| title: Splice Variant Effect | |
| emoji: 🧬 | |
| colorFrom: purple | |
| colorTo: pink | |
| sdk: gradio | |
| sdk_version: 6.14.0 | |
| python_version: "3.13" | |
| app_file: app.py | |
| pinned: false | |
| license: agpl-3.0 | |
| suggested_hardware: t4-small | |
| models: | |
| - multimolecule/mmsplice | |
| - multimolecule/mtsplice | |
| - multimolecule/hal | |
| - multimolecule/maxentscan-score5 | |
| - multimolecule/maxentscan-score3 | |
| - multimolecule/pangolin | |
| - multimolecule/sptransformer | |
| tags: | |
| - biology | |
| - dna | |
| - splicing | |
| - variant-effect | |
| - multimolecule | |
| Interactive splice variant-effect scoring with MultiMolecule. | |
| Enter same-length reference and alternative DNA sequence windows, or upload a two-record FASTA file with the reference first and the alternative second. The app runs the Transformers `splice-variant-effect` pipeline registered by MultiMolecule and reports delta scores, optional reference and alternative scores, run metadata, and downloadable CSV/JSON outputs. | |
| This Space intentionally works on supplied sequence windows only. It does not perform genome-coordinate lookup, transcript annotation, or reference sequence reconstruction. | |