accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P92939
ECA1_ARATH
Calcium-transporting ATPase 1, endoplasmic reticulum-type
Arabidopsis
<M><G><K><G><S><E><D><L><V><K><K><E><S><L><N><S><T><P><V><N><S><D><T><F><P><A><W><A><K><D><V><A><E><C><E><E><H><F><V><V><S><R><E><K><G><L><S><S><D><E><V><L><K><R><H><Q><I><Y><G><L><N><E><L><E><K><P><E><G><T><S><I><F><K><L><I><L><E><Q><F><N><D><T><L><V><R><I><L><L><A><A><A><V><I><S><F><V><L><A><F><F><D><G><D><E><G><G><E...
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the endoplasmic reticulum lumen. Also regulates manganese ion homeostasis by pumping it into endomembrane compartments. Can also transport zinc.<BOP>
P92939
B0BRD0
MURQ_ACTPJ
N-acetylmuramic acid 6-phosphate lyase
Actinobacillus
<M><S><E><K><N><L><L><T><A><L><S><K><M><I><T><E><Q><R><N><P><N><S><M><N><I><D><Q><L><S><A><L><E><L><V><K><V><I><N><Q><E><D><K><Q><V><P><L><A><V><E><K><C><L><A><Q><I><A><Q><A><V><E><K><I><V><Q><A><F><Q><N><G><G><R><L><V><Y><I><G><A><G><T><S><G><R><L><G><V><L><D><A><S><E><C><P><P><T><Y><G><V><S><S><E><M><V><V><G><I><I><A...
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus...
B0BRD0
A4G4Y1
KTHY_HERAR
dTMP kinase
Herminiimonas
<M><T><K><A><K><F><I><T><F><E><G><I><D><G><A><G><K><S><T><H><L><S><F><V><A><D><L><L><R><A><S><K><K><N><V><V><V><T><R><E><P><G><G><T><S><L><G><E><A><L><R><T><I><L><L><H><E><K><M><H><L><E><T><E><A><L><L><M><F><A><A><R><R><E><H><I><A><Q><L><I><E><P><A><L><A><R><G><D><W><V><I><S><D><R><F><T><D><A><T><F><A><Y><Q><G><G><G><R...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
A4G4Y1
P0DMZ2
STX_DOFAR
Da I
Dofleinia
<A><G><G><K><A><T><C><C><P><C><F><M><C><S><Y><T><A><G><C><P><W><G><Q><C><A><H><H><C><G><C><D>
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.<BOP>
P0DMZ2
P80108
PHLD_HUMAN
Glycosyl-phosphatidylinositol-specific phospholipase D
Homo
<M><S><A><F><R><L><W><P><G><L><L><I><M><L><G><S><L><C><H><R><G><S><P><C><G><L><S><T><H><V><E><I><G><H><R><A><L><E><F><L><Q><L><H><N><G><R><V><N><Y><R><E><L><L><L><E><H><Q><D><A><Y><Q><A><G><I><V><F><P><D><C><F><Y><P><S><I><C><K><G><G><K><F><H><D><V><S><E><S><T><H><W><T><P><F><L><N><A><S><V><H><Y><I><R><E><N><Y><P><L><P...
This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.<BOP>
P80108
Q5L5F4
AROA_CHLAB
5-enolpyruvylshikimate-3-phosphate synthase
Chlamydia
<M><L><A><Y><K><I><S><P><S><S><I><S><G><R><V><S><V><P><P><S><K><S><H><T><L><R><A><I><F><W><A><S><V><A><Q><G><T><S><I><I><H><H><A><L><A><S><P><D><S><E><A><M><I><Q><A><C><K><Q><L><G><A><K><I><L><K><K><S><T><H><L><E><I><T><G><T><P><H><L><I><L><P><K><N><T><T><I><N><A><G><S><S><G><I><V><F><R><F><F><T><A><L><A><A><I><F><S><E...
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP>
Q5L5F4
C3N5P4
SPEE_SULIA
Spermidine synthase
Sulfolobus
<M><F><G><W><H><W><L><L><E><W><Q><T><P><Y><E><F><H><G><H><L><I><E><K><V><F><A><E><E><K><T><P><Y><Q><H><V><T><L><V><E><F><T><R><F><G><K><G><L><I><I><D><G><K><V><Q><S><T><L><Y><D><E><H><I><Y><H><E><L><L><V><H><P><L><L><L><S><L><P><K><P><P><K><N><V><L><I><L><G><G><G><E><G><A><T><L><R><E><V><L><K><Y><K><S><V><E><K><A><V><M...
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.<BOP>
C3N5P4
C3JY55
CRCB_PSEFS
Putative fluoride ion transporter CrcB
Pseudomonas
<M><F><K><T><I><L><A><V><S><A><A><G><I><A><G><T><L><L><R><F><A><A><G><T><W><V><S><A><N><W><P><K><H><F><Y><A><A><T><L><A><V><N><L><V><G><C><L><I><I><G><L><L><Y><G><W><F><L><L><R><P><E><V><P><I><E><I><R><A><G><L><I><V><G><F><V><G><G><L><T><T><F><S><S><F><S><L><D><T><L><R><L><L><E><S><G><Q><A><L><I><A><F><G><Y><L><G><I><S...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
C3JY55
Q6NK10
PDXT_CORDI
Pyridoxal 5'-phosphate synthase glutaminase subunit
Corynebacterium
<M><V><I><G><V><L><T><L><Q><G><G><F><A><E><H><I><A><I><L><E><S><L><G><V><E><H><R><R><V><R><V><P><N><D><L><L><G><L><D><G><L><I><I><P><G><G><E><S><T><V><M><D><K><L><A><R><A><F><D><L><A><E><P><L><R><A><A><I><N><N><G><L><P><V><F><A><T><C><A><G><L><I><Y><L><G><T><V><E><N><P><A><K><G><Q><Q><T><L><G><C><L><D><V><V><V><R><R><N...
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP>
Q6NK10
Q6EW68
PSBA_NYMAL
Photosystem II Q(B) protein
Nymphaea
<M><T><A><I><L><E><R><R><E><S><T><S><L><W><G><R><F><C><N><W><V><T><S><T><E><N><R><L><Y><I><G><W><F><G><V><L><M><I><P><T><L><L><T><A><T><S><V><F><I><I><A><F><I><A><A><P><P><V><D><I><D><G><I><R><E><P><V><S><G><S><L><L><Y><G><N><N><I><I><S><G><A><I><V><P><T><S><A><A><I><G><L><H><F><Y><P><I><W><E><A><S><S><V><D><E><W><L><Y...
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni...
Q6EW68
Q3B8D5
KATL2_XENLA
p60 katanin-like 2
Xenopus
<M><E><L><S><Y><Q><A><L><R><V><A><S><Q><N><R><E><A><E><E><L><R><T><E><A><R><R><K><N><L><L><I><L><I><M><H><Y><L><L><Q><E><G><Y><V><D><S><A><N><S><L><E><Q><E><T><K><I><S><S><R><R><F><E><V><C><D><N><V><D><L><E><T><I><L><M><E><Y><E><S><Y><Y><Y><I><K><F><Q><K><Y><P><K><I><T><K><K><A><L><D><H><D><S><R><V><Q><P><K><P><R><S><A...
Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.<BOP>
Q3B8D5
Q6L8H2
KRA53_HUMAN
Ultrahigh sulfur keratin-associated protein 5.3
Homo
<M><G><C><S><G><C><S><G><G><C><G><S><S><C><G><G><C><G><S><S><C><G><G><C><G><S><G><Y><G><G><C><G><S><G><C><C><V><P><V><C><C><C><K><P><V><C><C><C><V><P><A><C><S><C><S><S><C><G><S><C><G><G><S><K><G><V><C><G><S><C><G><G><C><K><G><G><C><G><S><C><G><G><S><K><G><G><C><G><S><S><C><C><V><P><V><C><C><S><S><S><C><G><S><C><G><G><S...
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hai...
Q6L8H2
Q749E9
MSCL_GEOSL
Large-conductance mechanosensitive channel
Geobacter
<M><F><K><E><F><K><E><F><A><M><K><G><N><V><V><D><L><A><I><G><V><I><I><G><G><A><F><G><K><I><V><T><S><V><V><N><D><I><V><M><P><P><I><G><L><L><M><G><K><M><D><F><S><N><L><F><I><D><L><S><G><K><G><Y><E><S><L><K><A><A><K><D><A><G><A><P><V><I><S><Y><G><A><F><I><N><T><V><L><D><F><V><I><V><A><F><V><I><F><L><V><I><K><Q><I><N><R><L...
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.<BOP>
Q749E9
Q4UJZ1
PLD_RICFE
Choline phosphatase
spotted fever group
<M><K><R><K><N><N><K><F><I><E><I><S><I><A><F><I><L><G><V><A><L><G><I><Y><G><Q><N><P><D><Y><F><T><N><L><I><N><Q><K><S><L><A><S><S><A><P><K><I><K><H><Y><N><I><S><E><L><L><R><S><K><V><S><T><C><F><T><P><P><A><G><C><T><K><F><I><A><N><Q><I><D><R><A><E><E><S><I><Y><M><Q><A><Y><G><M><S><D><A><L><I><T><T><A><L><I><N><A><Q><M><R...
Could be a virulence factor.<BOP>
Q4UJZ1
A1AUT0
PROA_PELPD
Glutamyl-gamma-semialdehyde dehydrogenase
Pelobacter
<M><T><I><A><E><Q><V><A><Q><I><A><H><E><A><R><Q><A><S><F><V><L><S><R><L><S><T><R><V><K><N><E><L><L><L><A><M><A><E><A><L><E><Q><Q><A><P><H><L><I><A><E><N><A><K><D><L><E><E><G><K><Q><K><G><L><S><S><A><M><L><D><R><L><M><L><D><A><K><R><I><S><A><M><A><D><A><L><R><E><V><A><A><L><P><D><P><V><G><E><V><T><K><M><W><K><R><P><N><N...
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP>
A1AUT0
A1KRM2
RSMG_NEIMF
16S rRNA 7-methylguanosine methyltransferase
Neisseria
<M><E><R><K><E><R><L><R><A><G><I><A><A><M><G><L><D><I><S><E><T><A><Q><D><R><L><L><A><Y><V><D><L><L><K><K><W><N><K><T><Y><N><L><T><A><L><R><D><E><E><K><M><I><V><H><H><L><L><D><S><L><T><L><L><P><H><I><E><G><V><Q><T><M><L><D><V><G><S><G><G><G><Q><P><G><I><P><A><A><V><C><R><P><D><V><Q><I><T><L><L><D><A><N><T><K><K><T><A><F...
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.<BOP>
A1KRM2
A2C249
UVRC_PROM1
Excinuclease ABC subunit C
Prochlorococcus
<M><E><L><I><P><L><I><R><D><K><S><R><L><S><D><F><L><K><D><I><P><N><D><P><G><C><Y><L><M><K><D><G><E><D><R><L><L><Y><V><G><K><S><K><K><L><R><N><R><V><R><S><Y><F><R><S><G><N><E><L><S><P><R><I><S><L><M><V><R><Q><V><A><D><I><E><L><I><V><T><D><N><E><S><E><A><L><T><L><E><S><N><L><I><K><S><H><Q><P><Y><F><N><V><L><L><K><D><D><K...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
A2C249
C6DHF6
GPPA_PECCP
pppGpp-5'-phosphohydrolase
Pectobacterium
<M><L><S><S><S><S><L><Y><A><A><I><D><L><G><S><N><S><F><H><M><L><V><A><R><E><T><A><G><S><I><Q><T><L><A><K><I><K><R><K><V><R><L><A><A><G><L><D><K><Q><N><R><L><S><Q><D><A><M><Q><R><G><W><Q><C><L><Q><L><F><S><E><R><L><Q><D><I><P><Q><D><Q><V><R><V><V><A><T><A><T><L><R><L><A><T><N><A><D><E><F><L><Q><R><A><Q><E><I><L><G><L><P...
Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activ...
C6DHF6
Q54ZI6
PLBLE_DICDI
Phospholipase B-like protein E
Dictyostelium
<M><K><L><F><I><L><L><I><V><I><V><F><L><I><S><N><S><Y><S><L><S><S><S><D><S><S><S><D><S><G><S><D><V><Q><Y><Y><S><L><T><S><Q><F><Q><V><V><Q><G><K><Q><I><P><G><S><I><A><W><G><Y><F><K><D><E><M><N><K><D><G><W><G><K><L><S><I><E><T><V><S><T><V><S><D><N><I><A><F><K><A><A><G><Y><L><E><G><Y><L><T><W><E><Y><I><Y><K><F><S><G><N><Y...
Probable phospholipase.<BOP>
Q54ZI6
Q2NSJ4
ACKA_SODGM
Acetokinase
Sodalis
<M><S><S><K><L><V><L><V><L><N><C><G><S><S><S><L><K><F><A><I><I><D><A><A><N><G><E><E><H><I><S><G><L><A><E><C><F><N><L><P><E><A><R><I><K><W><K><M><D><G><A><K><Q><E><A><A><L><G><A><G><S><A><H><S><E><A><L><H><F><I><V><N><T><I><L><A><Q><K><P><E><L><S><A><Q><L><T><A><I><G><H><R><I><V><H><G><G><E><R><F><I><Q><S><A><I><I><D><D...
Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.<BOP>
Q2NSJ4
B6ELD1
PYRD_ALISL
Dihydroorotate oxidase
Aliivibrio
<M><L><Y><R><I><A><R><A><G><I><F><K><L><D><A><E><K><A><H><D><L><A><I><Q><N><F><K><R><F><N><G><T><P><L><D><I><F><Y><R><Q><K><L><V><S><K><P><V><E><V><M><G><I><Q><F><K><N><P><I><G><L><A><A><G><L><E><K><N><G><E><C><I><E><A><F><G><A><M><G><F><G><F><I><E><V><G><T><V><T><P><R><P><Q><A><G><N><D><K><P><R><L><F><R><L><I><E><A><E...
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP>
B6ELD1
Q5FGX3
IF2_EHRRG
Translation initiation factor IF-2
Ehrlichia
<M><N><E><S><K><S><V><A><S><N><E><L><T><S><G><K><V><E><R><T><T><L><K><L><S><D><K><L><K><I><S><S><N><I><Q><Q><G><N><K><F><S><L><N><K><S><I><T><T><V><E><V><R><K><S><K><K><R><K><N><I><D><E><A><A><R><S><S><L><L><L><Q><N><N><D><I><D><G><N><S><E><D><K><N><S><L><T><I><Q><E><Q><I><S><R><M><N><A><L><Q><N><A><S><N><N><E><K><R><E...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
Q5FGX3
O05252
NUPN_BACSU
ABC transporter guanosine-binding protein NupN
Bacillus
<M><N><K><R><K><I><G><L><A><M><S><L><V><I><A><A><G><T><I><L><G><A><C><G><N><S><E><K><S><S><G><S><G><E><G><K><N><K><F><S><V><A><M><V><T><D><V><G><G><V><D><D><K><S><F><N><Q><S><A><W><E><G><I><Q><A><F><G><K><E><N><G><L><K><K><G><K><N><G><Y><D><Y><L><Q><S><K><S><D><A><D><Y><T><T><N><L><N><K><L><A><R><E><N><F><D><L><I><Y><G...
Part of an ABC transporter complex involved in the uptake of guanosine . Is probably the substrate-binding protein of the system . May be a nucleoside transporter of broad specificity but with various affinities for different substrates .<BOP>
O05252
A0L5G7
RNFB_MAGMM
Rnf electron transport complex subunit B
Magnetococcus
<M><L><E><A><V><S><A><V><M><S><L><G><G><M><A><L><F><A><G><L><G><L><G><Y><A><A><K><K><F><H><V><E><A><D><P><V><V><E><K><L><E><A><L><L><P><A><T><N><C><G><M><C><G><H><P><G><C><G><P><Y><A><Q><A><I><T><E><G><E><A><I><N><L><C><T><P><G><G><K><A><V><M><E><S><I><A><A><M><L><G><V><S><P><A><A><M><D><D><E><G><P><K><V><A><Y><I><D><E...
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.<BOP>
A0L5G7
Q9Z8N6
LPXD_CHLPN
UDP-3-O-acylglucosamine N-acyltransferase
Chlamydia
<M><S><E><A><P><V><Y><T><L><K><Q><L><A><E><L><L><Q><V><E><V><Q><G><N><I><E><T><P><I><S><G><V><E><D><I><S><Q><A><Q><P><H><H><I><A><F><L><D><N><E><K><Y><S><S><F><L><K><N><T><K><A><G><A><I><I><L><S><R><S><Q><A><M><Q><H><A><H><L><K><K><N><F><L><I><T><N><E><S><P><S><L><T><F><Q><K><C><I><E><L><F><I><E><P><V><T><S><G><F><P><G...
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q9Z8N6
Q7WGE5
BPT_BORBR
Aspartate/glutamate leucyltransferase
Bordetella
<M><P><D><M><S><Q><L><K><E><L><P><F><S><T><L><Q><F><Y><A><T><A><P><Y><P><C><S><Y><L><P><G><R><Q><A><R><S><Q><V><A><A><P><G><H><L><I><N><A><G><T><Y><S><Q><L><V><E><Q><G><F><R><R><S><G><L><F><T><Y><R><P><H><C><D><N><C><H><A><C><V><P><V><R><V><D><A><A><R><F><E><P><N><R><T><Q><R><R><A><W><R><S><H><Q><A><L><R><A><F><V><A><E...
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.<BOP>
Q7WGE5
P0DSI8
GTX3A_NEOIV
Ponericin Pi I1
Neoponera
<G><W><R><D><W><L><N><K><G><K><E><W><L><K><K><K><G><P><G><M><V><K><A><A><L><A><A><A><T><Q>
Shows a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. Has also antimicrobial activity against S.cerevisiae. Has insecticidal and non-hemolytic activity.<BOP>
P0DSI8
Q12G92
RL24_POLSJ
50S ribosomal protein L24
unclassified Polaromonas
<M><N><K><I><R><K><G><D><E><V><I><V><I><A><G><R><D><K><G><K><R><G><T><V><S><L><R><K><D><D><S><H><V><L><V><D><G><I><N><L><V><K><K><H><T><K><P><N><P><L><K><G><T><T><G><G><I><V><E><K><S><M><P><I><H><Q><S><N><V><A><I><F><N><A><A><T><G><K><A><D><R><V><G><I><K><L><L><A><D><G><K><K><V><R><V><F><K><S><S><G><D><E><I><K><A><A>
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP>
Q12G92
Q5E840
CYSI_ALIF1
Sulfite reductase [NADPH] hemoprotein beta-component
Aliivibrio
<M><S><E><L><I><D><V><K><T><I><L><S><G><T><E><L><G><P><L><A><D><N><E><R><L><K><R><E><S><K><Y><L><R><G><T><I><V><E><D><L><Q><D><R><I><T><G><G><F><T><K><D><N><F><Q><L><I><R><F><H><G><M><Y><Q><Q><D><D><R><D><I><R><A><E><R><A><K><Q><K><L><E><P><L><H><N><V><M><L><R><A><R><M><P><G><G><I><I><T><P><K><Q><W><L><A><I><D><K><F><A...
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.<BOP>
Q5E840
B8H7M2
WHIA_PSECP
Probable cell division protein WhiA
Pseudarthrobacter
<M><A><L><T><A><S><V><K><E><E><L><S><R><L><D><I><K><K><S><S><V><R><K><A><E><V><S><A><M><L><R><F><A><G><G><L><H><I><I><S><G><R><I><V><I><E><A><E><V><D><L><A><S><T><A><R><R><L><R><A><A><I><A><E><V><Y><G><H><Q><S><E><I><I><V><V><S><A><G><G><L><R><R><A><S><R><Y><V><V><R><V><V><R><D><G><E><A><L><A><R><Q><T><G><L><L><D><G><R...
Involved in cell division and chromosome segregation.<BOP>
B8H7M2
O25857
NUOH_HELPY
NDH-1 subunit H
Helicobacter
<M><S><A><Y><I><I><E><T><L><I><K><I><L><I><L><V><A><V><F><S><A><L><G><G><F><A><T><Y><I><E><R><K><V><L><A><Y><F><Q><R><R><L><G><P><C><Y><V><G><P><F><G><L><L><Q><V><A><A><D><G><I><K><L><F><T><K><E><D><I><I><P><Q><G><A><N><K><F><I><F><T><L><A><P><I><I><A><M><V><S><A><F><V><S><M><A><P><I><P><F><F><P><N><F><T><L><F><G><Y><E...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
O25857
Q110C0
RS8_TRIEI
30S ribosomal protein S8
Trichodesmium
<M><A><A><N><D><T><I><S><D><M><L><T><R><I><R><N><S><C><M><A><Q><H><T><T><T><K><V><P><A><T><K><M><T><R><S><I><A><K><V><L><K><D><E><G><F><I><G><E><F><E><Q><E><G><E><G><I><K><K><Y><L><V><I><F><L><K><Y><K><G><K><N><R><Q><P><I><I><R><Y><L><K><R><V><S><K><P><G><L><R><V><Y><K><N><R><K><E><L><P><R><V><L><G><G><I><G><I><A><I><I...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
Q110C0
A3D023
MIAA_SHEB5
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Shewanella
<M><G><P><T><A><S><G><K><T><A><L><A><L><E><L><A><E><K><H><N><C><E><I><I><S><V><D><S><A><L><I><Y><R><G><M><D><I><G><S><A><K><P><S><V><D><E><L><A><R><G><P><H><R><L><I><D><I><R><D><P><R><E><S><Y><S><A><A><D><F><R><A><D><A><I><A><E><I><E><Q><I><V><S><M><G><K><T><P><V><L><V><G><G><T><M><M><Y><F><K><A><L><L><E><G><L><S><P><L...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
A3D023
P43801
GLPC_HAEIN
Anaerobic glycerol-3-phosphate dehydrogenase subunit C
Haemophilus
<M><D><N><N><I><Q><R><L><I><D><S><A><K><Q><S><L><N><S><P><E><S><Y><K><Y><I><D><E><S><F><E><S><C><I><K><C><T><A><C><T><A><V><C><P><V><S><R><N><N><P><L><Y><P><G><P><K><Q><S><G><P><D><G><E><R><L><R><L><K><S><A><E><L><Y><D><E><A><L><K><Y><C><T><N><C><K><R><C><E><V><A><C><P><S><D><V><K><I><G><D><L><I><V><R><A><R><N><N><H><L...
Electron transfer protein; may also function as the membrane anchor for the GlpAB dimer.<BOP>
P43801
A0A0H3LX82
DTNK_BORBR
D-threonate kinase
Bordetella
<M><G><G><P><Y><I><G><I><V><A><D><D><L><T><G><S><G><D><T><A><V><Q><F><V><R><A><G><W><A><T><Q><L><S><V><G><G><A><E><Q><A><L><A><D><P><A><V><R><Q><A><E><V><L><A><V><T><T><H><S><R><P><L><A><A><A><D><A><A><A><V><V><R><G><E><V><E><R><L><R><A><A><G><V><Q><R><L><Y><K><K><V><D><S><T><L><R><G><A><F><K><A><E><I><D><A><A><R><L><A...
Catalyzes the ATP-dependent phosphorylation of D-threonate to D-threonate 4-phosphate. Can also phosphorylate 4-hydroxy-L-threonine, with lower efficiency.<BOP>
A0A0H3LX82
Q30ZK3
UVRB_OLEA2
Excinuclease ABC subunit B
Oleidesulfovibrio
<M><Q><D><S><V><F><R><I><E><S><E><Y><V><P><R><G><D><Q><P><E><A><I><T><Q><L><S><D><N><I><R><A><G><V><A><H><Q><V><L><L><G><V><T><G><S><G><K><T><F><T><M><A><H><T><I><E><R><C><Q><R><P><A><L><I><L><A><P><N><K><T><L><A><A><Q><L><Y><N><E><F><R><A><L><F><P><H><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><T><S><D...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
Q30ZK3
B7N362
KBAZ_ECO81
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ
Escherichia
<M><K><H><L><T><E><M><V><R><Q><H><K><A><G><K><T><N><G><I><Y><A><V><C><S><A><H><P><L><V><L><E><A><A><I><R><Y><A><S><A><N><Q><T><P><L><L><I><E><A><T><S><N><Q><V><D><Q><F><G><G><Y><T><G><M><T><P><A><D><F><R><G><F><V><C><Q><L><A><D><S><L><N><F><P><Q><D><A><L><I><L><G><G><D><H><L><G><P><N><R><W><Q><N><L><P><A><A><Q><A><M><A...
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity.<BOP>
B7N362
Q2T0I1
CLPS_BURTA
ATP-dependent Clp protease adapter protein ClpS
pseudomallei group
<M><A><I><I><P><D><K><Q><D><S><T><V><L><E><R><K><E><Q><K><L><K><P><P><S><M><Y><K><V><V><L><L><N><D><D><F><T><P><M><E><F><V><V><M><I><V><Q><E><Y><F><K><K><D><R><E><T><A><T><Q><I><M><L><K><V><H><R><E><G><R><G><V><C><G><V><Y><T><R><D><I><A><S><T><K><V><E><Q><V><V><T><H><A><R><Q><A><G><H><P><L><Q><C><V><M><E><E><A>
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.<BOP>
Q2T0I1
P32558
SPT16_YEAST
Suppressor of Ty protein 16
Saccharomyces
<M><E><E><L><N><I><D><F><D><V><F><K><K><R><I><E><L><L><Y><S><K><Y><N><E><F><E><G><S><P><N><S><L><L><F><V><L><G><S><S><N><A><E><N><P><Y><Q><K><T><T><I><L><H><N><W><L><L><S><Y><E><F><P><A><T><L><I><A><L><V><P><G><K><V><I><I><I><T><S><S><A><K><A><K><H><L><Q><K><A><I><D><L><F><K><D><P><E><S><K><I><T><L><E><L><W><Q><R><N><N...
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both...
P32558
Q3T0B2
PSMD6_BOVIN
26S proteasome regulatory subunit RPN7
Bos
<M><P><L><E><N><L><E><E><E><G><L><P><K><N><P><D><L><R><I><A><Q><L><R><F><L><L><S><L><P><E><H><R><G><D><A><A><V><R><D><E><L><M><A><A><V><R><D><N><N><M><A><P><Y><Y><E><A><L><C><K><S><L><E><W><Q><M><D><V><D><L><L><N><K><M><K><K><A><N><E><D><E><L><K><R><L><D><E><E><L><E><D><A><E><K><N><L><G><E><S><E><I><R><D><A><M><M><A><K...
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions ...
Q3T0B2
B1IP47
MALT_ECOLC
ATP-dependent transcriptional activator MalT
Escherichia
<M><L><I><P><S><K><L><S><R><P><V><R><L><D><H><T><V><V><R><E><R><L><L><A><K><L><S><G><A><N><N><F><R><L><A><L><I><T><S><P><A><G><Y><G><K><T><T><L><I><S><Q><W><A><A><G><K><N><D><I><G><W><Y><S><L><D><E><G><D><N><Q><Q><E><R><F><A><S><Y><L><I><A><A><V><Q><Q><A><T><N><G><H><C><A><I><C><E><T><M><A><Q><K><R><Q><Y><A><S><L><T><S...
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.<BOP>
B1IP47
Q16AC9
RL6_ROSDO
50S ribosomal protein L6
Roseobacter
<M><S><R><I><G><K><K><P><V><D><L><P><A><G><V><S><A><S><V><S><G><Q><T><I><E><I><K><G><P><K><G><T><R><A><F><K><A><T><D><D><V><T><L><T><V><E><D><N><V><V><T><V><T><P><R><G><K><S><K><R><A><R><Q><Q><W><G><M><S><R><T><M><V><A><N><L><V><T><G><V><S><E><G><F><K><K><E><L><E><I><Q><G><V><G><Y><R><A><A><M><T><G><N><T><L><K><L><N><L...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q16AC9
P51245
ATPF2_PORPU
ATPase subunit II
Porphyra
<M><I><Y><L><P><L><L><L><A><E><E><I><E><G><G><L><F><D><F><N><G><T><L><P><L><M><A><L><Q><F><L><I><L><M><L><L><L><N><T><I><F><Y><K><P><V><T><K><I><L><D><E><R><D><E><Y><I><R><T><T><L><T><T><A><S><S><M><L><V><K><A><D><E><L><A><A><K><Y><E><E><D><L><S><K><A><R><R><D><A><Q><A><K><I><A><A><S><Q><K><D><A><Q><S><I><V><S><E><D><I...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.<BOP>
P51245
Q2LRN9
EFP_SYNAS
Elongation factor P
Syntrophus
<M><Y><S><A><S><D><L><R><K><N><L><R><I><K><L><E><G><D><P><Y><I><I><T><E><F><N><F><V><K><P><G><K><G><Q><A><L><Y><R><C><K><L><K><N><M><I><T><G><N><Q><F><E><R><T><F><R><S><V><D><N><F><E><A><A><D><L><Q><E><K><K><M><Q><F><L><Y><T><E><E><D><R><Y><C><F><M><D><N><T><S><Y><E><Q><I><F><L><T><A><D><Q><V><G><D><A><A><H><F><L><I><D...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
Q2LRN9
B3Q8S3
DABA_RHOPT
Probable inorganic carbon transporter subunit DabA
Rhodopseudomonas
<M><L><M><T><K><P><P><V><P><Q><L><N><L><T><A><V><H><E><A><A><E><R><A><A><R><A><I><P><P><L><W><P><L><E><S><S><V><A><V><N><P><F><L><G><Q><I><G><E><P><L><A><V><A><A><A><R><L><R><R><V><A><G><A><A><V><T><M><P><R><A><W><Y><A><E><R><I><A><S><G><E><L><S><D><V><D><L><A><A><A><I><D><A><A><T><P><T><T><R><P><L><T><I><A><E><L><K><R...
Part of an energy-coupled inorganic carbon pump.<BOP>
B3Q8S3
B7IVG6
COAD_BACC2
Pantetheine-phosphate adenylyltransferase
Bacillus cereus group
<M><T><S><I><A><I><S><S><G><S><F><D><P><I><T><L><G><H><L><D><I><I><K><R><G><A><K><V><F><D><E><V><Y><V><V><V><L><N><N><S><S><K><K><P><F><F><S><V><E><E><R><L><E><L><I><R><E><A><T><K><D><I><P><N><V><K><V><D><S><H><S><G><L><L><V><E><Y><A><K><M><R><N><A><N><A><I><L><R><G><L><R><A><V><S><D><F><E><Y><E><M><Q><I><T><S><M><N><R...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
B7IVG6
P32471
EF1B_YEAST
Translation elongation factor 1B alpha
Saccharomyces
<M><A><S><T><D><F><S><K><I><E><T><L><K><Q><L><N><A><S><L><A><D><K><S><Y><I><E><G><T><A><V><S><Q><A><D><V><T><V><F><K><A><F><Q><S><A><Y><P><E><F><S><R><W><F><N><H><I><A><S><K><A><D><E><F><D><S><F><P><A><A><S><A><A><A><A><E><E><E><E><D><D><D><V><D><L><F><G><S><D><D><E><E><A><D><A><E><A><E><K><L><K><A><E><R><I><A><A><Y><N...
Catalytic subunit of the guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) of the eukaryotic elongation factor 1 complex (eEF1). Stimulates the exchange of GDP for GTP on elongation factor 1A (eEF1A), probably by displacing GDP from the nucleotide binding pocket in eEF1A. The 30-fold higher concentration of G...
P32471
P28394
RBL_CORMY
Ribulose bisphosphate carboxylase large chain
Coriaria
<G><V><G><F><K><A><G><V><K><D><Y><K><L><T><Y><Y><T><P><E><Y><E><T><K><D><T><D><I><L><A><A><F><R><V><T><P><Q><P><G><V><P><P><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><Q><I><E><P><V><A><G><E><E><N><Q><Y><I><A><Y><V><A><Y><P><L><D><L><F><E><E><G><S><V><T><N><M...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP>
P28394
Q2P5W2
YQGF_XANOM
Putative pre-16S rRNA nuclease
Xanthomonas
<M><P><E><A><G><A><I><L><P><D><G><T><V><L><G><F><D><V><G><S><R><R><I><G><V><A><V><G><T><A><L><G><A><G><A><R><A><V><A><V><I><N><V><H><A><S><G><P><D><W><D><A><L><D><R><V><H><K><E><W><R><P><D><G><L><V><V><G><D><P><L><T><L><D><D><K><H><Q><P><A><R><K><R><A><H><A><F><A><R><Q><L><R><E><R><Y><A><L><P><V><V><L><I><D><E><R><S><S...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
Q2P5W2
Q9XB53
KDUI_PECCC
DKI isomerase
Pectobacterium
<M><D><V><R><Q><S><V><H><S><E><H><A><K><T><L><D><T><T><E><L><R><K><K><F><L><I><E><Q><I><F><T><P><N><Q><Y><T><M><T><Y><S><H><I><D><R><I><V><V><G><G><I><M><P><V><D><G><E><I><T><F><D><D><G><I><G><K><Q><F><G><V><N><Y><F><L><E><R><R><E><L><G><L><I><N><I><G><G><P><A><K><I><V><I><D><G><T><S><Y><E><V><G><N><E><E><A><L><Y><V><G...
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.<BOP>
Q9XB53
Q1WUZ8
RF3_LIGS1
Peptide chain release factor 3
Ligilactobacillus
<M><D><K><K><Q><L><E><E><S><V><N><N><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><Q><L><L><L><F><G><G><V><V><R><K><A><G><T><V><K><A><K><K><S><G><N><F><A><K><S><D><W><M><E><I><E><K><K><R><G><I><S><V><T><S><S><V><M><Q><F><D><Y><A><G><K><R><V><N><I><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><M><A><V><D...
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP>
Q1WUZ8
Q2ST16
PTH_MYCCT
Peptidyl-tRNA hydrolase
Mycoplasma
<M><K><V><I><I><G><L><G><N><I><G><K><E><Y><E><K><T><R><H><N><A><G><F><I><A><I><D><L><L><L><E><K><Y><K><Y><N><S><I><K><E><E><F><N><S><L><V><Y><T><S><I><I><N><N><Q><K><V><L><F><V><K><P><L><T><F><M><N><N><S><G><L><T><V><K><Q><I><I><N><F><Y><K><I><D><L><N><D><L><I><V><I><H><D><D><K><D><L><N><I><S><R><I><Q><F><K><K><D><G><S...
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP>
Q2ST16
Q4L808
PYRG_STAHJ
UTP--ammonia ligase
Staphylococcus
<M><T><K><F><I><F><V><T><G><G><V><V><S><S><L><G><K><G><I><T><A><A><S><L><G><R><L><L><K><D><R><G><L><K><V><T><I><Q><K><F><D><P><Y><L><N><V><D><P><G><T><M><S><P><Y><Q><H><G><E><V><F><V><T><D><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><I><D><I><N><L><N><K><Y><S><N><V><T><A><G><K><V><Y><S><H><V><L><K><K><E><R><R><G><D><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q4L808
Q45305
MURB_BACLI
UDP-N-acetylmuramate dehydrogenase
Bacillus
<L><E><F><A><A><G><I><P><G><S><V><G><G><A><V><Y><M><N><A><G><A><H><G><S><D><I><S><R><V><L><V><K><A><L><I><L><F><E><D><G><T><I><D><W><L><T><N><E><E><M><A><F><S><Y><R><T><S><I><L><Q><N><E><R><P><G><I><C><L><E><A><V><L><Q><L><E><Q><K><E><R><D><E><I><V><A><Q><M><Q><K><N><K><D><Y><R><K><E><T><Q><P><V><S><N><P><C><A><G><S><I...
Cell wall formation.<BOP>
Q45305
Q0BE10
DNLJ_BURCM
Polydeoxyribonucleotide synthase [NAD(+)]
Burkholderia cepacia complex
<M><A><R><T><Q><A><E><P><P><A><S><Q><P><D><A><R><A><A><W><L><R><D><Q><L><E><R><A><N><Y><A><Y><Y><V><L><D><Q><P><D><L><P><D><A><E><Y><D><R><L><F><G><E><L><Q><Q><L><E><T><D><H><P><D><L><V><T><P><D><S><P><T><Q><R><V><G><G><E><V><A><G><G><F><T><P><V><V><H><D><A><P><M><L><S><L><N><N><G><F><A><D><E><D><I><A><A><F><D><K><R><V...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
Q0BE10
P10116
PA2B2_LATCO
Phospholipase A2 isozyme II
Laticauda
<N><L><I><Q><F><S><E><L><I><Q><C><A><N><K><G><K><R><A><T><Y><Y><Y><M><D><Y><G><C><Y><C><G><K><G><G><S><G><T><P><V><D><D><L><D><R><C><C><K><T><H><D><D><C><Y><G><Q><A><E><K><K><G><C><F><P><F><L><T><L><Y><N><F><I><C><F><P><G><G><P><T><C><D><R><G><T><T><C><Q><R><F><V><C><D><C><D><I><Q><A><A><F><C><F><A><R><S><P><Y><N><N><K...
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<BOP>
P10116
Q9JS04
HSCA_NEIMB
Chaperone protein HscA homolog
Neisseria
<M><A><L><L><Q><I><S><E><P><G><M><S><A><A><P><H><R><H><R><L><A><A><G><I><D><L><G><T><T><N><S><L><V><A><T><V><R><S><G><S><A><A><C><L><P><D><A><E><G><R><V><T><L><P><S><V><V><R><Y><L><E><N><G><G><I><E><V><G><K><T><A><L><S><A><Q><K><T><D><P><L><N><T><V><S><S><A><K><R><L><I><G><R><T><L><A><D><L><H><Q><N><T><H><Y><L><P><Y><R...
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.<BOP>
Q9JS04
B0SZN4
SYA_CAUSK
Alanyl-tRNA synthetase
unclassified Caulobacter
<M><P><S><L><N><E><I><R><S><T><F><L><N><Y><F><G><A><A><D><H><A><I><V><P><S><A><P><L><V><P><Q><N><D><P><T><L><L><F><V><N><A><G><M><V><P><F><K><N><V><F><T><G><A><E><T><P><P><H><P><R><A><T><S><S><Q><K><C><V><R><A><G><G><K><H><N><D><L><D><N><V><G><Y><T><A><R><H><H><T><F><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><E><Q><A><I...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
B0SZN4
Q7RZ85
NPC2_NEUCR
Phosphatidylglycerol/phosphatidylinositol transfer protein
Neurospora
<M><R><L><S><A><A><V><I><A><L><L><S><T><S><A><A><A><F><S><V><Y><R><E><N><S><V><S><A><N><D><E><L><D><V><P><G><K><S><P><L><R><F><C><D><A><A><A><D><R><K><D><D><I><V><T><I><E><E><V><I><L><T><P><N><P><P><E><A><G><Q><T><L><T><I><E><A><S><G><I><V><K><E><A><I><E><E><G><A><Y><V><N><L><Q><V><K><Y><G><Y><I><R><L><I><N><T><S><A><D...
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.<BOP>
Q7RZ85
Q9ERG5
GLHA_MESAU
Thyrotropin alpha chain
Mesocricetus
<M><D><Y><Y><R><K><Y><A><A><V><I><L><V><V><L><S><M><F><L><H><I><L><H><S><L><P><D><G><D><F><M><I><Q><G><C><P><E><C><K><L><K><E><N><K><Y><F><S><K><L><G><A><P><I><Y><Q><C><M><G><C><C><F><S><S><A><Y><P><T><P><A><R><S><K><K><T><M><L><V><P><K><N><I><T><S><E><A><T><C><C><V><A><K><A><F><T><K><A><T><V><M><G><N><A><R><V><E><N><H...
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.<BOP>
Q9ERG5
O87890
ARGC_NOSEL
N-acetyl-glutamate semialdehyde dehydrogenase
Nostoc
<M><G><N><F><G><R><V><P><V><G><I><V><G><A><S><G><Y><G><G><V><Q><L><V><R><L><L><M><D><H><P><E><I><E><L><V><Y><L><G><G><E><S><S><V><G><K><S><F><A><S><L><Y><P><H><L><A><H><A><V><K><L><S><I><E><E><V><D><P><E><V><I><A><R><R><C><E><V><V><F><L><S><M><P><N><G><L><A><C><Q><I><V><P><T><L><L><E><K><G><C><K><V><L><D><L><S><A><D><Y...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
O87890
P14751
MTR1_CERSP
Modification methylase RsrI
Cereibacter
<M><A><N><R><S><H><H><N><A><G><H><R><A><M><N><A><L><R><K><S><G><Q><K><H><S><S><E><S><Q><L><G><S><S><E><I><G><T><T><R><H><V><Y><D><V><C><D><C><L><D><T><L><A><K><L><P><D><D><S><V><Q><L><I><I><C><D><P><P><Y><N><I><M><L><A><D><W><D><D><H><M><D><Y><I><G><W><A><K><R><W><L><A><E><A><E><R><V><L><S><P><T><G><S><I><A><I><F><G><G...
A beta subtype methylase, recognizes the double-stranded sequence 5'-GAATTC-3', methylates A-3 on both strands, and protects the DNA from cleavage by the RsrI endonuclease.<BOP>
P14751
A3CPY9
NADE_STRSV
NH(3)-dependent NAD(+) synthetase
Streptococcus
<M><S><L><Q><E><E><I><I><A><Q><L><G><V><K><P><I><I><D><P><E><E><E><I><R><K><S><V><D><F><L><K><A><Y><L><K><K><H><P><F><L><K><S><Y><V><L><G><I><S><G><G><Q><D><S><T><L><A><G><R><L><A><Q><L><A><V><E><E><M><R><A><E><T><G><D><N><S><Y><R><F><I><A><V><R><L><P><Y><G><V><Q><V><D><E><D><D><A><Q><K><A><L><A><F><I><Q><A><D><V><S><L...
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.<BOP>
A3CPY9
Q5JFE7
DPHB_THEKO
Diphthamide biosynthesis methyltransferase
Thermococcus
<M><V><L><Y><F><I><G><L><G><L><Y><D><E><K><D><I><T><L><K><G><L><E><T><A><R><R><C><D><K><V><F><A><E><F><Y><T><S><L><L><A><G><T><T><L><E><K><I><E><E><L><I><G><K><P><I><V><R><L><S><R><E><D><V><E><L><N><F><E><R><I><V><L><P><E><A><K><D><K><D><V><A><F><L><T><A><G><D><P><M><V><A><T><T><H><S><D><L><R><I><R><A><K><K><A><G><V><K...
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosy...
Q5JFE7
Q12287
COX17_YEAST
Cytochrome c oxidase copper chaperone
Saccharomyces
<M><T><E><T><D><K><K><Q><E><Q><E><N><H><A><E><C><E><D><K><P><K><P><C><C><V><C><K><P><E><K><E><E><R><D><T><C><I><L><F><N><G><Q><D><S><E><K><C><K><E><F><I><E><K><Y><K><E><C><M><K><G><Y><G><F><E><V><P><S><A><N>
Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX.<BOP>
Q12287
Q9JLG4
PK2L2_MOUSE
Polycystin-L2
Mus
<M><S><E><A><T><W><W><Y><R><G><G><T><S><K><H><D><L><H><Y><R><R><E><A><E><V><N><T><T><L><E><E><L><L><L><Y><F><I><F><L><I><N><L><C><I><L><T><F><G><M><V><N><P><H><M><Y><Y><L><N><K><V><M><S><S><L><F><V><D><T><S><L><P><D><D><E><R><S><S><F><R><S><I><R><S><I><T><E><F><W><K><F><M><E><G><P><L><I><D><G><L><Y><W><D><S><W><Y><G><N...
May function as a subunit of a cation channel and play a role in fertilization.<BOP>
Q9JLG4
A9B5N7
END4_HERA2
Endonuclease IV
Herpetosiphon
<M><P><N><L><G><A><H><V><S><T><V><G><G><L><Q><T><A><F><E><R><A><Q><A><T><T><C><H><V><I><Q><I><F><T><K><S><Q><R><Q><W><N><A><K><P><L><T><A><A><D><C><A><N><F><Q><A><A><H><R><D><A><G><M><P><P><L><I><A><H><D><S><Y><L><I><N><L><G><S><P><D><N><G><L><W><E><K><S><I><A><A><F><R><V><E><L><E><R><C><Q><Q><L><G><V><G><S><L><V><T><H...
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.<BOP>
A9B5N7
B8DNB0
RS8_DESVM
30S ribosomal protein S8
Desulfovibrio
<M><L><T><D><P><I><A><D><M><L><T><R><I><R><N><A><H><L><A><L><H><K><E><V><S><V><P><R><S><K><I><K><E><S><I><A><A><I><L><K><Q><E><G><Y><I><E><D><V><A><T><E><E><A><E><I><K><I><S><L><K><Y><F><K><G><K><P><V><I><S><G><L><K><R><V><S><K><P><G><R><R><V><Y><V><G><S><T><D><I><P><K><V><Q><N><G><L><G><I><C><I><L><S><T><S><S><G><V><L...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
B8DNB0
A4XWE0
CSRA_PSEMY
Carbon storage regulator
null
<M><L><I><L><T><R><R><V><G><E><T><L><M><V><G><D><D><V><T><V><T><V><L><G><V><K><G><N><Q><V><R><I><G><V><N><A><P><K><E><V><A><V><H><R><E><E><I><Y><Q><R><I><Q><K><E><K><G><D><E><P><S><H>
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding...
A4XWE0
B2V7I6
RS4_SULSY
30S ribosomal protein S4
unclassified Sulfurihydrogenibium
<M><G><R><Y><I><G><P><L><T><K><V><S><R><R><L><G><V><F><V><G><G><D><I><E><S><F><Q><K><R><N><F><P><P><G><Q><H><G><R><T><Q><G><R><K><K><L><S><D><Y><G><V><R><L><Q><E><K><Q><K><L><R><F><L><Y><G><G><I><R><E><G><Q><F><K><R><Y><F><E><R><A><S><K><A><A><G><N><T><G><T><V><L><L><Q><L><L><E><R><R><L><D><N><V><V><Y><R><L><G><F><A><K...
With S5 and S12 plays an important role in translational accuracy.<BOP>
B2V7I6
Q1E4Z3
EIF3D_COCIM
Eukaryotic translation initiation factor 3 subunit D
Coccidioides
<M><A><P><L><S><L><T><D><I><V><S><A><L><P><S><E><E><D><A><W><G><P><P><V><P><T><G><N><H><L><D><G><V><P><Y><A><P><F><S><K><G><D><K><L><G><R><M><A><D><W><G><A><D><S><K><D><S><R><E><R><G><R><Q><A><Y><N><R><N><Y><R><D><Q><Q><V><Y><G><A><G><T><S><S><L><F><A><V><Q><V><A><E><D><E><S><S><F><S><V><V><D><N><T><R><T><S><V><K><T><R...
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically target...
Q1E4Z3
P0DN13
VKT9_ANEVI
AsKC9
Anemonia
<M><V><F><L><L><C><F><F><L><V><A><D><V><S><Y><G><I><N><K><D><C><L><L><P><M><D><V><G><R><C><R><A><R><F><P><R><Y><Y><Y><N><S><S><S><R><R><C><E><K><F><N><Y><G><G><C><G><G><N><A><N><N><F><H><T><L><E><E><C><E><K><V><C><G><V><R><S><R><D><S><P><K><E><N>
Dual-function toxin that inhibits both the serine protease trypsin and voltage-gated potassium channels Kv1.2/KCNA2.<BOP>
P0DN13
Q75HJ4
GL38_ORYSJ
Germin-like protein 3-8
Oryza sativa
<M><S><R><T><S><S><A><P><L><L><V><L><S><A><A><L><A><V><L><A><S><T><C><I><A><D><P><E><P><V><Q><D><F><C><V><A><V><V><P><R><A><G><D><A><A><A><A><A><C><P><A><Y><P><G><F><P><C><K><P><A><S><T><V><V><S><D><D><F><F><F><A><G><L><A><V><A><S><D><T><D><N><R><F><G><F><N><V><T><A><A><N><A><E><T><F><P><G><L><N><T><L><G><V><S><I><G><R...
May play a role in plant defense. Probably has no oxalate oxidase activity even if the active site is conserved.<BOP>
Q75HJ4
Q6P1Q9
MET2B_HUMAN
Methyltransferase-like protein 2B
Homo
<M><A><G><S><Y><P><E><G><A><P><A><I><L><A><D><K><R><Q><Q><F><G><S><R><F><L><S><D><P><A><R><V><F><H><H><N><A><W><D><N><V><E><W><S><E><E><Q><A><A><A><A><E><R><K><V><Q><E><N><S><I><Q><R><V><C><Q><E><K><Q><V><D><Y><E><I><N><A><H><K><Y><W><N><D><F><Y><K><I><H><E><N><G><F><F><K><D><R><H><W><L><F><T><E><F><P><E><L><A><P><S><Q...
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU).<BOP>
Q6P1Q9
P23083
HV102_HUMAN
Ig heavy chain V-I region V35
Homo
<M><D><W><T><W><R><I><L><F><L><V><A><A><A><T><G><A><H><S><Q><V><Q><L><V><Q><S><G><A><E><V><K><K><P><G><A><S><V><K><V><S><C><K><A><S><G><Y><T><F><T><G><Y><Y><M><H><W><V><R><Q><A><P><G><Q><G><L><E><W><M><G><W><I><N><P><N><S><G><G><T><N><Y><A><Q><K><F><Q><G><W><V><T><M><T><R><D><T><S><I><S><T><A><Y><M><E><L><S><R><L><R><S...
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep...
P23083
B0T135
DNAA_CAUSK
Chromosomal replication initiator protein DnaA
unclassified Caulobacter
<M><T><I><K><G><G><V><V><S><Q><D><F><S><A><A><F><S><T><V><A><C><E><P><A><G><V><V><W><N><K><V><C><T><V><L><K><R><E><L><G><D><A><A><F><G><S><W><I><A><P><A><V><L><R><E><G><P><S><G><D><V><V><V><V><T><P><T><G><I><A><R><D><W><I><R><R><S><A><W><R><R><V><S><E><L><W><T><A><N><D><A><T><G><R><R><L><D><L><K><S><R><L><E><F><E><S><V...
Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP>
B0T135
Q89G50
ILVC_BRADU
Ketol-acid reductoisomerase type I
Bradyrhizobium
<M><R><V><Y><Y><D><R><D><A><D><L><N><L><I><K><G><K><K><V><A><I><V><G><Y><G><S><Q><G><H><A><H><A><L><N><L><K><D><S><G><V><K><E><V><A><I><A><L><R><K><D><S><S><S><V><K><K><A><E><A><A><G><F><K><V><M><D><V><A><E><A><A><K><W><A><D><L><V><M><M><L><T><P><D><E><L><Q><G><D><I><Y><R><E><H><L><H><D><N><M><K><K><G><A><A><L><V><F><A...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
Q89G50
Q8NJP6
AXE1_TALPU
Acetylxylan esterase 1
Talaromyces sect. Talaromyces
<M><K><S><L><S><F><S><F><L><V><T><L><F><L><Y><L><T><L><S><S><A><R><T><L><G><K><D><V><N><K><R><V><T><A><G><S><L><Q><Q><V><T><G><F><G><D><N><A><S><G><T><L><M><Y><I><Y><V><P><K><N><L><A><T><N><P><G><I><V><V><A><I><H><Y><C><T><G><T><A><Q><A><Y><Y><T><G><S><P><Y><A><Q><L><A><E><Q><Y><G><F><I><V><I><Y><P><Q><S><P><Y><S><G><T...
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.<BOP>
Q8NJP6
Q1BZC1
PRMA_BURCA
Ribosomal protein L11 methyltransferase
Burkholderia cepacia complex
<M><S><Y><R><E><L><V><V><E><L><A><R><E><H><A><E><A><L><S><D><A><L><L><D><L><G><A><L><S><V><S><V><E><D><A><D><A><D><T><P><D><E><Q><P><L><F><G><E><P><G><L><V><P><D><R><T><A><W><Q><H><S><R><V><V><A><L><L><S><A><D><H><E><P><A><V><L><L><A><A><A><A><N><E><I><G><L><A><E><T><P><K><F><V><V><R><E><V><E><E><Q><D><W><V><R><L><T><Q...
Methylates ribosomal protein L11.<BOP>
Q1BZC1
A4SVW4
RECO_POLAQ
Recombination protein O
Polynucleobacter
<M><A><S><I><R><V><A><D><E><P><A><F><V><L><H><S><I><P><Y><K><E><T><S><L><I><L><D><V><F><T><R><Q><H><G><R><M><A><L><I><A><K><G><A><K><R><P><H><S><V><L><R><P><V><L><Q><R><F><Q><P><L><L><V><S><W><S><G><K><S><E><L><R><T><L><T><K><S><E><W><V><G><G><M><P><S><L><V><G><D><A><L><L><C><G><F><Y><L><N><E><L><L><V><K><F><L><A><R><E...
Involved in DNA repair and RecF pathway recombination.<BOP>
A4SVW4
B8IJ81
UREG_METNO
Urease accessory protein UreG
Methylobacterium
<M><T><T><S><R><H><G><P><L><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><M><E><G><L><C><K><A><L><R><A><R><Y><D><L><C><A><I><T><N><D><I><Y><T><K><E><D><A><R><L><L><T><V><A><G><A><L><P><E><E><R><I><M><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><I><N><L><A><A><V><A><E><M><R><R><R><F><P><A><L><D><L><I><L><I><E><S><G...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B8IJ81
Q92TS8
RGMG2_RHIME
Putative ribose/galactose/methyl galactoside import ATP-binding protein 2
Sinorhizobium
<M><T><L><S><P><T><T><M><A><A><V><R><A><S><G><A><V><P><K><S><E><Y><L><L><T><A><E><G><V><R><K><E><F><P><G><V><V><A><L><D><D><V><E><F><K><L><K><R><G><T><V><H><A><L><M><G><E><N><G><A><G><K><S><T><L><M><K><I><L><A><G><I><Y><Y><P><D><Q><G><E><V><K><L><R><G><A><G><I><R><L><K><S><P><L><D><A><L><E><N><G><I><A><M><I><H><Q><E><L...
Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.<BOP>
Q92TS8
O43003
MMF1_SCHPO
Maintenance of mitochondrial function 1
Schizosaccharomyces
<M><L><R><A><L><G><S><R><L><L><V><A><S><R><P><A><A><Y><R><S><F><Q><Q><S><L><R><P><V><P><R><F><F><I><H><K><M><S><T><K><T><P><I><N><S><P><K><L><S><S><A><G><P><Y><N><Q><A><I><K><A><N><G><V><I><Y><C><S><G><Q><I><P><V><A><N><G><K><V><I><E><G><T><V><G><D><Q><T><R><Q><C><L><L><N><L><Q><E><V><L><T><E><A><G><S><S><L><N><K><I><V...
Plays a role in the maintenance of mitochondrial DNA.<BOP>
O43003
C0RGK7
IHFB_BRUMB
Integration host factor subunit beta
Brucella
<M><I><K><S><E><L><V><Q><I><I><A><S><R><N><P><H><L><F><Q><R><D><V><V><N><I><V><G><A><V><F><D><E><I><T><N><A><L><A><E><G><N><R><V><E><L><R><G><F><G><A><F><S><V><K><N><R><P><A><R><S><G><R><N><P><R><T><G><E><T><V><D><V><E><E><K><W><V><P><F><F><K><T><G><K><K><L><R><D><R><L><N><G><A><V>
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
C0RGK7
A4ITQ2
UNG_GEOTN
Uracil-DNA glycosylase
Geobacillus
<M><P><I><L><K><N><D><W><A><P><L><L><E><E><E><F><Q><K><P><Y><Y><L><K><L><R><E><F><L><K><E><E><Y><R><T><R><T><I><Y><P><D><M><Y><D><I><F><N><A><L><H><Y><T><P><Y><A><N><V><K><V><V><L><L><G><Q><D><P><Y><H><G><P><G><Q><A><H><G><L><S><F><S><V><K><P><G><V><P><V><P><P><S><L><V><N><I><F><K><E><L><H><D><D><L><G><C><Y><I><P><D><N...
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP>
A4ITQ2
Q0PMG2
MDGA1_MOUSE
MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Mus
<M><E><V><T><C><L><L><L><L><A><L><I><P><F><H><C><R><G><Q><G><V><Y><A><P><A><Q><A><Q><I><V><H><A><G><Q><A><C><V><V><K><E><D><N><I><S><E><R><V><Y><T><I><R><E><S><D><T><L><V><L><Q><C><L><V><T><G><H><P><R><P><Q><V><R><W><T><K><T><A><G><S><A><S><D><K><F><Q><E><T><S><V><F><N><E><T><L><R><I><E><R><I><A><R><T><Q><G><G><R><Y><Y...
Required for radial migration of cortical neurons in the superficial layer of the neocortex. Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2.<BOP>
Q0PMG2
Q8JJ51
VM1_CROMM
Snake venom metalloproteinase
Crotalus
<M><I><E><V><L><L><V><T><I><C><L><A><V><F><P><Y><Q><G><S><S><I><I><L><E><S><G><N><V><N><D><Y><E><V><V><Y><P><R><K><V><T><A><L><P><K><G><A><V><Q><P><K><Y><E><D><A><M><Q><Y><E><L><K><V><N><G><E><P><V><V><L><H><L><E><K><N><K><E><L><F><S><K><D><Y><S><E><T><H><Y><S><P><D><G><R><K><I><T><T><N><P><S><V><E><D><H><C><Y><Y><R><G...
Snake venom metalloproteinase that impairs hemostasis in the envenomed animal.<BOP>
Q8JJ51
Q8WWZ1
IL1FA_HUMAN
Interleukin-38
Homo
<M><C><S><L><P><M><A><R><Y><Y><I><I><K><Y><A><D><Q><K><A><L><Y><T><R><D><G><Q><L><L><V><G><D><P><V><A><D><N><C><C><A><E><K><I><C><I><L><P><N><R><G><L><A><R><T><K><V><P><I><F><L><G><I><Q><G><G><S><R><C><L><A><C><V><E><T><E><E><G><P><S><L><Q><L><E><D><V><N><I><E><E><L><Y><K><G><G><E><E><A><T><R><F><T><F><F><Q><S><S><S><G...
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bact...
Q8WWZ1
A9ABP3
CCA_BURM1
Phosphatase
Burkholderia cepacia complex
<M><N><I><Y><A><V><G><G><A><I><R><D><E><L><L><G><V><P><V><Q><D><R><D><Y><V><V><V><G><A><T><P><E><Q><M><I><A><Q><G><F><R><P><V><G><K><D><F><P><V><F><L><H><P><D><T><H><E><E><Y><A><L><A><R><T><E><R><K><T><A><A><G><Y><H><G><F><Q><F><H><Y><A><P><D><V><T><L><D><E><D><L><A><R><R><D><L><T><I><N><A><M><A><R><E><V><S><P><D><G><T...
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase a...
A9ABP3
A7WXH2
ARGB_STAA1
NAG kinase
Staphylococcus
<M><K><F><I><V><I><K><I><G><G><S><T><L><S><D><M><H><P><S><I><I><N><N><I><K><H><L><R><S><N><N><I><Y><P><I><I><V><H><G><G><G><P><F><I><N><E><A><L><S><N><Q><Q><I><E><P><H><F><V><N><G><L><R><V><T><D><K><A><T><M><T><I><T><K><H><T><L><I><A><D><V><N><T><A><L><V><A><Q><F><N><Q><H><Q><C><S><A><I><G><L><C><G><L><D><A><Q><L><F><E...
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP>
A7WXH2
Q2S0L2
RNZ_SALRD
tRNase Z
Salinibacter
<M><K><I><D><V><I><P><L><G><T><A><S><A><V><P><T><D><E><R><H><L><S><A><L><A><V><E><R><K><G><Q><V><L><L><F><D><C><G><E><G><T><Q><Y><R><L><R><E><A><G><L><S><W><A><R><I><E><A><I><F><V><T><H><L><H><G><D><H><C><Y><G><L><P><G><L><L><S><T><M><E><L><Q><Q><R><A><D><P><V><T><L><V><L><P><P><G><G><P><A><M><L><R><A><V><P><G><A><T><P...
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP>
Q2S0L2
Q0MQJ5
NDUBB_PANTR
NADH-ubiquinone oxidoreductase ESSS subunit
Pan
<M><A><A><G><L><F><G><L><S><A><R><L><L><L><A><A><A><A><T><R><G><L><P><A><A><R><V><R><W><E><S><S><F><S><R><T><V><V><A><P><S><A><V><A><G><K><R><P><P><E><P><T><T><Q><W><Q><E><D><P><E><P><E><D><E><N><L><Y><E><K><N><P><D><S><H><G><Y><D><K><D><P><V><L><D><V><W><N><M><R><L><V><F><F><F><G><V><S><I><I><L><V><L><G><S><T><F><V><A...
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP>
Q0MQJ5
Q83QU0
AIS_SHIFL
Lipopolysaccharide core heptose(II)-phosphate phosphatase
Shigella
<M><L><A><F><C><R><S><S><L><K><S><K><K><Y><F><I><I><L><L><A><L><A><A><I><A><G><L><G><T><H><A><A><W><S><S><N><G><L><P><R><I><D><N><K><T><L><A><R><L><A><Q><Q><H><P><V><V><V><L><F><R><H><A><E><R><C><D><R><S><T><N><Q><C><L><S><D><K><T><G><I><T><V><K><G><T><Q><D><A><R><E><L><G><N><A><F><S><A><D><I><S><D><F><D><L><Y><S><S><N...
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.<BOP>
Q83QU0
Q9ZJG9
YIDD_HELPJ
Putative membrane protein insertion efficiency factor
Helicobacter
<M><R><N><N><K><T><P><F><L><S><A><I><F><T><A><S><I><R><G><Y><Q><R><F><F><S><A><F><T><F><S><S><C><R><F><Y><P><T><C><S><N><Y><A><L><W><L><L><C><F><E><S><P><L><V><A><M><G><K><I><A><I><R><I><L><S><C><N><P><F><C><S><G><G><I><A><Y><P><T><T><R><L><K><R><P><S><L><L><Q><S><H><K><D><F><N><R><N><F><K><T><I><T><F><W><L><V><P><T><T...
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q9ZJG9
Q4VSN2
DUSTY_TAKRU
Receptor-interacting serine/threonine-protein kinase 5
Takifugu
<M><E><G><H><G><P><Q><K><S><S><P><L><A><R><D><L><T><R><A><F><N><G><Y><H><K><Q><T><V><L><L><K><K><N><L><K><E><T><H><A><F><F><R><E><M><R><Q><N><Y><S><N><T><C><A><S><S><T><L><S><S><D><S><A><S><L><E><T><S><Q><F><S><C><I><S><F><P><S><H><E><E><E><F><L><R><N><T><V><G><A><A><P><Y><I><L><V><L><G><Q><D><C><A><A><R><Y><Q><L><L><N...
May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. May play a role in the embryonic development.<BOP>
Q4VSN2
A4Y9E3
YBEY_SHEPC
Endoribonuclease YbeY
Shewanella
<M><S><L><E><L><A><L><D><V><Q><Y><A><T><T><S><D><W><L><P><T><E><E><Q><L><M><L><W><A><K><T><A><I><G><N><G><M><D><R><A><E><L><T><I><R><I><V><D><S><R><E><S><Q><M><L><N><S><T><Y><R><G><K><D><K><P><T><N><V><L><S><F><P><F><E><A><P><A><E><I><E><L><P><L><L><G><D><L><V><I><C><A><A><V><V><E><N><E><A><R><E><Q><N><K><T><L><E><A><H...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
A4Y9E3
D8MMF7
MZRA_ERWBE
Modulator protein MzrA
Erwinia
<M><L><A><L><L><R><P><Y><L><S><T><R><V><L><C><V><L><V><V><C><F><S><A><L><M><L><V><A><F><I><P><T><L><F><R><N><D><T><A><L><Q><I><R><A><S><R><Q><G><T><T><L><P><D><G><F><Y><V><Y><Q><R><L><N><A><E><G><I><R><I><K><S><I><T><P><D><N><D><S><L><V><I><R><F><D><T><E><E><Q><S><M><A><A><E><K><V><L><H><Q><L><L><P><Y><G><F><D><I><G><Q...
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.<BOP>
D8MMF7
A3KN32
ZNF34_BOVIN
Zinc finger protein 34
Bos
<M><A><A><L><D><L><C><A><L><P><Q><A><E><V><T><F><E><D><V><A><V><F><L><S><Q><E><E><W><G><L><L><G><P><A><Q><K><G><L><Y><R><E><V><M><L><E><T><Y><R><N><L><V><S><L><G><A><G><L><A><G><P><K><P><E><V><I><A><Q><L><E><Q><G><D><E><L><W><V><L><D><M><H><G><A><E><Q><P><S><V><D><G><S><A><H><G><T><R><T><E><N><Q><E><V><T><S><G><E><M><L...
May be involved in transcriptional regulation.<BOP>
A3KN32
Q2HJ81
TBB6_BOVIN
Tubulin beta-6 chain
Bos
<M><R><E><I><V><H><I><Q><A><G><Q><C><G><N><Q><I><G><T><K><F><W><E><V><I><S><D><E><H><G><I><D><P><A><G><G><Y><V><G><D><S><A><L><Q><L><E><R><I><N><V><Y><Y><N><E><S><S><S><Q><K><Y><V><P><R><A><A><L><V><D><L><E><P><G><T><M><D><S><V><R><S><G><P><F><G><Q><L><F><R><P><D><N><F><I><F><G><Q><T><G><A><G><N><N><W><A><K><G><H><Y><T...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers . Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP...
Q2HJ81
P13858
THEM_MALCI
Thermomycolase
Malbranchea
<A><L><V><T><Q><S><N><A><P><S><W><G><L><G><R><I><S><N><R><Q><A><G><I><R><D><Y><H><Y><L><S><G><T><S><M>
This is an extracellular proteinase with a general specificity for apolar residues.<BOP>
P13858