metadata
title: Splice Variant Effect
emoji: 🧬
colorFrom: purple
colorTo: pink
sdk: gradio
sdk_version: 6.14.0
python_version: '3.13'
app_file: app.py
pinned: false
license: agpl-3.0
suggested_hardware: t4-small
models:
- multimolecule/mmsplice
- multimolecule/mtsplice
- multimolecule/hal
- multimolecule/maxentscan-score5
- multimolecule/maxentscan-score3
- multimolecule/pangolin
- multimolecule/sptransformer
tags:
- biology
- dna
- splicing
- variant-effect
- multimolecule
Interactive splice variant-effect scoring with MultiMolecule.
Enter same-length reference and alternative DNA sequence windows, or upload a two-record FASTA file with the reference first and the alternative second. The app runs the Transformers splice-variant-effect pipeline registered by MultiMolecule and reports delta scores, optional reference and alternative scores, run metadata, and downloadable CSV/JSON outputs.
This Space intentionally works on supplied sequence windows only. It does not perform genome-coordinate lookup, transcript annotation, or reference sequence reconstruction.