title: Biological Uncertainty Stack
emoji: 🧬
colorFrom: blue
colorTo: indigo
sdk: static
app_file: index.html
pinned: false
license: cc-by-nc-4.0
short_description: Genomic uncertainty provenance map
tags:
- genomics
- GRCh38
- biological-uncertainty
- provenance
- uncertainty-governance
- systems-integrity
- HIR
- OAM
Biological Uncertainty Stack
Biological Uncertainty Stack is a public HIR/OAM architecture map for genomic uncertainty, GRCh38 reference limits, provenance gates, measurement failure, and hard blocks against hidden positive evidence.
This Space uses the Primordial DNA Layer · GRCh38 First-Pass Architecture Plan v0.1 as its source direction. It treats GRCh38 / GRCh38.p14 as Source Layer 1: an initial baseline reference frame for first-pass feature typing and uncertainty mapping, not a complete model of human diversity and not a final biological authority.
Search target / source file
Primordial_DNA_GRCh38_First_Pass_Architecture_Plan_v0.1.html
Non-negotiable invariant
Unknown biology may preserve possibility space. Untrusted data may invalidate the comparison. Neither may be converted into hidden positive evidence.
Biological unresolvedness does not equal measurement/provenance unresolvedness. These categories must remain separate throughout all schemas, scoring, and downstream layers.
Boundary
This is a bounded architecture and public review prototype.
It is not clinical advice, diagnosis, treatment guidance, identity proof, family-relation proof, forensic conclusion, ancestry result, genetic counseling, or validated genomic-comparison software.
GRCh38 is used as a reference frame only. All genomic inferences beyond declared evidence limits are explicitly blocked by the HIR rule set.
Structural correspondence, not ontological equivalence.
Ecosystem position
This Space is part of the broader Primordial Code Ecosystem.
Parent hub: https://huggingface.co/spaces/HirModel/primordial-code-ecosystem
Collection: https://huggingface.co/collections/HirModel/primordial-code-ecosystem
This module is the biological-uncertainty and genomic provenance branch of the HIR/OAM life-first systems-integrity architecture.
Ecosystem position
This Space is part of the broader Primordial Code Ecosystem.
Parent hub: https://huggingface.co/spaces/HirModel/primordial-code-ecosystem
This module is one bounded branch of the HIR/OAM life-first systems-integrity architecture.