P><K><T><E><L><I><Y><K><N><D><F><T><L><L><V><A><V><I><L><S><A><Q><A><T><D><I><S><V><N><L><A><T><K><S><L><F><A><T><Y><D><T><P><E><K><I><L><E><L><G><E><E><G><L><K><K><Y><I><K><S><I><G><L><F><N><S><K><A><K><N><I><I><A><L><C><K><I><L><I><S><N><Y><Q><A><S><V><P><N><D... | DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-... | Q92GH4 |
Q95QJ7 | GPR1_CAEEL | G-protein regulator 1 | Caenorhabditis | <M><D><V><S><Y><Y><D><G><P><K><D><E><V><A><E><A><M><L><K><S><A><V><T><A><M><R><L><G><Q><Y><E><D><G><K><G><R><L><E><E><I><M><E><F><G><T><S><N><F><Q><L><L><G><T><I><Y><M><Y><Y><G><R><V><C><R><H><L><N><H><D><A><K><A><L><E><F><F><E><H><E><L><N><M><F><K><L><I><F><N><Y><P><E><A><C><D><S><T><R><R><I><V><E><Q><A><L><K><M><G><K... | In the 1-cell embryo, probably together with gpr-2, controls nuclear rotation and spindle elongation during mitosis . Complex of gpr-1 and gpr-2, in association with lin-5, activates G-protein signaling to affect mitotic spindle force . Polarity determinants (par genes) may regulate lin-5/gpr-1/gpr-2/goa-1 locally to c... | Q95QJ7 |
Q5YYX9 | MURG_NOCFA | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase | Nocardia | <M><E><E><Y><E><V><T><T><K><D><S><G><S><G><L><S><V><I><V><A><G><G><G><T><A><G><H><I><E><P><A><L><A><V><A><D><A><L><R><R><L><D><P><A><I><R><V><T><A><L><G><T><E><R><G><L><E><T><R><L><V><P><E><R><G><Y><P><L><E><L><I><P><P><V><P><L><P><R><K><P><T><V><D><L><L><R><L><P><A><R><V><R><A><S><V><R><R><T><R><A><V><I><D><A><V><Q><A... | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP> | Q5YYX9 |
Q606P5 | SYS_METCA | Seryl-tRNA(Ser/Sec) synthetase | Methylococcus | <M><L><D><P><R><L><F><R><T><Q><L><E><E><T><A><R><Q><L><G><R><R><G><F><V><L><D><T><A><A><F><G><A><L><E><E><R><R><K><A><L><Q><V><E><T><Q><N><L><Q><N><E><R><N><S><R><S><R><S><I><G><Q><A><K><A><R><G><E><D><I><E><P><L><L><A><A><V><Q><G><L><G><E><R><L><K><E><N><E><A><E><L><A><S><I><Q><E><R><M><E><A><L><L><L><G><V><P><N><L><L... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP> | Q606P5 |
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