accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q48MQ6 | RUTC_PSE14 | 3-aminoacrylate deaminase RutC | Pseudomonas | <M><T><K><K><A><I><I><P><A><G><T><T><K><P><I><A><P><F><V><P><G><S><M><A><D><G><V><L><Y><V><S><G><T><L><P><F><D><K><D><N><N><V><V><H><V><G><D><A><T><A><Q><T><R><H><V><L><E><T><I><K><S><V><V><E><T><A><G><G><T><M><D><D><V><T><F><N><M><I><M><I><R><D><W><A><D><Y><A><K><V><N><E><V><Y><A><E><Y><F><A><G><E><K><P><A><R><Y><C><I... | Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.<BOP> | Q48MQ6 |
Q8AVG9 | GATA_XENLA | Glutaminyl-tRNA synthase-like protein 1 | Xenopus | <M><L><G><M><S><L><R><E><A><A><A><V><L><R><L><G><Q><V><K><P><T><E><L><C><Q><K><C><L><S><L><I><K><E><T><S><F><L><N><A><Y><I><T><I><T><E><D><I><A><L><K><Q><A><A><E><A><D><K><R><F><A><Q><G><K><P><L><G><E><L><D><G><I><P><I><A><I><K><D><N><F><S><T><A><G><I><E><T><T><C><A><S><R><M><L><K><G><Y><V><A><P><Y><N><A><T><V><V><Q><K... | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP> | Q8AVG9 |
Q5AZQ6 | SPC24_EMENI | Probable kinetochore protein spc24 | Aspergillus subgen. Nidulantes | <M><L><L><D><E><N><P><S><T><L><I><H><H><T><I><G><N><F><N><I><A><P><D><K><Q><A><V><S><R><I><N><D><S><L><A><T><L><Q><Q><S><R><E><L><R><M><R><E><A><E><S><S><L><R><K><L><S><R><H><L><Q><S><L><S><T><Q><H><E><E><A><V><A><A><H><D><A><S><K><H><A><A><A><M><V><E><L><D><T><K><K><F><R><I><A><K><A><A><S><E><L><E><I><E><S><E><R><L><E... | Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.<BOP> | Q5AZQ6 |
Q2A1U9 | MSBA_FRATH | Lipid A export ATP-binding/permease protein MsbA | Francisella | <M><A><N><M><I><D><K><I><D><L><K><S><Q><G><S><S><N><L><S><G><E><M><T><N><H><Q><K><V><G><T><L><Y><K><R><L><L><L><Q><V><K><H><L><W><H><F><L><L><L><A><A><I><G><S><I><F><F><S><A><A><D><A><S><M><I><Y><L><I><N><P><I><L><N><Y><G><F><G><P><G><G><G><I><T><K><Q><S><A><T><I><L><M><L><M><G><V><G><M><V><G><L><L><A><L><R><S><V><G><S... | Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.<BOP> | Q2A1U9 |
Q8K4I4 | BPIA1_RAT | Palate lung and nasal epithelium clone protein | Rattus | <M><F><L><V><G><S><L><V><V><L><C><G><L><L><A><Q><S><T><A><Q><L><A><G><L><P><L><P><L><G><Q><G><L><P><L><P><L><G><Q><G><L><P><L><P><L><G><Q><G><L><P><L><A><V><S><P><A><L><P><S><N><P><T><D><L><L><A><G><N><F><A><N><A><L><S><G><G><L><L><S><G><G><L><L><G><I><L><E><N><I><P><L><L><D><V><I><K><S><G><G><G><S><S><N><G><L><V><G><G... | Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative ba... | Q8K4I4 |
Q4QLJ9 | CCMA_HAEI8 | Heme exporter protein A | Haemophilus | <M><F><E><Q><H><K><L><S><L><Q><N><L><S><C><Q><R><G><E><R><V><L><F><R><A><L><T><C><D><F><N><S><G><D><F><V><Q><I><E><G><H><N><G><I><G><K><T><S><L><L><R><I><L><A><G><L><A><Q><P><L><E><G><E><V><R><W><D><A><E><A><I><S><K><Q><R><E><Q><Y><H><Q><N><L><L><Y><L><G><H><L><L><G><V><K><P><E><L><T><A><W><E><N><L><Q><F><Y><Q><R><I><S... | Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.<BOP> | Q4QLJ9 |
B1ZZW8 | GLYA_OPITP | Serine hydroxymethyltransferase | Opitutus | <M><L><N><A><S><P><L><Q><T><L><D><P><Q><V><F><S><A><I><S><E><E><L><A><R><Q><Q><S><H><I><E><L><I><A><S><E><N><F><T><Y><P><A><V><M><E><A><Q><G><S><V><L><T><N><K><Y><A><E><G><Y><P><A><K><R><W><Y><G><G><C><E><F><V><D><K><V><E><V><L><A><I><E><R><A><K><K><L><F><G><A><E><H><A><N><V><Q><P><H><S><G><A><Q><A><N><T><A><V><Y><A><A... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | B1ZZW8 |
B3QWI1 | HEM3_CHLT3 | Pre-uroporphyrinogen synthase | Chloroherpeton | <M><K><K><A><L><I><I><G><T><R><S><S><P><L><A><L><W><Q><A><E><F><I><K><A><E><L><S><K><H><Y><P><S><L><D><I><S><L><R><H><I><K><T><T><G><D><K><I><L><D><A><P><L><A><K><I><G><D><K><G><L><F><T><R><E><I><E><H><V><M><L><R><N><E><I><D><L><A><V><H><S><L><K><D><L><P><T><E><T><P><E><G><L><V><I><T><A><I><T><E><R><E><D><N><R><D><V><L... | Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP> | B3QWI1 |
A3N007 | TRUB_ACTP2 | tRNA-uridine isomerase | Actinobacillus | <M><S><R><P><R><K><K><G><R><D><V><H><G><V><F><L><L><D><K><P><Q><G><M><S><S><N><D><I><L><Q><K><V><K><R><L><F><Q><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><F><L><L><D><S><D><K><R><Y><Q><V><T><A><K><L><G><K><R><T><D><T><S><D><A><E><G><Q><V><V><E><T><R><A><V><N><V><G><E><A><E... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | A3N007 |
P0C1M0 | ATPG_MAIZE | Inceptin | Zea | <M><S><C><S><H><L><S><T><A><W><S><S><S><A><L><A><S><S><A><S><T><T><R><R><R><S><P><P><R><S><G><L><L><V><R><C><S><L><R><E><L><R><T><R><I><D><S><V><R><N><T><Q><K><I><T><E><A><M><K><L><V><A><A><A><K><V><R><R><A><Q><E><A><V><V><S><S><R><P><F><S><E><A><L><V><E><V><L><Y><N><M><N><Q><E><I><Q><T><E><D><I><D><L><P><L><T><R><T><R... | Inceptin is a proteolytic fragment produced by insect larvae that previously ingested the protein. This peptide mediate plant perception of herbivory through the induction of volatile, phenylpropanoid and protease inhibitor defenses such as ethylene, jasmonic acid and salicylic acid for example.<BOP> | P0C1M0 |
Q9M8T9 | MCC1_ARATH | Protein MEIOTIC CONTROL OF CROSSOVERS 1 | Arabidopsis | <M><S><R><F><P><R><R><F><I><D><D><S><S><M><E><D><A><G><I><S><L><C><P><S><I><H><Y><R><P><I><N><P><N><D><L><D><R><L><E><Q><I><H><R><D><I><F><P><I><K><Y><E><S><E><F><F><Q><S><V><V><N><G><V><D><I><V><S><W><A><A><V><D><R><S><R><P><D><D><H><S><D><E><L><I><G><F><V><T><A><K><F><V><L><A><K><D><S><E><I><D><D><L><I><H><Y><D><S><S... | Histone acetyltransferase that probably regulates acetylation status of histone H3 during meiosis. Histone acetylation may influence recombination and chromosome segregation.<BOP> | Q9M8T9 |
O65621 | CADH6_ARATH | Cinnamyl alcohol dehydrogenase-like protein A | Arabidopsis | <M><E><R><L><S><G><E><K><E><Q><S><V><E><A><F><G><W><A><A><R><D><S><S><G><H><L><S><P><F><V><F><S><R><R><K><T><G><E><E><E><V><R><V><K><V><L><Y><C><G><I><C><H><S><D><L><H><C><L><K><N><E><W><H><S><S><I><Y><P><L><V><P><G><H><E><I><I><G><E><V><S><E><I><G><N><K><V><S><K><F><N><L><G><D><K><V><G><V><G><C><I><V><D><S><C><R><T><C... | Involved in lignin biosynthesis. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcohols.<BOP> | O65621 |
A8ZXG7 | HIS1_DESOH | ATP phosphoribosyltransferase | Desulfosudis | <M><T><Q><V><L><K><F><G><I><P><K><G><S><L><Q><D><A><T><I><A><L><F><K><R><C><G><W><K><I><N><V><N><G><R><S><Y><F><P><D><I><N><D><P><D><I><S><C><A><L><L><R><A><Q><E><M><A><R><N><V><E><H><G><T><L><D><A><G><L><T><G><K><D><W><I><A><E><N><N><S><D><V><H><V><V><A><D><L><V><Y><S><K><A><S><A><R><P><A><R><W><V><I><A><V><A><K><D><S... | Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.<BOP> | A8ZXG7 |
P18333 | SIGA_CHLTR | Sigma-A | Chlamydia | <M><R><M><D><T><L><D><S><Q><A><A><E><A><A><Q><E><E><E><I><Q><R><K><L><E><E><L><V><T><L><A><K><D><Q><G><F><I><T><Y><E><E><I><N><E><I><L><P><P><S><F><D><T><P><E><Q><I><D><Q><V><L><I><F><L><A><G><M><D><V><Q><V><L><N><Q><A><D><V><E><R><Q><K><E><R><K><K><E><A><K><E><L><E><G><L><A><K><R><S><E><G><T><P><D><D><P><V><R><M><Y><L... | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.<BOP> | P18333 |
Q8QZR1 | ATTY_MOUSE | L-tyrosine:2-oxoglutarate aminotransferase | Mus | <M><D><S><Y><V><I><Q><T><N><V><N><D><S><L><P><S><V><L><D><V><R><V><N><I><G><G><R><S><S><V><Q><G><R><A><K><G><R><K><A><R><W><N><V><R><P><S><D><M><S><N><K><T><F><N><P><I><R><A><I><V><D><N><M><K><V><K><P><N><P><N><K><T><V><I><S><L><S><I><G><D><P><T><V><F><G><N><L><P><T><D><P><E><V><T><Q><A><M><K><D><A><L><D><S><G><K><Y><N... | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity for phenylalanine.<BOP> | Q8QZR1 |
Q92BK1 | MNMA_LISIN | tRNA-specific 2-thiouridylase MnmA | Listeria | <M><S><T><N><N><S><D><I><R><V><V><V><G><M><S><G><G><V><D><S><S><V><T><A><H><I><L><K><E><Q><G><Y><D><V><I><G><I><F><M><K><N><W><D><D><T><D><E><F><G><V><C><T><A><T><E><D><Y><D><D><V><I><R><V><A><N><Q><I><G><I><P><Y><Y><A><V><N><F><E><K><E><Y><W><D><K><V><F><T><Y><F><L><D><E><Y><K><L><G><R><T><P><N><P><D><V><M><C><N><K><E... | Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP> | Q92BK1 |
B7UJQ9 | TIG_ECO27 | PPIase | Escherichia | <M><Q><V><S><V><E><T><T><Q><G><L><G><R><R><V><T><I><T><I><A><A><D><S><I><E><T><A><V><K><S><E><L><V><N><V><A><K><K><V><R><I><D><G><F><R><K><G><K><V><P><M><N><I><V><A><Q><R><Y><G><A><S><V><R><Q><D><V><L><G><D><L><M><S><R><N><F><I><D><A><I><I><K><E><K><I><N><P><A><G><A><P><T><Y><V><P><G><E><Y><K><L><G><E><D><F><T><Y><S><V... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | B7UJQ9 |
A7FP80 | SELA_YERP3 | Selenocysteinyl-tRNA(Sec) synthase | Yersinia | <M><S><A><E><P><H><P><L><Y><R><Q><L><P><A><I><D><R><L><L><N><E><P><E><M><A><P><L><L><A><E><Y><G><P><V><L><L><A><D><T><L><R><Q><L><Q><A><E><A><R><E><Y><I><G><Q><F><H><T><L><A><D><W><C><A><D><W><P><A><A><L><R><Q><R><L><N><Q><R><Q><P><A><L><K><P><V><F><N><L><T><G><T><V><L><H><T><N><L><G><R><A><P><L><A><E><S><A><I><A><A><V... | Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.<BOP> | A7FP80 |
Q164G2 | PDXA_ROSDO | 4-(phosphohydroxy)-L-threonine dehydrogenase | Roseobacter | <M><S><P><A><T><A><P><V><L><I><S><C><G><E><P><A><G><I><G><P><E><I><A><V><A><A><W><D><A><L><Q><G><T><I><P><L><A><W><V><G><D><P><R><H><L><P><A><S><T><T><F><T><A><I><T><H><P><R><A><V><A><D><V><P><T><G><S><L><P><V><L><V><H><D><F><A><A><P><S><T><P><G><H><P><D><P><A><N><A><Q><G><V><I><D><V><I><A><A><C><V><A><W><V><Q><E><G><A... | Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).<BOP> | Q164G2 |
Q3V4Y3 | PSAC_ACOCL | PsaC | Acorus | <M><S><H><S><V><K><I><Y><D><T><C><I><G><C><T><Q><C><V><R><A><C><P><T><D><V><L><E><M><I><P><W><D><G><C><K><A><K><Q><I><A><S><A><P><R><T><E><D><C><V><G><C><K><R><C><E><S><A><C><P><T><D><F><L><S><V><R><V><Y><L><G><N><E><T><T><R><S><M><G><L><P><Y> | Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity. FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin. The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex. Required for binding of PsaD and PsaE t... | Q3V4Y3 |
A2VDS1 | SCLY_BOVIN | Selenocysteine lyase | Bos | <M><E><A><A><G><A><R><N><R><D><A><R><S><R><A><E><K><S><P><P><E><S><R><K><V><Y><M><D><Y><N><A><T><T><P><L><E><P><E><V><I><E><A><M><T><E><A><M><R><E><A><W><G><N><P><S><S><S><Y><P><A><G><R><K><A><K><E><I><I><N><T><A><R><E><N><L><A><K><M><I><G><G><Q><P><Q><D><V><I><F><T><S><G><G><T><E><S><N><N><L><V><I><Q><S><V><V><K><H><F... | Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.<BOP> | A2VDS1 |
Q9V557 | CP4P2_DROME | CYPIVP2 | Sophophora | <M><M><I><C><L><L><W><I><S><V><A><I><L><V><V><I><H><W><I><Y><K><V><N><K><D><Y><N><I><L><A><F><F><A><R><R><V><Q><T><K><D><G><K><P><L><D><S><L><V><P><M><I><K><G><R><T><V><F><A><N><C><F><D><L><L><G><K><D><T><D><Q><V><F><T><H><L><R><Q><L><A><K><N><S><G><D><S><Y><L><Q><Y><S><M><G><F><S><N><F><N><V><I><D><A><H><N><A><A><N><I... | May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.<BOP> | Q9V557 |
A3DFC2 | MNTP_ACET2 | Putative manganese efflux pump MntP | Acetivibrio | <M><S><S><I><E><L><L><I><I><A><V><G><L><S><M><D><A><F><A><V><A><I><C><K><G><L><S><M><K><K><M><S><Y><R><N><A><V><L><T><G><C><F><F><G><G><F><Q><A><L><M><P><L><L><G><Y><L><L><G><T><Q><F><K><D><Y><I><T><S><I><D><H><W><I><A><F><G><L><L><S><L><I><G><I><N><M><I><K><E><S><K><N><T><C><E><I><T><D><E><D><D><T><F><S><L><K><S><L><T... | Probably functions as a manganese efflux pump.<BOP> | A3DFC2 |
P57876 | OTC_PASMU | Ornithine carbamoyltransferase | Pasteurella | <M><P><L><N><L><R><H><R><H><F><L><R><L><M><D><F><T><P><T><E><I><Q><F><L><L><D><L><S><A><N><L><K><K><A><K><Y><T><G><T><E><Q><P><R><L><K><G><K><N><I><A><L><I><F><E><K><T><S><T><R><T><R><C><S><F><E><V><A><A><Y><D><Q><G><A><N><V><T><Y><I><G><P><S><G><S><Q><I><G><H><K><E><S><M><K><D><T><A><R><V><L><G><R><M><Y><D><G><I><Q><Y... | Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP> | P57876 |
A8MKS2 | YIDD_ALKOO | Putative membrane protein insertion efficiency factor | Alkaliphilus | <M><S><R><L><C><I><F><L><I><Q><I><Y><R><K><Y><I><S><P><L><K><R><P><S><C><R><F><H><P><T><C><S><A><Y><S><M><A><A><Y><E><R><Y><G><F><F><K><G><T><Y><L><T><L><K><R><I><L><K><C><H><P><F><H><P><G><G><Y><D><P><L><R> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | A8MKS2 |
P61538 | RUVB_TREDE | Holliday junction ATP-dependent DNA helicase RuvB | Treponema | <M><S><D><D><F><E><V><V><R><P><E><E><Q><A><G><D><E><K><D><R><D><L><R><P><R><S><L><V><D><F><Q><G><Q><T><K><A><K><E><N><L><S><V><F><I><K><A><A><R><E><R><G><E><S><L><D><H><L><F><L><I><G><P><P><G><L><G><K><T><T><L><A><Q><I><T><A><N><E><L><G><V><D><F><K><V><T><G><A><P><A><L><D><K><P><K><D><L><A><G><I><L><T><T><L><T><E><R><S... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP> | P61538 |
Q0A6J9 | MRAY_ALKEH | UDP-MurNAc-pentapeptide phosphotransferase | Alkalilimnicola | <M><L><Y><H><L><A><M><A><L><E><G><V><Y><S><G><F><N><V><F><Q><Y><L><T><F><R><T><I><L><G><V><L><T><A><L><G><I><A><L><L><V><G><P><A><V><I><Q><R><L><V><E><H><Q><I><G><Q><Q><V><R><D><D><G><P><Q><S><H><L><S><K><A><G><T><P><T><M><G><G><A><L><I><L><V><A><I><A><V><A><T><L><L><W><S><D><L><T><N><R><Y><V><W><V><V><L><L><T><T><L><A... | Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I... | Q0A6J9 |
Q1H411 | PYRD_METFK | Dihydroorotate oxidase | Methylobacillus | <M><L><Y><S><I><V><K><P><W><L><F><R><L><D><A><E><R><A><H><D><F><T><L><K><N><L><K><R><L><E><R><S><G><L><L><N><L><Y><P><R><P><P><K><C><K><Q><R><Q><V><M><G><I><N><F><P><N><P><V><G><L><A><A><G><L><D><K><N><G><A><Y><I><D><A><L><A><G><L><G><F><G><F><I><E><I><G><T><I><T><P><R><P><Q><P><G><N><P><K><P><R><M><F><R><L><P><E><A><Q... | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP> | Q1H411 |
A7H4H5 | MSRA_CAMJD | Peptide-methionine (S)-S-oxide reductase | Campylobacter | <M><K><N><I><V><L><G><G><G><C><F><W><C><V><E><A><V><F><E><R><L><K><G><V><I><D><T><E><V><G><Y><S><G><G><N><P><N><P><S><Y><E><S><V><C><N><G><D><G><N><I><E><V><V><K><I><N><Y><D><E><K><Q><I><P><L><L><E><I><L><T><L><F><F><K><I><H><D><P><T><S><I><D><K><Q><G><A><D><I><G><I><Q><Y><R><S><I><I><F><Y><E><N><E><E><D><K><I><L><A><Q... | Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.<BOP> | A7H4H5 |
Q7YD13 | CYB_LONMO | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Lonchophylla | <M><T><N><I><R><K><T><H><P><L><L><K><I><L><N><N><S><F><V><D><L><P><A><P><S><S><L><S><A><W><W><N><F><G><S><L><L><G><V><C><L><T><L><Q><I><L><T><G><L><F><L><A><M><H><Y><T><A><D><T><A><T><A><F><N><S><V><A><H><I><C><R><D><V><N><Y><G><W><L><L><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><Y><L><H><V><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q7YD13 |
Q2J340 | HIS6_RHOP2 | ImGP synthase subunit HisF | Rhodopseudomonas | <M><F><K><V><R><V><I><P><C><L><D><V><K><D><G><R><V><V><K><G><V><N><F><V><D><L><R><D><A><G><D><P><V><E><A><A><I><A><Y><D><A><A><G><A><D><E><L><C><F><L><D><I><T><A><T><H><E><N><R><G><I><M><L><D><V><V><R><R><T><A><E><A><C><F><M><P><V><T><V><G><G><G><V><R><T><V><D><D><I><K><T><L><L><R><S><G><A><D><K><V><S><I><N><S><A><A><V... | IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.<BOP> | Q2J340 |
Q4ZWZ4 | PURT_PSEU2 | Phosphoribosylglycinamide formyltransferase 2 | Pseudomonas syringae | <M><T><Q><I><G><T><P><L><S><P><T><A><T><R><V><L><F><C><G><S><G><E><L><G><K><E><V><V><I><E><L><Q><R><L><G><V><E><V><I><A><V><D><R><Y><E><N><A><P><A><M><Q><V><A><H><R><S><H><V><I><N><M><L><D><G><A><A><L><R><A><V><I><E><A><E><K><P><H><F><I><V><P><E><I><E><A><I><A><T><A><T><L><V><E><L><E><A><E><G><F><T><V><I><P><T><A><R><A... | Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP> | Q4ZWZ4 |
A4ST05 | RL4_AERS4 | 50S ribosomal protein L4 | Aeromonas | <M><E><L><V><M><K><D><A><K><S><A><L><E><V><S><E><T><T><F><G><R><E><F><N><E><A><L><V><H><Q><V><V><V><A><Y><A><A><G><A><R><Q><G><T><R><A><Q><L><T><R><S><E><V><S><G><G><G><K><K><P><W><R><Q><K><G><T><G><R><A><R><A><G><S><I><R><S><P><I><W><R><S><G><G><V><T><F><A><A><K><P><Q><D><H><S><Q><K><V><N><K><K><M><Y><R><G><A><I><R><S... | Forms part of the polypeptide exit tunnel.<BOP> | A4ST05 |
Q7UJK7 | NDK_RHOBA | Nucleoside-2-P kinase | Rhodopirellula | <M><Q><R><T><L><V><L><L><K><P><D><C><V><Q><R><R><L><I><G><D><V><L><S><R><F><E><A><K><G><L><H><I><V><A><M><K><L><L><Q><V><T><P><E><L><S><K><Q><H><Y><A><E><H><V><E><K><P><F><Y><P><S><L><E><E><F><I><T><S><A><P><V><V><A><I><A><L><E><G><L><E><V><I><R><V><V><R><D><M><L><G><A><T><N><G><L><Q><A><A><P><G><T><L><R><G><D><Y><S><S... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP> | Q7UJK7 |
Q28147 | PP1R8_BOVIN | Protein phosphatase 1 regulatory inhibitor subunit 8 | Bos | <M><A><A><A><A><N><S><G><S><S><L><P><L><F><D><C><P><T><W><A><G><K><P><P><P><G><L><H><L><D><V><V><K><G><D><K><L><I><E><K><L><I><I><D><E><K><K><Y><Y><L><F><G><R><N><P><D><L><C><D><F><T><I><D><H><Q><S><C><S><R><V><H><A><A><L><V><Y><H><K><H><L><K><R><V><F><L><I><D><L><N><S><T><H><G><T><F><L><G><H><I><R><L><E><P><H><K><P><Q... | Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation.<BOP> | Q28147 |
Q2YT97 | DTD_STAAB | Gly-tRNA(Ala) deacylase | Staphylococcus | <M><K><V><V><V><Q><R><V><K><E><A><S><V><T><N><D><T><L><N><N><Q><I><K><K><G><Y><C><L><L><V><G><I><G><Q><D><S><T><E><Q><D><A><D><V><I><A><K><K><I><A><N><A><R><L><F><E><D><D><N><N><K><L><N><F><N><I><Q><Q><V><N><G><E><I><L><S><V><S><Q><F><T><L><Y><A><D><V><K><K><G><N><R><P><G><F><S><N><S><K><N><P><D><Q><A><V><K><I><Y><E><Y... | An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec... | Q2YT97 |
Q63764 | AZIN1_RAT | Ornithine decarboxylase antizyme inhibitor | Rattus | <M><K><G><F><I><D><D><A><N><Y><S><V><G><L><L><D><E><G><T><N><L><G><N><V><I><D><N><Y><V><Y><E><H><T><L><T><G><K><N><A><F><F><V><G><D><L><G><K><I><V><K><K><H><S><Q><W><Q><N><V><V><A><Q><I><K><P><F><Y><M><V><K><C><N><S><T><P><A><V><L><E><I><L><A><A><L><G><T><G><F><A><C><S><T><K><N><E><M><A><L><V><Q><E><L><G><V><S><P><E><N... | Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizy... | Q63764 |
Q8FP63 | RNH2_COREF | Ribonuclease HII | Corynebacterium | <M><A><T><I><R><R><L><K><Q><L><R><T><Y><E><V><A><L><S><R><H><G><L><G><P><V><A><G><V><D><E><A><G><R><G><A><C><C><G><P><I><S><I><A><A><C><I><L><P><D><R><P><I><A><D><L><A><V><L><T><D><S><K><Q><L><S><P><P><V><R><A><R><L><M><P><L><V><K><K><H><A><V><A><W><S><V><I><H><I><S><A><A><D><I><D><R><F><G><I><Q><H><A><N><I><S><G><M><R... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q8FP63 |
B8H8V7 | AROC_PSECP | 5-enolpyruvylshikimate-3-phosphate phospholyase | Pseudarthrobacter | <M><L><R><W><L><T><A><G><E><S><H><G><P><A><L><M><G><I><I><E><G><V><P><A><G><V><E><I><T><S><G><H><I><A><D><S><L><A><R><R><R><L><G><Y><G><R><G><A><R><M><K><F><E><Q><D><V><V><T><I><L><G><G><V><R><H><G><V><T><Q><G><G><P><V><A><V><Q><V><G><N><T><E><W><P><K><W><E><Q><I><M><A><P><D><P><V><D><P><E><L><L><A><D><Q><A><R><N><A><P... | Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s... | B8H8V7 |
P31314 | TLX1_HUMAN | T-cell leukemia/lymphoma protein 3 | Homo | <M><E><H><L><G><P><H><H><L><H><P><G><H><A><E><P><I><S><F><G><I><D><Q><I><L><N><S><P><D><Q><G><G><C><M><G><P><A><S><R><L><Q><D><G><E><Y><G><L><G><C><L><V><G><G><A><Y><T><Y><G><G><G><G><S><A><A><A><T><G><A><G><G><A><G><A><Y><G><T><G><G><P><G><G><P><G><G><P><A><G><G><G><G><A><C><S><M><G><P><L><T><G><S><Y><N><V><N><M><A><L... | Controls the genesis of the spleen. Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.<BOP> | P31314 |
A3MHE3 | KYNB_BURM7 | N-formylkynurenine formamidase | pseudomallei group | <M><D><T><I><W><D><I><S><P><P><I><A><P><A><T><P><V><W><P><G><D><T><P><V><G><I><E><R><V><W><R><I><E><A><G><S><P><V><N><V><A><R><V><T><L><S><P><H><T><G><A><H><A><D><A><P><L><H><Y><D><A><D><G><T><P><I><G><A><V><P><L><D><A><Y><L><G><R><C><R><V><I><H><C><I><G><A><R><S><A><V><T><P><E><H><V><R><A><A><L><A><G><A><P><P><R><V><L... | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.<BOP> | A3MHE3 |
C5BS84 | NUSB_TERTT | Antitermination factor NusB | Teredinibacter | <M><K><V><T><A><A><T><R><S><R><A><R><H><F><A><M><Q><A><I><Y><Q><W><Q><M><N><G><N><P><L><H><V><I><E><A><E><F><H><T><D><N><D><M><S><K><V><D><T><E><Y><F><H><E><L><F><H><G><V><A><A><D><K><S><A><L><D><A><C><F><L><P><H><L><K><S><L><P><L><E><K><L><D><P><V><T><L><A><L><L><R><Q><A><T><F><E><L><K><N><R><V><D><V><P><Y><K><V><V><I... | Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.<BOP> | C5BS84 |
P0A4Y9 | ARGR_MYCBO | Arginine repressor | Mycobacterium tuberculosis complex | <M><S><R><A><K><A><A><P><V><A><G><P><E><V><A><A><N><R><A><G><R><Q><A><R><I><V><A><I><L><S><S><A><Q><V><R><S><Q><N><E><L><A><A><L><L><A><A><E><G><I><E><V><T><Q><A><T><L><S><R><D><L><E><E><L><G><A><V><K><L><R><G><A><D><G><G><T><G><I><Y><V><V><P><E><D><G><S><P><V><R><G><V><S><G><G><T><D><R><M><A><R><L><L><G><E><L><L><V><S... | Regulates arginine biosynthesis genes.<BOP> | P0A4Y9 |
P45561 | AMEL_PIG | Leucine-rich amelogenin peptide | Sus | <M><G><T><W><I><L><F><A><C><L><L><G><A><A><F><S><M><P><L><P><P><H><P><G><H><P><G><Y><I><N><F><S><Y><E><V><L><T><P><L><K><W><Y><Q><N><M><I><R><H><P><Y><T><S><Y><G><Y><E><P><M><G><G><W><L><H><H><Q><I><I><P><V><V><S><Q><Q><T><P><Q><S><H><A><L><Q><P><H><H><H><I><P><M><V><P><A><Q><Q><P><G><I><P><Q><Q><P><M><M><P><L><P><G><Q... | Plays a role in the biomineralization of teeth. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.<BOP> | P45561 |
Q97DK4 | GUAC_CLOAB | Guanosine 5'-monophosphate oxidoreductase | Clostridium | <M><E><S><V><F><D><Y><E><D><I><Q><L><I><P><A><K><C><I><V><R><S><R><S><E><C><D><T><S><V><I><L><G><E><H><S><F><R><L><P><V><V><P><A><N><M><Q><T><I><I><D><E><N><I><A><L><F><L><A><Q><N><G><Y><F><Y><I><M><H><R><F><E><P><E><K><R><L><S><F><I><K><N><M><K><S><K><G><L><F><A><S><I><S><V><G><V><K><R><E><E><Y><D><F><I><K><Q><L><A><Q... | Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.<BOP> | Q97DK4 |
Q7PC76 | CSLA1_ORYSJ | Glucomannan-synthase 1 | Oryza sativa | <M><E><V><N><G><G><G><A><A><G><L><P><E><A><W><S><Q><V><R><A><P><V><I><V><P><L><L><R><L><A><V><A><V><C><L><T><M><S><V><L><L><F><L><E><R><M><Y><M><A><V><V><I><S><G><V><K><I><L><R><R><R><P><D><R><R><Y><R><C><D><P><I><P><D><D><D><P><E><L><G><T><S><A><F><P><V><V><L><I><Q><I><P><M><F><N><E><R><E><V><Y><Q><L><S><I><G><A><V><C... | Possesses glucomannan synthase and mannan synthase activities in vitro. Mannan synthase consists of a 4-beta-mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4-mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase. Galactomannan is a noncellulosic polysacc... | Q7PC76 |
A1SSZ3 | DCD_PSYIN | Deoxycytidine triphosphate deaminase | Psychromonas | <M><R><L><C><D><T><H><I><E><E><Y><L><D><A><G><K><I><V><I><T><P><R><P><P><K><S><A><I><S><G><V><S><V><D><I><R><L><G><N><E><F><R><V><F><S><E><H><T><T><P><Y><I><D><L><S><G><P><K><E><E><V><S><S><A><L><D><K><V><M><S><E><P><I><I><I><A><K><N><E><S><F><F><L><H><P><G><E><L><A><L><A><V><T><Y><E><N><V><T><L><P><D><D><I><V><G><W><L... | Catalyzes the deamination of dCTP to dUTP.<BOP> | A1SSZ3 |
Q4JB41 | RL4_SULAC | 50S ribosomal protein L4 | Sulfolobus | <M><Y><I><E><L><Q><T><K><K><V><S><V><L><D><L><K><G><N><Q><L><E><E><I><E><L><P><L><F><F><S><Y><P><V><R><K><D><L><I><R><R><V><F><L><S><E><F><T><K><S><L><Q><P><K><G><R><D><P><L><A><G><K><R><T><S><A><L><S><F><G><I><N><L><G><I><A><R><V><P><R><V><K><G><S><G><E><A><A><L><A><P><N><T><V><G><G><R><L><A><F><P><P><T><T><E><K><R><L... | Forms part of the polypeptide exit tunnel.<BOP> | Q4JB41 |
A1CM86 | MMM1_ASPCL | Maintenance of mitochondrial morphology protein 1 | Aspergillus subgen. Fumigati | <M><S><S><Q><P><G><D><P><A><T><L><P><A><Q><S><S><L><S><F><T><Q><G><F><L><L><G><Q><L><S><V><V><L><V><L><A><A><F><I><K><F><F><I><F><G><E><A><P><P><P><P><S><R><G><L><S><H><R><S><A><T><H><R><R><S><N><S><I><Y><S><N><S><P><Q><E><A><G><S><R><S><L><R><E><K><P><S><T><S><N><V><L><R><P><V><P><S><S><S><T><N><T><R><S><I><L><R><K><T... | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm... | A1CM86 |
Q97PP4 | GLMM_STRPN | Phosphoglucosamine mutase | Streptococcus | <M><G><K><Y><F><G><T><D><G><V><R><G><E><A><N><L><E><L><T><P><E><L><A><F><K><L><G><R><F><G><G><Y><V><L><S><Q><H><E><T><E><A><P><K><V><F><V><G><R><D><T><R><I><S><G><E><M><L><E><S><A><L><V><A><G><L><L><S><V><G><I><H><V><Y><K><L><G><V><L><A><T><P><A><V><A><Y><L><V><E><T><E><G><A><S><A><G><V><M><I><S><A><S><H><N><P><A><L><D... | Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP> | Q97PP4 |
Q9NTI7 | INKA2_HUMAN | Inka box actin regulator 2 | Homo | <M><T><M><E><S><R><E><M><D><C><Y><L><R><R><L><K><Q><E><L><M><S><M><K><E><V><G><D><G><L><Q><D><Q><M><N><C><M><M><G><A><L><Q><E><L><K><L><L><Q><V><Q><T><A><L><E><Q><L><E><I><S><G><G><G><P><V><P><G><S><P><E><G><P><R><T><Q><C><E><H><P><C><W><E><G><G><R><G><P><A><R><P><T><V><C><S><P><S><S><Q><P><S><L><G><S><S><T><K><F><P><S... | Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.<BOP> | Q9NTI7 |
A8EYV5 | FOLD_RICCK | Methenyltetrahydrofolate cyclohydrolase | belli group | <M><N><N><I><I><D><G><K><A><L><A><N><E><I><L><A><D><L><K><L><E><I><Q><E><L><K><D><K><T><N><T><S><P><K><L><A><I><V><L><V><G><N><N><P><A><S><I><I><Y><V><K><H><K><I><K><N><A><H><N><I><G><I><D><T><L><L><V><N><L><S><T><N><I><H><T><D><D><L><I><L><K><I><N><E><L><N><L><N><N><E><I><S><G><I><I><V><Q><L><P><L><P><R><S><I><D><T><N... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | A8EYV5 |
B0R4J3 | CHEF1_HALS3 | Taxis protein CheF1 | Halobacterium | <M><S><E><S><E><Y><K><I><A><D><G><S><G><K><F><L><Q><A><V><K><D><G><R><R><M><K><D><A><Q><W><S><K><G><R><I><L><L><S><N><K><R><I><V><L><A><G><S><E><G><K><R><N><L><P><L><S><E><V><Q><G><L><S><G><R><H><D><V><N><Q><T><V><A><K><V><G><N><Y><V><S><I><R><M><T><N><E><S><V><M><L><V><S><L><G><D><N><T><E><T><F><E><S><K><L><Y><G><A><L... | Involved in taxis signal transduction. Essential for the ability to control the direction of flagellar rotation. May have a role between CheY and the flagellum.<BOP> | B0R4J3 |
B8IPW1 | TRPA_METNO | Tryptophan synthase alpha chain | Methylobacterium | <M><T><T><R><L><D><D><T><F><A><R><C><R><A><E><G><R><A><A><L><V><T><Y><V><M><A><G><D><P><D><P><E><T><S><F><A><V><L><R><A><L><P><A><A><G><A><D><I><V><E><F><G><L><P><F><T><D><P><M><A><D><G><P><A><I><Q><A><A><G><L><R><A><L><K><A><G><Q><S><V><A><R><T><L><D><L><V><R><R><F><R><A><E><D><P><R><T><P><V><I><L><M><G><Y><Y><N><P><I... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B8IPW1 |
A2ZMH2 | NEK2_ORYSI | NimA-related protein kinase 2 | Oryza sativa | <M><D><Q><Y><E><V><L><E><Q><I><G><K><G><A><F><G><S><A><L><L><V><R><H><K><L><E><K><K><K><Y><V><L><K><K><I><R><L><A><R><Q><T><D><R><T><R><R><S><A><H><Q><E><M><Q><L><I><A><T><V><R><N><P><F><I><V><E><Y><K><D><S><W><V><E><K><G><C><Y><V><C><I><V><I><G><Y><C><E><G><G><D><M><A><E><A><I><K><R><A><N><G><T><Y><F><S><E><E><K><L><C... | May be involved in plant development processes.<BOP> | A2ZMH2 |
P74891 | SSAS_SALTY | Secretion system apparatus protein SsaS | Salmonella | <M><N><D><S><E><L><T><Q><F><V><T><Q><L><L><W><I><V><L><F><T><S><M><P><V><V><L><V><A><S><V><V><G><V><I><V><S><L><V><Q><A><L><T><Q><I><Q><D><Q><T><L><Q><F><M><I><K><L><L><A><I><A><I><T><L><M><V><S><Y><P><W><L><S><G><I><L><L><N><Y><T><R><Q><I><M><L><R><I><G><E><H><G> | Part of a type III secretion system.<BOP> | P74891 |
P60482 | ISPT_GEOSL | Isoprenyl transferase | Geobacter | <M><H><G><L><I><P><D><K><L><P><R><H><L><A><I><I><M><D><G><N><G><R><W><A><Q><E><R><M><L><T><R><I><I><G><H><Q><K><G><V><E><T><V><R><I><I><V><E><E><C><S><R><L><G><I><G><Y><L><T><L><F><A><F><S><A><E><N><W><L><R><P><K><T><E><V><K><A><L><M><A><L><L><K><K><Y><I><A><S><E><A><A><R><M><D><A><N><N><I><R><F><N><V><I><G><N><R><D><E... | Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.<BOP> | P60482 |
O42503 | HXC8A_TAKRU | FrHOXC-8 | Takifugu | <M><S><S><Y><F><V><N><P><L><F><S><K><Y><K><G><G><E><S><L><E><P><T><Y><Y><D><C><R><F><P><Q><S><V><A><R><S><H><T><L><V><Y><G><P><G><G><A><A><P><G><F><Q><H><P><S><H><H><V><Q><D><F><F><H><H><G><T><T><G><I><S><N><P><G><Y><Q><Q><N><P><C><A><L><A><C><H><G><D><A><T><K><F><Y><G><Y><E><A><L><P><R><Q><T><L><Y><G><T><Q><Q><D><A><S... | Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP> | O42503 |
P0C7J2 | XANA_XANCP | Phosphomannomutase | Xanthomonas | <M><T><L><P><A><F><K><A><Y><D><I><R><G><R><V><P><D><E><L><N><E><D><L><A><R><R><I><G><V><A><L><A><A><Q><L><D><Q><G><P><V><V><L><G><H><D><V><R><L><A><S><P><A><L><Q><E><A><L><S><A><G><L><R><A><S><G><R><E><V><I><D><I><G><L><C><G><T><E><E><V><Y><F><Q><T><D><H><L><K><A><A><G><G><V><M><V><T><A><S><H><N><P><M><D><Y><N><G><M><K... | Involved in xanthan production.<BOP> | P0C7J2 |
Q6CZP5 | PCKA_PECAS | Phosphoenolpyruvate carboxykinase (ATP) | Pectobacterium | <M><Q><I><N><G><I><T><P><Q><A><L><A><A><Y><G><I><H><D><V><R><D><I><V><Y><N><P><S><Y><E><L><L><F><K><E><E><R><S><P><T><L><Q><G><Y><E><R><G><I><E><T><Q><L><G><A><V><A><V><D><T><G><I><F><T><G><R><S><P><K><D><K><Y><I><V><R><D><D><V><T><R><D><T><V><W><W><S><D><Q><G><K><G><K><N><D><N><H><P><L><S><Q><E><T><W><T><H><L><K><E><L... | Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.<BOP> | Q6CZP5 |
Q5LQJ5 | FABH_RUEPO | 3-oxoacyl-[acyl-carrier-protein] synthase III | Ruegeria | <M><A><G><R><A><V><V><K><G><V><G><H><Y><L><P><E><R><V><V><P><N><A><A><F><E><K><T><L><D><T><T><D><E><W><I><R><S><R><S><G><I><E><R><R><H><F><A><A><E><G><E><T><T><S><D><L><A><T><R><A><A><E><A><A><L><A><D><A><G><I><S><A><E><Q><I><D><A><I><V><L><A><T><S><T><A><D><L><T><F><P><S><A><A><T><M><V><Q><A><R><L><G><M><T><N><G><Y><A... | Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A... | Q5LQJ5 |
A1WQ68 | RUVB_VEREI | Holliday junction ATP-dependent DNA helicase RuvB | Verminephrobacter | <M><T><L><Q><T><D><D><F><A><P><A><P><A><R><R><V><V><S><A><A><P><A><S><P><Q><E><Q><A><I><E><R><A><L><R><P><K><L><L><Q><E><Y><V><G><Q><V><K><A><R><E><Q><L><E><I><F><I><G><A><A><R><Q><R><G><E><A><L><D><H><V><L><L><F><G><P><P><G><L><G><K><T><T><L><S><H><I><I><A><A><E><L><G><V><N><L><R><Q><T><S><G><P><V><L><E><K><P><K><D><L... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP> | A1WQ68 |
P83741 | WNK1_MOUSE | Protein kinase with no lysine 1 | Mus | <M><S><D><G><A><A><E><K><Q><S><G><T><P><G><F><L><T><P><P><A><P><V><P><K><N><G><S><S><S><D><S><S><V><G><E><K><L><G><A><T><V><A><D><S><G><V><G><R><T><E><E><Y><R><R><R><R><H><T><M><D><K><D><S><R><G><A><A><A><T><T><T><P><T><E><H><R><F><F><R><R><S><V><I><C><D><S><N><A><T><A><L><E><L><P><G><L><P><L><S><I><P><Q><P><S><V><P><A... | Dominant-negative regulator of the longer isoform 1. Does not have kinase activity, does not directly inhibit WNK4 and has no direct effect on sodium and chloride ion transport. Down-regulates sodium-chloride cotransporter activity indirectly by inhibiting isoform 1, it associates with isoform 1 and attenuates its kina... | P83741 |
O83237 | RL15_TREPA | 50S ribosomal protein L15 | Treponema | <M><A><D><F><H><L><I><A><P><K><G><A><N><R><A><R><R><I><V><G><R><G><S><S><S><G><R><G><T><T><S><G><R><G><T><K><G><Q><Q><A><R><A><G><H><K><A><Y><V><G><F><E><G><G><Q><M><P><L><Y><R><R><V><P><R><R><G><F><S><N><C><A><F><K><K><E><Y><A><V><V><N><V><G><A><L><E><F><V><Y><A><P><G><E><T><V><N><R><Q><T><L><I><E><K><G><L><V><K><G><R... | Binds to the 23S rRNA.<BOP> | O83237 |
A7ZR20 | ZAPA_ECO24 | Z ring-associated protein ZapA | Escherichia | <M><S><A><Q><P><V><D><I><Q><I><F><G><R><S><L><R><V><N><C><P><P><D><Q><R><D><A><L><N><Q><A><A><D><D><L><N><Q><R><L><Q><D><L><K><E><R><T><R><V><T><N><T><E><Q><L><V><F><I><A><A><L><N><I><S><Y><E><L><A><Q><E><K><A><K><T><R><D><Y><A><A><S><M><E><Q><R><I><R><M><L><Q><Q><T><I><E><Q><A><L><L><E><Q><G><R><I><T><E><K><T><N><Q><N... | Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.<BOP> | A7ZR20 |
Q9C0D4 | Z518B_HUMAN | Zinc finger protein 518B | Homo | <M><K><D><I><G><Q><Q><L><Y><T><T><H><L><N><G><G><H><N><S><L><T><M><S><P><K><Q><P><D><A><N><G><A><P><R><P><N><R><Q><E><A><Q><T><L><L><Y><Q><G><S><E><A><E><A><A><M><M><T><I><A><T><C><A><K><C><K><S><V><H><K><I><S><L><Q><D><L><Q><K><G><T><G><K><D><G><M><Y><V><C><F><Q><C><S><L><G><A><A><P><P><N><F><H><F><V><S><N><N><S><S><A... | Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes.<BOP> | Q9C0D4 |
B4U4X0 | UPPP_STREM | Undecaprenyl pyrophosphate phosphatase | Streptococcus | <M><L><F><I><E><L><L><K><A><I><F><F><G><V><I><E><G><V><T><E><W><L><P><I><S><S><T><G><H><L><I><L><V><Q><E><F><I><R><L><H><Q><D><K><A><F><M><E><M><F><N><I><V><I><Q><L><G><A><I><I><A><V><I><V><I><Y><F><E><R><L><N><P><F><Q><P><G><K><S><P><Q><Q><I><R><L><T><W><Q><L><W><L><K><V><A><I><A><C><I><P><S><I><I><I><A><V><P><L><D><D... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | B4U4X0 |
A9BPS2 | RS19_DELAS | 30S ribosomal protein S19 | Delftia | <M><T><R><S><L><K><K><G><P><F><V><D><H><H><L><L><A><K><A><E><K><A><V><A><T><K><D><K><K><P><V><K><T><W><S><R><R><S><M><V><L><P><E><F><I><G><L><T><I><A><V><H><N><G><K><Q><H><V><P><V><Y><V><T><D><Q><M><V><G><H><K><L><G><E><F><A><L><T><R><T><F><K><G><H><P><A><D><K><K><A><K><K> | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | A9BPS2 |
Q8X7Y6 | TRUD_ECO57 | tRNA-uridine isomerase D | Escherichia | <M><I><E><F><D><N><L><T><Y><L><H><G><K><P><Q><G><T><G><L><L><K><A><N><P><E><D><F><V><V><V><E><D><L><G><F><E><P><D><G><E><G><E><H><I><L><V><R><I><L><K><N><G><C><N><T><R><F><V><A><D><A><L><A><K><F><L><K><I><H><A><R><E><V><S><F><A><G><Q><K><D><K><H><A><V><T><E><Q><W><L><C><A><R><V><P><G><K><E><M><P><D><L><S><A><F><Q><L><E... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | Q8X7Y6 |
Q6CNA0 | YPI1_KLULA | Type 1 phosphatases regulator YPI1 | Kluyveromyces | <M><S><E><G><P><S><A><L><P><E><G><T><H><T><V><T><V><T><E><V><P><Q><L><L><Q><L><R><A><G><Q><N><E><K><N><K><T><K><K><K><D><T><K><S><K><V><R><W><D><E><K><V><I><D><N><E><N><M><N><K><K><K><T><K><I><C><C><I><F><H><P><N><T><P><L><E><S><D><E><E><E><E><G><E><C><E><H><D><H><N><H><G><H><D><S><S><S><S><S><S><S><S><S><S><D><E><D><E... | Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.<BOP> | Q6CNA0 |
Q7Y8G0 | NU4LM_HEMAU | NADH dehydrogenase subunit 4L | Hemiechinus | <M><S><I><V><Y><M><N><V><M><L><A><F><M><I><A><L><I><G><T><L><L><Y><R><H><H><L><M><S><S><L><M><C><L><E><G><M><M><L><A><M><Y><I><F><I><S><L><I><S><L><N><M><H><F><T><T><M><Y><M><V><P><L><I><I><L><V><F><A><A><C><E><A><A><L><G><L><A><L><L><V><K><M><F><N><Y><Y><G><N><D><Y><V><Q><N><L><N><L><L><K><C> | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.<BOP> | Q7Y8G0 |
P79357 | TSHB_LAMGL | Thyrotropin beta chain | Lama | <M><T><A><I><F><L><M><S><V><L><F><G><L><A><C><G><Q><A><M><S><F><C><I><P><T><E><Y><M><M><H><V><E><R><K><E><C><A><Y><C><L><T><I><N><T><T><I><C><A><G><Y><C><M><T><R><D><F><N><G><K><L><F><L><P><K><F><A><L><S><Q><D><V><C><T><Y><R><D><F><M><Y><K><T><V><E><I><P><G><C><P><H><H><V><T><P><Y><F><S><Y><P><V><A><V><S><C><K><C><G><K... | Indispensable for the control of thyroid structure and metabolism.<BOP> | P79357 |
P9WIH1 | PE15_MYCTU | PE family immunomodulator PE15 | Mycobacterium tuberculosis complex | <M><T><L><R><V><V><P><E><S><L><A><G><A><S><A><A><I><E><A><V><T><A><R><L><A><A><A><H><A><A><A><A><P><F><I><A><A><V><I><P><P><G><S><D><S><V><S><V><C><N><A><V><E><F><S><V><H><G><S><Q><H><V><A><M><A><A><Q><G><V><E><E><L><G><R><S><G><V><G><V><A><E><S><G><A><S><Y><A><A><R><D><A><L><A><A><A><S><Y><L><S><G><G><L> | May play a pivotal role in the evasion of host immune response by M.tuberculosis. Mediates production of IL-10 via activation of the p38 and ERK1/2 mitogen-activated protein kinase (MAPK) signaling pathways.<BOP> | P9WIH1 |
Q9JX29 | LPXD_NEIMA | UDP-3-O-acylglucosamine N-acyltransferase | Neisseria | <M><I><P><A><T><Y><T><L><S><Q><I><T><A><R><L><G><G><E><W><R><G><E><D><T><S><V><T><A><V><R><P><L><A><D><A><Q><A><E><H><I><S><F><L><A><N><P><K><Y><K><A><E><V><H><D><S><S><A><G><A><V><I><V><S><A><K><A><A><D><G><F><E><G><R><N><L><I><V><A><D><D><P><Y><L><Y><F><A><K><V><A><R><L><F><S><P><V><V><K><A><R><G><G><I><H><P><T><A><V... | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | Q9JX29 |
B4JF25 | WRNXO_DROGR | Werner Syndrome-like exonuclease | Hawaiian Drosophila | <M><D><K><Y><L><I><K><M><P><V><K><L><N><S><I><E><V><T><E><K><K><I><S><A><K><E><E><R><V><K><Q><T><N><A><A><K><K><Q><I><A><T><N><N><N><K><R><K><N><Q><D><T><P><E><M><I><K><D><K><E><N><A><E><S><E><N><P><P><K><R><R><S><S><R><V><T><R><S><M><R><S><M><A><E><D><G><P><A><S><P><E><K><E><I><P><K><K><L><P><F><I><K><Y><S><G><A><I><K... | Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction. Essential for the formation of DNA replication focal centers. Has an important role in maintaining genome stability.<BOP> | B4JF25 |
C3P1F6 | ATPA_BACAA | F-ATPase subunit alpha | Bacillus cereus group | <M><S><I><R><A><E><E><I><S><A><L><I><K><Q><Q><I><E><N><Y><Q><S><E><I><E><V><S><D><V><G><T><V><I><Q><V><G><D><G><I><A><R><A><H><G><L><D><N><V><M><A><G><E><L><V><E><F><S><N><G><V><M><G><L><A><Q><N><L><E><E><N><N><V><G><I><I><I><L><G><P><Y><T><E><I><R><E><G><D><E><V><R><R><T><G><R><I><M><Q><V><P><V><G><K><E><L><I><G><R><V... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP> | C3P1F6 |
Q0TKW0 | BETB_ECOL5 | Betaine aldehyde dehydrogenase | Escherichia | <M><S><R><M><A><E><Q><Q><L><Y><I><H><G><G><Y><T><S><A><T><S><G><H><T><F><E><T><I><N><P><A><N><G><N><V><L><A><T><V><Q><A><A><G><R><E><D><V><D><R><A><V><K><S><A><Q><Q><G><Q><K><I><W><A><A><M><T><A><M><E><R><S><R><I><L><R><R><A><V><D><I><L><R><E><R><N><D><E><L><A><K><L><E><T><L><D><T><G><K><A><Y><S><E><T><S><T><V><D><I><V... | Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.<BOP> | Q0TKW0 |
Q64143 | P55G_MOUSE | p55PIK | Mus | <M><Y><N><T><V><W><S><M><D><R><D><D><A><D><W><R><E><V><M><M><P><Y><S><T><E><L><I><F><Y><I><E><M><D><P><P><A><L><P><P><K><P><P><K><P><M><T><P><A><V><T><N><G><M><K><D><S><F><I><S><L><Q><D><A><E><W><Y><W><G><D><I><S><R><E><E><V><N><D><K><L><R><D><M><P><D><G><T><F><L><V><R><D><A><S><T><K><M><Q><G><D><Y><T><L><T><L><R><K><G... | Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.<BOP> | Q64143 |
Q1QVQ3 | GLPK_CHRSD | Glycerokinase | Chromohalobacter | <M><H><S><Y><L><L><S><I><D><Q><G><T><T><S><S><R><A><I><L><F><D><R><Q><G><R><V><A><G><V><A><Q><E><E><F><A><Q><H><F><P><A><S><G><W><V><E><H><D><A><E><D><I><W><Q><S><V><L><R><T><C><R><Q><V><M><E><S><T><G><A><S><I><E><E><I><A><G><I><G><M><T><N><Q><R><E><T><T><L><L><W><D><R><R><T><G><E><P><L><H><R><A><I><V><W><Q><D><R><R><T... | Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP> | Q1QVQ3 |
Q26997 | HGXR_TOXGO | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | Toxoplasma | <M><A><S><K><P><I><E><D><Y><G><K><G><K><G><R><I><E><P><M><Y><I><P><D><N><T><F><Y><N><A><D><D><F><L><V><P><P><H><C><K><P><Y><I><D><K><I><L><L><P><G><G><L><V><K><D><R><V><E><K><L><A><Y><D><I><H><R><T><Y><F><G><E><E><L><H><I><I><C><I><L><K><G><S><R><G><F><F><N><L><L><I><D><Y><L><A><T><I><Q><K><Y><S><G><R><E><S><S><V><P><P... | Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine, leading to IMP, GMP and XMP, respectively. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.<BOP> | Q26997 |
P68753 | MATK_PAECA | Intron maturase | Paeonia | <M><E><K><S><Q><G><Y><L><E><L><D><K><S><W><R><H><N><F><L><Y><P><L><I><F><Q><E><Y><I><Y><A><L><A><H><E><Q><G><L><N><R><S><I><L><L><E><N><T><D><H><D><N><K><Y><S><S><L><I><V><K><R><L><I><T><L><I><H><Q><Q><N><H><F><L><I><F><D><N><D><S><N><Q><N><P><F><W><K><H><N><N><N><L><Y><S><Q><T><I><S><E><G><F><V><I><I><V><E><I><P><F><S... | Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP> | P68753 |
F9X9V3 | FER7_ZYMTI | Ferrichrome A-like siderophore biosynthesis protein MYCGRDRAFT_70577 | Zymoseptoria | <M><R><T><S><S><E><S><H><S><R><S><D><A><F><N><G><K><N><D><A><S><Q><V><T><V><D><S><D><S><A><S><K><D><H><H><D><H><D><H><H><H><K><D><T><S><I><N><E><R><Q><S><Q><H><V><H><Q><Q><A><G><V><S><K><V><E><A><F><N><K><A><L><Y><Q><S><G><P><S><G><R><L><L><L><Y><V><L><V><A><S><L><A><L><T><M><F><A><Y><A><L><D><Q><G><I><T><Y><Q><F><N><A... | Siderophore transporter; part of the gene cluster 14 that mediates the biosynthesis of a ferrichrome A-like siderophors which may contribute to organismal virulence.<BOP> | F9X9V3 |
C3P663 | LSPA_BACAA | Signal peptidase II | Bacillus cereus group | <M><I><Y><Y><V><I><A><L><F><V><I><A><I><D><Q><I><S><K><W><L><I><V><K><N><M><E><L><G><T><S><I><P><I><I><D><N><V><L><Y><I><T><S><H><R><N><R><G><A><A><W><G><I><L><E><N><K><M><W><F><F><Y><I><I><T><V><V><F><V><V><F><I><V><F><Y><M><K><K><Y><A><K><T><D><K><L><L><G><I><S><L><G><L><I><L><G><G><A><I><G><N><F><I><D><R><V><F><R><Q... | This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP> | C3P663 |
A2RCA2 | PURA_STRPG | IMP--aspartate ligase | Streptococcus | <M><T><S><V><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><T><D><F><L><S><A><D><A><E><V><I><A><R><Y><Q><G><G><D><N><A><G><H><T><I><V><I><D><G><K><K><F><K><L><H><L><I><P><S><G><I><F><F><P><Q><K><I><S><V><I><G><N><G><V><V><V><N><P><K><S><L><V><K><E><L><A><Y><L><H><D><E><G><V><T><T><D><N><L><R><I><S><D><R><A><H><V><I><L><P... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | A2RCA2 |
P30565 | MT_THEVL | Metallothionein | Thermostichus | <M><T><T><V><T><Q><M><K><C><A><C><P><H><C><L><C><I><V><S><L><N><D><A><I><M><V><D><G><K><P><Y><C><S><E><V><C><A><N><G><T><C><K><E><N><S><G><C><G><H><A><G><C><G><C><G><S><A> | This protein complexes cadmium, zinc and copper.<BOP> | P30565 |
Q3SGU9 | RISB_THIDA | 6,7-dimethyl-8-ribityllumazine synthase | Thiobacillus | <M><G><T><S><S><D><I><F><E><L><D><P><I><Y><Q><G><K><G><L><R><I><G><I><V><M><S><R><F><N><K><D><I><C><E><G><L><L><S><A><C><E><T><E><L><D><R><L><G><V><A><R><E><D><V><L><L><V><D><V><P><G><A><L><E><H><P><L><A><L><Q><K><M><A><Q><S><A><R><Y><D><A><L><I><A><I><G><A><V><V><R><G><D><T><Y><H><F><E><I><V><S><N><E><S><S><R><G><I><L... | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP> | Q3SGU9 |
A0KKN1 | RBSD_AERHH | D-ribose pyranase | Aeromonas | <M><K><R><G><V><L><L><N><A><P><L><S><A><L><V><A><R><M><G><H><T><D><E><I><T><V><C><D><A><G><L><P><I><P><A><G><P><E><R><I><D><L><A><L><M><A><G><T><P><S><L><E><T><V><L><T><A><L><L><T><D><L><V><V><E><K><V><I><M><A><S><E><I><K><Q><I><S><P><A><A><H><Q><A><L><V><D><Q><L><E><A><H><A><A><A><Q><G><K><P><I><T><I><E><Y><C><L><H><E... | Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.<BOP> | A0KKN1 |
Q9XZK2 | O16O3_CONST | Omega-conotoxin SO-3 | Pionoconus | <M><K><L><T><C><M><V><I><V><A><V><L><L><L><T><A><C><Q><L><I><T><A><D><D><S><R><G><T><Q><K><H><R><T><L><R><S><K><T><K><L><S><M><S><T><R><C><K><A><A><G><K><P><C><S><R><I><A><Y><N><C><C><T><G><S><C><R><S><G><K><C><G> | Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This peptide selectively targets Cav2.2/CACNA1B (IC(50)=160 nM) voltage-gated calcium channels . When tested in mammals, this toxin displays an analgesic potency similar to MVIIA in a range of acute and chronic pain... | Q9XZK2 |
Q889W8 | RL2_PSESM | 50S ribosomal protein L2 | Pseudomonas | <M><A><I><V><K><C><K><P><T><S><P><G><R><R><F><V><V><K><V><V><N><Q><E><L><H><K><G><A><P><H><A><P><L><L><E><K><K><S><K><T><G><G><R><N><N><N><G><R><I><T><T><R><H><I><G><G><G><H><K><Q><H><Y><R><L><V><D><F><R><R><N><D><K><D><G><I><T><A><T><V><E><R><I><E><Y><D><P><N><R><T><A><H><I><A><L><L><L><Y><A><D><G><E><R><R><Y><I><I><A... | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<... | Q889W8 |
Q6TNU3 | INT10_DANRE | Integrator complex subunit 10 | Danio | <M><S><A><Q><G><D><C><E><F><L><V><K><R><A><R><E><L><V><P><Q><D><P><Y><A><A><K><A><W><L><I><T><A><R><T><L><Y><P><T><D><F><N><I><Q><Y><E><M><Y><S><I><E><R><N><A><E><R><T><S><S><A><G><R><L><L><Y><D><I><F><V><N><F><P><D><Q><P><V><V><W><R><E><I><S><A><I><T><A><A><L><R><N><D><S><Q><D><K><H><A><Q><F><L><K><G><V><F><E><T><L><P... | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.<BOP> | Q6TNU3 |
A0R502 | IPDE2_MYCS2 | 5OH-HIP-CoA dehydrogenase beta subunit | Mycolicibacterium | <M><S><E><E><R><E><L><L><R><E><T><V><A><A><L><V><E><K><H><A><S><P><E><A><V><R><A><A><M><E><S><E><L><G><Y><D><P><N><L><W><R><L><L><C><E><Q><V><G><A><A><A><L><V><I><P><E><E><F><G><G><A><G><G><E><L><A><D><A><A><V><V><L><E><E><L><G><K><A><L><V><P><T><P><L><L><G><T><T><L><A><E><I><A><L><L><S><V><G><R><T><E><P><L><E><E><L><A... | Involved in cholesterol degradation. Catalyzes the dehydrogenation of 5OH-HIP-CoA to 5OH-HIPE-CoA.<BOP> | A0R502 |
C4KIK6 | THII_SULIK | tRNA 4-thiouridine synthase | Sulfolobus | <M><L><I><I><I><R><P><S><G><E><I><A><L><K><S><P><R><S><R><R><N><F><E><H><T><L><A><N><N><I><R><S><V><I><K><E><G><K><I><W><R><S><Q><G><V><L><F><L><E><V><N><D><D><N><K><N><I><E><E><L><S><K><V><F><G><I><A><S><F><S><P><V><M><S><I><K><S><Y><N><N><N><L><E><D><I><I><N><K><A><K><E><V><F><A><E><I><V><K><G><K><I><F><S><V><R><A><K... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | C4KIK6 |
A6Q6H8 | RL11_SULNB | 50S ribosomal protein L11 | unclassified Sulfurovum | <M><A><K><K><I><A><E><K><F><K><M><M><I><P><A><G><S><A><N><P><S><P><P><V><G><P><A><L><G><Q><R><G><V><N><I><M><E><F><C><K><A><F><N><E><K><T><K><D><K><M><G><F><K><I><P><V><I><V><T><V><Y><V><D><K><S><F><T><F><E><T><K><Q><P><P><A><S><D><L><I><L><K><A><A><G><I><K><K><G><T><D><N><P><I><L><N><K><V><G><S><I><T><K><A><K><L><D><E... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP> | A6Q6H8 |
B7GGE5 | Y1766_ANOFW | UPF0122 protein Aflv_1766 | Anoxybacillus | <M><L><E><K><T><T><R><M><N><Y><L><Y><D><F><Y><Q><S><L><L><T><P><K><Q><R><N><Y><M><S><L><Y><Y><L><D><D><Y><S><L><G><E><I><A><E><E><Y><E><V><S><R><Q><A><V><Y><D><N><I><K><R><T><E><A><M><L><E><D><Y><E><Q><K><L><L><L><F><Q><K><F><Q><Q><R><H><K><L><L><H><R><L><K><T><H><I><A><E><R><Y><P><N><D><E><E><L><M><K><L><V><L><E><L><E... | Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.<BOP> | B7GGE5 |
A1APF8 | KDSB_PELPD | CMP-2-keto-3-deoxyoctulosonic acid synthase | Pelobacter | <M><N><I><T><A><V><I><P><A><R><F><A><S><V><R><F><P><G><K><A><L><A><I><I><D><G><K><P><M><I><Q><H><V><Y><E><R><T><A><R><A><S><L><V><D><S><V><I><I><A><T><D><D><E><R><I><Q><Q><A><V><S><V><F><G><G><V><C><R><M><T><R><N><D><H><E><T><G><T><D><R><L><A><E><V><A><G><T><L><S><A><D><I><I><V><N><V><Q><G><D><E><P><L><I><A><P><E><M><I... | Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.<BOP> | A1APF8 |
Q4KH68 | NHAA_PSEF5 | Sodium/proton antiporter NhaA | Pseudomonas | <M><P><L><R><S><T><F><T><R><F><F><A><M><E><A><A><S><G><L><L><L><I><A><A><A><I><L><A><L><I><I><N><N><S><P><L><S><W><L><Y><N><G><L><L><E><T><P><V><V><A><Q><V><G><A><L><K><I><A><K><P><L><L><L><W><I><N><D><G><L><M><A><L><F><F><L><L><I><G><L><E><V><K><R><E><V><L><E><G><Q><L><A><K><P><S><Q><I><V><L><P><G><A><A><A><I><G><G><M... | Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.<BOP> | Q4KH68 |
O31819 | YNZD_BACSU | Stage 0 sporulation regulatory protein YnzD | Bacillus | <M><I><R><E><H><L><L><K><E><I><E><K><K><R><A><E><L><L><Q><I><V><M><A><N><G><M><T><S><H><I><T><I><E><L><S><Q><E><L><D><H><L><L><I><Q><Y><Q><K><Q><R><L><R><A><V><A><G><D><E> | Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation.<BOP> | O31819 |
Q9HTX5 | GCST_PSEAE | Glycine cleavage system T protein | Pseudomonas | <M><G><L><R><T><P><L><Y><E><L><H><V><A><L><G><A><K><M><V><D><F><G><G><W><D><M><P><L><H><Y><G><S><Q><V><E><E><H><H><Q><V><R><R><D><C><G><V><F><D><V><S><H><M><T><V><V><D><V><A><G><E><Q><A><T><A><Y><L><Q><H><L><L><A><N><D><V><A><R><L><G><E><T><G><K><A><L><Y><S><A><M><L><N><E><E><G><G><V><V><D><D><L><I><V><Y><L><T><E><H><G... | The glycine cleavage system catalyzes the degradation of glycine.<BOP> | Q9HTX5 |
A3N5K2 | ISPE_BURP6 | 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | pseudomallei group | <M><T><D><T><T><R><S><L><R><D><C><L><A><P><A><K><L><N><L><F><L><H><I><T><G><R><R><P><D><G><Y><H><A><L><Q><S><V><F><Q><L><L><D><W><G><D><R><L><H><F><T><L><R><D><D><G><K><V><S><R><V><T><D><V><P><G><V><P><E><E><S><D><L><V><V><R><A><A><S><L><L><K><A><H><A><G><A><T><L><G><V><D><I><E><I><D><K><R><L><P><M><G><A><G><L><G><G><G... | Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP> | A3N5K2 |
Q325L0 | AROL_SHIBS | Shikimate kinase 2 | Shigella | <M><T><Q><P><L><F><L><I><G><P><R><G><C><G><K><T><T><V><G><M><A><L><A><D><S><L><N><R><R><F><V><D><T><D><Q><W><L><Q><S><Q><L><N><M><T><V><A><E><I><V><E><R><E><E><W><A><G><F><R><A><R><E><T><A><A><L><E><A><V><T><A><P><S><T><V><I><A><T><G><G><G><I><I><L><T><E><F><N><R><H><F><M><Q><N><N><G><I><V><V><Y><L><C><A><P><V><S><V><L... | Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<BOP> | Q325L0 |
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