accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q80VY2 | INKA2_MOUSE | Induced in neural crest by AP2-alpha protein-related homolog | Mus | <M><T><K><E><S><K><D><M><D><C><Y><L><R><R><L><K><Q><E><L><M><S><M><K><E><V><G><D><G><L><Q><D><Q><M><N><C><M><M><G><A><L><Q><E><L><K><L><L><Q><V><Q><T><A><L><E><Q><L><E><I><S><G><G><T><P><T><F><S><C><P><E><S><S><Q><E><Q><P><E><C><P><R><W><Q><G><S><G><G><P><A><G><P><A><A><W><T><S><S><S><Q><P><S><F><D><S><S><P><K><L><P><C... | Inhibitor of the serine/threonine-protein kinase PAK4. Acts by binding PAK4 in a substrate-like manner, inhibiting the protein kinase activity.<BOP> | Q80VY2 |
B5F683 | ZUPT_SALA4 | Zinc transporter ZupT | Salmonella | <M><S><V><P><L><I><L><T><L><L><A><G><A><A><T><F><I><G><A><F><L><G><V><L><G><Q><K><P><S><N><R><V><L><A><F><S><L><G><F><A><A><G><I><M><L><L><I><S><L><M><E><M><L><P><A><A><L><D><T><E><G><M><S><P><V><L><G><Y><G><M><F><I><I><G><L><L><G><Y><F><G><L><D><R><L><L><P><H><A><H><P><Q><D><L><V><Q><K><R><Q><Q><P><L><P><G><S><I><K><R... | Mediates zinc uptake. May also transport other divalent cations.<BOP> | B5F683 |
P12471 | CB21_SOYBN | LHCII type I CAB | Glycine subgen. Soja | <A><S><P><S><T><P><Q><L><G><V><G><R><V><S><M><R><K><T><A><S><K><T><V><S><S><G><S><P><W><Y><G><P><D><R><V><K><Y><L><G><P><F><S><G><E><P><P><S><Y><L><T><G><E><F><P><G><D><Y><G><W><D><T><A><G><L><S><A><D><P><E><T><F><A><K><N><R><E><L><E><V><I><H><S><R><W><A><M><L><G><A><L><G><C><V><F><P><E><L><L><A><R><N><G><V><K><F><G><E... | The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.<BOP> | P12471 |
Q5M140 | RRF_STRT1 | Ribosome-releasing factor | Streptococcus | <M><T><N><T><I><I><E><K><A><K><E><R><F><A><H><T><H><E><S><L><A><R><E><F><G><A><I><R><A><G><R><A><N><A><S><L><L><D><R><I><T><V><E><Y><Y><G><A><P><T><P><L><N><Q><L><A><S><I><T><V><P><E><A><R><V><L><L><I><S><P><F><D><K><G><S><I><A><D><I><E><R><A><I><N><E><S><D><L><G><I><N><P><A><N><D><G><S><V><I><R><L><V><I><P><A><L><T><E... | Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP> | Q5M140 |
Q28691 | PE2R4_RABIT | Prostanoid EP4 receptor | Oryctolagus | <M><S><T><P><V><A><N><A><S><A><S><S><M><P><E><L><L><N><N><P><V><T><I><P><A><V><M><F><I><F><G><V><V><G><N><L><V><A><I><V><V><L><C><K><S><R><K><E><Q><K><E><T><T><F><Y><T><L><V><C><G><L><A><V><T><D><L><L><G><T><L><L><V><S><P><V><T><I><A><T><Y><M><K><G><Q><W><P><G><G><Q><A><L><C><D><Y><S><T><F><I><L><L><F><F><G><L><S><G><L... | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.<BO... | Q28691 |
A4QEZ2 | IF2_CORGB | Translation initiation factor IF-2 | Corynebacterium | <M><P><G><K><L><R><V><H><E><L><A><K><Q><L><G><I><T><S><K><E><L><L><A><T><L><K><D><K><G><E><F><V><K><T><A><S><S><T><I><E><P><P><V><V><K><R><M><Q><E><H><Y><G><S><S><G><S><D><K><S><D><T><A><A><K><P><A><A><A><K><P><A><A><P><K><P><A><A><S><A><A><P><K><P><G><A><P><A><K><P><A><A><P><A><A><K><P><A><P><A><A><A><S><A><A><K><P><G... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP> | A4QEZ2 |
P43828 | SYM_HAEIN | Methionyl-tRNA synthetase | Haemophilus | <M><T><T><Q><P><R><K><I><L><V><T><C><A><L><P><Y><A><N><G><A><I><H><L><G><H><M><L><E><H><I><Q><A><D><I><W><V><R><F><Q><R><M><R><G><N><K><I><H><F><V><C><A><D><D><A><H><G><T><P><I><M><L><N><A><D><K><L><G><I><T><P><E><E><L><I><A><K><A><K><A><D><H><I><R><D><F><A><G><F><N><I><S><F><D><N><Y><H><S><T><H><S><E><E><N><K><Q><L><T... | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.<BOP> | P43828 |
P80998 | GVPA_THIPN | Gas vesicle structural protein | Thiocapsa | <A><K><V><A><N><S><T><D><S><S><S><L><A><E><V><I><D><R><I><L><D><K><G><I><V><I><D><A><W><V><K><V><S><L><V><G><I><E><L><L><A><I><E><A><R><V><V><V><A><S><V><E><T><Y><L><K><Y><A><E><A><I><G><L><T><I><P> | Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms. They allow the positioning of the organism at the favorable depth for growth. GvpA type proteins form the essential core of the structure.<BOP> | P80998 |
A0KRK0 | SELU_SHESA | tRNA 2-selenouridine synthase | Shewanella | <M><T><T><K><L><I><P><A><Q><Q><Y><H><D><I><F><I><A><G><Q><P><L><I><D><L><R><A><P><I><E><F><D><R><G><A><F><P><S><S><V><N><L><P><L><M><V><D><K><E><R><E><K><V><G><T><C><Y><K><A><Q><G><Q><Q><A><A><I><A><L><G><H><S><L><V><H><G><V><V><K><Q><Q><R><I><D><A><W><L><N><F><L><S><A><N><P><E><A><Y><L><Y><C><F><R><G><G><L><R><S><Q><L... | Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS... | A0KRK0 |
Q8RBA4 | NADD_CALS4 | Nicotinate mononucleotide adenylyltransferase | Caldanaerobacter | <M><E><R><E><L><R><L><G><I><M><G><G><T><F><D><P><I><H><Y><G><H><L><V><T><A><E><A><V><R><D><E><F><K><L><D><K><V><I><F><V><P><A><G><N><P><P><H><K><V><K><R><K><V><T><D><K><K><H><R><Y><L><M><T><I><L><A><T><I><T><N><P><F><F><E><V><S><S><I><E><I><D><R><E><G><Y><T><Y><T><I><D><T><I><K><E><F><K><K><M><Y><G><E><K><T><L><F><Y><F... | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP> | Q8RBA4 |
D2RTP8 | RIBL_HALTV | Flavin adenine dinucleotide synthase | Haloterrigena | <M><T><R><T><V><I><A><Q><G><T><F><D><I><L><H><P><G><H><V><H><Y><L><E><E><A><A><A><M><G><D><E><L><L><V><I><V><A><R><K><S><N><V><D><H><K><E><K><P><I><C><P><A><A><Q><R><R><D><V><V><A><A><L><E><A><V><D><D><A><I><V><G><H><E><E><D><I><F><A><P><I><E><A><I><D><P><D><V><I><A><L><G><H><D><Q><H><H><D><D><D><A><I><E><A><E><L><E><R... | Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.<BOP> | D2RTP8 |
P56862 | MET3_ASPTE | Sulfate adenylate transferase | null | <M><A><N><S><P><H><G><G><V><L><K><D><L><L><A><G><D><A><P><R><H><D><E><L><A><A><E><A><E><T><L><P><A><I><V><L><S><E><R><Q><L><C><D><L><E><L><I><M><N><G><G><F><S><P><L><E><G><F><M><T><Q><K><D><F><D><G><V><C><E><N><C><R><L><A><D><G><H><L><F><S><M><P><I><T><L><D><A><S><Q><Q><V><I><S><D><S><N><L><K><P><G><S><R><V><T><L><R><D... | Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.<BOP> | P56862 |
P46381 | KT3K_KLEAK | Probable ketoamine kinase EAE_16955 | Klebsiella | <M><W><Q><A><I><S><N><L><L><S><E><Q><H><T><D><G><A><E><I><E><L><R><N><E><L><P><G><G><E><I><H><A><A><W><H><L><R><F><G><G><K><D><Y><F><V><K><C><D><E><R><E><L><L><P><I><F><T><A><E><A><D><Q><L><E><L><L><S><R><C><K><T><V><S><V><P><Q><V><F><A><V><G><S><D><R><D><Y><S><F><L><V><M><E><Y><L><P><P><R><P><L><D><A><H><N><A><F><L><L... | Ketoamine kinase that phosphorylates ketoamines on the third carbon of the sugar moiety to generate ketoamine 3-phosphate.<BOP> | P46381 |
Q5FHD1 | MIAB_EHRRG | tRNA-i(6)A37 methylthiotransferase | Ehrlichia | <M><Q><G><L><Y><I><K><S><Y><G><C><Q><M><N><V><Y><D><S><L><I><I><E><N><I><I><K><P><L><G><F><S><I><V><N><E><L><S><E><A><D><I><V><I><L><N><T><C><H><I><R><E><K><A><A><E><K><L><Y><S><E><L><G><R><I><R><K><I><Q><E><T><K><N><L><T><I><V><V><A><G><C><V><A><Q><A><E><G><T><E><I><F><T><R><A><P><F><V><D><I><V><V><G><P><Q><S><I><H><T... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | Q5FHD1 |
A9NBT9 | PCKA_COXBR | Phosphoenolpyruvate carboxykinase (ATP) | Coxiella | <M><E><Q><I><A><A><R><V><T><Y><I><N><L><S><P><D><E><L><I><Q><H><A><V><K><N><G><E><G><V><L><S><S><T><G><A><L><A><V><T><T><G><K><R><T><G><R><S><P><K><D><R><F><I><V><K><D><E><Q><T><A><D><Q><V><A><W><G><N><I><N><Q><P><V><E><Q><R><T><F><D><Q><L><W><E><R><A><L><R><Y><L><S><E><R><A><V><Y><I><S><H><L><Q><V><G><A><D><D><N><Y><F... | Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.<BOP> | A9NBT9 |
B3PWU3 | RS13_RHIE6 | 30S ribosomal protein S13 | Rhizobium | <M><A><R><I><A><G><V><N><I><P><T><A><K><R><V><V><I><A><L><T><Y><I><H><G><I><G><P><K><F><A><Q><E><I><V><E><K><V><G><I><P><A><E><R><R><V><H><Q><L><T><D><A><E><V><L><Q><I><R><E><A><I><D><R><D><Y><Q><V><E><G><D><L><R><R><E><T><A><M><N><I><K><R><L><M><D><L><G><C><Y><R><G><L><R><H><R><R><G><L><P><V><R><G><Q><R><T><H><T><N><A... | Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<... | B3PWU3 |
A6LSM2 | RNC_CLOB8 | Ribonuclease III | Clostridium | <M><N><R><Y><T><L><K><E><I><E><E><N><L><G><V><F><F><N><N><H><T><L><L><K><T><A><L><T><H><S><S><F><G><N><Q><F><K><D><A><E><Y><N><E><R><L><E><F><L><G><D><S><V><L><Q><L><C><I><T><E><Y><L><F><N><N><Y><K><H><K><T><E><G><E><L><T><K><I><R><S><L><I><V><C><E><N><S><L><Y><E><I><A><K><K><I><N><L><G><S><Y><I><R><M><S><K><G><E><E><I... | Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.<B... | A6LSM2 |
Q7ZX06 | SPOPA_XENLA | Speckle-type POZ protein A | Xenopus | <M><S><R><V><P><S><P><P><P><P><A><E><M><S><S><G><P><V><A><E><S><W><C><Y><T><Q><I><K><V><V><K><F><S><Y><M><W><T><I><N><N><F><S><F><C><R><E><E><M><G><E><V><I><K><S><S><T><F><S><S><G><A><N><D><K><L><K><W><C><L><R><V><N><P><K><G><L><D><E><E><S><K><D><Y><L><S><L><Y><L><L><L><V><S><C><P><K><S><E><V><R><A><K><F><K><F><S><I><L... | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.<BOP> | Q7ZX06 |
Q5LIY0 | YBEY_BACFN | Endoribonuclease YbeY | Bacteroides | <M><A><I><T><Y><Q><T><E><G><I><K><M><P><D><I><K><K><R><E><T><T><E><W><I><K><A><V><A><A><T><Y><E><K><R><I><G><E><I><A><Y><I><F><C><S><D><E><K><I><L><E><V><N><R><Q><Y><L><Q><H><D><Y><Y><T><D><I><I><T><F><D><Y><C><E><G><N><R><L><S><G><D><L><F><I><S><L><E><T><V><K><T><N><S><E><Q><F><N><T><P><Y><E><E><E><L><H><R><T><I><I><H... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q5LIY0 |
Q65W90 | RS7_MANSM | 30S ribosomal protein S7 | Basfia | <M><P><R><R><R><S><I><E><P><R><K><I><L><P><D><P><K><F><G><S><E><L><L><A><K><F><I><N><V><L><M><V><D><G><K><K><S><I><A><E><S><I><V><Y><N><A><L><D><T><L><A><Q><R><T><N><K><D><A><L><V><A><F><E><E><A><L><E><N><V><R><P><T><V><E><V><K><S><R><R><V><G><G><S><T><Y><Q><V><P><V><E><V><R><P><A><R><R><N><A><L><G><M><R><W><I><V><E><A... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP> | Q65W90 |
A1RWQ5 | RS19_THEPD | 30S ribosomal protein S19 | Thermofilum | <M><E><S><T><S><K><F><T><Y><R><G><Y><T><L><E><E><L><R><Q><M><P><I><E><K><L><A><E><I><M><P><A><R><Q><R><R><S><L><L><R><V><F><K><Q><G><T><S><E><E><H><L><K><L><L><E><K><I><R><R><A><A><K><L><A><S><E><G><K><K><Q><P><V><I><K><T><H><L><R><D><F><I><I><L><P><E><M><V><G><L><T><I><H><V><H><N><G><K><E><F><V><P><V><E><I><T><P><E><K... | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | A1RWQ5 |
Q95LA2 | FMO1_CANLF | Hepatic flavin-containing monooxygenase 1 | Canis | <M><A><K><R><V><A><I><V><G><A><G><V><S><G><L><A><S><I><K><C><C><L><E><E><G><L><E><P><T><C><F><E><R><S><D><D><L><G><G><L><W><R><F><T><E><H><V><E><E><G><R><A><S><L><Y><K><S><V><V><S><N><S><C><K><E><M><S><C><Y><S><D><F><P><F><P><E><D><Y><P><N><Y><V><P><N><S><Q><F><L><E><Y><L><K><M><Y><A><N><R><F><S><L><L><K><C><I><R><F><K... | This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.<BOP> | Q95LA2 |
A9VRT5 | NAMA_BACMK | NADPH dehydrogenase | Bacillus cereus group | <M><E><F><Q><L><F><S><P><Y><T><I><K><D><V><T><L><K><N><R><I><I><M><S><P><M><C><M><Y><S><S><E><N><E><D><G><Q><V><T><N><F><H><L><V><H><Y><G><T><R><A><A><G><Q><V><G><L><V><M><I><E><A><T><A><V><L><P><E><G><R><I><S><N><K><D><L><G><I><W><D><D><N><L><I><E><G><L><H><K><T><T><T><F><I><H><N><N><G><A><K><A><A><I><Q><L><A><H><A><G... | Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.<BOP> | A9VRT5 |
Q7TWT7 | NTPP_MYCBO | Nucleotide pyrophosphatase | Mycobacterium tuberculosis complex | <M><T><R><L><V><L><G><S><A><S><P><G><R><L><K><V><L><R><D><A><G><I><E><P><L><V><I><A><S><H><V><D><E><D><V><V><I><A><A><L><G><P><D><A><V><P><S><D><V><V><C><V><L><A><A><A><K><A><A><Q><V><A><T><T><L><T><G><T><Q><R><I><V><A><A><D><C><V><V><V><A><C><D><S><M><L><Y><I><E><G><R><L><L><G><K><P><A><S><I><D><E><A><R><E><Q><W><R><S... | Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP> | Q7TWT7 |
A9WWT6 | ACSA_BRUSI | Acyl-activating enzyme | Brucella | <M><S><E><K><L><Y><P><V><L><P><E><A><K><K><N><T><L><I><D><N><E><T><Y><L><E><W><Y><E><E><S><M><S><D><P><D><G><F><W><A><K><H><G><R><R><I><D><W><F><K><P><F><T><K><V><K><N><T><D><F><N><G><D><V><T><I><K><W><Y><E><D><G><V><T><N><V><S><Y><N><C><I><D><R><H><L><K><S><R><G><D><K><V><A><I><I><W><E><G><D><N><P><Y><I><D><K><K><I><T... | Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can the... | A9WWT6 |
P0DKW8 | APOE_SAIBB | Apolipoprotein E | Saimiri | <M><K><V><L><W><A><A><F><L><V><A><F><L><A><G><C><Q><G><K><V><E><Q><V><V><E><P><E><L><G><P><E><P><E><L><H><P><Q><A><D><W><Q><S><G><Q><P><W><E><L><A><L><G><R><F><W><D><Y><L><R><W><V><Q><T><L><S><E><Q><V><Q><E><E><L><L><S><S><Q><V><T><Q><E><L><T><A><L><M><D><E><T><M><K><E><L><K><A><Y><K><S><E><L><E><E><Q><L><S><P><V><A><E... | APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amp... | P0DKW8 |
A8M5F5 | ILVD_SALAI | Dihydroxy-acid dehydratase | Salinispora | <M><P><E><L><R><S><R><T><S><T><H><G><R><T><M><A><G><A><R><A><L><W><R><A><T><G><M><T><D><D><D><F><G><K><P><I><V><A><I><A><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><L><G><G><L><V><A><D><A><V><A><E><A><G><G><V><G><R><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><G><G><M><L><Y><S><L><P><S><R><E><L><I><A><D><A><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | A8M5F5 |
P95377 | LPXD_NEIMB | UDP-3-O-acylglucosamine N-acyltransferase | Neisseria | <M><I><P><A><T><Y><T><L><S><Q><I><T><A><R><L><G><G><E><W><R><G><E><D><I><S><V><T><A><V><R><P><L><A><D><A><Q><A><E><H><I><S><F><L><A><N><P><K><Y><K><A><E><V><H><D><S><S><A><G><A><V><I><V><S><A><K><A><A><D><G><F><E><G><R><N><L><I><V><A><D><D><P><Y><L><Y><F><A><K><V><A><R><L><F><S><P><V><V><K><A><R><G><G><I><H><P><T><A><V... | Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | P95377 |
P17271 | H2B_DROHY | Histone H2B | Drosophila | <M><P><P><K><T><S><G><K><A><A><K><K><A><G><K><A><Q><K><N><I><T><K><N><D><K><K><K><K><R><K><R><K><E><S><Y><A><I><Y><I><Y><K><V><L><K><Q><V><H><P><D><T><G><I><S><S><K><A><M><S><I><M><N><S><F><V><N><D><I><F><E><R><I><A><A><E><A><S><R><L><A><H><Y><N><K><R><S><T><I><T><S><R><E><I><Q><T><A><V><R><L><L><L><P><G><E><L><A><K><H... | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v... | P17271 |
B8DU56 | ARGB_BIFA0 | NAG kinase | Bifidobacterium | <M><H><T><D><L><G><P><D><Q><K><A><E><V><L><I><E><A><L><P><W><L><E><E><F><F><G><K><T><I><V><I><K><Y><G><G><N><A><M><V><N><D><H><L><K><E><C><F><A><E><D><M><V><F><L><R><Q><V><G><I><H><P><V><V><V><H><G><G><G><P><Q><I><S><Q><M><L><K><A><L><G><I><H><S><E><F><K><G><G><L><R><V><T><T><P><E><A><M><D><V><V><R><M><V><L><T><G><K><V... | Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP> | B8DU56 |
Q8N127 | O5AS1_HUMAN | Olfactory receptor OR11-168 | Homo | <M><L><E><S><N><Y><T><M><P><T><E><F><L><F><V><G><F><T><D><Y><L><P><L><R><V><T><L><F><L><V><F><L><L><V><Y><T><L><T><M><V><G><N><I><L><L><I><I><L><V><N><I><N><S><S><L><Q><I><P><M><Y><Y><F><L><S><N><L><S><F><L><D><I><S><C><S><T><A><I><T><P><K><M><L><A><N><F><L><A><S><R><K><S><I><S><P><Y><G><C><A><L><Q><M><F><F><F><A><S><F... | Odorant receptor.<BOP> | Q8N127 |
Q086G7 | PNP_SHEFN | Polynucleotide phosphorylase | Shewanella | <M><N><P><I><V><K><S><F><E><Y><G><Q><H><T><V><T><L><E><T><G><V><I><A><R><Q><A><D><A><A><V><L><A><S><M><G><D><T><T><V><L><V><T><V><V><G><K><K><V><A><D><L><S><R><D><F><F><P><L><T><V><N><Y><Q><E><K><T><Y><A><A><G><K><I><P><G><G><F><F><K><R><E><G><R><P><S><E><D><E><T><L><I><A><R><L><I><D><R><P><I><R><P><L><F><P><N><G><F><K... | Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP> | Q086G7 |
Q8CB27 | OTU1_MOUSE | Ubiquitin thioesterase OTU1 | Mus | <M><F><G><G><A><K><G><G><H><F><G><V><P><P><A><G><Y><S><G><A><V><P><Q><S><E><A><G><T><K><A><G><P><A><G><G><R><P><A><D><T><M><W><R><V><R><C><K><A><K><G><G><T><H><L><L><Q><G><L><S><S><R><T><R><L><R><E><L><Q><G><Q><I><A><A><I><T><G><I><A><P><G><S><Q><R><I><L><V><G><Y><P><P><E><C><L><D><L><S><D><R><D><I><T><L><G><D><L><P><I... | Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates... | Q8CB27 |
A0LPG2 | PROA_SYNFM | Glutamyl-gamma-semialdehyde dehydrogenase | Syntrophobacter | <M><R><E><E><V><L><T><M><G><K><R><A><R><Q><A><A><H><H><M><A><K><V><G><D><V><H><K><R><K><A><L><E><H><M><A><L><N><I><E><G><A><E><A><A><I><R><E><A><N><D><K><D><I><R><A><A><V><A><K><G><L><P><A><A><K><V><D><R><L><R><L><D><A><K><V><L><E><E><M><A><C><G><L><K><E><V><A><R><L><S><D><P><V><G><E><I><T><R><M><W><T><R><P><N><G><L><R... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP> | A0LPG2 |
Q57184 | TTCA_HAEIN | tRNA 2-thiocytidine biosynthesis protein TtcA | Haemophilus | <M><S><E><L><T><Q><L><A><Q><Q><E><K><K><Q><T><Y><N><F><N><K><L><Q><K><R><L><R><R><N><V><G><N><A><I><A><D><F><G><M><I><E><D><G><D><K><V><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><I><L><L><N><L><Q><Q><S><A><P><I><K><F><D><I><V><A><V><N><L><D><Q><K><Q><P><G><F><P><E><H><V><L><P><E><Y><L><E><S><I><G><V><D><Y><K><I><V><Q... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | Q57184 |
B0Y665 | PLB1_ASPFC | Phospholipase B 1 | Aspergillus subgen. Fumigati | <M><K><T><T><T><V><A><C><A><V><A><G><L><L><F><S><C><V><S><G><A><P><D><P><V><H><V><E><I><Q><Q><R><A><L><P><N><A><P><D><G><Y><T><P><S><T><V><G><C><P><A><S><R><P><T><I><R><S><A><A><S><L><S><P><N><E><T><S><W><L><E><T><R><R><G><K><T><T><S><A><M><K><D><F><F><N><H><V><K><I><Q><D><F><D><A><A><G><Y><I><D><R><H><S><S><N><S><S><D... | Catalyzes the release of fatty acids from lysophospholipids.<BOP> | B0Y665 |
Q59J82 | FAD3E_MORAP | Omega-3 fatty acid desaturase 3, endoplasmic reticulum | Mortierella | <M><A><P><P><H><V><V><D><E><Q><V><R><R><R><I><V><V><E><D><E><I><K><S><K><K><Q><F><E><R><N><Y><V><P><M><D><F><T><I><K><E><I><R><D><A><I><P><A><H><L><F><I><R><D><T><T><K><S><I><L><H><V><V><K><D><L><V><T><I><A><I><V><F><Y><C><A><T><F><I><E><T><L><P><S><L><A><L><R><V><P><A><W><I><T><Y><W><I><I><Q><G><T><V><M><V><G><P><W><I... | omega(3) desaturase that uses both 18-carbon and 20-carbon n-6 polyunsaturated fatty acids as substrates.<BOP> | Q59J82 |
B7IH59 | EFP_THEAB | Elongation factor P | Thermosipho | <M><V><D><V><G><S><L><S><K><G><M><Y><I><K><Y><E><G><E><I><Y><R><V><I><D><V><N><K><H><F><R><A><R><G><S><G><L><I><R><T><K><L><K><N><M><S><T><G><L><V><R><E><V><N><F><N><S><G><E><K><V><E><E><A><E><I><T><F><R><K><A><S><Y><I><Y><N><D><G><E><K><Y><Y><F><M><D><N><E><T><F><E><Q><Y><G><I><P><V><S><D><I><E><E><E><K><N><Y><L><V><E... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | B7IH59 |
B0CZ32 | MTNB_LACBS | Methylthioribulose-1-phosphate dehydratase | Laccaria | <M><A><S><Q><D><A><D><A><L><V><T><S><S><D><P><L><H><P><A><N><L><I><P><E><L><C><R><S><F><Y><Q><L><G><W><V><T><G><T><G><G><G><I><C><I><R><T><G><D><K><V><F><I><A><P><S><G><V><Q><K><E><R><I><E><S><T><H><I><F><V><L><P><Y><P><Q><A><A><P><S><P><H><T><D><R><A><F><L><R><R><P><A><M><N><L><K><E><S><A><C><T><P><L><F><W><N><S><F><D... | Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).<BOP> | B0CZ32 |
A7GRL3 | PYRC_BACCN | Dihydroorotase | Bacillus cereus group | <M><N><Y><L><F><K><N><G><R><Y><L><N><E><E><G><T><I><V><A><T><D><L><L><V><Q><D><G><K><I><A><K><I><A><K><N><I><S><A><E><N><A><E><V><I><D><V><N><G><K><L><I><A><P><G><L><V><D><V><H><V><H><L><R><E><P><G><G><E><H><K><E><T><I><E><T><G><T><L><A><A><A><K><G><G><F><T><T><I><C><A><M><P><N><T><R><P><V><P><D><S><K><E><H><M><E><D><L... | Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.<BOP> | A7GRL3 |
B4U7T6 | ACP_HYDS0 | Acyl carrier protein | unclassified Hydrogenobaculum | <M><D><R><E><Q><R><I><K><E><I><I><A><D><Q><L><G><V><E><V><D><K><L><T><P><D><A><K><F><V><E><D><L><G><A><D><S><L><D><V><V><E><L><I><M><S><F><E><E><E><F><N><I><E><I><P><D><E><D><A><E><K><I><K><T><V><G><D><V><I><N><Y><L><N><E><K><L><K> | Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP> | B4U7T6 |
Q6CSI1 | HAT2_KLULA | Histone acetyltransferase type B subunit 2 | Kluyveromyces | <M><T><E><V><E><E><P><E><Q><P><T><T><I><N><E><E><Y><D><L><W><V><S><N><V><P><M><M><Y><D><F><V><S><E><T><R><L><T><W><P><S><L><T><V><Q><W><L><P><T><E><M><Q><P><R><E><V><D><G><Q><Q><L><L><R><Q><E><L><L><I><G><T><L><T><T><D><N><E><P><N><Y><L><K><I><A><A><I><D><L><P><E><N><V><T><S><S><K><P><S><V><S><D><D><A><K><E><N><E><L><S... | Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing.<BOP> | Q6CSI1 |
Q3HRV3 | CGHB_AOTNA | Chorionic gonadotrophin chain beta | Aotus | <M><E><M><L><Q><G><L><L><L><C><L><L><L><S><T><G><G><A><W><A><S><N><E><P><L><R><P><L><C><R><P><T><H><A><I><L><A><A><E><K><E><G><C><P><V><C><V><A><F><N><T><T><I><C><A><G><Y><C><S><S><M><V><R><V><L><Q><T><V><M><P><P><L><P><Q><L><V><C><N><Y><H><E><L><R><F><T><S><V><R><L><P><G><C><R><R><G><V><N><P><V><V><Y><F><P><V><A><V><S... | Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.<BOP> | Q3HRV3 |
A4STJ8 | GPPA_AERS4 | pppGpp-5'-phosphohydrolase | Aeromonas | <M><H><N><S><P><L><Y><A><A><I><D><L><G><S><N><S><F><H><M><L><V><V><R><E><V><A><G><A><L><R><T><V><T><K><V><K><R><K><V><R><L><A><A><G><L><D><P><E><F><R><L><S><R><A><A><M><E><R><G><W><D><C><L><R><L><F><S><E><Q><L><Q><D><I><P><A><D><N><I><R><V><V><G><T><A><T><L><R><L><A><T><N><V><D><E><F><L><S><E><A><E><R><V><L><N><H><S><I... | Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activ... | A4STJ8 |
B1KI61 | ACPS_SHEWM | 4'-phosphopantetheinyl transferase AcpS | Shewanella | <M><I><V><G><L><G><T><D><I><A><E><I><E><R><I><E><Q><K><V><P><A><A><G><D><I><K><G><L><E><S><C><R><L><A><K><R><V><L><T><E><P><E><M><A><I><F><I><A><S><K><Q><P><A><R><Y><L><A><K><R><F><A><A><K><E><A><A><A><K><A><L><G><T><G><I><G><R><G><V><S><F><Q><H><I><E><I><S><N><D><T><N><G><A><P><L><I><S><F><N><G><G><A><A><D><R><L><A><S... | Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP> | B1KI61 |
B0B888 | RL6_CHLT2 | 50S ribosomal protein L6 | Chlamydia | <M><S><R><K><A><R><D><P><I><V><L><P><Q><G><V><E><V><S><I><Q><N><D><E><I><S><V><K><G><P><K><G><S><L><T><Q><V><L><A><K><E><V><E><I><A><V><K><G><N><E><V><F><V><A><P><A><A><H><V><V><D><R><P><G><R><M><Q><G><L><Y><W><A><L><I><A><N><M><V><K><G><V><H><T><G><F><E><K><R><L><E><M><I><G><V><G><F><R><A><A><V><Q><G><S><L><L><D><L><S... | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP> | B0B888 |
P21236 | ERM_STREE | Macrolide-lincosamide-streptogramin B resistance protein | Streptococcus | <M><N><K><N><I><K><Y><S><Q><N><F><L><T><S><E><K><V><L><N><Q><I><I><K><Q><L><N><L><K><E><T><D><T><V><Y><E><I><G><T><G><K><G><H><L><T><T><K><L><A><K><I><S><K><Q><V><T><S><I><E><L><D><S><H><L><F><N><L><S><S><E><K><L><K><L><N><I><R><V><T><L><I><H><Q><D><I><L><Q><F><Q><F><P><N><K><Q><R><Y><K><I><V><G><S><I><P><Y><H><L><S><T... | This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.<BOP> | P21236 |
Q9HXX3 | CSD_PSEAE | Probable cysteine desulfurase | Pseudomonas | <M><S><L><P><S><P><W><R><A><D><F><P><A><F><S><A><F><A><A><E><G><L><T><Y><L><D><S><A><A><T><A><Q><K><P><Q><A><V><L><D><A><L><N><G><Y><Y><L><G><G><A><A><N><V><H><R><A><Q><H><V><P><G><E><R><A><T><R><A><F><E><A><A><R><S><R><V><A><H><W><L><H><A><G><N><P><A><E><V><L><F><T><R><G><T><T><E><A><I><N><L><V><A><Y><G><L><E><R><H><F... | Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.<BOP> | Q9HXX3 |
Q57M35 | NUOI_SALCH | NDH-1 subunit I | Salmonella | <M><T><L><K><E><L><L><V><G><F><G><T><Q><V><R><S><I><W><M><I><G><L><H><A><F><A><K><R><E><T><R><M><Y><P><E><E><P><V><Y><L><P><P><R><Y><R><G><R><I><V><L><T><R><D><P><D><G><E><E><R><C><V><A><C><N><L><C><A><V><A><C><P><V><G><C><I><S><L><Q><K><A><E><T><K><D><G><R><W><Y><P><E><F><F><R><I><N><F><S><R><C><I><F><C><G><L><C><E><E... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q57M35 |
Q82ZD5 | KGUA_ENTFA | GMP kinase | Enterococcus | <M><S><E><R><G><L><L><I><V><L><S><G><P><S><G><V><G><K><G><T><V><R><K><A><I><F><D><S><E><E><N><D><F><Q><Y><S><I><S><M><T><T><R><K><Q><R><E><G><E><V><D><G><V><D><Y><Y><F><R><S><R><E><E><F><E><A><M><I><E><A><G><E><M><L><E><Y><A><E><Y><V><G><N><Y><Y><G><T><P><L><T><Y><V><N><Q><T><L><D><E><G><K><D><V><F><L><E><I><E><V><Q><G... | Essential for recycling GMP and indirectly, cGMP.<BOP> | Q82ZD5 |
A1UN98 | SYS_MYCSK | Seryl-tRNA(Ser/Sec) synthetase | unclassified Mycobacterium | <M><I><D><L><K><F><L><R><E><N><P><D><A><V><R><A><S><Q><R><S><R><G><E><D><P><A><L><V><D><A><L><L><D><A><D><A><A><R><R><A><A><V><S><A><A><D><N><L><R><A><E><Q><K><A><A><S><K><K><V><G><K><A><S><P><E><E><R><P><A><L><L><T><Q><A><K><E><L><A><E><Q><V><K><A><A><E><A><A><Q><A><D><A><D><R><T><F><T><A><A><H><M><A><I><S><N><V><V><I... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP> | A1UN98 |
A9AC50 | GATB_BURM1 | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Burkholderia cepacia complex | <M><S><T><Q><W><E><V><V><I><G><L><E><T><H><A><Q><L><S><T><V><S><K><I><F><S><G><A><S><T><Q><F><G><A><E><P><N><T><Q><A><C><P><V><D><L><A><L><P><G><V><L><P><V><L><N><R><G><A><V><E><R><A><I><R><F><G><L><A><I><G><A><T><I><A><P><R><S><I><F><A><R><K><N><Y><F><Y><P><D><L><P><K><G><Y><Q><I><S><Q><Y><E><I><P><V><V><Q><G><G><A><I... | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | A9AC50 |
Q5P2G2 | TRPD_AROAE | Anthranilate phosphoribosyltransferase | Aromatoleum | <M><T><I><T><A><Q><E><A><L><Q><R><T><I><D><H><R><E><I><F><Y><D><E><M><L><S><L><M><R><Q><I><M><A><G><E><I><S><P><L><M><T><A><A><I><I><T><G><L><R><V><K><K><E><T><I><G><E><I><T><A><A><A><T><V><M><R><E><L><A><T><K><V><T><V><P><G><P><D><R><N><F><L><D><V><V><G><T><G><G><D><G><A><N><T><F><N><I><S><T><T><T><I><F><V><A><A><A><A... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q5P2G2 |
Q5EA36 | RBM14_BOVIN | RNA-binding motif protein 14 | Bos | <M><K><I><F><V><G><N><V><D><G><A><D><T><T><P><E><E><L><A><A><L><F><A><P><Y><G><T><V><M><S><C><A><V><M><K><Q><F><A><F><V><H><M><R><E><N><A><G><A><V><R><A><I><E><A><L><H><G><H><E><L><R><P><G><R><A><L><V><V><E><M><S><R><P><R><P><L><N><T><W><K><I><F><V><G><N><V><S><A><A><C><T><S><Q><E><L><R><S><L><F><E><R><R><G><R><V><I><E... | May function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the ... | Q5EA36 |
Q7WGT9 | UBIG_BORBR | 3-demethylubiquinone 3-O-methyltransferase | Bordetella | <M><T><T><A><T><Q><S><S><A><P><G><V><N><V><D><Q><A><E><V><E><K><F><S><A><L><A><A><R><W><W><D><P><E><S><E><F><K><P><L><H><A><I><N><P><L><R><L><G><W><I><Q><E><T><A><G><S><L><S><G><K><R><V><L><D><V><G><C><G><G><G><I><L><S><E><S><M><A><V><A><G><A><Q><V><T><G><I><D><L><A><E><K><S><L><K><I><A><R><L><H><G><L><E><S><G><V><K><V... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q7WGT9 |
Q8X6U5 | UGPC_ECO57 | sn-glycerol-3-phosphate import ATP-binding protein UgpC | Escherichia | <M><A><G><L><K><L><Q><A><V><T><K><S><W><D><G><K><T><Q><V><I><K><P><L><T><L><D><V><A><D><G><E><F><I><V><M><V><G><P><S><G><C><G><K><S><T><L><L><R><M><V><A><G><L><E><R><V><T><E><G><D><I><C><I><N><D><Q><R><V><T><E><M><E><P><K><D><R><G><I><A><M><V><F><Q><N><Y><A><L><Y><P><H><M><S><V><E><E><N><M><A><W><G><L><K><I><R><G><M><G... | Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system.<BOP> | Q8X6U5 |
P0A9E1 | ARAC_ECO57 | Arabinose operon regulatory protein | Escherichia | <M><A><E><A><Q><N><D><P><L><L><P><G><Y><S><F><N><A><H><L><V><A><G><L><T><P><I><E><A><N><G><Y><L><D><F><F><I><D><R><P><L><G><M><K><G><Y><I><L><N><L><T><I><R><G><Q><G><V><V><K><N><Q><G><R><E><F><V><C><R><P><G><D><I><L><L><F><P><P><G><E><I><H><H><Y><G><R><H><P><E><A><R><E><W><Y><H><Q><W><V><Y><F><R><P><R><A><Y><W><H><E><W... | Transcription factor that regulates the expression of several genes involved in the transport and metabolism of L-arabinose.<BOP> | P0A9E1 |
P33048 | CASB_CAPHI | Beta-casein | Capra | <M><K><V><L><I><L><A><C><L><V><A><L><A><I><A><R><E><Q><E><E><L><N><V><V><G><E><T><V><E><S><L><S><S><S><E><E><S><I><T><H><I><N><K><K><I><E><K><F><Q><S><E><E><Q><Q><Q><T><E><D><E><L><Q><D><K><I><H><P><F><A><Q><A><Q><S><L><V><Y><P><F><T><G><P><I><P><N><S><L><P><Q><N><I><L><P><L><T><Q><T><P><V><V><V><P><P><F><L><Q><P><E><I... | Important role in determination of the surface properties of the casein micelles.<BOP> | P33048 |
Q9XFB6 | NAS8_HORVU | S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 8 | Hordeum | <M><D><A><Q><N><K><E><V><D><A><L><V><Q><K><I><T><G><L><H><A><A><I><A><K><L><P><S><L><S><P><S><P><D><V><D><A><L><F><T><D><L><V><T><A><C><V><P><P><S><P><V><D><V><T><K><L><G><S><E><A><Q><E><M><R><E><G><L><I><R><L><C><S><E><A><E><G><K><L><E><A><H><Y><S><D><M><L><A><A><F><D><N><P><L><D><H><L><G><M><F><P><Y><Y><S><N><Y><I><N... | Synthesizes nicotianamine, a polyamine that is the first intermediate in the synthesis of the phytosiderophores of the mugineic acid type found in gramineae which serve as a sensor for the physiological iron status within the plant, and/or might be involved in the transport of iron.<BOP> | Q9XFB6 |
Q5WFK4 | RPOZ_ALKCK | Transcriptase subunit omega | Alkalihalobacillus | <M><L><Y><P><S><I><D><N><L><L><E><K><L><D><S><K><Y><S><L><V><T><V><S><A><R><R><A><R><E><M><K><E><D><S><A><R><V><P><L><V><E><K><P><K><S><Y><K><F><V><G><I><A><L><E><E><I><V><N><D><Q><L><T><K><R><V><P><K><E><E><Q> | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP> | Q5WFK4 |
B4TKL2 | RL2_SALHS | 50S ribosomal protein L2 | Salmonella | <M><A><V><V><K><C><K><P><T><S><P><G><R><R><H><V><V><K><V><V><N><P><E><L><H><K><G><K><P><F><A><P><L><V><E><K><N><S><K><S><G><G><R><N><N><N><G><R><I><T><T><R><H><I><G><G><G><H><K><Q><A><Y><R><I><V><D><F><K><R><N><K><D><G><I><P><A><V><V><E><R><L><E><Y><D><P><N><R><S><A><N><I><A><L><V><L><Y><K><D><G><E><R><R><Y><I><L><A><P... | One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<... | B4TKL2 |
A8EU90 | QUEA_ALIB4 | Queuosine biosynthesis protein QueA | Aliarcobacter | <M><L><D><P><L><K><T><S><S><Y><D><Y><N><L><P><K><N><Q><I><A><T><Y><P><V><T><P><A><D><S><A><K><L><L><I><F><N><R><S><T><N><T><I><I><H><S><T><F><K><D><I><L><E><F><L><P><N><D><L><S><I><F><L><N><D><T><K><V><I><K><A><R><I><F><G><V><K><D><S><G><G><Q><I><E><L><L><L><N><K><P><L><F><M><D><R><Y><L><V><M><I><R><G><K><V><R><V><G><T... | Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).<BOP> | A8EU90 |
Q2KZ16 | GCH4_BORA1 | GTP cyclohydrolase FolE2 | Bordetella | <M><N><S><P><I><D><P><A><I><V><M><P><D><V><Q><S><S><A><D><T><R><H><I><Q><I><Q><R><V><G><I><R><G><V><R><H><P><M><L><V><V><A><G><D><G><S><A><Q><A><T><V><A><N><W><T><L><T><V><A><L><P><A><E><E><K><G><T><H><M><S><R><F><V><A><L><L><E><K><Y><R><A><T><P><M><T><P><A><L><F><S><Q><M><A><R><E><M><L><P><L><L><H><A><E><R><G><D><L><T... | Converts GTP to 7,8-dihydroneopterin triphosphate.<BOP> | Q2KZ16 |
B0K7K7 | KTHY_THEP3 | dTMP kinase | Thermoanaerobacter | <M><K><G><K><F><I><S><F><E><G><I><D><G><C><G><K><T><T><Q><I><K><F><L><E><E><Y><L><L><K><Q><G><Y><N><I><L><V><L><R><E><P><G><G><T><K><V><G><E><K><V><R><D><I><L><L><D><K><N><N><F><I><S><P><V><T><E><M><L><L><Y><A><S><S><R><A><Q><L><V><E><E><K><I><L><P><A><I><E><E><G><K><I><V><L><L><D><R><F><V><D><S><S><Y><V><Y><Q><G><Y><A... | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP> | B0K7K7 |
Q07VS6 | YIDC_SHEFN | Membrane protein YidC | Shewanella | <M><E><S><Q><R><N><I><L><L><I><G><L><L><F><V><S><F><L><M><W><Q><Q><W><Q><T><D><K><A><P><K><P><A><T><A><Q><T><V><T><Q><T><N><A><A><S><Q><H><S><A><D><V><P><E><A><D><I><S><G><V><P><V><E><L><P><A><N><K><N><L><I><S><V><K><T><D><Q><L><D><I><K><I><S><P><I><G><G><D><I><V><Y><A><A><L><V><E><H><K><R><E><I><D><S><S><D><P><F><V><I... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | Q07VS6 |
Q15648 | MED1_HUMAN | p53 regulatory protein RB18A | Homo | <M><K><A><Q><G><E><T><E><E><S><E><K><L><S><K><M><S><S><L><L><E><R><L><H><A><K><F><N><Q><N><R><P><W><S><E><T><I><K><L><V><R><Q><V><M><E><K><R><V><V><M><S><S><G><G><H><Q><H><L><V><S><C><L><E><T><L><Q><K><A><L><K><V><T><S><L><P><A><M><T><D><R><L><E><S><I><A><R><Q><N><G><L><G><S><H><L><S><A><S><G><T><E><C><Y><I><T><S><D><M... | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters... | Q15648 |
A5EXT4 | IHFA_DICNV | Integration host factor subunit alpha | Dichelobacter | <M><T><L><T><K><A><D><I><V><E><A><I><I><A><Q><I><G><I><P><R><P><E><A><R><E><I><V><D><D><L><F><E><E><I><R><S><C><L><A><T><G><E><P><V><K><L><S><G><F><G><N><F><E><L><R><D><K><N><Q><R><P><G><R><N><P><K><T><G><E><E><I><P><I><T><A><R><R><V><V><S><F><K><A><G><Q><K><L><K><A><R><V><A><E><S><K><P><R><G> | This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP> | A5EXT4 |
Q9RED7 | RLMB_BURSP | 23S rRNA Gm2251 2'-O-methyltransferase | Burkholderia | <M><P><R><L><K><L><L><H><G><F><H><A><I><T><A><R><L><R><A><F><P><A><T><V><N><E><V><W><Y><D><P><A><R><Q><D><A><R><M><R><A><F><L><H><L><A><A><S><A><N><A><R><L><I><A><A><D><A><S><R><L><N><A><L><S><G><E><K><R><H><Q><G><V><V><A><R><V><T><E><A><T><R><A><H><S><L><E><T><L><L><D><T><I><E><G><Q><P><L><L><L><A><L><D><G><V><T><D><P... | Specifically methylates the ribose of guanosine 2251 in 23S rRNA.<BOP> | Q9RED7 |
Q9MAX3 | SUT12_ARATH | Sulfate transporter 1.2 | Arabidopsis | <M><S><S><R><A><H><P><V><D><G><S><P><A><T><D><G><G><H><V><P><M><K><P><S><P><T><R><H><K><V><G><I><P><P><K><Q><N><M><F><K><D><F><M><Y><T><F><K><E><T><F><F><H><D><D><P><L><R><D><F><K><D><Q><P><K><S><K><Q><F><M><L><G><L><Q><S><V><F><P><V><F><D><W><G><R><N><Y><T><F><K><K><F><R><G><D><L><I><S><G><L><T><I><A><S><L><C><I><P><Q... | High-affinity H(+)/sulfate cotransporter that mediates the uptake of the environmental sulfate by plant roots. Plays a central role in the regulation of sulfate assimilation. Unable to transport molybdate.<BOP> | Q9MAX3 |
Q4FNN5 | MIAB_PELUB | tRNA-i(6)A37 methylthiotransferase | Candidatus Pelagibacter | <M><L><K><K><I><F><I><K><T><F><G><C><Q><M><N><E><Y><D><S><N><R><I><F><D><T><V><K><K><I><G><F><E><K><T><E><K><Y><E><D><A><N><C><Y><L><L><N><T><C><H><I><R><D><K><A><K><E><K><V><Y><H><E><I><G><R><V><K><K><I><F><R><E><K><K><K><P><I><V><V><V><A><G><C><V><A><Q><A><E><N><Q><E><M><L><K><R><E><P><Y><I><D><I><V><I><G><P><Q><S><Y... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | Q4FNN5 |
P39461 | FUMC_SACS2 | Iron-independent fumarase | Saccharolobus | <M><K><Y><T><D><T><A><P><K><L><F><M><N><T><G><T><K><F><P><R><R><I><I><W><S><M><G><V><L><K><K><S><C><A><K><V><N><A><D><L><G><L><L><D><K><K><I><A><D><S><I><I><K><A><S><D><D><L><I><D><G><K><L><D><D><K><I><V><L><D><V><F><Q><T><G><S><G><T><G><L><N><M><N><V><N><E><V><I><A><E><V><A><S><S><Y><S><N><L><K><V><H><P><N><D><H><V><N... | Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.<BOP> | P39461 |
A9MXE2 | ILVD_SALPB | Dihydroxy-acid dehydratase | Salmonella | <M><P><K><Y><R><S><A><T><T><T><Y><G><R><N><M><A><G><A><R><A><L><W><R><A><T><G><M><T><D><S><D><F><G><K><P><I><I><A><V><V><N><S><F><T><Q><F><V><P><G><H><V><H><L><R><D><L><G><K><L><V><A><E><Q><I><E><A><S><G><G><V><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><G><G><M><L><Y><S><L><P><S><R><E><L><I><A><D><S><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | A9MXE2 |
Q06GU7 | CCSA_DRIGR | Cytochrome c biogenesis protein CcsA | Drimys | <M><I><F><A><T><L><E><H><I><L><T><H><I><S><F><S><I><I><S><I><V><I><T><I><Q><L><I><D><L><L><V><Y><Q><I><V><G><I><C><D><S><S><E><K><G><I><I><A><T><F><F><C><I><T><G><L><L><I><T><R><W><I><Y><S><R><H><F><P><L><S><D><L><Y><E><S><L><M><F><L><S><W><S><F><S><I><I><H><M><V><P><K><A><G><N><H><K><N><D><L><S><A><I><T><G><P><S><A><I... | Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.<BOP> | Q06GU7 |
A0MTQ2 | BAPA_SPHMI | Beta-peptidyl aminopeptidase BapA beta subunit | Sphingosinicella | <M><H><Y><L><K><F><P><A><I><I><A><G><M><L><L><A><G><A><A><S><A><E><G><P><R><A><R><D><L><G><V><P><F><A><G><K><P><G><A><N><N><A><I><T><D><V><A><G><V><E><V><G><Y><V><S><L><I><S><G><E><G><K><L><E><R><G><K><G><P><V><R><T><G><V><T><A><V><L><P><R><G><K><E><S><R><T><P><V><Y><A><G><W><E><T><S><N><A><A><G><E><M><T><G><T><V><W><L... | Beta-aminopeptidase that can cleave synthetic beta-peptides which consist of backbone-elongated beta-amino acid residues that are not processed by common proteolytic enzymes. Can cleave the beta-peptides beta-homoVal-beta-homoAla-beta-homoLeu and beta-homoAla-beta-homoLeu. Requires a beta-amino acid at the N-terminus o... | A0MTQ2 |
Q9UXW6 | PURL_PYRAB | Phosphoribosylformylglycinamidine synthase subunit II | Pyrococcus | <M><L><P><R><E><E><K><I><I><R><E><R><L><G><R><E><P><N><E><V><E><K><A><M><L><E><V><M><W><S><E><H><V><S><Y><K><S><S><R><K><W><L><K><L><L><P><T><K><N><E><H><V><I><L><G><P><G><E><D><A><G><V><V><K><F><D><E><S><T><W><I><V><I><G><I><E><S><H><N><H><P><S><A><V><E><P><Y><G><G><A><A><T><G><I><G><G><I><V><R><D><I><L><C><M><G><A><R... | Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three su... | Q9UXW6 |
C3PHK3 | GCST_CORA7 | Glycine cleavage system T protein | Corynebacterium | <M><T><D><Y><L><H><S><P><L><H><A><E><H><E><K><L><G><A><T><F><T><P><F><G><P><W><E><M><P><L><K><Y><D><N><E><L><E><E><H><R><A><V><R><N><A><A><G><L><F><D><L><S><H><M><G><E><I><W><V><N><G><P><D><A><A><E><F><L><S><Y><C><F><I><S><N><L><T><T><L><K><E><G><K><A><K><Y><S><M><I><C><A><E><D><G><G><I><I><D><D><L><I><T><Y><R><L><E><E... | The glycine cleavage system catalyzes the degradation of glycine.<BOP> | C3PHK3 |
P61615 | IDI2_SACSH | Type 2 isopentenyl diphosphate isomerase | Saccharolobus | <M><P><D><I><V><N><R><K><V><E><H><V><E><I><A><A><F><E><N><V><D><G><L><S><S><S><T><F><L><N><D><V><I><L><V><H><Q><G><F><P><G><I><S><F><S><E><I><N><T><K><T><K><F><F><R><K><E><I><S><V><P><V><M><V><T><G><M><T><G><G><R><N><E><L><G><R><I><N><K><I><I><A><E><V><A><E><K><F><G><I><P><M><G><V><G><S><Q><R><V><A><I><E><K><A><E><A><R... | Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).<BOP> | P61615 |
D2Y174 | CT15_CONCL | Conotoxin Cal1.1b | Californiconus | <M><R><C><L><P><V><F><I><I><L><L><L><L><A><S><T><A><A><V><D><V><A><G><S><K><L><K><R><R><L><E><R><K><P><Y><Q><G><S><Q><A><Y><V><K><K><T><A><F><G><L><R><L><C><C><K><R><H><H><G><C><H><P><C><G><R><T> | Probable neurotoxin with unknown target. Possibly targets ion channels.<BOP> | D2Y174 |
Q88VD5 | RS15_LACPL | 30S ribosomal protein S15 | Lactiplantibacillus | <M><A><I><S><R><E><K><K><T><E><L><I><N><K><Y><A><R><H><E><G><D><T><G><S><V><E><V><Q><V><A><V><L><T><E><D><I><N><E><L><N><E><H><L><R><V><H><K><K><D><F><H><S><Q><R><G><L><M><K><K><I><G><H><R><R><N><L><L><A><Y><L><R><K><E><D><V><N><R><Y><R><D><L><I><Q><S><L><G><L><R><R> | Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP> | Q88VD5 |
C6DDH0 | CYSD_PECCP | Sulfate adenylate transferase | Pectobacterium | <M><D><E><K><R><L><T><H><L><R><Q><L><E><A><E><S><I><H><I><I><R><E><V><A><A><E><F><S><N><P><V><M><M><Y><S><I><G><K><D><S><S><V><M><L><H><L><A><R><K><A><F><Y><P><G><S><L><P><F><P><L><L><H><V><D><T><G><W><K><F><R><E><M><Y><E><F><R><D><R><T><A><K><A><Y><G><C><E><L><L><V><H><R><N><P><Q><G><E><A><L><G><I><N><P><F><V><H><G><S... | With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi... | C6DDH0 |
Q47LR8 | FOLD_THEFY | Methenyltetrahydrofolate cyclohydrolase | Thermobifida | <M><T><A><Q><V><L><D><G><K><A><T><A><A><A><I><R><E><E><L><K><E><R><V><A><A><L><R><A><R><G><V><V><P><G><L><G><T><I><L><V><G><D><D><P><G><S><H><A><Y><V><R><G><K><H><R><D><C><A><E><V><G><I><A><S><I><R><K><D><L><P><A><D><A><T><Q><A><D><V><E><A><A><V><A><E><L><N><A><D><P><A><C><T><G><F><I><V><Q><L><P><L><P><R><G><L><D><E><N... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q47LR8 |
Q9KRM5 | METAS_VIBCH | Homoserine transsuccinylase | Vibrio | <M><P><I><R><I><P><D><Q><L><P><A><S><D><V><L><R><N><E><N><I><F><V><M><S><E><S><R><A><S><T><Q><E><I><R><P><L><K><V><L><L><L><N><L><M><P><K><K><I><E><T><E><T><Q><F><L><R><L><L><S><N><S><P><L><Q><V><D><I><E><L><L><R><I><D><D><R><P><S><K><N><T><P><E><E><H><L><N><T><F><Y><R><Q><F><E><L><V><K><N><R><N><F><D><G><L><I><I><T><G... | Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.<BOP> | Q9KRM5 |
Q7TN29 | SMAP2_MOUSE | Stromal membrane-associated protein 1-like | Mus | <M><T><G><K><S><V><K><D><V><D><R><Y><Q><A><V><L><A><N><L><L><L><E><E><D><N><K><F><C><A><D><C><Q><S><K><G><P><R><W><A><S><W><N><I><G><V><F><I><C><I><R><C><A><G><I><H><R><N><L><G><V><H><I><S><R><V><K><S><V><N><L><D><Q><W><T><Q><E><Q><I><Q><C><M><Q><E><M><G><N><G><K><A><N><R><L><Y><E><A><Y><L><P><E><T><F><R><R><P><Q><I><D... | GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network.<BOP> | Q7TN29 |
Q5FB29 | SODC_CAPHI | Superoxide dismutase [Cu-Zn] | Capra | <M><A><T><K><A><V><C><V><L><K><G><D><G><P><V><Q><G><T><I><H><F><E><A><K><G><D><K><V><V><V><T><G><S><I><T><G><L><T><E><G><D><H><G><F><H><V><H><Q><F><G><D><N><T><Q><G><C><T><S><A><G><P><H><F><N><P><L><S><K><K><H><G><G><P><K><D><E><E><R><H><V><G><D><L><G><N><V><K><A><D><K><N><G><V><A><I><V><D><I><V><D><P><L><I><S><L><S><G... | Destroys radicals which are normally produced within the cells and which are toxic to biological systems.<BOP> | Q5FB29 |
C4LBV5 | RL1_TOLAT | 50S ribosomal protein L1 | Tolumonas | <M><A><K><L><T><K><R><M><R><V><I><R><E><K><V><D><A><T><K><E><Y><G><I><T><E><A><V><A><L><L><K><E><L><A><T><A><K><F><V><E><S><V><D><V><A><V><N><L><G><I><D><A><R><K><S><D><Q><N><V><R><G><A><T><V><L><P><N><G><T><G><R><T><V><R><V><A><V><F><T><Q><G><A><N><A><E><A><A><T><A><A><G><A><D><L><V><G><M><E><D><L><A><E><Q><V><K><R><G... | Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP> | C4LBV5 |
Q43831 | RUBB_SECCE | CPN-60 beta | Secale | <P><Q><I><V><N><D><G><V><T><V><A><R><E><V><E><L><E><D><P><V><E><N><I><G><A><K><L><V><R><Q><A><A><A><K><T><N><D><L><A><G><D><G><T><T><T><S><V><V><L><A><Q><G><L><I><A><E><G><V><K><V><I><A><A><G><A><N><P><V><Q><I><T><R><G><I><E><K><T><A><K><A><L><V><L><E><L><K><K><M><S><K><E><V><E><D><S><E><L><A><D><V><A><A><V><S><A><G><N... | This protein binds RuBisCO small and large subunits and is implicated in the assembly of the enzyme oligomer.<BOP> | Q43831 |
Q9BQ66 | KR412_HUMAN | Ultrahigh sulfur keratin-associated protein 4.12 | Homo | <M><V><N><S><C><C><G><S><V><C><S><D><Q><G><C><G><L><E><N><C><C><R><P><S><C><C><Q><T><T><C><C><R><T><T><C><C><R><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><S><V><C><C><Q><P><T><C><C><R><P><S><C><C><Q><T><T><C><C><R><T><T><C><C><R><P><S><C><C><V><S><S><C><C><R><P><Q><C><C><Q><S><V><C><C><Q><P><T><C><C><R><P><S><C><C><Q... | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of ha... | Q9BQ66 |
P38337 | SHG1_YEAST | Set1C component SHG1 | Saccharomyces | <M><A><Y><N><Q><E><D><S><K><R><L><S><D><K><Y><K><K><E><G><H><F><D><K><L><K><R><E><I><L><S><N><P><W><N><N><T><E><E><N><S><E><S><F><E><Q><A><L><R><K><R><V><A><S><T><V><K><E><M><V><N><E><D><E><E><L><I><F><K><N><R><G><L><T><S><A><L><I><E><S><Q><L><V><K><D><N><Y><L><K><L><G><S><K><M><E><G><D><N><G><D><G><E><K><K><F><D><L><D... | The COMPASS (Set1C) complex specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.<BOP> | P38337 |
G0SEQ5 | NOC1_CHATD | Nucleolar complex protein 1 | Thermochaetoides | <M><G><L><K><R><A><A><R><Q><Q><R><D><I><G><K><P><A><F><D><E><E><A><L><V><E><L><T><G><K><I><D><K><T><L><P><A><V><E><Q><K><I><A><G><K><R><K><R><Q><N><A><S><D><D><G><R><G><S><K><R><R><Q><T><H><P><T><E><A><E><E><H><R><D><S><H><A><A><A><K><D><K><A><N><R><I><L><L><E><E><I><I><A><L><G><G><D><E><K><D><L><E><L><V><A><D><V><D><S... | Required for 60S ribosomal subunit synthesis.<BOP> | G0SEQ5 |
A6W504 | TSAD_KINRD | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Kineococcus | <M><I><V><L><G><V><E><S><S><C><D><E><T><G><V><G><L><V><S><E><G><V><L><L><G><D><A><L><A><S><S><M><D><A><H><A><R><F><G><G><V><V><P><E><V><A><A><R><A><H><L><E><A><I><V><P><V><M><H><E><A><L><G><K><A><G><L><D><L><A><D><V><D><A><V><A><V><T><A><G><P><G><L><S><T><A><V><Q><V><G><L><A><S><A><K><A><L><A><F><A><L><G><K><P><L><Y><G... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | A6W504 |
A6URS6 | NAC_METVS | Nascent polypeptide-associated complex protein | Methanococcus | <M><F><P><G><G><K><M><N><P><R><M><M><K><Q><M><Q><K><M><M><K><D><F><G><M><D><S><E><D><L><K><A><V><K><V><T><I><E><L><E><D><K><I><M><V><F><D><K><P><K><V><Q><V><M><D><M><M><G><T><K><T><Y><T><I><S><G><R><S><K><N><T><S><K><T><A><E><K><I><E><D><T><E><V><K><V><E><V><T><E><E><D><I><E><M><V><A><T><Q><C><N><V><S><K><E><E><A><K><T... | Contacts the emerging nascent chain on the ribosome.<BOP> | A6URS6 |
A6UWT5 | CFBA_META3 | Sirohydrochlorin nickelchelatase | Methanococcus | <M><E><A><L><V><L><L><G><H><G><S><R><L><P><Y><S><K><E><I><V><G><K><V><A><E><K><I><K><E><K><N><I><Y><D><I><V><E><I><G><M><M><E><F><N><E><P><T><I><P><Q><T><I><N><K><V><I><A><E><G><A><K><K><I><I><I><V><P><V><F><L><A><H><G><N><H><T><K><R><D><I><P><Q><I><L><G><L><I><E><C><E><E><H><H><H><E><G><E><G><G><H><H><H><H><H><H><H><H... | Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic m... | A6UWT5 |
P59250 | PLSY2_OCEIH | Lysophosphatidic acid synthase 2 | Oceanobacillus | <M><D><Y><V><I><F><G><L><V><A><Y><L><L><G><S><I><P><S><A><L><I><V><G><K><V><G><Y><N><I><D><I><R><E><H><G><S><G><N><L><G><A><T><N><T><F><R><I><L><G><T><K><A><G><S><I><V><T><L><A><D><I><L><K><G><T><L><A><T><V><L><P><Q><L><F><D><A><N><V><Y><V><L><A><I><G><L><L><A><V><V><G><H><M><Y><P><I><F><A><K><F><R><G><G><K><A><V><A><T... | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP> | P59250 |
A7N992 | RSMG_FRATF | 16S rRNA 7-methylguanosine methyltransferase | Francisella | <M><D><I><M><K><D><K><I><R><Q><A><L><S><E><L><D><I><L><A><T><E><V><Q><I><D><Q><W><L><D><Y><L><K><L><L><E><K><W><N><K><V><Y><N><M><T><A><I><K><N><I><D><E><M><L><V><K><H><L><F><D><S><L><A><V><A><K><Y><I><K><G><D><S><T><V><D><V><G><T><G><G><G><L><P><G><V><V><L><A><I><L><Y><P><Q><H><Q><F><T><L><V><D><S><V><G><K><K><I><M><F... | Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.<BOP> | A7N992 |
Q30Y14 | RL20_OLEA2 | 50S ribosomal protein L20 | Oleidesulfovibrio | <M><R><V><K><R><G><M><A><T><H><R><R><H><K><K><Y><L><K><M><A><K><G><Y><R><G><G><R><S><K><L><Y><R><T><A><R><E><A><V><E><R><S><L><A><Y><S><T><R><D><R><K><V><R><K><R><E><F><R><K><L><W><I><L><R><I><N><A><A><A><R><E><N><G><V><S><Y><S><K><F><I><H><G><L><A><L><A><G><I><E><L><N><R><K><V><L><A><D><L><A><V><R><E><K><E><D><F><A><K... | Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP> | Q30Y14 |
A9WFP3 | EFTU_CHLAA | Elongation factor Tu | Chloroflexus | <M><A><K><Q><K><F><E><R><T><K><P><H><I><N><V><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><K><V><L><S><L><K><G><A><A><Q><F><M><A><Y><D><Q><I><D><N><A><P><E><E><R><A><R><G><I><T><I><A><I><R><H><V><E><Y><Q><T><D><K><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | A9WFP3 |
Q1QLB0 | LOLD_NITHX | Lipoprotein-releasing system ATP-binding protein LolD | Nitrobacter | <M><E><Q><G><A><K><E><I><P><V><V><Y><L><H><D><I><R><R><Q><Y><T><Q><G><E><T><K><L><T><I><L><D><G><T><K><L><A><L><W><A><G><Q><S><V><A><L><V><A><P><S><G><S><G><K><S><T><L><L><H><I><A><G><L><L><E><S><P><D><A><G><E><V><Y><I><G><G><T><A><T><S><G><L><S><D><V><E><R><T><R><I><R><R><T><D><I><G><F><V><Y><Q><S><H><R><L><L><P><E><F... | Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.<BOP> | Q1QLB0 |
Q5JEV6 | ENO_THEKO | 2-phosphoglycerate dehydratase | Thermococcus | <M><E><N><P><F><E><I><T><N><V><I><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><E><V><Y><T><P><I><S><M><G><R><A><A><V><P><S><G><A><S><T><G><T><H><E><A><L><E><L><R><D><G><G><S><R><Y><H><G><K><G><V><R><R><A><V><E><N><V><N><K><I><I><A><P><E><I><I><G><M><D><V><T><W><Q><R><D><I><D><T><L><M><L><E><L><D><G><T><E><N><K><S><N><L... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP> | Q5JEV6 |
A7HZM1 | RL6_CAMHC | 50S ribosomal protein L6 | Campylobacter | <M><S><R><I><G><K><K><P><V><A><I><P><S><G><I><E><V><K><V><D><G><N><V><L><K><F><K><K><G><N><A><Q><K><E><L><D><T><K><N><H><V><D><V><K><V><E><D><G><K><V><E><F><S><P><K><G><E><D><R><Q><S><M><A><F><W><G><T><Y><R><A><L><A><H><N><I><V><V><G><L><T><D><G><F><S><K><Q><L><E><I><N><G><V><G><Y><K><A><A><M><K><G><K><I><L><E><L><T><L... | This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP> | A7HZM1 |
Q58924 | OGT_METJA | O-6-methylguanine-DNA-alkyltransferase | Methanocaldococcus | <M><I><I><Q><I><E><E><Y><F><I><G><M><I><F><K><G><N><Q><L><V><R><N><T><I><P><L><R><R><E><E><I><F><N><F><M><D><G><E><V><V><S><N><P><E><D><E><H><L><K><V><A><E><I><I><L><K><L><Y><F><A><E><I><D><D><K><K><V><R><E><L><I><S><Y><K><L><E><V><P><E><F><T><K><K><V><L><D><I><V><K><D><I><E><F><G><K><T><L><T><Y><G><D><I><A><K><K><L><N... | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inac... | Q58924 |
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