LineageFlow / README.md
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metadata
license: mit
library_name: pytorch
tags:
  - protein-sequence-generation
  - flow-matching
  - bioinformatics
  - protein-language-models
  - pfam

LineageFlow RP55 Checkpoint

This repository hosts the released LineageFlow checkpoint for family-aware protein sequence generation.

Files

  • lineageflow-rp55.ckpt: LineageFlow denoiser checkpoint.
  • SHA256SUMS: checksum for verifying the checkpoint download.

Usage

hf download jinxbye/LineageFlow \
  lineageflow-rp55.ckpt \
  --local-dir checkpoints

See the GitHub repository for inference and evaluation code:

https://github.com/jinxbye/LineageFlow

Citation

@inproceedings{liang2026lineageflow,
  title     = {LineageFlow: Flow Matching for High-Fidelity Family-Aware Protein Sequence Generation},
  author    = {Liang, Langzhang and Yang, Ming and Feng, Yi and Li, Junfan and Pan, Shirui and Xu, Yinghui and Ying, Tianlei and Zheng, Yizhen and Xu, Zenglin},
  booktitle = {International Conference on Machine Learning},
  year      = {2026}
}